-
1
-
-
0028124428
-
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
-
Rothe M., Wong S. C., Henzel W. J., Goeddel D. V. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell. 78:1994;681-692.
-
(1994)
Cell
, vol.78
, pp. 681-692
-
-
Rothe, M.1
Wong, S.C.2
Henzel, W.J.3
Goeddel, D.V.4
-
2
-
-
0027943499
-
A novel RING finger protein interacts with the cytoplasmic domain of CD40
-
Hu H. M., O'Rourke K., Boguski M. S., Dixit V. M. A novel RING finger protein interacts with the cytoplasmic domain of CD40. J. Biol. Chem. 269:1994;30069-30072.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30069-30072
-
-
Hu, H.M.1
O'Rourke, K.2
Boguski, M.S.3
Dixit, V.M.4
-
3
-
-
0028936733
-
Involvement of CRAF1, a relative of TRAF, in CD40 signaling
-
Cheng G., Cleary A. M., Ye Z. S., Hong D. I., Lederman S., Baltimore D. Involvement of CRAF1, a relative of TRAF, in CD40 signaling. Science. 267:1995;1494-1498.
-
(1995)
Science
, vol.267
, pp. 1494-1498
-
-
Cheng, G.1
Cleary, A.M.2
Ye, Z.S.3
Hong, D.I.4
Lederman, S.5
Baltimore, D.6
-
4
-
-
0028878977
-
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family
-
Mosialos G., Birkenbach M., Yalamanchili R., VanArsdale T., Ware C., Kieff E. The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. Cell. 80:1995;389-399.
-
(1995)
Cell
, vol.80
, pp. 389-399
-
-
Mosialos, G.1
Birkenbach, M.2
Yalamanchili, R.3
Vanarsdale, T.4
Ware, C.5
Kieff, E.6
-
5
-
-
0028809176
-
A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40
-
Sato T., Irie S., Reed J. C. A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40. FEBS Lett. 358:1995;113-118.
-
(1995)
FEBS Lett.
, vol.358
, pp. 113-118
-
-
Sato, T.1
Irie, S.2
Reed, J.C.3
-
6
-
-
0028856787
-
Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma
-
Regnier C. H., Tomasetto C., Moog-Lutz C., Chenard M. P., Wendling C., Basset P., Rio M. C. Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma. J. Biol. Chem. 270:1995;25715-25721.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25715-25721
-
-
Regnier, C.H.1
Tomasetto, C.2
Moog-Lutz, C.3
Chenard, M.P.4
Wendling, C.5
Basset, P.6
Rio, M.C.7
-
7
-
-
15844428836
-
TRAF5, an activator of NF-κB and putative signal transducer for the lymphotoxin-β receptor
-
Nakano H., Oshima H., Chung W., Williams-Abbott L., Ware C. F., Yagita H., Okumura K. TRAF5, an activator of NF-κB and putative signal transducer for the lymphotoxin-β receptor. J. Biol. Chem. 271:1996;14661-14664.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14661-14664
-
-
Nakano, H.1
Oshima, H.2
Chung, W.3
Williams-Abbott, L.4
Ware, C.F.5
Yagita, H.6
Okumura, K.7
-
8
-
-
0029847814
-
TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling
-
Ishida T. K., Tojo T., Aoki T., Kobayashi N., Ohishi T., Watanabe T., Yamamoto T., Inoue J. TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling. Proc. Natl. Acad. Sci. USA. 93:1996;9437-9442.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9437-9442
-
-
Ishida, T.K.1
Tojo, T.2
Aoki, T.3
Kobayashi, N.4
Ohishi, T.5
Watanabe, T.6
Yamamoto, T.7
Inoue, J.8
-
9
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao Z., Xiong J., Takeuchi M., Kurama T., Goeddel D. V. TRAF6 is a signal transducer for interleukin-1. Nature. 383:1996;443-446.
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
10
-
-
10544243364
-
Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region
-
Ishida T., Mizushima S., Azuma S., Kobayashi N., Tojo T., Suzuki K., Aizawa S., Watanabe T., Mosialos G., Kieff E., Yamamoto T., Inoue J. Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region. J. Biol. Chem. 271:1996;28745-28748.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 28745-28748
-
-
Ishida, T.1
Mizushima, S.2
Azuma, S.3
Kobayashi, N.4
Tojo, T.5
Suzuki, K.6
Aizawa, S.7
Watanabe, T.8
Mosialos, G.9
Kieff, E.10
Yamamoto, T.11
Inoue, J.12
-
11
-
-
0344178160
-
Identification of a TRAF (TNF receptor-associated factor) gene in Caenorhabditis elegans
-
Wajant H., Muhlenbeck F., Scheurich P. Identification of a TRAF (TNF receptor-associated factor) gene in Caenorhabditis elegans. J. Mol. Evol. 47:1998;656-662.
-
(1998)
J. Mol. Evol.
, vol.47
, pp. 656-662
-
-
Wajant, H.1
Muhlenbeck, F.2
Scheurich, P.3
-
12
-
-
0033611551
-
A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase
-
Liu H., Su Y. C., Becker E., Treisman J., Skolnik E. Y. A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase. Curr. Biol. 9:1999;101-104.
-
(1999)
Curr. Biol.
, vol.9
, pp. 101-104
-
-
Liu, H.1
Su, Y.C.2
Becker, E.3
Treisman, J.4
Skolnik, E.Y.5
-
13
-
-
1842366717
-
A regulatory role for TRAF1 in antigen-induced apoptosis of T cells
-
Speiser D. E., Lee S. Y., Wong B., Arron J., Santana A., Kong Y. Y., Ohashi P. S., Choi Y. A regulatory role for TRAF1 in antigen-induced apoptosis of T cells. J. Exp. Med. 185:1997;1777-1783.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1777-1783
-
-
Speiser, D.E.1
Lee, S.Y.2
Wong, B.3
Arron, J.4
Santana, A.5
Kong, Y.Y.6
Ohashi, P.S.7
Choi, Y.8
-
14
-
-
0030292777
-
Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses
-
Xu Y., Cheng G., Baltimore D. Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. Immunity. 5:1996;407-415.
