Purification and spectroscopic characterization of β-amyloid precursor protein from porcine brains

European Journal of Biochemistry

Volumn 250, Issue 3, 1997, Pages 705-711

  De La Fournière Bessueille, Laurence ^a   Grange, Delphine ^a   Buchet, René ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Alzheimer; Amyloid precursor protein; Circular dichroism; Fourier transform infrared spectroscopy; Secondary structure

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; CIRCULAR DICHROISM; INFRARED SPECTROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; SWINE;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0031574374     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1997.00705.x     Document Type: Article

References (58)

1. Araki, W., Kitaguchi, N., Tokushima, Y., Ishii, K., Aratake, H., Shimohama, S., Nakumura, S. & Kimura, J. (1991) Trophic effect of β-amyloid precursor protein on cerebral neurons in culture, Biochem. Biophys. Res. Commun. 181, 265-271.
2. Azuaga, A. I., Sepulere, F., Padrós, E. & Mateo, P. L. (1996) Scanning calorimetry and Fourier transform infrared studies into the thermal stability of cleaved bacteriorhodopsin systems, Biochemistry 35, 16328-16355.
3. Bandekar, J. (1992) Amide modes and protein conformation, Biochim. Biophys. Acta 1120, 123-143.
4. Barrow, C. J., Yasuda, A., Kenny, P. T. M. & Zagorski, M. G. (1992) Solution conformations and aggregational properties of synthetic amyloid β-peptides of Alzheimer's disease. Analysis of circular dichroism spectra, J. Mol. Biol. 225, 1075-1093.
5. Booth, D. R., Sunde, M., Bellotti, V., Robinson, C. V., Hutchinson, W. L., Fraser, P. E., Hawkins, P. N., Dobson, C. M., Radford, S. E., Blake, C. C. F. & Pepys, M. B. (1997) Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis, Nature 385, 787-793.
6. Buchet, R., Tavitian, E., Ristig, D., Swoboda, R., Stauss, U., Gremlich, H. U., de La Fournière, L., Staufenbiel, M., Frey, P. & Lowe, D. A. (1996) Conformations of synthetic β peptides in solid state and in aqueous solution: relation to toxicity in PC12 cells, Biochim. Biophys. Acta 1315, 40-46.
7. Byler, D. M. & Susi, H. (1986) Examination of the secondary structure of proteins by deconvolved FTIR spectra, Biopolymers 25, 469-487.
8. Chirgadze, Y. N., Fedorov, O. V. & Trushina, N. P. (1975) Estimation of amino acid residue side-chain absorption in the infrared spectra of protein solutions in heavy water, Biopolymers 14, 679-694.
9. Choo, L.-P. Wetzel, D. L., Halliday, W. C., Jackson, M., LeVine, S. M. & Mantsch, H. H. (1996) In situ characterization of β-amyloid in Alzheimer's diseased tissue by synchrotron Fourier transform infrared microspectroscopy, Biophys. J. 71, 1672-1679.
10. de La Fournière, L., Nosjean, O., Buchet, R. & Roux, B. (1995) Thermal and pH stabilities of alkaline phosphatase from bovine intestinal mucosa: a FTIR study, Biochim. Biophys. Acta 1248, 186-192.
11. De Strooper, B., Van Leuven, F. & Van Den Berghe, H. (1991) The amyloid β protein precursor or proteinase nexin II from mouse is closer related to its human homolog than previously reported, Biochim. Biophys. Acta 1129, 141-143.
12. Dyrks, T., Weidemann, A., Multhaup, G., Salbaum, J. M., Lemaire, H.-G., Kang, J., Müller-Hill, B., Masters, C. L. & Beyreuther, K. (1988) Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer's disease, EMBO J. 7, 949-957.
13. Esler, W. P., Stimson, E. R., Jennings, J. M., Ghilardi, J. R., Mantyh, P. W. & Maggio, J. E. (1996) Zinc-induced aggregation of human and rat β-amyloid peptides in vitro, J. Neurochem. 66, 723-732.
14. Evin, G., Beyreuther, K. & Masters, C. L. (1994) Alzheimer's disease amyloid precursor protein (AβPP): proteolytic processing, secretases and βA4 amyloid production, Amyloid Int. J. Exp. Clin. Invest. 1, 263-280.
15. Fraser, P. E., Nguyen, J. T., Surewicz, W. K. & Kirschner, D. A. (1991) pH-dependent structural transitions of Alzheimer amyloid peptides, Biophys. J. 60, 1190-1201.
