Oxidative damage elicited by imbalance of free radical scavenging enzymes is associated with large-scale mtDNA deletions in aging human skin

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 423, Issue 1-2, 1999, Pages 11-21

  Lu, Ching You ^b   Lee, Hsin Chen ^b   Fahn, Huei Jyh ^b   Wei, Yau Huei ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NONE

Author keywords

8 hydroxy 2' deoxyguanosine; Free radical scavenging enzyme; Lipid peroxidation; Mitochondrial DNA mutation; Oxidative stress

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; ENZYME; FREE RADICAL; GLUTATHIONE PEROXIDASE; LIPID PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; SCAVENGER;

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE DELETION; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; OXIDATIVE STRESS; PRIORITY JOURNAL; SCHOOL CHILD; SKIN; SKIN FIBROBLAST;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CHILD; DEOXYGUANOSINE; DNA, MITOCHONDRIAL; FIBROBLASTS; FREE RADICAL SCAVENGERS; HUMANS; LIPID PEROXIDES; MIDDLE AGED; MUTATION; OXIDATIVE STRESS; SEQUENCE DELETION; SKIN; SKIN AGING;

EID: 0002026429     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00220-6     Document Type: Article

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