-
1
-
-
0028170818
-
Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease
-
Selkoe, D.J. (1994) Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease. Annu. Rev. Cell Biol. 10, 373-403.
-
(1994)
Annu. Rev. Cell Biol.
, vol.10
, pp. 373-403
-
-
Selkoe, D.J.1
-
2
-
-
0028883252
-
Molecular genetics of Alzheimer disease: Identification of genes and gene mutations
-
Van Broeckhoven, C.L. (1995) Molecular genetics of Alzheimer disease: Identification of genes and gene mutations. Eur. Neurol. 35, 8-19.
-
(1995)
Eur. Neurol.
, vol.35
, pp. 8-19
-
-
Van Broeckhoven, C.L.1
-
3
-
-
0032814135
-
Alzheimer's disease and the amyloid β protein: What is the role of amyloid?
-
Small, D.H. & McLean, C.A. (1999) Alzheimer's disease and the amyloid β protein: What is the role of amyloid? J. Neurochem. 73, 443-449.
-
(1999)
J. Neurochem.
, vol.73
, pp. 443-449
-
-
Small, D.H.1
McLean, C.A.2
-
4
-
-
0032939003
-
Amyloid precursor protein of Alzheimer's disease: Evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures
-
Storey, E., Katz, M., Brickman, Y., Beyreuther, K. & Masters, C.L. (1999) Amyloid precursor protein of Alzheimer's disease: Evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures. Eur. J. Neurosci. 11, 1779-1788.
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 1779-1788
-
-
Storey, E.1
Katz, M.2
Brickman, Y.3
Beyreuther, K.4
Masters, C.L.5
-
5
-
-
0031052381
-
Amyloid, the presenilins and Alzheimer's disease
-
Hardy, J. (1997) Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci. 20, 154-159.
-
(1997)
Trends Neurosci.
, vol.20
, pp. 154-159
-
-
Hardy, J.1
-
6
-
-
0034237719
-
Energetics in the pathogenesis of neurodegenerative diseases
-
Flint Beal, M.F. (2000) Energetics in the pathogenesis of neurodegenerative diseases. Trends Neurosci. 23, 298-304.
-
(2000)
Trends Neurosci.
, vol.23
, pp. 298-304
-
-
Flint Beal, M.F.1
-
7
-
-
0002503154
-
β-Amyloid peptides as direct cholinergic neuro-modulators: A missing link?
-
Auld, D.S., Kar, S. & Quirion, R. (1998) β-Amyloid peptides as direct cholinergic neuro-modulators: A missing link? Trends Neurosci. 21, 43-49.
-
(1998)
Trends Neurosci.
, vol.21
, pp. 43-49
-
-
Auld, D.S.1
Kar, S.2
Quirion, R.3
-
8
-
-
0006325405
-
Alzheimer's disease: A re-examination of the amyloid hypothesis
-
Neve, R.L. & Robakis, N.K. (1998) Alzheimer's disease: A re-examination of the amyloid hypothesis. Trends Neurosci. 21, 15-19.
-
(1998)
Trends Neurosci.
, vol.21
, pp. 15-19
-
-
Neve, R.L.1
Robakis, N.K.2
-
9
-
-
0033213875
-
Rationalizing a pharmacological intervention on the amyloid precursor protein metabolism
-
Racchi, M. & Govoni, S. (1999) Rationalizing a pharmacological intervention on the amyloid precursor protein metabolism. Trends Pharmacol. Sci. 20, 418-423.
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 418-423
-
-
Racchi, M.1
Govoni, S.2
-
10
-
-
0031942410
-
Regional membrane phospholipid alterations in Alzheimer's disease
-
Prasad, M.R., Lovell, M.A., Yatin, M., Dhillon, H. & Markesbery, W.R. (1998) Regional membrane phospholipid alterations in Alzheimer's disease. Neurochem. Res. 23, 81-88.
-
(1998)
Neurochem. Res.
