CD7-Mediated Regulation of Integrin Adhesiveness on Human T Cells Involves Tyrosine Phosphorylation-Dependent Activation of Phosphatidylinositol 3-Kinase

Journal of Immunology

Volumn 159, Issue 2, 1997, Pages 934-942

  Chan, Anissa S H ^a   Mobley, James L ^b   Fields, Gregg B ^b,c   Shimizu, Yoji ^b,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD7 ANTIGEN; INTEGRIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; TYROSINE;

ARTICLE; CELL ADHESION; HUMAN; IMMUNOLOGY; LEUKEMIA CELL LINE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIGENS, CD7; CELL ADHESION; HUMANS; INTEGRINS; JURKAT CELLS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TYROSINE;

EID: 0031570876     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (76)

1. Schwartz, M. A., M. D. Schaller, and M. H. Ginsberg. 1995. Integrins: emerging paradigms of signal transduction. Annu. Rev. Cell Biol. 11:549.
2. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301.
3. Springer, T. A. 1990. Adhesion receptors of the immune system. Nature 346:425.
4. Diamond, M. S., and T. A. Springer. 1994. The dynamic regulation of integrin adhesiveness. Curr. Biol. 4:506.
5. Dustin, M. L., and T. A. Springer. 1989. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature 341:619.
6. van Kooyk, Y., F. van de Wiel-van Kemenade, P. Weder, T. W. Kuijpers, and C. G. Figdor. 1989. Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes. Nature 342:811.
7. 1) integrin receptors on T cells. Nature 345:250.
8. Shimizu, Y., G. A. van Seventer, E. Ennis, W. Newman, K. J. Horgan, and S. Shaw. 1992. Crosslinking of the T cell-specific accessory molecules CD7 and CD28 modulates T cell adhesion. J. Exp. Med. 175:577.
9. Chan, A. S. H., P. J. Reynolds, and Y. Shimizu 1994. Tyrosine kinase activity associated with the CD7 antigen: correlation with regulation of T cell integrin function. Eur. J. Immunol. 24:2602.
10. Tanaka, Y., D. H. Adams, S. Hubscher, H. Hirano, U. Siebenlist, and S. Shaw. 1991. T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-1β. Nature 361:79.
11. Serve, H., N. S. Yee, G. Stella, L. Sepp-Lorenzino, J. C. Tan, and P. Besmer. 1995. Differential roles of PI 3-kinase and kit tyrosine 821 in kit receptor-mediated proliferation, survival and cell adhesion in mast cells. EMBO J. 14:473.
12. Adams, D H., L. Harvath, D. P. Bottaro, R. Interrante, G. Catalano, Y. Tanaka, A. Strain, S. G. Hubscher, and S. Shaw. 1994. Hepatocyte growth factor and macrophage inflammatory protein 1β: structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells. Proc. Natl. Acad. Sci. USA 91:7144.
13. Kinashi, T., J. A. Escobedo, L. T. Williams, K. Takatsu, and T. A. Springer. 1995. Receptor tyrosine kinase stimulates cell-matrix adhesion by phosphatidylinositol 3 kinase and phospholipase C-γ1 pathways. Blood 86:2086.
14. Lloyd, A. R., J. J. Oppenheim, D. J. Kelvin, and D. D. Taub. 1996. Chemokines regulate T cell adherence to recombinant adhesion molecules and extracellular matrix proteins. J. Immunol. 156:932.
15. Carr, M. W., R. Alon, and T. A. Springer. 1996. The C-C chemokine MCP-1 deferentially modulates the avidity of β1 and β2 integrins on T lymphocytes. Immunity 4:179.
16. Haynes, B. H., M. E. Martin, H. H. Kay, and J. Kurtzberg. 1988. Early events in human T cell ontogeny. Phenotypic characterization and immunohistologic localization of T cell precursors in early human fetal tissues. J. Exp. Med. 168: 1061.
17. Sato, A. I., K. B. Balamuth, K. E. Ugen, W. V. Williams, and D. B. Weiner. 1994. Identification of CD7 glycoprotein as an accessory molecule in HIV-1-mediated syncytium formation and cellfree infection. J. Immunol. 152:5142.
18. 1 integrin-mediated adhesion to fibronectin. J. Immunol. 153:3504.
