-
1
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
1 Yu C. E., Oshima J., Fu Y. H., Wijsman E. M., Hisama F., Alisch R. et al. (1996) Positional cloning of the Werner's syndrome gene. Science 272: 258-262
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.E.1
Oshima, J.2
Fu, Y.H.3
Wijsman, E.M.4
Hisama, F.5
Alisch, R.6
-
2
-
-
0030476278
-
Werner syndrome: Entering the helicase era
-
2 Epstein C. J. and Motulsky A. G. (1996) Werner syndrome: entering the helicase era. Bioessays 18: 1025-1027
-
(1996)
Bioessays
, vol.18
, pp. 1025-1027
-
-
Epstein, C.J.1
Motulsky, A.G.2
-
3
-
-
0030861685
-
DNA helicases in inherited human disorders
-
3 Ellis N. A. (1997) DNA helicases in inherited human disorders. Curr. Opin. Genet. Dev. 7: 354-363
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 354-363
-
-
Ellis, N.A.1
-
4
-
-
0017840139
-
Genetic syndromes in man with potential relevance to the pathobiology of aging
-
4 Martin G. M. (1978) Genetic syndromes in man with potential relevance to the pathobiology of aging. Birth Defects Orig. Artic. Ser. 14: 5-39
-
(1978)
Birth Defects Orig. Artic. Ser.
, vol.14
, pp. 5-39
-
-
Martin, G.M.1
-
5
-
-
0027977269
-
It was a very good year for DNA repair
-
5 Cleaver J. E. (1994) It was a very good year for DNA repair. Cell 76: 1-4
-
(1994)
Cell
, vol.76
, pp. 1-4
-
-
Cleaver, J.E.1
-
6
-
-
0032134423
-
Xeroderma pigmentosum group C protein complex is the initialor of global genome nucleotide excision repair
-
6 Sugasawa K., Ng J. M., Masutani C., Iwai S., van der Spek P. J., Eker A. P. et al. (1998) Xeroderma pigmentosum group C protein complex is the initialor of global genome nucleotide excision repair. Mol. Cell 2: 223-232
-
(1998)
Mol. Cell
, vol.2
, pp. 223-232
-
-
Sugasawa, K.1
Ng, J.M.2
Masutani, C.3
Iwai, S.4
Van Der Spek, P.J.5
Eker, A.P.6
-
7
-
-
0027370825
-
Characterization of molecular defects in xeroderma pigmentosum group C
-
7 Li L., Bales F. S., Peterson C. A. and Legerski R. J. (1993) Characterization of molecular defects in xeroderma pigmentosum group C. Nat. Genet. 5: 413-417
-
(1993)
Nat. Genet.
, vol.5
, pp. 413-417
-
-
Li, L.1
Bales, F.S.2
Peterson, C.A.3
Legerski, R.J.4
-
8
-
-
0029609426
-
Chronological difference in walking impairment among Japanese group A xeroderma pigmentosum (XP-A) patients with various combinations of mutation sites
-
8 Maeda T., Sato K., Minami H, Taguchi H. and Yoshikawa K. (1995) Chronological difference in walking impairment among Japanese group A xeroderma pigmentosum (XP-A) patients with various combinations of mutation sites. Clin. Genel. 48: 225-231
-
(1995)
Clin. Genel.
, vol.48
, pp. 225-231
-
-
Maeda, T.1
Sato, K.2
Minami, H.3
Taguchi, H.4
Yoshikawa, K.5
-
9
-
-
0017156289
-
Relation of DNA repair processes to pathological ageing of the nervous system in xeroderma pigmentosum
-
9 Andrews A. D., Barrett S. F. and Robbins J. H. (1976) Relation of DNA repair processes to pathological ageing of the nervous system in xeroderma pigmentosum. Lancet (i): 1318-1320
-
(1976)
Lancet
, vol.1
, pp. 1318-1320
-
-
Andrews, A.D.1
Barrett, S.F.A.2
Robbins, J.H.3
-
10
-
-
0029878940
-
Truncated XPA protein detecled in atypical group A xeroderma pigmentosum
-
10 Mimaki T., Nitta M., Saijo M., Tachi N., Minami R. and Tanaka K. (1996) Truncated XPA protein detecled in atypical group A xeroderma pigmentosum. Acta. Paediatr. 85: 511-513
-
(1996)
Acta. Paediatr.
, vol.85
, pp. 511-513
-
-
Mimaki, T.1
Nitta, M.2
Saijo, M.3
Tachi, N.4
Minami, R.5
Tanaka, K.6
-
11
-
-
0030941231
-
Mutations in the XPD gene leading to xeroderma pigmentosum symptoms
-
11 Kobayashi T., Kuraoka I., Saijo M., Nakatsu Y., Tanaka A., Someda Y. et al. (1997) Mutations in the XPD gene leading to xeroderma pigmentosum symptoms. Hum. Mutat. 9: 322-331
-
(1997)
Hum. Mutat.
, vol.9
, pp. 322-331
-
-
Kobayashi, T.1
Kuraoka, I.2
Saijo, M.3
Nakatsu, Y.4
Tanaka, A.5
Someda, Y.6
-
12
-
-
0030992293
-
Loss of the xeroderma pigmentosum group A gene (XPA) enhances apoptosis of cultured cerebellar neurons induced by UV but not by low-K + medium
-
12 Enokido Y., Inamura N., Araki T., Satoh T., Nakane H., Yoshino M. et al. (1997) Loss of the xeroderma pigmentosum group A gene (XPA) enhances apoptosis of cultured cerebellar neurons induced by UV but not by low-K + medium. J. Neurochem. 69: 246-251
-
(1997)
J. Neurochem.
, vol.69
, pp. 246-251
-
-
Enokido, Y.1
Inamura, N.2
Araki, T.3
Satoh, T.4
Nakane, H.5
Yoshino, M.6
-
13
-
-
0031932262
-
Cerebellar neurodegeneration in human hereditary DNA repair disorders
-
13 Kohji T., Hayashi M., Shioda K., Minagawa M., Morimatsu Y., Tamagawa K. et al. (1998) Cerebellar neurodegeneration in human hereditary DNA repair disorders. Neurosci. Lett. 243: 133-136
-
(1998)
Neurosci. Lett.
, vol.243
, pp. 133-136
-
-
Kohji, T.1
Hayashi, M.2
Shioda, K.3
Minagawa, M.4
Morimatsu, Y.5
Tamagawa, K.6
-
14
-
-
0030745912
-
In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in xeroderma pigmentosum patients
-
14 Reardon J. T., Bessho T., Kung H. C., Bolton P. H. and Sancar A. (1997) In vitro repair of oxidative DNA damage by human nucleotide excision repair system: possible explanation for neurodegeneration in xeroderma pigmentosum patients. Proc. Natl. Acad. Sci. USA 94: 9463-9468
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9463-9468
-
-
Reardon, J.T.1
Bessho, T.2
Kung, H.C.3
Bolton, P.H.4
Sancar, A.5
-
15
-
-
0001166257
-
The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway
-
15 Wang X. W., Vermeulen W., Coursen J. D., Gibson M., Lupold S. E., Forrester K. et al. (1996) The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway. Genes Dev. 10: 1219-1232
-
(1996)
Genes Dev.
