Fission yeast rad12+ regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene

Molecular and Cellular Biology

Volumn 18, Issue 5, 1998, Pages 2721-2728

  Davey, Scott ^a   Han, Christine S ^b   Ramer, Sarah A ^a   Klassen, Jennifer C ^a   Jacobson, Adam ^b   Eisenberger, Andrew ^b   Hopkins, Kevin M ^b   Lieberman, Howard B ^b   Freyer, Greg A ^b  

^a QUEEN S UNIVERSITY   (Canada)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BLOOM SYNDROME; CELL CYCLE; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; YEAST;

ESCHERICHIA COLI; SACCHAROMYCES CEREVISIAE;

EID: 0031897062     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.5.2721     Document Type: Article

References (37)

1. 2 checkpoint pathways in Schizosaccharomyces pombe. EMBO J. 11:1343-1350.
2. al-Khodairy, F., E. Fotou, K. S. Sheldrick, D. J. Griffiths, A. R. Lehmann, and A. M. Carr. 1994. Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast. Mol. Biol. Cell 5:147-160.
3. + controls the transition from mitotic division to meiosis in fission yeast. Curr. Genet. 10:297-311.
4. Bentley, N. J., D. A. Holtzman, G. Flaggs, K. S. Keegan, A. DeMaggio, J. C. Ford, M. Hoekstra, and A. M. Carr. 1996. The Schizosaccharomyces pombe rad3 checkpoint gene. EMBO J. 15:6641-6651.
5. Cimprich, K. A., R. B. Shin, C. T. Keith, and S. L. Schreiber. 1996. cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein. Proc. Natl. Acad. Sci. USA 93:2850-2855.
6. Darlington, G. J., R. Dutkowski, and W. T. Brown. 1981. Sister chromatid exchange frequencies in progeria and Werner syndrome patients. Am. J. Hum. Genet. 33:762-766.
7. Davey, S., M. L. Nass, J. V. Ferrer, K. Sidik, A. Eisenberger, D. L. Mitchell, and G. A. Freyer. 1997. The fission yeast UVDR DNA repair pathway is inducible. Nucleic Acids Res. 25:1002-1008.
8. Ellis, N. A., J. Groden, T. Z. Ye, J. Straughen, D. J. Lennon, S. Ciocci, M. Proytcheva, and J. German. 1995. The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 83:655-666.
9. Enoch, T., A. M. Carr, and P. Nurse. 1992. Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev. 6:2035-2046.
10. Freyer, G. A., S. Davey, J. V. Ferrer, A. M. Martin, D. Beach, and P. W. Doetsch. 1995. An alternative eukaryotic DNA excision repair pathway. Mol. Cell. Biol. 15:4572-4577.
11. Gangloff, S., J. P. McDonald, C. Bendixen, L. Arthur, and R. Rothstein. 1994. The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Mol. Cell. Biol. 14:8391-8398.
12. German, J. 1995. Bloom's syndrome. Dermatol. Clin. 13:7-18.
13. Gorbalenya, A. E., E. V. Koonin, A. P. Donchenko, and V. M. Blinov. 1989. Two related superfamilies of putative helicases involved in replication, recombination, repair and expression of DNA and RNA genomes. Nucleic Acids Res. 17:4713-4730.
14. Hartwell, L. 1992. Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 71:543-546.
15. Hawthorne, D. C., and U. Leupold. 1974. Suppressor mutations in yeast. Curr. Top. Microbiol. Immunol. 64:1-47.
16. Hoheisel, J. D., E. Maier, R. Mott, L. McCarthy, A. V. Grigoriev, L. C. Schalkwyk, D. Nizetic, F. Francis, and H. Lehrach. 1993. High resolution cosmid and P1 maps spanning the 14 Mb genome of the fission yeast S. pombe. Cell 73:109-120.
17. Leupold, U. 1970. Genetical methods for Schizosaccharomyces pombe. Methods Cell Physiol. 4:169-177.
