-
1
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance, B., Sies, H. and Boveris, A. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59: 527-605, 1979.
-
(1979)
Physiol. Rev.
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
2
-
-
0023883150
-
Deletions of mitochondrial DNA in patients with mitochondrial myopathies
-
Holt, I.J., Harding, A.E. and Morgan-Hughes, J.A. Deletions of mitochondrial DNA in patients with mitochondrial myopathies. Nature 331: 717-719, 1988.
-
(1988)
Nature
, vol.331
, pp. 717-719
-
-
Holt, I.J.1
Harding, A.E.2
Morgan-Hughes, J.A.3
-
3
-
-
0032036939
-
Mitochondrial DNA mutations and oxidative damage in aging and diseases: An emerging paradigm of gerontology and medicine
-
Wei, Y.H. Mitochondrial DNA mutations and oxidative damage in aging and diseases: An emerging paradigm of gerontology and medicine. Proc. Natl. Sci. Counc., R.O.C., Part B: Life Sciences 22: 55-67, 1998.
-
(1998)
Proc. Natl. Sci. Counc., R.O.C., Part B: Life Sciences
, vol.22
, pp. 55-67
-
-
Wei, Y.H.1
-
4
-
-
0033525773
-
Mitochondrial diseases in man and mouse
-
Wallace, D.C. Mitochondrial diseases in man and mouse. Science 283: 1482-1488, 1999.
-
(1999)
Science
, vol.283
, pp. 1482-1488
-
-
Wallace, D.C.1
-
5
-
-
0033040309
-
Mitochondrial encephalomyopathies : The enigma of genotype versus phenotype
-
Morgan-Hughes, J.A. and Hanna, M.G. Mitochondrial encephalomyopathies : the enigma of genotype versus phenotype. Biochim. Biophys. Acta 1410: 125-145, 1999.
-
(1999)
Biochim. Biophys. Acta
, vol.1410
, pp. 125-145
-
-
Morgan-Hughes, J.A.1
Hanna, M.G.2
-
7
-
-
0025666322
-
Leu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathy
-
Leu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathy. Nature 348: 651-653, 1990.
-
(1990)
Nature
, vol.348
, pp. 651-653
-
-
Goto, Y.1
Nonaka, I.2
Horai, S.3
-
8
-
-
0024317560
-
Spontaneous Kearns-Sayre/chronic progressive external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: A slip-replication model and metabolic therapy
-
Shoffner, J.M., Lott, M.T., Voljavec, A.S., Soueidan, S.A., Costigan, D.A. and Wallace, D.C. Spontaneous Kearns-Sayre/chronic progressive external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: A slip-replication model and metabolic therapy. Proc. Natl. Acad. Sci. USA 86: 7952-7956, 1989.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 7952-7956
-
-
Shoffner, J.M.1
Lott, M.T.2
Voljavec, A.S.3
Soueidan, S.A.4
Costigan, D.A.5
Wallace, D.C.6
-
10
-
-
0025836655
-
Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction
-
Hayashi, J.I., Ohta, S., Kikuchi, A., Takemitsu, M., Goto, Y. and Nonaka, I. Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction. Proc. Natl. Acad. Sci. USA 88: 10614-10618, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 10614-10618
-
-
Hayashi, J.I.1
Ohta, S.2
Kikuchi, A.3
Takemitsu, M.4
Goto, Y.5
Nonaka, I.6
-
11
-
-
0027418625
-
Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes
-
Dawson, T.L., Gores, G.J., Nieminen, A.L., Herman, B. and Lemasters, J.J. Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes. Am. J. Physiol. 264: C961-C967, 1993.
-
(1993)
Am. J. Physiol.
, vol.264
-
-
Dawson, T.L.1
Gores, G.J.2
Nieminen, A.L.3
Herman, B.4
Lemasters, J.J.5
-
12
-
-
0032547237
-
Increase in intracellular hydrogen peroxide and upregulation of a nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells
-
Suzuki, H., Kumagai, T., Goto, A. and Sugiura, T. Increase in intracellular hydrogen peroxide and upregulation of a nuclear respiratory gene evoked by impairment of mitochondrial electron transfer in human cells. Biochem. Biophys. Res. Commun. 249: 542-545, 1998.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.249
, pp. 542-545
-
-
Suzuki, H.1
Kumagai, T.2
Goto, A.3
Sugiura, T.4
-
13
-
-
0025309791
-
Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging
-
Bandy, B. and Davison, A. J. Mitochondrial mutations may increase oxidative stress: Implications for carcinogenesis and aging. Free Radic. Biol. Med. 8: 523-539, 1990.
-
(1990)
Free Radic. Biol. Med.
, vol.8
, pp. 523-539
-
-
Bandy, B.1
Davison, A.J.2
-
14
-
-
0030056515
-
Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase
-
Pitkänen, S. and Robinson, B.H. Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase. J. Clin. Invest. 98: 345-351, 1996.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 345-351
-
-
Pitkänen, S.1
Robinson, B.H.2
-
15
-
-
1842338036
-
Excessive formation of hydroxyl radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with complex I deficiency
-
Luo, X., Pitkänen, S., Kassovska-Bartinova, S., Robinson, B.H. and Lehotay, D.C. Excessive formation of hydroxyl radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with complex I deficiency. J. Clin. Invest. 99: 2877-2822, 1997.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2877-12822
-
-
Luo, X.1
Pitkänen, S.2
Kassovska-Bartinova, S.3
Robinson, B.H.4
Lehotay, D.C.5
-
17
-
-
0025878889
-
Biological markers of oxidative stress in mitochondrial myopathies with progressive external ophthalmoplegia
-
Piccolo, G., Banfi, P., Azan, G., Rizzuto, R., Sandona, D. and Bellomo, G. Biological markers of oxidative stress in mitochondrial myopathies with progressive external ophthalmoplegia. J. Neurol. Sci. 105:57-60, 1991.
-
(1991)
J. Neurol. Sci.
, vol.105
, pp. 57-60
-
-
Piccolo, G.1
Banfi, P.2
Azan, G.3
Rizzuto, R.4
Sandona, D.5
Bellomo, G.6
-
19
-
-
0035176759
-
Enhanced oxidative damage in human cells harboring A3243G mutation of mitochondrial DNA: Implication of oxidative stress in the pathogenesis of mitochondrial diabetes
-
in press
-
Pang, C. Y., Lee, H. C. and Wei, Y. H. Enhanced oxidative damage in human cells harboring A3243G mutation of mitochondrial DNA: Implication of oxidative stress in the pathogenesis of mitochondrial diabetes. Diabet. Res. Clin. Pract., in press.