, vol.10
, pp. 1219-1232
-
-
Wang, X.W.1
Vermeulen, W.2
Coursen, J.D.3
Gibson, M.4
Lupold, S.E.5
Forrester, K.6
-
16
-
-
0033104514
-
Mutations in XPB and XPD helicases found in xeroderma pigmentosum patients impair the transcription function of TFIIH
-
16 Coin F., Bergmann E., Tremeau-Bravard A. and Egly J. M. (1999) Mutations in XPB and XPD helicases found in xeroderma pigmentosum patients impair the transcription function of TFIIH. EMBO J. 18: 1357-1366
-
(1999)
EMBO J.
, vol.18
, pp. 1357-1366
-
-
Coin, F.1
Bergmann, E.2
Tremeau-Bravard, A.3
Egly, J.M.4
-
17
-
-
0029088143
-
The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH
-
17 Henning K. A., Li L., Iyer N., McDaniel L. D., Reagan M. S., Legerski R. et al. (1995) The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell 82: 555-564
-
(1995)
Cell
, vol.82
, pp. 555-564
-
-
Henning, K.A.1
Li, L.2
Iyer, N.3
McDaniel, L.D.4
Reagan, M.S.5
Legerski, R.6
-
18
-
-
0026465665
-
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
-
18 Troelstra C., van Gool A., de Wit J., Vermeulen W., Bootsma D. and Hoeijmakers J. H. (1992) ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. Cell 71: 939-953
-
(1992)
Cell
, vol.71
, pp. 939-953
-
-
Troelstra, C.1
Van Gool, A.2
De Wit, J.3
Vermeulen, W.4
Bootsma, D.5
Hoeijmakers, J.H.6
-
19
-
-
0031020871
-
Human transcription-repair coupling factor CSB, ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II
-
19 Selby C. P. and Sancar A. (1997) Human transcription-repair coupling factor CSB, ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II. J. Biol. Chem. 272: 1885-1890
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1885-1890
-
-
Selby, C.P.1
Sancar, A.2
-
20
-
-
0030025947
-
Interactions involving the human RNA polymerase II transcription nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein
-
20 Iyer N., Reagan M. S., Wu K. J., Canagarajah B. and Friedberg E. C. (1996) Interactions involving the human RNA polymerase II transcription nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein. Biochemistry 35: 2157-2167
-
(1996)
Biochemistry
, vol.35
, pp. 2157-2167
-
-
Iyer, N.1
Reagan, M.S.2
Wu, K.J.3
Canagarajah, B.4
Friedberg, E.C.5
-
21
-
-
0029941444
-
The sensitivity of Cockayne's syndrome cells to DNA-damaging agents is not due to defective transcription-coupled repair of active genes
-
21 van Oosterwijk M. F., Versteeg A., Filon R., van Zeeland A. A. and Mullenders L. H. (1996) The sensitivity of Cockayne's syndrome cells to DNA-damaging agents is not due to defective transcription-coupled repair of active genes. Mol. Cell. Biol. 16: 4436-4444
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4436-4444
-
-
Van Oosterwijk, M.F.1
Versteeg, A.2
Filon, R.3
Van Zeeland, A.A.4
Mullenders, L.H.5
-
22
-
-
0027905008
-
DNA repair helicase: A component of BTF2 (TFIIH) basic transcription factor
-
22 Schaeffer L., Roy R., Humbert S., Moncollin V., Vermeulen W., Hoeijmakers J. H. et al. (1993) DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. Science 260: 58-63
-
(1993)
Science
, vol.260
, pp. 58-63
-
-
Schaeffer, L.1
Roy, R.2
Humbert, S.3
Moncollin, V.4
Vermeulen, W.5
Hoeijmakers, J.H.6
-
23
-
-
0030902253
-
Reduced RNA polymerase II transcription in intact and permeabilized cockayne syndrome group B cells
-
23 Balajee A. S., May A., Dianov G. L., Friedberg E. C. and Bohr V. A. (1997) Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells. Proc. Natl. Acad. Sci. USA 94: 4306-4311
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4306-4311
-
-
Balajee, A.S.1
May, A.2
Dianov, G.L.3
Friedberg, E.C.4
Bohr, V.A.5
-
24
-
-
0027174179
-
DNA repair: Engagement with transcription
-
24 Bootsma D. and Hoeijmakers J. H. (1993) DNA repair: engagement with transcription. Nature 363: 114-115
-
(1993)
Nature
, vol.363
, pp. 114-115
-
-
Bootsma, D.1
Hoeijmakers, J.H.2
-
25
-
-
0028673969
-
Three unusual repair deficiencies associated with transcription factor BTF2 (TFIIH): Evidence for the existence of a transcription syndrome
-
25 Vermeulen W., van Vuuren A. J., Chipoulet M., Schaeffer L., Appeldoorn E., Weeda G. et al. (1994) Three unusual repair deficiencies associated with transcription factor BTF2 (TFIIH): evidence for the existence of a transcription syndrome. Cold Spring Harb. Symp. Quant. Biol. 59: 317-329
-
(1994)
Cold Spring Harb. Symp. Quant. Biol.
, vol.59
, pp. 317-329
-
-
Vermeulen, W.1
Van Vuuren, A.J.2
Chipoulet, M.3
Schaeffer, L.4
Appeldoorn, E.5
Weeda, G.6
-
26
-
-
0029850732
-
Cockayne syndrome a primary defect in DNA repair, transcription, both or neither?
