-
1
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
-
Ionov, Y., Peinado, M. A., Malkhosyan, S., Shibata, D., and Perucho, M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature (Lond.), 363: 558-561, 1993.
-
(1993)
Nature (Lond.)
, vol.363
, pp. 558-561
-
-
Ionov, Y.1
Peinado, M.A.2
Malkhosyan, S.3
Shibata, D.4
Perucho, M.5
-
2
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler, K. W., and Vogelstein, B. Lessons from hereditary colorectal cancer. Cell, 87: 159-170, 1996.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
3
-
-
0028029122
-
Microsatellite instability occurs frequently in human gastric carcinoma
-
Rhyu, M-G., Park, W-S., and Meltzer, S. J. Microsatellite instability occurs frequently in human gastric carcinoma. Oncogene, 9: 29-32, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 29-32
-
-
Rhyu, M.-G.1
Park, W.-S.2
Meltzer, S.J.3
-
4
-
-
0028785603
-
Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer
-
Parsons, R., Myeroff, L. L., Liu, B., Willson, J. K. V., Markowitz, S. D., Kinzler, K. W., and Vogelstein, B. Microsatellite instability and mutations of the transforming growth factor β type II receptor gene in colorectal cancer. Cancer Res., 55: 5548-5550, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 5548-5550
-
-
Parsons, R.1
Myeroff, L.L.2
Liu, B.3
Willson, J.K.V.4
Markowitz, S.D.5
Kinzler, K.W.6
Vogelstein, B.7
-
5
-
-
16144368515
-
Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumors
-
Souza, R. F., Appel, R., Yin, J., Wang, S., Smolinski, K. N., Abraham, J. M., Zou, T-T., Shi, Y-Q., Lei, J., Cottrell, J., Cymes, K., Biden, K., Simms, L., Leggett, B., Lynch, P. M., Frazier, M., Powell, S. M., Harpaz, N., Sugimura, H., Young, J., and Meltzer, S. J. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumors. Nat. Genet., 14: 255-257, 1996.
-
(1996)
Nat. Genet.
, vol.14
, pp. 255-257
-
-
Souza, R.F.1
Appel, R.2
Yin, J.3
Wang, S.4
Smolinski, K.N.5
Abraham, J.M.6
Zou, T.-T.7
Shi, Y.-Q.8
Lei, J.9
Cottrell, J.10
Cymes, K.11
Biden, K.12
Simms, L.13
Leggett, B.14
Lynch, P.M.15
Frazier, M.16
Powell, S.M.17
Harpaz, N.18
Sugimura, H.19
Young, J.20
Meltzer, S.J.21
more..
-
6
-
-
0031018674
-
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
-
Washington DC
-
Rampino, N., Yamamoto, H., Ionov, Y., Li, Y., Saway, H., Reed, J. C., and Perucho, M. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science (Washington DC), 275: 967-969, 1997.
-
(1997)
Science
, vol.275
, pp. 967-969
-
-
Rampino, N.1
Yamamoto, H.2
Ionov, Y.3
Li, Y.4
Saway, H.5
Reed, J.C.6
Perucho, M.7
-
7
-
-
0029741089
-
Frameshift mutator mutations
-
Malkhosyan, S., Rampino, N., Yamamoto, H., and Perucho, M. Frameshift mutator mutations. Nature (Lond.), 382: 499-500, 1996.
-
(1996)
Nature (Lond.)
, vol.382
, pp. 499-500
-
-
Malkhosyan, S.1
Rampino, N.2
Yamamoto, H.3
Perucho, M.4
-
8
-
-
14444280359
-
Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors
-
Souza, R. F., Yin, J., Smolinski, K. N., Zou, T. T., Wang, S., Shi, Y. Q., Rhyu, M-G., Cottrell, J., Abraham, J. M., Biden, K., Simms, L., Leggett, B., Bova, G. S., Frank, T., Powell, S. M., Sugimura, H., Young, J., Harpaz, N., Shimizu, K., Matsubara, N., and Meltzer, S. J. Frequent mutation of the E2F-4 cell cycle gene in primary human gastrointestinal tumors. Cancer Res., 57: 2350-2353, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 2350-2353
-
-
Souza, R.F.1
Yin, J.2
Smolinski, K.N.3
Zou, T.T.4
Wang, S.5
Shi, Y.Q.6
Rhyu, M.-G.7
Cottrell, J.8
Abraham, J.M.9
Biden, K.10
Simms, L.11
Leggett, B.12
Bova, G.S.13
Frank, T.14
Powell, S.M.15
Sugimura, H.16
Young, J.17
Harpaz, N.18
Shimizu, K.19
Matsubara, N.20
Meltzer, S.J.21
more..
