메뉴 건너뛰기




Volumn 76, Issue 3, 1996, Pages 1611-1612

Sequestration of glutamate-induced Ca2+ loads by mitochondria in cultured rat hippocampal neurons

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIMYCIN A1; BENZOTHIAZOLE; CALCIUM ION; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; COUMARIN; GLUTAMIC ACID; LACTATE DEHYDROGENASE; N METHYL DEXTRO ASPARTIC ACID; SODIUM ION;

EID: 0000434165     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1996.76.3.1611     Document Type: Article
Times cited : (153)

References (65)
  • 1
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death - A succession of necrosis or apoptosis depending on mitochondrial function
    • ANKARCRONA, M., DYPBUKT, J. M., BONFOCO, E., ZHIVOTOVSKY, B., ORRENIUS, S., LIPTON, S. A., AND NICOTERA, P. Glutamate-induced neuronal death - a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15: 961-973, 1995.
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 2
    • 0021707433 scopus 로고
    • Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
    • BENVENISTE, H., DREJER, J., SCHOUSBOE, A., AND DIEMER, N. H. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43: 1369-1374, 1984.
    • (1984) J. Neurochem. , vol.43 , pp. 1369-1374
    • Benveniste, H.1    Drejer, J.2    Schousboe, A.3    Diemer, N.H.4
  • 3
    • 0027265564 scopus 로고
    • Developmental changes in intracellular calcium regulation in rat cerebral cortex during hypoxia
    • BICKLER, P. G., GALLEGO, S. M., AND HANSER, B. M. Developmental changes in intracellular calcium regulation in rat cerebral cortex during hypoxia. J. Cereb. Blood Flow Metab. 13: 811-819, 1993.
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 811-819
    • Bickler, P.G.1    Gallego, S.M.2    Hanser, B.M.3
  • 4
    • 0030071252 scopus 로고    scopus 로고
    • A reevaluation of the role of mitochondria in neuronal Ca2+ homeostasis
    • BUDD, S. L. AND NICHOLLS, D. G. A reevaluation of the role of mitochondria in neuronal Ca2+ homeostasis. J. Neurochem. 66: 403-411, 1996.
    • (1996) J. Neurochem. , vol.66 , pp. 403-411
    • Budd, S.L.1    Nicholls, D.G.2
  • 5
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • CHOI, D. W. Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7: 369-379, 1987.
    • (1987) J. Neurosci. , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 6
  • 7
    • 0027241659 scopus 로고
    • Protective effects of ranolazine in guinea-pig hearts during low-flow ischaemia and their association with increases in active pyruvate dehydrogenase
    • CLARKE, B., SPEDDING, M., PATMORE, L., AND MCCORMACK, J. Protective effects of ranolazine in guinea-pig hearts during low-flow ischaemia and their association with increases in active pyruvate dehydrogenase. J. Pharmacol. 109: 748-750, 1993.
    • (1993) J. Pharmacol. , vol.109 , pp. 748-750
    • Clarke, B.1    Spedding, M.2    Patmore, L.3    Mccormack, J.4
  • 9
    • 0025773785 scopus 로고
    • Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures
    • DAWSON, V., DAWSON, T., LONDON, E., BREDT, D., AND SNYDER, S. Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc. Natl. Acad. Sci. USA 88: 6368-6371, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6368-6371
    • Dawson, V.1    Dawson, T.2    London, E.3    Bredt, D.4    Snyder, S.5
  • 10
    • 0026093663 scopus 로고
    • Intracellular calcium concentrations during "chemical hypoxia" and excitotoxic neuronal injury
    • DUBINSKY, J. AND ROTHMAN, S. M. Intracellular calcium concentrations during "chemical hypoxia" and excitotoxic neuronal injury. J. Neurosci. 11: 2545-2551, 1991.
    • (1991) J. Neurosci. , vol.11 , pp. 2545-2551
    • Dubinsky, J.1    Rothman, S.M.2
  • 11
    • 0028865124 scopus 로고
    • An obligate role for oxygen in the early stages of glutamate-induced, delayed neuronal death
    • DUBINSKY, J. M., KRISTAL, B. S., AND ELIZONDO-FOURNIER, M. An obligate role for oxygen in the early stages of glutamate-induced, delayed neuronal death. J. Neurosci. 15: 7071-7078, 1995.
