-
3
-
-
0033135564
-
CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1243-1252
-
-
Abrams, J.R.1
Lebwohl, M.G.2
Guzzo, C.A.3
Jegasothy, B.V.4
Goldfarb, M.T.5
Goffe, B.S.6
Menter, A.7
Lowe, N.J.8
Krueger, G.9
Brown, M.J.10
Weiner, R.S.11
Birkhofer, M.J.12
Warner, G.L.13
Berry, K.K.14
Linsley, P.S.15
Krueger, J.G.16
Ochs, H.D.17
Kelley, S.L.18
Kang, S.19
-
4
-
-
0032519956
-
IL-10 is a key cytokine in psoriasis. Proof of principle by IL-10 therapy: A new therapeutic approach
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 783-794
-
-
Asadullah, K.1
Sterry, W.2
Stephanek, K.3
Jasulaitis, D.4
Leupold, M.5
Audring, H.6
Volk, H.D.7
Docke, W.D.8
-
9
-
-
0033557174
-
312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions
-
(1999)
J. Exp. Med.
, vol.189
, pp. 711-718
-
-
Ozawa, M.1
Ferenczi, K.2
Kikuchi, T.3
Cardinale, I.4
Austin, L.M.5
Coven, T.R.6
Burack, L.H.7
Krueger, J.G.8
-
12
-
-
0021223740
-
Monoclonal antibody analysis of keratin expression in epidermal diseases: A 48- and 56-Kdalton keratin as molecular markers for hyperproliferative keratinocytes
-
(1984)
J. Cell Biol.
, vol.98
, pp. 1397-1406
-
-
Weiss, R.A.1
Eichner, R.2
Sun, T.-T.3
-
22
-
-
0028126761
-
GM-CSF activates regenerative epidermal growth and stimulates keratinocyte proliferation in human skin in vivo
-
(1994)
J. Invest. Dermatol.
, vol.103
, pp. 601-604
-
-
Braunstein, S.1
Kaplan, G.2
Gottlieb, A.B.3
Schwartz, M.4
Walsh, G.5
Abalos, R.M.6
Fajardo, T.T.7
Guido, L.S.8
Krueger, J.G.9
-
23
-
-
0028809898
-
Successful ultraviolet B treatment of psoriasis is accompanied by a reversal of keratinocyte pathology and by selective depletion of intraepidermal T cells
-
(1995)
J. Exp. Med.
, vol.182
, pp. 2057-2068
-
-
Krueger, J.G.1
Wolfe, J.T.2
Nabeya, R.T.3
Vallat, V.P.4
Gilleaudeau, P.5
Heftler, N.S.6
Austin, L.M.7
Gottlieb, A.B.8
-
24
-
-
0029617597
-
Elevated numbers of proliferating mononuclear cells in the peripheral blood of psoriatic patients correlate with disease severity
-
(1995)
J. Invest. Dermatol.
, vol.105
, pp. 733-738
-
-
Jeffes III, E.W.1
Lee, G.C.2
Said, S.3
Sabahi, M.4
McCullough, J.L.5
Herrod, R.6
Alzona, C.P.7
Linden, K.G.8
Soundararajan, D.9
Edwards, S.10
Weinstein, G.D.11
-
27
-
-
0345251966
-
Interleukin 10 treatment of psoriasis: Clinical results of a phase 2 trial
-
(1999)
Arch. Dermatol.
, vol.135
, pp. 187-192
-
-
Asadullah, K.1
Docke, W.D.2
Ebeling, M.3
Friedrich, M.4
Belbe, G.5
Audring, H.6
Volk, H.D.7
Sterry, W.8
-
28
-
-
0033404492
-
Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 1527-1537
-
-
Trepicchio, W.T.1
Ozawa, M.2
Walters, I.B.3
Kikuchi, T.4
Gilleaudeau, P.5
Bliss, J.L.6
Schwertschlag, U.7
Dorner, A.J.8
Krueger, J.G.9
-
30
-
-
0028990380
-
Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis
-
(1995)
Nat. Med.
