-
1
-
-
0030273295
-
Mitochondria, free radicals, and neurodegeneration
-
Beal MF (1996) Mitochondria, free radicals, and neurodegeneration. Curr Opin Neurobiol 6:661–666.
-
(1996)
Curr Opin Neurobiol
, vol.6
, pp. 661-666
-
-
Beal, M.F.1
-
2
-
-
0027289608
-
L-deprenyl increases gfap immunoreactivity selectively in activated astrocytes in rat brain
-
Biagini G, Zoli M, Fuxe K, Agnati LF (1993) L-Deprenyl increases GFAP immunoreactivity selectively in activated astrocytes in rat brain. NeuroReport 4:955–958.
-
(1993)
Neuroreport
, vol.4
, pp. 955-958
-
-
Biagini, G.1
Zoli, M.2
Fuxe, K.3
Agnati, L.F.4
-
3
-
-
0028343249
-
The concept of astrocyte-kinetic drug in the treatment of neurodegenerative diseases: Evidence for l-deprenyl-induced activation of reactive astrocytes
-
Biagini G, Frasoldati A, Fuxe K, Agnati LF (1994) The concept of astrocyte-kinetic drug in the treatment of neurodegenerative diseases: evidence for L-deprenyl-induced activation of reactive astrocytes. Neurochem Int 25:17–22.
-
(1994)
Neurochem Int
, vol.25
, pp. 17-22
-
-
Biagini, G.1
Frasoldati, A.2
Fuxe, K.3
Agnati, L.F.4
-
4
-
-
0028956188
-
Polarization of mitochondria in the fertilized mouse oocyte
-
Calarco PG (1995) Polarization of mitochondria in the fertilized mouse oocyte. Dev Genet 16:36–43.
-
(1995)
Dev Genet
, vol.16
, pp. 36-43
-
-
Calarco, P.G.1
-
5
-
-
0029915241
-
Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage
-
Carayon P, Portier M, Dussossoy D, Bord A, Petipretre G, Canat X, Le Fur G, Casellas P (1996) Involvement of peripheral benzodiazepine receptors in the protection of hematopoietic cells against oxygen radical damage. Blood 87:3170–3178.
-
(1996)
Blood
, vol.87
, pp. 3170-3178
-
-
Carayon, P.1
Portier, M.2
Dussossoy, D.3
Bord, A.4
Petipretre, G.5
Canat, X.6
Le Fur, G.7
Casellas, P.8
-
6
-
-
0029617756
-
Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo
-
Castedo M, Macho A, Zamzami N, Hirsch T, Marchetti P, Uriel J, Kroemer G (1995) Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo. Eur J Immunol 25:3277–3284.
-
(1995)
Eur J Immunol
, vol.25
, pp. 3277-3284
-
-
Castedo, M.1
Macho, A.2
Zamzami, N.3
Hirsch, T.4
Marchetti, P.5
Uriel, J.6
Kroemer, G.7
-
7
-
-
0029944880
-
Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis
-
Castedo M, Hirsch T, Susin SA, Zamzami N, Marchetti P, Macho A, Kroemer G (1996) Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis. J Immunol 157:512–521.
-
(1996)
J Immunol
, vol.157
, pp. 512-521
-
-
Castedo, M.1
Hirsch, T.2
Susin, S.A.3
Zamzami, N.4
Marchetti, P.5
Macho, A.6
Kroemer, G.7
-
8
-
-
0030638547
-
Mechanisms of nerve cell death: Apoptosis or necrosis after cerebral ischaemia
-
Green AR, Cross AJ, eds, San Diego: Academic
-
Chalmers-Redman RME, Fraser AD, Ju WYH, Wadia J, Tatton NA, Tatton WG (1997) Mechanisms of nerve cell death: apoptosis or necrosis after cerebral ischaemia. In: Neuroprotective agents and cerebral ischaemia (Green AR, Cross AJ, eds), pp 1–25. San Diego: Academic.
-
(1997)
Neuroprotective Agents and Cerebral Ischaemia
, pp. 1-25
-
-
Chalmers-Redman, R.M.E.1
Fraser, A.D.2
Ju, W.Y.H.3
Wadia, J.4
Tatton, N.A.5
Tatton, W.G.6
-
9
-
-
0028510622
-
Use of fluoresent probes to investigate the metabolic state of pneumocystis carinii mitochondria
-
Chen F, Cushion MT (1994) Use of fluoresent probes to investigate the metabolic state of Pneumocystis carinii mitochondria. J Eukaryot Microbiol 41:79S.
-
(1994)
J Eukaryot Microbiol
, vol.79S
, pp. 41
-
-
Chen, F.1
Cushion, M.T.2
-
10
-
-
0030038762
-
The mitochondrial permeability pore is modulated by oxidative agents through both pyridine nucleotides and glutathione at two separate sites
-
Chernyak BV, Bernardi P (1996) The mitochondrial permeability pore is modulated by oxidative agents through both pyridine nucleotides and glutathione at two separate sites. Eur J Biochem 238:623–630.