16. Fraser, S. P., Suh, Y.-H. & Djamgoz, M. B. A. (1997) Ionic effects of the Alzheimer's disease β-amyloid precursor protein and its metabolic fragments, Trends Neurosci. 20, 67-72.
17. Glasoe, P. K. & Long, F. A. (1960) Use of glass electrodes to measure acidities in deuterium oxide, J. Phys. Chem. 64, 188-190.
18. Glenner, G. G. & Wong, C. W. (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein, Biochem. Biophys. Res. Commun. 120, 885-890.
19. Goldgaber, D., Lerman, M. I., McBridge, O. W., Saffiot, U. & Gajdusek, D. C. (1987) Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease, Science 235, 877-880.
20. Goormaghtigh, E., Cabiaux, V. & Ruysschaert, J.-M. (1994) Determination of soluble and membrane protein structure by Fourier transform infrared spectroscopy. I. Assignments and model compounds, Sub-cell. Biochem. 23, 329-362.
21. Guijarro, J. I., Jackson, M., Chaffote, A. F., Delepierre, M., Mantsch, H. H. & Goldberg, M. E. (1995) Protein folding intermediates with rapidly exchangeable amide protons contain authentic hydrogen bonded secondary structures, Biochemistry 34, 2998-3008.
22. Haass, C. & Selkoe, D. J. (1993) Cellular processing of β-amyloid precursor protein and the genesis of amyloid β-peptide, Cell 75, 1039-1042.
23. Halverson, K., Fraser, P. E., Kirschner, D. A. & Lansbury, P. T. Jr (1990) Molecular determinants of amyloid deposition in Alzheimer's disease: conformational studies of synthetic β-protein fragments, Biochemistry 29, 2639-2644.
24. Hendriks, L. & Van Broeckhoven, C. (1996) The βA4 amyloid precursor protein gene and Alzheimer's disease, Eur. J. Biochem. 237, 6-15.
25. Hilbich, C., Kisters-Woike, B., Reed, J., Masters, C. L. & Beyreuther, K. (1991) Aggregation and secondary structure of synthetic amyloid βA4 peptides of Alzheimer's disease, J. Mol. Biol. 218, 149-163.
26. Hooper, N. M., Karran, E. H. & Turner, A. J. (1997) Membrane protein secretases, Biochem. J. 321, 265-279.
27. Jackson, M. & Mantsch, H. H. (1995) The use and misuse of FTIR spectroscopy in the determination of protein structure, Crit. Rev. Biochem. Mol. Biol. 30, 95-120.
28. Kang, J., Lemaire, H.-G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K.-H., Multhaup, G., Beyreuther, K. & Müller-Hill, B. (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell surface receptor, Nature 325, 733-736.
29. Kitaguchi, N., Takahashi, Y., Tokushima, Y., Shiojiri, S. & Ito, H. (1988) Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity, Nature 331, 530-532.
30. Krimm, S. & Bandekar, J. (1986) Vibrational spectroscopy and conformation of peptides, polypeptides and proteins, Adv. Protein Chem. 38, 181-386.
31. Maggio, J. E. & Mantyh, P. W. (1996) Brain amyloid - a physicochemical perspective, Brain Pathol. 6, 147-162.
32. Masters, C. L., Simms, G., Weinman, N. A., Multhaup, G., McDonald, B. L. & Beyreuther, K. (1985) Amyloid plaque core protein in Alzheimer disease and Down syndrome, Proc. Natl Acad. Sci. USA 82, 4245-4249.
33. Menéndez, M., Gasset, M., Laynez, J., López-Zumel, C., Usobiaga, P., Töpfer-Petersen, E. & Calvete, J. J. (1995) Analysis of the structural organization and thermal stability of two spermadhesins. Calorimetric, circular dichroic and Fourier-transform infrared spectroscopic studies, Eur. J. Biochem. 234, 887-896.
34. Milward, E. A., Papadopoulos, R., Fuller, S. J., Moir, R. D., Small, D., Beyreuther, K. & Masters, C. L. (1992) The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth, Neuron 9, 129-137.
35. Moir, R. D., Martins, R. N., Bush, A. I., Small, D. H., Milward, E. A., Rumble, B. A., Multhaup, G., Beyreuther, K. & Masters, C. L. (1992) Human brain A4 amyloid protein precursor of Alzheimer's disease: purification and partial characterization, J. Neurochem. 59, 1490-1498.
36. Naiki, H. & Nakakuki, K. (1996) First-order kinetic model of Alzheimer's β-amyloid fibril extension in vitro, Lab. Invest. 74, 374-383.
37. Ponte, P., Gonzalez-DeWhitt, P., Schilling, J., Miller, J., Hsu, D., Greenberg, B., Davis, K., Wallace, W., Lieberburg, I., Fuller, F. & Cordell, B. (1988) A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors, Nature 331, 525-527.
