메뉴 건너뛰기




Volumn 103, Issue 9, 1999, Pages 1243-1252

CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

(19)  Abrams, Judith R a   Lebwohl, Mark G b   Guzzo, Cynthia A c   Jegasothy, Brian V d   Goldfarb, Michael T e   Goffe, Bernard S f   Menter, Alan g   Lowe, Nicholas J h   Krueger, Gerald i   Brown, Michael J a   Weiner, Russell S a   Birkhofer, Martin J a   Warner, Garvin L j   Berry, Karen K a   Linsley, Peter S k   Krueger, James G l   Ochs, Hans D m   Kelley, Susan L a   Kang, Sewon e  


Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; CYTOTOXIC LYMPHOCYTE; HUMAN; HUMAN TISSUE; LYMPHOCYTE ACTIVATION; PATHOGENESIS; PRIORITY JOURNAL; PSORIASIS VULGARIS; SIGNAL TRANSDUCTION;

EID: 0033135564     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI5857     Document Type: Article
Times cited : (582)

References (50)
  • 2
    • 0025820651 scopus 로고
    • T-lymphocyte-activating properties of epidermal antigen-presenting cells from normal and psoriatic skin: Evidence that psoriatic epidermal antigen-presenting cells resemble cultured normal Langerhans cells
    • Demidem, A., Taylor, R., Grammer, S.F., and Streilein, J.W. 1991. T-lymphocyte-activating properties of epidermal antigen-presenting cells from normal and psoriatic skin: evidence that psoriatic epidermal antigen-presenting cells resemble cultured normal Langerhans cells. J. Invest. Dermatol. 97:454-460.
    • (1991) J. Invest. Dermatol. , vol.97 , pp. 454-460
    • Demidem, A.1    Taylor, R.2    Grammer, S.F.3    Streilein, J.W.4
  • 3
    • 0026485262 scopus 로고
    • T-cell activation is potentiated by cytokines released by lesional psoriatic, but not normal epidermis
    • Chang, E.Y., et al. 1992. T-cell activation is potentiated by cytokines released by lesional psoriatic, but not normal epidermis. Arch. Dermatol. 128:1479-1485.
    • (1992) Arch. Dermatol. , vol.128 , pp. 1479-1485
    • Chang, E.Y.1
  • 4
    • 0027377919 scopus 로고
    • T-lymphocyte clones initiated from lesional psoriatic skin release growth factors that induce keratinocyte proliferation
    • Strange, P., et al. 1993. T-lymphocyte clones initiated from lesional psoriatic skin release growth factors that induce keratinocyte proliferation. J. Invest. Dermatol. 101:695-700.
    • (1993) J. Invest. Dermatol. , vol.101 , pp. 695-700
    • Strange, P.1
  • 5
    • 0028842377 scopus 로고
    • Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture
    • Bata-Csorgo, Z., Hammerberg, C., Voorhees, J.J., and Cooper, K.D. 1995. Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture. J. Clin. Invest. 95:317-327.
    • (1995) J. Clin. Invest. , vol.95 , pp. 317-327
    • Bata-Csorgo, Z.1    Hammerberg, C.2    Voorhees, J.J.3    Cooper, K.D.4
  • 6
    • 0031914851 scopus 로고    scopus 로고
    • Treatment of recalcitrant plaque psoriasis with a humanized non-depleting antibody to CD4
    • Bachelez, H., et al. 1998. Treatment of recalcitrant plaque psoriasis with a humanized non-depleting antibody to CD4. J. Autoimmun. 11:53-62.
    • (1998) J. Autoimmun. , vol.11 , pp. 53-62
    • Bachelez, H.1
  • 7
    • 0028990380 scopus 로고
    • 389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis
    • 389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis. Nat. Med. 1:442-447.
    • (1995) Nat. Med. , vol.1 , pp. 442-447
    • Gottlieb, S.L.1
  • 8
    • 0018321051 scopus 로고
    • Cyclosporin A for psoriasis
    • Mueller, W., and Herrman, B. 1979. Cyclosporin A for psoriasis. N. Engl. J. Med. 301:555.
    • (1979) N. Engl. J. Med. , vol.301 , pp. 555
    • Mueller, W.1    Herrman, B.2
  • 9
    • 0024327899 scopus 로고
    • Clonal expansion versus functional inactivation: A costimulatory signaling pathway determines the outcome of T cell antigen receptor occupancy
    • Mueller, D.L., Jenkins, M.K., and Schwartz, R.H. 1989. Clonal expansion versus functional inactivation: a costimulatory signaling pathway determines the outcome of T cell antigen receptor occupancy. Annu. Rev. Immunol. 7:445-480.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 445-480
    • Mueller, D.L.1    Jenkins, M.K.2    Schwartz, R.H.3
  • 10
    • 0025963594 scopus 로고
    • Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation
    • Linsley, P.S., et al. 1991. Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation. J. Exp. Med. 173:721-730.