-
26 Friedberg E. C. (1996) Cockayne syndrome a primary defect in DNA repair, transcription, both or neither? Bioessays 18: 731-738
-
(1996)
Bioessays
, vol.18
, pp. 731-738
-
-
Friedberg, E.C.1
-
27
-
-
0030739911
-
The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor
-
27 Weeda G., Rossignol M., Fraser R. A., Winkler G. S., Vermeulen W., van't Veer L. J. et al. (1997) The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor. Nucleic Acids Res. 25: 2274-2283
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2274-2283
-
-
Weeda, G.1
Rossignol, M.2
Fraser, R.A.3
Winkler, G.S.4
Vermeulen, W.5
Van't Veer, L.J.6
-
28
-
-
0028890361
-
Interaction of thyroid-hormone receptor with a conserved transcriptional mediator
-
28 Lee J. W., Ryan F., Swaffield J. C., Johnston S. A. and Moore D. D. (1995) Interaction of thyroid-hormone receptor with a conserved transcriptional mediator. Nature 374: 91-94
-
(1995)
Nature
, vol.374
, pp. 91-94
-
-
Lee, J.W.1
Ryan, F.2
Swaffield, J.C.3
Johnston, S.A.4
Moore, D.D.5
-
29
-
-
0030948085
-
SUG1, a putative transcriptional mediator and subunit of the PA700 proteasome regulatory complex, is a DNA helicase
-
29 Fraser R. A., Rossignol M., Heard D. J., Egly J. M. and Chambon P. (1997) SUG1, a putative transcriptional mediator and subunit of the PA700 proteasome regulatory complex, is a DNA helicase. J. Biol. Chem. 272: 7122-7126
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7122-7126
-
-
Fraser, R.A.1
Rossignol, M.2
Heard, D.J.3
Egly, J.M.4
Chambon, P.5
-
30
-
-
0030990434
-
A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: Implications for a second XPG function
-
30 Nouspikel T., Lalle P., Leadon S. A., Cooper P. K. and Clarkson S. G. (1997) A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: implications for a second XPG function. Proc. Natl. Acad. Sci. USA 94: 3116-3121
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3116-3121
-
-
Nouspikel, T.1
Lalle, P.2
Leadon, S.A.3
Cooper, P.K.4
Clarkson, S.G.5
-
31
-
-
0031025997
-
Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G
-
31 Cooper P. K., Nouspikel T., Clarkson S. G. and Leadon S. A. (1997) Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G. Science 275: 990-993
-
(1997)
Science
, vol.275
, pp. 990-993
-
-
Cooper, P.K.1
Nouspikel, T.2
Clarkson, S.G.3
Leadon, S.A.4
-
32
-
-
0027379353
-
Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome
-
32 Leadon S. A. and Cooper P. K. (1993) Preferential repair of ionizing radiation-induced damage in the transcribed strand of an active human gene is defective in Cockayne syndrome. Proc. Natl. Acad. Sci. USA 90: 10499-10503
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10499-10503
-
-
Leadon, S.A.1
Cooper, P.K.2
-
33
-
-
0029887819
-
Transcription-coupled repair deficiency and mutations in human mismatch repair genes
-
33 Mellon I., Rajpal D. K., Koi M., Boland C. R. and Champe G. N. (1996) Transcription-coupled repair deficiency and mutations in human mismatch repair genes. Science 272: 557-560
-
(1996)
Science
, vol.272
, pp. 557-560
-
-
Mellon, I.1
Rajpal, D.K.2
Koi, M.3
Boland, C.R.4
Champe, G.N.5
-
34
-
-
0001166257
-
The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway
-
34 Wang X. W., Vermeulen W., Coursen J. D., Gibson M., Lupold S. E., Forrester K. et al. (1996) The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway. Genes Dev. 10: 1219-1232
-
(1996)
Genes Dev.
, vol.10
, pp. 1219-1232
-
-
Wang, X.W.1
Vermeulen, W.2
Coursen, J.D.3
Gibson, M.4
Lupold, S.E.5
Forrester, K.6
-
35
-
-
0030916337
-
Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition
-
35 van der Horst G. T., van Steeg H., Berg R. J., van Gool A. J., de Wit J., Weeda G. et al. (1997) Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition. Cell 89: 425-435
-
(1997)
Cell
, vol.89
, pp. 425-435
-
-
Van Der Horst, G.T.1
Van Steeg, H.2
Berg, R.J.3
Van Gool, A.J.4
De Wit, J.5
Weeda, G.6
-
36
-
-
0023188281
-
Complementation studies in cells from patients affected by trichothiodystrophy with normal or enhanced UV photosensitivity
-
36 Stefanini M., Lagomarsini P., Giorgi R. and Nuzzo F. (1987) Complementation studies in cells from patients affected by trichothiodystrophy with normal or enhanced UV photosensitivity. Mutat. Res. 191: 117-119
-
(1987)
Mutat. Res.
, vol.191
, pp. 117-119
-
-
Stefanini, M.1
Lagomarsini, P.2
Giorgi, R.3
Nuzzo, F.4
-
37
-
-
0023763193
-
Trichothiodystrophy, a human DNA repair disorder with heterogeneity in the cellular response to ultraviolet light
-
37 Lehmann A. R., Arlett C. F., Broughton B. C., Harcourt S. A., Steingrimsdoltir H., Stefanini M. et al. (1988) Trichothiodystrophy, a human DNA repair disorder with heterogeneity in the cellular response to ultraviolet light. Cancer Res. 48: 6090-6096
-
(1988)
Cancer Res.
, vol.48
, pp. 6090-6096
-
-
Lehmann, A.R.1
Arlett, C.F.2
Broughton, B.C.3
Harcourt, S.A.4
Steingrimsdoltir, H.5
Stefanini, M.6
-
38
-
-
0026543076
-
DNA repair investigations in nine Italian patients affected by trichothiodystrophy
-
38 Stefanini M., Giliani S., Nardo T., Marinoni S., Nazzaro V., Rizzo R. et al. (1992) DNA repair investigations in nine Italian patients affected by trichothiodystrophy. Mutat. Res. 273: 119-125
-
(1992)
Mutat. Res.
, vol.273
, pp. 119-125
-
-
Stefanini, M.1
Giliani, S.2
Nardo, T.3
Marinoni, S.4
Nazzaro, V.5
Rizzo, R.6
-
39
-
-
0027440658
-
A new nucleotide-excision-repair gene associated with the disorder trichothiodystrophy
-
39 Stefanini M., Vermeulen W., Weeda G., Giliani S., Nardo T., Mezzina M. et al. (1993) A new nucleotide-excision-repair gene associated with the disorder trichothiodystrophy. Am. J. Hum. Genet. 53: 817-821
-
(1993)
Am. J. Hum. Genet.
, vol.53
, pp. 817-821
-
-
Stefanini, M.1
Vermeulen, W.2
Weeda, G.3
Giliani, S.4
Nardo, T.5
Mezzina, M.6
-
40
-
-
16944363270
-
A mutation in the XPB/ERCC3 DNA repair transcription gene, associated with trichothiodystrophy
-
40 Weeda G., Eveno E., Donker I., Vermeulen W., Chevallier-Lagente O., Taieb A. et al. (1997) A mutation in the XPB/ERCC3 DNA repair transcription gene, associated with trichothiodystrophy. Am. J. Hum. Genet. 60: 320-329
-
(1997)
Am. J. Hum. Genet.
, vol.60
, pp. 320-329
-
-
Weeda, G.1
Eveno, E.2
Donker, I.3
Vermeulen, W.4
Chevallier-Lagente, O.5
Taieb, A.6
-
41
-
-
0032085182
-
A mouse model for the basal transcription/DNA repair syndrome triehothiodystrophy
-
41 de Boer J., de Wit J., van Steeg H., Berg R. J., Morreau H., Visser P. et al. (1998) A mouse model for the basal transcription/DNA repair syndrome triehothiodystrophy. Mol. Cell 1: 981-990
-
(1998)
Mol. Cell
, vol.1
, pp. 981-990
-
-
De Boer, J.1
De Wit, J.2
Van Steeg, H.3
Berg, R.J.4
Morreau, H.5
Visser, P.6
-
42
-
-
12644310290
-
Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD (ERCC2) rcpair/transcription gene
-
42 Taylor E. M., Broughton B. C., Botta E., Stefanini M., Sarasin A., Jaspers N. G. et al. (1997) Xeroderma pigmentosum and trichothiodystrophy are associated with different mutations in the XPD (ERCC2) rcpair/transcription gene. Proc. Natl. Acad. Sci. USA 94: 8658-8663
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 8658-8663
-
-
Taylor, E.M.1
Broughton, B.C.2
Botta, E.3
Stefanini, M.4
Sarasin, A.5
Jaspers, N.G.6
-
43
-
-
0032231836
-
Analysis of mutations in the XPD gene in Italian patients with trichothiodystrophy: Site of mutation correlates with repair deficiency, but gene dosage appears to determine clinical severity
-
43 Botta E., Nardo T., Broughton B. C., Marinoni S., Lehmann A. R. and Stefanini M. (1998) Analysis of mutations in the XPD gene in Italian patients with trichothiodystrophy: site of mutation correlates with repair deficiency, but gene dosage appears to determine clinical severity. Am. J. Hum. Genet. 63: 1036-1048
-
(1998)
Am. J. Hum. Genet.