, vol.23
, pp. 81-88
-
-
Prasad, M.R.1
Lovell, M.A.2
Yatin, M.3
Dhillon, H.4
Markesbery, W.R.5
-
11
-
-
0029559770
-
Neural membrane phospholipids in Alzheimer disease
-
Wells, K., Farookui, A.A., Liss, L. & Horrocks, L.A. (1995) Neural membrane phospholipids in Alzheimer disease. Neurochem. Res. 20, 1329-1333.
-
(1995)
Neurochem. Res.
, vol.20
, pp. 1329-1333
-
-
Wells, K.1
Farookui, A.A.2
Liss, L.3
Horrocks, L.A.4
-
12
-
-
0031745753
-
Membrane instability, plasmalogen content, and Alzheimer's disease
-
Ginsberg, L., Xuereb, J.H. & Gershfeld, N.L. (1998) Membrane instability, plasmalogen content, and Alzheimer's disease. J. Neurochem. 70, 2533-2538.
-
(1998)
J. Neurochem.
, vol.70
, pp. 2533-2538
-
-
Ginsberg, L.1
Xuereb, J.H.2
Gershfeld, N.L.3
-
13
-
-
0031740415
-
Hydrophobic mismatch between proteins and lipids in membranes
-
Killian, J.A. (1998) Hydrophobic mismatch between proteins and lipids in membranes. Biochim. Biophys. Acta 1376, 401-415.
-
(1998)
Biochim. Biophys. Acta
, vol.1376
, pp. 401-415
-
-
Killian, J.A.1
-
14
-
-
0033613129
-
Cellular mechanism of β-amyloid production and secretion
-
Sinha, S. & Lieberburg, I. (1999) Cellular mechanism of β-amyloid production and secretion. Proc. Natl. Acad. Sci. U.S.A. 96, 11049-11053.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 11049-11053
-
-
Sinha, S.1
Lieberburg, I.2
-
15
-
-
0031574374
-
Purification and spectroscopic characterization of β-amyloid precursor protein from porcine brains
-
de La Fournière-Bessueille, L., Grange, D. & Buchet, R. (1997) Purification and spectroscopic characterization of β-amyloid precursor protein from porcine brains. Eur. J. Biochem. 250, 705-711.
-
(1997)
Eur. J. Biochem.
, vol.250
, pp. 705-711
-
-
De La Fournière-Bessueille, L.1
Grange, D.2
Buchet, R.3
-
16
-
-
0032513060
-
Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. Identification of intracellular compartments in which APP cleavage occurs without using toxic agents that interfere with protein metabolism
-
Tomita, S., Kirino, Y. & Suzuki, T. (1998) Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. Identification of intracellular compartments in which APP cleavage occurs without using toxic agents that interfere with protein metabolism. J. Biol. Chem. 273, 6277-6284.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6277-6284
-
-
Tomita, S.1
Kirino, Y.2
Suzuki, T.3
-
17
-
-
0033609449
-
Cleavage of Alzheimer's amyloid precursor protein by α-secretase occurs at the surface of neuronal cells
-
Parvathy, S., Hussain, I., Karran, E.H., Turner, A.J. & Hooper, N.M. (1999) Cleavage of Alzheimer's amyloid precursor protein by α-secretase occurs at the surface of neuronal cells. Biochemistry 38, 9728-9734.
-
(1999)
Biochemistry
, vol.38
, pp. 9728-9734
-
-
Parvathy, S.1
Hussain, I.2
Karran, E.H.3
Turner, A.J.4
Hooper, N.M.5
-
18
-
-
0032983125
-
A notable cleavage: Winding up with β-amyloid
-
Kosik, K.S. (1999) A notable cleavage: Winding up with β-amyloid. Proc. Natl. Acad. Sci. U.S.A. 96, 2574-2576.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 2574-2576
-
-
Kosik, K.S.1
-
19
-
-
0032477747
-
Release of nontransmembrane full-length Alzheimer's precursor protein from the lumenal surface of chromaffin granule membranes
-
Tezapsidis, N., Li, H.-C., Ripellino, J.A., Efthimiopoulos, S., Vassilacopoulou, D., Sambamurti, K., Toneff, T., Yasothornsrikul, S., Hook, V.Y.H. & Robakis, N.K. (1998) Release of nontransmembrane full-length Alzheimer's precursor protein from the lumenal surface of chromaffin granule membranes. Biochemistry 37, 1274-1282.