-
(1996)
Eur J Biochem
, vol.238
, pp. 623-630
-
-
Chernyak, B.V.1
Bernardi, P.2
-
11
-
-
0027485950
-
Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor
-
Deckwerth TL, Johnson Jr EM (1993) Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor. J Cell Biol 123:1207–1222.
-
(1993)
J Cell Biol
, vol.123
, pp. 1207-1222
-
-
Deckwerth, T.L.1
Johnson, E.M.2
-
12
-
-
0029065448
-
Mitochondrial membrane potential in single living adult rat cardiac myocytes exposed to anoxia or metabolic inhibition
-
Di Lisa F, Blank PS, Colonna R, Gambassi G, Siverman HS, Stern MD, Hansford RG (1995) Mitochondrial membrane potential in single living adult rat cardiac myocytes exposed to anoxia or metabolic inhibition. J Physiol (Lond) 486:1–13.
-
(1995)
J Physiol (Lond)
, vol.486
, pp. 1-13
-
-
Di Lisa, F.1
Blank, P.S.2
Colonna, R.3
Gambassi, G.4
Siverman, H.S.5
Stern, M.D.6
Hansford, R.G.7
-
13
-
-
0028269443
-
Aquilonius sm (1994) mrna expression of neurotrophins and members of the trk family in the rat brain after treatment with l-deprenyl
-
Ekblom J, Jossan SS, Ebendal T, Soderstrom S, Oreland L, Aquilonius SM (1994) mRNA expression of neurotrophins and members of the trk family in the rat brain after treatment with L-deprenyl. Acta Neurol Scand 89:147–148.
-
Acta Neurol Scand
, vol.89
, pp. 147-148
-
-
Ekblom, J.1
Jossan, S.S.2
Ebendal, T.3
Soderstrom, S.4
Oreland, L.5
-
14
-
-
0027221981
-
Striatal degeneration induced by mitochondrial blockade is prevented by biologically delivered ngf
-
Frim DM, Simpson J, Uhler TA, Short MP, Bossi SR, Breakfield XO, Isacson O (1993) Striatal degeneration induced by mitochondrial blockade is prevented by biologically delivered NGF. J Neurosci Res 35:452–458.
-
(1993)
J Neurosci Res
, vol.35
, pp. 452-458
-
-
Frim, D.M.1
Simpson, J.2
Uhler, T.A.3
Short, M.P.4
Bossi, S.R.5
Breakfield, X.O.6
Isacson, O.7
-
15
-
-
0000089849
-
Nerve growth factor inhibits apoptosis induced by s-100 binding in neuronal pc12 cells
-
Fulle S, Mariggio MA, Belia S, Nicoletti I, Fano G (1997) Nerve growth factor inhibits apoptosis induced by S-100 binding in neuronal PC12 cells. Neuroscience 76:159–166.
-
(1997)
Neuroscience
, vol.76
, pp. 159-166
-
-
Fulle, S.1
Mariggio, M.A.2
Belia, S.3
Nicoletti, I.4
Fano, G.5
-
16
-
-
0027513548
-
Expression of bcl-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity
-
Hennet TG, Bertoni G, Richter C, Peterhans E (1993) Expression of Bcl-2 protein enhances the survival of mouse fibrosarcoid cells in tumor necrosis factor-mediated cytotoxicity. Cancer Res 53:1456–1460.
-
(1993)
Cancer Res
, vol.53
, pp. 1456-1460
-
-
Hennet, T.G.1
Bertoni, G.2
Richter, C.3
Peterhans, E.4
-
17
-
-
0027476151
-
Bcl-2 blocks apoptosis in cells lacking mitochondrial dna
-
Jacobson MD, Burne JF, King MP, Miyashita T, Reed JC, Raff MC (1993) Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA. Nature 361:365–369.
-
(1993)
Nature
, vol.361
, pp. 365-369
-
-
Jacobson, M.D.1
Burne, J.F.2
King, M.P.3
Miyashita, T.4
Reed, J.C.5
Raff, M.C.6
-
18
-
-
0019480519
-
Monitoring of relative mitochondrial membrane potential in living cells by fluoresence microscopy
-
Johnson LV, Walsh ML, Bockus BJ, Chen IB (1981) Monitoring of relative mitochondrial membrane potential in living cells by fluoresence microscopy. J Cell Biol 88:526–535.
-
(1981)
J Cell Biol
, vol.88
, pp. 526-535
-
-
Johnson, L.V.1
Walsh, M.L.2
Bockus, B.J.3
Chen, I.B.4
-
19
-
-
0028272055
-
(-)-deprenyl alters the time course of death of axotomized facial motoneurons and the hypertrophy of neighboring astrocytes in immature rats
-
Ju WY, Holland DP, Tatton WG (1994) (-)-Deprenyl alters the time course of death of axotomized facial motoneurons and the hypertrophy of neighboring astrocytes in immature rats. Exp Neurol 126:233–246.
