메뉴 건너뛰기




Volumn 12, Issue 2-3, 1998, Pages 71-79

The difference between mechanisms of kainate and glutamate excitotoxicity in vitro: Osmotic lesion versus mitochondrial depolarization

Author keywords

Apoptosis; Calcium; Depolarization; Excitotoxicity; Glutamate; Kainate; Membrane potential; Mitochondria; Neur onal death; Neurons; NMDA; Sodium

Indexed keywords

GLUTAMIC ACID; KAINIC ACID;

EID: 0031818025     PISSN: 09226028     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (24)

References (45)
  • 1
    • 0030574021 scopus 로고    scopus 로고
    • Calcineurin and mitochondrial function in glutamate-induced neuronal cell death
    • Ankarcrona, M., Dypbukt, J.M., Orrenius, S. and Nicotera, P. Calcineurin and mitochondrial function in glutamate-induced neuronal cell death. FEBS Lett. 394 (1996) 321-324.
    • (1996) FEBS Lett. , vol.394 , pp. 321-324
    • Ankarcrona, M.1    Dypbukt, J.M.2    Orrenius, S.3    Nicotera, P.4
  • 2
    • 0024990463 scopus 로고
    • Spectrin-based membrane skeleton: A multipotential adaptor between plasma membrane and cytoplasm
    • Bennett, V. Spectrin-based membrane skeleton: a multipotential adaptor between plasma membrane and cytoplasm. Physiol. Rev. 70 (1990) 1029-1065.
    • (1990) Physiol. Rev. , vol.70 , pp. 1029-1065
    • Bennett, V.1
  • 3
    • 0030008052 scopus 로고    scopus 로고
    • Superoxide production in rat hippocampal neurons: Selective imaging with hydroethidine
    • Bindokas, V.P., Jordán, J., Lee, C.C. and Miller, R.J. Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J. Neurosci. 16 (1996) 1324-1336.
    • (1996) J. Neurosci. , vol.16 , pp. 1324-1336
    • Bindokas, V.P.1    Jordán, J.2    Lee, C.C.3    Miller, R.J.4
  • 6
    • 0029827804 scopus 로고    scopus 로고
    • Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells
    • Budd, S.L. and Nicholls, D.G. Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurochem. 67 (1996 b) 2282-2291.
    • (1996) J. Neurochem. , vol.67 , pp. 2282-2291
    • Budd, S.L.1    Nicholls, D.G.2
  • 7
    • 0028210773 scopus 로고
    • 2+, and volume inside cultured adult rabbit cardiac myocytes during chemical hypoxia - A multiparameter digitized confocal microscopic study
    • 2+, and volume inside cultured adult rabbit cardiac myocytes during chemical hypoxia - a multiparameter digitized confocal microscopic study. Biophys. J. 66 (1994) 942-952.
    • (1994) Biophys. J. , vol.66 , pp. 942-952
    • Chacon, E.1    Reece, J.M.2    Nieminen, A.L.3    Zahrebelski, G.4    Herman, B.5    Lemasters, J.J.6
  • 8
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • Choi, D.W. Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7 (1987) 369-379.
    • (1987) J. Neurosci. , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 9
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi, D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1 (1988) 623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 10
    • 0026555280 scopus 로고
    • 2+-dependent changes in the mitochondrial energetics in single dissociated mouse sensory neurons
    • 2+-dependent changes in the mitochondrial energetics in single dissociated mouse sensory neurons. Biochem. J. 283 (1992) 41-50.
    • (1992) Biochem. J. , vol.283 , pp. 41-50
    • Duchen, M.R.1
  • 11
    • 0027176448 scopus 로고
    • Substrate-dependent changes in mitochondrial function, intracellular free calcium concentration and membrane changes in pancreatic β-cells