, vol.63
, pp. 1036-1048
-
-
Botta, E.1
Nardo, T.2
Broughton, B.C.3
Marinoni, S.4
Lehmann, A.R.5
Stefanini, M.6
-
44
-
-
0028358988
-
Mutations in the xeroderma pigmentosum group D DNA repair/transcription gene in patients with trichothiodystrophy
-
44 Broughton B. C., Steingrimsdottir H., Weber C. A. and Lehmann A. R. (1994) Mutations in the xeroderma pigmentosum group D DNA repair/transcription gene in patients with trichothiodystrophy. Nat. Genet. 7: 189-194
-
(1994)
Nat. Genet.
, vol.7
, pp. 189-194
-
-
Broughton, B.C.1
Steingrimsdottir, H.2
Weber, C.A.3
Lehmann, A.R.4
-
45
-
-
0030945874
-
DNA repair characteristics and mutations in the ERCC2 DNA repair and transcription gene in a trichothiodystrophy patient
-
45 Takayama K., Danks D. M., Salazar E. P., Cleaver J. E. and Weber C. A. (1997) DNA repair characteristics and mutations in the ERCC2 DNA repair and transcription gene in a trichothiodystrophy patient. Hum. Mutat. 9: 519-525
-
(1997)
Hum. Mutat.
, vol.9
, pp. 519-525
-
-
Takayama, K.1
Danks, D.M.2
Salazar, E.P.3
Cleaver, J.E.4
Weber, C.A.5
-
46
-
-
0031666241
-
Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH
-
46 Coin F., Marinoni J. C., Rodolfo C., Fribourg S., Pedrini A. M. and Egly J. M. (1998) Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH. Nat. Genet. 20: 184-188
-
(1998)
Nat. Genet.
, vol.20
, pp. 184-188
-
-
Coin, F.1
Marinoni, J.C.2
Rodolfo, C.3
Fribourg, S.4
Pedrini, A.M.5
Egly, J.M.6
-
47
-
-
0024407431
-
Joining of linear plasmid DNA is reduced and error-prone in Bloom's syndrome cells
-
47 Runger T. M. and Kraemer K. H. (1989) Joining of linear plasmid DNA is reduced and error-prone in Bloom's syndrome cells. EMBO J. 8: 1419-1425
-
(1989)
EMBO J.
, vol.8
, pp. 1419-1425
-
-
Runger, T.M.1
Kraemer, K.H.2
-
48
-
-
0030826311
-
Characterization of a new BLM mutation associated with a topoisomerase II alpha defect in a patient with Bloom's syndrome
-
48 Foucault F., Vaury C., Barakat A., Thibout D., Planchon P., Jaulin C. et al. (1997)Characterization of a new BLM mutation associated with a topoisomerase II alpha defect in a patient with Bloom's syndrome. Hum. Mol. Genet. 6: 1427-1434
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 1427-1434
-
-
Foucault, F.1
Vaury, C.2
Barakat, A.3
Thibout, D.4
Planchon, P.5
Jaulin, C.6
-
49
-
-
0025579302
-
DNA repair and the molecular mechanisms of Bloom's syndrome
-
49 Sirover M. A., Vollberg T. M. and Seal G. (1990) DNA repair and the molecular mechanisms of Bloom's syndrome. Crit. Rev. Oncog. 2: 19-33
-
(1990)
Crit. Rev. Oncog.
, vol.2
, pp. 19-33
-
-
Sirover, M.A.1
Vollberg, T.M.2
Seal, G.3
-
50
-
-
0028785586
-
The Bloom's syndrome gene product is homologous to RecQ helicases
-
50 Ellis N. A., Groden J., Ye T. Z., Straughen J., Lennon D. J., Ciocci S. et al. (1995) The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 83: 655-666
-
(1995)
Cell
, vol.83
, pp. 655-666
-
-
Ellis, N.A.1
Groden, J.2
Ye, T.Z.3
Straughen, J.4
Lennon, D.J.5
Ciocci, S.6
-
51
-
-
0030686496
-
The Bloom's syndrome gene product is a 3′-5′ DNA helicase
-
51 Karow J. K., Chakraverty R. K. and Hickson I. D. (1997) The Bloom's syndrome gene product is a 3′-5′ DNA helicase. J. Biol. Chem. 272: 30611-30614
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30611-30614
-
-
Karow, J.K.1
Chakraverty, R.K.2
Hickson, I.D.3
-
52
-
-
0031576552
-
BLM (the causative gene of Bloom syndrome) protein translocation into the nucleus by a nuclear localization signal
-
52 Kaneko H., Orii K. O., Matsui E., Shimozawa N., Fukao T., MatsumotoT. et al. (1997) BLM (the causative gene of Bloom syndrome) protein translocation into the nucleus by a nuclear localization signal. Biochem. Biophys. Res. Commun. 240: 348-353
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.240
, pp. 348-353
-
-
Kaneko, H.1
Orii, K.O.2
Matsui, E.3
Shimozawa, N.4
Fukao, T.5
Matsumoto, T.6
-
53
-
-
0032547953
-
Point mutations causing Bloom's syndrome abolish ATPase and DNA helicase activities of the BLM protein
-
53 Bahr A., De Graeve F., Kedinger C. and Chatton B. (1998) Point mutations causing Bloom's syndrome abolish ATPase and DNA helicase activities of the BLM protein. Oncogene 17: 2565-2571
-
(1998)
Oncogene
, vol.17
, pp. 2565-2571
-
-
Bahr, A.1
De Graeve, F.2
Kedinger, C.3
Chatton, B.4
-
54
-
-
0032555220
-
Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: Implication for genomic instability in human diseases
-
54 Yamagata K., Kato J., Shimamoto A., Goto M., Furuichi Y. and Ikeda H. (1998) Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases. Proc. Natl. Acad. Sci. USA 95: 8733-8738
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8733-8738
-
-
Yamagata, K.1
Kato, J.2
Shimamoto, A.3
Goto, M.4
Furuichi, Y.5
Ikeda, H.6
-
55
-
-
0030820491
-
Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants
-
55 Sinclair D. A., Mills K. and Guarente L. (1997) Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. Science 277: 1313-1316
-
(1997)
Science
, vol.277
, pp. 1313-1316
-
-
Sinclair, D.A.1
Mills, K.2
Guarente, L.3
-
56
-
-
0029002965
-
Sgs1 : A eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation
-
56 Watt P. M., Louis E. J., Borts R. H. and Hickson I. D. (1995) Sgs1 : a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell 81: 253-260
-
(1995)
Cell
, vol.81
, pp. 253-260
-
-
Watt, P.M.1
Louis, E.J.2
Borts, R.H.3
Hickson, I.D.4
-
57
-
-
0028033989
-
The yeast type I topoisomerase Top3 interacts uith Sgs1, a DNA helicase homolog: A potential eukaryotic reverse gyrase
-
57 Gangloff S.. McDonald J. P., Bendixen C., Arthur L. and Rothstein R. (1994) The yeast type I topoisomerase Top3 interacts uith Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Mol. Cell. Biol. 14: 8391-8398
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 8391-8398
-
-
Gangloff, S.1
McDonald, J.P.2
Bendixen, C.3
Arthur, L.4
Rothstein, R.5
-
58
-
-
0030994386
-
rqh1 + , a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible s phase arrest
-
58 Stewart E., Chapman C. R., Al-Khodairy F., Carr A. M. and Enoch T. (1997) rqh1 + , a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest. EMBO J. 16: 2682-2692
-
(1997)
EMBO J.
