Eight potassium channel families revealed by the C. elegans genome project

Neuropharmacology

Volumn 35, Issue 7, 1996, Pages 805-829

  Wei, A ^a   Jegla, T ^a,b   Salkoff, L ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

C. elegans; Genome project; Potassium channel

Indexed keywords

POTASSIUM CHANNEL;

AMINO ACID SEQUENCE; ARTICLE; CAENORHABDITIS ELEGANS; GENOME; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN STRUCTURE;

EID: 0029861307     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/0028-3908(96)00126-8     Document Type: Article

References (131)

1. Adelman J.P., Shen K.Z., Kavanaugh M.P., Warren R.A., Wu Y.N., Lagrutta A., Bond C.T., North R.A. Calcium-activated potassium channels expressed from cloned complementary DNAs. Neuron. 9:1992;209-216.
2. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J. Molec. Biol. 215:1990;403-410.
3. Anderson J.A., Huprikar S.S., Kochian L.V., Lucas W.J. and Gaber R.F. (1992) Functional expression of a probable Arabidopis thaliana potassium channel in Saccharomyces cerevisiae. Proc. Natn. Acad. Sci. U.S.A. 89: 3736-3740.
4. Ashford M.L.J., Bond C.T., Blair T.A., Adelman J.P. Cloning and functional expression of a rat heart KATP channel. Nature. 370:1994;456-459.
5. Atkinson N.S., Robertson G.A., Ganetzky B. A component of calcium-activated potassium channels encoded by the Drosophila slo locus. Science. 253:1991;551-555.
6. Avery L., Raizen D., Lockery S. Electrophysiological methods. Meth. Cell Biol. 48:1995;251-269.
7. Baro D.J., Cole C.L., Zarrin A.R., Hughes S., Harris-Warrick R.M. Shab gene expression in identified neurons of the pyloric network in the lobster stomatogastric ganglion. Recept. Channels. 2:1994;193-205.
8. Baro D.J., Coniglio L.M., Cole C.C., Rodriguez H.E., Lubell J.K., Kim M.T., Harris-Warrick R.M. Lobster shal: Comparison with Drosophila shal and native potassium currents in identified neurons. J. Neurosci. 16:1996;1689-1701.
9. Baumann A., Frings S., Godde M., Seifert R., Kaupp U.B. Primary structure and functional expression of a Drosophila cyclic nucleotide-gated channel present in eyes and antennae. Eur. Molec. Biol. Org. J. 13:1994;5040-5050.
10. Baumann A., Grupe A., Ackermann A., Pongs O. Structure of the voltage-dependent potassium channel is highly conserved from Drosophila to vertebrate central nervous systems. Eur. Molec. Biol. Org. J. 7:1988;2457-2463.
11. Blumenthal T. Trans-splicing and polycistronic transcription in Caenorhabditis elegans. Trends Genet. 11:1995;132-136.
12. Bond C.T., Pessia M., Xia X.M., Lagrutta A., Kavanaugh M.P., Adelman J.P. Cloning and expression of a family of inward rectifier potassium channels. Recept. Channels. 2:1994;183-191.
13. Bredt D.S., Wang T.L., Cohen N.A., Guggino W.B., Snyder S.H. Cloning and expression of two brain-specific inwardly rectifying potassium channels. Proc. Natn. Acad. Sci. U.S.A. 92:1995;6753-6757.
14. Brenner S. The genetics of Caenorhabditis elegans. Genetics. 77:1974;71-94.
15. Butler A., Tsunoda S., McCobb D.P., Wei A., Salkoff L. MSlo, a complex mouse gene encoding `maxi' calcium-activated potassium channels. Science. 261:1993;221-224.
16. Butler A., Wei A., Baker K., Salkoff L. A family of putative potassium channel genes in Drosophila. Science. 243:1989;943-947.
17. Chalfie M., Tu Y., Euskirchen G., Ward W.W., Prasher D.C. Green fluorescent protein as a marker for gene expression. Science. 263:1994;802-805.
18. Chandy K.G., Gutman G.A. Nomenclature for mammalian potassium channel genes. Trends Pharmac. Sci. 14:1993;434.
19. + channel genes. In CRC Handbook of Receptors and Channels (North P.A., Ed.), pp. 1-71. CRC Press Boca Raton, FL.
20. Chen T.-Y., Peng Y.W., Dhallan R.S., Ahamed B., Reed R.R., Yau K.W. A new subunit of the cyclic nucleotide-gated cation channel in retinal rods. Nature. 362:1993;764-767.
