Oxidative stress, aging and the proteasomal system

Biogerontology

Volumn 1, Issue 1, 2000, Pages 31-40

  Grune, Tilman ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Aging; Oxidative stress; Proteasome; Protein oxidation; Senescence

Indexed keywords

CROSS LINKING REAGENT; CYSTEINE PROTEINASE; MULTIENZYME COMPLEX; PROTEASOME; PROTEIN;

AGING; ANIMAL; HUMAN; INTRACELLULAR FLUID; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHYSIOLOGY; PROTEIN PROCESSING; REVIEW;

AGING; ANIMALS; CROSS-LINKING REAGENTS; CYSTEINE ENDOPEPTIDASES; HUMANS; INTRACELLULAR FLUID; MULTIENZYME COMPLEXES; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS;

EID: 0034571026     PISSN: 13895729     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010037908060     Document Type: Review

References (103)

1. Adams GM, Falke S, Goldberg AL, Saughter CA, DeMartino GN and Gogol EP (1997) Structural and functional effects of PA700 and modulator protein on proteasomes. J Mol Biol 273: 646-657
2. Adams GM, Crotchett B, Slaughter CA, DeMartino GN and Gogol EP (1998) Formation of proteasome-PA700 complexes directly correlates with activation of peptidase activity. Biochemistry 37: 12927-12932
3. Agarwal S and Sohal RS (1994) Aging and proteolysis of oxidized proteins. Arch Biochem Biophys 309: 24-28
4. Anselmi B, Conconi M, Veyrat-Durebex C, Turlin E, Biville F, Alliot J and Friguet B (1998) Dietary self-selection can compensate an age-related decrease of rat liver 20S proteasome activity observed with standard diet. J Gerontol 53: B173-B179
5. Arrigo A-P and Mehlen P (1993) Hela cells proteasome interacts with leucine-rich polypeptides and contains a phosphorylated subunit. Biochem Biophys Res Comm 194: 1387-1393
6. Brunk UT and Terman A (1998) The mitochondrial-lysosomal axis theory of cellular aging. In: Cadenas E and Packer L (eds) Understanding the Process of Aging, pp 229-250. Marcel Dekker, Basel
7. Cao G and Cutler RG. (1995) Protein oxidation and aging. Arch Biochem Biophys 320: 195-201
8. Carney JM, Starke-Reed PE, Oliver CN, Landum RW, Cheng MS, Wu JF and Floyd RA (1991) Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-a -phenylnitone. Proc Natl Acad Sci USA 88: 3633-3636
9. Chu-Ping M, Slaughter CA and DeMartino GN (1992) Purification and of characterization a protein inhibitor of the 20S proteasome (macropain). Biochem Biophys Acta 1119: 303-311
10. Ciechanover A (1994) The ubiquitin-proteasome proteolytic pathway. Cell 79: 13-21
11. Conconi M and Friguet B (1997) Proteasome inactivation upon aging and on oxidation-effect of HSP 90. Mol Biol Rep 24: 45-50
12. Conconi M, Szweda LI, Levine RL, Stadtman ER and Friguet B (1996) Age-related decline of rat liver multicatalytic proteinase activity and protection from oxidative inactivation by heat-shock protein 90. Arch Biochem Biophys 331: 232-240
13. Conconi M, Petropoulos I, Emod I, Turlin E, Biville F and Friguet B (1998) Protection from oxidative inactivation of the 20S proteasome by heat-shock protein 90. Biochem J 333: 407-415
14. Coux O, Tanaka K and Goldberg A (1996) Structure and functions of the 20S and 26S proteasomes. Annu Rev Biochem 65: 801-807
15. Davies KJA (1987) Protein damage and degradation by oxygen radicals: I. General aspects. J Biol Chem 262: 9895-9901
16. Davies KJA and Delsignore ME (1987) Protein damage and degradation by oxygen radicals: III. Modification of secondary and tertiary structure. J Biol Chem 262: 9908-9913
17. Davies KJA and Lin SW (1988a) Degradation of oxidatively denatured proteins in Escherichia coli. Free Radic Biol Med 3: 215-233
18. Davies KJA and Lin SW (1988b) Oxidatively denatured proteins are degraded by an ATP-independent proteolytic pathway in Escherichia coli. Free Radic Biol Med 5: 225-236
