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Volumn 14, Issue 1, 2000, Pages 23-42

The inhibitory effects of transforming growth factor-beta-1 (TGF-β1) in autoimmune diseases

Author keywords

CTLA 4; Regulatory T cell; Th3; Tolerance; Transforming growth factor beta

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0033953109     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1006/jaut.1999.0339     Document Type: Review
Times cited : (252)

References (235)
  • 1
    • 0000175795 scopus 로고    scopus 로고
    • Transforming growth factor-β And its receptors
    • A. Thompson. New York: Academic Press
    • Derynck R., Choy L. Transforming growth factor-β and its receptors. Thompson A. The cytokine handbook. 1998;593-638 Academic Press, New York.
    • (1998) The Cytokine Handbook , pp. 593-638
    • Derynck, R.1    Choy, L.2
  • 3
    • 0031944290 scopus 로고    scopus 로고
    • Regulation of immune responses by TGF-β
    • Letterio J.J., Roberts A.B. Regulation of immune responses by TGF-β Ann. Rev. Immunol. 16:1998;137-161.
    • (1998) Ann. Rev. Immunol. , vol.16 , pp. 137-161
    • Letterio, J.J.1    Roberts, A.B.2
  • 5
    • 0032430075 scopus 로고    scopus 로고
    • Signal transduction by transforming growth factor-beta: A cooperative paradigm with extensive negative regulation
    • Engel M.E., Datta P.K., Moses H.L. Signal transduction by transforming growth factor-beta: a cooperative paradigm with extensive negative regulation. J. Cell. Biochem. 30-31:1998;111-122.
    • (1998) J. Cell. Biochem. , vol.3031 , pp. 111-122
    • Engel, M.E.1    Datta, P.K.2    Moses, H.L.3
  • 6
    • 0000116653 scopus 로고
    • The transforming growth factor-betas
    • M. Sporn, & A. Roberts. New York: Springer Verlag
    • Roberts A.B., Sporn M.B. The transforming growth factor-betas. Sporn M., Roberts A. Peptide growth factors and their receptors. 1990;419-472 Springer Verlag, New York.
    • (1990) Peptide Growth Factors and Their Receptors , pp. 419-472
    • Roberts, A.B.1    Sporn, M.B.2
  • 7
    • 0026053972 scopus 로고
    • Differential expression of TGF-β1, β2 and β3 genes during mouse embryogenesis
    • Schmid P., Cox D., Bilbe G., Rainer M., McMaster G.K. Differential expression of TGF-β1, β2 and β3 genes during mouse embryogenesis. Development. 11:1991;117-130.
    • (1991) Development , vol.11 , pp. 117-130
    • Schmid, P.1    Cox, D.2    Bilbe, G.3    Rainer, M.4    McMaster, G.K.5
  • 8
    • 0026772232 scopus 로고
    • Differential expression of the TGF-β isoforms in embryogenesis suggests specific roles in developing and adult tissues
    • Roberts A.B., Sporn M.B. Differential expression of the TGF-β isoforms in embryogenesis suggests specific roles in developing and adult tissues. Mol. Report. Dev. 32:1992;91-98.
    • (1992) Mol. Report. Dev. , vol.32 , pp. 91-98
    • Roberts, A.B.1    Sporn, M.B.2
  • 11
    • 0024389620 scopus 로고
    • Complex regulation of transforming growth factor β1, β2 and β3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors β1 and β2
    • Bascom C., Wolfshohl J., Coffey R. Complex regulation of transforming growth factor β1, β2 and β3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors β1 and β2. Mol. Cell. Biol. 9:1989;5508-5515.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 5508-5515
    • Bascom, C.1    Wolfshohl, J.2    Coffey, R.3
  • 13
    • 0023886444 scopus 로고
    • Latent transforming growth factor-β From human platelets. A high molecular weight complex containing precursor sequences
    • Wakefield L.M., Smith D.M., Flanders K.C., Sporn M.B. Latent transforming growth factor-β from human platelets. A high molecular weight complex containing precursor sequences. J. Biol. Chem. 263:1988;7646-7654.
    • (1988) J. Biol. Chem. , vol.263 , pp. 7646-7654
    • Wakefield, L.M.1    Smith, D.M.2    Flanders, K.C.3    Sporn, M.B.4
  • 14
    • 0028180315 scopus 로고
    • The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
    • Kingsley D.M. The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev. 8:1994;133-146.
    • (1994) Genes Dev. , vol.8 , pp. 133-146
    • Kingsley, D.M.1
  • 15
    • 0024358460 scopus 로고