-
Diabet. Res. Clin. Pract.
-
-
Pang, C.Y.1
Lee, H.C.2
Wei, Y.H.3
-
20
-
-
0002827532
-
Group report: The role of bioenergetics and mitochondrial DNA mutations in aging and age-related diseases
-
Esser, K. and Martin, G. M., eds., Wiley, Chichester, England
-
Wallace, D. C., Bohr, V. A., Cortopassi, G., Kadenbach, B., Linn, S., Linnane, A. W., Richter, C. and Shay, J. W. (1995) Group report: the role of bioenergetics and mitochondrial DNA mutations in aging and age-related diseases. In: Molecular Aspects of Aging (Esser, K. and Martin, G. M., eds.), Wiley, Chichester, England.
-
(1995)
Molecular Aspects of Aging
-
-
Wallace, D.C.1
Bohr, V.A.2
Cortopassi, G.3
Kadenbach, B.4
Linn, S.5
Linnane, A.W.6
Richter, C.7
Shay, J.W.8
-
21
-
-
0026587335
-
Mitochondrial genetics: A paradigm for aging and degenerative disease?
-
Wallace, D.C. Mitochondrial genetics: A paradigm for aging and degenerative disease? Science 256: 628-632, 1992.
-
(1992)
Science
, vol.256
, pp. 628-632
-
-
Wallace, D.C.1
-
22
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide: General properties and effect of hyperbaric oxygen
-
Boveris, A. and Chance, B. The mitochondrial generation of hydrogen peroxide: General properties and effect of hyperbaric oxygen. Biochem. J. 134: 707-716, 1973.
-
(1973)
Biochem. J.
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
23
-
-
0033535365
-
Endogenous oxidative damage of mtDNA
-
Beckman, K.B. and Ames, B.N. Endogenous oxidative damage of mtDNA. Mutat. Res. 424: 51-58, 1999.
-
(1999)
Mutat. Res.
, vol.424
, pp. 51-58
-
-
Beckman, K.B.1
Ames, B.N.2
-
24
-
-
0026795635
-
Protein oxidation and aging
-
Stadtman, E. R. Protein oxidation and aging. Science 257: 1220-1224, 1992.
-
(1992)
Science
, vol.257
, pp. 1220-1224
-
-
Stadtman, E.R.1
-
25
-
-
0031593219
-
Lipid peroxidation, antioxidant protection and aging
-
Rikans, L.E. and Hornbrook, K.R. Lipid peroxidation, antioxidant protection and aging. Biochim. Biophys. Acta 1362: 116-127, 1997.
-
(1997)
Biochim. Biophys. Acta
, vol.1362
, pp. 116-127
-
-
Rikans, L.E.1
Hornbrook, K.R.2
-
26
-
-
0030806863
-
Superoxide anion radical, superoxide dismutase, and related matters
-
Fridovich, I. Superoxide anion radical, superoxide dismutase, and related matters. J. Biol. Chem. 272: 18515-18517, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18515-18517
-
-
Fridovich, I.1
-
27
-
-
0003536299
-
-
Clarendon Press, Oxford, England
-
Halliwell, B. and Gutteridge, J.M.C. Free Radicals in Biology and Medicine, 3rd ed., Clarendon Press, Oxford, England, 1999.
-
(1999)
Free Radicals in Biology and Medicine, 3rd Ed.
-
-
Halliwell, B.1
Gutteridge, J.M.C.2
-
28
-
-
0021996572
-
Ubisemiquinone is the electron donor for superoxide formation by complex III of heart mitochondria
-
Turrens, J.F., Alexandre, A. andLelninger, A.L. Ubisemiquinone is the electron donor for superoxide formation by Complex III of heart mitochondria. Arch. Biochem. Biophys. 237: 408-411, 1985.
-
(1985)
Arch. Biochem. Biophys.
, vol.237
, pp. 408-411
-
-
Turrens, J.F.1
Alexandre, A.2
Lelninger, A.L.3
-
29
-
-
0019891031
-
1 complex of mitochondria! electron transport chain -demonstration of QP-S radical formation
-
1 complex of mitochondria! electron transport chain -demonstration of QP-S radical formation. Biochem. Biophys. Res. Commun. 99:1411-1419, 1981.
-
(1981)
Biochem. Biophys. Res. Commun.
, vol.99
, pp. 1411-1419
-
-
Wei, Y.H.1
Scholes, C.P.2
King, T.E.3
-
30
-
-
0028268734
-
Mitochondrial oxidative damage, hydrogen peroxide release, and aging
-
Sohal, R.S. and Dubey, A. Mitochondrial oxidative damage, hydrogen peroxide release, and aging. Free Radic. Biol. Med. 16: 621-626, 1994.
-
(1994)
Free Radic. Biol. Med.
, vol.16
, pp. 621-626
-
-
Sohal, R.S.1
Dubey, A.2
-
31
-
-
0033609069
-
Mitochondrial disease in mouse results in increased oxidative stress
-
Esposito, L.A., Melov, S., Panvo, A. Cottrell, B.A. and Wallace, D. C. Mitochondrial disease in mouse results in increased oxidative stress. Proc. Natl. Acad. Sci. USA 96: 4820-4825, 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4820-4825
-
-
Esposito, L.A.1
Melov, S.2
Panvo, A.3
Cottrell, B.A.4
Wallace, D.C.5
-
32
-
-
0029071509
-
Oxidants in mitochondria: From physiology to disease
-
Richter, C., Gogvadze, V., Laffranchi, R., Schlapbach, R., Schnizer, M., Suter, M., Walter, P. and Yaffee, M. Oxidants in mitochondria: from physiology to disease. Biochim. Biophys. Acta 1271: 67-74, 1995.
-
(1995)
Biochim. Biophys. Acta
, vol.1271
, pp. 67-74
-
-
Richter, C.1
Gogvadze, V.2
Laffranchi, R.3
Schlapbach, R.4
Schnizer, M.5
Suter, M.6
Walter, P.7
Yaffee, M.8
-
33
-
-
2542505678
-
Oxidative stress and mitochondrial DNA mutations in human aging
-
Wei, Y.H. Oxidative stress and mitochondrial DNA mutations in human aging. Proc. Soc. Exp. Biol. Med. 217: 53-63, 1998.