21. Christie M.J., North R.A., Osborne P.B., Douglass J., Adelman J.P. Heteropolymeric potassium channels expressed in Xenopus oocytes from cloned subunits. Neuron. 4:1990;405-411.
22. Connor J.A., Stevens C.F. Voltage-clamp studies of a transient outward membrane current in gastropod neural somata. J. Physiol. 213:1971;21-30.
23. + current systems. Neuron. 7:1991;763-773.
24. Curran M., Splawski I., Timothy K.W., Vincent G.M., Green E.D., Keating M.T. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome. Cell. 80:1995;299-307.
25. Doupnik C.A., Davidson N., Lester H.A. The inward rectifer potassium channel family. Curr. Opin. Neurobiol. 5:1995;268-277.
26. + channel mRNAs from different subfamilies. J. Neurosci. 12:1992;538-548.
27. Edgar L. Blastomere culture and analysis. Meth. Cell Biol. 48:1995;303-321.
28. Elkins T., Ganetzky B. and Wu C.F. (1986) A Drosophila mutation that eliminates a calcium-dependent potassium current. Proc. Natn. Acad. Sci. U.S.A. 83: 8415-8419.
29. + channels. Science. 266:1994;1068-1072.
30. Fire A., Harrison S.W., Dixon D. A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans. Gene. 93:1990;189-198.
31. + channel with delayed rectifier properties isolated from rat brain by expression cloning. Nature. 340:1989;642-645.
32. + channels. Proc. R. Soc. Lond. Ser. B: Biol. Sci. 261:1995;251-261.
33. Gordon S.E., Zagotta W.N. A histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors. Neuron. 14:1995;177-183.
34. Goulding E.H., Nagi J., Kramer R.H., Colicos S., Axel R., Siegelbaum S.A., Chess A. Molecular cloning and single-channel properties of the cyclic nucleotide-grated channel from catfish olfactory neurons. Neuron. 8:1992;45-58.
35. Goulding E.H., Tibbs G.R., Siegelbaum S.A. Molecular mechanism of cyclic-nucleotide-gated channel activation. Nature. 372:1994;369-374.
36. Guy H.R., Durell S.R., Warmke J., Drysdale R., Ganetzky B. Similarities in amino acid sequences of Drosophila eag and cyclic nucleotide-gated channels. Science. 254:1991;730.
37. Hardie R.C., Voss D., Pongs O., Laughlin S.B. Novel potassium channels encoded by the Shaker locus in Drosophila photoreceptors. Neuron. 6:1991;477-486.
38. + channels. Science. 251:1991;942-944.
39. + channels. Science. 258:1992;1152-1155.
40. + channel signature sequence. Biophys. J. 66:1994;1061-1067.
41. Hille B. (1992) Ionic Channels of Excitable Membranes, 2nd Edition. Sinauer Associates, Inc., Sunderland, M.A.
42. Ho K., Nichols C.G., Lederer W.J., Lytton J., Vassilev P.M., Kanazirska M.V., Hebert S.C. Cloning and expression of an inwardly rectifying ATP-regulated potassium channel. Nature. 362:1993;31-38.
43. Hoshi T., Zagotta W.N., Aldrich R.W. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science. 250:1990;533-538.
44. KATP: an inward rectifier subunit plus the sulfonylurea receptor. Science. 270:1995;1166-1170.
45. Inagaki N., Tsuura Y., Namba N., Masuda K., Gonoi T., Horie M., Seino Y., Mizuta M., Seino S. Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart. J. Biol. Chem. 270:1995;5691-5694.
46. + chanel functions. Ann. Rev. Physiol. 54:1992;537-555.
47. Jan L.Y., Jan Y.N. Potassium channels and their evolving gates. Nature. 371:1994;119-122.
48. + channels in a primitive metazoan. J. Neurosci. 15:1995;7989-7999.
49. + channels from Paramecium Tetraurelia. Recept. Channels. 3:1995;51-60.
50. + channels. J. Cell Biol. 111:1990;60a. (Abstr.).
51. + channel gene modifies the electrical properties and synaptic efficacy of identified Aplysia neurons. Proc. Natn. Acad. Sci. U.S.A. 89:1992;1133-1137.
52. Kamb A., Iverson L.E., Tanouye M.A. Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel. Cell. 50:1987;405-413.