19. Davies KJA, Delsignore ME and Lin SW (1987a) Protein damage and degradation by oxygen radicals: II. Modification of amino acids. J Biol Chem 262: 9902-9907
20. Davies KJA, Lin SW and Pacifici RE (1987b) Protein damage and degradation by oxygen radicals: IV. Degradation of denatured proteins. J Biol Chem 262: 9914-9920
21. Dean RT, Fu S, Stocker R and Davies MJ (1997) Biochemistry and pathology of radical-mediated proteinoxidation. Biochem J 324: 1-18
22. DeMartino GN, Proske RJ, Moomaw CR, Strong AA, Song X, Hisamatsu H and Tanaka K (1996) Identification, purification, and characterization of a PA700-dependent activator of the proteasome. J Biol Chem 271: 3112-3118
23. Etlinger JD, Li SX, Guo GG, and Li N (1993) Phosphorylation and ubiquitination of the 26S proteasome complex. Enzyme Protein 47: 325-329
24. Falkenburg PE, Haass C, Kloetzel PM, Niedel B, Kopp F, Kuehn L and Dahlmann B (1988) Drosophila small cytoplasmic 19S ribonucleoprotein is homologous to the rat multicatalytic proteinase. Nature 331: 190-192
25. Fearnley IM, Walker JE, Martinus RD, Jolly RD, Kirkland KB, Shaw GJ and Palmer DN (1990) The sequence of the major protein stored in ovine ceroid lipofuscinosis is identical with that of the dicyclohexylcarbodiimide-reactive proteolipid of mitochondrial ATP synthase. J Biochem 268: 751-758
26. Friguet B and Szweda LI (1997) Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxynonenal cross-linked protein. FEBS Lett 405: 21-25
27. Friguet B, Stadtman ER and Sweda LI (1994) Modification of glucose-6-phosphate dehydrogenase by 4-hydroxynonenal. Formation of cross-linked protein that inhibits the multicatalytic protease. J Biol Chem 269: 21639-21643
28. Giulivi C and Davies KJA (1993) Dityrosine and tyrosine oxidation products are endogenous markers for selective proteolysis of oxidatively modified red blood cell hemoglobin by (the 19S) proteasome. J Biol Chem 268: 8752-8759
29. Giulivi C, Pacifici RE and Davies KJA (1994) Exposure of hydrophobic moieties promotes the selective degradation of hydrogen peroxide-modified hemoglobin by the multicatalytic proteinase complex, proteasome. Arch Biochem Biophys 311: 329-341
30. Grune T and Davies KJA (1997) Breakdown of oxidized proteins as a part of secondary antioxidant defenses in mammalian cells. BioFactors 6: 165-172
31. Grune T, Reinheckel T, Joshi M and Davies KJA (1995) Proteolysis in cultured liver epithelial cells during oxidative stress: Role of the multicatalytic proteinase complex, proteasome. J Biol Chem 270: 2344-2351
32. Grune T, Reinheckel T and Davies KJA (1996) Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome. J Biol Chem 271: 15504-15509
33. Grune T, Reinheckel T and Davies KJA (1997) Degradation of oxidized proteins in mammalian cells. FASEB J 11: 526-534
34. Grune T, Blasig IE, Sitte N, Roloff B, Haseloff R and Davies KJA (1998) Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome. J Biol Chem 273: 10857-10862
35. Guo GG, Gu M and Etlinger JD (1994) 240-kDa proteasome inhibitor (CF-2) is identical to δ-aminolevulinic acid dehydratase. J Biol Chem 269: 12399-12402
36. Hamel FG, Bennett RG, Harmon KS and Duckworth WC (1997) Insulin inhibition of proteasome activity in intact cells. Biochem Biophys Res Comm 234: 671-674
37. Harries JR (1968) Release of a macromolecular protein component from human erythrocyte ghosts. Biochim Biophys Acta 150: 534-537
38. Hendil KB, Khan S and Tanaka K (1998) Simultaneous binding of PA28 and PA700 activators to 20S proteasomes. J Biochem 332: 749-754
39. Hilt W and Wolf DH (1996) Proteasomes: destruction as a programme. TIBS 21: 96-102
40. Hoffmann L and Rechsteiner M (1994) Activation of the multicatalytic protease. J Biol Chem 269: 16890-16895
41. Holmgren A (1989) Thioredoxin and glutaredoxin systems. J Biol Chem 264: 13963-13966