-
(1998)
Proc. Soc. Exp. Biol. Med.
, vol.217
, pp. 53-63
-
-
Wei, Y.H.1
-
34
-
-
0032820186
-
Age-dependent changes of antioxidant activities and markers of free radical damage in human skeletal muscles
-
Pansarasa, O., Bertorelli, L., Vecchiet, J., Felzani, G. and Marzatico, F. Age-dependent changes of antioxidant activities and markers of free radical damage in human skeletal muscles. Free Radic. Biol. Med. 27: 617-622, 1999.
-
(1999)
Free Radic. Biol. Med.
, vol.27
, pp. 617-622
-
-
Pansarasa, O.1
Bertorelli, L.2
Vecchiet, J.3
Felzani, G.4
Marzatico, F.5
-
35
-
-
0023811053
-
Normal oxidative damage to mitochondrial and nuclear DNA is extensive
-
Richter, C., Park, J.W. and Ames, B.N. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc. Natl. Acad. Sci. USA 85: 6465-6467, 1988.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 6465-6467
-
-
Richter, C.1
Park, J.W.2
Ames, B.N.3
-
36
-
-
0000350066
-
Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA
-
Garcia de la Asuncion, J., Millan, A., Pla, R., Bruseghini, L., Esteras, A., Pallardo, F.V., Sastre, J. and Vina, J. Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA. FASEB J. 10: 333-338, 1996.
-
(1996)
FASEB J.
, vol.10
, pp. 333-338
-
-
Garcia De La Asuncion, J.1
Millan, A.2
Pla, R.3
Bruseghini, L.4
Esteras, A.5
Pallardo, F.V.6
Sastre, J.7
Vina, J.8
-
37
-
-
0034016125
-
Mitochondria, oxidative stress and aging
-
Sastre, J., Pallardo, F.V., Asuncion, J.G.D.L. and Vina, J. Mitochondria, oxidative stress and aging. Free Radic. Res. 32: 189-198, 2000.
-
(2000)
Free Radic. Res.
, vol.32
, pp. 189-198
-
-
Sastre, J.1
Pallardo, F.V.2
Asuncion, J.G.D.L.3
Vina, J.4
-
38
-
-
0027055332
-
Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts
-
Hayakawa, M., Hattori, K., Sugiyama, S. and Ozawa, T. Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts. Biochem. Biophys. Res. Commun. 189: 979-985, 1992.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.189
, pp. 979-985
-
-
Hayakawa, M.1
Hattori, K.2
Sugiyama, S.3
Ozawa, T.4
-
39
-
-
0027527023
-
Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain
-
Mecocci, P., MacGarvey, U., Kaufman, A.E., Koontz, D., Shoffner, J.M., Wallace, D. C. and Beal, M.F. Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain. Ann. Neurol. 34: 609-616, 1993.
-
(1993)
Ann. Neurol.
, vol.34
, pp. 609-616
-
-
Mecocci, P.1
MacGarvey, U.2
Kaufman, A.E.3
Koontz, D.4
Shoffner, J.M.5
Wallace, D.C.6
Beal, M.F.7
-
40
-
-
0033557111
-
Concurrent increase of oxidative DNA damage and lipid peroxidation together with mitochondrial DNA mutation in human lung tissues during aging-smoking enhances oxidative stress on the aged tissues
-
Lee, H.C., Lim, M.L.R., Lu, C.Y., Liu, V.W.S., Fahn, H.J., Zhang, C., Nagley, P. and Wei, Y.H. Concurrent increase of oxidative DNA damage and lipid peroxidation together with mitochondrial DNA mutation in human lung tissues during aging-smoking enhances oxidative stress on the aged tissues. Arch. Biochem. Biophys. 362: 309-316, 1999.
-
(1999)
Arch. Biochem. Biophys.
, vol.362
, pp. 309-316
-
-
Lee, H.C.1
Lim, M.L.R.2
Lu, C.Y.3
Liu, V.W.S.4
Fahn, H.J.5
Zhang, C.6
Nagley, P.7
Wei, Y.H.8
-
41
-
-
0002026429
-
Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin
-
Lu, C.Y., Lee, H.C. Fahn, H.J. and Wei, Y.H. Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin. Mutat. Res. 423: 11-21, 1999.
-
(1999)
Mutat. Res.
, vol.423
, pp. 11-21
-
-
Lu, C.Y.1
Lee, H.C.2
Fahn, H.J.3
Wei, Y.H.4
-
42
-
-
0026784592
-
Lipid peroxidation and mtDNA degeneration. A hypothesis
-
Hruszkewycz, A.M. Lipid peroxidation and mtDNA degeneration. A hypothesis. Mutat. Res. 275: 243-248, 1992.
-
(1992)
Mutat. Res.
, vol.275
, pp. 243-248
-
-
Hruszkewycz, A.M.1
-
43
-
-
0028296508
-
Age-dependent increase of mitochondrial DNA deletions together with lipid peroxides and superoxide dismutase in human liver mitochondria
-
Yen, T.C., King, K.L., Lee, H.C., Yeh, S.H. and Wei, Y.H. Age-dependent increase of mitochondrial DNA deletions together with lipid peroxides and superoxide dismutase in human liver mitochondria. Free Radic. Biol. Med. 16: 207-214, 1994.
-
(1994)
Free Radic. Biol. Med.
, vol.16
, pp. 207-214
-
-
Yen, T.C.1
King, K.L.2
Lee, H.C.3
Yeh, S.H.4
Wei, Y.H.5
-
44
-
-
0029762274
-
Simultaneous increase of mitochondrial DNA deletions and lipid peroxidation in human aging
-
Wei, Y.H., Kao, S.H. and Lee, H.C. Simultaneous increase of mitochondrial DNA deletions and lipid peroxidation in human aging. Ann. N. Y. Acad. Sci. 786: 24-43, 1996.
-
(1996)
Ann. N. Y. Acad. Sci.
, vol.786
, pp. 24-43
-
-
Wei, Y.H.1
Kao, S.H.2
Lee, H.C.3
-
45
-
-
0033984710
-
The effect of reactive oxygen species generated from the mitochondrial electron transport chain on the cytochrome c oxidase activity and on the cardiolipin content in bovine submitochondrial particles
-
Paradies, G., Petrosillo, G., Pistolese, M. and Ruggiero, F.M. The effect of reactive oxygen species generated from the mitochondrial electron transport chain on the cytochrome c oxidase activity and on the cardiolipin content in bovine submitochondrial particles. FEBS Lett. 466: 323-326, 2000.