, vol.16
, pp. 2682-2692
-
-
Stewart, E.1
Chapman, C.R.2
Al-Khodairy, F.3
Carr, A.M.4
Enoch, T.5
-
59
-
-
0031897062
-
Fission yeast rad12 + regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene
-
59 Davey S., Han C. S., Ramer S. A., Klassen J. C., Jacobson A., Eisenberger A. et al. (1998) Fission yeast rad12 + regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene. Mol. Cell. Biol. 18: 2721-2728
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2721-2728
-
-
Davey, S.1
Han, C.S.2
Ramer, S.A.3
Klassen, J.C.4
Jacobson, A.5
Eisenberger, A.6
-
60
-
-
0030888233
-
RecQ DNA helicase is a suppressor of illegitimate recombination in Escherichia coli
-
60 Hanada K., Ukita T., Kohno Y., Saito K., Kato J. and Ikeda H. (1997) RecQ DNA helicase is a suppressor of illegitimate recombination in Escherichia coli. Proc. Natl. Acad. Sci. USA 94: 3860-3865
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3860-3865
-
-
Hanada, K.1
Ukita, T.2
Kohno, Y.3
Saito, K.4
Kato, J.5
Ikeda, H.6
-
61
-
-
0028178787
-
The processing of recombination intermediates: Mechanistic insights from studies of bacterial proteins
-
61 West S. C. (1994) The processing of recombination intermediates: mechanistic insights from studies of bacterial proteins. Cell 76: 9-15
-
(1994)
Cell
, vol.76
, pp. 9-15
-
-
West, S.C.1
-
62
-
-
0027158626
-
RecQ DNA helicase of Escherichia coli: Characterization of the helix-unwinding activity with emphasis on the effect of single-stranded DNA-binding protein
-
62 Umezu K. and Nakayama H. (1993) RecQ DNA helicase of Escherichia coli: characterization of the helix-unwinding activity with emphasis on the effect of single-stranded DNA-binding protein. J. Mol. Biol. 230: 1145-1150
-
(1993)
J. Mol. Biol.
, vol.230
, pp. 1145-1150
-
-
Umezu, K.1
Nakayama, H.2
-
63
-
-
0032213939
-
Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene
-
63 Chester N., Kuo F., Kozak C., O'Hara C. D. and Leder P. (1998) Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene. Genes Dev. 12: 3382-3393
-
(1998)
Genes Dev.
, vol.12
, pp. 3382-3393
-
-
Chester, N.1
Kuo, F.2
Kozak, C.3
O'Hara, C.D.4
Leder, P.5
-
64
-
-
0019570997
-
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts
-
64 Warren S. T., Schultz R. A., Chang C. C., Wade M. H. and Trosko J. E. (1981) Elevated spontaneous mutation rate in Bloom syndrome fibroblasts. Proc. Natl. Acad. Sci. USA 78: 3133-3137
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 3133-3137
-
-
Warren, S.T.1
Schultz, R.A.2
Chang, C.C.3
Wade, M.H.4
Trosko, J.E.5
-
65
-
-
0013907774
-
Werner's syndrome: A review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process
-
65 Epstein C. J., Martin G. M., Schultz A. L. and Motulsky A. G. (1966) Werner's syndrome: a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine 45: 177-221
-
(1966)
Medicine
, vol.45
, pp. 177-221
-
-
Epstein, C.J.1
Martin, G.M.2
Schultz, A.L.3
Motulsky, A.G.4
-
66
-
-
0014816132
-
Replicative life-span of cultivated human cells: Effects of donor's age, tissue, and genotype
-
66 Martin G. M., Sprague C. A. and Epstein C. J. (1970) Replicative life-span of cultivated human cells: effects of donor's age, tissue, and genotype. Lab. Invest. 23: 86-92
-
(1970)
Lab. Invest.
, vol.23
, pp. 86-92
-
-
Martin, G.M.1
Sprague, C.A.2
Epstein, C.J.3
-
67
-
-
0019444282
-
Systematic growth studies, cocultivation, and cell hybridization studies of Werner syndrome cultured skin fibroblasts
-
67 Salk D., Bryan E., Au K., Hoehn H. and Martin G. M. (1981) Systematic growth studies, cocultivation, and cell hybridization studies of Werner syndrome cultured skin fibroblasts. Hum. Genet. 58: 310-316
-
(1981)
Hum. Genet.
, vol.58
, pp. 310-316
-
-
Salk, D.1
Bryan, E.2
Au, K.3
Hoehn, H.4
Martin, G.M.5
-
68
-
-
0020306698
-
Prolongation of S phase and whole cell cycle in Werner's syndrome fibroblasts
-
68 Takeuchi F., Hanaoka F., Goto M. and Yamada M. (1982) Prolongation of S phase and whole cell cycle in Werner's syndrome fibroblasts. Exp. Gerontol. 17: 473-480
-
(1982)
Exp. Gerontol.
, vol.17
, pp. 473-480
-
-
Takeuchi, F.1
Hanaoka, F.2
Goto, M.3
Yamada, M.4
-
69
-
-
0019979019
-
Altered frequency of initiation sites of DNA replication in Werner's syndrome cells
-
69 Takeuchi F., Hanaoka F., Goto M., Akaoka I., Hori T., Yamada M. et al. (1982) Altered frequency of initiation sites of DNA replication in Werner's syndrome cells. Hum. Genet. 60: 365-368
-
(1982)
Hum. Genet.
, vol.60
, pp. 365-368
-
-
Takeuchi, F.1
Hanaoka, F.2
Goto, M.3
Akaoka, I.4
Hori, T.5
Yamada, M.6
-
70
-
-
0020538765
-
Decrease in the average size of replicons in a Werner syndrome cell line by simian virus 40 infection
-
70 Hanaoka F., Takeuchi F., Matsumura T.,Goto M., Miyamoto T. and Yamada M. (1983) Decrease in the average size of replicons in a Werner syndrome cell line by simian virus 40 infection. Exp. Cell Res. 144: 463-467
-
(1983)
Exp. Cell Res.