18. Lieberman, H. B., K. M. Hopkins, M. Laverty, and H. M. Chu. 1992. Molecular cloning and analysis of Schizosaccharomyces pombe rad9, a gene involved in DNA repair and mutagenesis. Mol. Gen. Genet. 232:367-376.
19. + checkpoint control gene. Proc. Natl. Acad. Sci. USA 93:13890-13895.
20. Lu, J., J. R. Mullen, S. J. Brill, S. Kleff, A. M. Romeo, and R. Sternglanz. 1996. Human homologues of yeast helicase. Nature 383:678-679.
21. Lydall, D., and T. Weinert. 1995. Yeast checkpoint genes in DNA damage processing: implications for repair and arrest. Science 270:1488-1491.
22. Mizukami, T., W. I. Chang, I. Garkavtsev, N. Kaplan, D. Lombardi, T. Matsumoto, O. Niwa, A. Kounosu, M. Yanagida, T. G. Marr, and D. Beach. 1993. A 13 kb resolution cosmid map of the 14 Mb fission yeast genome by nonrandom sequence-tagged site mapping. Cell 73:121-132.
23. Murray, J. M., H. D. Lindsay, C. A. Munday, and A. M. Carr. 1997. Role of Schizosaccharomyces pombe RecQ homolog, recombination, and checkpoint genes in UV damage tolerance. Mol. Cell. Biol. 17:6868-6875.
24. Nasim, A., and B. P. Smith. 1975. Genetic control of radiation sensitivity in Schizosaccharomyces pombe. Genetics 79:573-582.
25. Rosen, K. M., E. D. Lamperti, and L. Villa-Komaroff. 1990. Optimizing the Northern blot procedure. BioTechniques 8:398-402.
26. Rothstein, R., and S. Gangloff. 1996. Hyper-recombination and Bloom's syndrome: microbes again provide clues about cancer. Genome Res. 5:258-262.
27. Rowley, R., S. Subramani, and P. G. Young. 1992. Checkpoint controls in Schizosaccharomyces pombe: rad1. EMBO J. 11:1335-1342.
28. Salk, D., E. Bryant, K. Au, H. Hoehn, and G. M. Martin. 1981. Systematic growth studies, cocultivation, and cell hybridization studies of Werner syndrome cultured skin fibroblasts. Hum. Genet. 58:310-316.
29. Sinclair, D. A., and L. Guarente. 1997. Extrachromosomal rDNA circles - a cause of aging in yeast. Cell 91:1033-1042.
30. Sinclair, D. A., K. Mills, and L. Guarente. 1997. Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. Science 277:1313-1316.
31. Smith, M. L., and A. J. Fornace, Jr. 1995. Genomic instability and the role of p53 mutations in cancer cells. Curr. Opin. Oncol. 7:69-75.
32. +, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest. EMBO J. 16:2682-2692.
33. Tlsty, T. D., A. Briot, A. Gualberto, I. Hall, S. Hess, M. Hixon, D. Kuppuswamy, S. Romanov, M. Sage, and A. White. 1995. Genomic instability and cancer. Mutat. Res. 337:1-7.
34. Umezu, K., K. Nakayama, and H. Nakayama. 1990. Escherichia coli RecQ protein is a DNA helicase. Proc. Natl. Acad. Sci. USA 87:5363-5367.
35. Watt, P. M., I. D. Hickson, R. H. Borts, and E. J. Louis. 1996. SGS1, a homologue of the Bloom's and Werner's syndrome genes, is required for maintenance of genome stability in Saccharomyces cerevisiae. Genetics 144: 935-945.
36. Watt, P. M., E. J. Louis, R. H. Borts, and I. D. Hickson. 1995. Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell 81:253-260.
37. Yu, C. E., J. Oshima, Y. H. Fu, E. M. Wijsman, F. Hisama, R. Alisch, S. Matthews, J. Nakura, T. Miki, S. Ouais, G. M. Martin, J. Mulligan, and G. D. Schellenberg. 1996. Positional cloning of the Werner's syndrome gene. Science 272:258-262.