-
(1994)
Exp Neurol
, vol.126
, pp. 233-246
-
-
Ju, W.Y.1
Holland, D.P.2
Tatton, W.G.3
-
20
-
-
0031587781
-
Release of cytochrome c from liver mitochondria during permeability transition
-
Kantrow SP, Piantadosi CA (1997) Release of cytochrome c from liver mitochondria during permeability transition. Biochem Biophys Res Commun 232:669–671.
-
(1997)
Biochem Biophys Res Commun
, vol.232
, pp. 669-671
-
-
Kantrow, S.P.1
Piantadosi, C.A.2
-
21
-
-
0029869269
-
Ngf, bdnf and nt-5, but not nt-3 protect against mpp(+) toxicity and oxidative stress in neonatal animals
-
Kirschner PB, Jenkins BG, Schulz JB, Finkelstein SP, Matthews RT, Rosen BR, Beal MF (1996) NGF, BDNF and NT-5, but not NT-3 protect against MPP(+) toxicity and oxidative stress in neonatal animals. Brain Res 713:178–185.
-
(1996)
Brain Res
, vol.713
, pp. 178-185
-
-
Kirschner, P.B.1
Jenkins, B.G.2
Schulz, J.B.3
Finkelstein, S.P.4
Matthews, R.T.5
Rosen, B.R.6
Beal, M.F.7
-
22
-
-
0028260335
-
Ivy go (1994) (-)-deprenyl increases the life span as well as activities of superoxide dismutase and catalase but not of glutathione peroxidase in selective brain regions in fischer rats
-
Kitani K, Kanai S, Carrillo MC, Ivy GO (1994) (-)-Deprenyl increases the life span as well as activities of superoxide dismutase and catalase but not of glutathione peroxidase in selective brain regions in Fischer rats. Ann NY Acad Sci 717:60–71.
-
Ann NY Acad Sci
, vol.717
, pp. 60-71
-
-
Kitani, K.1
Kanai, S.2
Carrillo, M.C.3
-
23
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for bcl-2 regulation
-
Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD (1997) The release of cytochrome C from mitochondria: a primary site for BCL-2 regulation. Science 275:1132–1136.
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
-
24
-
-
0030582079
-
Selegiline is neuroprotective in primary brain cultures treated with 1-methyl-4-phenylpyridinium
-
Koutsilieri E, Chen TS, Rausch WD, Riederer P (1996) Selegiline is neuroprotective in primary brain cultures treated with 1-methyl-4-phenylpyridinium. Eur J Pharmacol 306:181–186.
-
(1996)
Eur J Pharmacol
, vol.306
, pp. 181-186
-
-
Koutsilieri, E.1
Chen, T.S.2
Rausch, W.D.3
Riederer, P.4
-
25
-
-
0030047794
-
Opening of the mitochondrial permeability pore by uncoupling or inorganic phosphate in the presence of ca 2+ is dependent on mitochondrial-generated reactive oxygen species
-
2+ is dependent on mitochondrial-generated reactive oxygen species. FEBS Lett 378:150-152
-
(1996)
FEBS Lett
, vol.378
, pp. 150-152
-
-
Kowaltowski, A.J.1
Castilho, R.F.2
Vercesi, A.E.3
-
26
-
-
0029811838
-
Loss of function of cytochrome c in jurkat cells undergoing fas-mediated apoptosis
-
Krippner A, Matsuno-Yagi A, Gottlieb RA, Babior BM (1996) Loss of function of cytochrome c in Jurkat cells undergoing Fas-mediated apoptosis. J Biol Chem 271:21629–21636.
-
(1996)
J Biol Chem
, vol.271
, pp. 21629-21636
-
-
Krippner, A.1
Matsuno-Yagi, A.2
Gottlieb, R.A.3
Babior, B.M.4
-
27
-
-
0026554428
-
Evaluation of the probe 2',7'-dichlorofluorescein as an indicator of reactive oxygen species formation and oxidative stress
-
LeBel CP, Ischiropoulos H, Bondy SC (1992) Evaluation of the probe 2',7'-dichlorofluorescein as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 5:227–231.
-
(1992)
Chem Res Toxicol
, vol.5
, pp. 227-231
-
-
Lebel, C.P.1
Ischiropoulos, H.2
Bondy, S.C.3
-
28
-
-
0030023087
-
Detection of apoptosis and dna replication by differential labeling of dna strand breaks with fluorochromes of different color
-
Li X, Melamed MR, Darzynkiewicz Z (1996) Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color. Exp Cell Res 222:28–37.
-
(1996)
Exp Cell Res
, vol.222
, pp. 28-37
-
-
Li, X.1
Melamed, M.R.2
Darzynkiewicz, Z.3
-
29
-
-
0026564087
-
Specific irreversible monoamine oxidase-b inhibitors stimulate gene expression of aromatic l-amino acid decarboxylase in pc12 cells
-
Li XM, Juorio AV, Paterson IA, Zhu MY, Boulton AA (1992) Specific irreversible monoamine oxidase-B inhibitors stimulate gene expression of aromatic L-amino acid decarboxylase in PC12 cells. J Neurochem 59:2324–2327.