-
(2000)
FEBS Lett.
, vol.466
, pp. 323-326
-
-
Paradies, G.1
Petrosillo, G.2
Pistolese, M.3
Ruggiero, F.M.4
-
46
-
-
0032513135
-
Peroxidative damage to cardiac mitochondria: Cytochrome oxidase and cardiolipin alterations
-
Paradies, G., Ruggiero, F.M., Petrosillo, G. and Quagliariello, E. Peroxidative damage to cardiac mitochondria: cytochrome oxidase and cardiolipin alterations. FEBS Lett. 424: 155-158, 1998.
-
(1998)
FEBS Lett.
, vol.424
, pp. 155-158
-
-
Paradies, G.1
Ruggiero, F.M.2
Petrosillo, G.3
Quagliariello, E.4
-
47
-
-
0033595780
-
Loss of molecular interaction between cytochrome c and cardiolipin due to lipid peroxidation
-
Shidoji, Y., Hayashi, K., Komura, S., Ohishi, N. and Yagi, K. Loss of molecular interaction between cytochrome c and cardiolipin due to lipid peroxidation. Biochem. Biophys. Res. Commun. 264: 343-347, 1999.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.264
, pp. 343-347
-
-
Shidoji, Y.1
Hayashi, K.2
Komura, S.3
Ohishi, N.4
Yagi, K.5
-
48
-
-
0034306791
-
Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis
-
Nomura, K., Imai, H., Koumura, T., Kobayashi, T. and Nakagawa, Y. Mitochondrial phospholipid hydroperoxide glutathione peroxidase inhibits the release of cytochrome c from mitochondria by suppressing the peroxidation of cardiolipin in hypoglycaemia-induced apoptosis. Biochem. J. 351: 183-193, 2000.
-
(2000)
Biochem. J.
, vol.351
, pp. 183-193
-
-
Nomura, K.1
Imai, H.2
Koumura, T.3
Kobayashi, T.4
Nakagawa, Y.5
-
49
-
-
0030881686
-
Oxidative damage during aging targets mitochondrial aconitase
-
Yan, L.J., Levine, R.L. and Sohal, R.S. Oxidative damage during aging targets mitochondrial aconitase. Proc. Natl. Acad. Sci. USA 94: 11168-11172, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11168-11172
-
-
Yan, L.J.1
Levine, R.L.2
Sohal, R.S.3
-
50
-
-
0032573066
-
Mitochondrial adenine nucleotide translocase is modified oxidatively during aging
-
Yan, L.J. and Sohal, R.S. Mitochondrial adenine nucleotide translocase is modified oxidatively during aging. Proc. Natl. Acad. Sci. USA 95: 12896-12901, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12896-12901
-
-
Yan, L.J.1
Sohal, R.S.2
-
51
-
-
0030897739
-
Genetic and functional changes in mitochondria associated with aging
-
Ozawa, T. Genetic and functional changes in mitochondria associated with aging. Physiol. Rev. 77: 425-464, 1997.
-
(1997)
Physiol. Rev.
, vol.77
, pp. 425-464
-
-
Ozawa, T.1
-
52
-
-
0034663641
-
Mitochondrial bioenergetics in aging
-
Lenaz, G., D'Aurelio, M., Pich, M.M., Genova, M.L., Ventura, B., Bovina, C., Formiggini, G. and Castelli, G.P. Mitochondrial bioenergetics in aging. Biochim. Biophys. Acta 1459: 397-404, 2000.
-
(2000)
Biochim. Biophys. Acta
, vol.1459
, pp. 397-404
-
-
Lenaz, G.1
D'Aurelio, M.2
Pich, M.M.3
Genova, M.L.4
Ventura, B.5
Bovina, C.6
Formiggini, G.7
Castelli, G.P.8
-
53
-
-
0024980878
-
Liver mitochondrial respiratory functions decline with age
-
Yen, T.C., Chen, Y.S., King, K.L., Yeh, S.H. and Wei, Y.H. Liver mitochondrial respiratory functions decline with age. Biochem. Biophys. Res. Commun. 165: 994-1003, 1989.
-
(1989)
Biochem. Biophys. Res. Commun.
, vol.165
, pp. 994-1003
-
-
Yen, T.C.1
Chen, Y.S.2
King, K.L.3
Yeh, S.H.4
Wei, Y.H.5
-
54
-
-
0026746336
-
Mitochondrial DNA alterations as ageing-associated molecular events
-
Wei, Y.H. Mitochondrial DNA alterations as ageing-associated molecular events. Mutat. Res. 275: 145-155, 1992.
-
(1992)
Mutat. Res.
, vol.275
, pp. 145-155
-
-
Wei, Y.H.1
-
55
-
-
0027198359
-
Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans
-
Zhang, C., Linnane, A.W. and Nagley, P. Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans. Biochem. Biophys. Res. Commun. 195: 1104-1110, 1993.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.195
, pp. 1104-1110
-
-
Zhang, C.1
Linnane, A.W.2
Nagley, P.3
-
56
-
-
0029741620
-
Tandem duplications and large-scale deletions of mitochondrial DNA are early molecular events of human aging process
-
Wei, Y.H., Pang, C.Y., You, B.J. and Lee, H.C. Tandem duplications and large-scale deletions of mitochondrial DNA are early molecular events of human aging process. Ann. N. Y. Acad. Sci. 786: 82-101, 1996.
-
(1996)
Ann. N. Y. Acad. Sci.
, vol.786
, pp. 82-101
-
-
Wei, Y.H.1
Pang, C.Y.2
You, B.J.3
Lee, H.C.4
-
57
-
-
0025741445
-
Ageing-associated 5 kb deletion in human liver mitochondrial DNA
-
Yen, T.C., Su, J.H., King, K.L. and Wei, Y.H. Ageing-associated 5 kb deletion in human liver mitochondrial DNA. Biochem. Biophys. Res. Commun. 178: 124-131, 1991.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.178
, pp. 124-131
-
-
Yen, T.C.1
Su, J.H.2
King, K.L.3
Wei, Y.H.4
-
58
-
-
0027963448
-
A specific 4,977 bp deletion of mitochondrial DNA in human ageing skin
-
Yang, J.H., Lee, H.C. and Wei, Y.H. A specific 4,977 bp deletion of mitochondrial DNA in human ageing skin. Arch. Dermatol Res. 286: 386-390, 1994.
-
(1994)
Arch. Dermatol Res.