-
(1996)
Immunity
, vol.5
, pp. 407-415
-
-
Xu, Y.1
Cheng, G.2
Baltimore, D.3
-
15
-
-
0029007855
-
The TNF receptor 1-associated protein TRADD signals cell death and NF-κ B activation
-
Hsu H., Xiong J., Goeddel D. V. The TNF receptor 1-associated protein TRADD signals cell death and NF-κ B activation. Cell. 81:1995;495-504.
-
(1995)
Cell
, vol.81
, pp. 495-504
-
-
Hsu, H.1
Xiong, J.2
Goeddel, D.V.3
-
16
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov R., Preston-Hurlburt P., Kopp E., Stadlen A., Chen C., Ghosh S., Janeway C. A. Jr. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol. Cell. 2:1998;253-258.
-
(1998)
Mol. Cell
, vol.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
Stadlen, A.4
Chen, C.5
Ghosh, S.6
Janeway C.A., Jr.7
-
17
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche H., Henzel W. J., Shillinglaw W., Li S., Cao Z. MyD88: An adapter that recruits IRAK to the IL-1 receptor complex. Immunity. 7:1997;837-847.
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
18
-
-
0027461317
-
Regulation of lymphocyte function by protein phosphorylation
-
Perlmutter R. M., Levin S. D., Appleby M. W., Anderson S. J., Alberola-Ila J. Regulation of lymphocyte function by protein phosphorylation. Annu. Rev. Immunol. 11:1993;451-499.
-
(1993)
Annu. Rev. Immunol.
, vol.11
, pp. 451-499
-
-
Perlmutter, R.M.1
Levin, S.D.2
Appleby, M.W.3
Anderson, S.J.4
Alberola-Ila, J.5
-
19
-
-
0024406857
-
A novel genetic system to detect protein-protein interactions
-
Fields S., Song O. A novel genetic system to detect protein-protein interactions. Nature. 340:1989;245-246.
-
(1989)
Nature
, vol.340
, pp. 245-246
-
-
Fields, S.1
Song, O.2
-
20
-
-
0029786304
-
Anatomy of TRAF2: Distinct domains for nuclear factor-κB activation and association with tumor necrosis factor signaling proteins
-
Takeuchi M., Rothe M., Goeddel D. V. Anatomy of TRAF2: Distinct domains for nuclear factor-κB activation and association with tumor necrosis factor signaling proteins. J. Biol. Chem. 271:1996;19935-19942.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19935-19942
-
-
Takeuchi, M.1
Rothe, M.2
Goeddel, D.V.3
-
21
-
-
0001033803
-
Structural basis for self-association and receptor recognition of human TRAF2
-
Park Y. C., Burkitt V., Villa A. R., Tong L., Wu H. Structural basis for self-association and receptor recognition of human TRAF2. Nature. 398:1999;533-538.
-
(1999)
Nature
, vol.398
, pp. 533-538
-
-
Park, Y.C.1
Burkitt, V.2
Villa, A.R.3
Tong, L.4
Wu, H.5
-
22
-
-
0033587691
-
Crystallographic analysis of CD40 recognition and signaling by human TRAF2
-
McWhirter S. M., Pullen S. S., Holton J. M., Crute J. J., Kehry M. R., Alber T. Crystallographic analysis of CD40 recognition and signaling by human TRAF2. Proc. Natl. Acad. Sci. USA. 96:1999;8408-8413.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 8408-8413
-
-
McWhirter, S.M.1
Pullen, S.S.2
Holton, J.M.3
Crute, J.J.4
Kehry, M.R.5
Alber, T.6
-
23
-
-
0040084598
-
CD30/TNF receptor-associated factor interaction: NF-κB activation and binding specificity
-
Lee S. Y., Lee S. Y., Kandala G., Liou M. L., Liou H. C., Choi Y. CD30/TNF receptor-associated factor interaction: NF-κB activation and binding specificity. Proc. Natl. Acad. Sci. USA. 93:1996;9699-9703.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 9699-9703
-
-
Lee, S.Y.1
Lee, S.Y.2
Kandala, G.3
Liou, M.L.4
Liou, H.C.5
Choi, Y.6
-
24
-
-
0030661665
-
Dominant negative mutants of TRAF3 reveal an important role for the coiled coil domains in cell death signaling by the lymphotoxin-β receptor
-
Force W. R., Cheung T. C., Ware C. F. Dominant negative mutants of TRAF3 reveal an important role for the coiled coil domains in cell death signaling by the lymphotoxin-β receptor. J. Biol. Chem. 272:1997;30835-30840.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30835-30840
-
-
Force, W.R.1
Cheung, T.C.2
Ware, C.F.3
-
25
-
-
0032493737
-
Characterization of the intracellular domain of receptor activator of NF-κB (RANK): Interaction with tumor necrosis factor receptor-associated factors and activation of NF-κB and c-Jun N-terminal kinase
-
Darnay B. G., Haridas V., Ni J., Moore P. A., Aggarwal B. B. Characterization of the intracellular domain of receptor activator of NF-κB (RANK): Interaction with tumor necrosis factor receptor-associated factors and activation of NF-κB and c-Jun N-terminal kinase. J. Biol. Chem. 273:1998;20551-20555.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 20551-20555
-
-
Darnay, B.G.1
Haridas, V.2
Ni, J.3
Moore, P.A.4
Aggarwal, B.B.5
-
26
-
-
0029956392
-
Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: Role in NF-κB activation
-
Devergne O., Hatzivassiliou E., Izumi K. M., Kaye K. M., Kleijnen M. F., Kieff E., Mosialos G. Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: Role in NF-κB activation. Mol. Cell. Biol. 16:1996;7098-7108.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 7098-7108
-
-
Devergne, O.1
Hatzivassiliou, E.2
Izumi, K.M.3
Kaye, K.M.4
Kleijnen, M.F.5
Kieff, E.6
Mosialos, G.7
-
27
-
-
15844369897
-
CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins
-
Gedrich R. W., Gilfillan M. C., Duckett C. S., Van Dongen J. L., Thompson C. B. CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins. J. Biol. Chem. 271:1996;12852-12858.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12852-12858
-
-
Gedrich, R.W.1
Gilfillan, M.C.2
Duckett, C.S.3
Van Dongen, J.L.4
Thompson, C.B.5
-
28
-
-
0033574060
-
Specificities of CD40 signaling: Involvement of TRAF2 in CD40-induced NF-κB activation and intercellular adhesion molecule-1 up-regulation
-
Lee H. H., Dempsey P. W., Parks T. P., Zhu X., Baltimore D., Cheng G. Specificities of CD40 signaling: involvement of TRAF2 in CD40-induced NF-κB activation and intercellular adhesion molecule-1 up-regulation. Proc. Natl. Acad. Sci. USA. 96:1999;1421-1426.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1421-1426
-
-
Lee, H.H.1
Dempsey, P.W.2
Parks, T.P.3
Zhu, X.4
Baltimore, D.5
Cheng, G.6