-
(1992)
J Neurochem
, vol.59
, pp. 2324-2327
-
-
Li, X.M.1
Juorio, A.V.2
Paterson, I.A.3
Zhu, M.Y.4
Boulton, A.A.5
-
30
-
-
0027358777
-
Reduction in glial fibrillary acidic protein messenger rna abundance induced by (-)-deprenyl and other monoamine oxidase b inhibitors in c6 glioma cells
-
Li XM, Qi J, Juorio AV, Boulton AA (1993) Reduction in glial fibrillary acidic protein messenger RNA abundance induced by (-)-deprenyl and other monoamine oxidase B inhibitors in C6 glioma cells. J Neurochem 61:1573–1576.
-
(1993)
J Neurochem
, vol.61
, pp. 1573-1576
-
-
Li, X.M.1
Qi, J.2
Juorio, A.V.3
Boulton, A.A.4
-
31
-
-
0027977928
-
The protein product of the oncogene bcl-2 is a component of the nuclear envelope, the endoplasmic reticulum, and the outer mitochondrial membrane
-
Lithgow T, van Driel R, Bertram JF, Strasser A (1994) The protein product of the oncogene bcl-2 is a component of the nuclear envelope, the endoplasmic reticulum, and the outer mitochondrial membrane. Cell Growth Differ 5:411–417.
-
(1994)
Cell Growth Differ
, vol.5
, pp. 411-417
-
-
Lithgow, T.1
Van Driel, R.2
Bertram, J.F.3
Strasser, A.4
-
32
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for datp and cytochrome c
-
Liu XS, Kim CN, Yang J, Jemmerson R, Wang XD (1996) Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86:147–157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.S.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.D.5
-
33
-
-
0029087118
-
Apoptosis in the nervous system: Morphological features, methods, pathology, and prevention
-
Lo AC, Houenou LJ, Oppenheim RW (1995) Apoptosis in the nervous system: morphological features, methods, pathology, and prevention. Arch Histol Cytol 58:139–149.
-
(1995)
Arch Histol Cytol
, vol.58
, pp. 139-149
-
-
Lo, A.C.1
Houenou, L.J.2
Oppenheim, R.W.3
-
34
-
-
0029966796
-
Chloromethyl-x-rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis
-
Macho A, Decaudin D, Castedo M, Hirsch T, Susin SA, Zamzami N, Kroemer G (1996) Chloromethyl-X-rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. Cytometry 25:333–340.
-
(1996)
Cytometry
, vol.25
, pp. 333-340
-
-
Macho, A.1
Decaudin, D.2
Castedo, M.3
Hirsch, T.4
Susin, S.A.5
Zamzami, N.6
Kroemer, G.7
-
35
-
-
9544246860
-
Mitochondrial permeability transition is a central coordinating event of apoptosis
-
Marchetti P, Castedo M, Susin SA, Zamzami N, Hirsch T, Macho A, Haeffner A, Hirsch F, Geuskens M, Kroemer G (1996a) Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med 184:1155–1160.
-
(1996)
J Exp Med
, vol.184
, pp. 1155-1160
-
-
Marchetti, P.1
Castedo, M.2
Susin, S.A.3
Zamzami, N.4
Hirsch, T.5
Macho, A.6
Haeffner, A.7
Hirsch, F.8
Geuskens, M.9
Kroemer, G.10
-
36
-
-
0030471143
-
Mitochondrial permeability transition triggers lymphocyte apoptosis
-
Marchetti P, Hirsch T, Zamzami N, Castedo M, Decaudin D, Susin SA, Masse B, Kroemer G (1996b) Mitochondrial permeability transition triggers lymphocyte apoptosis. J Immunol 157:4830–4836.
-
(1996)
J Immunol
, vol.157
, pp. 4830-4836
-
-
Marchetti, P.1
Hirsch, T.2
Zamzami, N.3
Castedo, M.4
Decaudin, D.5
Susin, S.A.6
Masse, B.7
Kroemer, G.8
-
37
-
-
9244237035
-
Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial dna
-
Marchetti P, Susin SA, Decaudin D, Gamen S, Castedo M, Hirsch T, Zamzami N, Naval J, Senik A, Kroemer G (1996c) Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA. Cancer Res 56:2033–2038.
-
(1996)
Cancer Res
, vol.56
, pp. 2033-2038
-
-
Marchetti, P.1
Susin, S.A.2
Decaudin, D.3
Gamen, S.4
Castedo, M.5
Hirsch, T.6
Zamzami, N.7
Naval, J.8
Senik, A.9
Kroemer, G.10
-
38
-
-
0028297573
-
The brain protein s-100ab induces apoptosis in pc12 cells
-
Mariggio MA, Fulle S, Calissano P, Nicoletti I, Fano G (1994) The brain protein S-100ab induces apoptosis in PC12 cells. Neuroscience 60:29–35.