, vol.286
, pp. 386-390
-
-
Yang, J.H.1
Lee, H.C.2
Wei, Y.H.3
-
59
-
-
0029919382
-
Age-related 4,977 bp deletion in human lung mitochondrial DNA
-
Fahn, H.J., Wang, L.S., Hsieh, R.H., Chang, S.C., Kao, S.H., Huang, M.H. and Wei, Y.H. Age-related 4,977 bp deletion in human lung mitochondrial DNA. Am. J. Respir. Crit. Care Med. 154: 1141-1145, 1996.
-
(1996)
Am. J. Respir. Crit. Care Med.
, vol.154
, pp. 1141-1145
-
-
Fahn, H.J.1
Wang, L.S.2
Hsieh, R.H.3
Chang, S.C.4
Kao, S.H.5
Huang, M.H.6
Wei, Y.H.7
-
60
-
-
0027476395
-
The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages
-
Münscher, C., Rieger, T. Müller-Höcker, J. and Kadenbach, B. The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages. FEBS Lett. 317:27-30, 1993.
-
(1993)
FEBS Lett.
, vol.317
, pp. 27-30
-
-
Münscher, C.1
Rieger, T.2
Müller-Höcker, J.3
Kadenbach, B.4
-
61
-
-
0029741431
-
Evidence that specific mtDNA point mutations may not accumulate in skeletal muscle during normal human aging
-
Pallotti, F., Chen, X., Bonilla, E. and Schon, E.A. Evidence that specific mtDNA point mutations may not accumulate in skeletal muscle during normal human aging. Am. J. Hum. Genet. 59: 591-602, 1996.
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 591-602
-
-
Pallotti, F.1
Chen, X.2
Bonilla, E.3
Schon, E.A.4
-
62
-
-
0028349234
-
Differential accumulations of 4,977 bp deletion in mitochondrial DNA of various tissues in human ageing
-
Lee, H.C., Pang, C.Y., Hsu, H.S. and Wei, Y.H. Differential accumulations of 4,977 bp deletion in mitochondrial DNA of various tissues in human ageing. Biochim. Biophys. Acta 1226: 37-43, 1994.
-
(1994)
Biochim. Biophys. Acta
, vol.1226
, pp. 37-43
-
-
Lee, H.C.1
Pang, C.Y.2
Hsu, H.S.3
Wei, Y.H.4
-
63
-
-
0026469073
-
Analysis of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: Effect of ageing
-
Cooper, J.M., Mann, V.M. and Schapira, A.H.V. Analysis of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing. J. Neurol. Sci. 113: 91-98, 1992.
-
(1992)
J. Neurol. Sci.
, vol.113
, pp. 91-98
-
-
Cooper, J.M.1
Mann, V.M.2
Schapira, A.H.V.3
-
64
-
-
0033060033
-
Mitochondrial DNA-all things bad?
-
Lightowlers, R.N., Jacobs, H.T. and Kajander, O.A. Mitochondrial DNA-all things bad? Trends Genet. 15: 91-93, 1999.
-
(1999)
Trends Genet.
, vol.15
, pp. 91-93
-
-
Lightowlers, R.N.1
Jacobs, H.T.2
Kajander, O.A.3
-
65
-
-
0032511842
-
An age-associated correlation between cellular bioenergy decline and mtDNA rearrangements in human skeletal muscle
-
Kopsidas, G., Kovalenko, S.A., Kelso, J.M. and Linnane, A.W. An age-associated correlation between cellular bioenergy decline and mtDNA rearrangements in human skeletal muscle. Mutat. Res. 421: 27-36, 1998.
-
(1998)
Mutat. Res.
, vol.421
, pp. 27-36
-
-
Kopsidas, G.1
Kovalenko, S.A.2
Kelso, J.M.3
Linnane, A.W.4
-
66
-
-
0033595684
-
Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication
-
Michikawa, Y., Mazzucchelli, F., Bresolin, N., Scarlato, G. and Attardi, G. Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication. Science 286: 774-779, 1999.
-
(1999)
Science
, vol.286
, pp. 774-779
-
-
Michikawa, Y.1
Mazzucchelli, F.2
Bresolin, N.3
Scarlato, G.4
Attardi, G.5
-
67
-
-
0027513262
-
Age-associated damage in mitochondrial DNA in human hearts
-
Hayakawa, M., Sugiyama, S., Hattori, K., Takasawa, M. and Ozawa, T. Age-associated damage in mitochondrial DNA in human hearts. Mol. Cell. Biochem. 119: 95-103, 1993.
-
(1993)
Mol. Cell. Biochem.
, vol.119
, pp. 95-103
-
-
Hayakawa, M.1
Sugiyama, S.2
Hattori, K.3
Takasawa, M.4
Ozawa, T.5
-
68
-
-
0032427717
-
The age-associated decrease in the amount of amplifiable full-length mitochondrial DNA in human skeletal muscle
-
Kovalenko, S.A., Kopsidas, G., Islam, M.M. Heffernan, D., Fitzpatrick, J., Caragounis, A., Gingold, E. and Linnane, A.W. The age-associated decrease in the amount of amplifiable full-length mitochondrial DNA in human skeletal muscle. Biochem. Mol. Biol. Int. 46: 1233-1241, 1998.
-
(1998)
Biochem. Mol. Biol. Int.
, vol.46
, pp. 1233-1241
-
-
Kovalenko, S.A.1
Kopsidas, G.2
Islam, M.M.3
Heffernan, D.4
Fitzpatrick, J.5
Caragounis, A.6
Gingold, E.7
Linnane, A.W.8
-
69
-
-
0030581498
-
Mitochondrial oxidative phosphorylation changes in the life span: Molecular aspects and physiopathological implications
-
Papa, S. Mitochondrial oxidative phosphorylation changes in the life span: Molecular aspects and physiopathological implications. Biochim. Biophys. Acta 1276: 87-105, 1996.
-
(1996)
Biochim. Biophys. Acta
, vol.1276
, pp. 87-105
-
-
Papa, S.1
-
70
-
-
0024366601
-
Cytochrome c oxidase deficient cardiomyocytes in the human heart: An age-related phenomenon. A histochemical ultracytochemical study
-
Müller-Höcker, J. Cytochrome c oxidase deficient cardiomyocytes in the human heart: an age-related phenomenon. A histochemical ultracytochemical study. Am. J. Pathol. 134: 1167-1173, 1989.
