Structure of the Alzheimer β-amyloid peptide (25-35) and its interaction with negatively charged phospholipid vesicles

European Journal of Biochemistry

Volumn 265, Issue 2, 1999, Pages 744-753

  Del Mar Martínez Senac, María ^a   Villalaín, José ^a   Gómez Fernández, Juan C ^a  

^a UNIVERSITY OF MURCIA   (Spain)

Author keywords

amyloid; Alzheimer's; DSC; FT IR; Phospholipid vesicles

Indexed keywords

AMPHOLYTE; AMYLOID BETA PROTEIN; GLYCEROL DERIVATIVE; PHOSPHATE; PHOSPHOLIPID; PHOSPHORYLCHOLINE; SERINE DERIVATIVE;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; ELECTRICITY; HUMAN; PH; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; TEMPERATURE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CALORIMETRY, DIFFERENTIAL SCANNING; ELECTROSTATICS; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MICROSCOPY, ELECTRON; PEPTIDE FRAGMENTS; PHOSPHOLIPIDS; PROTEIN STRUCTURE, SECONDARY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TEMPERATURE;

EID: 0033569981     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00775.x     Document Type: Article

References (45)

1. 1. Glenner, G.G. & Wong, C.W. (1984) Alzheimer's disease: initial report of the purification and characterisation of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 120, 885-890.
2. 2. Masters, C.L., Multhaup, G., Simms, G., Pottgiesser, J., Martins, R.N. & Beyreuther, K. (1985) Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels. EMBO J. 4, 2757-2763.
3. 3. Masters, C.L., Simms, G., Weinman, N.A., Multhaup, G., McDonald, B.L. & Beyreuther, K. (1985) Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc. Natl Acad. Sci. USA 82, 4245-4249.
4. 4. Selkoe, D.J. (1993) Physiological production of the β-amyloid protein and the mechanism of Alzheimer's disease. Trends Neurosci. 16, 403-409.
5. 5. Barrow, C.J. & Zagorski, M.G. (1991) Solution structure of β-peptide and its constituent fragments: relation to amyloid deposition. Science 253, 179-182.
6. 6. Kang, J., Lemaire, H.-G., Unterbeck, A., Salbaum, J.M., Masters, C.L., Grzeschik, K.-H., Multhaup, G., Beyreuther, K. & Müller-Hill, B. (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325, 733-736.
7. 7. Pike, C.J., Burdick, D., Walencewicz, A.J., Glabe, C.G. & Cotman, C.W. (1993) Neurodegeneration induced by β-amyloid peptides in vitro: the role of peptide assembly state. J. Neurosci. 13, 1676-1687.
8. 8. McLaurin, J. & Chakrabartty, A. (1996) Membrane disruption by Alzheimer β-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. J. Biol. Chem 271, 26482-26489.
9. 9. Müller, W.E., Koch, S., Eckert, A., Hartmann, H. & Scheuer, K. (1995) β-Amyloid peptide decreases membrane fluidity. Brain Res. 674, 133-136.
10. 10. Arispe, N., Pollard, H.B. & Rojas, E. (1993) Giant multilevel cation channels formed by Alzheimer disease amyloid β protein (AβP (1-40) in bilayer membranes. Proc. Natl Acad. Sci. USA 90, 10573-10577.
11. 11. Arispe, N., Rojas, E. & Pollard, H.B. (1993) Alzheimer disease amyloid β protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminium. Proc. Natl Acad. Sci. USA 90, 567-571.
12. 12. Davidson, R.M., Shajenko, L. & Donta, T.S. (1994) Amyloid beta-peptide (AβP) potentiates a nimodipine-sensitive L-type barium conductance in NIE-115 neuroblastoma cells. Brain Res. 643, 324-327.
13. 13. Walter, M.F., Mason, P.F. & Mason, R.P. (1997) Alzheimer's disease amyloid β peptide 25-35 inhibits lipid peroxidation as a result of its membrane interactions. Biochem. Biophys. Res. Commun. 233, 760-764.
14. 14. Yankner, B.A., Duffy, L.K. & Kirschner, D.A. (1990) Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science 250, 279-282.
15. 15. Terzi, E., Hölzemann, G. & Seelig, J. (1994) Alzheimer β-amyloid peptide 25-35: electrostatic interactions with phospholipid membranes. Biochemistry 33, 7434-7441.
16. 16. Van Veen, M. & O'Shea, P. (1995) The interaction of the neurodegenerative fragment of the β-amyloid peptide with phospholipid membranes. Biochem. Soc. Trans. 23, 547S.
17. 17. McLaurin, J. & Chakrabartty, A. (1997) Characterisation of the interactions of Alzheimer β-amyloid peptides with phospholipid membranes. Eur. J. Biochem. 245, 355-363.
18. 18. Hertel, C., Terzi, E., Hauser, N., Jakob-Rotne, R., Seelig, J. & Kemp, J.A. (1997) Inhibition of the electrostatic interaction between β-amyloid peptide and membranes prevents β-amyloid-induced toxicity. Proc. Natl Acad. Sci. USA 94, 9412-9416.
19. 19. Mirzabekov, T., Lin, M., Wei-long, Y., Marshal, P.J., Carman, M., Tomaselli, K., Lieberburg, I. & Kagan, B. (1994) Channel formation in planar lipid bilayers by a neurotoxic fragment of the beta-amyloid peptide. Biochem. Biophys. Res. Commun. 202, 1142-1148.