    • Duchen, M.R., Smith, P.A. and Ashcroft, F.M. Substrate-dependent changes in mitochondrial function, intracellular free calcium concentration and membrane changes in pancreatic β-cells. Biochem. J. 294 (1993) 35-42.
    • (1993) Biochem. J. , vol.294 , pp. 35-42
    • Duchen, M.R.1    Smith, P.A.2    Ashcroft, F.M.3
  • 13
    • 0027933701 scopus 로고
    • +: Implications for neurodegeneration
    • +: Implications for neurodegeneration. J. Neurochem. 63 (1994) 584-591.
    • (1994) J. Neurochem. , vol.63 , pp. 584-591
    • Dykens, J.1
  • 14
    • 0028097733 scopus 로고
    • The quantity of calcium that appears to induce neuronal death
    • Eimerl, S. and Schramm, M. The quantity of calcium that appears to induce neuronal death. J. Neurochem. 62 (1994) 1223-1226.
    • (1994) J. Neurochem. , vol.62 , pp. 1223-1226
    • Eimerl, S.1    Schramm, M.2
  • 15
    • 0022492812 scopus 로고
    • Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: Spectral and metabolic properties
    • Emaus, R.K., Grunwald, R. and Lemasters, J.J. Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim. Biophys. Acta 850 (1986) 436-448.
    • (1986) Biochim. Biophys. Acta , vol.850 , pp. 436-448
    • Emaus, R.K.1    Grunwald, R.2    Lemasters, J.J.3
  • 16
    • 0024834522 scopus 로고
    • Simultaneous imaging of cell and mitochondrial membrane potentials
    • Farkas, D.L., Wei, M., Febbroriello, P., Carson, J.H. and Loew, L.M. Simultaneous imaging of cell and mitochondrial membrane potentials. Biophys. J. 56 (1989) 1053-1069.
    • (1989) Biophys. J. , vol.56 , pp. 1053-1069
    • Farkas, D.L.1    Wei, M.2    Febbroriello, P.3    Carson, J.H.4    Loew, L.M.5
  • 17
    • 0005982327 scopus 로고
    • Selective release of glutamate from cerebellar granule cells differentiating in culture
    • Gallo, V., Ciotti, M.T., Coletti, A., Aloisi, F. and Levi, G. Selective release of glutamate from cerebellar granule cells differentiating in culture. Proc. Natl. Acad. Sci. USA 79 (1982) 7919-7923.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 7919-7923
    • Gallo, V.1    Ciotti, M.T.2    Coletti, A.3    Aloisi, F.4    Levi, G.5
  • 18
    • 0021895138 scopus 로고
    • 2+ indicators with greatly improved fluorescence properties
    • 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260 (1985) 3440-3450.
    • (1985) J. Biol. Chem. , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 19
    • 0028095807 scopus 로고
    • Mitochondrial calcium transport: Physiological and pathological relevance
    • Gunter, T.E., Gunter, K.K., Sheu, S.S. and Gavin, C.E. Mitochondrial calcium transport: physiological and pathological relevance. Am. J. Physiol. 267 (1994) C313-C339.
    • (1994) Am. J. Physiol. , vol.267
    • Gunter, T.E.1    Gunter, K.K.2    Sheu, S.S.3    Gavin, C.E.4
  • 22
    • 0021925444 scopus 로고
    • An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide
    • Jones, K.H. and Senft, J.A. An improved method to determine cell viability by simultaneous staining with fluorescein diacetate-propidium iodide. J. Histochem. Cytochem. 33 (1985) 77-79.
    • (1985) J. Histochem. Cytochem. , vol.33 , pp. 77-79
    • Jones, K.H.1    Senft, J.A.2
  • 23
    • 0025959374 scopus 로고
    • Developmental time course and ionic dependence of kainate-mediated toxicity in rat cerebellar granule cell cultures