    • (1991) J. Exp. Med. , vol.173 , pp. 721-730
    • Linsley, P.S.1
  • 11
    • 0025830902 scopus 로고
    • CTLA-4 is a second receptor for the B cell activation antigen B7
    • Linsley, P.S., et al. 1991. CTLA-4 is a second receptor for the B cell activation antigen B7. J. Exp. Med. 174:561-569.
    • (1991) J. Exp. Med. , vol.174 , pp. 561-569
    • Linsley, P.S.1
  • 12
    • 0032543306 scopus 로고    scopus 로고
    • The role of T-cell costimulatory activation pathways in transplant rejection
    • Sayegh, M.H., and Turka, L.A. 1998. The role of T-cell costimulatory activation pathways in transplant rejection. N. Engl. J. Med. 338:1813-1821.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1813-1821
    • Sayegh, M.H.1    Turka, L.A.2
  • 13
    • 0026738641 scopus 로고
    • Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4Ig
    • Lenschow, D.J., et al. 1992. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4Ig. Science. 257:789-792.
    • (1992) Science , vol.257 , pp. 789-792
    • Lenschow, D.J.1
  • 14
    • 0027451441 scopus 로고
    • Long-term acceptance of major histocompatability complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion
    • Lin, H., et al. 1993. Long-term acceptance of major histocompatability complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion. J. Exp. Med. 178:1801-1806.
    • (1993) J. Exp. Med. , vol.178 , pp. 1801-1806
    • Lin, H.1
  • 15
    • 0028903939 scopus 로고
    • CD28-b7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2
    • Sayegh, M.H., et al. 1995. CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2. J. Exp. Med. 181:1869-1874.
    • (1995) J. Exp. Med. , vol.181 , pp. 1869-1874
    • Sayegh, M.H.1
  • 16
    • 12644262358 scopus 로고    scopus 로고
    • CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
    • Kirk, A.D., et al. 1997. CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates. Proc. Natl. Acad. Sci. USA. 94:8789-8794.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8789-8794
    • Kirk, A.D.1
  • 17
    • 0029851224 scopus 로고    scopus 로고
    • Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases
    • Reiser, H., and Stadecker, M.D. 1996. Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases. N. Engl. J. Med. 335:1369-1377.
    • (1996) N. Engl. J. Med. , vol.335 , pp. 1369-1377
    • Reiser, H.1    Stadecker, M.D.2
  • 18
    • 0028483990 scopus 로고
    • Treatment of murine lupus with CTLA4Ig
    • Finck, B.K., Linsley, P.S., and Wofsy, D. 1994. Treatment of murine lupus with CTLA4Ig. Science. 265:1225-1227.
    • (1994) Science , vol.265 , pp. 1225-1227
    • Finck, B.K.1    Linsley, P.S.2    Wofsy, D.3
  • 19
    • 0028999041 scopus 로고
    • Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation
    • Cross, A.H., et al. 1995. Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation. J. Clin. Invest. 95:2783-2789.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2783-2789
    • Cross, A.H.1
  • 20
    • 0029849012 scopus 로고    scopus 로고
    • Prevention and amelioration of collagen-induced arthritis by blockade of the CD28 costimulatory pathway: Requirement for both B7-1 and B7-2
    • Webb, L.M.C., Walmsley, M.J., and Feldmann, M. 1996. Prevention and amelioration of collagen-induced arthritis by blockade of the CD28 costimulatory pathway: requirement for both B7-1 and B7-2. Eur. J. Immunol. 26:2320-2328.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2320-2328
    • Webb, L.M.C.1    Walmsley, M.J.2    Feldmann, M.3
  • 21
    • 0028179886 scopus 로고
    • Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells
    • Larsen, C.P., et al. 1994. Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells. J. Immunol. 152:5208-5219.
    • (1994) J. Immunol. , vol.152 , pp. 5208-5219
    • Larsen, C.P.1
  • 22
    • 0027245516 scopus 로고
    • Expression and function of B7 on human epidermal Langerhans cells
    • Symington, F.W., Brady, W., and Linsley, P.S. 1993. Expression and function of B7 on human epidermal Langerhans cells. J. Immunol. 150:1286-1295.
    • (1993) J. Immunol. , vol.150 , pp. 1286-1295
    • Symington, F.W.1    Brady, W.2    Linsley, P.S.3
  • 23
    • 0028245467 scopus 로고
    • Characterization of detmal dendritic cells in psoriasis
    • Nestle, F.O., Turka, L.A., and Nickoloff, B.J. 1994. Characterization of detmal dendritic cells in psoriasis. J. Clin. Invest. 94:202-209.