-
(1989)
Am. J. Pathol.
, vol.134
, pp. 1167-1173
-
-
Müller-Höcker, J.1
-
71
-
-
0025673968
-
Cytochrome c oxidase deficient fibers in the limb muscle and diaphragm of man without muscular disease: An age-related alteration
-
Müller-Höcker, J. Cytochrome c oxidase deficient fibers in the limb muscle and diaphragm of man without muscular disease: an age-related alteration. J. Neurol. Sci. 100: 14-21, 1990.
-
(1990)
J. Neurol. Sci.
, vol.100
, pp. 14-21
-
-
Müller-Höcker, J.1
-
72
-
-
0031885843
-
Role of mitochondrial DNA mutations in human aging: Implications for the central nervous system and muscle
-
Brierley, E.J., Johnson, M.A., Lightowlers, R.N., James, O.F. and Turnbull, D.M. Role of mitochondrial DNA mutations in human aging: implications for the central nervous system and muscle. Ann. Neurol. 43: 217-223, 1998.
-
(1998)
Ann. Neurol.
, vol.43
, pp. 217-223
-
-
Brierley, E.J.1
Johnson, M.A.2
Lightowlers, R.N.3
James, O.F.4
Turnbull, D.M.5
-
73
-
-
0028109191
-
Superoxide dismutase, aging, and degenerative disease
-
Warner, H.R. Superoxide dismutase, aging, and degenerative disease. Free Radic. Biol. Med. 17: 249-258, 1994.
-
(1994)
Free Radic. Biol. Med.
, vol.17
, pp. 249-258
-
-
Warner, H.R.1
-
74
-
-
1542563727
-
The rate of free radical production as a determinant of the rate of aging: Evidence from the comparative approach
-
Perez-Campo, R., Lopez-Torres, M., Cadenas, S., Rojas, C. and Barja, G. The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach. J. Comp. Physiol. 168: 149-158, 1998.
-
(1998)
J. Comp. Physiol.
, vol.168
, pp. 149-158
-
-
Perez-Campo, R.1
Lopez-Torres, M.2
Cadenas, S.3
Rojas, C.4
Barja, G.5
-
75
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel, T. and Holbrook, N.J. Oxidants, oxidative stress and the biology of ageing. Nature 408: 239-247, 2000.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
76
-
-
0028220114
-
Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
-
Orr, W.C. and Sohal, R.S. Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263: 1128-1130, 1994.
-
(1994)
Science
, vol.263
, pp. 1128-1130
-
-
Orr, W.C.1
Sohal, R.S.2
-
77
-
-
0027293919
-
Effects of Cu,Zn superoxide dismutase overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster
-
Orr, W.C. and Sohal, R.S. Effects of Cu,Zn superoxide dismutase overexpression on life span and resistance to oxidative stress in transgenic Drosophila melanogaster. Arch. Biochem. Biophys. 301: 34-40, 1993.
-
(1993)
Arch. Biochem. Biophys.
, vol.301
, pp. 34-40
-
-
Orr, W.C.1
Sohal, R.S.2
-
78
-
-
0034006162
-
Ubiquitous overexpression of Cu,Zn superoxide dismutase does not extend life span in mice
-
Huang, T.T., Carlson, E.J., Gillespie, A.M., Shi, Y. and Epstein, C. J. Ubiquitous overexpression of Cu,Zn superoxide dismutase does not extend life span in mice. J. Gerontol. Biol. Sci. A55: B5-B9, 2000.
-
(2000)
J. Gerontol. Biol. Sci.
, vol.A55
-
-
Huang, T.T.1
Carlson, E.J.2
Gillespie, A.M.3
Shi, Y.4
Epstein, C.J.5
-
79
-
-
0032820186
-
Age-dependent changes of antioxidant activities and markers of free radical damage in human skeletal muscles
-
Pansarasa, O., Bertorelli, L., Vecchiet, J., Felzani, G. and Marzatico, F. Age-dependent changes of antioxidant activities and markers of free radical damage in human skeletal muscles. Free Radic. Biol. Med. 27: 617-622, 1999.
-
(1999)
Free Radic. Biol. Med.
, vol.27
, pp. 617-622
-
-
Pansarasa, O.1
Bertorelli, L.2
Vecchiet, J.3
Felzani, G.4
Marzatico, F.5
-
80
-
-
0032244778
-
Expression and developmental profile of antioxidant enzymes in human lung and liver
-
Asikainen, T.M., Raivio, K.O., Saksela, M. and Kinnula, V.L. Expression and developmental profile of antioxidant enzymes in human lung and liver. Am. J. Respir. Cell Mol. Biol. 19: 942-949, 1998.
-
(1998)
Am. J. Respir. Cell Mol. Biol.
, vol.19
, pp. 942-949
-
-
Asikainen, T.M.1
Raivio, K.O.2
Saksela, M.3
Kinnula, V.L.4
-
81
-
-
0032820186
-
Age-dependent changes of antioxidant enzyme activities and markers of free radical damage in human skeletal muscle
-
Pansarsa, O., Bertorelli, L., Vecchiet, J., Felzani, G. and Marzatico, F. Age-dependent changes of antioxidant enzyme activities and markers of free radical damage in human skeletal muscle. Free Radic. Biol. Med. 21: 617-622, 1999.
-
(1999)
Free Radic. Biol. Med.
, vol.21
, pp. 617-622
-
-
Pansarsa, O.1
Bertorelli, L.2
Vecchiet, J.3
Felzani, G.4
Marzatico, F.5
-
82
-
-
0033772773
-
Age-associated changes of superoxide dismutase and catalase activities in the rat brain
-
Tsay, H.J., Wang, P., Wang, S. L. and Ku, H.H. Age-associated changes of superoxide dismutase and catalase activities in the rat brain. J. Biomed. Sci. 7: 466-474, 2000.
-
(2000)
J. Biomed. Sci.
, vol.7
, pp. 466-474
-
-
Tsay, H.J.1
Wang, P.2
Wang, S.L.3
Ku, H.H.4
-
83
-
-
0032747797
-
Aging: Is oxidative stress a marker or is it causal?
-
Fukagawa, N.K. Aging: Is oxidative stress a marker or is it causal? Proc. Soc. Exp. Biol. Med. 222: 293-298, 1999.
-
(1999)
Proc. Soc. Exp. Biol. Med.