, vol.1
, pp. 442-447
-
-
Gottlieb, S.L.1
Gilleaudeau, P.2
Johnson, R.3
Estes, L.4
Woodworth, T.G.5
Gottlieb, A.B.6
Krueger, J.G.7
-
33
-
-
0024869259
-
A perspective of psoriasis as an aberration in skin modified to expression by the inflammatory/repair system
-
Immune Mechanisms in Cutaneous Disease; Norris, D. A., Ed.; Marcel Dekker: New York
-
(1989)
, pp. 425-445
-
-
Krueger, G.G.1
-
34
-
-
0029565083
-
Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis
-
(1995)
Cell
, vol.83
, pp. 957-968
-
-
Carroll, J.M.1
Romero, M.R.2
Watt, F.M.3
-
40
-
-
0032524357
-
New twists in gene regulation by glucocorticoid receptor: Is DNA binding dispensable?
-
(1998)
Cell
, vol.93
, pp. 487-490
-
-
Karin, M.1
-
47
-
-
0022648655
-
3, for psoriasis: Report of five cases
-
(1986)
Calcif. Tissue Int.
, vol.38
, pp. 119-122
-
-
Morimoto, S.1
Onishi, T.2
Imanaka, S.3
Yukawa, H.4
Kozuka, T.5
Kitano, Y.6
Yoshikawa, K.7
-
53
-
-
0026033709
-
Simultaneous assessment of inflammation and epidermal proliferation in psoriatic plaques during long-term treatment with the vitamin D3 analogue MC903: Modulations and interrelations
-
(1991)
Br. J. Dermatol.
, vol.124
, pp. 221-229
-
-
De Jong, E.M.1
Van de Kerkhof, P.C.2
-
58
-
-
0005374834
-
Cloning and expression of full-length cDNA encoding human vitamin D receptor
-
(1988)
Proc. Natl. Acad. Sci. U.S.A.
, vol.85
, pp. 3294-3298
-
-
Baker, A.R.1
McDonnell, D.P.2
Hughes, M.3
Crisp, T.M.4
Mangelsdorf, D.J.5
Haussler, M.R.6
Pike, J.W.7
Shine, J.8
O'Malley, B.W.9
-
66
-
-
0025330239
-
3 with high activity for inducing epidermal differentiation but decreased hypercalcemic activity
-
(1990)
J. Dermatol.
, vol.17
, pp. 135-142
-
-
Matsunaga, T.1
Yamamoto, M.2
Mimura, H.3
Ohta, T.4
Kiyoki, M.5
Ohba, T.6
Naruchi, T.7
Hosoi, J.8
Kuroki, T.9
-
67
-
-
0029857629
-
Tacalcitol ointment in the treatment of psoriasis vulgaris: A multicentre, placebo-controlled, double-blind study on efficacy and safety
-
(1996)
Br. J. Dermatol.
, vol.135
, pp. 758-765
-
-
Van de Kerkhof, P.C.M.1
Werfel, T.2
Haustein, U.F.3
Luger, T.4
Czarnetzki, B.M.5
Niemann, R.6
Planitz-Stenzel, V.7
-
71
-
-
0030698176
-
The vitamin D analogue KH1060, is rapidly degraded both in vivo and in vitro via several pathways: Principal metabolites generated retain significant biological activity
-
(1997)
Endocrinology
, vol.138
, pp. 5485-5496
-
-
Dilworth, F.J.1
Williams, G.R.2
Kissmeyer, A.M.3
Nielson, J.L.4
Binderup, E.5
Calverley, M.J.6
Makin, H.L.7
Jones, G.8
-
72
-
-
0033106494
-
1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion
-
(1999)
J. Cell. Biochem.
, vol.73
, pp. 106-113
-
-
Brown, A.J.1
Ritter, C.2
Slatopolsky, E.3
Muralidharan, K.R.4
Okamura, W.H.5
Reddy, G.S.6
-
74
-
-
0002694036
-
Nongenomic rapid effects of Vitamin D
-
Vitamin D: Molecular Biology, Physiology, and Clinical Applications; Holick, M. F., Ed.; Humana Press: Totowa, NJ
-
(1999)
, pp. 195-205
-
-
Baran, D.T.1
-
75
-
-
0029794132
-
A decade of molecular biology of retinoic acid receptors
-
(1996)
FASEB J.