, vol.144
, pp. 463-467
-
-
Hanaoka, F.1
Takeuchi, F.2
Matsumura, T.3
Goto, M.4
Miyamoto, T.5
Yamada, M.6
-
71
-
-
0020455613
-
Werner's syndrome: A review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations
-
71 Salk D. (1982) Werner's syndrome: a review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations. Hum. Genet. 62: 1-5
-
(1982)
Hum. Genet.
, vol.62
, pp. 1-5
-
-
Salk, D.1
-
72
-
-
0017668626
-
A retarded rate of DNA replication and normal level of DNA repair in Werner's syndrome fibroblasts in culture
-
72 Fujiwara Y., Higashikawa T. and Tatsumi M. (1977) A retarded rate of DNA replication and normal level of DNA repair in Werner's syndrome fibroblasts in culture. J. Cell. Physiol. 92: 365-374
-
(1977)
J. Cell. Physiol.
, vol.92
, pp. 365-374
-
-
Fujiwara, Y.1
Higashikawa, T.2
Tatsumi, M.3
-
73
-
-
0018195078
-
Normal level of unscheduled DNA synthesis in Werner's syndrome fibroblasts in culture
-
73 Higashikawa T. and Fujiwara Y. (1978) Normal level of unscheduled DNA synthesis in Werner's syndrome fibroblasts in culture. Exp. Cell Res. 113: 438-442
-
(1978)
Exp. Cell Res.
, vol.113
, pp. 438-442
-
-
Higashikawa, T.1
Fujiwara, Y.2
-
75
-
-
0029944713
-
DNA repair fine structure in Werner's syndrome cell lines
-
75 Webb D. K., Evans M. K. and Bohr V. A. (1996) DNA repair fine structure in Werner's syndrome cell lines. Exp. Cell Res. 224: 272-278
-
(1996)
Exp. Cell Res.
, vol.224
, pp. 272-278
-
-
Webb, D.K.1
Evans, M.K.2
Bohr, V.A.3
-
76
-
-
0030829431
-
Mismatch repair in extracts of Werner syndrome cell lines
-
76 Bennett S. E., Umar A.,Oshima J., Monnat R. J. Jr and Kunkel T. A. (1997) Mismatch repair in extracts of Werner syndrome cell lines. Cancer Res. 57: 2956-2960
-
(1997)
Cancer Res.
, vol.57
, pp. 2956-2960
-
-
Bennett, S.E.1
Umar, A.2
Oshima, J.3
Monnat R.J., Jr.4
Kunkel, T.A.5
-
77
-
-
0021997395
-
Elevated spontaneous mutation rate in SV40-transformed Werner syndrome fibroblast cell lines
-
77 Fukuchi K., Tanaka K., Nakura J., Kumahara Y., Uchida T. and Okada Y. (1985) Elevated spontaneous mutation rate in SV40-transformed Werner syndrome fibroblast cell lines. Somat. Cell Mol. Genet. 11: 303-308
-
(1985)
Somat. Cell Mol. Genet.
, vol.11
, pp. 303-308
-
-
Fukuchi, K.1
Tanaka, K.2
Nakura, J.3
Kumahara, Y.4
Uchida, T.5
Okada, Y.6
-
78
-
-
0024465870
-
Mutator phenotype of Werner syndrome is characterized by extensive deletions
-
78 Fukuchi K., Martin G. M. and Monnat R. J. Jr (1989) Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proc. Natl. Acad. Sci. USA 86: 5893-5897
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5893-5897
-
-
Fukuchi, K.1
Martin, G.M.2
Monnat R.J., Jr.3
-
79
-
-
0025169778
-
Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients
-
79 Fukuchi K., Tanaka K., Kumahara Y., Marumo K., Pride M. B., Martin G. M. et al. (1990) Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients. Hum. Genet. 84: 249-252
-
(1990)
Hum. Genet.
, vol.84
, pp. 249-252
-
-
Fukuchi, K.1
Tanaka, K.2
Kumahara, Y.3
Marumo, K.4
Pride, M.B.5
Martin, G.M.6
-
80
-
-
0025866760
-
Diverse gene sequences are overexpressed in Werner syndrome fibroblasts undergoing premature replicative senescence
-
80 Murano S., Thweatt R., Shmookler Reis R. J., Jones R. A., Moerman E. J. and Goldstein S. ( 1991 ) Diverse gene sequences are overexpressed in Werner syndrome fibroblasts undergoing premature replicative senescence. Mol. Cell. Biol. 11: 3905-3914
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 3905-3914
-
-
Murano, S.1
Thweatt, R.2
Shmookler Reis, R.J.3
Jones, R.A.4
Moerman, E.J.5
Goldstein, S.6
-
81
-
-
0029922445
-
Identification of gene sequences overexpressed in senescent and Werner syndrome human fibroblasts
-
81 Lecka-Czernik B., Moerman E. J., Jones R. A. and Goldstein S. (1996) Identification of gene sequences overexpressed in senescent and Werner syndrome human fibroblasts. Exp. Geromol. 31: 159-174
-
(1996)
Exp. Geromol.
, vol.31
, pp. 159-174
-
-
Lecka-Czernik, B.1
Moerman, E.J.2
Jones, R.A.3
Goldstein, S.4
-
82
-
-
0022858295
-
Diminished response of Werner's syndrome fibroblasts to growth factors PDGF and FGF
-
82 Bauer E. A., Silverman N., Busiek D. F., Kronberger A. and Deuel T. F. (1986) Diminished response of Werner's syndrome fibroblasts to growth factors PDGF and FGF. Science 234: 1240-1243
-
(1986)
Science
, vol.234
, pp. 1240-1243
-
-
Bauer, E.A.1
Silverman, N.2
Busiek, D.F.3
Kronberger, A.4
Deuel, T.F.5
-
83
-
-
0030751354
-
The Werner syndrome protein is a DNA helicase
-
83 Gray M. D., Shen J. C., Kamath-Loeb A. S., Blank A., Sopher B. L., Martin G. M. et al. (1997) The Werner syndrome protein is a DNA helicase. Nat. Genet. 17: 100-103
-
(1997)
Nat. Genet.
, vol.17
, pp. 100-103
-
-
Gray, M.D.1
Shen, J.C.2
Kamath-Loeb, A.S.3
Blank, A.4
Sopher, B.L.5
Martin, G.M.6
-
84
-
-
0031204917
-
Impaired nuclear localization of defective DNA helicases in Werner's syndrome
-
84 Matsumoto T., Shimamoto A., Goto M. and Furuichi Y. (1997) Impaired nuclear localization of defective DNA helicases in Werner's syndrome. Nat. Genet. 16: 335-336
-
(1997)
Nat. Genet.