-
29
-
-
0033574051
-
Two differently regulated nuclear factor κb activation pathways triggered by the cytoplasmic tail of CD40
-
Tsukamoto N., Kobayashi N., Azuma S., Yamamoto T., Inoue J. Two differently regulated nuclear factor κB activation pathways triggered by the cytoplasmic tail of CD40. Proc. Natl. Acad. Sci. USA. 96:1999;1234-1239.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1234-1239
-
-
Tsukamoto, N.1
Kobayashi, N.2
Azuma, S.3
Yamamoto, T.4
Inoue, J.5
-
30
-
-
0032561198
-
The TRAF family of signal transducers mediates NF-κB activation by the TRANCE receptor
-
Wong B. R., Josien R., Lee S. Y., Vologodskaia M., Steinman R. M., Choi Y. The TRAF family of signal transducers mediates NF-κB activation by the TRANCE receptor. J. Biol. Chem. 273:1998;28355-28359.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28355-28359
-
-
Wong, B.R.1
Josien, R.2
Lee, S.Y.3
Vologodskaia, M.4
Steinman, R.M.5
Choi, Y.6
-
31
-
-
0032545465
-
The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-κB, a member of the TNFR superfamily
-
Galibert L., Tometsko M. E., Anderson D. M., Cosman D., Dougall W. C. The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-κB, a member of the TNFR superfamily. J. Biol. Chem. 273:1998;34120-34127.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34120-34127
-
-
Galibert, L.1
Tometsko, M.E.2
Anderson, D.M.3
Cosman, D.4
Dougall, W.C.5
-
32
-
-
0033582819
-
Activation of NF-κB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-κB-inducing kinase: Identification of a novel TRAF6 interaction motif
-
Darnay B. G., Ni J., Moore P. A., Aggarwal B. B. Activation of NF-κB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-κB-inducing kinase: Identification of a novel TRAF6 interaction motif. J. Biol. Chem. 274:1999;7724-7731.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7724-7731
-
-
Darnay, B.G.1
Ni, J.2
Moore, P.A.3
Aggarwal, B.B.4
-
33
-
-
0033613831
-
Association of the p75 neurotrophin receptor with TRAF6
-
Khursigara G., Orlinick J. R., Chao M. V. Association of the p75 neurotrophin receptor with TRAF6. J. Biol. Chem. 274:1999;2597-2600.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2597-2600
-
-
Khursigara, G.1
Orlinick, J.R.2
Chao, M.V.3
-
34
-
-
0031905311
-
A family of human receptors structurally related to Drosophila Toll
-
Rock F. L., Hardiman G., Timans J. C., Kastelein R. A., Bazan J. F. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. USA. 95:1998;588-593.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 588-593
-
-
Rock, F.L.1
Hardiman, G.2
Timans, J.C.3
Kastelein, R.A.4
Bazan, J.F.5
-
35
-
-
0032127279
-
Targeted disruption of the MyD88 gene results in loss of IL-1- And IL-18-mediated function
-
Adachi O., Kawai T., Takeda K., Matsumoto M., Tsutsui H., Sakagami M., Nakanishi K., Akira S. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity. 9:1998;143-150.
-
(1998)
Immunity
, vol.9
, pp. 143-150
-
-
Adachi, O.1
Kawai, T.2
Takeda, K.3
Matsumoto, M.4
Tsutsui, H.5
Sakagami, M.6
Nakanishi, K.7
Akira, S.8
-
36
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T., Adachi O., Ogawa T., Takeda K., Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity. 11:1999;115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
37
-
-
0032526861
-
The human toll signaling pathway: Divergence of nuclear factor κb and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)
-
Muzio M., Natoli G., Saccani S., Levrero M., Mantovani A. The human toll signaling pathway: Divergence of nuclear factor κB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6). J. Exp. Med. 187:1998;2097-2101.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 2097-2101
-
-
Muzio, M.1
Natoli, G.2
Saccani, S.3
Levrero, M.4
Mantovani, A.5
-
38
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
-
Muzio M., Ni J., Feng P., Dixit V. M. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science. 278:1997;1612-1615.
-
(1997)
Science
, vol.278
, pp. 1612-1615
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
39
-
-
0030851538
-
Assembly and regulation of the CD40 receptor complex in human B cells
-
Kuhne M. R., Robbins M., Hambor J. E., Mackey M. F., Kosaka Y., Nishimura T., Gigley J. P., Noelle R. J., Calderhead D. M. Assembly and regulation of the CD40 receptor complex in human B cells. J. Exp. Med. 186:1997;337-342.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 337-342
-
-
Kuhne, M.R.1
Robbins, M.2
Hambor, J.E.3
Mackey, M.F.4
Kosaka, Y.5
Nishimura, T.6
Gigley, J.P.7
Noelle, R.J.8
Calderhead, D.M.9
-
40
-
-
0030911873
-
Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κb
-
VanArsdale T. L., VanArsdale S. L., Force W. R., Walter B. N., Mosialos G., Kieff E., Reed J. C., Ware C. F. Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB. Proc. Natl. Acad. Sci. USA. 94:1997;2460-2465.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2460-2465
-
-
Vanarsdale, T.L.1
Vanarsdale, S.L.2
Force, W.R.3
Walter, B.N.4
Mosialos, G.5
Kieff, E.6
Reed, J.C.7
Ware, C.F.8
-
41
-
-
0032101119
-
CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand
-
Saoulli K., Lee S. Y., Cannons J. L., Yeh W. C., Santana A., Goldstein M. D., Bangia N., DeBenedette M. A., Mak T. W., Choi Y., Watts T. H. CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand. J. Exp. Med. 187:1998;1849-1862.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1849-1862
-
-
Saoulli, K.1
Lee, S.Y.2
Cannons, J.L.3
Yeh, W.C.4
Santana, A.5
Goldstein, M.D.6
Bangia, N.7
Debenedette, M.A.8
Mak, T.W.9
Choi, Y.10
Watts, T.H.11
-
42
-
-
0023192180
-
The active form of tumor necrosis factor is a trimer
-
Smith R. A., Baglioni C. The active form of tumor necrosis factor is a trimer. J. Biol. Chem. 262:1987;6951-6954.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 6951-6954
-
-
Smith, R.A.1
Baglioni, C.2
-
43
-
-
0030055168
-
Human pro-tumor necrosis factor is a homotrimer
-
Tang P., Hung M. C., Klostergaard J. Human pro-tumor necrosis factor is a homotrimer. Biochemistry. 35:1996;8216-8225.