-
9
-
-
0028859671
-
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
-
Liu, B., Nicolaides, N. C., Markowitz, S., Willson, J. K., Parsons, R. E., Jen, J., Papadopolous, N., Peltomaki, P., de la Chapelle, A., Hamilton, S. R., Kinzler, K. W., and Vogelstein, B. Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nat. Genet., 9: 48-55, 1995.
-
(1995)
Nat. Genet.
, vol.9
, pp. 48-55
-
-
Liu, B.1
Nicolaides, N.C.2
Markowitz, S.3
Willson, J.K.4
Parsons, R.E.5
Jen, J.6
Papadopolous, N.7
Peltomaki, P.8
De La Chapelle, A.9
Hamilton, S.R.10
Kinzler, K.W.11
Vogelstein, B.12
-
10
-
-
0004136246
-
-
Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
-
Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
-
(1989)
Molecular Cloning: A Laboratory Manual
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
11
-
-
0029012254
-
Definition and refinement of chromosome 11 regions of loss of heterozygosity in breast cancer: Identification of a new region at 11q23.3
-
Negrini, M., Rasio, D., Hampton, G. M., Sabbioni, S., Rattan, S., Carter, S. L., Rosenberg, A. L., Schwartz, G. F., Shiloh, Y., Cavenee, W. K., and Croce, C. M. Definition and refinement of chromosome 11 regions of loss of heterozygosity in breast cancer: identification of a new region at 11q23.3. Cancer Res., 55: 3003-3007, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 3003-3007
-
-
Negrini, M.1
Rasio, D.2
Hampton, G.M.3
Sabbioni, S.4
Rattan, S.5
Carter, S.L.6
Rosenberg, A.L.7
Schwartz, G.F.8
Shiloh, Y.9
Cavenee, W.K.10
Croce, C.M.11
-
12
-
-
12644274663
-
Alternative genetic pathways in colorectal carcinogenesis
-
Olschwang, S., Hamelin, R., Laurent-Puig, P., Thuille, B., Rycke, Y. D., Li, Y-J., Muzeau, F., Girodet, J., Salmon, R-J., and Thomas, G. Alternative genetic pathways in colorectal carcinogenesis. Proc. Natl. Acad. Sci. USA, 94: 12122-12127, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 12122-12127
-
-
Olschwang, S.1
Hamelin, R.2
Laurent-Puig, P.3
Thuille, B.4
Rycke, Y.D.5
Li, Y.-J.6
Muzeau, F.7
Girodet, J.8
Salmon, R.-J.9
Thomas, G.10
-
13
-
-
0027136828
-
Genomic instability in colorectal cancer: Relationship to clinicopathological variables and family history
-
Lothe, R. A., Peltomaki, P., Meling, G. I., Aaltonen, L. A., Nystrom-Lahti, M., Pylkkanen, L., Heimdal, K., Andersen, T. I., Moller, P., Rognum, T. O., Fossa, S. D., Haldorsen, T., Langmark, F., Brogger, A., de la Chapelle, A., and Borresen, A-L. Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history. Cancer Res., 53: 5849-5852, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 5849-5852
-
-
Lothe, R.A.1
Peltomaki, P.2
Meling, G.I.3
Aaltonen, L.A.4
Nystrom-Lahti, M.5
Pylkkanen, L.6
Heimdal, K.7
Andersen, T.I.8
Moller, P.9
Rognum, T.O.10
Fossa, S.D.11
Haldorsen, T.12
Langmark, F.13
Brogger, A.14
De La Chapelle, A.15
Borresen, A.-L.16
-
14
-
-
0030061373
-
Microsatellite instability at multiple loci in gastric carcinoma: Clinicopathologic implications and prognosis
-
Santos, N. R. D., Seruca, R., Constancia, M., Seixas, M., and Sobrinho-Simoes, M. Microsatellite instability at multiple loci in gastric carcinoma: clinicopathologic implications and prognosis. Gastroenterology, 110: 38-44, 1996.
