The secondary alcohol metabolite of doxorubicin irreversibly inactivates aconitase/iron regulatory protein-1 in cytosolic fractions from human myocardium

FASEB Journal

Volumn 12, Issue 7, 1998, Pages 541-552

  Minotti, Giorgio ^a   Recalcati, Stefania ^b   Mordente, Alvaro ^a   Liberi, Giovanni ^d   Calafiore, Antonio Maria ^d   Mancuso, Cesare ^a   Preziosi, Paolo ^a   Cairo, Gaetano ^c  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c CNR   (Italy)

^d UNIVERSITY OF CHIETI   (Italy)

Author keywords

Alcohol metabolite; Cardiotoxicity; DOXol cluster disassembly; Doxorubicin; Iron responsive elements; IRP 1

Indexed keywords

ACONITATE HYDRATASE; DOXORUBICIN; DRUG METABOLITE; IRON REGULATORY FACTOR;

ADULT; AGED; ARTICLE; CARDIOTOXICITY; CYTOSOL; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG STRUCTURE; ENZYME ACTIVITY; FEMALE; HEART MUSCLE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; TISSUE DISTRIBUTION;

EID: 0031897342     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.12.7.541     Document Type: Article

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