-
(1994)
Neuroscience
, vol.60
, pp. 29-35
-
-
Mariggio, M.A.1
Fulle, S.2
Calissano, P.3
Nicoletti, I.4
Fano, G.5
-
39
-
-
0027319561
-
Growth factors prevent mitochondrial dysfunction, loss of ca 2+ homeostasis, and cell injury, but not atp depletion in hippocampal neurons deprived of glucose
-
2+ homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose. Exp Neurol 121:1–13.
-
(1993)
Exp Neurol
, vol.121
, pp. 1-13
-
-
Mattson, M.P.1
Zhang, Y.2
Bose, S.3
-
40
-
-
0026591024
-
Isolation of the mitochondrial benzodiazepine receptor: Association with the voltage dependent anion channel and the adenine nucleotide carrier
-
McEnery MW (1992) Isolation of the mitochondrial benzodiazepine receptor: association with the voltage dependent anion channel and the adenine nucleotide carrier. Proc Natl Acad Sci USA 89:3170–3174.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 3170-3174
-
-
McEnery, M.W.1
-
41
-
-
0027071804
-
Nerve growth factor withdrawal-induced cell death in neuronal pc12 cells resembles that in sympathetic neurons
-
Mesner PW, Winters TR, Green SH (1992) Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons. J Cell Biol 119:1669–1680.
-
(1992)
J Cell Biol
, vol.119
, pp. 1669-1680
-
-
Mesner, P.W.1
Winters, T.R.2
Green, S.H.3
-
42
-
-
0028839253
-
A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal pc12 cells
-
Mesner PW, Epting CL, Hegarty JL, Green SH (1995) A timetable of events during programmed cell death induced by trophic factor withdrawal from neuronal PC12 cells. J Neurosci 15:7357–7366.
-
(1995)
J Neurosci
, vol.15
, pp. 7357-7366
-
-
Mesner, P.W.1
Epting, C.L.2
Hegarty, J.L.3
Green, S.H.4
-
43
-
-
0024336003
-
Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores
-
Minta A, Kao J, Tsien R (1989) Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. J Biol Chem 264:8171–8185.
-
(1989)
J Biol Chem
, vol.264
, pp. 8171-8185
-
-
Minta, A.1
Kao, J.2
Tsien, R.3
-
44
-
-
0029845983
-
Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria
-
Murphy AN, Bredesen DE, Cortopassi G, Wang E, Fiskum G (1996) Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria. Proc Natl Acad Sci USA 93:9893–9898.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9893-9898
-
-
Murphy, A.N.1
Bredesen, D.E.2
Cortopassi, G.3
Wang, E.4
Fiskum, G.5
-
45
-
-
0028019746
-
Cell-free apoptosis in xenopus egg extracts: Inhibition by bcl-2 and requirement for an organelle fraction enriched in mitochondria
-
Newmeyer DD, Farschon DM, Reed JC (1994) Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell 79:353–364.
-
(1994)
Cell
, vol.79
, pp. 353-364
-
-
Newmeyer, D.D.1
Farschon, D.M.2
Reed, J.C.3
-
46
-
-
0028289951
-
Role of membrane anchor domain of bcl-2 in suppression of apoptosis caused by e1b-defective adenovirus
-
Nguyen M, Branton PE, Walton PA, Oltvai ZN, Korsmeyer SJ, Shore GC (1994) Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus. J Biol Chem 269:16521–16524.
-
(1994)
J Biol Chem
, vol.269
, pp. 16521-16524
-
-
Nguyen, M.1
Branton, P.E.2
Walton, P.A.3
Oltvai, Z.N.4
Korsmeyer, S.J.5
Shore, G.C.6
-
47
-
-
0029036412
-
Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis
-
Petit PX, Lecoeur H, Zorn E, Dauguet C, Mignotte B, Gougeon ML (1995) Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J Cell Biol 130:157–167.
-
(1995)
J Cell Biol
, vol.130
, pp. 157-167
-
-
Petit, P.X.1
Lecoeur, H.2
Zorn, E.3
Dauguet, C.4
Mignotte, B.5
Gougeon, M.L.6
-
48
-
-
0027325097
-
Pro-oxidants and mitochondrial ca 2+: Their relationship to apoptosis and oncogenesis
-
2+: their relationship to apoptosis and oncogenesis. FEBS Lett 325:104–107.
-
(1993)
FEBS Lett
, vol.325
, pp. 104-107
-
-
Richter, C.1
-
49
-
-
0029071509
-
Oxidants in mitochondria: From physiology to diseases
-
Richter C, Gogvadze V, Laffranchi R, Schlapbach R, Schweizer M, Suter M, Walter P, Yaffee M (1995) Oxidants in mitochondria: from physiology to diseases. Biochim Biophys Acta 1271:67–74.
-
(1995)
Biochim Biophys Acta
, vol.1271
, pp. 67-74
-
-
Richter, C.1
Gogvadze, V.2
Laffranchi, R.3
Schlapbach, R.4
Schweizer, M.5
Suter, M.6
Walter, P.7
Yaffee, M.8
-
50
-
-
0025939423
-
Multiple agents rescue pc12 cells from serum-free cell death by translation- and transcription-independent mechanisms
-
Rukenstein A, Rydel RE, Greene LA (1991) Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms. J Neurosci 11:2552–2563.