53. Karpen J.W., Zimmerman A.L., Stryer L., Baylor D.A. Gating kinetics of the cyclic-GMP-activated channel of retinal rods: flash photolysis and voltage-jump studies. Proc. Natn. Acad. Sci. U.S.A. 85:1988;1287-1291.
54. Katz B. (1966) Nerve, Muscle and Synapse. McGraw-Hill, New York.
55. Kaupp B.U., Niidome T., Tanabe T., Terada S., Bonigk W., Stühmer W., Cook N., Kangawa K., Matsuo H., Hirose T., Numa S. Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel. Nature. 342:1989;762-766.
56. Ketchum K.A., Joiner W.J., Sellers A.J., Kaczmarek L.K., Goldstein S.A.N. A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem. Nature. 376:1995;690-695.
57. + channels. Fedn. Eur. Biochem. Socs Lett. 378:1996;19-26.
58. Kim E., Day T.A., Bennett J.L., Pax R.A. Cloning and functional expression of a Shaker-related voltage-gated potassium channel gene from Schistosoma mansoni (Trematoda: Digenea). Parasitology. 110:1995;171-180.
59. +-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal. Genomics. 18:1993;568-574.
60. + channel from smooth muscle. J. Biol. Chem. 269:1994;17,274-17,278.
61. + channels are activated by Gβγ subunits and function as heteromultimers. Proc. Natn. Acad. Sci. U.S.A. 92:1995;6542-6546.
62. Köhler M., Hirschberg B., Bond C.T., Kinzie J.M., Marrion N.V., Maylie J., Adelman J.P. Small conductance, calcium-activated potassium channels from mammalian brain. Science. 273:1996;1709-1714.
63. + channel proteins. Nature. 374:1995;135-141.
64. Kubo Y., Baldwin T.J., Jan Y.N., Jan L.Y. Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature. 362:1993;127-133.
65. Kubo Y., Kubo Y., Reuveny E., Slesinger P.A. Primary structure and functional expression of a mouse inward rectifier potassium channel. Nature. 364:1993;802-804.
66. Kunkel M.T., Peralta E.G. Identification of domains conferring G protein regulation on inward rectifier potassium channels. Cell. 83:1995;443-499.
67. + channel probed by sulfhydryl-specific reagents after cysteine-scanning mutagenesis. Biophys. J. 68:1995;900-905.
68. + channel S4. Neuron. 16:1996;387-397.
69. + channel with a novel structure. Eur. Molec. Biol. Org. J. 15:1996;1004-1011.
70. Li M., Jan Y.N., Jan L.Y. Specification of subunit assembly by the hydrophilic amino-terminal domain of the Shaker potassium channel. Science. 257:1992;1225-1230.
71. Liman E.R., Buck L.B. A second subunit of the olfactory cyclic nucleotide-gated channel confers high sensitivity to cAMP. Neuron. 13:1994;611-621.
72. Lock L.F., Gilbert D.J., Street V.A., Migeon M.B., Jenkins N.A., Copeland N.G., Tempel B.L. Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome. Genomics. 20:1994;354-362.
73. + channel result in corresponding decreases in gating charge. Neuron. 8:1992;531-540.
74. Lopatin A.N., Makhina E.N., Nichols C.G. Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification. Nature. 372:1994;366-369.
75. + channel. Nature. 371:1994;243-246.
76. Ludwig J., Margalit T., Eismann E., Lancet D., Kaupp U.B. Primary structure of cAMP-gated channel from bovine olfactory epithelium. Fedn. Eur. Biochem. Soc. Lett. 270:1990;24-29.
77. MacKinnon R. Determination of the subunit stoichiometry of a voltage-activated potassium channel. Nature. 350:1991;232-235.
78. McManus O.B., Helms L.M., Pallanck L., Ganetzky B., Swanson R., Leonard R.J. Functional role of the beta subunit of high conductance calcium-activated potassium channels. Neuron. 14:1995;645-650.
79. Mello C.C., Kramer J.M., Stinchcomb D., Ambros V. Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences. Eur. Molec. Biol. Org. J. 10:1991;3959-3970.
80. Mikami A., Imoto K., Tanabe T., Niidome T., Mori Y., Takeshima H., Narumiya S., Numa S. Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel. Nature. 340:1989;230-233.