19. Ledbetter, J. A., C. H. June, L. S. Grosmaire, and P. S. Rubinovitch. 1987. Crosslinking of surface antigens causes mobilization of intracellular ionized calcium in T lymphocytes. Proc. Natl. Acad. Sci. USA 84:1384.
20. Rabinowich, H., L. Pricop, R. B. Herberman, and T. L. Whiteside. 1994. Expression and function of CD7 molecule on human natural killer cells. J. Immunol. 152:517.
21. Carrera, A. C., M. Rincon, F. Sanchez-Madrid, M. Lopez-Botet, and M. O. De Landazuri. 1988. Triggering of co-mitogenic signals in T cell proliferation by anti-LFA-1 (CD18, CD11a), LFA-3, and CD7 monoclonal antibodies. J. Immunol. 141:1919.
22. Jung, L. K. L., A. K. Roy, and H. R. Chakkalath. 1992. CD7 augments T cell proliferation via the interleukin-2 autocrine pathway. Cell. Immunol. 141:189.
23. Carrel, S., S. Salvi, F. Rafti, M. Favrot, C. Rapin, and R. P. Sekaly. 1991. Direct involvement of CD7 (gp40) in activation of TCR γ/δ+ T cells. Eur. J. Immunol. 21:1195.
24. Lazarovits, A. I., N. Osman, C. E. Le Feuvre, S. C. Ley, and M. J. Crumpton. 1994. CD7 is associated with CD3 and CD45 on human T cells. J. Immunol. 153:3956.
25. Pawson, T. 1995. Protein modules and signalling networks. Nature 373:573.
26. Kapeller, R., and L. C. Cantley. 1994. Phosphatidylinositol 3-kinase. Bioessays 16:565.
27. Ward, S. G., C. H. June, and D. Olive. 1996. PI 3-kinase: a pivotal pathway in T-cell activation? Immunol. Today 17:187.
28. Dudek, H., S. R. Datta, T. F. Franke, M. J. Birnbaum, R. J. Yao, G. M. Cooper, R. A. Segal, D. R. Kaplan, and M. E. Greenberg. 1997. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275:661.
29. Kauffmann-Zeh, A., P. Rodriguez-Viciana, E. Ulrich, C. Gilbert, P. Coffer, J. Downward, and G. Evan. 1997. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. Nature 385:544.
30. Pagès, F., M. Ragueneau, R. Rottapel, A. Truneh, J. Nunes, J. Imbert, and D. Olive. 1994. Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling. Nature 369:327.
31. 1 integrin activity by the CD2 antigen. J. Cell Biol. 131:1867.
32. Zell, T., S. W. Hum, III, L. D. Finkelstein, and Y. Shimizu. 1996. CD28-mediated up-regulation of β1 integrin-mediated adhesion involves phosphatidylinositol 3-kinase. J. Immunol. 156:883.
33. Shimizu, Y., and S. W. Hunt III. 1996. Regulating integrin-mediated adhesion: one more function for PI 3-kinase? Immunol. Today 17:565.
34. Ward, S. G., R. Parry, C. LeFeuvre, D. M. Sansom, J. Westwick, and A. I. Lazarovits. 1995. Antibody ligation of CD7 leads to association with phosphoinositide 3-kinase and phosphatidylinositol 3,4,5-trisphosphate formation in T lymphocytes. Eur. J. Immunol. 25:502.
35. Mobley, J. L., E. Ennis, and Y. Shimizu. 1994. Differential activation-dependent regulation of integrin function in cultured human T-leukemic cell lines. Blood 83:1039.
36. Horgan, K. J., and S. Shaw. 1991. Immuno-magnetic negative selection of lymphocyte subsets. In Current Protocols in Immunology. J. E. Coligan, A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober, eds. John Wiley and Sons, New York, p. 7.4.1.
37. Fields, C. G., D. H. Lloyd, R. L. Macdonald, K. M. Otteson, and R. L. Noble. 1991. HBTU activation for automated Fmoc solid-phase peptide synthesis. Pept. Res. 4:95.
38. Fields, C. G., A. Loffet, S. A. Kates, and G. B. Fields. 1992. The development of high-performance liquid chromatographic analysis of allyl and allyloxycarbonyl side-chain-protected phenylthiohydantoin amino acids. Anal. Biochem. 203:245.
