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Volumn 56, Issue 1, 1999, Pages 77-84

Topoisomerase poisoning activity of novel disaccharide anthracyclines

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; IDARUBICIN;

EID: 0033064653     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.56.1.77     Document Type: Article
Times cited : (63)

References (42)
  • 1
    • 0000356472 scopus 로고
    • Doxorubicin
    • Academic Press, New York
    • Arcamone F (1981) Doxorubicin, in Anticancer Antibiotics pp 1-369, Academic Press, New York.
    • (1981) Anticancer Antibiotics , pp. 1-369
    • Arcamone, F.1
  • 5
    • 0029072779 scopus 로고
    • Expression, domain structure, and enzymatic properties of an active recombinant human DNA topoisomerase II beta
    • Austin CA, Marsh KL, Wasserman RA, Willmore E, Sayer PJ, Wang JC and Fisher LM (1995) Expression, domain structure, and enzymatic properties of an active recombinant human DNA topoisomerase II beta. J Biol Chem 270:15739-15746.
    • (1995) J Biol Chem , vol.270 , pp. 15739-15746
    • Austin, C.A.1    Marsh, K.L.2    Wasserman, R.A.3    Willmore, E.4    Sayer, P.J.5    Wang, J.C.6    Fisher, L.M.7
  • 6
    • 0023061489 scopus 로고
    • A novel leader peptide which allows efficient secretion of a fragment of human interleukin 1β in Saccharomyces cerevisiae
    • Baldari C, Murray JAH, Ghiara P, Cesareni G and Galeotti CL (1987) A novel leader peptide which allows efficient secretion of a fragment of human interleukin 1β in Saccharomyces cerevisiae. EMBO J 6:229-234.
    • (1987) EMBO J , vol.6 , pp. 229-234
    • Baldari, C.1    Murray, J.A.H.2    Ghiara, P.3    Cesareni, G.4    Galeotti, C.L.5
  • 7
    • 0032080808 scopus 로고    scopus 로고
    • Human DNA topoisomerase IIalpha-dependent DNA cleavage and yeast cell killing by anthracycline analogues
    • Binaschi M, Farinosi R, Austin CA, Fisher LM, Zunino F and Capranico G (1998) Human DNA topoisomerase IIalpha-dependent DNA cleavage and yeast cell killing by anthracycline analogues. Cancer Res 58:1886-1892.
    • (1998) Cancer Res , vol.58 , pp. 1886-1892
    • Binaschi, M.1    Farinosi, R.2    Austin, C.A.3    Fisher, L.M.4    Zunino, F.5    Capranico, G.6
  • 8
    • 0024305936 scopus 로고
    • Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: Restoration of sensitivity of the cells to the antitumor drug camptothecin
    • Bjornsti MA, Benedetti P, Viglianti GA and Wang JC (1989) Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: Restoration of sensitivity of the cells to the antitumor drug camptothecin. Cancer Res 49:6318-6323.
    • (1989) Cancer Res , vol.49 , pp. 6318-6323
    • Bjornsti, M.A.1    Benedetti, P.2    Viglianti, G.A.3    Wang, J.C.4
  • 9
    • 0030826233 scopus 로고    scopus 로고
    • A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons
    • Capranico G, Binaschi M, Borgnetto ME, Zunino F and Palumbo M (1997) A protein-mediated mechanism for the DNA sequence-specific action of topoisomerase II poisons. Trends Pharmacol Sci 18:303-346.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 303-346
    • Capranico, G.1    Binaschi, M.2    Borgnetto, M.E.3    Zunino, F.4    Palumbo, M.5
  • 10
    • 0028814479 scopus 로고
    • Change of the sequence specificity of daunorubicin-stimulated topoisomerase II DNA cleavage by epimerization of the amino group of the sugar moiety
    • Capranico G, Butelli E and Zunino F (1995) Change of the sequence specificity of daunorubicin-stimulated topoisomerase II DNA cleavage by epimerization of the amino group of the sugar moiety. Cancer Res 55:312-317.