81. Milkman R. An Escherichia coli homologue of eukaryotic potassium channel proteins. Proc. Natn. Acad. Sci. U.S.A. 91:1994;3510-3514.
82. + currents in vivo. Neuron. 14:1995;613-623.
83. + channel expressed in potato guard cells. Eur. Molec. Biol. Org. J. 14:1995;2409-2416.
84. Noda M., Shimizu S., Tanbe T., Takai T., Kayano T., Ikeda T., Takahashi H., Kanaoka Y., Minamino N., Kangawa K., Matsuo H., Raftery M.A., Hirose T., Inayama S., Hayashida H., Miyata Y., Numa S. Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence. Nature. 312:1984;121-127.
85. + channel cloned from mammalian brain. Proc. Natn. Acad. Sci. U.S.A. 88:1991;4386-4390.
86. Papazian D.M., Schwarz T.L., Tempel B.L., Jan Y.N., Jan L.Y. Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from Drosophila. Science. 237:1987;749-753.
87. + channel. Neuron. 14:1995;1293-1301.
88. Papazian D.M., Timple L.C., Jan Y.N., Jan L.Y. Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence. Nature. 349:1991;305-310.
89. Perozo E., Santacruz-Toloza L., Stefani E., Bezanilla F., Papazian D. S4 mutations alter gating currents of Shaker K channels. Biophys. J. 66:1994;345-354.
90. + currents. J. Neurosci. 11:1991;918-927.
91. Plasterk R.H.A., Groenen J.T.M. Targeted alterations of the Caenorhabditis elegans genome by transgene instructed DNA double strand break repair following Tc1 excision. Eur. Molec. Biol. Org. J. 11:1992;287-290.
92. Pongs O., Kecskemethy N., Muller R., Krah-Jentgens I., Baumann A., Kiltz H.H., Canal I., Llamazares S., Ferrus A. Shaker encodes a family of putative potassium channel proteins in the nervous system of Drosophila. Eur. Molec. Biol. Org. J. 7:1988;1087-1096.
93. Quattrocki E.H., Marshal J., Kaczmarek L.K. A Shab potassium channel contributes to action potential broadening in peptidergic neurons. Neuron. 12:1994;73-86.
94. Ramirez-Latorre J., Yu C.R., Qu X., Perin F., Karin A., Role L. Functional contributions of α5 subunit to neuronal actylcholine receptor channel. Nature. 28:1996;347-352.
95. + channels altered by presence of beta-subunit. Nature. 369:1994;289-294.
96. Rettig J., Wunder F., Stocker M., Lichtinghagen R., Mastiaux F., Beckh S., Kues W., Pedarzani P., Schroter K.H., Ruppersberg J.P., Veh R., Pongs O. Characterization of a Shaw-related potassium channel family in the brain. Eur. Molec. Biol. Org. J. 11:1992;2473-2486.
97. Ruppersberg J.P., Schroter K.H., Sakmann B., Stocker M., Sewing S., Pongs O. Heteromultimeric channels formed by rat brain potassium-channel proteins. Nature. 345:1990;535-537.
98. + channels conserved in flies, mice and humans. Trends Neurosci. 15:1992;161-166.
99. Schrempf H., Schmidt O., Kummerlen R., Hinnah S., Muller D., Betzler M., Steinkamp T., Wagner R. A prokaryotic potassium ion channel with two predicted transmembrane segments from Streptomyces lividans. Eur. Molec. Biol. Org. J. 14:1995;5170-5178.
100. + channel components from the Shaker locus and differential distribution of splicing variants in Drosophila. Neuron. 2:1990;119-127.
101. + channels from bovine brain. Proc. Natn. Acad. Sci. U.S.A. 91:1994;1637-1641.
102. Seeburg P.H. The TiPS/TINS lecture: The molecular biology of mammalian glutamate receptor channels. Trends Pharmac. Sci. 14:1993;297-303.
103. Sentenac H., Bonneaud N., Minet M., Lacrout F., Salmon J.M., Gaymard F., Grignon C. Cloning and expression in yeast of a plant potassium ion transport system. Science. 256:1992;663-665.
104. + channel assembly. Neuron. 11:1993;67-76.
105. + channel subunit proteins. Neuron. 14:1995;625-633.
106. + channels detected in vivo. Nature. 365:1993;72-75.
107. Slesinger P.A., Reuveny E., Jan Y.N., Jan L.Y. Identification of structural elements involved in G protein gating of the GIRK1 potassium channel. Neuron. 15:1995;1145-1156.