-
(1996)
Biochemistry
, vol.35
, pp. 8216-8225
-
-
Tang, P.1
Hung, M.C.2
Klostergaard, J.3
-
44
-
-
0033563101
-
Signaling by proinflammatory cytokines: Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain
-
Baud V., Liu Z. G., Bennett B., Suzuki N., Xia Y., Karin M. Signaling by proinflammatory cytokines: Oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. Genes Dev. 13:1999;1297-1308.
-
(1999)
Genes Dev.
, vol.13
, pp. 1297-1308
-
-
Baud, V.1
Liu, Z.G.2
Bennett, B.3
Suzuki, N.4
Xia, Y.5
Karin, M.6
-
45
-
-
0028670788
-
Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
-
Yan M., Dai T., Deak J. C., Kyriakis J. M., Zon L. I., Woodgett J. R., Templeton D. J. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Nature. 372:1994;798-800.
-
(1994)
Nature
, vol.372
, pp. 798-800
-
-
Yan, M.1
Dai, T.2
Deak, J.C.3
Kyriakis, J.M.4
Zon, L.I.5
Woodgett, J.R.6
Templeton, D.J.7
-
46
-
-
0028558986
-
Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
-
Sanchez I., Hughes R. T., Mayer B. J., Yee K., Woodgett J. R., Avruch J., Kyriakis J. M., Zon L. I. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature. 372:1994;794-798.
-
(1994)
Nature
, vol.372
, pp. 794-798
-
-
Sanchez, I.1
Hughes, R.T.2
Mayer, B.J.3
Yee, K.4
Woodgett, J.R.5
Avruch, J.6
Kyriakis, J.M.7
Zon, L.I.8
-
47
-
-
0030786344
-
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase
-
Tournier C., Whitmarsh A. J., Cavanagh J., Barrett T., Davis R. J. Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase. Proc. Natl. Acad. Sci. USA. 94:1997;7337-7342.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7337-7342
-
-
Tournier, C.1
Whitmarsh, A.J.2
Cavanagh, J.3
Barrett, T.4
Davis, R.J.5
-
48
-
-
0032158987
-
ASK1 is essential for JNK/SAPK activation by TRAF2
-
Nishitoh H., Saitoh M., Mochida Y., Takeda K., Nakano H., Rothe M., Miyazono K., Ichijo H. ASK1 is essential for JNK/SAPK activation by TRAF2. Mol. Cell. 2:1998;389-395.
-
(1998)
Mol. Cell
, vol.2
, pp. 389-395
-
-
Nishitoh, H.1
Saitoh, M.2
Mochida, Y.3
Takeda, K.4
Nakano, H.5
Rothe, M.6
Miyazono, K.7
Ichijo, H.8
-
49
-
-
0033580466
-
The kinase TAK1 can activate the NIK-I κb as well as the MAP kinase cascade in the IL-1 signalling pathway
-
Ninomiya T. J., Kishimoto K., Hiyama A., Inoue J., Cao Z., Matsumoto K. The kinase TAK1 can activate the NIK-I κB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature. 398:1999;252-256.
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya, T.J.1
Kishimoto, K.2
Hiyama, A.3
Inoue, J.4
Cao, Z.5
Matsumoto, K.6
-
50
-
-
0032575591
-
Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38: Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting protein associates with a mitogen-activated protein kinase kinase kinase upstream of MKK6 and p38
-
Yuasa T., Ohno S., Kehrl J. H., Kyriakis J. M. Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38: Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting protein associates with a mitogen-activated protein kinase kinase kinase upstream of MKK6 and p38. J. Biol. Chem. 273:1998;22681-22692.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22681-22692
-
-
Yuasa, T.1
Ohno, S.2
Kehrl, J.H.3
Kyriakis, J.M.4
-
51
-
-
0031437885
-
Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-κB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2-and germinal center kinase related-dependent pathway
-
Shi C. S., Kehrl J. H. Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-κB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2-and germinal center kinase related-dependent pathway. J. Biol. Chem. 272:1997;32102-32107.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32102-32107
-
-
Shi, C.S.1
Kehrl, J.H.2
-
52
-
-
0031017618
-
MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
-
Malinin N. L., Boldin M. P., Kovalenko A. V., Wallach D. MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature. 385:1997;540-544.
-
(1997)
Nature
, vol.385
, pp. 540-544
-
-
Malinin, N.L.1
Boldin, M.P.2
Kovalenko, A.V.3
Wallach, D.4
-
53
-
-
0033611544
-
TPL-2 kinase regulates the proteolysis of the NF-κB-inhibitory protein NF-κB1 p105
-
Belich M. P., Salmeron A., Johnston L. H., Ley S. C. TPL-2 kinase regulates the proteolysis of the NF-κB-inhibitory protein NF-κB1 p105. Nature. 397:1999;363-368.
-
(1999)
Nature
, vol.397
, pp. 363-368
-
-
Belich, M.P.1
Salmeron, A.2
Johnston, L.H.3
Ley, S.C.4
-
54
-
-
0033082990
-
The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-κB acting through the NF-κB-inducing kinase and IκB kinases
-
Lin X., Cunningham E. T. Jr., Mu Y., Geleziunas R., Greene W. C. The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-κB acting through the NF-κB-inducing kinase and IκB kinases. Immunity. 10:1999;271-280.
-
(1999)
Immunity
, vol.10
, pp. 271-280
-
-
Lin, X.1
Cunningham E.T., Jr.2
Mu, Y.3
Geleziunas, R.4
Greene, W.C.5
-
55
-
-
0027332498
-
The IκB proteins: Multifunctional regulators of Rel/NF-κB transcription factors
-
Beg A. A., Baldwin A. S. Jr. The IκB proteins: Multifunctional regulators of Rel/NF-κB transcription factors. Genes Dev. 7:1993;2064-2070.