    • (1995) Cancer Res , vol.55 , pp. 312-317
    • Capranico, G.1    Butelli, E.2    Zunino, F.3
  • 12
    • 0028271476 scopus 로고
    • Conformational drug determinants of the sequence specificity of drug-stimulated topoisomerase II DNA cleavage
    • Capranico G, Palumbo M, Tinelli S, Mabilia M, Pozzan A and Zunino F (1994a) Conformational drug determinants of the sequence specificity of drug-stimulated topoisomerase II DNA cleavage. J Mol Biol 235:1218-1230.
    • (1994) J Mol Biol , vol.235 , pp. 1218-1230
    • Capranico, G.1    Palumbo, M.2    Tinelli, S.3    Mabilia, M.4    Pozzan, A.5    Zunino, F.6
  • 13
    • 0028304459 scopus 로고
    • Influence of structural modifications at the 3′ and 4′ positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance
    • Capranico G, Supino R, Binaschi M, Capolongo L, Grandi M, Suarato A and Zunino F (1994b) Influence of structural modifications at the 3′ and 4′ positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance. Mol Pharmacol 45:908-915.
    • (1994) Mol Pharmacol , vol.45 , pp. 908-915
    • Capranico, G.1    Supino, R.2    Binaschi, M.3    Capolongo, L.4    Grandi, M.5    Suarato, A.6    Zunino, F.7
  • 14
    • 0025037693 scopus 로고
    • Sequence-selective topoisomerase II inhibition by anthracycline derivatives in SV40 DNA: Relationship with DNA binding affinity and cytotoxicity
    • Capranico G, Zunino F, Kohn KW and Pommier Y (1990) Sequence-selective topoisomerase II inhibition by anthracycline derivatives in SV40 DNA: Relationship with DNA binding affinity and cytotoxicity. Biochemistry 29:562-569.
    • (1990) Biochemistry , vol.29 , pp. 562-569
    • Capranico, G.1    Zunino, F.2    Kohn, K.W.3    Pommier, Y.4
  • 15
    • 0030448769 scopus 로고    scopus 로고
    • Drug sensitivity and sequence specificity of human recombinant DNA topoisomerase IIα (p170) and IIβ (p180)
    • Cornarotti M, Tinelli S, Willmore E, Zunino F, Fisher LM, Austin CA and Capranico G (1996) Drug sensitivity and sequence specificity of human recombinant DNA topoisomerase IIα (p170) and IIβ (p180). Mol Pharmacol 50:1463-1471.
    • (1996) Mol Pharmacol , vol.50 , pp. 1463-1471
    • Cornarotti, M.1    Tinelli, S.2    Willmore, E.3    Zunino, F.4    Fisher, L.M.5    Austin, C.A.6    Capranico, G.7
  • 16
    • 0025159455 scopus 로고
    • Evidence of DNA topoisomerase II-dependent mechanisms of multidrug resistance in P388 leukemia cells
    • De Isabella P, Capranico G, Binaschi M, Tinelli S and Zunino F (1990) Evidence of DNA topoisomerase II-dependent mechanisms of multidrug resistance in P388 leukemia cells. Mol Pharmacol 37:11-16.
    • (1990) Mol Pharmacol , vol.37 , pp. 11-16
    • De Isabella, P.1    Capranico, G.2    Binaschi, M.3    Tinelli, S.4    Zunino, F.5
  • 17
    • 0032543518 scopus 로고    scopus 로고
    • Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin
    • Fan Y, Weinstein JN, Kohn KW, Shi LM and Pommier Y (1998) Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin. J Med Chem 41:2216-2226.
    • (1998) J Med Chem , vol.41 , pp. 2216-2226
    • Fan, Y.1    Weinstein, J.N.2    Kohn, K.W.3    Shi, L.M.4    Pommier, Y.5
  • 18
    • 0028007482 scopus 로고
    • Localization of an aminoacridine antitumor agent in a type II topoisomerase-DNA complex
    • Freudenreich CH and Kreuzer KN (1994) Localization of an aminoacridine antitumor agent in a type II topoisomerase-DNA complex. Proc Natl Acad Sci USA 91:11007-11011.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11007-11011
    • Freudenreich, C.H.1    Kreuzer, K.N.2
  • 19
    • 0029144134 scopus 로고
    • Topoisomerase poisons: Harnessing the dark side of enzyme mechanism
    • Froelich-Ammon SJ and Osheroff N (1995) Topoisomerase poisons: Harnessing the dark side of enzyme mechanism. J Biol Chem 270:21429-21432.
