Localization of endothelial proliferation and microvascular expansion in active plaque psoriasis

British Journal of Dermatology

Volumn 136, Issue 6, 1997, Pages 859-865

  Creamer, D ^a   Allen, M H ^a   Sousa, A ^b   Poston, R ^b   Barker, J N W N ^a,c  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

^c ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ANGIOGENESIS; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; DERMIS; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PSORIASIS; SKIN BLOOD FLOW;

EID: 0030741782     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2133.1997.tb03925.x     Document Type: Article

References (33)

1. Mordovtsev VN, Albanova VI. Morphology of skin microvasculature in psoriasis. Am J Dermatopathol 1989; 11: 33-42.
2. Bull RH, Bates DO, Mortimer PS. Intravital video-capillaroscopy for the study of the microcirculation in psoriasis. Br J Dermatol 1992; 126: 436-45.
3. Barton SP, Abdullah MS, Marks R. Quantification of microvascular changes in the skin in patients with psoriasis. Br J Dermatol 1992; 126: 569-74.
4. Speight EL, Essex TJH, Farr PM. The study of plaques of psoriasis using a scanning laser-Doppler velocimeter. Br J Dermatol 1993; 128: 519-24.
5. Telner P, Fekete Z. The capillary responses in psoriatic skin. J Invest Dermatol 1961; 36: 225-30.
6. Folkman J. Angiogenesis in psoriasis: therapeutic implications. J Invest Dermatol 1972; 59: 40-3.
7. Diaz-Flores L, Gutierrez R, Varela H. Angiogenesis: an update. Histol Histopathol 1994; 9: 807-43.
8. Folkman J, Hauden schild C. Angiogenesis in vitro. Nature 1980; 288: 551-6.
9. Luscinskas FW, Lawler J. Integrins as dynamic regulators of vascular function. FASEB J 1994; 8: 929-38.
10. Ingber DE. Extracellular matrix as a solid-state regulator in angiogenesis: identification of new targets for anti-cancer therapy. Semin Cancer Biol 1992; 3: 57-63.
11. Malhotra R, Stenn KS, Fernandez LA, Braverman I. Angiogenic properties of normal and psoriatic skin associate with epidermis, not dermis. Lab Invest 1989; 61: 162-5.
12. Elder JT, Fisher GJ, Lindquist PB et al. Overexpression of transforming growth factor alpha in psoriatic epidermis. Science 1989; 243: 811-14.
13. Nickoloff BJ, Mitra RS, Varani J et al. Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis. Am J Pathol 1994; 144: 820-8.
14. Detmar M, Brown LF, Claffey KP et al. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis. J Exp Med 1994; 180: 1141-6.
15. Ettehadi P, Greaves MW, Wallach D et al. Elevated tumour necrosis factor-alpha (TNF-a) biological activity in psoriatic skin lesions. Clin Exp Immunol 1994; 96: 146-51.
16. Creamer D, Jaggar R, Allen M et al. Vascular proliferation and expression of the angiogenic factor, platelet-derived endothelial cell growth factor/thymidine phosphorylase (PDECGF/TP) in psoriasis. J Invest Dermatol 1996; 106: 835 (abstract).
17. Brooks PC, Clark RAF, Cheresh DA. Requirement of vascular integrin αvβ3 for angiogenesis. Science 1994; 264: 569-71.
18. Creamer D, Allen M, Sousa A et al. Altered vascular endothelium integrin expression in psoriasis. Am J Pathol 1995; 147: 1661-7.
19. Braverman IM. Microcirculation. In: Psoriasis (Roenigk Jr HH, Maibach H, eds), 2nd edn. New York: Marcel Dekker, 1991: 447-59.
20. Bacharach-Buhles M, Panz B, El-Gammal S et al. The elongation of psoriatic capillaries, the result of epidermal hyperplasia, not of angiogenesis. J Invest Dermatol 1994; 103: 263 (abstract).
21. Morganroth GS, Chan LS, Weinstein GD et al. Proliferating cells in psoriatic dermis are comprised primarily of T cells, endothelial cells and factor XIIIa + perivascular dendritic cells. J Invest Dermatol 1991; 96: 333-40.
22. Allen MH, Markey AC, Mac-Donald DM. The development of a reproducible immunocytochemical technique for co-localising cutaneous antigens. Am J Dermatopathol 1991; 13: 221-7.
23. Schmidt D, von Hochstetter AR. The use of CD31 and collagen IV as vascular markers. A study of 56 vascular lesions. Pathol Res Prac 1995; 191: 410-14.
24. Braverman IM, Yen A. Ultrastructure of the capillary loops in the dermal papillae of psoriasis. J Invest Dermatol 1977; 68: 53-60.
25. Poston RN, Gall NP. Hue-saturation-intensity colour image analysis for the quantification of immunoperoxidase staining. In: Transactions of the Royal Microscopical Society: Micro 90. (Elder HY. ed.), Vol. 1. New York: Adam Hilger, 1990: 525-8.
26. van Erp PE, De Mare S, Rijzewijk JJ et al. A sequential double enzymic staining procedure to obtain cell kinetic information in normal and hyperproliferative epidermis. Histochem J 1989; 21: 343-7.
27. Braverman IM, Sibley BA. Role of the microcirculation in the treatment and pathogenesis of psoriasis. J Invest Dermatol 1982; 78: 12-17.
28. Silvestrini R, Costa A, Vereroni S et al. Comparative analysis of different approaches to investigate cell kinetics. Cell Tissue Res 1988; 21: 123-31.
29. Garcia RL, Coltrera MD, Gown AM. Analysis of proliferative grade using anti-PCNA/cyclin monoclonal antibodies in fixed, embedded tissues. Am J Pathol 1989; 134: 733-9.
30. Sawhney N, Hall PA. Ki67 - Structure, function and new antibodies. J Pathol 1992; 168: 161-2.
31. Wrone-Smith T, Nickoloff B. Dermal injection of immunocytes induces psoriasis. J Clin Invest 1996; 98: 1878-87.
32. Fox SB, Gatter KC, Bicknell R et al. Relationship of endothelial cell proliferation to tumor vascularity in human breast cancer. Cancer Res 1993; 53: 4161-3.
33. Pinkus H, Mehregan AH. The primary histologic lesion of seborrheic dermatitis and psoriasis. J Invest Dermatol 1966; 46: 109-16.