    • (1995) J. Neurosci. , vol.15 , pp. 7071-7078
    • Dubinsky, J.M.1    Kristal, B.S.2    Elizondo-Fournier, M.3
  • 12
    • 0025345054 scopus 로고
    • Effects of metabolic blockade on the regulation of intracellular calcium in dissociated mouse sensory neurones
    • DUCHEN, M., VALDEOLMILLOS, M., AND ONEILL, S. Effects of metabolic blockade on the regulation of intracellular calcium in dissociated mouse sensory neurones. J. Physiol. Lond. 424: 411-426, 1990.
    • (1990) J. Physiol. Lond. , vol.424 , pp. 411-426
    • Duchen, M.1    Valdeolmillos, M.2    Oneill, S.3
  • 13
    • 0028882764 scopus 로고
    • Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate
    • DUGAN, L. L., SENSI, S. L., CANZONIERO, L., HANDRAN, S. D., ROTHMAN, S. M., LIN, T. S., GOLDBERG, M. P., AND CHOI, D. W. Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate. J. Neurosci. 15: 6377-6388, 1995.
    • (1995) J. Neurosci. , vol.15 , pp. 6377-6388
    • Dugan, L.L.1    Sensi, S.L.2    Canzoniero, L.3    Hran, S.D.4    Rothman, S.M.5    Lin, T.S.6    Goldberg, M.P.7    Choi, D.W.8
  • 14
    • 0027933701 scopus 로고
    • +: Implications for neurodegeneration
    • +: implications for neurodegeneration. J. Neurochem. 63: 584-591, 1994.
    • (1994) J. Neurochem. , vol.63 , pp. 584-591
    • Dykens, J.A.1
  • 15
    • 0028097733 scopus 로고
    • The quantity of calcium that appears to induce neuronal death
    • EIMERL, S. AND SCHRAMM, M. The quantity of calcium that appears to induce neuronal death. J. Neurochem. 62: 1223-1226, 1994.
    • (1994) J. Neurochem. , vol.62 , pp. 1223-1226
    • Eimerl, S.1    Schramm, M.2
  • 16
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • FADEN, A. I., DEMEDIUK, P., PANTER, S. S., AND VINK, R. The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science Wash. DC 244: 798-800, 1989.
    • (1989) Science Wash. DC , vol.244 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, R.4
  • 19
    • 0023026145 scopus 로고
    • Amino acid neurotoxicity: Intracellular sites of calcium accumulation associated with the onset of irreversible damage to rat cerebellar neurones in vitro
    • GARTHWAITE, G. AND GARTHWAITE, J. Amino acid neurotoxicity: intracellular sites of calcium accumulation associated with the onset of irreversible damage to rat cerebellar neurones in vitro. Neurosci. Lett. 71: 53-58, 1986.
    • (1986) Neurosci. Lett. , vol.71 , pp. 53-58
    • Garthwaite, G.1    Garthwaite, J.2
  • 20
    • 0021895138 scopus 로고
    • A new generation of calcium indicators with greatly improved fluorescence properties
    • GRYNKIEWICZ, G., PEONIE, M., AND TSIEN, R. Y. A new generation of calcium indicators with greatly improved fluorescence properties. J. Biol. Chem. 260: 3440-3450, 1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Peonie, M.2    Tsien, R.Y.3
  • 21
    • 0025292743 scopus 로고
    • Mechanisms by which mitochondria transport calcium
    • Cell Physiol. 27
    • GUNTER, T. E. AND PFEIFFER, D. R. Mechanisms by which mitochondria transport calcium. Am. J. Physiol. 258 (Cell Physiol. 27): C755-C786, 1990.
    • (1990) Am. J. Physiol. , vol.258
    • Gunter, T.E.1    Pfeiffer, D.R.2
  • 22
    • 0025974131 scopus 로고
    • Neurological disease and mitochondrial genes
    • HARDING, A. E. Neurological disease and mitochondrial genes. Trends Neurosci. 14: 132-138, 1991.