, vol.10
, pp. 940-954
-
-
Chambon, P.1
-
77
-
-
0000530241
-
The Retinoid receptors
-
The Retinoids: Biology, Chemistry and Medicine; Sporn, M. B., Roberts, A. B., Goodman, D. S., Eds.; Raven Press: New York
-
(1994)
, pp. 319-349
-
-
Mangelsdorf, D.J.1
Umesono, K.2
Evans, R.M.3
-
80
-
-
0030835766
-
Receptor specificity of retinoid-induced hyperplasia. Effect of RXR-selective agonists and correlation with topical irritation
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.282
, pp. 528-534
-
-
Thacher, S.M.1
Standeven, A.S.2
Athanikar, J.3
Kopper, S.4
Castilleja, O.5
Escobar, M.6
Beard, R.L.7
Chandraratna, R.A.S.8
-
84
-
-
0029827538
-
Safety, efficacy and duration of therapeutic effect of tazarotene used in the treatment of plaque psoriasis
-
(1996)
Br. J. Dermatol.
, vol.135
, pp. 32-36
-
-
Weinstein, G.D.1
-
87
-
-
0030978804
-
Retinoid antagonism of NF-IL6: Insight into the mechanism of antiproliferative effects of retinoids in Kaposi's sarcoma
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 4159-4168
-
-
Nagpal, S.1
Cai, J.2
Zheng, T.3
Patel, S.4
Masood, R.5
Lin, G.Y.6
Friant, S.7
Johnson, A.8
Smith, D.L.9
Chandraratna, R.A.S.10
Gill, P.S.11
-
91
-
-
10544244166
-
Negative regulation of two hyperproliferative keratinocyte differentiation markers by a retinoic acid receptor-specific retinoid: Insight into the mechanism of retinoid action in psoriasis
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 1783-1791
-
-
Nagpal, S.1
Thacher, S.M.2
Patel, S.3
Friant, S.4
Malhotra, M.5
Shafer, J.6
Krasinski, G.7
Asano, A.T.8
Teng, M.9
Duvic, M.10
Chandranratna, R.A.S.11
-
92
-
-
0030847171
-
Tazarotene-induced gene 2 (TIG2), a novel retinoid-responsive gene in skin
-
(1997)
J. Invest. Dermatol.
, vol.109
, pp. 91-95
-
-
Nagpal, S.1
Patel, S.2
Jacobe, H.3
DiSepio, D.4
Ghosn, C.5
Malhotra, M.6
Teng, M.7
Duvic, M.8
Chandraratna, R.A.S.9
-
93
-
-
0032425206
-
Identification and characterization of a retinoid-induced class II tumor suppressor/growth regulatory gene
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 14811-14815
-
-
DiSepio, D.1
Ghosn, C.2
Eckert, R.3
Deucher, A.4
Robinson, N.5
Duvic, M.6
Chandraratna, R.A.S.7
Nagpal, S.8
-
95
-
-
0029075736
-
Efficacy, tolerability, and safety of calcipotriol ointment in disorders of keratinization. Results of a randomized, double-blind, vehicle-controlled, right/left comparative study
-
(1995)
Arch. Dermatol.
, vol.131
, pp. 556-560
-
-
Kragballe, K.1
Steijlen, P.M.2
Ibsen, H.H.3
Van de Kerkhof, P.C.4
Esmann, J.5
Sorensen, L.H.6
Axelsen, M.B.7
-
99
-
-
0032518281
-
Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5′-nucleotidase-mediated conversion of adenine nucleotides
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 295-300
-
-
Morabito, L.1
Montesinos, M.C.2
Schreibman, D.M.3
Balter, L.4
Thompson, L.F.5
Resta, R.6
Carlin, G.7
Huie, M.A.8
Cronstein, B.N.9
-
106
-
-
0026667502
-
The enigma of cyclosporin A treatment for psoriasis: Systemic efficacy versus topical nonresponsiveness
-
(1992)
Acta Derm. Venereol.
