-
1
-
-
0026562544
-
DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe
-
al-Khodairy, F., and Carr, A.M. (1992). DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe. EMBO J. 11, 1343-1350.
-
(1992)
EMBO J.
, vol.11
, pp. 1343-1350
-
-
Al-Khodairy, F.1
Carr, A.M.2
-
2
-
-
0028198383
-
Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast
-
al-Khodairy, F., Fotou, E., Sheldrick, K.S., Griffiths, D.J., Lehmann, A.R., and Carr, A.M. (1994). Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast. Mol. Biol. Cell 5, 147-160.
-
(1994)
Mol. Biol. Cell
, vol.5
, pp. 147-160
-
-
Al-Khodairy, F.1
Fotou, E.2
Sheldrick, K.S.3
Griffiths, D.J.4
Lehmann, A.R.5
Carr, A.M.6
-
3
-
-
0025183708
-
Basic local alignment search tool
-
Altschul, S.F., Gish, W., Miller, W., Myers, E.W., and Lipman, D.J. (1990). Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
-
(1990)
J. Mol. Biol.
, vol.215
, pp. 403-410
-
-
Altschul, S.F.1
Gish, W.2
Miller, W.3
Myers, E.W.4
Lipman, D.J.5
-
4
-
-
0032496322
-
Replication checkpoint enforced by kinases Cds1 and Chk1
-
Boddy, M.N., Furnari, B., Mondesert, O., and Russell, P. (1998). Replication checkpoint enforced by kinases Cds1 and Chk1. Science 280, 909-912.
-
(1998)
Science
, vol.280
, pp. 909-912
-
-
Boddy, M.N.1
Furnari, B.2
Mondesert, O.3
Russell, P.4
-
5
-
-
0032546360
-
Mutations of mitotic checkpoint genes in human cancers
-
Cahill, D.P., Lengauer, C., Yu, J., Riggins, G.J., Willson, J.K., Markowitz, S.D., Kinzler, K.W., and Vogelstein, B. (1998). Mutations of mitotic checkpoint genes in human cancers. Nature 392, 300-303.
-
(1998)
Nature
, vol.392
, pp. 300-303
-
-
Cahill, D.P.1
Lengauer, C.2
Yu, J.3
Riggins, G.J.4
Willson, J.K.5
Markowitz, S.D.6
Kinzler, K.W.7
Vogelstein, B.8
-
6
-
-
9244229490
-
cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein
-
Cimprich, K.A., Shin, R.B., Keith, C.T., and Schreiber, S.L. (1996). cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein. Proc. Natl. Acad. Sci. USA 93, 2850-2855.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2850-2855
-
-
Cimprich, K.A.1
Shin, R.B.2
Keith, C.T.3
Schreiber, S.L.4
-
7
-
-
0031897062
-
+ regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene
-
+ regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene. Mol. Cell. Biol. 18, 2721-2728.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2721-2728
-
-
Davey, S.1
Han, C.S.2
Ramer, S.A.3
Klassen, J.C.4
Jacobson, A.5
Eisenberger, A.6
Hopkins, K.M.7
Lieberman, H.B.8
Freyer, G.A.9
-
8
-
-
0028785586
-
The Bloom's syndrome gene product is homologous to RecQ helicases
-
Ellis, N.A., Groden, J., Ye, T.Z., Straughen, J., Lennon, D.J., Ciocci, S., Proytcheva, M., and German, J. (1995). The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 83, 655-666.
-
(1995)
Cell
, vol.83
, pp. 655-666
-
-
Ellis, N.A.1
Groden, J.2
Ye, T.Z.3
Straughen, J.4
Lennon, D.J.5
Ciocci, S.6
Proytcheva, M.7
German, J.8
-
9
-
-
0026482601
-
Fission yeast genes involved in coupling mitosis to completion of DNA replication
-
Enoch, T., Carr, A.M., and Nurse, P. (1992). Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes & Dev. 6, 2035-2046.
-
(1992)
Genes & Dev.
, vol.6
, pp. 2035-2046
-
-
Enoch, T.1
Carr, A.M.2
Nurse, P.3
-
10
-
-
0025021753
-
Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication
-
Enoch, T., and Nurse, P. (1990). Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication. Cell 60, 665-673.
-
(1990)
Cell
, vol.60
, pp. 665-673
-
-
Enoch, T.1
Nurse, P.2
-
11
-
-
0028263738
-
Construction of an improved host strain for two hybrid screening
-
Feilotter, H.E., Hannen, G.J., Ruddell, C.J., and Beach, D. (1994). Construction of an improved host strain for two hybrid screening. Nucleic Acids Res. 22, 1502-1503.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 1502-1503
-
-
Feilotter, H.E.1
Hannen, G.J.2
Ruddell, C.J.3
Beach, D.4
-
12
-
-
0027212498
-
Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins
-
Frangioni, J.V., and Neel, B.G. (1993). Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins. Anal Biochem. 210, 179-187.
