Differential distribution of the glutamate transporters GLT1 and rEAAC1 in rat cerebral cortex and thalamus: An in situ hybridization analysis

Anatomy and Embryology

Volumn 195, Issue 4, 1997, Pages 317-326

  Torp, R ^a   Hoover, F ^a   Danbolt, N C ^a   Storm Mathisen, J ^a   Ottersen, O P ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

GAD 65; Glia; Glutamate transporters; Non autoradiographic in situ hybridization; Riboprobes

Indexed keywords

CARRIER PROTEIN; GLUTAMIC ACID; MESSENGER RNA;

AMINO ACID TRANSPORT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; CELL TYPE; ENTORHINAL CORTEX; GENE EXPRESSION; GLIA; HIPPOCAMPUS; IN SITU HYBRIDIZATION; MALE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RNA PROBE; SUBICULUM; THALAMUS; THALAMUS NUCLEUS; TISSUE DISTRIBUTION;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; CARRIER PROTEINS; CEREBRAL CORTEX; EXCITATORY AMINO ACID TRANSPORTER 3; GLUCOSE TRANSPORTER TYPE 1; GLUTAMATE PLASMA MEMBRANE TRANSPORT PROTEINS; GLUTAMATES; IN SITU HYBRIDIZATION; MALE; MONOSACCHARIDE TRANSPORT PROTEINS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; RNA PROBES; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; SYMPORTERS; THALAMUS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0030902855     PISSN: 03402061     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004290050051     Document Type: Article

References (40)