-
(1991)
J Neurosci
, vol.11
, pp. 2552-2563
-
-
Rukenstein, A.1
Rydel, R.E.2
Greene, L.A.3
-
51
-
-
0023473236
-
Acidic and basic fibroblast growth factors promote stable neurite outgrowth and neuronal differentiation in cultures of pc12 cells
-
Rydel RE, Greene LA (1987) Acidic and basic fibroblast growth factors promote stable neurite outgrowth and neuronal differentiation in cultures of PC12 cells. J Neurosci 7:3639–3653.
-
(1987)
J Neurosci
, vol.7
, pp. 3639-3653
-
-
Rydel, R.E.1
Greene, L.A.2
-
52
-
-
0030574241
-
Selegiline enhances ngf synthesis and protects central nervous system neurons from excitotoxic and ischemic damage
-
Semkova I, Wolz P, Schilling M, Krieglstein J (1996) Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage. Eur J Pharmacol 315:19–30.
-
(1996)
Eur J Pharmacol
, vol.315
, pp. 19-30
-
-
Semkova, I.1
Wolz, P.2
Schilling, M.3
Krieglstein, J.4
-
53
-
-
0028121120
-
Increased cntf gene expression in process-bearing astrocytes following injury is augmented by r(-)-deprenyl
-
Seniuk NA, Henderson JT, Tatton WG, Roder JC (1994) Increased CNTF gene expression in process-bearing astrocytes following injury is augmented by R(-)-deprenyl. J Neurosci Res 37:278–286.
-
(1994)
J Neurosci Res
, vol.37
, pp. 278-286
-
-
Seniuk, N.A.1
Henderson, J.T.2
Tatton, W.G.3
Roder, J.C.4
-
54
-
-
0025864201
-
Mitochondria: Structure and function
-
Sherratt HSA (1991) Mitochondria: structure and function. Rev Neurol (Paris) 147:417–430.
-
(1991)
Rev Neurol (Paris)
, vol.147
, pp. 417-430
-
-
Sherratt, H.S.A.1
-
56
-
-
0026802181
-
A fluorescence-microscopic and flow-cytometric study of hela cells with an experimentally induced respiratory deficiency
-
Skowronek P, Haferkamp O, Rodel G (1992) A fluorescence-microscopic and flow-cytometric study of HeLa cells with an experimentally induced respiratory deficiency. Biochem Biophys Res Commun 187:991–998.
-
(1992)
Biochem Biophys Res Commun
, vol.187
, pp. 991-998
-
-
Skowronek, P.1
Haferkamp, O.2
Rodel, G.3
-
57
-
-
0030580287
-
Why are mitochondria involved in apoptosis? Permeability transition pores and apoptosis as selective mechanisms to eliminate superoxide-producing mitochondria and cell
-
Skulachev VP (1996) Why are mitochondria involved in apoptosis? Permeability transition pores and apoptosis as selective mechanisms to eliminate superoxide-producing mitochondria and cell. FEBS Lett 397:7–10.
-
(1996)
FEBS Lett
, vol.397
, pp. 7-10
-
-
Skulachev, V.P.1
-
58
-
-
0025806764
-
Intracellular heterogeneity in mitochondrial membrane potentials revealed by j-aggregate-forming lipophilic cation jc-1
-
Smiley ST, Reers M, Mottola-Hartshorn C, Lin M, Chen A, Smith T, Steele GD, Chen L (1991) Intracellular heterogeneity in mitochondrial membrane potentials revealed by J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci USA 88:3671–3675.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 3671-3675
-
-
Smiley, S.T.1
Reers, M.2
Mottola-Hartshorn, C.3
Lin, M.4
Chen, A.5
Smith, T.6
Steele, G.D.7
Chen, L.8
-
59
-
-
0022263028
-
The role of estrogens on the proliferation of human breast tumor cells (mcf-7)
-
Soto AM, Sonnenschein C (1985) The role of estrogens on the proliferation of human breast tumor cells (MCF-7). J Steroid Biochem 23:87–94.
-
(1985)
J Steroid Biochem
, vol.23
, pp. 87-94
-
-
Soto, A.M.1
Sonnenschein, C.2
-
60
-
-
0029950290
-
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
-
Susin SA, Zamzami N, Castedo M, Hirsch T, Marchetti P, Macho A, Daugas E, Geuskens M, Kroemer G (1996a) Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 184:1331–1341.
-
(1996)
J Exp Med
, vol.184
, pp. 1331-1341
-
-
Susin, S.A.1
Zamzami, N.2
Castedo, M.3
Hirsch, T.4
Marchetti, P.5
Macho, A.6
Daugas, E.7
Geuskens, M.8
Kroemer, G.9
-
61
-
-
0001425438
-
The cell biology of apoptosis: Evidence for the implication of mitochondria
-
Susin SA, Zamzami N, Kroemer G (1996b) The cell biology of apoptosis: evidence for the implication of mitochondria. Apoptosis 1:231–242.
