메뉴 건너뛰기




Volumn 2, Issue 4, 2001, Pages 231-244

Mitochondrial alterations, cellular response to oxidative stress and defective degradation of protein in aging

Author keywords

Aging; Lysosome; Mitochondria; Mitochondrial DNA; Oxidative stress; Proteasome; Reactive oxygen species; Respiratory function

Indexed keywords

LIPID; MITOCHONDRIAL DNA; PROTEIN; REACTIVE OXYGEN METABOLITE;

EID: 0035685590     PISSN: 13895729     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013270512172     Document Type: Review
Times cited : (106)

References (118)
  • 15
    • 0026549468 scopus 로고
    • Control of respiration and ATP synthesis in mammalian mitochondria and cells
    • (1992) Biochem J , vol.284 , pp. 1-13
    • Brown, G.C.1
  • 23
    • 0031081410 scopus 로고    scopus 로고
    • A proposed refinement of the mitochondrial free radical theory of aging
    • (1997) BioEssays , vol.19 , pp. 161-166
    • de Grey, A.D.N.J.1
  • 32
    • 0032539704 scopus 로고    scopus 로고
    • The human LON protease binds to mitochondrial promoters in a single-stranded, site-specific, strand-specific manner
    • (1998) Biochemistry , vol.37 , pp. 1905-1909
    • Fu, G.K.1    Markovitz, D.M.2
  • 40
    • 77049308856 scopus 로고
    • A theory based on free radical and radiation chemistry
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 42
    • 0020516814 scopus 로고
    • Free radical theory of aging: Consequences of mitochondrial aging
    • (1983) Age , vol.6 , pp. 86-94
    • Harman, D.1
  • 51
    • 0032849153 scopus 로고    scopus 로고
    • The mitochondrial theory of aging: Do damaged mitochondria accumulate by delayed degeneration?
    • (1999) Exp Gerontol , vol.34 , pp. 605-612
    • Kowald, A.1
  • 54
    • 0031036917 scopus 로고    scopus 로고
    • An essential role for free radicals and derived species in signal transduction
    • (1997) FASEB J , vol.11 , pp. 118-124
    • Lander, H.M.1
  • 58
  • 69
    • 0002026429 scopus 로고    scopus 로고
    • Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin
    • (1999) Mutat Res , vol.423 , pp. 11-21
    • Lu, C.Y.1    Lee, H.C.2    Fahn, H.J.3    Wei, Y.H.4
  • 76
    • 0024366601 scopus 로고
    • Cytochrome-c-oxidase deficient cardiomyocytes in the human heart- An age-related phenomenon. A histochemical ultracytochemical study
    • (1989) Am J Pathol , vol.134 , pp. 1167-1173
    • Müller-Höcker, J.1
  • 77
    • 0025673968 scopus 로고
    • Cytochrome c oxidase deficient fibers in the limb muscle and diaphragm of man without muscular disease: An age-related alteration
    • (1990) J Neurol Sci , vol.100 , pp. 14-21
    • Müller-Höcker, J.1
  • 80
    • 0030897739 scopus 로고    scopus 로고
    • Genetic and functional changes in mitochondria associated with aging
    • (1997) Physiol Rev , vol.77 , pp. 425-464
    • Ozawa, T.1
  • 82
    • 0030581498 scopus 로고    scopus 로고
    • Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications
    • (1996) Biochim Biophys Acta , vol.1276 , pp. 87-105
    • Papa, S.1
  • 97
    • 0032169551 scopus 로고    scopus 로고
    • Ceroid/lipofuscin formation in cultured human fibroblasts: The role of oxidative stress and lysosomal proteolysis
    • (1998) Mech Ageing Dev , vol.104 , pp. 277-291
    • Terman, A.1    Brunk, U.T.2
  • 99
    • 0032730787 scopus 로고    scopus 로고
    • Ceroid/lipofuscin-loaded human fibroblasts show decreased survival time and diminished autophagocytosis during amino acid starvation
    • (1999) Exp Gerontol , vol.34 , pp. 943-957
    • Terman, A.1    Dalen, H.2    Brunk, U.T.3
  • 105
    • 0026746336 scopus 로고
    • Mitochondrial DNA alterations as aging-associated molecular events
    • (1992) Mutat Res , vol.275 , pp. 145-155
    • Wei, Y.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.