-
(1993)
Anal Biochem.
, vol.210
, pp. 179-187
-
-
Frangioni, J.V.1
Neel, B.G.2
-
14
-
-
0030768948
-
Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase
-
Furnari, B., Rhind, N., and Russell, P. (1997). Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase. Science 277, 1495-1497.
-
(1997)
Science
, vol.277
, pp. 1495-1497
-
-
Furnari, B.1
Rhind, N.2
Russell, P.3
-
15
-
-
0026452949
-
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
-
Hartwell, L. (1992). Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 71, 543-546.
-
(1992)
Cell
, vol.71
, pp. 543-546
-
-
Hartwell, L.1
-
16
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
Kastan, M.B., Zhan, Q., el-Deiry, W.S., Carrier, F., Jacks, T., Walsh, W.V., Plunkett, B.S., Vogelstein, B., and Fornace, A.J., Jr. (1992). A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71, 587-597.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
Plunkett, B.S.7
Vogelstein, B.8
Fornace A.J., Jr.9
-
17
-
-
0030997787
-
+, a fission yeast gene required for S-M and DNA damage checkpoints
-
+, a fission yeast gene required for S-M and DNA damage checkpoints. Mol. Gen. Genet. 254, 389-399.
-
(1997)
Mol. Gen. Genet.
, vol.254
, pp. 389-399
-
-
Kostrub, C.F.1
Al-Khodairy, F.2
Ghazizadeh, H.3
Carr, A.M.4
Enoch, T.5
-
18
-
-
0032055748
-
Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage
-
Kostrub, C.F., Knudsen, K., Subramani, S., Enoch, T., Kostrub, C.F., Knudsen, K., Subramani, S., and Enoch, T. (1998). Hus1p, a conserved fission yeast checkpoint protein, interacts with Rad1p and is phosphorylated in response to DNA damage. EMBO J. 17, 2055-2066.
-
(1998)
EMBO J.
, vol.17
, pp. 2055-2066
-
-
Kostrub, C.F.1
Knudsen, K.2
Subramani, S.3
Enoch, T.4
Kostrub, C.F.5
Knudsen, K.6
Subramani, S.7
Enoch, T.8
-
19
-
-
0026656853
-
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
-
Kuerbitz, S.J., Plunkett, B.S., Walsh, W.V., and Kastan, M.B. (1992). Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA 89, 7491-7495.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7491-7495
-
-
Kuerbitz, S.J.1
Plunkett, B.S.2
Walsh, W.V.3
Kastan, M.B.4
-
21
-
-
0032004942
-
S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe
-
Lindsay, H.D., Griffiths, D.J., Edwards, R.J., Christensen, P.U., Murray, J.M., Osman, F., Walworth, N., and Carr, A.M. (1998). S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. Genes & Dev. 12, 382-395.
-
(1998)
Genes & Dev.
, vol.12
, pp. 382-395
-
-
Lindsay, H.D.1
Griffiths, D.J.2
Edwards, R.J.3
Christensen, P.U.4
Murray, J.M.5
Osman, F.6
Walworth, N.7
Carr, A.M.8
-
22
-
-
0026801062
-
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
-
Livingstone, L.R., White, A., Sprouse, J., Livanos, E., Jacks, T., and Tlsty, T.D. (1992). Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70, 923-935.
-
(1992)
Cell
, vol.70
, pp. 923-935
-
-
Livingstone, L.R.1
White, A.2
Sprouse, J.3
Livanos, E.4
Jacks, T.5
Tlsty, T.D.6
-
23
-
-
0025773554
-
Mutator phenotype may be required for multistage carcinogenesis
-
Loeb, L.A. (1991). Mutator phenotype may be required for multistage carcinogenesis. Cancer Res 51, 3075-3079.
-
(1991)
Cancer Res
, vol.51
, pp. 3075-3079
-
-
Loeb, L.A.1
-
24
-
-
0030071158
-
Multiple mutations in human cancers
-
Loeb, L.A., and Christians, F.C. (1996). Multiple mutations in human cancers. Mutat. Res. 350, 279-286.
-
(1996)
Mutat. Res.
, vol.350
, pp. 279-286
-
-
Loeb, L.A.1
Christians, F.C.2
-
25
-
-
0030804309
-
The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast
-
Longhese, M.P., Paciotti, V., Fraschini, R., Zaccarini, R., Plevani, P., and Lucchini, G. (1997). The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast. EMBO J. 16, 5216-5226.
-
(1997)
EMBO J.
