Blockade of HERG and Kv1.5 by ketoconazole

Journal of Pharmacology and Experimental Therapeutics

Volumn 286, Issue 2, 1998, Pages 727-735

  Dumaine, Robert ^a,b   Roy, Mary Louise ^a   Brown, Arthur M ^a  

^a METROHEALTH MEDICAL CENTER   (United States)

^b MASONIC MEDICAL RESEARCH LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIARRHYTHMIC AGENT; CYTOCHROME P450; ERYTHROMYCIN; KETOCONAZOLE; TERFENADINE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIFUNGAL ACTIVITY; ARTICLE; CARDIOVASCULAR FUNCTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEART REPOLARIZATION; HUMAN; HUMAN CELL; ION CURRENT; LONG QT SYNDROME; MEMBRANE POTENTIAL; MICROELECTRODE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR GENE; TORSADE DES POINTES;

ACTION POTENTIALS; ANIMALS; ANTIFUNGAL AGENTS; CATION TRANSPORT PROTEINS; DNA-BINDING PROTEINS; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; ETHER-A-GO-GO POTASSIUM CHANNELS; HEART; HISTAMINE H1 ANTAGONISTS; HUMANS; KETOCONAZOLE; KV1.5 POTASSIUM CHANNEL; MEMBRANE POTENTIALS; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; TERFENADINE; TRANS-ACTIVATORS; XENOPUS;

EID: 0032411213     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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