    • (1991) Trends Neurosci. , vol.14 , pp. 132-138
    • Harding, A.E.1
  • 23
    • 0024431210 scopus 로고
    • Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture
    • HARTLEY, D. M. AND CHOI, D. W. Delayed rescue of N-methyl-D-aspartate receptor-mediated neuronal injury in cortical culture. J. Pharmacol. Exp. Ther. 250: 752-758, 1989.
    • (1989) J. Pharmacol. Exp. Ther. , vol.250 , pp. 752-758
    • Hartley, D.M.1    Choi, D.W.2
  • 26
    • 0025922696 scopus 로고
    • 2+ from a non-mitochondrial store in an identified Helisoma neuron
    • 2+ from a non-mitochondrial store in an identified Helisoma neuron. Brain Res. 551: 311-314, 1991.
    • (1991) Brain Res. , vol.551 , pp. 311-314
    • Jensen, J.R.1    Rehder, V.2
  • 27
    • 0028316598 scopus 로고
    • Opioids mobilize calcium from inositol 1,4,5-trisphosphate-sensitive stores in NG108-15 cells
    • JIN, W. Z., LEE, N. M., LOH, H. H., AND THAYER, S. A. Opioids mobilize calcium from inositol 1,4,5-trisphosphate-sensitive stores in NG108-15 cells. J. Neurosci. 14: 1920-1929, 1994.
    • (1994) J. Neurosci. , vol.14 , pp. 1920-1929
    • Jin, W.Z.1    Lee, N.M.2    Loh, H.H.3    Thayer, S.A.4
  • 28
    • 0029099030 scopus 로고
    • Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes
    • JOUAVILLE, L. S., ICHAS, F., HOLMUHAMEDOV, E. L., CAMACHO, P., AND LECHLEITER, J. D. Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes. Nature Lond. 377: 438-441, 1995.
    • (1995) Nature Lond. , vol.377 , pp. 438-441
    • Jouaville, L.S.1    Ichas, F.2    Holmuhamedov, E.L.3    Camacho, P.4    Lechleiter, J.D.5
  • 29
    • 0028256101 scopus 로고
    • Glutamate impairs neuronal calcium extrusion while reducing sodium gradient
    • KIEDROWSKI, L., BROOKER, G., COSTA, E., AND WROBLEWSKI, J. Glutamate impairs neuronal calcium extrusion while reducing sodium gradient. Neuron 12: 295-300, 1994.
    • (1994) Neuron , vol.12 , pp. 295-300
    • Kiedrowski, L.1    Brooker, G.2    Costa, E.3    Wroblewski, J.4
  • 30
    • 0028842324 scopus 로고
    • Glutamate-induced destabilization of intracellular calcium concentration homeostasis in cultured cerebellar granule cells: Role of mitochondria in calcium buffering
    • KIEDROWSKI, L. AND COSTA, E. Glutamate-induced destabilization of intracellular calcium concentration homeostasis in cultured cerebellar granule cells: role of mitochondria in calcium buffering. Mol. Pharmacol. 47: 140-147, 1995.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 140-147
    • Kiedrowski, L.1    Costa, E.2
  • 31
    • 0023221068 scopus 로고
    • Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay
    • KOH, J. AND CHOI, D. W. Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J. Neurosci. Methods 20: 83-90, 1987.
    • (1987) J. Neurosci. Methods , vol.20 , pp. 83-90
    • Koh, J.1    Choi, D.W.2
  • 32
    • 0024424326 scopus 로고
    • 2+ concentrations in rat hippocampal slices
    • 2+ concentrations in rat hippocampal slices. Epilepsy Res. 4: 187-200, 1989.
    • (1989) Epilepsy Res. , vol.4 , pp. 187-200
    • Kohr, G.1    Heinemann, U.2
  • 33
    • 0027221998 scopus 로고
    • NMDA-dependent Superoxide production and neurotoxicity
    • LAFON-CAZAL, M., PIETRI, S., CULCASI, M., AND BOCKAERT, J. NMDA-dependent Superoxide production and neurotoxicity. Nature Lond. 364: 535-537, 1993.