38. Potempska, A., Styles, J., Mehta, P., Kim, K. S. & Miller, D. L. (1991) Purification and tissue level of the β-amyloid peptide precursor of rat brain, J. Biol. Chem. 266, 8464-8469.
39. Provencher, S. W. & Glöckner, J. (1981) Estimation of globular protein secondary structure from circular dichroism, Biochemistry 20, 33-37.
40. Robakis, N. K., Ramakrishna, N., Wolfe, G. & Wisniewski, H. M. (1987) Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides, Proc. Natl Acad. Sci. USA 84, 4190-4194.
41. Robakis, N. K. (1994) β-amyloid and amyloid precursor protein, chemistry, molecular biology and neuropathology, in Alzheimer disease (Terry, R. D., Katzman, R. & Bick, K. L., eds) ch. 18, pp. 317-326, Raven Press, New York.
42. Sarver, R. W. & Krueger, W. C. (1991) Protein secondary structure from Fourier transform infrared spectroscopy: a data base analysis, Anal. Biochem. 194, 89-100.
43. Schubert, D., Jin, L.-W., Saitoh, T. & Cole, G. (1989) The regulation of amyloid β protein precursor secretion and its modulatory role in cell adhesion, Neuron 3, 689-694.
44. Selkoe, D. J. (1994) Cell biology of the amyloid β-protein precursor and the mechanism of Alzheimer's disease, Annu. Rev. Cell. Biol. 10, 373-403.
45. Shivers, B. D., Hilbich, C., Multhaup, G., Salbaum, M. Beyreuther, K. & Seeburg, P. H. (1988) Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact, EMBO J. 7, 1365-1370.
46. Siebert, F. (1995) Infrared spectroscopy applied to biochemical and biological problems, Methods Enzymol. 246, 501-526.
47. Sipe, J. D. (1992) Amyloidosis, Annu. Rev. Biochem. 61, 947-975.
48. Sisodia, S. S. & Price, D. L. (1995) Role of the β-amyloid protein in Alzheimer's disease, FASEB J. 9, 366-370.
49. Snyder, S. W., Ladror, U. S., Wade, W. S., Wang, G. T., Barrett, L. W., Matayoshi, E. D., Huffaker, H. J., Krafft, G. A. & Holzman, T. F. (1994) Amyloid-β aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths, Biophys. J. 67, 1216-1228.
50. Spencer, R. G. S., Halverson, K. J., Auger, M. McDermott, A. E., Griffin, R. G. & Landsbury, P. T. Jr (1991) An unusual peptide conformation may precipitate amyloid formation in Alzheimer's disease: application of solid state NMR to the determination of protein secondary structure, Biochemistry 30, 10382-10387.
51. Surewicz, W. K., Mantsch, H. H. & Chapman, D. (1993) Determination of protein secondary structure by Fourier transform infrared spectroscopy: a critical assessment, Biochemistry 32, 389-394.
52. Szendrei, G. I., Prammer, K. V., Vasko, M., Lee, V., M.-Y. & Otvos, L. Jr (1996) The effects of aspartic acid-bond isomerization on in vitro properties of the amyloid β-peptide as modeled with N-terminal decapeptide fragments, Int. J. Pept. Protein Res. 47, 289-296.
53. Tanzi, R. E., Gusella, J. F., Watkins, P. C., Bruns, G. A. P., St George-Hyslop, P., Van Keuren, M. L., Patterson, D., Pagan, S., Kurnit, D. M. & Neve, R. L. (1987) Amyloid β-protein gene: cDNA, mRNA distribution, and genetic linkage near the Alzheimer locus, Science 235, 880-884.
54. Tanzi, R. E., McClatchey, A. I., Lamperti, E. D., Villa-Komaroff, L., Gusella, J. F. & Neve, R. L. (1988) Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease, Nature 331, 528-530.
55. 2O) solutions. I. Spectral parameters of amino acid residue absorption band, Biopolymers 30, 1243-1257.
56. Venyaminov, S. Y. & Yang, J. T. (1996) Determination of protein secondary structure, in Circular dichroism and the conformational analysis of biomolecules (Fasman, G. D., ed.) pp. 69-107, Plenum Press, New York.
57. Wood, S. J., Maleeff, B., Hart, T. & Wetzel, R. (1996) Physical, morphological and functional differences between pH 5.8 and 7.4 aggregates of the Alzheimer's amyloid peptide A β, J. Mol. Biol. 256, 870-877.
58. Zagorski, M. G. & Barrow, C. J. (1992) NMR studies of amyloid β-peptides: proton assignments, secondary structure, and mechanism of an α-helix to β-sheet conversion for a homologous 28-residue, N-terminal fragment, Biochemistry 31, 5621-5631.