Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity

Journal of Biological Chemistry

Volumn 272, Issue 40, 1997, Pages 25401-25408

  Heyeck, Stephanie D ^a   Wilcox, Heather M ^a   Bunnell, Stephen C ^a   Berg, Leslie J ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYLALANINE; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR; TYROSINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INSECT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CONSERVED SEQUENCE; ENZYME ACTIVATION; HUMANS; JURKAT CELLS; KINETICS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PHOSPHOPEPTIDES; PHOSPHORYLATION; PHOSPHOTYROSINE; POINT MUTATION; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT PROTEINS; SPODOPTERA; SRC-FAMILY KINASES; T-LYMPHOCYTES; TRANSFECTION; TYROSINE; VANADATES;

ANIMALIA; INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0030798980     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.40.25401     Document Type: Article

References (44)

1. Wange, R. L., and Samelson, L. E. (1996) Immunity 5, 197-205
2. Gibson, S., Leung, B., Squire, J. A., Hill, M., Arima, N., Goss, P., Hogg, D., and Mills, G. B. (1993) Blood 82, 1561-1571
3. Heyeck, S. D., and Berg, L. J. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 669-673
4. Siliciano, J. D., Morrow, T. A., and Desiderio, S. V. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 11194-11198
5. Tanaka, N., Asao, H., Ohtani, K., Nakamura, M., and Sugamura, K. (1993) FEBS Lett. 324, 1-5
6. Fremont, D. H., Hendrickson, W. A., Marrack, P., and Kappler, J. (1996) Science 272, 1001-1004
7. Hanissian, S. H., and Geha, R. S. (1997) Immunity 6, 379-386
8. Liao, X. C., and Littman, D. R. (1995) Immunity 3, 757-769
9. Vetrie, D., Vorechovsky, I., Sideras, P., Holland, J., Davies, A., Flinter, F., Hammarstrom, L., Kinnon, C., Levinsky, R., Bobrow, M., Smith, C. I. E., and Bentley, D. R. (1993) Nature 361, 226-232
10. Tsukada, S., Saffran, D. C., Rawlings, D. J., Parolini, O., Allen, R. C., Klisak, I., Sparkes, R. S., Kubagawa, H., Mohandas, T., Quan, S., Belmont, J. W., Cooper, M. D., Conley, M. E., and Witte, O. N. (1993) Cell 72, 279-290
11. Rawlings, D. J., Saffran, D. C., Tsukada, S., Largaespada, D. A., Grimaldi, J. C., Cohen, L., Mohr, R. N., Bazan, J. F., Howard, M., Copeland, N. G., Jenkins, N. A., and Witte, O. N. (1993) Science 261, 358-361
12. Thomas, J. D., Sideras, P., Smith, C. I. E., Vorechovsky, I., Chapman, V., and Paul, W. E. (1993) Science 261, 355-358
13. de Weers, M., Brouns, G. S., Hinshelwood, S., Kinnon, C., Schuurman, R. K. B., Hendriks, R. W., and Borst, J. (1994) J. Biol. Chem. 269, 23857-23860
14. Aoki, Y., Isselbacher, K. J., and Pillai, S. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 10606-10609
15. Kawakami, Y., Yao, L. B., Miura, T., Tsukada, S., Witte, O. N., and Kawakami, T. (1994) Mol. Cell. Biol. 14, 5108-5113
16. Saouaf, S. J., Mahajan, S., Rowley, R. B., Kut, S. A., Fargnoli, J., Burkhardt, A. L., Tsukada, S., Witte, O. N., and Holen, J. B. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9524-9528
17. Scher, I. (1982) Adv. Immunol. 33, 1-71
18. Gibson, S., August, A., Kawakami, Y., Kawakami, T., Dupont, B., and Mills, G. B. (1996) J. Immunol. 156, 2716-2722
19. Straus, D. B., and Weiss, A. (1992) Cell 70, 585-593
20. Bunnell, S. C., Henry, P. A., Kolluri, R., Kirchhausen, T., Rickles, R. J., and Berg, L. J. (1996) J. Biol. Chem. 271, 25646-25656
21. Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M., and Strober, W. (eds) (1992) Current Protocols in Immunology, Vol. 2, John Wiley & Sons, New York
22. Casnellie, J. E., Harrison, M. L., Pike, L. J., Hellstrom, K. E., and Krebs, E. G. (1982) Proc. Natl. Acad. Sci. U. S. A. 79, 282-286
23. Hellman, U., Wernstedt, C., G-ñez, J., and Heldin, C.-H. (1995) Anal. Biochem. 224, 451-455
24. Lane, W. S., Galat, A., Harding, M. W., and Schreiber, S. L. (1991) J. Protein Chem. 10, 151-160
25. August, A., Gibson, S., Kawakami, Y., Kawakami, T., Mills, G. B., and Dupont, B. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9347-9351
26. Raab, M., Cai, Y. C., Heyeck, S. D., Bunnell, S. C., Berg, L. J., and Rudd, C. E. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8891-8895
27. Gibson, S., August, A., Branch, D., Dupont, B., and Mills, G. B. (1996) J. Biol. Chem. 271, 7079-7083
28. Kamps, M. P., and Sefton, B. M. (1986) Mol. Cell. Biol. 6, 751-757
29. Hannick, M., and Donoghue, D. J. (1985) Proc. Natl. Acad. Sci. U. S.A. 82, 7894-7898
30. Weinmaster, G., Zoller, M. J., and Pawson, T. (1986) EMBO J. 5, 69-76
31. Levin, S. D., Anderson, S. J., Forbush, K. A., and Perlmutter, R. M. (1993) EMBO J. 12, 1671-1680
32. Rawlings, D. J., Scharenberg, A. M., Park, H., Wahl, M. I., Lin, S., Kato, R. M., Fluckiger, A.-C., Witte, O. N., and Kinet, J.-P. (1996) Science 271, 822-825
33. Howell, B. W., and Cooper, J. A. (1994) Mol. Cell. Biol. 14, 5402-5411
34. Johnson, L. N., Noble, M. E. M., and Owen, D. J. (1996) Cell 85, 149-158
35. King, P. D., Sadra, A., Han, A., Liu, X.-R., Sunder-Plassmann, R., Reinherz, E. L., and Dupont, B. (1996) Int. Immunol. 8, 1707-1714
36. Songyang, Z., Carraway, K. L., III, Eck, M. J., Harrison, S. C., Feldman, R. A., Mohammadi, M., Schlessigner, J., Hubbard, S. R., Smith, D. P., Eng, C., Lorenzo, M. J., Ponder, B. A. J., Mayer, B. J., and Cantley, L. C. (1995) Nature 373, 536-539
37. Park, H., Wahl, M. I., Afar, D. E. H., Turck, C. W., Rawlings, D. J., Tam, C., Scharenberg, A. M., Kinet, J., and Witte, O. N. (1996) Immunity 4, 515-525
38. Knighton, D. R., Zheng, J., Ten Eyck, L. F., Ashford, V. A., Xuong, N.-H., Taylor, S. S., and Sowadski, J. M. (1991) Science 253, 407-413
39. Mahajan, S., Fargnoli, J., Burkhardt, A. L., Kut, S. A., Saouaf, S. J., and Bolen, J. B. (1995) Mol. Cell. Biol. 15, 5304-5311
40. Afar, D. E. H., Park, H., Howell, B. W., Rawlings, D. J., Cooper, J., and Witte, O. N. (1996) Mol. Cell. Biol. 18, 3465-3471
41. Andreotti, A. H., Bunnell. S. C., Feng, S., Berg, L. J., and Schreiber, S. L. (1997) Nature 385, 93-97
42. Takata, M., and Kurosaki, T. (1996) J. Exp. Med. 184, 31-40
43. Watts, J. D., Brabb, T., Bures, E. J., Wange, R. L., Samelson, L. E., and Aebersold, R. (1996) FEBS Lett. 398, 217-222
44. King, P. D., Sadra, A., Teng, J. M. C., Liu, X.-R., Han, A., Selvakumar, A., August, A., and Dupont, B. (1997) J. Immunol. 158, 580-590