, vol.16
, pp. 5216-5226
-
-
Longhese, M.P.1
Paciotti, V.2
Fraschini, R.3
Zaccarini, R.4
Plevani, P.5
Lucchini, G.6
-
26
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin, D., et al. (1990). Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250, 1233-1238.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
-
27
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the chk2 protein kinase
-
Matsuoka, S., Huang, M., and Elledge, S.J. (1998). Linkage of ATM to cell cycle regulation by the chk2 protein kinase. Science 282, 1893-1897.
-
(1998)
Science
, vol.282
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
28
-
-
0028880649
-
Ataxia-telangiectasia and cellular responses to DNA damage
-
Meyn, M.S. (1995). Ataxia-telangiectasia and cellular responses to DNA damage. Cancer Res 55, 5991-6001.
-
(1995)
Cancer Res
, vol.55
, pp. 5991-6001
-
-
Meyn, M.S.1
-
29
-
-
0031035528
-
Chk1 is a weel kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation
-
O'Connell, M.J., Raleigh, J.M., Verkade, H.M., and Nurse, P. (1997). Chk1 is a weel kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. EMBO J. 16, 545-554.
-
(1997)
EMBO J.
, vol.16
, pp. 545-554
-
-
O'Connell, M.J.1
Raleigh, J.M.2
Verkade, H.M.3
Nurse, P.4
-
30
-
-
0032527776
-
Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p
-
Paciotti, V., Lucchini, G., Plevani, P., and Longhese, M.P. (1998). Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p. EMBO J. 17, 4199-4209.
-
(1998)
EMBO J.
, vol.17
, pp. 4199-4209
-
-
Paciotti, V.1
Lucchini, G.2
Plevani, P.3
Longhese, M.P.4
-
31
-
-
0032540926
-
+ checkpoint gene encodes an exonuclease
-
+ checkpoint gene encodes an exonuclease. J. Biol. Chem. 273, 18332-18339.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18332-18339
-
-
Parker, A.E.1
Van De Weyer, I.2
Laus, M.C.3
Oostveen, I.4
Yon, J.5
Verhasselt, P.6
Luyten, W.H.7
-
33
-
-
0029903534
-
Cancer of the microsatellite mutator phenotype
-
Perucho, M. (1996). Cancer of the microsatellite mutator phenotype. Biol. Chem. 377, 675-684.
-
(1996)
Biol. Chem.
, vol.377
, pp. 675-684
-
-
Perucho, M.1
-
34
-
-
0031034628
-
Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast
-
Rhind, N., Furnari, B., and Russell, P. (1997). Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast. Genes & Dev. 11, 504-511.
-
(1997)
Genes & Dev.
, vol.11
, pp. 504-511
-
-
Rhind, N.1
Furnari, B.2
Russell, P.3
-
35
-
-
0026596980
-
Checkpoint controls in Schizosaccharomyces pombe: Rad1
-
Rowley, R., Subramani, S., and Young, P.G. (1992). Checkpoint controls in Schizosaccharomyces pombe: rad1. EMBO J. 11, 1335-1342.
-
(1992)
EMBO J.
, vol.11
, pp. 1335-1342
-
-
Rowley, R.1
Subramani, S.2
Young, P.G.3
-
36
-
-
0028352113
-
Xenopus embryos regulate the nuclear localization of XMyoD
-
Rupp, R.A., Snider, L., and Weintraub, H. (1994). Xenopus embryos regulate the nuclear localization of XMyoD. Genes & Dev. 8, 1311-1323.
-
(1994)
Genes & Dev.
, vol.8
, pp. 1311-1323
-
-
Rupp, R.A.1
Snider, L.2
Weintraub, H.3
-
37
-
-
0030867582
-
Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
-
Sanchez, Y., Wong, C., Thoma, R.S., Richman, R., Wu, Z., Piwnica-Worms, H., and Elledge, S.J. (1997). Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 277, 1497-1501.
-
(1997)
Science
, vol.277
, pp. 1497-1501
-
-
Sanchez, Y.1
Wong, C.2
Thoma, R.S.3
Richman, R.4
Wu, Z.5
Piwnica-Worms, H.6
Elledge, S.J.7
-
38
-
-
0029057336
-
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky, K., et al. (1995a). A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268, 1749-1753.
-
(1995)
Science
, vol.268
, pp. 1749-1753
-
-
Savitsky, K.1
-
39
-
-
0028827312
-
The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species
-
Savitsky, K., Sfes, S.; Jagle, D.A., Zio, Y., Sartiel, A., Collins, F.S., Shiloh, Y., and Rotman, G. (1995b). The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Hum. Mol. Genet. 4, 2025-2032.