-
(1996)
Apoptosis
, vol.1
, pp. 231-242
-
-
Susin, S.A.1
Zamzami, N.2
Kroemer, G.3
-
62
-
-
0027225445
-
Structure-function analysis of the bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the bcl-2 beta protein restores function as a regulator of cell survival
-
Tanaka S, Saito K, Reed JC (1993) Structure-function analysis of the Bcl-2 oncoprotein. Addition of a heterologous transmembrane domain to portions of the Bcl-2 beta protein restores function as a regulator of cell survival. J Biol Chem 268:10920–10926.
-
(1993)
J Biol Chem
, vol.268
, pp. 10920-10926
-
-
Tanaka, S.1
Saito, K.2
Reed, J.C.3
-
63
-
-
0029731378
-
Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration
-
Tatton WG, Chalmers-Redman RME (1996) Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration. Neurology 47:S171–S183.
-
(1996)
Neurology
, vol.47
, pp. S171-S183
-
-
Tatton, W.G.1
Chalmers-Redman, R.M.E.2
-
64
-
-
0007298326
-
(-)-deprenyl reduces neuronal apoptosis by maintaining bcl-2 synthesis and mitochondrial membrane potential
-
Tatton WG, Ju W, Wadia J, Ansari K, Zhang F, Buys Y, Seniuk N (1994a) (-)-Deprenyl reduces neuronal apoptosis by maintaining Bcl-2 synthesis and mitochondrial membrane potential. Mov Disord 9:4.
-
(1994)
Mov Disord
, vol.9
, Issue.4
-
-
Tatton, W.G.1
Ju, W.2
Wadia, J.3
Ansari, K.4
Zhang, F.5
Buys, Y.6
Seniuk, N.7
-
65
-
-
0027941312
-
Kwan m (1994b) (-)-deprenyl reduces pc12 cell apoptosis by inducing new protein synthesis
-
Tatton WG, Ju WY, Holland DP, Tai C, Kwan M (1994b) (-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis. J Neurochem 63:1572–1575.
-
J Neurochem
, vol.63
, pp. 1572-1575
-
-
Tatton, W.G.1
Ju, W.Y.2
Holland, D.P.3
Tai, C.4
-
66
-
-
0000191245
-
Reduction of neuronal apoptosis by small molecules: Promise for new approaches to neurological therapy
-
Olanow CW, Jenner P, Youdim M, eds, London: Academic
-
Tatton WG, Ju WJH, Wadia J, Tatton NA (1996) Reduction of neuronal apoptosis by small molecules: promise for new approaches to neurological therapy. In: Neurodegeneration and neuroprotection in parkin-son’s disease (Olanow CW, Jenner P, Youdim M, eds), pp 209–229. London: Academic.
-
(1996)
Neurodegeneration and Neuroprotection in Parkin-Son’S Disease
, pp. 209-229
-
-
Tatton, W.G.1
Ju, W.J.H.2
Wadia, J.3
Tatton, N.A.4
-
67
-
-
0028971624
-
Effect of mptp and l-deprenyl on antioxidant enzymes and lipid peroxidation levels in mouse brain
-
Thiffault C, Aumont N, Quirion R, Poirier J (1995) Effect of MPTP and L-deprenyl on antioxidant enzymes and lipid peroxidation levels in mouse brain. J Neurochem 65:2725–2733.
-
(1995)
J Neurochem
, vol.65
, pp. 2725-2733
-
-
Thiffault, C.1
Aumont, N.2
Quirion, R.3
Poirier, J.4
-
68
-
-
0030581492
-
A critical evaluation of in situ measurement of mitochondrial potentials in single hepatocytes
-
Ubl JJ, Chatton J-Y, S C, Stucki JW (1996) A critical evaluation of in situ measurement of mitochondrial potentials in single hepatocytes. Biochim Biophys Acta 1276:124–132.
-
(1996)
Biochim Biophys Acta
, vol.1276
, pp. 124-132
-
-
Ubl, J.J.1
Chatton, J.-Y.2
Stucki, J.W.3
-
69
-
-
0027436057
-
The participation of reactive oxygen species and protein thiols in the mechanism of mitochondrial inner membrane permeabilization by calcium plus prooxidants
-
Valle VGR, Fagian MM, Parentoni LS, Meinicke AR, Vercesi AE (1993) The participation of reactive oxygen species and protein thiols in the mechanism of mitochondrial inner membrane permeabilization by calcium plus prooxidants. Arch Biochem Biophys 307:1–7.