39. King, D. S., C. G. Fields, and G. B. Fields. 1990. A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis. Int. J. Proc. Protein Res. 36:255.
40. Fields, C. G., V. L. VanDrisse, and G. B. Fields. 1993. Edman degradation sequence analysis of resin-bound peptides synthesized by 9-fluorenylmethoxycarbonyl chemistry. Pept. Res. 6:39.
41. Hara, K., K. Yonezawa, H. Sakaue, A. Ando, K. Kotani, T. Kitamura, Y. Kitamura, H. Ueda, L. Stephens, T. R. Jackson, P. T. Hawkins, R. Dhand, A. E. Clark, G. D. Holman, M. D. Waterfield, and M. Kasuga. 1994. 1-phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. Proc. Natl. Acad. Sci. USA 91:7415.
42. Cann, A. J., Y. Koyanagi, and I. S. Y. Chen. 1988. High efficiency transfection of primary human lymphocytes and studies of gene expression. Oncogene 3:123.
43. Ui, M., T. Okada, K. Hazeki, and O. Hazeki. 1995. Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem. Sci. 20:303.
44. Vlahos, C. J., W. F. Matter, K. Y. Hui, and R. F. Brown. 1994. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J. Biol. Chem. 269:5241.
45. Wennstrom, S., P. Hawkins, F. Cooke, K. Hara, K. Yonezawa, M. Kasuga, T. Jackson, L. Claesson-Welsh, and L. Stephens. 1994. Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr. Biol. 4:385.
46. Dhand, R., K. Hara, I. Hiles, B. Bax, I. Gout, G. Panayotou, M. J. Fry, K. Yonezawa, M. Kasuga, and M. D. Waterfield. 1994. PI 3-kinase: structural and functional analysis of intersubunit interactions. EMBO J. 13:511.
47. Hara, K., K. Yonezawa, H. Sakaue, K. Kotani, A. Kojima, M. D. Waterfield, and M. Kasuga. 1995. Normal activation of p70 S6 kinase by insulin in cells overexpressing dominant negative 85 kD subunit of phosphoinositide 3-kinase. Biochem. Biophys. Res. Commun. 208:735.
48. Kotani, K., K. Hara, K. Yonezawa, and M. Kasuga. 1995. Phosphoinositide 3-kinase as an upstream regulator of the small GTP-binding protein Rac in the insulin signaling of membrane ruffling. Biochem Biophys Res. Commun. 208:985.
49. Kotani, K., A. J. Carozzi, H. Sakaue, K. Hara, L. J. Robinson, S. F. Clark, K. Yonezawa, D. E. James, and M. Kasuga. 1995. Requirement for phosphoinositide 3-kinase in insulin-stimulated GLUT4 translocation in 3T3-L1 adipocytes. Biochem. Biophys. Res. Commun. 209:343.
50. Romzek, N. C., and Y. Shimizu. 1995. Modulation of T-cell integrin activity by workshop T-cell section mAb. In Leukocyte Typing V. S. Schlossman, L. Boumsell, W. Gilks, J. Harlan, T. Kishimoto, C. Morimoto, J. Ritz, S. Shaw, R. Silverstein, T. Springer, T. Tedder, and R. Todd, eds. Oxford University Press, Oxford, p. 431.
51. Mobley, J. L., P. J. Reynolds, and Y. Shimizu. 1993. Regulatory mechanisms underlying T cell integrin receptor function. Semin. Immunol. 5:227.
52. Lee, D. M., D. D. Patel, A. M. Pendergast, and B. F. Haynes. 1996. Functional association of CD7 with phosphatidylinositol 3-kinase: interaction via a YEDM motif. Int. Immunol. 8:1195.
53. Nakanishi, S., K. J. Catt, and T. Balla. 1995. A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids. Proc. Natl. Acad. Sci. USA 92:5317.
54. 2 activity in Swiss 3T3 cells: wortmannin is not a specific inhibitor of phosphatidylinositol 3-kinase. J. Biol. Chem. 270:25352.
55. Powis, G., R. Bonjouklian, M. M. Berggren, A. Gallegos, R. Abraham, C. Ashendel, L. Zalkow, W. F. Matter, J. Dodge, G. Grindey, and C. J. Vlahos. 1994. Wortmannin, a potent and selective inhibitor of phosphatidylinositol 3-kinase. Cancer Res. 54:2419.