-
(1998)
Biochemistry
, vol.37
, pp. 1274-1282
-
-
Tezapsidis, N.1
Li, H.-C.2
Ripellino, J.A.3
Efthimiopoulos, S.4
Vassilacopoulou, D.5
Sambamurti, K.6
Toneff, T.7
Yasothornsrikul, S.8
Hook, V.Y.H.9
Robakis, N.K.10
-
20
-
-
0033621152
-
Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's diseases
-
Wolfe, M.S., De Los Angeles, J., Miller, D.D., Xia, W. & Selkoe, D.J. (1999) Are presenilins intramembrane-cleaving proteases? Implications for the molecular mechanism of Alzheimer's diseases. Biochemistry 38, 11223-11230.
-
(1999)
Biochemistry
, vol.38
, pp. 11223-11230
-
-
Wolfe, M.S.1
De Los Angeles, J.2
Miller, D.D.3
Xia, W.4
Selkoe, D.J.5
-
21
-
-
0030720936
-
Mutations in the transmembrane domain of APP altering γ-secretase specificity
-
Lichtenthaler, S.F., Ida, N., Multhaup, G., Masters, C.L. & Beyreuther, K. (1997) Mutations in the transmembrane domain of APP altering γ-secretase specificity. Biochemistry 36, 15396-15403.
-
(1997)
Biochemistry
, vol.36
, pp. 15396-15403
-
-
Lichtenthaler, S.F.1
Ida, N.2
Multhaup, G.3
Masters, C.L.4
Beyreuther, K.5
-
22
-
-
0032502033
-
Alzheimer's amyloid precursor protein α-secretase is inhibited by hydroxamic acid-based zinc metallo-protease inhibitors: Similarities to the angiotensin converting enzyme secretase
-
Parvathy, S., Hussain, I., Karran, E.H., Turner, A.J. & Hooper, N.M. (1998) Alzheimer's amyloid precursor protein α-secretase is inhibited by hydroxamic acid-based zinc metallo-protease inhibitors: Similarities to the angiotensin converting enzyme secretase. Biochemistry 37, 1680-1685.
-
(1998)
Biochemistry
, vol.37
, pp. 1680-1685
-
-
Parvathy, S.1
Hussain, I.2
Karran, E.H.3
Turner, A.J.4
Hooper, N.M.5
-
23
-
-
0033595706
-
β-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
-
Vassar, R., Bennett, B.D., Babu-Khan, S., Kahn, S., Mendlaz, E.A., Denis, P., Teplow, D.B., Ross, S., Amarante, P., Loeloff, R., Luo, Y., Fisher, S., Fuller, J., Edenson, S., Lile, J., Jarosinski, M.A., Biere, A.L., Curran, E., Burgess, T., Louis, J.-C., Collins, F., Treanor, J., Rogers, G. & Citron, M. (1999) β-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. Science 286, 735-741.
-
(1999)
Science
, vol.286
, pp. 735-741
-
-
Vassar, R.1
Bennett, B.D.2
Babu-Khan, S.3
Kahn, S.4
Mendlaz, E.A.5
Denis, P.6
Teplow, D.B.7
Ross, S.8
Amarante, P.9
Loeloff, R.10
Luo, Y.11
Fisher, S.12
Fuller, J.13
Edenson, S.14
Lile, J.15
Jarosinski, M.A.16
Biere, A.L.17
Curran, E.18
Burgess, T.19
Louis, J.-C.20
Collins, F.21
Treanor, J.22
Rogers, G.23
Citron, M.24
more..