    • (1994) J. Clin. Invest. , vol.94 , pp. 202-209
    • Nestle, F.O.1    Turka, L.A.2    Nickoloff, B.J.3
  • 25
    • 0029661755 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of CTLA4Ig (BMS-188667), a novel immunosuppressive agent, in monkeys following multiple doses
    • Srinivas, N.R., et al. 1996. Pharmacokinetics and pharmacodynamics of CTLA4Ig (BMS-188667), a novel immunosuppressive agent, in monkeys following multiple doses. J. Pharm. Sci. 85:1-4.
    • (1996) J. Pharm. Sci. , vol.85 , pp. 1-4
    • Srinivas, N.R.1
  • 26
    • 0015182749 scopus 로고
    • Immunologic responses to bacteriophage φX174 in immunodeficiency diseases
    • Ochs, H.D., Davis, S.D., and Wedgwood, R.J. 1971. Immunologic responses to bacteriophage φX174 in immunodeficiency diseases. J. Clin. Invest. 50:2559-2568.
    • (1971) J. Clin. Invest. , vol.50 , pp. 2559-2568
    • Ochs, H.D.1    Davis, S.D.2    Wedgwood, R.J.3
  • 27
    • 0026778697 scopus 로고
    • Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule
    • Linsley, P.S., et al. 1992. Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule. Science. 257:792-795.
    • (1992) Science , vol.257 , pp. 792-795
    • Linsley, P.S.1
  • 28
    • 0028223483 scopus 로고
    • PUVA bath therapy strongly suppresses immunological and epidermal activation in psoriasis: A possible cellular basis for remittive therapy
    • Vallat, V.P., et al. 1994. PUVA bath therapy strongly suppresses immunological and epidermal activation in psoriasis: a possible cellular basis for remittive therapy. J. Exp. Med. 180:283-296.
    • (1994) J. Exp. Med. , vol.180 , pp. 283-296
    • Vallat, V.P.1
  • 29
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli, Y., Sherman, Y., and Ben-Sasson, S.A. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell. Biol. 119:493-501.
    • (1992) J. Cell. Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 30
    • 84950451743 scopus 로고
    • Exact inference for contingency tables with ordered categories
    • Agresti, A., Mehta, C.R., and Patel, N.R. 1990. Exact inference for contingency tables with ordered categories. J. Am. Star. Assoc. 85:453-458.
    • (1990) J. Am. Star. Assoc. , vol.85 , pp. 453-458
    • Agresti, A.1    Mehta, C.R.2    Patel, N.R.3
  • 31
    • 0028949575 scopus 로고
    • Regulation of cell surface β1 integrin levels during keratinocyte terminal differentiation
    • Hotchin, N.A., Gandarillas, A., and Watt, F.M. 1995. Regulation of cell surface β1 integrin levels during keratinocyte terminal differentiation. J. Cell Biol. 128:1209-1219.
    • (1995) J. Cell Biol. , vol.128 , pp. 1209-1219
    • Hotchin, N.A.1    Gandarillas, A.2    Watt, F.M.3
  • 32
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • Gerdes, J., et al. 1984. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J. Immunol. 133:1710-1715.
    • (1984) J. Immunol. , vol.133 , pp. 1710-1715
    • Gerdes, J.1
  • 33
    • 0033557174 scopus 로고    scopus 로고
    • 312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions
    • Ozawa, M., et al. 1999. 312-nanometer ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions. J. Exp. Med. 189:711-718.
    • (1999) J. Exp. Med. , vol.189 , pp. 711-718
    • Ozawa, M.1
  • 34
    • 0029834883 scopus 로고    scopus 로고
    • Suppression of T-cell-dependent immune responses in monkeys by CTLA4Ig
    • Cabrian, K.M., et al. 1996. Suppression of T-cell-dependent immune responses in monkeys by CTLA4Ig. Transplant. Proc. 28:3261-3262.
    • (1996) Transplant. Proc. , vol.28 , pp. 3261-3262
    • Cabrian, K.M.1
  • 37
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and FAS in T cell apoptosis and peripheral tolerance
    • Van Parijs, L., Ibraghimov, A., and Abbas, A.K. 1996. The roles of costimulation and FAS in T cell apoptosis and peripheral tolerance. Immunity. 4:321-328.
    • (1996) Immunity , vol.4 , pp. 321-328
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 38
    • 0031012138 scopus 로고    scopus 로고
    • P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues
    • Austrup, F., et al. 1997. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature. 385:81-83.