-
(1993)
Genes Dev.
, vol.7
, pp. 2064-2070
-
-
Beg, A.A.1
Baldwin A.S., Jr.2
-
56
-
-
0027333044
-
The IκB proteins: Members of a multifunctional family
-
Gilmore T. D., Morin P. J. The IκB proteins: Members of a multifunctional family. Trends Genet. 9:1993;427-433.
-
(1993)
Trends Genet.
, vol.9
, pp. 427-433
-
-
Gilmore, T.D.1
Morin, P.J.2
-
58
-
-
0027446955
-
The oncoprotein Bcl-3 directly transactivates through κb motifs via association with DNA-binding p50B homodimers
-
Bours V., Franzoso G., Azarenko V., Park S., Kanno T., Brown K., Siebenlist U. The oncoprotein Bcl-3 directly transactivates through κB motifs via association with DNA-binding p50B homodimers. Cell. 72:1993;729-739.
-
(1993)
Cell
, vol.72
, pp. 729-739
-
-
Bours, V.1
Franzoso, G.2
Azarenko, V.3
Park, S.4
Kanno, T.5
Brown, K.6
Siebenlist, U.7
-
59
-
-
0029670083
-
Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation
-
DiDonato J., Mercurio F., Rosette C., Wu-Li J., Suyang H., Ghosh S., Karin M. Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation. Mol. Cell. Biol. 16:1996;1295-1304.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1295-1304
-
-
Didonato, J.1
Mercurio, F.2
Rosette, C.3
Wu-Li, J.4
Suyang, H.5
Ghosh, S.6
Karin, M.7
-
60
-
-
0028929371
-
Coupling of a signal response domain in IκBα to multiple pathways for NF-κB activation
-
Brockman J. A., Scherer D. C., McKinsey T. A., Hall S. M., Qi X., Lee W. Y., Ballard D. W. Coupling of a signal response domain in IκBα to multiple pathways for NF-κB activation. Mol. Cell. Biol. 15:1995;2809-2818.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2809-2818
-
-
Brockman, J.A.1
Scherer, D.C.2
McKinsey, T.A.3
Hall, S.M.4
Qi, X.5
Lee, W.Y.6
Ballard, D.W.7
-
61
-
-
0028986075
-
Control of IκBα proteolysis by site-specific, signal-induced phosphorylation
-
Brown K., Gerstberger S., Carlson L., Franzoso G., Siebenlist U. Control of IκBα proteolysis by site-specific, signal-induced phosphorylation. Science. 267:1995;1485-1488.
-
(1995)
Science
, vol.267
, pp. 1485-1488
-
-
Brown, K.1
Gerstberger, S.2
Carlson, L.3
Franzoso, G.4
Siebenlist, U.5
-
62
-
-
0028978032
-
Phosphorylation of human IκBα on serines 32 and 36 controls IκBα proteolysis and NF-κB activation in response to diverse stimuli
-
Traenckner E. B., Pahl H. L., Henkel T., Schmidt K. N., Wilk S., Baeuerle P. A. Phosphorylation of human IκBα on serines 32 and 36 controls IκBα proteolysis and NF-κB activation in response to diverse stimuli. EMBO J. 14:1995;2876-2883.
-
(1995)
EMBO J.
, vol.14
, pp. 2876-2883
-
-
Traenckner, E.B.1
Pahl, H.L.2
Henkel, T.3
Schmidt, K.N.4
Wilk, S.5
Baeuerle, P.A.6
-
63
-
-
0029122799
-
N- And C-terminal sequences control degradation of MAD3/IκBα in response to inducers of NF-κB activity
-
Whiteside S. T., Ernst M. K., LeBail O., Laurent-Winter C., Rice N.m, Israel A. N- and C-terminal sequences control degradation of MAD3/IκBα in response to inducers of NF-κB activity. Mol. Cell. Biol. 15:1995;5339-5345.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5339-5345
-
-
Whiteside, S.T.1
Ernst, M.K.2
Lebail, O.3
Laurent-Winter, C.4
Rice, N.M.5
Israel, A.6
-
64
-
-
0028557348
-
Tumor necrosis factor α-induced phosphorylation of IκBα is a signal for its degradation but not dissociation from NF-κB
-
Miyamoto S., Maki M., Schmitt M. J., Hatanaka M., Verma I. M. Tumor necrosis factor α-induced phosphorylation of IκBα is a signal for its degradation but not dissociation from NF-κB. Proc. Natl. Acad. Sci. USA. 91:1994;12740-12744.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12740-12744
-
-
Miyamoto, S.1
Maki, M.2
Schmitt, M.J.3
Hatanaka, M.4
Verma, I.M.5
-
65
-
-
13044317276
-
Ubiquitin-dependent degradation of IκBα is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1
-
Hatakeyama S., Kitagawa M., Nakayama K., Shirane M., Matsumoto M., Hattori K., Higashi H., Nakano H., Okumura K., Onoe K., Good R. A., Nakayama K. Ubiquitin-dependent degradation of IκBα is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1. Proc. Natl. Acad. Sci. USA. 96:1999;3859-3863.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3859-3863
-
-
Hatakeyama, S.1
Kitagawa, M.2
Nakayama, K.3
Shirane, M.4
Matsumoto, M.5
Hattori, K.6
Higashi, H.7
Nakano, H.8
Okumura, K.9
Onoe, K.10
Good, R.A.11
Nakayama, K.12
-
66
-
-
0033083158
-
Signal-induced ubiquitination of IκBα by the F-box protein Slimb/β-TrCP
-
Spencer E., Jiang J., Chen Z. J. Signal-induced ubiquitination of IκBα by the F-box protein Slimb/β-TrCP. Genes Dev. 13:1999;284-294.
