메뉴 건너뛰기




Volumn 4, Issue 3, 2001, Pages 169-177

Anthracycline drug targeting: Cytoplasmic versus nuclear - A fork in the road

Author keywords

[No Author keywords available]

Indexed keywords

3' (3 CYANOMORPHOLINO) 3' DEAMINODOXORUBICIN; 3' DEAMINO 3' HYDROXYDOXORUBICIN; 3' DEAMINO 3' MORPHOLINODOXORUBICIN; 3' DEAMINO 3' MORPHOLINYL 13 DEOXO 10 HYDROXYCARMINOMYCIN; ACLARUBICIN; AD 445; ANTHRACYCLINE ANTIBIOTIC AGENT; CALPHOSTIN; DAUNORUBICIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; DOXORUBICIN DERIVATIVE; EPIRUBICIN; GALARUBICIN; IDARUBICIN; MEN 10746; METHOXYMORPHOLINODOXORUBICIN; MIDOSTAURIN; MORPHOLINE DERIVATIVE; N BENZYLDOXORUBICIN; N BENZYLDOXORUBICIN 14 VALERATE; N TRIFLUOROACETYLDOXORUBICIN; PIRARUBICIN; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; SABARUBICIN; STAUROSPORINE; UNCLASSIFIED DRUG; VALRUBICIN; WP 159; WP 631;

EID: 0035190606     PISSN: 13687646     EISSN: None     Source Type: Journal    
DOI: 10.1054/drup.2001.0201     Document Type: Review
Times cited : (69)

References (97)
  • 1
    • 0026714331 scopus 로고
    • The anthracyclines: Will we ever find a better doxorubicin?
    • (1992) Semin Oncol , vol.19 , pp. 670-686
    • Weiss, R.B.1
  • 6
    • 17744365161 scopus 로고    scopus 로고
    • Anthracycline metabolism and toxicity in human myocardium: Comparisons between doxorubicin, epirubicin, and a novel disaccharide analogue with a reduced level of formation and [4Fe-4S] reactivity of its secondary alcohol metabolite
    • (2000) Chem Res Toxicol , vol.13 , pp. 1336-1341
    • Minotti, G.1    Licata, S.2    Saponiero, A.3
  • 8
    • 0031714464 scopus 로고    scopus 로고
    • The role of iron in doxorubicin-induced cardiomyopathy
    • (1998) Semin Oncol , vol.25 , Issue.SUPPL. 110 , pp. 10-14
    • Myers, C.1
  • 11
    • 0032959345 scopus 로고    scopus 로고
    • Reactive oxygen intermediates as mediators of programmed cell death in plants and animals
    • (1999) Biochem Pharmacol , vol.57 , pp. 231-245
    • Jabs, T.1
  • 18
    • 0034728270 scopus 로고    scopus 로고
    • Reactive oxygen species-specific mechanisms of drug resistance in paraquat-resistant acute myelogenous leukemia sublines
    • (2000) Mol Cells , vol.10 , pp. 38-46
    • Choi, C.H.1    Kim, H.S.2    Kweon, O.S.3
  • 19
    • 0033834523 scopus 로고    scopus 로고
    • Suppression of manganese superoxide dismutase augments sensitivity to radiation, hyperthermia and doxorubicin in colon cancer cell lines by inducing apoptosis
    • (2000) Br J Cancer , vol.83 , pp. 928-934
    • Kuninaka, S.1    Ichinose, Y.2    Koja, K.3    Toh, Y.4
  • 21
    • 0030999750 scopus 로고    scopus 로고
    • Apoptosis and the dilemma of cancer chemotherapy
    • (1997) Blood , vol.89 , pp. 1845-1853
    • Hannun, Y.A.1
  • 29
    • 0023630851 scopus 로고
    • The major metabolite of doxorubicin is a potent inhibitor of membrane-associated ion pumps: A correlative study of cardiac muscle with isolated membrane fractions
    • (1987) J Biol Chem , vol.262 , pp. 15851-15856
    • Boucek, R.J.1    Olson, R.D.2    Brenner, D.E.3
  • 30
    • 0031897342 scopus 로고    scopus 로고
    • The secondary alcohol metabolite of doxorubicin irreversibly inactivates aconitase/iron regulatory protein-I in cytosolic fractions from human myocardium
    • (1998) FASEB J , vol.12 , pp. 541-552
    • Minotti, G.1    Recalcati, S.2    Mordente, A.3
  • 41
    • 0033564958 scopus 로고    scopus 로고
    • Altered multidrug resistance phenotype caused by anthracycline analogues and cytosine arabinoside in myeloid leukemia
    • (1999) Blood , vol.93 , pp. 4086-4095
    • Hu, X.F.1    Slater, A.2    Kantharidis, P.3
  • 46
    • 0031752659 scopus 로고    scopus 로고
    • The expression of mdr-I-related gp-170 and its correlation with anthracycline resistance in renal cell carcinoma cell lines and multidrug-resistant sublines
    • (1998) Br J Urol , vol.82 , pp. 544-547
    • Yu, D.S.1    Chang, S.Y.2    Ma, C.R.3
  • 58
    • 0028304459 scopus 로고
    • Influence of structural modifications at the 3′ and 4′ positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance
    • (1994) Mol Pharmacol , vol.45 , pp. 908-915
    • Capranico, G.1    Supino, R.2    Binaschi, M.3
  • 61
    • 0035866772 scopus 로고    scopus 로고
    • Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer
    • (2000) Cancer Res , vol.61 , pp. 2505-2512
    • Geisler, S.1    Lonning, P.E.2    Aas, T.3
  • 77
    • 0033678680 scopus 로고    scopus 로고
    • A peptide-doxorubicin 'prodrug' activated by prostate-specific antigen selectively kills prostate tumor cells positive for prostate-specific antigen in vivo
    • (2000) Nat Med , vol.6 , pp. 1248-1252
    • DeFeo-Jones, D.1    Garsky, V.M.2    Wong, B.K.3
  • 79
    • 0031013483 scopus 로고    scopus 로고
    • Pharmacokinetics of DA-125, a new anthracycline, after intravenous administration to spontaneously hypertensive rats and DOCA-salt-induced hypertensive rats
    • (1997) Drug Metab Dispos , vol.25 , pp. 66-74
    • Yoon, E.J.1    Shim, H.J.2    Lee, J.J.3
  • 80
    • 0030887296 scopus 로고    scopus 로고
    • Annamycin circumvents resistance mediated by the multidrug resistance-associated protein (MRP) in breast MCF-7 and small-cell lung UMCC-I cancer cell lines selected for resistance to etoposide
    • (1997) Int J Cancer , vol.71 , pp. 35-41
    • Perez-Soler, R.1    Neamati, N.2    Zou, Y.3
  • 81
    • 0030782228 scopus 로고    scopus 로고
    • Antitumor activity of DA-125, a novel anthracycline, in human gastric and pulmonary adenocarcinoma cells resistant to adriamycin and cisplatin
    • (1997) Anticancer Res , vol.17 , pp. 3613-3616
    • Hong, W.S.1    Jung, H.Y.2    Yang, S.K.3
  • 93
    • 0033973840 scopus 로고    scopus 로고
    • Efficacy and safety of valrubicin for the treatment of Bacillus Calmette-Guerin refractory carcinoma in situ of the bladder
    • The Valrubicin Study Group
    • (2000) J Urol , vol.163 , pp. 761-767
    • Steinberg, G.1    Bahnson, R.2    Brosman, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.