-
(1996)
Gastroenterology
, vol.110
, pp. 38-44
-
-
Santos, N.R.D.1
Seruca, R.2
Constancia, M.3
Seixas, M.4
Sobrinho-Simoes, M.5
-
15
-
-
8544223526
-
Apparent protection from instability of repeat sequences in cancer-related genes in replication error-positive gastrointestinal cancers
-
Simms, L. A., Zou, T-T., Young, J., Shi, Y-Q., Lei, J., Appel, R., Rhyu, M-G., Sugimura, H., Chenevix-Trench, G., Souza, R. F., Meltzer, S. J., and Leggett, B. A. Apparent protection from instability of repeat sequences in cancer-related genes in replication error-positive gastrointestinal cancers. Oncogene, 14: 2613-2618, 1997.
-
(1997)
Oncogene
, vol.14
, pp. 2613-2618
-
-
Simms, L.A.1
Zou, T.-T.2
Young, J.3
Shi, Y.-Q.4
Lei, J.5
Appel, R.6
Rhyu, M.-G.7
Sugimura, H.8
Chenevix-Trench, G.9
Souza, R.F.10
Meltzer, S.J.11
Leggett, B.A.12
-
16
-
-
0028785586
-
The Bloom's syndrome gene product is homologous to RecQ helicases
-
Ellis, N. A., Groden, J., Ye, T-Z., Straughen, J., Lennon, D. J., Ciocci, S., Proytcheva, M., and German, J. The Bloom's syndrome gene product is homologous to RecQ helicases. Cell, 83: 655-666, 1995.
-
(1995)
Cell
, vol.83
, pp. 655-666
-
-
Ellis, N.A.1
Groden, J.2
Ye, T.-Z.3
Straughen, J.4
Lennon, D.J.5
Ciocci, S.6
Proytcheva, M.7
German, J.8
-
17
-
-
0030686496
-
The Bloom's syndrome gene product is a 3′-5′ DNa helicase
-
Karow, J. K., Chakraverty, R. K., and Hickson, I. D. The Bloom's syndrome gene product is a 3′-5′ DNA helicase. J. Biol. Chem., 272: 30611-30614, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30611-30614
-
-
Karow, J.K.1
Chakraverty, R.K.2
Hickson, I.D.3
-
18
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Washington DC
-
Yu, C-E., Oshima, J., Fu, Y-H., Wijsman, E. M., Hisama, F., Alisch, R., Matthews, S., Nakura, J., Miki, T., Ouais, S., Martin, G. M., Mulligan, J., and Schellenberg, G. D. Positional cloning of the Werner's syndrome gene. Science (Washington DC), 272: 258-262, 1996.
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.-E.1
Oshima, J.2
Fu, Y.-H.3
Wijsman, E.M.4
Hisama, F.5
Alisch, R.6
Matthews, S.7
Nakura, J.8
Miki, T.9
Ouais, S.10
Martin, G.M.11
Mulligan, J.12
Schellenberg, G.D.13
-
19
-
-
0027942415
-
Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNa helicase RecQ
-
Puranam, K. L., and Blackshear, P. J. Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ. J. Biol. Chem., 269: 29838-29845, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 29838-29845
-
-
Puranam, K.L.1
Blackshear, P.J.2
-
20
-
-
0031004175
-
Genetic instability in colorectal cancers
-
Lengauer, C., Kinzler, K. W., and Vogelstein, B. Genetic instability in colorectal cancers. Nature (Lond.), 386: 623-627, 1997.
-
(1997)
Nature (Lond.)
, vol.386
, pp. 623-627
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
21
-
-
0032546360
-
Mutations of mitotic checkpoint genes in human cancers
-
Cahill, D. P., Lengauer, C., Yu, J., Riggins, G. J., Willson, J. K. V., Markowitz, S. D., Kinzler, K. W., and Vogelstein, B. Mutations of mitotic checkpoint genes in human cancers. Nature (Lond.), 392: 300-303, 1998.
-
(1998)
Nature (Lond.)
, vol.392
, pp. 300-303
-
-
Cahill, D.P.1
Lengauer, C.2
Yu, J.3
Riggins, G.J.4
Willson, J.K.V.5
Markowitz, S.D.6
Kinzler, K.W.7
Vogelstein, B.8
-
22
-
-
0031897062
-
+ regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene
-
+ regulates cell cycle checkpoint control and is homologous to the Bloom's syndrome disease gene. Mol. Cell. Biol., 18: 2721-2728, 1998.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2721-2728
-
-
Davey, S.1
Han, C.S.2
Ramer, S.A.3
Klassen, J.C.4
Jacobson, A.5
Eisenberger, A.6
Hopkins, K.M.7
Lieberman, H.B.8
Freyer, G.A.9
-
23
-
-
0030994386
-
+ , a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest
-
+ , a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest. EMBO J., 16: 2682-2692, 1997.