    • (1993) Nature Lond. , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 34
    • 0028670473 scopus 로고
    • Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations
    • LOEW, L. M., CARRINGTON, W., TUFT, R. A., AND FAY, F. S. Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations. Proc. Natl. Acad. Sci. USA 91: 12579-83, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12579-12583
    • Loew, L.M.1    Carrington, W.2    Tuft, R.A.3    Fay, F.S.4
  • 35
    • 0027146417 scopus 로고
    • Imaging in five dimensions: Time-dependent membrane potentials in individual mitochondria
    • LOEW, L. M., TUFT, R. A., CARRINGTON, W., AND FAY, F. S. Imaging in five dimensions: time-dependent membrane potentials in individual mitochondria. Biophys. J. 65: 2396-2407, 1993.
    • (1993) Biophys. J. , vol.65 , pp. 2396-2407
    • Loew, L.M.1    Tuft, R.A.2    Carrington, W.3    Fay, F.S.4
  • 36
    • 0016148483 scopus 로고
    • Superoxide radicals as precursors of mitochondrial hydrogen peroxide
    • LOSCHEN, G., AZZI, A., RICHTER, C., AND FLOHE, L. Superoxide radicals as precursors of mitochondrial hydrogen peroxide. FEBS Lett. 42: 68-72, 1974.
    • (1974) FEBS Lett. , vol.42 , pp. 68-72
    • Loschen, G.1    Azzi, A.2    Richter, C.3    Flohe, L.4
  • 37
    • 0025328159 scopus 로고
    • Abusive stimulation of excitatory amino acid receptors: A strategy to limit neurotoxicity
    • MANEV, H., COSTA, E., WROBLEWSKI, J. T., AND GUIDOTTI, A. Abusive stimulation of excitatory amino acid receptors: a strategy to limit neurotoxicity. FASEB J. 4: 2789-2797, 1990.
    • (1990) FASEB J. , vol.4 , pp. 2789-2797
    • Manev, H.1    Costa, E.2    Wroblewski, J.T.3    Guidotti, A.4
  • 38
    • 0027058901 scopus 로고
    • Calcium-dependent cell death - Role of the endonuclease, protein kinase-C, and chromatin conformation
    • MCCABE, M. J., NICOTERA, P., AND ORRENIUS, S. Calcium-dependent cell death - role of the endonuclease, protein kinase-C, and chromatin conformation. Ann. NY Acad. Sci. 663: 269-278, 1992.
    • (1992) Ann. NY Acad. Sci. , vol.663 , pp. 269-278
    • Mccabe, M.J.1    Nicotera, P.2    Orrenius, S.3
  • 40
    • 0025319665 scopus 로고
    • Role of calcium ions in regulation of mammalian intramitochondrial metabolism
    • MCCORMACK, J. G., HALESTRAP, A. P., AND DENTON, R. M. Role of calcium ions in regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70: 391-425, 1990.
    • (1990) Physiol. Rev. , vol.70 , pp. 391-425
    • Mccormack, J.G.1    Halestrap, A.P.2    Denton, R.M.3
  • 41
    • 0025166328 scopus 로고
    • Glutamate neurotoxicity in vitro: Antagonist pharmacology and intracellular calcium concentrations
    • MICHAELS, R. L. AND ROTHMAN, S. M. Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations. J. Neurosci. 10: 283-292, 1990.
    • (1990) J. Neurosci. , vol.10 , pp. 283-292
    • Michaels, R.L.1    Rothman, S.M.2
  • 42
    • 0017178344 scopus 로고
    • Vectorial chemistry and the molecular mechanism of chemiosmotic coupling
    • MITCHELL, P. Vectorial chemistry and the molecular mechanism of chemiosmotic coupling. Biochem. Soc. Trans. 4: 399-430, 1976.
    • (1976) Biochem. Soc. Trans. , vol.4 , pp. 399-430
    • Mitchell, P.1
  • 43
    • 0024997540 scopus 로고
    • 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures
    • MONYER, H., HARTLEY, D. M., AND CHOI, D. W. 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures. Neuron 5: 121-126, 1990.
    • (1990) Neuron , vol.5 , pp. 121-126
    • Monyer, H.1    Hartley, D.M.2    Choi, D.W.3
  • 45
    • 0022333161 scopus 로고
    • A role for the mitochondrion in the protection of cells against calcium overload?
    • NICHOLLS, D. G. A role for the mitochondrion in the protection of cells against calcium overload? Prog. Brain Res. 63: 97-106, 1985.