    • (1995) J Biol Chem , vol.270 , pp. 21429-21432
    • Froelich-Ammon, S.J.1    Osheroff, N.2
  • 21
    • 0025037336 scopus 로고
    • Irreversible trapping of the DNA-topoisomerase I covalent complex. Affinity labeling of the camptothecin binding site
    • Hertzberg RP, Busby RW, Caranfa MJ, Holden KG, Johnson RK, Hecht SM and Kingsbury WD (1990) Irreversible trapping of the DNA-topoisomerase I covalent complex. Affinity labeling of the camptothecin binding site. J Biol Chem 265: 19287-19295.
    • (1990) J Biol Chem , vol.265 , pp. 19287-19295
    • Hertzberg, R.P.1    Busby, R.W.2    Caranfa, M.J.3    Holden, K.G.4    Johnson, R.K.5    Hecht, S.M.6    Kingsbury, W.D.7
  • 22
    • 0024324205 scopus 로고
    • On the mechanism of topoisomerase I inhibition by camptothecin: Evidence for binding to an enzyme-DNA complex
    • Hertzberg RP, Caranfa MJ and Hecht SM (1989) On the mechanism of topoisomerase I inhibition by camptothecin: Evidence for binding to an enzyme-DNA complex. Biochemistry 28:4629-4638.
    • (1989) Biochemistry , vol.28 , pp. 4629-4638
    • Hertzberg, R.P.1    Caranfa, M.J.2    Hecht, S.M.3
  • 23
    • 0025719903 scopus 로고
    • Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin
    • Jaxel C, Capranico G, Kerrigan D, Kohn KW and Pommier Y (1991) Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin. J Biol Chem 266:20418-20423.
    • (1991) J Biol Chem , vol.266 , pp. 20418-20423
    • Jaxel, C.1    Capranico, G.2    Kerrigan, D.3    Kohn, K.W.4    Pommier, Y.5
  • 25
    • 0029998477 scopus 로고    scopus 로고
    • Coralyne and related compounds as mammalian topoisomerase i and topoisomerase II poisons
    • Makhey D, Gatto B, Yu C, Liu A, Liu LF and LaVoie EJ (1996) Coralyne and related compounds as mammalian topoisomerase I and topoisomerase II poisons. Bioorg Med Chem 4:781-791.
    • (1996) Bioorg Med Chem , vol.4 , pp. 781-791
    • Makhey, D.1    Gatto, B.2    Yu, C.3    Liu, A.4    Liu, L.F.5    LaVoie, E.J.6
  • 26
    • 0031014248 scopus 로고    scopus 로고
    • Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2 beta construct allows the study of topoisomerase II beta inhibitors in yeast
    • Meczes EL, Marsh KL, Fisher LM, Rogers MP and Austin CA (1997) Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2 beta construct allows the study of topoisomerase II beta inhibitors in yeast. Cancer Chemother Pharmacol 39:367-375.
    • (1997) Cancer Chemother Pharmacol , vol.39 , pp. 367-375
    • Meczes, E.L.1    Marsh, K.L.2    Fisher, L.M.3    Rogers, M.P.4    Austin, C.A.5
  • 27
    • 0028129832 scopus 로고
    • Molecular interactions of DNA-topoisomerase I and II inhibitor with DNA and topoisomerases and in ternary complexes: Binding modes and biological effects for intoplicine derivatives
    • Nabiev I, Chourpa I, Riou JF, Nguyen CH, Lavelle F and Manfait M (1994) Molecular interactions of DNA-topoisomerase I and II inhibitor with DNA and topoisomerases and in ternary complexes: Binding modes and biological effects for intoplicine derivatives. Biochemistry 33:9013-9023.