-
(1997)
EMBO J.
, vol.16
, pp. 2682-2692
-
-
Stewart, E.1
Chapman, C.R.2
Al-Khodairy, F.3
Carr, A.M.4
Enoch, T.5
-
24
-
-
0027331383
-
Bloom syndrome: A mendelian prototype of somatic mutational disease
-
German, J. Bloom syndrome: a mendelian prototype of somatic mutational disease. Medicine, 72: 393-406, 1993.
-
(1993)
Medicine
, vol.72
, pp. 393-406
-
-
German, J.1
-
25
-
-
3142544243
-
Evidence for increased in vivo mutation and somatic recombination in Bloom's syndrome
-
Langlois, R. G., Bigbee, W. L., Jensen, R. H., and German, J. Evidence for increased in vivo mutation and somatic recombination in Bloom's syndrome. Proc. Natl. Acad. Sci. USA, 86: 670-674, 1989.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 670-674
-
-
Langlois, R.G.1
Bigbee, W.L.2
Jensen, R.H.3
German, J.4
-
26
-
-
0027051362
-
Bloom's syndrome XVIII. Hypermutability at a tandem-repeat locus
-
Groden, J., and German, J. Bloom's syndrome XVIII. Hypermutability at a tandem-repeat locus. Hum. Genet., 90: 360-367, 1992.
-
(1992)
Hum. Genet.
, vol.90
, pp. 360-367
-
-
Groden, J.1
German, J.2
-
27
-
-
0029124883
-
Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl
-
Washington DC
-
Yoon, C. H., Lee, J., Jongeward, G. D., and Sternberg, P. W. Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl. Science (Washington DC), 269: 1102-1105, 1995.
-
(1995)
Science
, vol.269
, pp. 1102-1105
-
-
Yoon, C.H.1
Lee, J.2
Jongeward, G.D.3
Sternberg, P.W.4
-
28
-
-
0030889218
-
The product of the proto-oncogene c-cbl: A negative regulator of the Syk tyrosine kinase
-
Washington DC
-
Ota, Y., and Samelson, L. E. The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase. Science (Washington DC), 276: 418-420, 1997.
-
(1997)
Science
, vol.276
, pp. 418-420
-
-
Ota, Y.1
Samelson, L.E.2
-
29
-
-
12044256844
-
Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene
-
Andoniou, C. E., Thien, C. B. F., and Langdon, W. Y. Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene. EMBO J., 13: 4515-4523, 1994.
-
(1994)
EMBO J.
, vol.13
, pp. 4515-4523
-
-
Andoniou, C.E.1
Thien, C.B.F.2
Langdon, W.Y.3
-
30
-
-
0026525827
-
A rearrangement of the c-cbl proto-oncogene in HUT78 T-lymphoma cells results in a truncated protein
-
Blake, T. J., and Langdon, W. Y. A rearrangement of the c-cbl proto-oncogene in HUT78 T-lymphoma cells results in a truncated protein. Oncogene, 7: 757-762, 1992.
-
(1992)
Oncogene
, vol.7
, pp. 757-762
-
-
Blake, T.J.1
Langdon, W.Y.2
-
31
-
-
0030585383
-
Detection of HOXA1 expression in human breast cancer
-
Chariot, A., and Castronovo, V. Detection of HOXA1 expression in human breast cancer. Biochem. Biophys. Res. Commun., 222: 292-297, 1996.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.222
, pp. 292-297
-
-
Chariot, A.1
Castronovo, V.2
-
32
-
-
0029046887
-
Structure and function of the HOXA1 human homeobox gene cDNA
-
Amst.
-
Hong, Y. S., Kim, S. Y., Bhattacharya, A., Pratt, D. R., Hong, W. K., and Tainsky, M. A. Structure and function of the HOXA1 human homeobox gene cDNA. Gene (Amst.), 159: 209-214, 1995.
-
(1995)
Gene
, vol.159
, pp. 209-214
-
-
Hong, Y.S.1
Kim, S.Y.2
Bhattacharya, A.3
Pratt, D.R.4
Hong, W.K.5
Tainsky, M.A.6
|