    • Kato, K., Puttfarcken, P.S., Lyons, W.E. and Coyle, J.T. Developmental time course and ionic dependence of kainate-mediated toxicity in rat cerebellar granule cell cultures. J. Pharmacol. Exp. Ther. 256 (1991) 402-411.
    • (1991) J. Pharmacol. Exp. Ther. , vol.256 , pp. 402-411
    • Kato, K.1    Puttfarcken, P.S.2    Lyons, W.E.3    Coyle, J.T.4
  • 24
    • 0026565555 scopus 로고
    • Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells
    • Kiedrowski, L., Costa, E. and Wroblewski, J.T. Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells. J. Neurochem. 58 (1992) 335-341.
    • (1992) J. Neurochem. , vol.58 , pp. 335-341
    • Kiedrowski, L.1    Costa, E.2    Wroblewski, J.T.3
  • 25
    • 0028256101 scopus 로고
    • Glutamate impairs neuronal calcium extrusion while reducing sodium gradient
    • Kiedrowski, L., Brooker, G., Costa, E. and Wroblewski, J.T. Glutamate impairs neuronal calcium extrusion while reducing sodium gradient. Neuron 12 (1994) 295-300.
    • (1994) Neuron , vol.12 , pp. 295-300
    • Kiedrowski, L.1    Brooker, G.2    Costa, E.3    Wroblewski, J.T.4
  • 26
    • 0028842324 scopus 로고
    • Glutamate-induced destabilization of intracellular calcium concentration homeostasis in cultured cerebellar granule cells: Role of mitochondria in calcium buffering
    • Kiedrowski, L. and Costa, E. Glutamate-induced destabilization of intracellular calcium concentration homeostasis in cultured cerebellar granule cells: Role of mitochondria in calcium buffering. Molec. Pharmacol. 47 (1995) 140-147.
    • (1995) Molec. Pharmacol. , vol.47 , pp. 140-147
    • Kiedrowski, L.1    Costa, E.2
  • 27
    • 0027146417 scopus 로고
    • Imaging in five dimensions - Time-dependent membrane potentials in individual mitochondria
    • Loew, L.M., Tuft, R.A., Carrington, W. and Fay, F.S. Imaging in five dimensions - time-dependent membrane potentials in individual mitochondria. Biophys. J. 65 (1993) 2396-2407.
    • (1993) Biophys. J. , vol.65 , pp. 2396-2407
    • Loew, L.M.1    Tuft, R.A.2    Carrington, W.3    Fay, F.S.4
  • 30
    • 0023735793 scopus 로고
    • Quisqualate, high calcium concentration and zero-chloride prevent kalnate-induced toxicity of cerebellar granule cells
    • McCalslin, P.P. and Smith, T.G. Quisqualate, high calcium concentration and zero-chloride prevent kalnate-induced toxicity of cerebellar granule cells. Eur. J. Pharmacol. 152 (1988) 341-346.
    • (1988) Eur. J. Pharmacol. , vol.152 , pp. 341-346
    • McCalslin, P.P.1    Smith, T.G.2
  • 31
    • 0025166328 scopus 로고
    • Glutamate neurotoxicity in vitro: Antagonist pharmacology and intracellular calcium concentrations
    • Michaels, R.L. and Rothman, S.M. Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations. J. Neurosci. 10 (1990) 283-292.
    • (1990) J. Neurosci. , vol.10 , pp. 283-292
    • Michaels, R.L.1    Rothman, S.M.2
  • 33
    • 0022333161 scopus 로고
    • A role for the mitochondrion in the protection of cells against calcium overload?
    • Nicholls, D.G. A role for the mitochondrion in the protection of cells against calcium overload? Prog. Brain Res. 63 (1985) 97-106.
    • (1985) Prog. Brain Res. , vol.63 , pp. 97-106
    • Nicholls, D.G.1
  • 34
    • 0027295849 scopus 로고
    • Kainic acid-induced lipid peroxidation - Protection with butylated hydroxytoluene and U78517F in primary cultures of cerebellar granule cells