42. Hough R, Pratt G and Rechsteiner M (1987) Purification of two high molecular weight proteases from rabbit reticulocyte lysate. J Biol Chem 262: 8303-8313
43. Howard JC and Seeling A (1993) Peptides and the proteasome. Nature 365: 211-212
44. Hunt JV, Bottoms MA, Clare K, Skamarauskas JT and Mitchinson MJ (1994) Glucose oxidation and low-density lipoprotein-induced macrophage ceroid accumulation: possible implications for diabetic atherosclerosis. J Biochem 300: 243-249
45. Jolly RD, Douglas BV, Davey PM and Rom JE (1995) Lipofuscin in bovine muscle and brain: a model for studying age pigment. In: Kitani K, Ivy GO and Shimasaki H (eds) Lipofuscin and Ceroid Pigments, pp 283-293. S. Karger, Basel
46. Kania MA, DeMartino GN, Baumeister W and Goldberg AL (1996) The proteasome subunit, C2, contains an important site for binding of the PA28 (11S) activator. Eur J Biochem 236: 510-516
47. Katz ML, Christianson JS, Norbury NE, Gao CL, Siakotos AN and Koppang N (1994) Lysine methylation of mitochondrial ATP synthase subunit c stored in tissues of dogs with hereditary ceroid lipofuscinosis. J Biol Chem 269: 9906-9911
48. Kuckelkorn U, Frentzel S, Kraft R, Kostka S, Groetrupp M and Kloetzel P-M (1995) Incorporation of major histocompatibility complex-encoded subunits LMP2 and LMP7 changes the qualitiy of the 20S proteasome polypeptide processing products independent of interferon-γ. Eur J Immunol 25: 2605-2611
49. Levine RL, Williams JA, Stadtman ER and Shacter E (1994) Carbonyl assays for determination of oxidatively modified proteins. Meth Enzymol 233: 346-357
50. Li X, Gu M and Etlinger JD (1991) Isolation and of characterization a novel endogenous inhibitor of the proteasome. Biochemistry 30: 9709-9715
51. Li N, Lerea KM and Etlinger JD (1996) Phosphorylation of the proteasome activator PA28 is required for proteasome activation. Biochem Biophys Res Comm 225: 855-860
52. Ludemann R, Lerea KM and Etlinger JD (1993) Copurification of casein kinase II with 20S proteasomes and phosphorylation of a 30-kDa proteasome subunit. J Biol Chem 268: 17413-17417
53. Mason GG, Hendil KB and Rivett AJ (1996) Phosphorylation of proteasomes in mammalian cells. Eur J Biochem 238: 453-462
54. Mason GG, Murray RZ, Pappin D and Rivett AJ (1998) Phosphorylation of ATPase subunits of the 26S proteasome. FEBS Lett 430: 269-274
55. Mayer-Kuckuk, P., Ullrich O, Ziegler M, Grune T and Schweiger M (1999) Functional interaction of poly(ADP-ribose) with the 20S proteasome in vitro. Biochem Biophys Res Commun 259: 576-581
56. Mott JD, Pramanik BC, Moomaw CR, Afendis SJ, DeMartino GN and Slaughter CA (1994) PA28, an activator of the 20S proteasome, is composed of two nonidentical but homologous subunits. J Biol Chem 269: 31466-31471
57. Mura CV, Gong X, Taylor A, Villalobos-Molina R and Scrofano MM (1996) Effects of calorie restriction and aging on the expression of antioxidant enzymes and ubiquitin in the liver of Emory mice. Mech Aging Dev 91: 115-129
58. Murakami M, Eguchi-Kasai K, Sato K, Minohara S, Yatagai F and Kanai T (1995) Difference in heavy-iron-induced DNA double strand breaks in a mouse DNA repair-deficient mutant cell line (SL3-147) before and after chromatin proteolysis. J Rad Res Tokyo 36: 258-264
59. Nakano M, Oenzil F, Mizuno T and Gotoh S (1995) Age-related changes in the lipofuscin accumulation of brain and heart. In: Kitani K, Ivy GO and Shimasaki H (eds) Lipofuscin and Ceroid Pigments, pp 69-77. S. Karger, Basel
60. Pacifici RE and Davies KJA (1990) Protein degradation as an index of oxidative stress. Meth Enzymol 186: 485-502
61. Pacifici RE, Salo DC and Davies KJA (1989) Macroxyproteinase (M.O.P.): A 670 kDa proteinase complex that degrades oxidatively denatured proteins in red blood cells. Free Radic Biol Med 7: 521-536