    • (1997) Nature , vol.385 , pp. 81-83
    • Austrup, F.1
  • 39
    • 0025287731 scopus 로고
    • Adherence of human helper/memory T-cell subsets to psoriatic dermal endothelium
    • Chin, Y.-H., Falanga, V., Taylor, J.R., Cai, J.-P., and Bax, J. 1990. Adherence of human helper/memory T-cell subsets to psoriatic dermal endothelium. J. Invest. Dermatol. 94:413-417.
    • (1990) J. Invest. Dermatol. , vol.94 , pp. 413-417
    • Chin, Y.-H.1    Falanga, V.2    Taylor, J.R.3    Cai, J.-P.4    Bax, J.5
  • 40
    • 0027511484 scopus 로고
    • T cell receptor Vβ expression in normal human skin
    • Dunn, D., et al. 1993. T cell receptor Vβ expression in normal human skin. Proc. Natl. Acad. Sci. USA. 90:1267-1271.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1267-1271
    • Dunn, D.1
  • 41
    • 0028146528 scopus 로고
    • + T cells in psoriatic lesions preferentially use T-cell receptor Vβ3 and/or Vβ13.1 genes
    • + T cells in psoriatic lesions preferentially use T-cell receptor Vβ3 and/or Vβ13.1 genes. Proc. Natl. Acad. Sci. USA. 91:9282-9286.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9282-9286
    • Chang, J.C.C.1
  • 42
    • 0026528262 scopus 로고
    • Studies of the effect of cyclosporine in psoriasis in vivo: Combined effects on activated T lymphocytes and epidermal regenerative maturation
    • Gottlieb, A.B., et al. 1992. Studies of the effect of cyclosporine in psoriasis in vivo: combined effects on activated T lymphocytes and epidermal regenerative maturation. J. Invest. Dermatol. 98:302-309.
    • (1992) J. Invest. Dermatol. , vol.98 , pp. 302-309
    • Gottlieb, A.B.1
  • 43
    • 0030057218 scopus 로고    scopus 로고
    • T cell activation determined by T cell receptor number and tunable thresholds
    • Viola, A., and Lanzavecchia, A. 1996. T cell activation determined by T cell receptor number and tunable thresholds. Science. 273:104-106.
    • (1996) Science , vol.273 , pp. 104-106
    • Viola, A.1    Lanzavecchia, A.2
  • 44
    • 0031884839 scopus 로고    scopus 로고
    • The duration of antigenic stimulation determines the fate of naive and effector T cells
    • Iezzi, G., Karjalainen, K., and Lanzavecchia, A. 1998. The duration of antigenic stimulation determines the fate of naive and effector T cells. Immunity. 8:89-95.
    • (1998) Immunity , vol.8 , pp. 89-95
    • Iezzi, G.1    Karjalainen, K.2    Lanzavecchia, A.3
  • 45
    • 0029914089 scopus 로고    scopus 로고
    • Covalent dimerization of CD28/CTLA-4 and oligomerization of CD80/CD86 regulate T cell costimulatory interactions
    • Greene, J.L., et al. 1996. Covalent dimerization of CD28/CTLA-4 and oligomerization of CD80/CD86 regulate T cell costimulatory interactions. J. Biol. Chem. 271:26762-26771.
    • (1996) J. Biol. Chem. , vol.271 , pp. 26762-26771
    • Greene, J.L.1
  • 46
    • 0029899783 scopus 로고    scopus 로고
    • CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
    • Krummel, M.F., and Allison, J.P. 1996. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells. J. Exp. Med. 183:2533-2540.
    • (1996) J. Exp. Med. , vol.183 , pp. 2533-2540
    • Krummel, M.F.1    Allison, J.P.2
  • 47
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
    • Tivol, E.A., et al. 1995. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity. 3:541-547.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1
  • 48
    • 0031154577 scopus 로고    scopus 로고
    • CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice
    • Tivol, E.A., et al. 1997. CTLA4Ig prevents lymphoproliferation and fatal multiorgan tissue destruction in CTLA-4-deficient mice. J. Immunol. 158:5091-5094.
    • (1997) J. Immunol. , vol.158 , pp. 5091-5094
    • Tivol, E.A.1
  • 49
    • 0033579816 scopus 로고    scopus 로고
    • B7-1 or B7-2 is required to produce the lymphoproliferarive phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)
    • Mandelbrot, D.A., McAdam, A.J., and Sharpe, A.H. 1999. B7-1 or B7-2 is required to produce the lymphoproliferarive phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4). J. Exp. Med. 189:435-440.
    • (1999) J. Exp. Med. , vol.189 , pp. 435-440
    • Mandelbrot, D.A.1    McAdam, A.J.2    Sharpe, A.H.3
  • 50
    • 0030966217 scopus 로고    scopus 로고
    • Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement
    • Perez, V.L., et al. 1997. Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. Immunity. 6:411-417.
    • (1997) Immunity , vol.6 , pp. 411-417
    • Perez, V.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.