    • Puttfarcken, P.S., Getz, R.L. and Coyle, J.T. Kainic acid-induced lipid peroxidation - protection with butylated hydroxytoluene and U78517F in primary cultures of cerebellar granule cells. Brain Res 624 (1993) 223-232.
    • (1993) Brain Res , vol.624 , pp. 223-232
    • Puttfarcken, P.S.1    Getz, R.L.2    Coyle, J.T.3
  • 35
    • 0028126999 scopus 로고
    • Glutamate-induced intracellular calcium changes and neurotoxicity in cortical neurons in vitro: Effect of chemical ischemia
    • Rajdev, S. and Reynolds, I.J. Glutamate-induced intracellular calcium changes and neurotoxicity in cortical neurons in vitro: effect of chemical ischemia. Neuroscience 62 (1994) 667-679.
    • (1994) Neuroscience , vol.62 , pp. 667-679
    • Rajdev, S.1    Reynolds, I.J.2
  • 36
    • 0026608995 scopus 로고
    • Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
    • Randall, R.D. and Thayer, S.A. Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J. Neurosci. 12 (1992) 1882-1895.
    • (1992) J. Neurosci. , vol.12 , pp. 1882-1895
    • Randall, R.D.1    Thayer, S.A.2
  • 37
    • 0029064518 scopus 로고
    • Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
    • Reynolds, I.J. and Hastings, T.G. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J. Neurosci. (1995) 3318-3327.
    • (1995) J. Neurosci. , pp. 3318-3327
    • Reynolds, I.J.1    Hastings, T.G.2
  • 38
    • 0021880922 scopus 로고
    • The neurotoxicity of excitatory amino acids is produced by passive chloride influx
    • Rothman, S.M. The neurotoxicity of excitatory amino acids is produced by passive chloride influx. J. Neurosci. 5 (1985) 1483-1489.
    • (1985) J. Neurosci. , vol.5 , pp. 1483-1489
    • Rothman, S.M.1
  • 39
    • 0029810095 scopus 로고    scopus 로고
    • Mitochondrial dysfunction is a primary event in glutamate neurotoxicity
    • Schinder, A.F., Olson, E.C., Spitzer, N.C. and Montal, M. Mitochondrial dysfunction is a primary event in glutamate neurotoxicity. J Neurosci 16 (1996) 6125-6133.
    • (1996) J Neurosci , vol.16 , pp. 6125-6133
    • Schinder, A.F.1    Olson, E.C.2    Spitzer, N.C.3    Montal, M.4
  • 41
    • 0027497936 scopus 로고
    • Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons
    • Tymianski, M., Charlton, M.P., Carlen, P.L. and Tator, C.H. Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J. Neurosci. 13 (1993) 2085-2104.
    • (1993) J. Neurosci. , vol.13 , pp. 2085-2104
    • Tymianski, M.1    Charlton, M.P.2    Carlen, P.L.3    Tator, C.H.4
  • 42
    • 0000434165 scopus 로고    scopus 로고
    • 2+ loads by mitochondria in cultured rat hippocampal neurons
    • 2+ loads by mitochondria in cultured rat hippocampal neurons. J Neurophysiol 76 (1996) 1611-1621.
    • (1996) J Neurophysiol , vol.76 , pp. 1611-1621
    • Wang, G.J.1    Thayer, S.A.2
  • 43
    • 0028985491 scopus 로고
    • 2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons
    • 2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons. J. Neurosci. 15 (1995) 1318-1328.
    • (1995) J. Neurosci. , vol.15 , pp. 1318-1328
    • White, R.J.1    Reynolds, I.J.2
  • 44
    • 0029788243 scopus 로고    scopus 로고
    • Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure
    • White, R.J. and Reynolds, I.J. Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure. J Neurosci 16 (1996) 5688-5697.
    • (1996) J Neurosci , vol.16 , pp. 5688-5697
    • White, R.J.1    Reynolds, I.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.