, vol.16
, pp. 335-336
-
-
Matsumoto, T.1
Shimamoto, A.2
Goto, M.3
Furuichi, Y.4
-
85
-
-
0031459980
-
Extrachromosomal rDNA circles a cause of aging in yeast
-
85 Sinclair D. A. and Guarente L. (1997) Extrachromosomal rDNA circles a cause of aging in yeast. Cell 91: 1033-1042
-
(1997)
Cell
, vol.91
, pp. 1033-1042
-
-
Sinclair, D.A.1
Guarente, L.2
-
86
-
-
0032146147
-
Werner helicase is localized to transcriptionally active nucleoli of cycling cells
-
86 Gray M. D., Wang L., Youssoufian H., Martin G. M. and Oshima J. (1998) Werner helicase is localized to transcriptionally active nucleoli of cycling cells. Exp. Cell Res. 242: 487-494
-
(1998)
Exp. Cell Res.
, vol.242
, pp. 487-494
-
-
Gray, M.D.1
Wang, L.2
Youssoufian, H.3
Martin, G.M.4
Oshima, J.5
-
87
-
-
0031686571
-
The premature ageing syndrome protein, WRN, is a 3′→5′ exonuclease
-
87 Huang S., Li B., Gray M. D., Oshima J., Mian I. S. and Campisi J. (1998) The premature ageing syndrome protein, WRN, is a 3′→5′ exonuclease. Nat. Genet. 20: 114-116
-
(1998)
Nat. Genet.
, vol.20
, pp. 114-116
-
-
Huang, S.1
Li, B.2
Gray, M.D.3
Oshima, J.4
Mian, I.S.5
Campisi, J.6
-
88
-
-
0030915681
-
Positionally cloned human disease genes: Patterns of evolutionary conservation and functional motifs
-
88 Mushegian A. R., Bassett D. E. Jr, Boguski M. S., Bork P. and Koonin E. V. (1997) Positionally cloned human disease genes: patterns of evolutionary conservation and functional motifs. Proc. Natl. Acad. Sci. USA 94: 5831-5836
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5831-5836
-
-
Mushegian, A.R.1
Bassett D.E., Jr.2
Boguski, M.S.3
Bork, P.4
Koonin, E.V.5
-
89
-
-
0030836805
-
Comparative sequence analysis of ribonucleases HII, HI, II PH and D
-
89 Mian I. S. (1997) Comparative sequence analysis of ribonucleases HII, HI, II PH and D. Nucleic Acids Res. 25: 3187-3195
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3187-3195
-
-
Mian, I.S.1
-
90
-
-
0032573157
-
A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity
-
90 Lebel M. and Leder P. (1998) A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity. Proc. Natl. Acad. Sci. USA 95: 13097-13102
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13097-13102
-
-
Lebel, M.1
Leder, P.2
-
91
-
-
0001225459
-
Differential effects of cytotoxic drugs on mortal and immortalized B-lymphoblastoid cell lines from normal and Werner's syndrome patients
-
91 Okada M., Goto M., Furuichi Y. and Sugimoto M. (1998) Differential effects of cytotoxic drugs on mortal and immortalized B-lymphoblastoid cell lines from normal and Werner's syndrome patients. Biol. Pharm. Bull. 21: 235-239
-
(1998)
Biol. Pharm. Bull.
, vol.21
, pp. 235-239
-
-
Okada, M.1
Goto, M.2
Furuichi, Y.3
Sugimoto, M.4
-
92
-
-
0031848284
-
Replication focus-forming activity 1 and the Werner syndrome gene product
-
92 Yan H., Chen C. Y., Kobayashi R. and Newport J. (1998) Replication focus-forming activity 1 and the Werner syndrome gene product. Nat. Genet. 19: 375-378
-
(1998)
Nat. Genet.
, vol.19
, pp. 375-378
-
-
Yan, H.1
Chen, C.Y.2
Kobayashi, R.3
Newport, J.4
-
93
-
-
0019011091
-
Roles of nuclear and cytoplasmic environments in the retarded DNA synthesis in Werner syndrome cells
-
93 Tanaka K., Nakazawa T., Okada Y. and Kumahara Y. (1980) Roles of nuclear and cytoplasmic environments in the retarded DNA synthesis in Werner syndrome cells. Exp. Cell Res. 127: 185-190
-
(1980)
Exp. Cell Res.
, vol.127
, pp. 185-190
-
-
Tanaka, K.1
Nakazawa, T.2
Okada, Y.3
Kumahara, Y.4
-
94
-
-
0032534068
-
Failure to complement abnormal phenotypes of simian virus 40-transformed Werner syndrome cells by introduction of a normal human chromosome 8
-
94 Kodama S., Kashino G., Suzuki K., Takatsuji T., Okumura Y.,Oshimura M. et al. (1998) Failure to complement abnormal phenotypes of simian virus 40-transformed Werner syndrome cells by introduction of a normal human chromosome 8. Cancer Res. 58: 5188-5195
-
(1998)
Cancer Res.
, vol.58
, pp. 5188-5195
-
-
Kodama, S.1
Kashino, G.2
Suzuki, K.3
Takatsuji, T.4
Okumura, Y.5
Oshimura, M.6
-
95
-
-
0028939603
-
Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome)
-
95 Gibbons R. J., Picketts D. J., Villard L. and Higgs D. R. (1995) Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome). Cell 80: 837-845
-
(1995)
Cell
, vol.80
, pp. 837-845
-
-
Gibbons, R.J.1
Picketts, D.J.2
Villard, L.3
Higgs, D.R.4
-
96
-
-
0028467446
-
Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI SNF complex
-
96 Cote J., Quinn J., Workman J. L and Peterson C. L. (1994) Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI SNF complex. Science 265: 53-60
-
(1994)
Science
, vol.265
, pp. 53-60
-
-
Cote, J.1
Quinn, J.2
Workman, J.L.3
Peterson, C.L.4
-
97
-
-
0029827343
-
ATRX encodes a novel member of the SNF2 family of proteins: Mutations point to a common mechanism underlying the ATR-x syndrome
-
97 Picketts D. J., Higgs D. R., Bachoo S., Blake D. J., Quarrell O. W. and Gibbons R. J. (1996) ATRX encodes a novel member of the SNF2 family of proteins: mutations point to a common mechanism underlying the ATR-X syndrome. Hum. Mol. Genet. 5: 1899-1907
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1899-1907
-
-
Picketts, D.J.1
Higgs, D.R.2
Bachoo, S.3
Blake, D.J.4
Quarrell, O.W.5
Gibbons, R.J.6
-
98
-
-
0031922879
-
Specific interaction between the XNP, ATR-X gene product and the SET domain of the human EZH2 protein
-
98 Cardoso C., Timsit S., Villard L., Khrestchatisky M., Fontes M. and Colleaux L. (1998) Specific interaction between the XNP, ATR-X gene product and the SET domain of the human EZH2 protein. Hum. Mol. Genet. 7: 679-684
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 679-684
-
-
Cardoso, C.1
Timsit, S.2
Villard, L.3
Khrestchatisky, M.4
Fontes, M.5
Colleaux, L.6
-
99
-
-
0029013420
-
Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments
-
99 Craddock C. F., Vyas P., Sharpe J. A., Ayyub H., Wood W. G. and Higgs D. R. (1995) Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments. EMBO J. 14: 1718-1726
-
(1995)
EMBO J.