    • (1994) Biochemistry , vol.33 , pp. 9013-9023
    • Nabiev, I.1    Chourpa, I.2    Riou, J.F.3    Nguyen, C.H.4    Lavelle, F.5    Manfait, M.6
  • 28
    • 0000536643 scopus 로고
    • DNA topoisomerase-targeting antitumor drugs can be studied in yeast
    • Nitiss J and Wang JC (1988) DNA topoisomerase-targeting antitumor drugs can be studied in yeast. Proc Natl Acad Sci USA 85:7501-7505.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7501-7505
    • Nitiss, J.1    Wang, J.C.2
  • 29
    • 0028070579 scopus 로고
    • Using yeast to study resistance to topoisomerase II-targeting drugs
    • Nitiss JL (1994) Using yeast to study resistance to topoisomerase II-targeting drugs. Cancer Chemother Pharmacol 34(Suppl):S6-S13.
    • (1994) Cancer Chemother Pharmacol , vol.34 , Issue.SUPPL.
    • Nitiss, J.L.1
  • 30
    • 0026794617 scopus 로고
    • Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II
    • Nitiss JL, Liu YX, Harbury P, Jannatipour M, Wasserman R and Wang JC (1992) Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topoisomerase II. Cancer Res 52:4467-4472.
    • (1992) Cancer Res , vol.52 , pp. 4467-4472
    • Nitiss, J.L.1    Liu, Y.X.2    Harbury, P.3    Jannatipour, M.4    Wasserman, R.5    Wang, J.C.6
  • 31
    • 0027402476 scopus 로고
    • A temperature sensitive topoisomerase II allele confers temperature dependent drug resistance on amsacrine and etoposide: A genetic system for determining the targets of topoisomerase II inhibitors
    • Nitiss JL, Liu YX and Hsiung Y (1993) A temperature sensitive topoisomerase II allele confers temperature dependent drug resistance on amsacrine and etoposide: A genetic system for determining the targets of topoisomerase II inhibitors. Cancer Res 53:89-93.
    • (1993) Cancer Res , vol.53 , pp. 89-93
    • Nitiss, J.L.1    Liu, Y.X.2    Hsiung, Y.3
  • 32
    • 0030827993 scopus 로고    scopus 로고
    • Aclacinomycin A stabilizes topoisomerase I covalent complex
    • Nitiss JL, Pourquier P and Pommier Y (1997) Aclacinomycin A stabilizes topoisomerase I covalent complex. Cancer Res 57:4564-4569.
    • (1997) Cancer Res , vol.57 , pp. 4564-4569
    • Nitiss, J.L.1    Pourquier, P.2    Pommier, Y.3
  • 33
    • 0032478137 scopus 로고    scopus 로고
    • The bis(naphthalimide) DMP-840 causes cytotoxicity by its action against eukaryotic topoisomerase II
    • Nitiss JL, Zhou J, Rose A, Hsiung Y, Gale KC and Osheroff N (1998) The bis(naphthalimide) DMP-840 causes cytotoxicity by its action against eukaryotic topoisomerase II. Biochemistry 37:3078-3085.
    • (1998) Biochemistry , vol.37 , pp. 3078-3085
    • Nitiss, J.L.1    Zhou, J.2    Rose, A.3    Hsiung, Y.4    Gale, K.C.5    Osheroff, N.6
  • 34
    • 0027484629 scopus 로고
    • Dual topoisomerase I and II inhibition by intoplicine (RP-60475), a new antitumor agent in early clinical trials
    • Poddevin B, Riou J-F, Lavelle F and Pommier Y (1993) Dual topoisomerase I and II inhibition by intoplicine (RP-60475), a new antitumor agent in early clinical trials. Mol Pharmacol 44:767-774.