-
24
-
-
0033518251
-
Purification and cloning of amyloid precursor protein β-secretase from human brain
-
Sinha, S., Anderson, J.P., Barbour, R., Basi, G.S., Caccavello, R., Davis, D., Doan, M., Dovey, H.F., Frigon, N., Hong, J., Jacobson-Croak, K., Jewett, N., Keim, P., Knops, J., Lieberburg, I., Power, M., Tan, H., Tatsuno, G., Tung, J., Schenk, D., Seubert, P., Suomensaari, S.M., Wang, S., Walker, D., Zhao, J., McConlogue, L. & Varghese, J. (1999) Purification and cloning of amyloid precursor protein β-secretase from human brain. Nature 402, 537-540.
-
(1999)
Nature
, vol.402
, pp. 537-540
-
-
Sinha, S.1
Anderson, J.P.2
Barbour, R.3
Basi, G.S.4
Caccavello, R.5
Davis, D.6
Doan, M.7
Dovey, H.F.8
Frigon, N.9
Hong, J.10
Jacobson-Croak, K.11
Jewett, N.12
Keim, P.13
Knops, J.14
Lieberburg, I.15
Power, M.16
Tan, H.17
Tatsuno, G.18
Tung, J.19
Schenk, D.20
Seubert, P.21
Suomensaari, S.M.22
Wang, S.23
Walker, D.24
Zhao, J.25
McConlogue, L.26
Varghese, J.27
more..
-
25
-
-
0033518264
-
Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity
-
Yan, R., Bienkowski, M.J., Shuck, M.E., Miao, H., Tory, M.C., Pauley, A.M., Brashler, J.R., Stratman, N.C., Mathews, W.R., Buhl, A.E., Carter, D.B., Tomaselli, A.G., Parodi, L.A., Heinrikson, R.L. & Gurney, M.E. (1999) Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity Nature 402, 533-537.
-
(1999)
Nature
, vol.402
, pp. 533-537
-
-
Yan, R.1
Bienkowski, M.J.2
Shuck, M.E.3
Miao, H.4
Tory, M.C.5
Pauley, A.M.6
Brashler, J.R.7
Stratman, N.C.8
Mathews, W.R.9
Buhl, A.E.10
Carter, D.B.11
Tomaselli, A.G.12
Parodi, L.A.13
Heinrikson, R.L.14
Gurney, M.E.15
-
26
-
-
0033382226
-
Identification of a novel aspartic protease (Asp 2) as a β-secretase
-
Hussain, I., Powell, D., Hewlett, D.R., Tew, D.G., Meek, T.D., Chapman, C., Gloger, I.S., Murphy, K.E., Southan, C.D., Ryan, D.M., Smith, T.S., Simmons, D.L., Walsh, F.S., Dingwall, C. & Christie, G. (1999) Identification of a novel aspartic protease (Asp 2) as a β-secretase. Mol. Cell Neurosci. 14, 419-427.
-
(1999)
Mol. Cell Neurosci.
, vol.14
, pp. 419-427
-
-
Hussain, I.1
Powell, D.2
Hewlett, D.R.3
Tew, D.G.4
Meek, T.D.5
Chapman, C.6
Gloger, I.S.7
Murphy, K.E.8
Southan, C.D.9
Ryan, D.M.10
Smith, T.S.11
Simmons, D.L.12
Walsh, F.S.13
Dingwall, C.14
Christie, G.15
-
27
-
-
0034652309
-
Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor protein
-
Lin, X., Koelsch, G., Wu, S., Downs, D., Dashti, A. & Tang, J. (2000) Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor protein. Proc. Natl. Acad. Sci. U.S.A. 97, 1456-1460.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 1456-1460
-
-
Lin, X.1
Koelsch, G.2
Wu, S.3
Downs, D.4
Dashti, A.5
Tang, J.6
-
28
-
-
0033535553
-
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
-
Wolfe, M.S., Xia, W., Ostaszewski, B.L., Diehl, T.S., Kimberly, W.T. & Selkoe, D.J. (1999) Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity. Nature 398, 513-517.
