Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: A model of Down's syndrome

Journal of Neuroscience

Volumn 18, Issue 18, 1998, Pages 7216-7231

  Schuchmann, Sebastian ^a   Müller, Wolfgang ^a   Heinemann, Uwe ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Alzheimer's disease; Calcium; Down's syndrome; Hippocampal culture; Mitochondrial membrane potential; NAD(P)H; Trisomy 16

Indexed keywords

CALCIUM ION; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; 2,3 DIOXO 6 NITRO 7 SULFAMOYLBENZO(F)QUINOXALINE; 2,3-DIOXO-6-NITRO-7-SULFAMOYLBENZO(F)QUINOXALINE; ALPHA TOCOPHEROL; AMINO ACID RECEPTOR BLOCKING AGENT; CALCIUM; CARCINOGEN; CYCLOSPORIN; GLUTAMIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; POTASSIUM; QUINOXALINE DERIVATIVE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN MITOCHONDRION; CALCIUM MOBILIZATION; CHROMOSOME 16; CONTROLLED STUDY; DOWN SYNDROME; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRISOMY; AGING; ANIMAL; CELL DEATH; CELL MEMBRANE POTENTIAL; CYTOLOGY; DIPLOIDY; DISEASE MODEL; DRUG EFFECT; FEMALE; GENETICS; HIPPOCAMPUS; KARYOTYPING; MALE; METABOLISM; MITOCHONDRION; MOUSE MUTANT; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGING; ALZHEIMER DISEASE; ANIMALS; CALCIUM; CARCINOGENS; CELL DEATH; CYCLOSPORINE; DIPLOIDY; DISEASE MODELS, ANIMAL; DOWN SYNDROME; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; GLUTAMIC ACID; HIPPOCAMPUS; KARYOTYPING; MALE; MEMBRANE POTENTIALS; MICE; MICE, NEUROLOGIC MUTANTS; MITOCHONDRIA; NADP; NEURONS; POTASSIUM; QUINOXALINES; SIGNAL TRANSDUCTION; TRISOMY; VITAMIN E;

EID: 0032529841     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-18-07216.1998     Document Type: Article

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