    • (1993) Mol Pharmacol , vol.44 , pp. 767-774
    • Poddevin, B.1    Riou, J.-F.2    Lavelle, F.3    Pommier, Y.4
  • 35
    • 0029081258 scopus 로고
    • Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites
    • Pommier Y, Kohlhagen G, Kohn KW, Leteurtre F, Wani MC and Wall ME (1995) Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites. Proc Natl Acad Sci USA 92:8861-8865.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8861-8865
    • Pommier, Y.1    Kohlhagen, G.2    Kohn, K.W.3    Leteurtre, F.4    Wani, M.C.5    Wall, M.E.6
  • 36
    • 0030698003 scopus 로고    scopus 로고
    • Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects
    • Pourquier P, Pilon AA, Kohlhagen G, Mazumder A, Sharma A and Pommier Y (1997) Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects. J Biol Chem 272:26441-26447.
    • (1997) J Biol Chem , vol.272 , pp. 26441-26447
    • Pourquier, P.1    Pilon, A.A.2    Kohlhagen, G.3    Mazumder, A.4    Sharma, A.5    Pommier, Y.6
  • 37
    • 0032489634 scopus 로고    scopus 로고
    • Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA
    • Redinbo MR, Stewart L, Kuhn P, Champoux JJ and Hol WG (1998) Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science (Wash DC) 279:1504-1513.
    • (1998) Science (Wash DC) , vol.279 , pp. 1504-1513
    • Redinbo, M.R.1    Stewart, L.2    Kuhn, P.3    Champoux, J.J.4    Hol, W.G.5
  • 38
    • 0024533317 scopus 로고
    • Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes
    • Shen LL, Kohlbrenner WE, Weigl D and Baranowski J (1989) Mechanism of quinolone inhibition of DNA gyrase. Appearance of unique norfloxacin binding sites in enzyme-DNA complexes. J Biol Chem 264:2973-2978.
    • (1989) J Biol Chem , vol.264 , pp. 2973-2978
    • Shen, L.L.1    Kohlbrenner, W.E.2    Weigl, D.3    Baranowski, J.4
  • 39
    • 0030836293 scopus 로고    scopus 로고
    • Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar
    • Sim SP, Gatto B, Yu C, Liu AA, Li TK, Pilch DS, LaVoie EJ and Liu LF (1997) Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar. Biochemistry 36:13285-13291.
    • (1997) Biochemistry , vol.36 , pp. 13285-13291
    • Sim, S.P.1    Gatto, B.2    Yu, C.3    Liu, A.A.4    Li, T.K.5    Pilch, D.S.6    LaVoie, E.J.7    Liu, L.F.8
  • 40
    • 0023971164 scopus 로고
    • Stabilization of type I topoisomerase-DNA covalent complexes by actinomycin D
    • Trask DK and Muller MT (1988) Stabilization of type I topoisomerase-DNA covalent complexes by actinomycin D. Proc Natl Acad Sci USA 85:1417-1421.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1417-1421
    • Trask, D.K.1    Muller, M.T.2
  • 41
    • 0025303197 scopus 로고
    • Effects of morpholinyl doxorubicins, doxorubicin, and actinomycin D on mammalian DNA topoisomerases I and II
    • Wassermann K, Markovits J, Janel C, Capranico G, Kohn KW and Pommier Y (1990) Effects of morpholinyl doxorubicins, doxorubicin, and actinomycin D on mammalian DNA topoisomerases I and II. Mol Pharmacol 38:38-45.
    • (1990) Mol Pharmacol , vol.38 , pp. 38-45
    • Wassermann, K.1    Markovits, J.2    Janel, C.3    Capranico, G.4    Kohn, K.W.5    Pommier, Y.6
  • 42
    • 0027275284 scopus 로고
    • Use of yeast in the study of anticancer drugs targeting DNA topoisomerases: Expression of a functional recombinant human DNA topoisomerase IIa in yeast
    • Wasserman RA, Austin CA, Fisher LM and Wang JC (1993) Use of yeast in the study of anticancer drugs targeting DNA topoisomerases: Expression of a functional recombinant human DNA topoisomerase IIa in yeast. Cancer Res 53:3591-3596.
    • (1993) Cancer Res , vol.53 , pp. 3591-3596
    • Wasserman, R.A.1    Austin, C.A.2    Fisher, L.M.3    Wang, J.C.4


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