-
(1999)
Nature
, vol.398
, pp. 513-517
-
-
Wolfe, M.S.1
Xia, W.2
Ostaszewski, B.L.3
Diehl, T.S.4
Kimberly, W.T.5
Selkoe, D.J.6
-
29
-
-
0033535504
-
A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper, B., Annaert, W., Cupers, P., Saftig, P., Craessaerts, K., Mumm, J.S., Schroeter, E.H., Schrijvers, V., Wolfe, M.S., Ray, W.J., Goate, A. & Kopan, R. (1999) A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain. Nature 398, 518-522.
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.S.6
Schroeter, E.H.7
Schrijvers, V.8
Wolfe, M.S.9
Ray, W.J.10
Goate, A.11
Kopan, R.12
-
30
-
-
0033535508
-
Presenilin is required for activity and nuclear access of Notch in Drosophila
-
Struhl, G. & Greenwald, I. (1999) Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature 398, 522-525.
-
(1999)
Nature
, vol.398
, pp. 522-525
-
-
Struhl, G.1
Greenwald, I.2
-
31
-
-
0033535555
-
Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants
-
Ye, Y., Lukinova, N. & Fortini, M.E. (1999) Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants. Nature 398, 525-529.
-
(1999)
Nature
, vol.398
, pp. 525-529
-
-
Ye, Y.1
Lukinova, N.2
Fortini, M.E.3
-
32
-
-
0034621824
-
Photoactivated γ-secretase inhibitors directed to the active site covalentiy label presenilin 1
-
Li, Y.-M., Ksu, M., Lai, M.-T., Huang, Q., Castro, J.L., DiMuzio-Mower, J., Harrison, T., Lellis, C., Nadin, A., Neduvelil, J.G., Register, R.B., Sardana, M.K., Shearman, M.S., Smith, A.L., Shi, X.-P., Yin, K.-C., Shafer, J.A. & Gardell, S.J. (2000) Photoactivated γ-secretase inhibitors directed to the active site covalentiy label presenilin 1. Nature 405, 689-694.
-
(2000)
Nature
, vol.405
, pp. 689-694
-
-
Li, Y.-M.1
Ksu, M.2
Lai, M.-T.3
Huang, Q.4
Castro, J.L.5
DiMuzio-Mower, J.6
Harrison, T.7
Lellis, C.8
Nadin, A.9
Neduvelil, J.G.10
Register, R.B.11
Sardana, M.K.12
Shearman, M.S.13
Smith, A.L.14
Shi, X.-P.15
Yin, K.-C.16
Shafer, J.A.17
Gardell, S.J.18
-
33
-
-
0030772145
-
The amyloid precursor protein is not enriched in caveolae-like, detergent-insoluble membrane microdomains
-
Parkin, E.T., Hussain, I., Turner, A.J. & Hoper, N.M. (1997) The amyloid precursor protein is not enriched in caveolae-like, detergent-insoluble membrane microdomains. J. Neurochem. 69, 2179-2188.
-
(1997)
J. Neurochem.
, vol.69
, pp. 2179-2188
-
-
Parkin, E.T.1
Hussain, I.2
Turner, A.J.3
Hoper, N.M.4
-
34
-
-
0033992140
-
Amyloid precursor protein in unique cholesterol-rich microdomains different from caveolae-like domains
-
Hayashi, H., Mizuno, T., Michikawa, M., Haass, C. & Yanagisawa, K. (2000) Amyloid precursor protein in unique cholesterol-rich microdomains different from caveolae-like domains. Biochim. Biophys. Acta 1483, 81-90.
-
(2000)
Biochim. Biophys. Acta
, vol.1483
, pp. 81-90
-
-
Hayashi, H.1
Mizuno, T.2
Michikawa, M.3
Haass, C.4
Yanagisawa, K.5
-
35
-
-
0033571721
-
Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein
-
Parkin, E.T., Turner, A.J. & Hoper, N.M. (1999) Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein. Biochem. J. 344, 23-30.
-
(1999)
Biochem. J.