1. Barbour B, Keller BU, Llano I, Marty A (1994) Prolonged presence of glutamate during excitatory synaptic transmission to cerebellar Purkinje cells. Neuron 12: 1331-1343
2. Bjør̊s M, Gjesdal O, Erickson JD, Torp R, Levy LM, Ottersen OP, Degree M, Storm-Mathisen J, Seeberg E, Danbolt NC (1996) Cloning and expression of neuronal rat brain glutamate transporter. Brain Res Mol Brain Res 36: 163-168
3. Carlsson M, Carlsson A (1990) Interactions between glutamatergic and monoaminergic systems within the basal ganglia - implications for schizophrenia and Parkinson's disease. Trends Neurosci 13: 272-276
4. Casado M, Bendahan A, Zafra F, Danbolt NC, Aragon C, Gimenez C, Kanner BI (1993) Phosphorylation and modulation of brain glutamate transporters by protein kinase C. J Biol Chem 268: 27313-27317
5. Chaudhry FA, Lehre KP, Lookeren Campagne M van, Ottersen OP, Danbolt NC Storm Mathisen J (1995) Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry. Neuron 15: 711-720
6. Danbolt NC (1994) The high affinity uptake system for excitatory amino acids in the brain. Prog Neurobiol 44: 377-396
7. During MJ, Spencer DD (1993) Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet 341: 1607-10
8. Esclapez M, Tillakaratne NJ, Tobin AJ, Houser CR (1993) Comparative localization of mRNAs encoding two forms of glutamic acid decarboxylase with nonradioactive in situ hybridization methods. J Comp Neurol 331: 339-362
9. 3H]aspartate loaded gel particles permits restricted uptake sites for transmitter-selective axonal transport. Exp Brain Res 63:620-626
10. Fonnum F (1984) Glutamate: a neurotransmitter in mammalian brain. J Neurochem 42: 1-11
11. Gundersen V, Danbolt NC, Ottersen OP, Storm-Mathisen J (1993) Demonstration of glutamate/aspartate uptake activity in nerve endings by use of antibodies recognizing exogenous D-aspartate. Neuroscience 57: 97-111
12. Haug FM (1976) Sulphide silver pattern and cytoarchitectonics of parahippocampal areas in the rat. Special reference to the subdivision of area entorhinalis (area 28) and its demarcation from the pyriform cortex. Adv Anat Embryol Cell Biol 52: 3-73
13. Hoover F, Goldman D (1992) Temporally correlated expression of the nAChR genes during development of the mammalian retina. Exp Eye Res 54: 561-571
14. Johnson RR, Burkhalter A (1992) Evidence for excitatory amino acid neurotransmitters in the geniculo-cortical pathway and local projections within rat primary visual cortex. Exp Brain Res 89: 20-30
15. Kanai Y, Hediger A (1992) Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360: 467-471
16. Kanai Y, Bhide PG, Difiglia M Hediger MA (1995) Neuronal high-affinity glutamate transport in the rat central nervous system. Neuroreport 6: 2357-2362
17. Kanner BI (1993) Glutamate transporters from brain. A novel neurotransmitter transporter family. FEBS Lett 325:95-9
18. Lehre KP, Levy LM, Ottersen OP, Storm-Mathisen J, Danbolt NC (1995) Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations, J Neurosci 15: 1835-1853
19. Levy LM, Lehre KP, Walaas SI, Storm-Mathisen J, Danholt NC (1995) Down-regulation of glial glutamate transporters after glutumatergic denervalion in the rat brain. Eur J Neurosci 7: 2036-2041
20. Mennerick S, Zorumski CF (1994) Glial contributions to excitatory neurotransmission in cultured hippocampal cells. Nature 368: 59-62
21. 3H] aspartate in thalamocortical neurones. Neurosci Lett 42: 19-24
22. Ottersen OP, Hjelle OP, Osen KK Laake J (1995) Amino acid transmitlers. In: Paxinos G (ed) The rat nervous system, 2nd edn. Academic Press, New York London pp 1017-1037
23. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates. 2nd edn. Academic Press, San Diego
24. Pines G, Danholt NC, Bjtiras M, Zhang Y, Bendahan A, Fide L, Koepsell H, Storm-Mathisen J, Seeberg E, Kanner BI (1992) Cloning and expression of a rat brain L-glutamate transporter. Nature 360: 464-467
25. Riederer P, Lange KW, Youdim MB (1993) Recent advances in pharmacological therapy of Parkinson's disease. Adv Neurol 60: 626-35
26. Rothstein JD, Martin L, Levey AI, Dykes-Hoberg M, Jin L, Wu D, Nash N, Kuncl RW (1994) Localization of neuronal and glial glutamate transporters. Neuron 13: 713-725
27. Rothstein JD, Van Kammen M, Levey AI, Martin LJ, Kuncl RW (1995) Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann Neurol 38: 73-84
28. Rothstein JD, Dykes-Hoberg M, Pardo CA, Bristol LA, Jin L, Kuncl RW, Kanai Y, Hediger MA, Wang Y, Schielke JP, Welly DF (1996) Knockout of glutamate transporters reveals a major role tor astroglial transport in excitotoxieity and clearance or glutamate. Neuron 16: 675-686
29. Schmitt A, Asan E, Püschel B, Jöns T, Kugler P (1996)Expression of the glutamate transporter GLT1 in neural cells of the rat central nervous system: non-radioactive in situ hybridization and comparative immunocytochemistry. Neuroscience 71: 989-1004
30. +-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci USA 89: 10955-10939
31. 3H]glutamic acid in excitatory nerve endings: light and electronmicroscopic observations in the hippocampal formation of the rat. Neuroscience 4: 1237-1253
32. Streit P (1980) Selective retrograde labeling indicating the transmitter of neuronal pathways. J Comp Neurol 191: 429-463
33. Takahashi M, Billups B, Sarantis M, Attwell D (1995a) KPSC Shaping, and glutamate release in ischaemia, by glutamate uptake carriers. Soc Neurosci 21: 730-31
34. Takahashi M, Kovalchuk Y Attwell D (1995b) Pre- and postsynaptic determinants of EPSC waveform at cerebellar climbing fiber and parallel fiber to Purkinje cell synapses. J Neurosci 15: 5693-5702
35. Taxi T, Storm-Mathisen J (1984) Uptake of D-aspartate and L-glutamate in excitatory axon terminals in hippocampus: autoradiographic and biochemical comparison with gamma-amino-butyrate and other aminci acids in normal rats and in rats with lesions. Neuroscience 11: 79-100
36. Tong G, Jahr CE (1994) Block of glutamate transporters potentiates postsynaptic excitation. Neuron 13: 1195-1203
37. Torp R, Danbolt NC, Babaie E, Bjørås M, Seeberg E, StormMathisen J, Oltersen OP (1994) Differential expression of two glial glutamate transporters in the rat brain: an in situ hybridization study. Eur J Neurosci 6: 936-942
38. Trotti D, Volterra A, Lehre KP, Rossi D, Gjesdal O, Racagni G, Danbolt NC (1995) Arachidonic acid inhibits a purified and reconstituted glutamate transporter directly from the water phase and not via the phospholipid membrane. J Biol Chem 270: 9890-9895
39. Tsumoto T (1990) Excitatory amino acid transmitters and their receptors in neural circuits of the cerebral neocortex. Neurosci Res 9: 79-102
40. Velaz-Eaircloth M, McGraw TS, Malandro MS, Fremeau RT, Kilherg MS, Anderson KJ (1996) Characlerization and distribution of the neuronal glutamate transporter EAAC1 in rat brain. Am J Physiol Cell Physiol 39: C67-C75