, vol.72
, pp. 321-326
-
-
Mrowietz, U.1
-
107
-
-
84943726653
-
Intralesional cyclosporine for psoriasis. Relationship of dose, tissue levels, and efficacy
-
(1992)
Arch. Dermatol.
, vol.128
, pp. 786-790
-
-
Burns, M.K.1
Ellis, C.N.2
Eisen, D.3
Duell, E.4
Griffiths, C.E.5
Annesley, T.M.6
Hamilton, T.A.7
Birnbaum, J.E.8
Voorhees, J.J.9
-
108
-
-
0023261356
-
FK-506, a novel immunosuppressant isolated from a streptomyces II: Immunosuppressive effect of FK-506 in vitro
-
(1987)
J. Antibiot.
, vol.40
, pp. 1256-1265
-
-
Kino, T.1
Hatanaka, H.2
Miyata, S.3
Inamura, N.4
Nishiyama, M.5
Yajima, T.6
Goto, T.7
Okuhara, M.8
Kohsaka, M.9
Aoki, H.10
Ochiai, T.11
-
112
-
-
0031657805
-
Tacrolimus ointment does not affect collagen synthesis: Results of a single-center randomized trial
-
(1998)
J. Invest. Dermatol.
, vol.111
, pp. 396-398
-
-
Reitamo, S.1
Rissanen, J.2
Remitz, A.3
Granlund, H.4
Erkko, P.5
Elg, P.6
Autio, P.7
Lauerma, A.I.8
-
113
-
-
0023691846
-
FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. II: Fermentation, isolation and physicochemical and biological characteristics
-
(1988)
J. Antibiot. (Tokyo)
, vol.41
, pp. 1592-1601
-
-
Hatanaka, H.1
Kino, T.2
Miyata, S.3
Inamura, N.4
Kuroka, A.5
Goto, T.6
Tanaka, H.7
Okuhara, M.8
-
117
-
-
7344223256
-
Discovery of ascomycin analogues with potent topical but weak systemic activity for treatment of inflammatory skin diseases
-
(1998)
Curr. Pharm. Des.
, vol.4
, pp. 367-379
-
-
Mollison, K.W.1
Fey, T.A.2
Gauvin, D.M.3
Sheets, M.P.4
Smith, M.L.5
Pong, M.6
Krause, R.7
Miller, L.8
Or, Y.S.9
Kawai, M.10
Wagner, R.11
Wiedeman, P.E.12
Clark, R.F.13
Gunawardana, I.W.14
Rhoades, T.A.15
Henry, C.L.16
Tu, N.P.17
BaMaung, N.Y.18
Kopecka, H.19
Liu, L.20
Xie, Q.21
Lane, B.C.22
Trevillyan, J.M.23
Marsh, K.24
Carter, G.W.25
Chen, Y.-W.26
Hsieh, G.C.27
Luly, J.R.28
more..
-
118
-
-
0030010432
-
Clearing of psoriasis by a novel immunosuppressive macrolide
-
(1996)
J. Invest. Dermatol.
, vol.106
, pp. 701-710
-
-
Rappersberger, K.1
Meingassner, J.G.2
Fialla, R.3
Fodinger, D.4
Sterniczky, B.5
Rauch, S.6
Putz, E.7
Stutz, A.8
Wolff, K.9
-
123
-
-
0026659954
-
Liarozole, an inhibitor of retinoic acid metabolism, exerts retinoid-mimetic effects in vivo
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.262
, pp. 773-779
-
-
Van Wauve, J.1
Van Nyen, G.2
Coene, M.-C.3
Stoppie, P.4
Cools, W.5
Gossens, J.6
Borghgraef, P.7
Janssen, P.A.J.8
-
124
-
-
0031713597
-
The effects of oral liarozole on epidermal proliferation and differentiation in severe plaque psoriasis are comparable with those of acitretin
-
(1998)
Br. J. Dermatol.