62. Pacifici RE, Kono Y and Davies KJA (1993) Hydrophobicity as the signal for selective degradation of hydroxyl radical-modified hemoglobin by the multicatalytic proteinase complex, proteasome. J Biol Chem 268: 15405-15411
63. Pardo PS, Murray PF, Walz K, Franco L and Passeron S (1998) In vivo and in vitro phosphorylation of the α7/PRS1 subunit of saccharomyces cerevisiae 20S proteasome: in vitro phosphorylation by protein kinase CK2 is absolutely dependent on polylysine. Arch Biochem Biophys 349: 397-401
64. Peters JM (1994) Proteasomes. Protein degradation machines of the cell. TIBS 19: 377-382
65. Peters JM, Franke WW and Kleinschmidt JA (1994) Distinct 19S and 20S subcomplexes of the 26S proteasome and their distribution in the cnucleus and the cytoplasm. J Biol Chem 269: 7709-7718
66. Rattan SIS (1996) Synthesis, modifications, and turnover of proteins during aging. Exp Gerontol 31: 33-47
67. Rechsteiner M, Hoffman L and Dubiel W (1993) The multicatalytic and the 26S proteases. J Biol Chem 268: 6065-6068
68. Reinheckel T, Sitte N, Ullrich O, Kuckelkorn U, Davies KJA and Grune T (1998) Comperative resistance of the 20S and 26S proteasome to oxidative stress. J Biochem 335: 637-642
69. Rivett JA (1985a) Preferential degradation of the oxidatively modified form of glutamine synthetase by intracellular mammalian proteases. J Biol Chem 260: 300-305
70. Rivett JA (1985b) Purification of a liver alkaline protease which degrades oxidatively modified glutamine synthetase: Characterization as a high molecular weight cysteine proteinase. J Biol Chem 260: 12600-12606
71. Rivett AJ (1993) Proteasomes: multicatalytic proteinase complexes. Biochem J 291: 1-10
72. Rivett AJ (1998) Intracellular distribution of proteasomes. Curr Opin Immunol 10: 110-114
73. Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D and Goldberg AL (1994) Inhibitors of proteasome block the degradation of most cell proteins and the generation of peptides on MHC class I molecules. Cell 78: 761-771
74. Sahakian JA, Szweda LI, Friguet B, Kitani K and Levine RL (1995) Aging of the liver: Proteolysis of oxidatively modified glutamine synthetase. Arch Biochem Biophys 318: 411-417
75. Salo DC, Pacifici RE, Lin SW, Giulivici C and Davies KJA (1990) Superoxide dismutase undergoes proteolysis and fragmentation following oxidative modification and inactivation. J Biol Chem 265: 11919-11927
76. Schmidt M and Kloetzel P-M (1997) Biogenesis of eucariotic 20S proteasomes: the complex maturation pathway of a complex enzyme. FASEB J 11: 1235-1243
77. Scrofano MM, Shang F, Nowell Jr.TR, Gong X, Smith DE, Kelliher M, Dunning J, Mura CV and Taylor A (1998) Aging, calorie restriction and ubiquitin-dependent proteolysis in the livers of Emory mice. Mech Aging Dev 101: 277-296
78. Shang F and Taylor A (1995) Oxidative stress and recovery from oxidative stress are associated with altered ubiquitin conjugating and proteolytic activities in bovine lens epithelial cells. Biochem J 307: 297-303
79. Shang F, Gong X and Taylor A (1997) Activity of ubiquitin-dependent pathway in response to oxidative stress. J Biol Chem 272: 23086-23093
80. Shimasaki H, Maeba R, Tachibana R and Ueta N (1995) Lipid peroxidation and ceroid accumulation in macrophages cultured with oxidized low density lipoprotein. In: Kitani K, Ivy GO and Shimasaki H (eds) Lipofuscin and Ceroid Pigments, pp 39-48. S. Karger, Basel
81. Sitte N, Merker K and Grune T (1998) Proteasome-dependent degradation of oxidized proteins in MRC-5 fibroblasts. FEBS Lett 440: 399-402
82. Smith SE, Koegl M and Jentsch S (1996) Role of the ubiquitin/proteasome system in regulated protein degradation in Saccharomyces cerevistae. Biol Chem 377: 437-446