-
(1999)
Genes Dev
, vol.13
, pp. 284-294
-
-
Spencer, E.1
Jiang, J.2
Chen, Z.J.3
-
67
-
-
0033525234
-
IκBα ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box/WD40-repeat proteins, betaTrCP1 and betaTrCP2
-
Suzuki H., Chiba T., Kobayashi M., Takeuchi M., Suzuki T., Ichiyama A., Ikenoue T., Omata M., Furuichi K., Tanaka K. IκBα ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box/WD40-repeat proteins, betaTrCP1 and betaTrCP2. Biochem. Biophys. Res. Commun. 256:1999;127-132.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.256
, pp. 127-132
-
-
Suzuki, H.1
Chiba, T.2
Kobayashi, M.3
Takeuchi, M.4
Suzuki, T.5
Ichiyama, A.6
Ikenoue, T.7
Omata, M.8
Furuichi, K.9
Tanaka, K.10
-
68
-
-
0030004897
-
Site-specific phosphorylation of IκBα by a novel ubiquitination-dependent protein kinase activity
-
Chen Z. J., Parent L., Maniatis T. Site-specific phosphorylation of IκBα by a novel ubiquitination-dependent protein kinase activity. Cell. 84:1996;853-862.
-
(1996)
Cell
, vol.84
, pp. 853-862
-
-
Chen, Z.J.1
Parent, L.2
Maniatis, T.3
-
69
-
-
0030610362
-
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
-
DiDonato J. A., Hayakawa M., Rothwarf D. M., Zandi E., Karin M. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature. 388:1997;548-554.
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
Didonato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
Zandi, E.4
Karin, M.5
-
70
-
-
0031586174
-
Identification and characterization of an IκB kinase
-
Regnier C. H., Song H. Y., Gao X., Goeddel D. V., Cao Z., Rothe M. Identification and characterization of an IκB kinase. Cell. 90:1997;373-383.
-
(1997)
Cell
, vol.90
, pp. 373-383
-
-
Regnier, C.H.1
Song, H.Y.2
Gao, X.3
Goeddel, D.V.4
Cao, Z.5
Rothe, M.6
-
71
-
-
0030611595
-
IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α And NIK
-
Woronicz J. D., Gao X., Cao Z., Rothe M., Goeddel D. V. IκB kinase-β: NF-κB activation and complex formation with IκB kinase-α and NIK. Science. 278:1997;866-869.
-
(1997)
Science
, vol.278
, pp. 866-869
-
-
Woronicz, J.D.1
Gao, X.2
Cao, Z.3
Rothe, M.4
Goeddel, D.V.5
-
72
-
-
0030613551
-
The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
-
Zandi E., Rothwarf D. M., Delhase M., Hayakawa M., Karin M. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation. Cell. 91:1997;243-252.
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
Hayakawa, M.4
Karin, M.5
-
73
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
Mercurio F., Zhu H., Murray B. W., Shevchenko A., Bennett B. L., Li J., Young D. B., Barbosa M., Mann M., Manning A., Rao A. IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation. Science. 278:1997;860-866.
-
(1997)
Science
, vol.278
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevchenko, A.4
Bennett, B.L.5
Li, J.6
Young, D.B.7
Barbosa, M.8
Mann, M.9
Manning, A.10
Rao, A.11
-
74
-
-
0032583949
-
Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
-
Nakano H., Shindo M., Sakon S., Nishinaka S., Mihara M., Yagita H., Okumura K. Differential regulation of IκB kinase α and β by two upstream kinases, NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1. Proc. Natl. Acad. Sci. USA. 95:1998;3537-3542.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 3537-3542
-
-
Nakano, H.1
Shindo, M.2
Sakon, S.3
Nishinaka, S.4
Mihara, M.5
Yagita, H.6
Okumura, K.7
-
75
-
-
0033567388
-
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway
-
Kopp E., Medzhitov R., Carothers J., Xiao C., Douglas I., Janeway C. A., Ghosh S. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes Dev. 13:1999;2059-2071.
-
(1999)
Genes Dev.
, vol.13
, pp. 2059-2071
-
-
Kopp, E.1
Medzhitov, R.2
Carothers, J.3
Xiao, C.4
Douglas, I.5
Janeway, C.A.6
Ghosh, S.7
-
76
-
-
0029858387
-
TNF- And cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
-
Wang C. Y., Mayo M. W., Baldwin A. S. Jr. TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB. Science. 274:1996;784-787.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin A.S., Jr.3
-
77
-
-
0029992609
-
Suppression of TNF-α-induced apoptosis by NF-κB
-
Van Antwerp D. J., Martin S. J., Kafri T., Green D. R., Verma I. M. Suppression of TNF-α-induced apoptosis by NF-κB. Science. 274:1996;787-789.
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
78
-
-
0029976817
-
An essential role for NF-κB in preventing TNF-α-induced cell death
-
Beg A. A., Baltimore D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science. 274:1996;782-784.
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
79
-
-
0030885421
-
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control
-
Chu Z. L., McKinsey T. A., Liu L., Gentry J. J., Malim M. H., Ballard D. W. Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control. Proc. Natl. Acad. Sci. USA. 94:1997;10057-10062.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10057-10062
-
-
Chu, Z.L.1
McKinsey, T.A.2
Liu, L.3
Gentry, J.J.4
Malim, M.H.5
Ballard, D.W.6
-
80
-
-
0032508414
-
NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c- IAP2 to suppress caspase-8 activation
-
Wang C. Y., Mayo M. W., Korneluk R. G., Goeddel D. V., Baldwin A. S. Jr. NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c- IAP2 to suppress caspase-8 activation. Science. 281:1998;1680-1683.
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin A.S., Jr.5
-
81
-
-
0029073035
-
Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis
-
Sarma V., Lin Z., Clark L., Rust B. M., Tewari M., Noelle R. J., Dixit V. M. Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis. J. Biol. Chem. 270:1995;12343-12346.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12343-12346
-
-
Sarma, V.1
Lin, Z.2
Clark, L.3
Rust, B.M.4
Tewari, M.5
Noelle, R.J.6
Dixit, V.M.7
-
82
-
-
0025179989
-
The A20 cDNA induced by tumor necrosis factor α encodes a novel type of zinc finger protein
-
Opipari A. W. Jr., Boguski M. S., Dixit V. M. The A20 cDNA induced by tumor necrosis factor α encodes a novel type of zinc finger protein. J. Biol. Chem. 265:1990;14705-14708.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 14705-14708
-
-
Opipari A.W., Jr.1
Boguski, M.S.2
Dixit, V.M.3
-
83
-
-
0029917841
-
TANK, a co-inducer with TRAF2 of TNF- And CD 40L-mediated NF-κB activation
-
Cheng G., Baltimore D. TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-κB activation. Genes Dev. 10:1996;963-973.
-
(1996)
Genes Dev.
