ATP-bound Topoisomerase II as a Target for Antitumor Drugs

Journal of Biological Chemistry

Volumn 276, Issue 19, 2001, Pages 15990-15995

  Wang, Huimin ^a   Mao, Yong ^a   Zhou, Nai ^a   Hu, Tao ^b   Hsieh, Tao Shih ^b   Liu, Leroy F ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DRUG PRODUCTS; TUMORS;

POISONS;

ADENOSINETRIPHOSPHATE;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ADENYLYLIMIDODIPHOSPHATE; AMONAFIDE; AMSACRINE; BATRACYLIN; CIPROFLOXACIN; DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); DOUBLE STRANDED DNA; DOXORUBICIN; ETOPOSIDE; GALACTOSIDASE; MENADIONE; MITOXANTRONE; TENIPOSIDE; ANTINEOPLASTIC AGENT; RECOMBINANT PROTEIN;

ARTICLE; CROSS RESISTANCE; DNA CLEAVAGE; DNA STRAND BREAKAGE; DRUG TARGETING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; REPRESSOR GENE; AMINO ACID SUBSTITUTION; ANIMAL; CATTLE; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; KINETICS; METABOLISM; SITE DIRECTED MUTAGENESIS; THYMUS;

ADENOSINE TRIPHOSPHATE; AMINO ACID SUBSTITUTION; AMSACRINE; ANIMALS; ANTINEOPLASTIC AGENTS; CATTLE; DNA TOPOISOMERASES, TYPE II; DOXORUBICIN; ETOPOSIDE; KINETICS; MITOXANTRONE; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT PROTEINS; TENIPOSIDE; THYMUS GLAND;

EID: 0035844288     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011143200     Document Type: Article

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