, vol.344
, pp. 23-30
-
-
Parkin, E.T.1
Turner, A.J.2
Hoper, N.M.3
-
36
-
-
0032568552
-
Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons
-
Simons, M., Keller, P., De Strooper, B., Beyreuther, K., Dotti, C.G. & Simons, K. (1998) Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons. Proc. Natl. Acad. Sci. U.S.A. 95, 6460-6464.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
37
-
-
0032562615
-
Caveolae, plasma membrane microdomains for α-secretase-mediated processing of the amyloid precursor protein
-
Ikezu, T., Trapp, B.D., Song, K.S., Schlegel, A., Lisanti, M.P. & Okamoto, T. (1998) Caveolae, plasma membrane microdomains for α-secretase-mediated processing of the amyloid precursor protein. J. Biol. Chem. 273, 10485-10495.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10485-10495
-
-
Ikezu, T.1
Trapp, B.D.2
Song, K.S.3
Schlegel, A.4
Lisanti, M.P.5
Okamoto, T.6
-
38
-
-
0032480771
-
The presence of amyloid β-protein in the detergent-insoluble membrane compartment of human neuroblastoma cells
-
Morishima-Kawashima, M. & Ihara, Y. (1998) The presence of amyloid β-protein in the detergent-insoluble membrane compartment of human neuroblastoma cells. Biochemistry 37, 15247-15253.
-
(1998)
Biochemistry
, vol.37
, pp. 15247-15253
-
-
Morishima-Kawashima, M.1
Ihara, Y.2
-
39
-
-
0032999907
-
Characterization of detergentrinsoluble complexes containing the familial Alzheimer's disease-associated presenilins
-
Parkin, E.P., Hussain, I., Karran, E.H., Turner, A.J. & Hooper, N.M. (1999) Characterization of detergentrinsoluble complexes containing the familial Alzheimer's disease-associated presenilins. J. Neurochem. 72, 1534-1543.
-
(1999)
J. Neurochem.
, vol.72
, pp. 1534-1543
-
-
Parkin, E.P.1
Hussain, I.2
Karran, E.H.3
Turner, A.J.4
Hooper, N.M.5
-
40
-
-
0027447286
-
Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state
-
Pike, C.J., Burdick, D., Walencewicz, A.J., Glabe, C.G. & Cotman, C.W. (1993) Neurodegeneration induced by β-amyloid peptides in vitro: The role of peptide assembly state. J. Neurosci. 13, 1676-1687.
-
(1993)
J. Neurosci.
, vol.13
, pp. 1676-1687
-
-
Pike, C.J.1
Burdick, D.2
Walencewicz, A.J.3
Glabe, C.G.4
Cotman, C.W.5
-
41
-
-
0028265912
-
Secondary structure of amyloid β peptide correlates with neurotoxic activity in vitro
-
Simmons, L.K., May, P.C., Tomaselli, K.J., Rydel, R.E., Fuson, K.S., Brigham, E.F., Wright, S., Lieberburg, I., Becker, G.W., Brems, D.N. & Li, W.Y. (1993) Secondary structure of amyloid β peptide correlates with neurotoxic activity in vitro. Molec. Pharmacol. 45, 373-379.
-
(1993)
Molec. Pharmacol.
, vol.45
, pp. 373-379
-
-
Simmons, L.K.1
May, P.C.2
Tomaselli, K.J.3
Rydel, R.E.4
Fuson, K.S.5
Brigham, E.F.6
Wright, S.7
Lieberburg, I.8
Becker, G.W.9
Brems, D.N.10
Li, W.Y.11
-
42
-
-
17044441129
-
Conformations of synthetic β peptides in solid state and in aqueous solution: Relation to toxicity in PC12 cells
-
Buchet, R., Tavitian, E., Ristig, D., Svoboda, R., Stauss, U., Gremlich, H.U., de La Fournière, L., Staufenbiel, M., Frey, P. & Lowe, D.A. (1996) Conformations of synthetic β peptides in solid state and in aqueous solution: Relation to toxicity in PC12 cells. Biochim. Biophys. Acta 1315, 40-46.
