Inhibition of human ether a go-go potassium channels by Ca2+/calmodulin

EMBO Journal

Volumn 19, Issue 13, 2000, Pages 3263-3271

  Schönherr, Roland ^a   Löber, Karsten ^a   Heinemann, Stefan H ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Calcium; Calmodulin; Patch clamp; Potassium channel; Xenopus oocyte

Indexed keywords

CALCIUM ION; CALMODULIN; GLUTATHIONE TRANSFERASE; POTASSIUM CHANNEL; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CONTROLLED STUDY; ION CURRENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN BINDING; XENOPUS;

ANIMALIA;

EID: 0342646981     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.13.3263     Document Type: Article

References (35)

1. h-eag, contributes to the hyperpolatization of human fusion-competent myoblasts. J. Physiol., 512, 317-323.
2. Brüggemann, A., Stühmer, W. and Pardo, L.A. (1997) Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopus oocytes. Proc. Natl Acad. Sci. USA, 94, 537-542.
3. Ehlers, M.D., Zhang, S., Bernhardt, J.P. and Huganir, R.L. (1996) Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit. Cell, 84, 745-755.
4. Ca channel, IKCa1. J. Biol. Chem., 274, 5746-5754.
5. + current in rod inner segments. J. Gen. Physiol., 111, 583-599.
6. Grunwald, M.E., Yu, W.-P., Yu, H.-H. and Yau, K.-W. (1998) Identification of a domain on the β-subunit of the rod cGMP-gated cation channel that mediates inhibition by calcium-calmodulin. J. Biol. Chem., 273, 9148-9157.
7. Grunwald, M.E., Zhong, H. and Yau, K.-W. (1999) Molecular determinants of the modulation of cyclic nucleotide-activated channels by calmodulin. Proc. Natl Acad. Sci. USA, 96, 13444-13449.
8. Hille, B. (1992) Ionic Channels of Excitable Membranes. Sinauer Associates Inc., MA.
9. Ho, S.N., Hunt, H.D., Horton, R.M., Pullen, J.K. and Pease, L.R. (1989) Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene. 77, 51-59.
10. James, P., Vorherr, T. and Carafoli, E. (1995) Calmodulin-binding domains: just two-faced or multi-faceted? Trends Biochem. Sci., 20, 38-42.
11. + channels. Proc. Natl Acad. Sci. USA, 96, 10917-10921.
12. 2+-activated potassium channels. J. Neurosci., 19, 8830-8838.
13. 2+/calmodulin binds to and modulates P/Q-type calcium channels. Nature, 399, 155-159.
14. + channel determined by construction of multimeric cDNAs. Neuron, 9, 861-871.
15. Liu, M., Chen, T.-Y., Ahamed, B., Li, J. and Yau, K.W. (1994) Calcium-calmodulin modulation of the olfactory nucleotide-gated cation channel. Science, 266, 1348-1354.
16. Ludwig, J., Terlau, H., Wunder, F., Brüggemann, A., Pardo, L.A., Marquardt, A., Stühmer, W. and Pongs, O. (1994) Functional expression of a rat homologue of the voltage gated eiher à go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart. EMBO J., 13, 4451-4458.
17. Meyer, R. and Heinemann, S.H. (1998) Characterization of an eag-like potassium channel in human neuroblastoma cells. J. Physiol., 508, 49-56.
18. Meyer, R., Schönherr, R., Gavrilova-Ruch, O., Wohlrab, W. and Heinemann, S.H. (1999) Identification of ether à go-go and calcium-activated potassium channels in human melanoma cells. J. Membr. Biol., 171, 107-115.
19. Molday, R.S. (1996) Calmodulin regulation of cyclic-nucleotide-gated channels. Curr. Opin. Neurobiol., 6, 445-452.
20. Neher, E. (1995) The use of Fura-2 for estimating Ca buffers and Ca fluxes. Neuropharmacology, 34, 1423-1442.
21. Occhiodoro, T., Bernheim, L., Liu, J.-H., Bijlenga, P., Sinnreich, M., Bader, C.R. and Fischer-Lougheed, J. (1998) Cloning of a human ether à go-go potassium channel expressed in myoblasts at the onset of fusion. FEBS Lett., 434, 177-182.
22. + channels. J. Cell Biol., 143, 767-775.
23. + channels. EMBO J., 18, 5540-5547.
24. 2+-dependent inactivation of L-type calcium channels. Neuron, 22, 549-558.
25. 2+ channel depends on calmodulin. Proc. Natl Acad. Sci. USA, 96, 2435-2438.
26. Rhoads, A.R. and Friedberg, F. (1997) Sequence motifs for calmodulin recognition. FASEB J., 11, 331-340.
27. + channel with a unique pattern of expression in the cerebral cortex. J. Neurosci., 19, 10789-10802.
28. Santella, L. (1998) The role of calcium in the cell cycle: facts and hypotheses. Biochem. Biophys. Res. Commun., 244, 317-324.
29. Stansfeld, C.E., Röper, J., Ludwig, J., Weseloh, R.M., Marsh, S.J., Brown, D.A. and Pongs, O. (1996) Elevation of intracellular calcium by muscarinic receptor activation induces block of voltage-activated rat ether-à-go-go channels in a stably transfected cell line. Proc. Natl Acad. Sci. USA, 93, 9910-9914.
30. Stühmer, W., Terlau, H. and Heinemann, S.H. (1992) Xenopus oocytes for two electrode and patch clamp recording. In Kettenmann, H. and Grantyn, R. (eds), Practical Electrophysiological Methods. Wiley-Liss, New York, NY, pp. 121-125.
31. 2+ regulates activation of rat eag potassium channel. Pflügers Arch., 432, 301-312.
32. Tsien, R.Y. and Rink, T.J. (1980) Neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium. Biochim. Biophys. Acta, 599, 623-638.
33. Weitz, D., Zoche, M., Muller, F., Beyermann, M., Körschen, H.G., Kaupp, U.B. and Koch, K.-W. (1998) Calmodulin controls the rod photoreceptor CNG channel through an unconventional binding site in the N-terminus of the β-subunit. EMBO J., 17, 2273-2284.
34. Xia, X.-M. et al. (1998) Mechanism of calcium gating in small-conductance calcium-activated potassium channels. Nature, 395, 503-507.
35. Zühlke, R.D., Pitt, G.S., Deisseroth, K., Tsien, R.W. and Reuter, H. (1999) Calmodulin supports both inactivation and facilitation of L-type calcium channels. Nature, 399, 159-162.