    • (1985) Prog. Brain Res. , vol.63 , pp. 97-106
    • Nicholls, D.G.1
  • 46
    • 0014668762 scopus 로고
    • Brain lesion, obesity and other disturbances in mice treated with monosodium glutamate
    • OLNEY, J. W. Brain lesion, obesity and other disturbances in mice treated with monosodium glutamate. Science Wash. DC 164: 719-721, 1969.
    • (1969) Science Wash. DC , vol.164 , pp. 719-721
    • Olney, J.W.1
  • 47
    • 0028205221 scopus 로고
    • Changes in cytosolic sodium caused by a toxic glutamate treatment of cultured hippocampal neurons
    • PINELIS, V., SEGAL, M., GREENBERGER, V., AND KHODOROV, B. Changes in cytosolic sodium caused by a toxic glutamate treatment of cultured hippocampal neurons. Biochem. Mol. Biol. Int. 32: 475-482, 1994.
    • (1994) Biochem. Mol. Biol. Int. , vol.32 , pp. 475-482
    • Pinelis, V.1    Segal, M.2    Greenberger, V.3    Khodorov, B.4
  • 48
    • 0026608995 scopus 로고
    • Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
    • RANDALL, R. D. AND THAYER, S. A. Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons. J. Neurosci. 12: 1882-1895, 1992.
    • (1992) J. Neurosci. , vol.12 , pp. 1882-1895
    • Randall, R.D.1    Thayer, S.A.2
  • 49
    • 0029064518 scopus 로고
    • Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
    • REYNOLDS, I. J. AND HASTINGS, T. G. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J. Neurosci. 15: 3318-3327, 1995.
    • (1995) J. Neurosci. , vol.15 , pp. 3318-3327
    • Reynolds, I.J.1    Hastings, T.G.2
  • 50
    • 0018636340 scopus 로고
    • Calcium dependence of toxic cell death: A final common pathway
    • SCHANNE, F. A. X., KANE, A. B., YOUNC, E. E., AND FARBER, J. L. Calcium dependence of toxic cell death: a final common pathway. Science Wash. DC 206: 700-702, 1979.
    • (1979) Science Wash. DC , vol.206 , pp. 700-702
    • Schanne, F.A.X.1    Kane, A.B.2    Younc, E.E.3    Farber, J.L.4
  • 51
    • 0026563871 scopus 로고
    • Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82, 0715 on hippocampal cells in culture
    • SHALABY, I. A., CHENARD, B. L., PROCHNIAK, M. A., AND BUTLER, T. W. Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82, 0715 on hippocampal cells in culture. J. Pharmacol Exp. Ther. 260: 925-932, 1992.
    • (1992) J. Pharmacol Exp. Ther. , vol.260 , pp. 925-932
    • Shalaby, I.A.1    Chenard, B.L.2    Prochniak, M.A.3    Butler, T.W.4
  • 52
    • 0019842691 scopus 로고
    • Cell damage in the brain: A speculative synthesis
    • SIESJO, B. K. Cell damage in the brain: a speculative synthesis. J. Cereb. Blood Flow Metab. 1: 155-185, 1981.
    • (1981) J. Cereb. Blood Flow Metab. , vol.1 , pp. 155-185
    • Siesjo, B.K.1
  • 53
    • 0001631702 scopus 로고
    • Calcium, excitotoxins, and brain damage
    • SIESJO, B. K. Calcium, excitotoxins, and brain damage. NIPS 5: 120-125, 1990.
    • (1990) NIPS , vol.5 , pp. 120-125
    • Siesjo, B.K.1
  • 54
    • 0024363137 scopus 로고
    • Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage
    • SIMAN, R., NOSZEK, J. C., AND KEGERISE, C. Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage. J. Neurosci. 9: 1579-1590, 1989.
    • (1989) J. Neurosci. , vol.9 , pp. 1579-1590
    • Siman, R.1    Noszek, J.C.2    Kegerise, C.3
  • 55
    • 0028595636 scopus 로고
    • Regulation of intracellular calcium and calcium buffering properties of rat isolated neurohypophysial nerve endings
    • STUENKEL, E. L. Regulation of intracellular calcium and calcium buffering properties of rat isolated neurohypophysial nerve endings. J. Physiol. Lond. 481: 251-271, 1994.
