-
1
-
-
0000481827
-
Bcr-Abl-mediated resistance to apoptosis is independent of PI 3-kinase activity
-
Amarante-Mendes GP, Jascur T, Nishioka WK, Mustelin T and Green DR (1997) Bcr-Abl-mediated resistance to apoptosis is independent of PI 3-kinase activity. Cell Death Differ. 4: 548-554
-
(1997)
Cell Death Differ.
, vol.4
, pp. 548-554
-
-
Amarante-Mendes, G.P.1
Jascur, T.2
Nishioka, W.K.3
Mustelin, T.4
Green, D.R.5
-
3
-
-
0032472329
-
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane potential
-
in press
-
Bossy-Wetzel E, Newmeyer DD and Green DR. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane potential EMBO J, in press
-
EMBO J
-
-
Bossy-Wetzel, E.1
Newmeyer, D.D.2
Green, D.R.3
-
4
-
-
0030134624
-
The cell-death machine
-
Chinnaiyan A and Dixit V (1996) The cell-death machine. Curr. Biol. 6: 555-562
-
(1996)
Curr. Biol.
, vol.6
, pp. 555-562
-
-
Chinnaiyan, A.1
Dixit, V.2
-
5
-
-
0029912189
-
Molecular ordering of the cell death pathway: Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptosis proteases
-
Chinnaiyan AM, Orth K, O'Rourke K, Duan H, Poirier GG and Dixit VM (1996) Molecular ordering of the cell death pathway: Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptosis proteases. J Biol. Chem. 271: 4573-4576
-
(1996)
J Biol. Chem.
, vol.271
, pp. 4573-4576
-
-
Chinnaiyan, A.M.1
Orth, K.2
O'Rourke, K.3
Duan, H.4
Poirier, G.G.5
Dixit, V.M.6
-
6
-
-
0022497852
-
Genetic control of programmed cell death in the nematode C. elegans
-
Ellis HM and Horvitz HR (1986) Genetic control of programmed cell death in the nematode C. elegans Cell 44. 817-829
-
(1986)
Cell
, vol.44
, pp. 817-829
-
-
Ellis, H.M.1
Horvitz, H.R.2
-
8
-
-
0029995766
-
A licence to kill
-
Fraser A and Evan G (1996) A licence to kill. Cell 85: 781-784
-
(1996)
Cell
, vol.85
, pp. 781-784
-
-
Fraser, A.1
Evan, G.2
-
9
-
-
0028789425
-
The killer and the executioner: How apoptosis controls malignancy
-
Green DR and Martin SJ (1995) The killer and the executioner: how apoptosis controls malignancy. Curr. Opin Immunol. 7: 694-703
-
(1995)
Curr. Opin Immunol.
, vol.7
, pp. 694-703
-
-
Green, D.R.1
Martin, S.J.2
-
10
-
-
0029161958
-
The head involution defective gene of Drosophila melanogaster functions in programmed cell death
-
Grether ME, Abrams JM, Agapite J, White K and Steller H (1995) The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev. 9: 1694-1708
-
(1995)
Genes Dev.
, vol.9
, pp. 1694-1708
-
-
Grether, M.E.1
Abrams, J.M.2
Agapite, J.3
White, K.4
Steller, H.5
-
11
-
-
0029664296
-
ICE family proteases. mediators of all apoptotic cell death?
-
Henkart PA (1996) ICE family proteases. mediators of all apoptotic cell death? Immunity 4: 195-201
-
(1996)
Immunity
, vol.4
, pp. 195-201
-
-
Henkart, P.A.1
-
12
-
-
0029958864
-
Apoptosis. mitochondria resurrected?
-
Henkart PA and Grinstein S (1996) Apoptosis. mitochondria resurrected? J. Exp. Med. 183: 1293-1295
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1293-1295
-
-
Henkart, P.A.1
Grinstein, S.2
-
13
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
Kluck RM, Bossy-Wetzel E, Green DR and Newmeyer DD (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275: 1132-1136
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
14
-
-
0029956641
-
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
-
Kuida K, Zheng TS, Na S, Kuan C-Y, Yang D, Karasuyama H, Rakic P and Flavell RA (1996) Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384: 368-372
-
(1996)
Nature
, vol.384
, pp. 368-372
-
-
Kuida, K.1
Zheng, T.S.2
Na, S.3
Kuan, C.-Y.4
Yang, D.5
Karasuyama, H.6
Rakic, P.7
Flavell, R.A.8
-
15
-
-
0029794385
-
The ICE family of cysteine proteases as effector of cell death
-
Kumar S and Lavin MF (1996) The ICE family of cysteine proteases as effector of cell death Cell Death Differ. 3. 255-267
-
(1996)
Cell Death Differ.
, vol.3
, pp. 255-267
-
-
Kumar, S.1
Lavin, M.F.2
-
16
-
-
0029773397
-
An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat
-
Loddick CA, MacKenzie A and Rothwell NJ (1996) An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat. Neuroreport 7: 1465-1468
-
(1996)
Neuroreport
, vol.7
, pp. 1465-1468
-
-
Loddick, C.A.1
MacKenzie, A.2
Rothwell, N.J.3
-
17
-
-
0031009716
-
Caspase activity is required for commitment to Fas-mediated apoptosis
-
Longthome VL and Williams GT (1997) Caspase activity is required for commitment to Fas-mediated apoptosis. EMBO J. 16: 3805-3812
-
(1997)
EMBO J.
, vol.16
, pp. 3805-3812
-
-
Longthome, V.L.1
Williams, G.T.2
-
18
-
-
9544246860
-
Mitochondrial permeability transition is a central coordinating event of apoptosts
-
Marchetti P, Castedo M, Susin SA, Zamzami N, Hirsch T, Macho A, Haeffner A, Hirsch F, Geuskens M and Kroemer G (1996) Mitochondrial permeability transition is a central coordinating event of apoptosts. J Exp. Med. 184: 1155-1160
-
(1996)
J Exp. Med.
, vol.184
, pp. 1155-1160
-
-
Marchetti, P.1
Castedo, M.2
Susin, S.A.3
Zamzami, N.4
Hirsch, T.5
Macho, A.6
Haeffner, A.7
Hirsch, F.8
Geuskens, M.9
Kroemer, G.10
-
19
-
-
9344261615
-
The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism
-
Martin SJ, Amarante-Mendes GP, Shi L, Chuang TH, Casiano CA, O'Brien GA, Fitzgerald P, Tan EM, Bokoch GM, Greenberg AH and Green DR (1996) The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism. EMBO J. 15: 2407-2416
-
(1996)
EMBO J.
, vol.15
, pp. 2407-2416
-
-
Martin, S.J.1
Amarante-Mendes, G.P.2
Shi, L.3
Chuang, T.H.4
Casiano, C.A.5
O'Brien, G.A.6
Fitzgerald, P.7
Tan, E.M.8
Bokoch, G.M.9
Greenberg, A.H.10
Green, D.R.11
-
20
-
-
0029125701
-
Protease activation during apoptosis: Death by a thousand cuts?
-
Martin SJ and Green DR (1995) Protease activation during apoptosis: death by a thousand cuts? Cell 82: 349-352
-
(1995)
Cell
, vol.82
, pp. 349-352
-
-
Martin, S.J.1
Green, D.R.2
-
21
-
-
0028800947
-
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
-
Martin SJ, Reutelingsperger CPM, McGahon AJ, Rader J, van Schie RCAA, LaFace DM and Green DR (1995a) Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl J. Exp. Med. 182: 1-12
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1-12
-
-
Martin, S.J.1
Reutelingsperger, C.P.M.2
McGahon, A.J.3
Rader, J.4
Van Schie, R.C.A.A.5
LaFace, D.M.6
Green, D.R.7
-
22
-
-
0028851406
-
Inhibition of ceramide-induced apoptosis by Bcl-2
-
Martin SJ, Takayama S, McGahon AJ, MiyashitaT, Corbeil J, Kolesnick RN, Reed JC and Green DR (1995b) Inhibition of ceramide-induced apoptosis by Bcl-2. Cell Death Differ. 2. 253-257
-
(1995)
Cell Death Differ.
, vol.2
, pp. 253-257
-
-
Martin, S.J.1
Takayama, S.2
McGahon, A.J.3
MiyashitaT4
Corbeil, J.5
Kolesnick, R.N.6
Reed, J.C.7
Green, D.R.8
-
23
-
-
0031033274
-
Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak
-
McCarthy NJ, Whyte MKB, Gilbert CS and Evan GI (1997) Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J. Cell Biol. 136: 215-227
-
(1997)
J. Cell Biol.
, vol.136
, pp. 215-227
-
-
McCarthy, N.J.1
Whyte, M.K.B.2
Gilbert, C.S.3
Evan, G.I.4
-
24
-
-
0029199452
-
The end of the (cell) line: Methods for the study of apoptosis in vitro
-
LM Schwartz and BA Osbome, (eds) (San Diego: Academic Press, Inc.)
-
McGahon AJ, Martin SJ, Mahboubi A, Bissonette RP, Shi Y, Mogil R, Nishioka W and Green DR (1995) The end of the (cell) line: Methods for the study of apoptosis in vitro. In Cell Death, LM Schwartz and BA Osbome, (eds) (San Diego: Academic Press, Inc.), pp 153-186
-
(1995)
Cell Death
, pp. 153-186
-
-
McGahon, A.J.1
Martin, S.J.2
Mahboubi, A.3
Bissonette, R.P.4
Shi, Y.5
Mogil, R.6
Nishioka, W.7
Green, D.R.8
-
25
-
-
1842332735
-
Bcl-x(L) forms an ion channelin synthetic lipid membranes
-
Minn AJ, Velez P, Schendel SL, Liang H, Muchmore SW, Fesik SW, Fill M and Thompson CB (1997) Bcl-x(L) forms an ion channelin synthetic lipid membranes. Nature 385. 353-357
-
(1997)
Nature
, vol.385
, pp. 353-357
-
-
Minn, A.J.1
Velez, P.2
Schendel, S.L.3
Liang, H.4
Muchmore, S.W.5
Fesik, S.W.6
Fill, M.7
Thompson, C.B.8
-
26
-
-
5244224827
-
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
-
Muchmore SW, Sattler M, Liang H, Meadows RP, Harlan JE, Yoon HS, Nettesheim D, Chang BS, Thompson CB, Wong SL, Ng S-C and Fesik SW (1996) X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature 381. 335-341
-
(1996)
Nature
, vol.381
, pp. 335-341
-
-
Muchmore, S.W.1
Sattler, M.2
Liang, H.3
Meadows, R.P.4
Harlan, J.E.5
Yoon, H.S.6
Nettesheim, D.7
Chang, B.S.8
Thompson, C.B.9
Wong, S.L.10
Ng, S.-C.11
Fesik, S.W.12
-
27
-
-
0025726216
-
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
-
Nicoletti I, Migliorati G, Pagliacci MC, Grignani F and Riccardi C (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immun. Meth. 139: 271-279
-
(1991)
J. Immun. Meth.
, vol.139
, pp. 271-279
-
-
Nicoletti, I.1
Migliorati, G.2
Pagliacci, M.C.3
Grignani, F.4
Riccardi, C.5
-
28
-
-
0030602011
-
Activation of the reaper gene during ectopic cell killing in Drosophila
-
Nordstrom W, Chen P, Steller H and Abrams JM (1996) Activation of the reaper gene during ectopic cell killing in Drosophila. Dev Biol 180: 213-226
-
(1996)
Dev Biol
, vol.180
, pp. 213-226
-
-
Nordstrom, W.1
Chen, P.2
Steller, H.3
Abrams, J.M.4
-
29
-
-
0029036412
-
Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis
-
Petit PX, Lecoeur H, Zorn E, Dauguet C, Mignotte B and Gougeon ML (1995) Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J. Cell Biol. 130: 157-167
-
(1995)
J. Cell Biol.
, vol.130
, pp. 157-167
-
-
Petit, P.X.1
Lecoeur, H.2
Zorn, E.3
Dauguet, C.4
Mignotte, B.5
Gougeon, M.L.6
-
30
-
-
0031008397
-
Channel Formation by Anti-Apoptotic Protein, Bcl-2
-
Schendel SL, Xie Z, Montal MO, Matsuyama S, Montal M and Reed JC (1997) Channel Formation by Anti-Apoptotic Protein, Bcl-2. Proc. Natl. Acad Sci. USA. 94 5113-5118
-
(1997)
Proc. Natl. Acad Sci. USA
, vol.94
, pp. 5113-5118
-
-
Schendel, S.L.1
Xie, Z.2
Montal, M.O.3
Matsuyama, S.4
Montal, M.5
Reed, J.C.6
-
31
-
-
0029984098
-
Bcl-2 expression prevents activation of the ICE protease cascade
-
Shimizu S, Eguchi Y, Kamiike W, Matsuda H and Tsujimoto Y (1996) Bcl-2 expression prevents activation of the ICE protease cascade. Oncogene 12: 2251-2257
-
(1996)
Oncogene
, vol.12
, pp. 2251-2257
-
-
Shimizu, S.1
Eguchi, Y.2
Kamiike, W.3
Matsuda, H.4
Tsujimoto, Y.5
-
32
-
-
0029609086
-
Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
-
Strasser A, Harris AW, Huang DC, Krammer PH and Cory S (1995) Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J. 14: 6136-6147
-
(1995)
EMBO J.
, vol.14
, pp. 6136-6147
-
-
Strasser, A.1
Harris, A.W.2
Huang, D.C.3
Krammer, P.H.4
Cory, S.5
-
33
-
-
0029950290
-
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
-
Susin SA, Zamzami N, Castedo M, Hirsch T, Marchetti P, Macho A, Daugas E, Geuskens M and Kroemer G (1996) Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J. Exp. Med. 184: 1331-1341
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1331-1341
-
-
Susin, S.A.1
Zamzami, N.2
Castedo, M.3
Hirsch, T.4
Marchetti, P.5
Macho, A.6
Daugas, E.7
Geuskens, M.8
Kroemer, G.9
-
34
-
-
0028046038
-
Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40
-
Vayssiere JL, Petit PX, Risler Y and Mignotte B (1994) Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc. Natl. Acad. Sci USA 91: 11752-11756
-
(1994)
Proc. Natl. Acad. Sci USA
, vol.91
, pp. 11752-11756
-
-
Vayssiere, J.L.1
Petit, P.X.2
Risler, Y.3
Mignotte, B.4
-
35
-
-
0030021282
-
Cell killing by the Drosophila gene reaper
-
White K, Tahaoglu E and Steller H (1996) Cell killing by the Drosophila gene reaper Science 271: 805-807
-
(1996)
Science
, vol.271
, pp. 805-807
-
-
White, K.1
Tahaoglu, E.2
Steller, H.3
-
36
-
-
0029906828
-
BAX-induced cell death may not require interleukin 1β-converting enzyme-like proteases
-
Xiang J, Chao DT and Korsmeyer SJ (1996) BAX-induced cell death may not require interleukin 1β-converting enzyme-like proteases Proc. Natl. Acad Sci. USA. 93: 14559-14563
-
(1996)
Proc. Natl. Acad Sci. USA
, vol.93
, pp. 14559-14563
-
-
Xiang, J.1
Chao, D.T.2
Korsmeyer, S.J.3
-
37
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, Peng TI, Jones DP and Wang X (1997) Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275: 1129-1132
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
Peng, T.I.7
Jones, D.P.8
Wang, X.9
-
38
-
-
0028903933
-
Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
-
Zamzami N, Marchetti P, Castedo M, Zanin C, Vayssiere JL, Petit PX and Kroemer G (1995) Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med 181: 1661-1672
-
(1995)
J. Exp. Med
, vol.181
, pp. 1661-1672
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
Zanin, C.4
Vayssiere, J.L.5
Petit, P.X.6
Kroemer, G.7
|