Physiology of EAG K+ channels

Journal of Membrane Biology

Volumn 182, Issue 1, 2001, Pages 1-15

  Bauer, C K ^a   Schwarz, J R ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; POTASSIUM CHANNEL; PROTEIN SUBUNIT;

CHANNEL GATING; DROSOPHILA MELANOGASTER; MEMBRANE ELECTROPHYSIOLOGY; MEMBRANE STEADY POTENTIAL; NONHUMAN; PHENOTYPE; POTASSIUM CURRENT; PROTEIN DOMAIN; PROTEIN EXPRESSION; REVIEW;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0035399465     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-001-0031-3     Document Type: Review

References (128)

1. Kr potassium channels with HERG and is associated with cardiac arrhythmia
2. + currents in opossum esophageal circular smooth muscle
3. Integrin-mediated neurite outgrowth in neuroblastoma cells depends on the activation of potassium channels
4. + current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells
5. + inwardly rectifying current: Relevance to neuritogenesis
6. HERG- and IRK-like inward rectifier currents are sequentially expressed during neuronal development of neural crest cells and their derivatives
7. 3 anterior pituitary cells
8. + channel gating by activation of a G protein-coupled receptor and protein kinase C
9. 3 pituitary cells
10. + current and its modulation by thyrotrophin-releasing hormone in giant clonal rat anterior pituitary cells
11. Different G proteins are involved in the biphasic response of clonal rat pituitary cells to thyrotropin-releasing hormone
12. RERG is a molecular correlate of the inward-rectifying K current in clonal rat pituitary cells
13. + current in clonal rat pituitary cells and its modulation by thyrotrophin-releasing hormone
14. + current in prolactin secretion from rat lactotrophs
15. + channel that accelerates the rod response to dim light
16. Kr and trafficking in long QT syndrome
17. + current highly conserved in tumors of different histogenesis: A selective advantage for cancer cells?
18. h-eag, contributes to the hyperpolarization of human fusion-competent myoblasts
19. M currents
20. 2+ and modulated by cAMP
21. Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopus oocytes
22. Cytoskeletal interactions determine the electrophysiological properties of human EAG potassium channels
23. Voltage-gated potassium channel genes
24. Long QT syndrome-associated mutations in the per-arnt-sim (PAS) domain of HERG potassium channels accelerate channel deactivation
25. + channel subunit interaction in frog oocytes depends on level and time of expression
26. + channels: Spike-frequency adaptation
27. + channels involved in long QT syndromes, are targets for calcium channel blockers
28. A quantitative description of the E-4031-sensitive repolarization current in rabbit ventricular myocytes
29. Electrophysiology of anterior pituitary cells
30. An inactivating inward-rectifying K current present in prolactin cells from the pituitary of lactating rats
31. + channel by dual pathways
32. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
33. Molecular characterization of eag: A gene affecting potassium channels in Drosophila melanogaster
34. + channel gene ether a go-go is required for the transduction of a subset of odorants in adult Drosophila melanogaster
35. Blockade of HERG and Kv1.5 by ketoconazole
36. EGL-36 Shaw channels regulate C. elegans egg-laying muscle activity
37. Do glia have heart? Expression and functional role for ether-a-go-go currents in hippocampal astrocytes
38. + channel genes
39. Effects of outer mouth mutations on hERG channel function: A comparison with similar mutations in the Shaker channel
40. + channel in rat F-11 DRG cell line: Pharmacological identification and biophysical characterization
41. + current in rod inner segments
42. + channels in Drosophila and mammals
43. Neurogenetic analysis of potassium currents in Drosophila: Synergistic effects on neuromuscular transmission in double mutants
44. Sildenafil (Viagra) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current
45. + channels isolated from Centruroides noxius scorpion venom
46. Time course and voltage dependence of expressed HERG current compared with native "rapid" delayed rectifier K current during the ventricular action potential
47. Ks in guinea-pig isolated ventricular myocytes
48. Kr, through a reduction in C-type inactivation in guinea-pig ventricular myocytes
49. Transfer of rapid inactivation and sensitivity to the class III antiarrhythmic drug E-4031 from HERG to M-eag channels
50. 2+
51. + channels
52. + channel in rabbit sinoatrial node cells
53. Behavioral defects in C. elegans egl-36 mutants result from potassium channels shifted in voltage-dependence of activation
54. + channel splice variant common in human heart lacks a C-terminal domain required for expression of rapidly activating delayed rectifier current