56. 3 integrin. J. Biol. Chem. 271:6265.
57. June, C. H., J. A. Bluestone, L. M. Nadler, and C. B. Thompson. 1994. The B7 and CD28 receptor families. Immunol. Today 15:321.
58. Truitt, K. K., C. M. Hicks, and J. B. Imboden. 1994. Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells. J. Exp. Med. 179:1071.
59. Prasad, K. V. S., Y.-C. Cai, M. Raab, B. Duckworth, L. Cantley, S. E. Shoelson, and C. E. Rudd. 1994. T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif. Proc. Natl. Acad. Sci. USA 91:2834.
60. Stein, P. H., J. D. Fraser, and A. Weiss. 1994. The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3′-kinase. Mol. Cell. Biol. 14:3392.
61. Cai, Y.-C., D. Cefai, H. Schneider, M. Raab, N. Nabavi, and C. E. Rudd. 1995. Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation. Immunity 3:417.
62. Hutchcroft, J. E., and B. E. Bierer. 1996. Signaling through CD28/CTLA-4 family receptors-puzzling participation of phosphatidylinositol-3 kinase. J. Immunol. 156:4071.
63. Eberle, M., A. E. Traynor-Kaplan, L. A. Sklar, and J. Norgauer. 1990. Is there a relationship between phosphatidylinositol trisphosphate and F-actin polymerization in human neutrophils? J. Biol. Chem. 265:16725.
64. Zhang, J., M. J. Fry, M. D. Waterfield, S. Jaken, L. Liao, J. E. B. Fox, and S. E. Rittenhouse. 1992. Activated phosphoinositide 3-kinase associates with membrane skeleton in thrombin-exposed platelets. J. Biol. Chem. 267:4686.
65. Turner, L., S. G. Ward, and J. Westwick. 1995. RANTES-activated human T lymphocytes: a role for phosphoinositide 3-kinase. J. Immunol. 155:2437.
66. Lopez-Ilasaca, M., P. Crespo, P. G. Pellici, J. S. Gutkind, and R. Wetzker. 1997. Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase γ. Science 275:394.
67. Fyn regulate CD28 binding to phosphatidylinositol 3-kinase. growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation. Proc. Natl. Acad. Sci. USA 92:8891.
68. Moriya, S., A. Kazlauskas, K. Akimoto, S. Hirai, K. Mizuno, T. Takenawa, Y. Fukui, Y. Watanabe, S. Ozaki, and S. Ohno. 1996. Platelet-derived growth factor activates protein kinase C∈ through redundant and independent signaling pathways involving phospholipase Cγ or phosphatidylinositol 3-kinase. Proc. Natl. Acad. Sci. USA 93:151.
69. Nakanishi, H., K. A. Brewer, and J. H. Exton. 1993. Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 268:13.
70. 3. J. Biol. Chem. 269:32358.
71. Akimoto, K., R. Takahashi, S. Moriya, N. Nishioka, J. Takayanagi, K. Kimura, Y. Fukui, S. Osada, K. Mizuno, S. Hirai, A. Kazlauskas, and S. Ohno. 1996. EGF or PDGF receptors activate atypical PKCλ through phosphatidylinosilol 3-kinase. EMRO J. 15:788.
72. Burgering, B. M. T., and P. J. Coffer. 1995. Protein kinase B (c-Akt) in phosphatidyl-3-OH kinase signal transduction. Nature 376:599.
73. Franke, T. F., S.-I. Yang, T. O. Chan, K. Datta, A. Kazlauskas, D. K. Morrison, D. R. Kaplan, and P. N. Tsichlis. 1995. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81:727.
74. Chou, M. M., and J. Blenis. 1995. The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling. Curr. Opin. Cell Biol. 7:806.
75. Hu, Q., A. Klippel, A. J. Muslin, W. J. Fantl, and L. T. Williams. 1995. Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol 3-kinase. Science 268:100.
76. Leta, E., A. K. Roy, Z. C. Hou, and L. K. Jung. 1995. Production and characterization of the extracellular domain of human CD7 antigen: further evidence that CD7 has a role in T cell signaling. Cell. Immunol. 165:101.