Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity

Nature Genetics

Volumn 25, Issue 4, 2000, Pages 385-389

  Li, He ^a,b   Li, Shi Hua ^a   Johnston, Heather ^c   Shelbourne, Peggy F ^c   Li, Xiao Jiang ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMINE; HUNTINGTIN; MUTANT PROTEIN;

AMINO ACID TRANSPORT; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CELL NUCLEUS; CONTROLLED STUDY; CORPUS STRIATUM; GENE MUTATION; HUNTINGTON CHOREA; IN VITRO STUDY; MOUSE; NERVE ENDING; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROCESSING; RAT; SYNAPSE VESICLE;

ANIMALS; CORPUS STRIATUM; MICE; MICE, MUTANT STRAINS; MUTATION; NERVE TISSUE PROTEINS; NEURITES; NEURONS; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; PEPTIDES; RATS; RECOMBINANT FUSION PROTEINS; SYNAPTIC VESICLES;

ANIMALIA;

EID: 0034426013     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/78054     Document Type: Article

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