, vol.10
, pp. 963-973
-
-
Cheng, G.1
Baltimore, D.2
-
84
-
-
0029774552
-
I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction
-
Rothe M., Xiong J., Shu H. B., Williamson K., Goddard A., Goeddel D. V. I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction. Proc. Natl. Acad. Sci. USA. 93:1996;8241-8246.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8241-8246
-
-
Rothe, M.1
Xiong, J.2
Shu, H.B.3
Williamson, K.4
Goddard, A.5
Goeddel, D.V.6
-
85
-
-
0000564581
-
The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-κB activation
-
Song H. Y., Rothe M., Goeddel D. V. The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-κB activation. Proc. Natl. Acad. Sci. USA. 93:1996;6721-6725.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6721-6725
-
-
Song, H.Y.1
Rothe, M.2
Goeddel, D.V.3
-
86
-
-
0032939356
-
The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-κB activation at the level of TRAF6
-
Heyninck K., Beyaert R. The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-κB activation at the level of TRAF6. FEBS Lett. 442:1999;147-150.
-
(1999)
FEBS Lett.
, vol.442
, pp. 147-150
-
-
Heyninck, K.1
Beyaert, R.2
-
87
-
-
0347667234
-
TRAF-interacting protein (TRIP): A novel component of the tumor necrosis factor receptor (TNFR)- And CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-κB activation
-
Lee S. Y., Lee S. Y., Choi Y. TRAF-interacting protein (TRIP): A novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-κB activation. J. Exp. Med. 185:1997;1275-1285.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1275-1285
-
-
Lee, S.Y.1
Lee, S.Y.2
Choi, Y.3
-
88
-
-
0031906851
-
Peg3/Pw1 is an imprinted gene involved in the TNF-NFκB signal transduction pathway
-
Relaix F., Wei X. J., Wu X., Sassoon D. A. Peg3/Pw1 is an imprinted gene involved in the TNF-NFκB signal transduction pathway. Nature Genet. 18:1998;287-291.
-
(1998)
Nature Genet.
, vol.18
, pp. 287-291
-
-
Relaix, F.1
Wei, X.J.2
Wu, X.3
Sassoon, D.A.4
-
89
-
-
0029595282
-
The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins
-
Rothe M., Pan M. G., Henzel W. J., Ayres T. M., Goeddel D. V. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell. 83:1995;1243-1252.
-
(1995)
Cell
, vol.83
, pp. 1243-1252
-
-
Rothe, M.1
Pan, M.G.2
Henzel, W.J.3
Ayres, T.M.4
Goeddel, D.V.5
-
90
-
-
0030746740
-
Casper is a FADD- And caspase-related inducer of apoptosis
-
Shu H. B., Halpin D. R., Goeddel D. V. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity. 6:1997;751-763.
-
(1997)
Immunity
, vol.6
, pp. 751-763
-
-
Shu, H.B.1
Halpin, D.R.2
Goeddel, D.V.3
-
91
-
-
0029054725
-
RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
-
Stanger B. Z., Leder P., Lee T. H., Kim E., Seed B. RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell. 81:1995;513-523.
-
(1995)
Cell
, vol.81
, pp. 513-523
-
-
Stanger, B.Z.1
Leder, P.2
Lee, T.H.3
Kim, E.4
Seed, B.5
-
92
-
-
0029949257
-
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
-
Hsu H., Huang J., Shu H. B., Baichwal V., Goeddel D. V. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity. 4:1996;387-396.
-
(1996)
Immunity
, vol.4
, pp. 387-396
-
-
Hsu, H.1
Huang, J.2
Shu, H.B.3
Baichwal, V.4
Goeddel, D.V.5
-
93
-
-
0031463025
-
Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
-
Yeh W. C., Shahinian A., Speiser D., Kraunus J., Billia F., Wakeham A., de la Pompa J. L., Ferrick D., Hum B., Iscove N., Ohashi P., Rothe M., Goeddel D. V., Mak T. W. Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity. 7:1997;715-725.
-
(1997)
Immunity
, vol.7
, pp. 715-725
-
-
Yeh, W.C.1
Shahinian, A.2
Speiser, D.3
Kraunus, J.4
Billia, F.5
Wakeham, A.6
De La Pompa, J.L.7
Ferrick, D.8
Hum, B.9
Iscove, N.10
Ohashi, P.11
Rothe, M.12
Goeddel, D.V.13
Mak, T.W.14
-
94
-
-
0008206988
-
TRAF2 is essential for JNK but not NF-κB activation and regulates lymphocyte proliferation and survival
-
Lee S. Y., Reichlin A., Santana A., Sokol K. A., Nussenzweig M. C., Choi Y. TRAF2 is essential for JNK but not NF-κB activation and regulates lymphocyte proliferation and survival. Immunity. 7:1997;703-713.
-
(1997)
Immunity
, vol.7
, pp. 703-713
-
-
Lee, S.Y.1
Reichlin, A.2
Santana, A.3
Sokol, K.A.4
Nussenzweig, M.C.5
Choi, Y.6
-
95
-
-
0033578329
-
Targeted disruption of Traf5 gene causes defects in CD40- And CD27-mediated lymphocyte activation
-
Nakano H., Sakon S., Koseki H., Takemori T., Tada K., Matsumoto M., Munechika E., Sakai T., Shirasawa T., Akiba H., Kobata T., Santee S. M., Ware C. F., Rennert P. D., Taniguchi M., Yagita H., Okumura K. Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation. Proc. Natl. Acad. Sci. USA. 96:1999;9803-9808.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9803-9808
-
-
Nakano, H.1
Sakon, S.2
Koseki, H.3
Takemori, T.4
Tada, K.5
Matsumoto, M.6
Munechika, E.7
Sakai, T.8
Shirasawa, T.9
Akiba, H.10
Kobata, T.11
Santee, S.M.12
Ware, C.F.13
Rennert, P.D.14
Taniguchi, M.15
Yagita, H.16
Okumura, K.17
-
96
-
-
15444346943
-
CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-κB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-κB-inducing kinase
-
Akiba H., Nakano H., Nishinaka S., Shindo M., Kobata T., Atsuta M., Morimoto C., Ware C. F., Malinin N. L., Wallach D., Yagita H., Okumura K. CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-κB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-κB-inducing kinase. J. Biol. Chem. 273:1998;13353-13358.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13353-13358
-
-
Akiba, H.1
Nakano, H.2
Nishinaka, S.3
Shindo, M.4
Kobata, T.5
Atsuta, M.6
Morimoto, C.7
Ware, C.F.8
Malinin, N.L.9
Wallach, D.10
Yagita, H.11
Okumura, K.12
-
97
-
-
15144341797
-
Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFκB activation
-
Aizawa S., Nakano H., Ishida T., Horie R., Nagai M., Ito K., Yagita H., Okumura K., Inoue J., Watanabe T. Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFκB activation. J. Biol. Chem. 272:1997;2042-2045.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2042-2045
-
-
Aizawa, S.1
Nakano, H.2
Ishida, T.3
Horie, R.4
Nagai, M.5
Ito, K.6
Yagita, H.7
Okumura, K.8
Inoue, J.9
Watanabe, T.10
-
98
-
-
0032127301
-
The lymphotoxin β receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues
-
Futterer A., Mink K., Luz A., Kosco-Vilbois M. H., Pfeffer K. The lymphotoxin β receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity. 9:1998;59-70.
