Degradation of the morpholino ring in the crystal structure of cyanomorpholinodoxorubicin complexed with d(CGATCG)

European Journal of Biochemistry

Volumn 258, Issue 2, 1998, Pages 350-354

  Ettorre, Alessandro ^a   Cirilli, Maurizio ^b   Ughetto, Giovanni ^b  

^a Menarini Ricerche SpA   (Italy)

^b CNR   (Italy)

Author keywords

Anthracycline; Anticancer drugs design; DNA intercalation; Drug DNA complex; X ray structure

Indexed keywords

3' (3 CYANOMORPHOLINO) 3' DEAMINODOXORUBICIN; ANTINEOPLASTIC AGENT; DAUNORUBICIN; DOXORUBICIN; MORPHOLINE DERIVATIVE;

ARTICLE; BASE PAIRING; CPG ISLAND; CROSS RESISTANCE; CRYSTAL STRUCTURE; DNA ALKYLATION; DNA CROSS LINKING; DRUG DESIGN; DRUG POTENCY; INTERCALATION COMPLEX; PRIORITY JOURNAL;

EID: 0032402680     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2580350.x     Document Type: Article

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