83. Sommerburg O, Ullrich O, Sitte N, von Zglinicki D, Siems W and Grune T (1998) Dose- and wavelength-dependent oxidation of crystalline by UV light - selective recognition and degradation by the 20S proteasome. Free Radic Biol Med 24: 1369-1374
84. Song X, Mott JD, von Kampen J, Pramik B, Tanaka K, Slaughter CA and DeMartino GN (1996) A model for the quaternary structure of the proteasome activator PA28. J Biol Chem 271: 26410-26417
85. Song X, von Kampen J, Slaughter CA and DeMartino GN (1997) Relative functions of the α and β subunits of the proteasome activator, PA28. J Biol Chem 272: 27994-28000
86. Stadtman ER (1990) Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences. Free Radic Biol Med 9: 315-325
87. Stadtman ER (1993) Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions. Annu Rev Biochem 62: 797-821
88. Stadtman ER, Starke-Reed PE, Oliver CN, Carney JM and Floyed RA (1992) Protein modification in aging. In: Emerit I and Chance B (eds) Free Radicals and Aging, pp 64-72. Birkhäuser Verlag, Basel
89. Starke-Reed PE and Oliver CN (1989) Protein oxidation and proteolysis during aging and oxidative stress. Arch Biochem Biophys 275: 559-567
90. Stauber WT, Fritz VK, Maltin CA and Dahlmann B (1987) Localization of a multi-catalytic, high-molecular mass proteinase in the nuclei of muscle cells. Histochem J 19: 594-597
91. Stack PR, Waxman L and Fagan JM (1996) Activation of the multicatalytic endopeptidase by oxidants. Effects on enzyme structure. Biochemistry 35: 7142-7149
92. Terman A (1995) The effect of age on formation and elimination of autophagic vacuoles in mouse hepatocytes. In: Kitani K, Ivy GO and Shimasaki H (eds) Lipofuscin and Ceroid Pigments, pp 319-325. S. Karger, Basel
93. Ullrich O, Reinheckel T, Sitte N, Hass R, Grune T and Davies KJA (1999a) Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones. Proc Natl Acad Sci USA 96: 6223-6228
94. Ullrich O, Sitte N, Sommerburg O, Sandig V, Davies KJA and Grune T (1999b) Influence of DNA binding on the degradation of oxidized histones by the 20S proteasome. Arch Biochem Biophys 362: 211-216
95. Umeda M, Manabe Y and Uchimiya H (1997) Phosphorylation of the C2 subunit of the proteasome in rice (Oryza sativa L.). FEBS Lett 403: 313-317
96. Ustrell V, Realini C, Pratt G and Rechsteiner M (1995) Human lymphoblast and erythrocyte multicatalytic proteases: differential peptidase activities and responses to the 11S regulator. FEBS Lett 376: 155-158
97. Vogt W (1995) Oxidation of methionyl residues in proteins: tools, targets, and reversal. Free Radic Biol Med 18: 93-105
98. Wilk S and Orlowski M (1980) Cation-sensitive neutral endopeptidase: Isolation and specifity of the bovine pituitary enzyme. J Neurochem 35: 1172-1182
99. Wojcik C, Tanaka K, Paweletz N, Naab U and Wilk S (1998) Proteasome activator (PA28) subunits, α, β and χ (Ki antigen) in NT2 neuronal precursor cells and HeLa S3 cells. Eur J Cell Biol 77: 151-160
100. Yin D (1992) Lipofuscin-like fluorophores can result from reactions between oxidized ascorbic acid and glutamine. Carbonylprotein cross-linking may represent a common reaction in oxygen radical and glycosylation-related ageing processes. Mech Aging Dev 62: 35-46
101. Yin D (1995) Studies on age pigments evolving into a new theory of biological aging. In: Kitani K, Ivy GO and Shimasaki H (eds) Lipofuscin and Ceroid Pigments, pp 159-170. S. Karger, Basel
102. Yin D (1996) Biochemical basis of lipofuscin, ceroid, and age pigment-like fluorophores. Free Radic Biol Med 21: 871-888
103. Zs.-Nagy I, Streiber J and Jeney F (1995) Induction of age pigment accumulation in the brain cells of young male rats through iron-injection into the cerebrospinal fluid. In: Kitani K, Ivy GO and Shimasaki H (eds) Lipofuscin and Ceroid Pigments, pp 145-156. S. Karger, Basel