-
(1993)
Arch Biochem Biophys
, vol.307
, pp. 1-7
-
-
Valle, V.G.R.1
Fagian, M.M.2
Parentoni, L.S.3
Meinicke, A.R.4
Vercesi, A.E.5
-
70
-
-
0028046038
-
Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40
-
Vayssiere JL, Petit PX, Risler Y, Mignotte B (1994) Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc Natl Acad Sci USA 91:11752–11756.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11752-11756
-
-
Vayssiere, J.L.1
Petit, P.X.2
Risler, Y.3
Mignotte, B.4
-
71
-
-
0028267301
-
Mitochondrial respiratory chain inhibitors induce apoptosis
-
Wolvetang EJ, Johnson KL, Krauer K, Ralph SJ, Linnane AW (1994) Mitochondrial respiratory chain inhibitors induce apoptosis. FEBS Lett 339:40–44.
-
(1994)
FEBS Lett
, vol.339
, pp. 40-44
-
-
Wolvetang, E.J.1
Johnson, K.L.2
Krauer, K.3
Ralph, S.J.4
Linnane, A.W.5
-
72
-
-
0027517052
-
Apparent antioxidant effect of l-deprenyl on hydroxyl radical formation and nigral injury elicited by mpp+ in vivo
-
Wu RM, Chiueh CC, Pert A, Murphy DL (1993) Apparent antioxidant effect of L-deprenyl on hydroxyl radical formation and nigral injury elicited by MPP+ in vivo. Eur J Pharmacol 243:241–247.
-
(1993)
Eur J Pharmacol
, vol.243
, pp. 241-247
-
-
Wu, R.M.1
Chiueh, C.C.2
Pert, A.3
Murphy, D.L.4
-
73
-
-
0031036872
-
Prevention of apoptosis by bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang J, Liu XS, Bhalla K, Kim CN, Ibrado AM, Cai JY, Peng TI, Jones DP, Wang XD (1997) Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Science 275:1129–1132.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.S.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.Y.6
Peng, T.I.7
Jones, D.P.8
Wang, X.D.9
-
74
-
-
0023029305
-
Contrasting monoamine oxidase activity and tyramine induced cate-cholamine release in pc12 and chromaffin cells
-
Youdim MB, Heldman E, Pollard HB, Fleming P, McHugh ESO (1986) Contrasting monoamine oxidase activity and tyramine induced cate-cholamine release in PC12 and chromaffin cells. Neuroscience 19:1311–1318.
-
(1986)
Neuroscience
, vol.19
, pp. 1311-1318
-
-
Youdim, M.B.1
Heldman, E.2
Pollard, H.B.3
Fleming, P.4
McHugh, E.S.O.5
-
75
-
-
0028903933
-
Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo
-
Zamzami N, Marchetti P, Castedo M, Zanin C, Vayssiere JL, Petit PX, Kroemer G (1995a) Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J Exp Med 181:1661–1672.
-
(1995)
J Exp Med
, vol.181
, pp. 1661-1672
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
Zanin, C.4
Vayssiere, J.L.5
Petit, P.X.6
Kroemer, G.7
-
76
-
-
0029983059
-
Inhibitors of permeability transition interfere with the disruption of mitochondrial transmembrane potential during apoptosis
-
Zamzami N, Marchetti P, Castedo M, Hirsh T, Susin SA, Masse B, Kroemer G (1996a) Inhibitors of permeability transition interfere with the disruption of mitochondrial transmembrane potential during apoptosis. FEBS Lett 384:53–57.
-
(1996)
FEBS Lett
, vol.384
, pp. 53-57
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
Hirsh, T.4
Susin, S.A.5
Masse, B.6
Kroemer, G.7
-
77
-
-
0029862706
-
Mitochondrial control of nuclear apoptosis
-
Zamzami N, Susin SA, Marchetti P, Hirsch T, Gomez-Monterrey I, Castedo M, Kroemer G (1996b) Mitochondrial control of nuclear apoptosis. J Exp Med 183:1533–1544.
-
(1996)
J Exp Med
, vol.183
, pp. 1533-1544
-
-
Zamzami, N.1
Susin, S.A.2
Marchetti, P.3
Hirsch, T.4
Gomez-Monterrey, I.5
Castedo, M.6
Kroemer, G.7
-
78
-
-
0029938017
-
Immuno-histochemical evidence of neuroprotection by r(-)-deprenyl and n-(2-hexyl)-n-methylpropargylamine on dsp-4-induced degeneration of rat brain noradrenergic axons and terminals
-
Zhang X, Zuo DM, Davis BA, Boulton AA, Yu PH (1996) Immuno-histochemical evidence of neuroprotection by R(-)-deprenyl and N-(2-hexyl)-N-methylpropargylamine on DSP-4-induced degeneration of rat brain noradrenergic axons and terminals. J Neurosci Res 43:482–489.
-
(1996)
J Neurosci Res
, vol.43
, pp. 482-489
-
-
Zhang, X.1
Zuo, D.M.2
Davis, B.A.3
Boulton, A.A.4
Yu, P.H.5
-
79
-
-
0029116916
-
The mitochondrial permeability transition
-
Zoratti M, Szabo I (1995) The mitochondrial permeability transition. Biochim Biophys Acta 1241:139–176.
-
(1995)
Biochim Biophys Acta
, vol.1241
, pp. 139-176
-
-
Zoratti, M.1
Szabo, I.2
|