-
(1998)
Immunity
, vol.9
, pp. 59-70
-
-
Futterer, A.1
Mink, K.2
Luz, A.3
Kosco-Vilbois, M.H.4
Pfeffer, K.5
-
99
-
-
6544270833
-
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice
-
Naito A., Azuma S., Tanaka S., Miyazaki T., Takaki S., Takatsu K., Nakao K., Nakamura K., Katsuki M., Yamamoto T., Inoue J. I. Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice. Genes Cells. 4:1999;353-362.
-
(1999)
Genes Cells
, vol.4
, pp. 353-362
-
-
Naito, A.1
Azuma, S.2
Tanaka, S.3
Miyazaki, T.4
Takaki, S.5
Takatsu, K.6
Nakao, K.7
Nakamura, K.8
Katsuki, M.9
Yamamoto, T.10
Inoue, J.I.11
-
100
-
-
0033561039
-
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
-
Lomaga M. A., Yeh W. C., Sarosi I., Duncan G. S., Furlonger C., Ho A., Morony S., Capparelli C., Van G., Kaufman S., van der Heiden A., Itie A., Wakeham A., Khoo W., Sasaki T., Cao Z., Penninger J. M., Paige C. J., Lacey D. L., Dunstan C. R., Boyle W. J., Goeddel D. V., Mak T. W. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev. 13:1999;1015-1024.
-
(1999)
Genes Dev.
, vol.13
, pp. 1015-1024
-
-
Lomaga, M.A.1
Yeh, W.C.2
Sarosi, I.3
Duncan, G.S.4
Furlonger, C.5
Ho, A.6
Morony, S.7
Capparelli, C.8
Van, G.9
Kaufman, S.10
Van Der Heiden, A.11
Itie, A.12
Wakeham, A.13
Khoo, W.14
Sasaki, T.15
Cao, Z.16
Penninger, J.M.17
Paige, C.J.18
Lacey, D.L.19
Dunstan, C.R.20
Boyle, W.J.21
Goeddel, D.V.22
Mak, T.W.23
more..
-
101
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
-
Kong Y. Y., Yoshida H., Sarosi I., Tan H. L., Timms E., Capparelli C., Morony S., Oliveira-dos-Santos A. J., Van G., Itie A., Khoo W., Wakeham A., Dunstan C. R., Lacey D. L., Mak T. W., Boyle W. J., Penninger J. M. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature. 397:1999;315-323.
-
(1999)
Nature
, vol.397
, pp. 315-323
-
-
Kong, Y.Y.1
Yoshida, H.2
Sarosi, I.3
Tan, H.L.4
Timms, E.5
Capparelli, C.6
Morony, S.7
Oliveira-Dos-Santos, A.J.8
Van, G.9
Itie, A.10
Khoo, W.11
Wakeham, A.12
Dunstan, C.R.13
Lacey, D.L.14
Mak, T.W.15
Boyle, W.J.16
Penninger, J.M.17
-
102
-
-
15444357762
-
Requirement for NF-κB in osteoclast and B-cell development
-
Franzoso G., Carlson L., Xing L., Poljak L., Shores E. W., Brown K. D., Leonardi A., Tran T., Boyce B. F., Siebenlist U. Requirement for NF-κB in osteoclast and B-cell development. Genes Dev. 11:1997;3482-3496.
-
(1997)
Genes Dev.
, vol.11
, pp. 3482-3496
-
-
Franzoso, G.1
Carlson, L.2
Xing, L.3
Poljak, L.4
Shores, E.W.5
Brown, K.D.6
Leonardi, A.7
Tran, T.8
Boyce, B.F.9
Siebenlist, U.10
-
103
-
-
0030715563
-
Osteopetrosis in mice lacking NF-κB1 and NF-κB2
-
Iotsova V., Caamano J., Loy J., Yang Y., Lewin A., Bravo R. Osteopetrosis in mice lacking NF-κB1 and NF-κB2. Nature Med. 3:1997;1285-1289.
-
(1997)
Nature Med.
, vol.3
, pp. 1285-1289
-
-
Iotsova, V.1
Caamano, J.2
Loy, J.3
Yang, Y.4
Lewin, A.5
Bravo, R.6
-
104
-
-
0030714605
-
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
-
Anderson D. M., Maraskovsky E., Billingsley W. L., Dougall W. C., Tometsko M. E., Roux E. R., Teepe M. C., DuBose R. F., Cosman D., Galibert L. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature. 390:1997;175-179.
-
(1997)
Nature
, vol.390
, pp. 175-179
-
-
Anderson, D.M.1
Maraskovsky, E.2
Billingsley, W.L.3
Dougall, W.C.4
Tometsko, M.E.5
Roux, E.R.6
Teepe, M.C.7
Dubose, R.F.8
Cosman, D.9
Galibert, L.10
-
105
-
-
0031439265
-
TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor
-
Wong B. R., Josien R., Lee S. Y., Sauter B., Li H. L., Steinman R. M., Choi Y. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J. Exp. Med. 186:1997;2075-2080.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 2075-2080
-
-
Wong, B.R.1
Josien, R.2
Lee, S.Y.3
Sauter, B.4
Li, H.L.5
Steinman, R.M.6
Choi, Y.7
|