, vol.14
, pp. 1718-1726
-
-
Craddock, C.F.1
Vyas, P.2
Sharpe, J.A.3
Ayyub, H.4
Wood, W.G.5
Higgs, D.R.6
-
100
-
-
0029968719
-
The alpha-thalassemia/mental retardation syndromes
-
100 Gibbons R. J and Higgs D. R. (1996) The alpha-thalassemia/mental retardation syndromes. Medicine 75: 45-52
-
(1996)
Medicine
, vol.75
, pp. 45-52
-
-
Gibbons, R.J.1
Higgs, D.R.2
-
101
-
-
0032170558
-
The coding region of the Bloom syndrome BLM gene and of the CBL proto-oncogene is mutated in genetically unstable sporadic gastrointestinal tumors
-
101 Calin G., Herlea V., Barbanti-Brodano G. and Negrini M. (1998) The coding region of the Bloom syndrome BLM gene and of the CBL proto-oncogene is mutated in genetically unstable sporadic gastrointestinal tumors. Cancer Res. 58: 3777-3781
-
(1998)
Cancer Res.
, vol.58
, pp. 3777-3781
-
-
Calin, G.1
Herlea, V.2
Barbanti-Brodano, G.3
Negrini, M.4
-
102
-
-
17344379792
-
Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population
-
102 Ye L., Miki T., Nakura J., Oshima J., Kamino K., Rakugi H. et al. (1997) Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population. Am. J. Med. Genet. 68: 494-498
-
(1997)
Am. J. Med. Genet.
, vol.68
, pp. 494-498
-
-
Ye, L.1
Miki, T.2
Nakura, J.3
Oshima, J.4
Kamino, K.5
Rakugi, H.6
-
103
-
-
0031561143
-
Down-regulation of the defective transcripts of the Werner's syndrome gene in the cells of patients
-
103 Yamabe Y., Sugimoto M., Satoh M., Suzuki N., Sugawara M., Goto M. et al. (1997) Down-regulation of the defective transcripts of the Werner's syndrome gene in the cells of patients. Biochem. Biophys. Res. Commun. 236: 151-154
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.236
, pp. 151-154
-
-
Yamabe, Y.1
Sugimoto, M.2
Satoh, M.3
Suzuki, N.4
Sugawara, M.5
Goto, M.6
-
104
-
-
0030025660
-
Replicative senescence: An old lives' tale?
-
104 Campisi J. (1996) Replicative senescence: an old lives' tale? Cell 84: 497-500
-
(1996)
Cell
, vol.84
, pp. 497-500
-
-
Campisi, J.1
-
105
-
-
0029023626
-
Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved
-
105 Wang E. (1995) Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved. Cancer Res. 55: 2284-2292
-
(1995)
Cancer Res.
, vol.55
, pp. 2284-2292
-
-
Wang, E.1
-
106
-
-
0032481342
-
Downregulated expression of the signaling molecules Nck, c-Crk, Grb2/Ash, PI 3-kinase pI 10 alpha and WRN during fibroblast aging in vitro
-
106 Matuoka K. and Takenawa T. (1998) Downregulated expression of the signaling molecules Nck, c-Crk, Grb2/Ash, PI 3-kinase pI 10 alpha and WRN during fibroblast aging in vitro. Biochim. Biophys. Acta 1401: 211-215
-
(1998)
Biochim. Biophys. Acta
, vol.1401
, pp. 211-215
-
-
Matuoka, K.1
Takenawa, T.2
-
107
-
-
0032145990
-
Structure and function of the human Werner syndrome gene promoter: Evidence for transcriptional modulation
-
107 Wang L., Hunt K. E., Martin G. M. and Oshima J. (1998) Structure and function of the human Werner syndrome gene promoter: evidence for transcriptional modulation. Nucleic Acids Res. 26: 3480-3485
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 3480-3485
-
-
Wang, L.1
Hunt, K.E.2
Martin, G.M.3
Oshima, J.4
-
108
-
-
0032101153
-
Effect of age and apoptosis on the mouse homologue of the huWRN gene
-
108 Wu J., He J. and Mountz J. D. (1998) Effect of age and apoptosis on the mouse homologue of the huWRN gene. Mech. Ageing Dev. 103: 27-44
-
(1998)
Mech. Ageing Dev.
, vol.103
, pp. 27-44
-
-
Wu, J.1
He, J.2
Mountz, J.D.3
-
109
-
-
0032519426
-
Increased apoptosis of T cell subsets in aging humans: Altered expression of Fas (CD95), Fas ligand, Bcl-2, and Bax
-
109 Aggarwal S. and Gupta S. (1998) Increased apoptosis of T cell subsets in aging humans: altered expression of Fas (CD95), Fas ligand, Bcl-2, and Bax. J. Immunol. 160: 1627-1637
-
(1998)
J. Immunol.
, vol.160
, pp. 1627-1637
-
-
Aggarwal, S.1
Gupta, S.2
-
110
-
-
0029014623
-
Age-dependent reduction of Bcl-2 expression in peripheral T cells of lpr and gld mutant mice
-
110 Tamura A. and Yui K. (1995) Age-dependent reduction of Bcl-2 expression in peripheral T cells of lpr and gld mutant mice. J. Immunol. 155: 499-507
-
(1995)
J. Immunol.
, vol.155
, pp. 499-507
-
-
Tamura, A.1
Yui, K.2
-
111
-
-
0027295019
-
The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation
-
111 Laurent B. C., Treich I. and Carlson M. (1993) The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation. Genes Dev. 7: 583-591
-
(1993)
Genes Dev.
, vol.7
, pp. 583-591
-
-
Laurent, B.C.1
Treich, I.2
Carlson, M.3
-
112
-
-
0028989236
-
p53 modulation of TFIIH-associated nucleotidc excision repair activity
-
112 Wang X. W., Yeh H., Schaeffer L., Roy R., Moncollin V., Egly J. M. et al. (1995) p53 modulation of TFIIH-associated nucleotidc excision repair activity. Nat. Genet. 10: 188-195
-
(1995)
Nat. Genet.
, vol.10
, pp. 188-195
-
-
Wang, X.W.1
Yeh, H.2
Schaeffer, L.3
Roy, R.4
Moncollin, V.5
Egly, J.M.6
-
113
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
113 Bodnar A. G., Ouellette M., Frolkis M., Holt S. E., Chiu C. P., Morin G. B. et al. (1998) Extension of life-span by introduction of telomerase into normal human cells. Science 279: 349-352
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chiu, C.P.5
Morin, G.B.6
-
114
-
-
0029971241
-
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells
-
114 Schulz V. P., Zakian V. A., Ogburn C. E., McKay J., Jarzebowicz A. A., Edland S. D. et al. (1996) Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells. Hum. Genet. 97: 750-754
-
(1996)
Hum. Genet.
, vol.97
, pp. 750-754
-
-
Schulz, V.P.1
Zakian, V.A.2
Ogburn, C.E.3
McKay, J.4
Jarzebowicz, A.A.5
Edland, S.D.6
|