-
(1996)
Biochim. Biophys. Acta
, vol.1315
, pp. 40-46
-
-
Buchet, R.1
Tavitian, E.2
Ristig, D.3
Svoboda, R.4
Stauss, U.5
Gremlich, H.U.6
De La Fournière, L.7
Staufenbiel, M.8
Frey, P.9
Lowe, D.A.10
-
43
-
-
0031765281
-
Membrane perturbation by neurotoxic Alzheimer amyloid fragment β25-35 requires aggregation and β-sheet formation
-
Hirakura, Y., Satoh, Y., Hirashima, N., Suzuki, T., Kagan, B.L. & Kirino, Y. (1998) Membrane perturbation by neurotoxic Alzheimer amyloid fragment β25-35 requires aggregation and β-sheet formation. Biochem. Molec. Biol. Int. 46, 787-794.
-
(1998)
Biochem. Molec. Biol. Int.
, vol.46
, pp. 787-794
-
-
Hirakura, Y.1
Satoh, Y.2
Hirashima, N.3
Suzuki, T.4
Kagan, B.L.5
Kirino, Y.6
-
44
-
-
0032562547
-
Phosphatidylinositol and inositol involvement in Alzheimer amyloid-β fibril growth and arrest
-
McLaurin, J., Franklin, T., Chakrabartty, A. & Fraser, P.E. (1998) Phosphatidylinositol and inositol involvement in Alzheimer amyloid-β fibril growth and arrest. J. Mol. Biol. 278, 183-194.
-
(1998)
J. Mol. Biol.
, vol.278
, pp. 183-194
-
-
McLaurin, J.1
Franklin, T.2
Chakrabartty, A.3
Fraser, P.E.4
-
45
-
-
0030823756
-
Acceleration of amyloid fibril formation by specific binding of Aβ-(1-40) peptide to ganglioside-containing membrane vesicles
-
Choo-Smith, L.-P., Garzon-Rodriguez, W., Glabe, C.G. & Surewicz, W.K. (1997) Acceleration of amyloid fibril formation by specific binding of Aβ-(1-40) peptide to ganglioside-containing membrane vesicles. J. Biol. Chem. 272, 22987-22990.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22987-22990
-
-
Choo-Smith, L.-P.1
Garzon-Rodriguez, W.2
Glabe, C.G.3
Surewicz, W.K.4
-
46
-
-
0033616779
-
Interactions of amyloid β-peptide (1-40) with ganglioside-containing membranes
-
Matsuzaki, K. & Horikiri, C. (1999) Interactions of amyloid β-peptide (1-40) with ganglioside-containing membranes. Biochemistry 38, 4137-4142.
-
(1999)
Biochemistry
, vol.38
, pp. 4137-4142
-
-
Matsuzaki, K.1
Horikiri, C.2
-
47
-
-
0033569981
-
Structure of the Alzheimer β-amyloid peptide (25-35) and its interaction with negatively charged phospholipid vesicles
-
del Mar Martínez-Senac, M., Villalaín, J. & Gómez-Fernández, J.C. (1999) Structure of the Alzheimer β-amyloid peptide (25-35) and its interaction with negatively charged phospholipid vesicles. Eur. J. Biochem. 265, 744-753.
-
(1999)
Eur. J. Biochem.
, vol.265
, pp. 744-753
-
-
Del Mar Martínez-Senac, M.1
Villalaín, J.2
Gómez-Fernández, J.C.3
-
48
-
-
0027508926
-
Alzheimer disease amyloid β protein forms calcium channels in bilayer membranes: Blockade by tromethamine and aluminum
-
Arispe, M., Rojas, E. & Pollard, H.B. (1993) Alzheimer disease amyloid β protein forms calcium channels in bilayer membranes: Blockade by tromethamine and aluminum. Proc. Natl. Acad. Sci. U.S.A. 90, 567-571.
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 567-571
-
-
Arispe, M.1
Rojas, E.2
Pollard, H.B.3
-
49
-
-
0033600590
-
2+-sensitive channels in reconstituted lipid vesicles
-
2+-sensitive channels in reconstituted lipid vesicles. Biochemistry 38, 11189-11196.
-
(1999)
Biochemistry
, vol.38
, pp. 11189-11196
-
-
Lin, H.1
Zhu, Y.J.2
Lal, R.3
|