55. Potassium channel ether à go-go mRNA expression in the spiral ligament of the rat
56. + channel in mouse and human hearts
57. + current and of hyperpolarization in human myoblast fusion
58. Activation and inactivation kinetics of an E-4031-sensitive current from single ferret atrial myocytes
59. + current
60. Functional expression of a rat homologue of the voltage gated ether á go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart
61. Cloning and functional expression of rat eag2, a new member of the ether-à-go-go family of potassium channels and comparison of its distribution with that of eagl
62. Kr
63. Characterization of an eag-like potassium channel in human neuroblastoma cells
64. Identification of ether à go-go and calcium-activated potassium channels in human melanoma cells
65. + channel by the gastrointestinal prokinetic agent cisapride
66. Crystal structure and functional analysis of the HERG potassium channel N terminus: A eukaryotic PAS domain
67. Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion
68. HERG-like potassium current regulates the resting the resting membrane potential in glomus cells of the rabbit carotid body
69. + channels
70. + channels
71. Biological sensors: More than one way to sense oxygen
72. Purification of an EH domain-binding protein from rat brain that modulates the gating of the rat ether-à-go-go channel
73. Kr channels
74. Molecular biology of voltage-dependent potassium channels
75. Potassium currents expressed from Drosophila and mouse eag cDNAs in Xenopus oocytes
76. Sulfonylureas blockade of neural and cardiac HERG channels
77. + channel with a unique pattern of expression in the cerebral cortex
78. +-channel dysfunction in an inherited cardiac arrhythmia
79. Kr potassium channel
80. + current
81. Role of delayed rectifier potassium channels in cardiac repolarization and arrhythmias
82. The erg-like potassium current in rat lactotrophs
83. + currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade
84. Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel
85. 2+/calmodulin
86. + channels
87. A constitutively open potassium channel formed by KCNQ1 and KCNE3
88. + current: Functions of a strange inward rectifier
89. Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic ganglia
90. Identification of two nervous system-specific members of the erg potassium channel gene family
91. Conductance and kinetics of delayed rectifier potassium channels in nodal cells of the rabbit heart
92. The inward rectification mechanism of the HERG cardiac potassium channel
93. High affinity open channel block by dofetilide of HERG expressed in a human cell line
94. + channel
95. Kr channel
96. K block and lack of reverse use dependence in cat ventricular myocytes
97. Elevation of intracellular calcium by muscarinic receptor activation induces a block of voltage-activated rat ether-à-go-go channels in a stably transfected cell line
98. The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes
99. Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole
100. + channels by reactive oxygen species
101. Drug-induced torsade de pointes: From molecular biology to bedside
102. 2+ regulates activation of rat eag potassium channel
103. Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A
104. Inhibition of HERG potassium channels by the antimalariant agent halofantrine
105. + channel polypeptide is encoded by the seizure locus
106. + channel
107. HERG, a human inward rectifier in the voltage-gated potassium channel family
108. Effects of delayed rectifier current blockage by E-4031 on impulse generation in single sinuatrial nodal myocytes of the rabbit
109. + channel gating
110. A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes
111. + channels
112. Regulation of deactivation by an amino terminal domain in Human ether-à-go-go-related gene potassium channels
113. A distinct potassium channel polypeptide encoded by the Drosophila eag locus
114. A family of potassium channel genes related to eag in Drosophila and mammals
115. Eight potassium channel families revealed by the C. elegans genome project
116. 6 cells)
117. + channel by imipramine rescues egl-2 excitation defects in Caenorhabditis elegans
118. Interaction of the K channel β subunit, hyperkinetic, with eag family members
119. Erg1, erg2 and erg3 K channel subunits are able to form heteromultimers
120. Potassium currents in Drosophila: Different components affected by mutations of two genes
121. 6 cells and rat pituitary
122. + channel, erg
123. + current
124. Ionic currents during sustained pacemaker activity in rabbit sino-atrial myocytes
125. + currents in Drosophila muscle by mutations in eag
126. + channels
127. + channels in microglia
128. Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature