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Volumn 52, Issue 6, 1998, Pages 248-251

The central role of the mitochondrial megachannel in apoptosis: Evidence obtained with intact cells, isolated mitochondria, and purified protein complexes

Author keywords

Mitochondrial transmembrane potential; Permeability transition; Programmed cell death; Proteases

Indexed keywords

LIPOSOME; NUCLEASE; PROTEIN; PROTEIN BCL 2; PROTEINASE;

EID: 0032127416     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0753-3322(98)80009-7     Document Type: Article
Times cited : (72)

References (31)
  • 2
    • 0001425438 scopus 로고    scopus 로고
    • The cell biology of apoptosis: Evidence for the involvement of mitochondria
    • 2 Susin SA, Zamzami N, Kroemer G. The cell biology of apoptosis: evidence for the involvement of mitochondria. Apoptosis 1996 ; 1 : 231-42
    • (1996) Apoptosis , vol.1 , pp. 231-242
    • Susin, S.A.1    Zamzami, N.2    Kroemer, G.3
  • 5
    • 0029966796 scopus 로고    scopus 로고
    • Chloromethyl-X-rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis
    • 5 Macho A, Decaudin D, Castedo M et al, Chloromethyl-X-rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. Cytometry 1996 ; 25 : 333-40
    • (1996) Cytometry , vol.25 , pp. 333-340
    • Macho, A.1    Decaudin, D.2    Castedo, M.3
  • 6
    • 0028903933 scopus 로고
    • Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
    • 6 Zamzami N, Marchetti P, Castedo M et al. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J Exp Med 1995 ; 181 : 1661-72
    • (1995) J Exp Med , vol.181 , pp. 1661-1672
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3
  • 7
    • 0029101644 scopus 로고
    • Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
    • 7 Zamzami N, Marchetti P, Castedo M et al. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 1995 ; 182 : 367-77
    • (1995) J Exp Med , vol.182 , pp. 367-377
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3
  • 8
    • 9244237035 scopus 로고    scopus 로고
    • Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA
    • 8 Marchetti P, Susin SA, Decaudin D et al. Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA. Cancer Res 1996 ; 56 : 2033-8
    • (1996) Cancer Res , vol.56 , pp. 2033-2038
    • Marchetti, P.1    Susin, S.A.2    Decaudin, D.3
  • 9
    • 0029862706 scopus 로고    scopus 로고
    • Mitochondrial control of nuclear apoptosis
    • 9 Zamzami N, Susin SA, Marchetti P et al. Mitochondrial control of nuclear apoptosis. J Exp Med 1996 ; 183 : 1533-44
    • (1996) J Exp Med , vol.183 , pp. 1533-1544
    • Zamzami, N.1    Susin, S.A.2    Marchetti, P.3
  • 10
    • 0031032294 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents
    • 10 Decaudin D, Geley S, Hirsch T et al. Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. Cancer Res 1997 ; 57 : 62-7
    • (1997) Cancer Res , vol.57 , pp. 62-67
    • Decaudin, D.1    Geley, S.2    Hirsch, T.3
  • 11
    • 0032052217 scopus 로고    scopus 로고
    • Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes
    • in press
    • 11 Metivier D, Dallaporta B, Zamzami N et al. Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes. Immunol Lett 1998 ; in press
    • (1998) Immunol Lett
    • Metivier, D.1    Dallaporta, B.2    Zamzami, N.3
  • 12
    • 0031013150 scopus 로고    scopus 로고
    • Redox regulation of apoptosis: Impact of thiol redoxidation on mitochondrial function
    • 12 Marchetti P, Decaudin D, Macho A et al. Redox regulation of apoptosis: impact of thiol redoxidation on mitochondrial function. Eur J Immunol 1997 ; 27 : 289-96
    • (1997) Eur J Immunol , vol.27 , pp. 289-296
    • Marchetti, P.1    Decaudin, D.2    Macho, A.3
  • 13
    • 0029944880 scopus 로고    scopus 로고
    • Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis
    • 13 Castedo M, Hirsch T, Susin SA et al. Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis. J Immunol 1996 ; 157 : 512-21
    • (1996) J Immunol , vol.157 , pp. 512-521
    • Castedo, M.1    Hirsch, T.2    Susin, S.A.3
  • 14
    • 0030785790 scopus 로고    scopus 로고
    • The central executioner of apoptosis. Multiple links between protease activation and mitochondria in Fas/Apo-1/CD95-and ceramide-induced apoptosis
    • 14 Susin SA, Zamzami N, Castedo M et al. The central executioner of apoptosis. Multiple links between protease activation and mitochondria in Fas/Apo-1/CD95-and ceramide-induced apoptosis. J Exp Med 1997 ; 186: 25-37
    • (1997) J Exp Med , vol.186 , pp. 25-37
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3
  • 15
    • 0032567877 scopus 로고    scopus 로고
    • The thiol-crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition
    • 15 Zamzami N, Marzo I, Susin SA et al. The thiol-crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition. Oncogene 1998 ; 16 : 1055-63
    • (1998) Oncogene , vol.16 , pp. 1055-1063
    • Zamzami, N.1    Marzo, I.2    Susin, S.A.3
  • 17
    • 0030848374 scopus 로고    scopus 로고
    • Mitochondrial implication in accidental and programmed cell death: Apoptosis and necrosis
    • 17 Zamzami N, Hirsch T, Dallaporta B, Petit PX, Kroemer G. Mitochondrial implication in accidental and programmed cell death: apoptosis and necrosis. J Bioenerg Biomembr 1997 ; 29 : 185-93
    • (1997) J Bioenerg Biomembr , vol.29 , pp. 185-193
    • Zamzami, N.1    Hirsch, T.2    Dallaporta, B.3    Petit, P.X.4    Kroemer, G.5
  • 18
    • 0031570036 scopus 로고    scopus 로고
    • Glutathione depletion is an early and calcium elevation a late event of thymocyte apoptosis
    • 18 Macho A, Hirsch T, Marzo I et al. Glutathione depletion is an early and calcium elevation a late event of thymocyte apoptosis. J Immunol 1997 ; 158 : 4612-19
    • (1997) J Immunol , vol.158 , pp. 4612-4619
    • Macho, A.1    Hirsch, T.2    Marzo, I.3
  • 20
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • 20 Kroemer G, Dallaporta B, Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 1998 ; 60 : 619-42
    • (1998) Annu Rev Physiol , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 21
    • 9544246860 scopus 로고    scopus 로고
    • Mitochondrial permeability transition is a central coordinating event of apoptosis
    • 21 Marchetti P, Castedo M, Susin SA et al. Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med 1996 ; 184 : 1155-60
    • (1996) J Exp Med , vol.184 , pp. 1155-1160
    • Marchetti, P.1    Castedo, M.2    Susin, S.A.3
  • 22
    • 0030698810 scopus 로고    scopus 로고
    • The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death
    • 22 Hirsch T, Marchetti P, Susin SA et al. The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene 1997 ; 15 : 1573-82
    • (1997) Oncogene , vol.15 , pp. 1573-1582
    • Hirsch, T.1    Marchetti, P.2    Susin, S.A.3
  • 23
    • 0030471143 scopus 로고    scopus 로고
    • Mitochondrial permeability transition triggers lymphocyte apoptosis
    • 23 Marchetti P, Hirsch T, Zamzami N et al. Mitochondrial permeability transition triggers lymphocyte apoptosis. J Immunol 1996 ; 157 : 4830-6
    • (1996) J Immunol , vol.157 , pp. 4830-4836
    • Marchetti, P.1    Hirsch, T.2    Zamzami, N.3
  • 24
    • 0029950290 scopus 로고    scopus 로고
    • Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
    • 24 Susin SA, Zamzami N, Castedo M et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 1996 ; 184 : 1331-42
    • (1996) J Exp Med , vol.184 , pp. 1331-1342
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3
  • 25
    • 0031281283 scopus 로고    scopus 로고
    • A cytofluorometric assay of nuclear apoptosis induced in a cell-free system. Application to ceramide-induced apoptosis
    • 25 Susin SA, Zamzami N, Larochette N et al. A cytofluorometric assay of nuclear apoptosis induced in a cell-free system. Application to ceramide-induced apoptosis. Exp Cell Res 1997 ; 236 : 397-403
    • (1997) Exp Cell Res , vol.236 , pp. 397-403
    • Susin, S.A.1    Zamzami, N.2    Larochette, N.3
  • 26
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • 26 Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nature Medicine 1997 ; 3 : 614-20
    • (1997) Nature Medicine , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 27
    • 0030741693 scopus 로고    scopus 로고
    • Nitric oxide induces apoptosis via triggering mitochondrial permeability transition
    • 27 Hortelano S, Dallaporta B, Zamzami N et al. Nitric oxide induces apoptosis via triggering mitochondrial permeability transition. FEBS Lett 1997 ; 410 : 373-7
    • (1997) FEBS Lett , vol.410 , pp. 373-377
    • Hortelano, S.1    Dallaporta, B.2    Zamzami, N.3
  • 28
    • 0032550363 scopus 로고    scopus 로고
    • The permeability transition pore complex: A target for apoptosis regulation by caspases and Bcl-2 related proteins
    • 28 Marzo I, Brenner C, Zamzami N et al. The permeability transition pore complex: a target for apoptosis regulation by caspases and Bcl-2 related proteins. J Exp Med 1998 ; 187 : 1261-71
    • (1998) J Exp Med , vol.187 , pp. 1261-1271
    • Marzo, I.1    Brenner, C.2    Zamzami, N.3
  • 29
    • 0032567877 scopus 로고    scopus 로고
    • Subcellular and submitochondrial mechanisms of apoptosis inhibition by Bcl-2-related proteins
    • 29 Zamzami N, Marzo I, Larochette N et al. Subcellular and submitochondrial mechanisms of apoptosis inhibition by Bcl-2-related proteins. Oncogene 1998 ; 16 : 1055-64
    • (1998) Oncogene , vol.16 , pp. 1055-1064
    • Zamzami, N.1    Marzo, I.2    Larochette, N.3
  • 30
    • 14044251695 scopus 로고    scopus 로고
    • Mitochondrial implication in apoptosis. Towards an endosymbiotic hypothesis of apoptosis evolution
    • 30 Kroemer G. Mitochondrial implication in apoptosis. Towards an endosymbiotic hypothesis of apoptosis evolution. Cell Death Differentiation 1997 ; 4 : 443-56
    • (1997) Cell Death Differentiation , vol.4 , pp. 443-456
    • Kroemer, G.1
  • 31
    • 0031980222 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of T lymphocyte apoptosis
    • 31 Penninger J, Kroemer G. Molecular and cellular mechanisms of T lymphocyte apoptosis. Adv Immunol 1998 ; 68 : 51-144
    • (1998) Adv Immunol , vol.68 , pp. 51-144
    • Penninger, J.1    Kroemer, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.