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 2025-2032
-
-
Savitsky, K.1
Sfes, S.2
Jagle, D.A.3
Zio, Y.4
Sartiel, A.5
Collins, F.S.6
Shiloh, Y.7
Rotman, G.8
-
40
-
-
0028870394
-
Genomic instability and the role of p53 mutations in cancer cells
-
Smith, M.L., and Fornace, A.J., Jr. (1995). Genomic instability and the role of p53 mutations in cancer cells. Curr. Opin. Oncol. 7, 69-75.
-
(1995)
Curr. Opin. Oncol.
, vol.7
, pp. 69-75
-
-
Smith, M.L.1
Fornace A.J., Jr.2
-
41
-
-
0028864564
-
Genomic alterations and instabilities in renal cell carcinomas and their relationship to tumor pathology
-
Thrash-Bingham, C.A., Salazar, H., Freed, J.J., Greenberg, R.E., and Tartof, K.D. (1995). Genomic alterations and instabilities in renal cell carcinomas and their relationship to tumor pathology. Cancer Res. 55, 6189-6195.
-
(1995)
Cancer Res.
, vol.55
, pp. 6189-6195
-
-
Thrash-Bingham, C.A.1
Salazar, H.2
Freed, J.J.3
Greenberg, R.E.4
Tartof, K.D.5
-
42
-
-
0029000925
-
Genomic instability and cancer
-
Tlsty, T.D., Briot, A., Gualberto, A., Hall, I., Hess, S., Hixon, M., Kuppuswamy, D., Romanov, S., Sage, M., and White, A. (1995). Genomic instability and cancer. Mutat. Res. 337, 1-7.
-
(1995)
Mutat. Res.
, vol.337
, pp. 1-7
-
-
Tlsty, T.D.1
Briot, A.2
Gualberto, A.3
Hall, I.4
Hess, S.5
Hixon, M.6
Kuppuswamy, D.7
Romanov, S.8
Sage, M.9
White, A.10
-
43
-
-
0028306459
-
Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate
-
Turner, D.L., and Weintraub, H. (1994). Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes & Dev. 8, 1434-1447.
-
(1994)
Genes & Dev.
, vol.8
, pp. 1434-1447
-
-
Turner, D.L.1
Weintraub, H.2
-
45
-
-
0027208148
-
Fission yeast chk1 protein kinase links the rad checkpoint pathway to. Cdc2
-
Walworth, N., Davey, S., and Beach, D. (1993). Fission yeast chk1 protein kinase links the rad checkpoint pathway to. cdc2. Nature 363, 368-371.
-
(1993)
Nature
, vol.363
, pp. 368-371
-
-
Walworth, N.1
Davey, S.2
Beach, D.3
-
46
-
-
0029664616
-
Rad-dependent response of the chc1-encoded protein kinase at the DNA damage checkpoint
-
Walworth, N.C., and Bernards, R. (1996). rad-dependent response of the chc1-encoded protein kinase at the DNA damage checkpoint. Science 271, 353-356.
-
(1996)
Science
, vol.271
, pp. 353-356
-
-
Walworth, N.C.1
Bernards, R.2
-
47
-
-
0023712476
-
The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae
-
Weinert, T.A., and Hartwell, L.H. (1988). The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science 241, 317-322.
-
(1988)
Science
, vol.241
, pp. 317-322
-
-
Weinert, T.A.1
Hartwell, L.H.2
-
48
-
-
0025222637
-
Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage
-
Weinert, T.A., and Hartwell, L.H. (1990). Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage. Mol. Cell. Biol. 10, 6554-6564.
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 6554-6564
-
-
Weinert, T.A.1
Hartwell, L.H.2
-
49
-
-
0032560556
-
Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control
-
Wright, J.A., Keegan, K.S., Herendeen, D.R., Bentley, N.J., Carr, A.M., Hoekstra, M.F., and Concannon, P. (1998). Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control. Proc. Natl. Acad. Sci. USA 95, 7445-7450.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 7445-7450
-
-
Wright, J.A.1
Keegan, K.S.2
Herendeen, D.R.3
Bentley, N.J.4
Carr, A.M.5
Hoekstra, M.F.6
Concannon, P.7
-
50
-
-
0029821651
-
Dual roles of ATM in the cellular response to radiation and in cell growth control
-
Xu, Y., and Baltimore, D. (1996). Dual roles of ATM in the cellular response to radiation and in cell growth control. Genes & Dev. 10, 2401-2410.
-
(1996)
Genes & Dev.
, vol.10
, pp. 2401-2410
-
-
Xu, Y.1
Baltimore, D.2
-
51
-
-
0026801977
-
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
-
Yin, Y., Tainsky, M.A., Bischoff, F.Z., Strong, L.C., and Wahl, G.M. (1992). Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70, 937-948.
-
(1992)
Cell
, vol.70
, pp. 937-948
-
-
Yin, Y.1
Tainsky, M.A.2
Bischoff, F.Z.3
Strong, L.C.4
Wahl, G.M.5
|