108. Smith P.L., Baukrowitz T., Yellen G. The inward rectification mechanism of the HERG cardiac potassium channel. Nature. 379:1996;833-836.
109. 2+ of the inward rectifier, IRK1. J. Physiol. 478:1994;1-6.
110. Strong M., Chandy K.G., Gutman G.A. Molecular evolution of voltage-sensitive ion channel genes: on the origins of electrical excitability. Mol. Biol. Evolut. 10:1993;221-242.
111. Swofford D.L. (1993) Phylogenetic analysis using parsimony. Illinois Natural History Survey. Champaign, IL.
112. + channel critical foractivation by G protein βγ units. Neuron. 13:1994;747-755.
113. Tanabe T., Takeshima H., Mikama A., Flockerzi V., Takahashi H., Kangawa K., Kojima M., Matsuo H., Hirose T., Numa S. Primary structure of the receptor for calcium channel blockers from skeletal muscle. Nature. 328:1987;313-318.
114. Trudeau M.C., Warmke J.W., Ganetzky B., Robertson G.A. HERG, a human inward rectifier in the voltage-gated potassium channel family. Science. 269:1995;92-95.
115. Tsunoda S., Salkoff L. Genetic analysis of Drosophila neurons: Shal, Shaw, and Shab encode most embryonic potassium currents. J. Neurosci. 15:1995;1741-1754.
116. + channels in terminal and juxtaparanodal regions of neurons. Nature. 365:1993;75-79.
117. Wang Q., Curran M.E., Splawski I., Burn T.C., Millholland J.M., VanRaay T.J., Shen J., Timothy K.W., Vincent G.M., de Jager T., Schwartz P.J., Towbin J.A., Moss A.J., Atkinson D.L., Landes G.M., Conners T.D., Keating M.T. Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias. Nature Genet. 12:1996;17-23.
118. Warmke J., Drysdale R., Ganetzky B. A distinct potassium channel polypeptide encoded by the Drosophila eag locus. Science. 252:1991;1560-1562.
119. Warmke J., Ganetzky B. A family of potassium channel genes related to eag in Drosophila and mammals. Proc. Natn. Acad. Sci. U.S.A. 91:1994;3438-3442.
120. Weber I.T., Sietz T.A. Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5Å resolution. J. Molec. Biol. 198:1987;311-326.
121. + current diversity is produced by an extended gene family conserved in Drosophila and mouse. Science. 248:1990;599-603.
122. Ca channels determined by a separable domain. Neuron. 13:1994;671-681.
123. + channels localized to a single negatively charged residue. Nature. 371:1994;246-249.
124. Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J., Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M., Dear S., Du Z., Durbin R., Favello A., Fulton L., Gardner A., Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M., Kershaw J., Kirsten J., Laister N., Latrielle P., Lightning J., Lloyd C., McMurray A., Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A., Saunders D., Showkeen R., Smaldon N., Smith A., Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K., Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L., Wilkinson-Sproat J., Wohldman P. 2.2 Mb of continguous nucleotide sequence from chromosome III of C. elegans. Nature. 368:1994;32-38.
125. Wood W.B., editor (1988) The Nematode Caenorhabditis elegans. Cold Spring Harbor Laboratory, Cold Spring Harbor, U.S.A.
126. Yang N., George A.L. Jr., Horn R. Molecular basis of charge movement in voltage-gated sodium channels. Neuron. 16:1996;113-122.
127. + channel by mutation of the H5 region. Nature. 349:1991;700-704.
128. Zagotta W.N., Hoshi T., Aldrich R.W. Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB. Science. 250:1990;568-571.
129. + channels from Aplysia capable of contributing to the resting potential and firing patterns of neurons. Neuron. 13:1994;1205-1213.
130. + channel in the plasma membrane of yeast. FEBS Lett. 373:1995;170-176.
131. Zorio D.A., Cheng N.N., Blumenthal T., Spieth J. Operons as a common form of chromosomal organization in C. elegans. Nature. 372:1994;270-272.