20. 20. Mason, R.P., Estermeyer, J.D., Kelly, J.F. & Mason, P.E. (1996) Alzheimer disease amyloid β peptide 25-35 is localized in the membrane hydrocarbon core: X-ray diffraction analysis. Biochem. Biophys. Res. Commun. 222, 78-82.
21. 21. Böttcher, C.J.F., Van Gent, C.M. & Fries, C. (1961) A rapid and sensitive sub-micro phosphorus determination. Anal. Chim. Acta 24, 203-204.
22. 22. Griffiths, P.R. & Pariente, G.L. (1986) Introduction to spectral deconvolution. Trends Anal. Chem. 5, 209-215.
23. 23. Krimm, S. & Bandekar, J. (1986) Vibrational spectroscopy and conformation of peptides, polypeptides, and proteins. Adv. Protein Chem. 38, 181-364.
24. 24. Arrondo, J.L.R., Muga, A., Castresana, J. & Goñi, F.M. (1993) Quantitative studies of the structure of proteins in solution by Fourier-transform infrared spectroscopy. Prog. Biophys. Mol. Biol. 59, 23-56.
25. 25. Shen, C.-L. & Murphy, R. (1995) Solvent effects on self-assembly of β-amyloid peptide. Biophys. J. 69, 640-651.
26. 26. Zhang, Y.-P., Lewis, R.N.A.H. & McElhaney, R.N. (1997) Calorimetric and spectroscopic studies of the thermotropic phase behavior of the n-saturated 1,2-diacylphosphatidylglycerols. Biophys. J. 72, 779-793.
27. 13C = O labeled phospholipids. Hydrogen bonding to carbonyl groups. Biochemistry 27, 8239-8249.
28. 28. Lewis, R.N.A.H., McElhaney, R.N., Pohle, W. & Mantsch, H.H. (1994) The components of the carbonyl stretching band in the infrared spectra of 1,2-diacylglycerolipids. A reevaluation. Biophys. J. 67, 2367-2375.
29. 29. Mantsch, H.H. & McElhaney, R.N. (1991) Phospholipid phase transitions in model and biological membranes as studied by infrared spectroscopy. Chem. Phys. Lipids 57, 213-226.
30. 30. Fraser, P.E., Nguyen, J.T., Surewicz, W.K. & Kirschner, D.A. (1991) pH-dependent structural transitions of Alzheimer amyloid peptides. Biophys. J. 60, 1190-1201.
31. 31. Hirakura, Y., Satoh, Y., Hirashima, N., Suzuki, T., Kagan, B.L. & Kirino, Y. (1998) Membrane perturbation by the neurotoxic Alzheimer amyloid fragment beta 25-35 requires aggregation and beta-sheet formation. Biochem. Mol Biol. Int. 46, 787-794.
32. 2+ on bilayers of various negatively charged phospholipids and their mixtures with phosphatidylcholine. Biochim. Biophys. Acta 512, 84-96.
33. 33. Theretz, A., Ranck, J.L. & Tocanne, J.F. (1983) Polymyxin B-induced phase separation and acyl-chain interdigitation in phosphatidylcholine/phosphatidylglycerol mixtures. Biochim. Biophys. Acta 732, 499-508.
34. 2+ and myelin basic protein. Can. J. Biochem. Cell Biol. 62, 11-18.
35. 35. Epand, R.M., Gabel, B., Epand, R.F., Sen, A., Hui, S.W., Muga, A. & Surewicz, W.K. (1992) Formation of a new stable phase of phosphatidylglycerols. Biophys. J. 63, 327-332.
36. +-bound dimyristoylphosphatidylglycerol as revealed by microcalorimetry and electron microscopy. Biochim. Biophys. Acta 1168, 243-248.
37. 37. Boggs, J.M. (1980) Intermolecular hydrogen bonding between lipids: influence on organisation and function of lipids in membranes. Can. J. Biochem. 58, 755-770.
38. 38. Boggs, J.M. (1986) Effect of lipid structural modifications on their intermolecular hydrogen bonding interactions and membrane function. Biochem. Cell Biol. 64, 50-57.
39. 39. Boggs, J.M. (1987) Lipid intermolecular hydrogen bonding: influence on structural organisation and membrane function. Biochim. Biophys. Acta 906, 353-404.
40. 40. Pascher, I., Sundell, S., Harlos, K. & Eibl, H. (1987) Conformation and packing properties of membrane lipids: the crystal structure of sodium dimyristoylphosphatidylglycerol. Biochim. Biophys. Acta 896, 77-88.
41. 41. Cevc, G. (1990) How membrane chain-melting properties are regulated by the polar surface of lipid bilayers. Biochemistry 26, 6305-6310.
42. 42. Terzi, E., Hölzemann, G. & Seelig, J. (1994) Reversible random coil-β-sheet transition of the Alzheimer β-amyloid fragment (25-35). Biochemistry 33, 1345-1350.
43. 43. Surewicz, W.K. & Epand, R.M. (1986) Phospholipid structure determines the effects of peptides on membranes. Differential scanning calorimetry studies with pentagastrin-related peptides. Biochim. Biophys. Acta 856, 290-300.
44. 44. Singh, I.N., McCartney, D.G. & Kanfer, J.N. (1995) Amyloid beta protein (25-35) stimulation of phospholipases A, C and D activities of LA-N-2 cells. FEBS Lett 365, 125-128.
45. 45. Lehtonen, Y.A., Holopainen, J.M. & Kinnunen, P.K.J. (1996) Activation of phospholipase A2 by amyloid beta-peptides in vitro. Biochemistry 35, 9407-9414.