, vol.139
, pp. 380-389
-
-
Kuijpers, A.L.1
Van Pelt, J.P.2
Bergers, M.3
Boegheim, P.J.4
Den Bakker, J.E.5
Siegenthaler, G.6
Van de Kerkhof, P.C.7
Schalkwijk, J.8
-
126
-
-
19244376476
-
R115866 inhibits all-trans-retinoic acid metabolism and exerts retinoidal effects in rodents
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.293
, pp. 304-312
-
-
Stoppie, P.1
Borgers, M.2
Borghgraef, P.3
Dillen, L.4
Goossens, J.5
Sanz, G.6
Szel, H.7
Van Hove, C.8
Van Nyen, G.9
Nobels, G.10
Vanden Bossche, H.11
Venet, M.12
Willemsens, G.13
Van Wauwe, J.14
-
127
-
-
0032085463
-
Administration of DAB389IL-2 to patients with recalcitrant psoriasis: A double-blind, phase II multicenter trial
-
(1998)
J. Am. Acad. Dermatol.
, vol.38
, pp. 938-944
-
-
Bagel, J.1
Garland, W.T.2
Breneman, D.3
Holick, M.4
Littlejohn, T.W.5
Crosby, D.6
Faust, H.7
Fivenson, D.8
Nichols, J.9
-
128
-
-
0031914851
-
Treatment of recalcitrant plaque psoriasis with a humanized nondepleting antibody to CD4
-
(1998)
J. Autoimmun.
, vol.11
, pp. 53-62
-
-
Bachelez, H.1
Flageul, B.2
Dubertret, L.3
Fraitag, S.4
Grossman, R.5
Brousse, N.6
Poisson, D.7
Knowles, R.W.8
Wacholtz, M.C.9
Haverty, T.P.10
Chatenoud, L.11
Bach, J.F.12
-
129
-
-
12944283147
-
Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis
-
(2000)
J. Am. Acad. Dermatol.
, vol.42
, pp. 428-435
-
-
Gottlieb, A.1
Krueger, J.G.2
Bright, R.3
Ling, M.4
Lebwohl, M.5
Kang, S.6
Feldman, S.7
Spellman, M.8
Wittkowski, K.9
Ochs, H.D.10
Jardieu, P.11
Bauer, R.12
White, M.13
Dedrick, R.14
Garovoy, M.15
-
130
-
-
0029899127
-
Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid
-
(1996)
Cell
, vol.85
, pp. 921-930
-
-
Sintchak, M.D.1
Fleming, M.A.2
Futer, O.3
Raybuck, S.A.4
Chambers, S.P.5
Caron, P.R.6
Murcko, M.A.7
Wilson, K.P.8
-
132
-
-
0034122710
-
Treatment of chronic plaque-stage psoriasis and psoriatic arthritis with mycophenolate mofetil
-
(2000)
J. Am. Acad. Dermatol.
, vol.42
, pp. 835-837
-
-
Grundmann-Kollmann, M.1
Mooser, G.2
Schraeder, P.3
Zollner, T.4
Kaskel, P.5
Ochsendorf, F.6
Boehncke, W.H.7
Kerscher, M.8
Kaufmann, R.9
Peter, R.U.10
-
134
-
-
0033596065
-
Treatment of active rheumatoid arthritis with leflunomide compared with placebo and methotrexate
-
(1999)
Arch. Intern. Med.
, vol.159
, pp. 2542-2450
-
-
Strand, V.1
Cohen, S.2
Schiff, M.3
Weaver, A.4
Fleischmann, R.5
Cannon, G.6
Fox, R.7
Moreland, L.8
Olsen, N.9
Furst, D.10
Caldwell, J.11
Kaine, J.12
Sharp, J.13
Hurley, F.14
Loew-Friedrich, I.15
-
138
-
-
0031716250
-
Investigation on a novel and specific leukotriene B4 receptor antagonist in the treatment of stable plaque psoriasis
-
(1998)
Br. J. Dermatol.