    • (1994) J. Physiol. Lond. , vol.481 , pp. 251-271
    • Stuenkel, E.L.1
  • 56
    • 0025331705 scopus 로고
    • Regulation of the free intracellular calcium concentration in rat dorsal root ganglion neurones in vitro
    • THAYER, S. A. AND MILLER, R. J. Regulation of the free intracellular calcium concentration in rat dorsal root ganglion neurones in vitro. J. Physiol. Lond. 425: 85-115, 1990.
    • (1990) J. Physiol. Lond. , vol.425 , pp. 85-115
    • Thayer, S.A.1    Miller, R.J.2
  • 57
    • 0024042838 scopus 로고
    • 2+ transients using simultaneous microfluorimetry and electrophysiology
    • 2+ transients using simultaneous microfluorimetry and electrophysiology. Pfluegers Arch. 412: 216-223, 1988.
    • (1988) Pfluegers Arch. , vol.412 , pp. 216-223
    • Thayer, S.A.1    Sturek, M.2    Miller, R.J.3
  • 58
    • 0028151088 scopus 로고
    • Rapid decrease in ATP content without recovery during glutamate-induced cell death in cultured spinal neurons
    • TSUJI, K., NAKAMURA, Y., OGATA, T., SHIBATA, T., AND KATAOKA, K. Rapid decrease in ATP content without recovery during glutamate-induced cell death in cultured spinal neurons. Brain Res. 662: 289-292, 1994.
    • (1994) Brain Res. , vol.662 , pp. 289-292
    • Tsuji, K.1    Nakamura, Y.2    Ogata, T.3    Shibata, T.4    Kataoka, K.5
  • 59
    • 0027339920 scopus 로고
    • Secondary Ca2+ overload indicates early neuronal injury which precedes staining with viability indicators
    • TYMIANSKI, M. AND CHARLTON, M. P. Secondary Ca2+ overload indicates early neuronal injury which precedes staining with viability indicators. Brain Res. 1-5, 1993.
    • (1993) Brain Res. , pp. 1-5
    • Tymianski, M.1    Charlton, M.P.2
  • 61
    • 0023751240 scopus 로고
    • Beta-n-methylamino-1-alanine neurotoxicity: Requirement for bicarbonate as a cofactor
    • WEISS, J. H. AND CHOI, D. W. Beta-n-methylamino-1-alanine neurotoxicity: requirement for bicarbonate as a cofactor. Science Wash. DC 241: 973-975, 1988.
    • (1988) Science Wash. DC , vol.241 , pp. 973-975
    • Weiss, J.H.1    Choi, D.W.2
  • 62
    • 0028137817 scopus 로고
    • Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons
    • WERTH, J. L. AND THAYER, S. A. Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons. J. Neurosci. 14: 348-356, 1994.
    • (1994) J. Neurosci. , vol.14 , pp. 348-356
    • Werth, J.L.1    Thayer, S.A.2
  • 63
    • 0028174529 scopus 로고
    • 2′,3′ dideoxycytidine alters calcium buffering in cultured rat dorsal root ganglion neurons
    • WERTH, J. L., ZHOU, B., NUTTER, L. M., AND THAYER, S. A. 2′,3′ dideoxycytidine alters calcium buffering in cultured rat dorsal root ganglion neurons. Mol. Pharmacol. 45: 1119-1124, 1994.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 1119-1124
    • Werth, J.L.1    Zhou, B.2    Nutter, L.M.3    Thayer, S.A.4
  • 64
    • 0028985491 scopus 로고
    • 2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons
    • 2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons. J. Neurosci. 15: 1318-1328, 1995.
    • (1995) J. Neurosci. , vol.15 , pp. 1318-1328
    • White, R.J.1    Reynolds, I.J.2
  • 65
    • 0010324538 scopus 로고
    • Endogenous excitotoxins as possible mediators of ischemic and hypoglycemic brain damage
    • WIELOCH, T. Endogenous excitotoxins as possible mediators of ischemic and hypoglycemic brain damage. Epilepsia 26: 501, 1985.
    • (1985) Epilepsia , vol.26 , pp. 501
    • Wieloch, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.