, vol.222
, pp. 293-298
-
-
Fukagawa, N.K.1
-
84
-
-
0041187446
-
Enhanced oxidative stress and unbalanced expression of free radical scavenging enzymes in human aging and mitochondrial disease
-
Hoshi, T. et al., eds., Shizuoka Research Institute, Shizuoka, Japan
-
Wei, Y.H. Enhanced oxidative stress and unbalanced expression of free radical scavenging enzymes in human aging and mitochondrial disease. In: Proceedings of the 5th Shizuoka Forum on Health and Longevity (Hoshi, T. et al., eds.), pp. 32-41, Shizuoka Research Institute, Shizuoka, Japan, 2001.
-
(2001)
Proceedings of the 5th Shizuoka Forum on Health and Longevity
, pp. 32-41
-
-
Wei, Y.H.1
-
85
-
-
0028805219
-
Superoxide dismutases of muscle in mitochondrial encephalomyopathies
-
Ohkoshi, N., Mizusawa, H., Shiraiwa, N., Shoji, S., Harada, K. and Yoshizawa, K. Superoxide dismutases of muscle in mitochondrial encephalomyopathies. Muscle & Nerve 18: 1265-1271, 1995.
-
(1995)
Muscle & Nerve
, vol.18
, pp. 1265-1271
-
-
Ohkoshi, N.1
Mizusawa, H.2
Shiraiwa, N.3
Shoji, S.4
Harada, K.5
Yoshizawa, K.6
-
86
-
-
0030200795
-
Oxidative damage to skeletal muscle DNA from patients with mitochondrial encephalomyopathies
-
Mitsui, T., Kawai, H., Nagasawa, M., Kunishige, M., Akaike, M., Kimura, Y. and Saito, S. Oxidative damage to skeletal muscle DNA from patients with mitochondrial encephalomyopathies. J. Neurol. Sci. 139: 111-116, 1996.
-
(1996)
J. Neurol. Sci.
, vol.139
, pp. 111-116
-
-
Mitsui, T.1
Kawai, H.2
Nagasawa, M.3
Kunishige, M.4
Akaike, M.5
Kimura, Y.6
Saito, S.7
-
87
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
Li, Y., Huang, T.T. Carlson, E.J., Melvo, S., Ursell, P.C., Olson, J. L., Noble, L.J., Yoshimura, M.P., Berge, C., Chan, P.H., Wallace, D.C. and Epstein, C.J. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nature Genet. 11: 376-381, 1995.
-
(1995)
Nature Genet.
, vol.11
, pp. 376-381
-
-
Li, Y.1
Huang, T.T.2
Carlson, E.J.3
Melvo, S.4
Ursell, P.C.5
Olson, J.L.6
Noble, L.J.7
Yoshimura, M.P.8
Berge, C.9
Chan, P.H.10
Wallace, D.C.11
Epstein, C.J.12
-
88
-
-
0032885238
-
Mitochondrial myopathies and encephalomyopathies
-
Schapira, A.H.V. and Cock, H.R. Mitochondrial myopathies and encephalomyopathies. Eur. J. Clin. Invest. 29: 886-898, 1999.
-
(1999)
Eur. J. Clin. Invest.
, vol.29
, pp. 886-898
-
-
Schapira, A.H.V.1
Cock, H.R.2
-
89
-
-
0028145185
-
Free radical, lipid peroxide and antioxidant in mitochondrial encephalomyopathy
-
Ihara, Y., Hayabara, T., Namba, R., Nobukuni, K. and Mon, A. Free radical, lipid peroxide and antioxidant in mitochondrial encephalomyopathy. Clin. Neurol. 34: 593-595, 1994.
-
(1994)
Clin. Neurol.
, vol.34
, pp. 593-595
-
-
Ihara, Y.1
Hayabara, T.2
Namba, R.3
Nobukuni, K.4
Mon, A.5
-
90
-
-
0034700807
-
Mitochondrial respiratory chain disorders 1: Mitochondrial DNA defects
-
Leonard, J.V. and Schapira, A.H.V. Mitochondrial respiratory chain disorders 1: mitochondrial DNA defects. Lancet 355: 299-304, 2000.
-
(2000)
Lancet
, vol.355
, pp. 299-304
-
-
Leonard, J.V.1
Schapira, A.H.V.2
-
91
-
-
0033990284
-
Increased activities of antioxidant enzymes and decreased ATP concentration in cultured myoblasts with the 3243 A→G mutation in mitochondrial DNA
-
Rusanen, H., Majamaa, K. and Hassinen, I.E. Increased activities of antioxidant enzymes and decreased ATP concentration in cultured myoblasts with the 3243 A→G mutation in mitochondrial DNA. Biochim. Biophys. Acta 1500: 10-16, 2000.
-
(2000)
Biochim. Biophys. Acta
, vol.1500
, pp. 10-16
-
-
Rusanen, H.1
Majamaa, K.2
Hassinen, I.E.3
-
92
-
-
0033522924
-
Titrating the effects of mitochondrial complex I impairment in the cell physiology
-
Barrientos, A. and Moraes, C.T. Titrating the effects of mitochondrial complex I impairment in the cell physiology. J. Biol. Chem. 274: 16188-16197, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16188-16197
-
-
Barrientos, A.1
Moraes, C.T.2
-
94
-
-
0030711001
-
Mitochondrial respiratory chain deficiency leads to overexpression of antioxidant enzymes
-
Brambilla, L., Cairo, G., Sestili, P., O'Donnel, V., Azzi, A. and Cantoni, O. Mitochondrial respiratory chain deficiency leads to overexpression of antioxidant enzymes. FEBS Lett. 418: 247-250, 1997.
-
(1997)
FEBS Lett.
, vol.418
, pp. 247-250
-
-
Brambilla, L.1
Cairo, G.2
Sestili, P.3
O'Donnel, V.4
Azzi, A.5
Cantoni, O.6
-
95
-
-
0028345161
-
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells
-
Chen, Q. and Ames, B.N. Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc. Natl. Acad. Sci. USA 91: 4130-4134, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4130-4134
-
-
Chen, Q.1
Ames, B.N.2
-
96
-
-
0028012335
-
Glutathione peroxidase compensates for the hypersensitivity of Cu,Zn-superoxide dismutase overproducers to oxidant stress
-
Amstad, P., Moret, R. and Cerutti, P. Glutathione peroxidase compensates for the hypersensitivity of Cu,Zn-superoxide dismutase overproducers to oxidant stress. J. Biol. Chem. 269: 1606-1609, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1606-1609
-
-
Amstad, P.1
Moret, R.2
Cerutti, P.3
-
97
-
-
0023841357
-
Expression of transfected human Cu,Zn superoxide dismutase gene in mouse L cells and NS20Y neuroblastoma cells induces enhancement of glutathione peroxidase activity
-
Ceballos, I., Delabar, J.M., Nicole, A., Lynch, R.E., Hallewell, R. A., Kamoun, P. and Sinet, P.M. Expression of transfected human Cu,Zn superoxide dismutase gene in mouse L cells and NS20Y neuroblastoma cells induces enhancement of glutathione peroxidase activity. Biochim. Biophys. Acta 949: 58-64, 1988.