, vol.139
, pp. 396-402
-
-
Van Pelt, J.P.1
De Jong, E.M.2
Seijger, M.M.3
Van Hooijdonk, C.A.4
De Bakker, E.S.5
Van Vlijmen, I.M.6
Parker, G.L.7
Van Erp, P.E.8
Van De Kerkhof, P.C.9
-
139
-
-
0030920811
-
The regulation of CD11b integrin levels on human blood leukocytes and leukotriene B4-stimulated skin by a specific leukotriene B4 receptor antagonist (LY293111)
-
(1997)
Biochem. Pharmacol.
, vol.53
, pp. 1005-1012
-
-
Van Pelt, J.P.1
De Jong, E.M.2
Van Erp, P.E.3
Mitchell, M.I.4
Marder, P.5
Spaethe, S.M.6
Van Hooijdonk, C.A.7
Kuijpers, A.L.8
Van de Kerkhof, P.C.9
-
144
-
-
0027368311
-
Differential expression of protein kinase C isoenzymes in normal and psoriatic adult human skin: Reduced expression of protein kinase C-beta II in psoriasis
-
(1993)
J. Invest. Dermatol.
, vol.101
, pp. 553-559
-
-
Fisher, G.J.1
Tavakkol, A.2
Leach, K.3
Burns, D.4
Basta, P.5
Loomis, C.6
Griffiths, C.E.7
Cooper, K.D.8
Reynolds, N.J.9
Elder, J.T.10
Livneh, E.11
Voorhees, J.J.12
-
147
-
-
13344293711
-
Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor
-
(1996)
Science
, vol.272
, pp. 728-731
-
-
Ishli, H.1
Jirousek, M.R.2
Koya, D.3
Takagi, C.4
Xia, P.5
Clermont, A.6
Bursell, S.E.7
Kern, T.S.8
Ballas, L.M.9
Heath, W.F.10
Stramm, L.E.11
Feener, E.P.12
King, G.L.13
-
151
-
-
0024554077
-
Overexpression of transforming growth factor alpha in psoriatic epidermis
-
(1989)
Science
, vol.243
, pp. 811-814
-
-
Elder, J.T.1
Fisher, G.J.2
Lindquist, P.B.3
Bennett, G.L.4
Pittelkow, M.R.5
Coffey R.J., Jr.6
Ellingsworth, L.7
Derynck, R.8
Voorhees, J.J.9
-
157
-
-
13344262678
-
Tyrosine kinase inhibitors. 9. Synthesis and evaluation of fused tricyclic quinazoline analogues as ATP site inhibitors of tyrosine kinase activity of the epidermal growth factor receptor
-
(1996)
J. Med. Chem.
, vol.39
, pp. 918-928
-
-
Rewcastle, R.W.1
Palmer, B.D.2
Bridges, A.J.3
Hollis Showalter, H.D.4
Sun, L.5
Nelson, J.6
McMichael, A.7
Kraker, A.J.8
Fry, D.W.9
Denny, W.A.10
-
158
-
-
0030039555
-
Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor
-
(1996)
J. Med. Chem.
, vol.39
, pp. 267-276
-
-
Bridges, A.J.1
Zhou, H.2
Cody, D.R.3
Rewcastle, G.W.4
McMichael, A.5
Showalter, H.D.6
Fry, D.W.7
Kraker, A.J.8
Denny, W.A.9
-
160
-
-
0032830412
-
The rationale and strategy used to develop a series of highly potent, irreversible, inhibitors of the epidermal growth factor receptor family of tyrosine kinases
-
(1999)
Curr. Med. Chem.
, vol.6
, pp. 825-843
-
-
Bridges, A.J.1
-
161
-
-
15144355781
-
Synthesis and pharmacology of conformationally restricted raloxifene analogues: Highly potent selective estrogen receptor modulators
-
(1998)
J. Med. Chem.
, vol.41
, pp. 1272-1283
-
-
Grese, T.A.1
Pennington, L.D.2
Sluka, J.P.3
Adrian, M.D.4
Cole, H.W.5
Fuson, T.R.6
Magee, D.E.7
Phillips, D.L.8
Rowley, E.R.9
Shetler, P.K.10
Short, L.L.11
Venugopalan, M.12
Yang, N.N.13
Sato, M.14
Glasebrook, A.L.15
Bryant, H.U.16
-
165
-
-
0029811878
-
Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22692-22696
-
-
Klein, E.S.1
Pino, M.E.2
Johnson, A.T.3
Davies, P.J.A.4
Nagpal, S.5
Thacher, S.M.6
Krasinski, G.7
Chandraratna, R.A.S.8
-
166
-
-
0032941834
-
Cell type and gene-specific activity of the retinoid inverse agonist AGN 193109: Divergent effects from agonist at retinoic acid receptor-γ in human keratinocytes
-
(1999)
Cell Growth Differ.
, vol.10
, pp. 255-262
-
-
Thacher, S.M.1
Nagpal, S.2
Klein, E.S.3
Arefieg, T.4
Krasinski, G.5
Disepio, D.6
Agarwal, C.7
Johnson, A.T.8
Eckert, R.L.9
Chandraratna, R.A.S.10
-
170
-
-
0033618510
-
Peptide antagonists of the human estrogen receptor
-
(1999)
Science
, vol.285
, pp. 744-746
-
-
Norris, J.D.1
Paige, L.A.2
Christensen, D.J.3
Chang, C.Y.4
Huacani, M.R.5
Fan, D.6
Hamilton, P.T.7
Fowlkes, D.M.8
McDonnell, D.P.9
-
171
-
-
0031474156
-
Synthetic glucocorticoids that dissociate transactivation and AP-1 transrepression exhibit antiinflammatory activity in vivo
-
(1997)
Mol. Endocrinol.
, vol.11
, pp. 1245-1255
-
-
Vayssiere, B.M.1
Dupont, S.2
Choquart, A.3
Petit, F.4
Garcia, T.5
Marchandeau, C.6
Gronemeyer, H.7
Resche-Rigon, M.8
-
174
-
-
0028804937
-
Role of retinoic acid receptor gamma in the Rhino mouse and rabbit irritation models of retinoic acitivity
-
(1995)
Skin Pharmacol.
, vol.8
, pp. 292-299
-
-
Reczek, P.R.1
Ostrowski, J.2
Yu, K.L.3
Chen, S.4
Hammer, L.5
Roalsvig, T.6
Starrett, J.E.7
Driscoll, J.P.8
Whiting, G.9
Spinazze, P.G.10
-
176
-
-
15844376848
-
Retinoic acid receptor beta, gamma-selective ligands: Synthesis and biological activity of 6-substituted 2-naphthoic acid retinoids
-
(1996)
J. Med. Chem.
, vol.39
, pp. 2411-2421
-
-
Yu, K.L.1
Spinazze, P.2
Ostrowski, J.3
Currier, S.J.4
Pack, E.J.5
Hammer, L.6
Roalsvig, T.7
Honeyman, J.A.8
Tortolani, D.R.9
Reczek, P.R.10
Mansuri, M.M.11
Starrett J.E., Jr.12
-
181
-
-
0032746173
-
A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 383-389
-
-
Su, C.G.1
Wen, X.2
Bailey, S.T.3
Jiang, W.4
Rangwala, S.M.5
Keilbaugh, S.A.6
Flanigan, A.7
Murthy, S.8
Lazar, M.A.9
Wu, G.D.10
-
184
-
-
0034030527
-
Troglitazone improves psoriasis and normalizes models of proliferative skin disease: Ligands for peroxisome proliferater-activated receptor-gamma inhibit keratinocyte proliferation
-
(2000)
Arch. Dermatol.
, vol.136
, pp. 609-616
-
-
Ellis, C.N.1
Varani, J.2
Fisher, G.J.3
Zeigler, M.E.4
Pershadsingh, H.A.5
Benson, S.C.6
Chi, Y.7
Kurtz, T.W.8
-
185
-
-
0034733039
-
Requirement for RORγ in thymocyte survival and lymphoid organ development
-
(2000)
Science
, vol.288
, pp. 2369-2373
-
-
Sun, Z.1
Unutmaz, D.2
Zou, Y.-R.3
Sunshine, M.J.4
Pierani, A.5
Brenner-Morton, S.6
Mebius, R.E.7
Littman, D.R.8
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