-
(1988)
Biochim. Biophys. Acta
, vol.949
, pp. 58-64
-
-
Ceballos, I.1
Delabar, J.M.2
Nicole, A.3
Lynch, R.E.4
Hallewell, R.A.5
Kamoun, P.6
Sinet, P.M.7
-
98
-
-
0030068056
-
Elevation in the ratio of Cu,Zn-superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide
-
de Haan, J. B., Cristiano, F., Iannello, R., Bladier, C., Kelner, M. J. and Kola, I. Elevation in the ratio of Cu,Zn-superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide. Hum. Mol. Genet 5: 283-292, 1996.
-
(1996)
Hum. Mol. Genet
, vol.5
, pp. 283-292
-
-
De Haan, J.B.1
Cristiano, F.2
Iannello, R.3
Bladier, C.4
Kelner, M.J.5
Kola, I.6
-
99
-
-
0031966914
-
Inhibition of cell growth in NIH/3T3 fibroblasts by overexpression of manganese superoxide dismutase: Mechanistic studies
-
Li, N., Oberley, T.D., Oberley, L.W. and Zhong, W. Inhibition of cell growth in NIH/3T3 fibroblasts by overexpression of manganese superoxide dismutase: Mechanistic studies. J. Cell. Physiol. 175: 359-369, 1998.
-
(1998)
J. Cell. Physiol.
, vol.175
, pp. 359-369
-
-
Li, N.1
Oberley, T.D.2
Oberley, L.W.3
Zhong, W.4
-
100
-
-
0033520497
-
Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major matrix-degrading metalloprotease-1
-
Wenk, J., Brenneisen, P., Wlaschek, M., Poswig, A., Brivibas, K., Oberley, T.D. and Scharffetter-Kochanek, K. Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major matrix-degrading metalloprotease-1. J. Biol. Chem. 274: 25869-25876, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25869-25876
-
-
Wenk, J.1
Brenneisen, P.2
Wlaschek, M.3
Poswig, A.4
Brivibas, K.5
Oberley, T.D.6
Scharffetter-Kochanek, K.7
-
101
-
-
0031940986
-
A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase
-
Melov, S., Coskun, P., Patel, M., Tuinstra, R., Cottrell, B., Jun, A. S., Zastawny, T.H., Dizdaroglu, M., Goodman, S.I., Huang, T.T., Miziorko, H., Epstein, C.J. and Wallace, D.C. A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase. Nature Genet. 18: 159-163, 1998.
-
(1998)
Nature Genet.
, vol.18
, pp. 159-163
-
-
Melov, S.1
Coskun, P.2
Patel, M.3
Tuinstra, R.4
Cottrell, B.5
Jun, A.S.6
Zastawny, T.H.7
Dizdaroglu, M.8
Goodman, S.I.9
Huang, T.T.10
Miziorko, H.11
Epstein, C.J.12
Wallace, D.C.13
-
102
-
-
13044285432
-
Mitochondrial disease in superoxide dismutase 2 mutant mice
-
USA
-
Melov, S., Coskun, P., Patel, M., Tuinstra, R., Cottrell, B., Jun, A. S., Zastawny, T. H., Dizdaroglu, M., Goodman, S.I., Huang, T.T., Miziorko, H., Epstein, C.J. and Wallace, D.C. Mitochondrial disease in superoxide dismutase 2 mutant mice. Proc. Natl. Acad. Sci. USA 96: 846-851, 1999.
-
(1999)
Proc. Natl. Acad. Sci.
, vol.96
, pp. 846-851
-
-
Melov, S.1
Coskun, P.2
Patel, M.3
Tuinstra, R.4
Cottrell, B.5
Jun, A.S.6
Zastawny, T.H.7
Dizdaroglu, M.8
Goodman, S.I.9
Huang, T.T.10
Miziorko, H.11
Epstein, C.J.12
Wallace, D.C.13
-
103
-
-
0032561328
-
Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice
-
Williams, M.D., van Remmen, H., Conrad, C.C., Huang, T.T., Epstein, C.J. and Richardson, A. Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice. J. Biol. Chem. 273: 28510-28515, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28510-28515
-
-
Williams, M.D.1
Van Remmen, H.2
Conrad, C.C.3
Huang, T.T.4
Epstein, C.J.5
Richardson, A.6
-
104
-
-
0034062554
-
Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene
-
Esposito, L.A., Kokoszka, J.E., Waymire, K.G., Cottrell, B., MacGregor, G.R., and Wallace, D.C. Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene. Free Radic. Biol Med. 28: 754-766, 2000.
-
(2000)
Free Radic. Biol Med.
, vol.28
, pp. 754-766
-
-
Esposito, L.A.1
Kokoszka, J.E.2
Waymire, K.G.3
Cottrell, B.4
MacGregor, G.R.5
Wallace, D.C.6
-
105
-
-
0034284973
-
Extension of life-span with superoxide dismutase/ catalase mimetics
-
Melov, S., Ravenscroft, J., Malik, S., Gill, M.S., Walker, D.W., Clayton, P.E., Wallace, D.C., Malfroy, B., Doctrow, S.R. and Lithgow, G.J. Extension of life-span with superoxide dismutase/ catalase mimetics. Science 289: 1567-1569, 2000.
-
(2000)
Science
, vol.289
, pp. 1567-1569
-
-
Melov, S.1
Ravenscroft, J.2
Malik, S.3
Gill, M.S.4
Walker, D.W.5
Clayton, P.E.6
Wallace, D.C.7
Malfroy, B.8
Doctrow, S.R.9
Lithgow, G.J.10
-
106
-
-
0033972463
-
Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals
-
Barja, G. and Herrero, A. Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals. FASEB J. 14: 312-318, 2000.
-
(2000)
FASEB J.
, vol.14
, pp. 312-318
-
-
Barja, G.1
Herrero, A.2
|