    • Transforming growth factor-β (TGF-β) receptor proteoglycan. Cell surface expression and ligand binding in the absence of glycosaminoglycan chains
    • Cheifetz S., Massagué J. Transforming growth factor-β (TGF-β) receptor proteoglycan. Cell surface expression and ligand binding in the absence of glycosaminoglycan chains. J. Biol. Chem. 264:1989;12025-12028.
    • (1989) J. Biol. Chem. , vol.264 , pp. 12025-12028
    • Cheifetz, S.1    Massagué, J.2
  • 16
    • 0026785290 scopus 로고
    • Inhibition of growth by transforming growth factor-β following fusion of two nonresponsive human carcinoma cell lines
    • Geiser A.G., Burmester J.K., Webbink R., Roberts A.B., Sporn M.B. Inhibition of growth by transforming growth factor-β following fusion of two nonresponsive human carcinoma cell lines. J. Biol. Chem. 267:1992;2588-2593.
    • (1992) J. Biol. Chem. , vol.267 , pp. 2588-2593
    • Geiser, A.G.1    Burmester, J.K.2    Webbink, R.3    Roberts, A.B.4    Sporn, M.B.5
  • 17
    • 0027250810 scopus 로고
    • Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-β activities
    • Chen R.H., Ebner R., Derynck R. Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-β activities. Science. 260:1993;1335-1338.
    • (1993) Science. , vol.260 , pp. 1335-1338
    • Chen, R.H.1    Ebner, R.2    Derynck, R.3
  • 18
    • 0027219671 scopus 로고
    • Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor
    • Ebner R., Chen R.H., Shum L., Lawler S., Zionchek T.F., Lee A., Lopez A.R., Derynck R. Cloning of a type I TGF-β receptor and its effect on TGF-β binding to the type II receptor. Science. 260:1993;1344-1348.
    • (1993) Science , vol.260 , pp. 1344-1348
    • Ebner, R.1    Chen, R.H.2    Shum, L.3    Lawler, S.4    Zionchek, T.F.5    Lee, A.6    Lopez, A.R.7    Derynck, R.8
  • 21
    • 0026778310 scopus 로고
    • Transforming growth factor-beta in disease: The dark side of tissue repair
    • Border W.A., Ruoslahti E. Transforming growth factor-beta in disease: The dark side of tissue repair. J. Clin. Invest. 90:1992;1-7.
    • (1992) J. Clin. Invest. , vol.90 , pp. 1-7
    • Border, W.A.1    Ruoslahti, E.2
  • 22
    • 0025353729 scopus 로고
    • Negative regulation of transforming growth factor-β By the proteoglycan decorin
    • Yamaguchi Y., Mann D.M., Ruoslahti E. Negative regulation of transforming growth factor-β by the proteoglycan decorin. Nature. 346:1990;281-284.
    • (1990) Nature , vol.346 , pp. 281-284
    • Yamaguchi, Y.1    Mann, D.M.2    Ruoslahti, E.3
  • 23
    • 0028057726 scopus 로고
    • Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-β
    • Yamashita H., Ichijo H., Grimsby S., Moren A., Ten Dijke P., Miyazono K. Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-β J. Biol. Chem. 269:1994;13231-13237.
    • (1994) J. Biol. Chem. , vol.269 , pp. 13231-13237
    • Yamashita, H.1    Ichijo, H.2    Grimsby, S.3    Moren, A.4    Ten Dijke, P.5    Miyazono, K.6
  • 24
    • 0023193194 scopus 로고
    • Latent transforming growth factor-β In serum. A specific complex with α-macroglobulin
    • O'Connor-McCourt M.D., Wakefield L.M. Latent transforming growth factor-β in serum. A specific complex with α-macroglobulin. J. Biol. Chem. 262:1987;14090-14099.
    • (1987) J. Biol. Chem. , vol.262 , pp. 14090-14099
    • O'Connor-Mccourt, M.D.1    Wakefield, L.M.2
  • 27
    • 0023240580 scopus 로고
    • Fibronectin-associated transforming growth factor
    • Fava R., McClure D.B. Fibronectin-associated transforming growth factor. J. Cell. Physiol. 131:1987;184-189.
    • (1987) J. Cell. Physiol. , vol.131 , pp. 184-189
    • Fava, R.1    McClure, D.B.2
  • 28
    • 0026082034 scopus 로고
    • Transforming growth factor β type 1 binds to collagen IV of basement membrane matrix: Implications for development
    • Paralkar V.M., Vukicevic S., Reddi A.H. Transforming growth factor β type 1 binds to collagen IV of basement membrane matrix: implications for development. Dev. Biol. 143:1991;303-308.
    • (1991) Dev. Biol. , vol.143 , pp. 303-308
    • Paralkar, V.M.1    Vukicevic, S.2    Reddi, A.H.3
  • 29
    • 0028020587 scopus 로고
    • Spontaneous elaboration of transforming growth factor beta suppresses host defense against bacterial infection in autoimmune MRL/lpr mice
    • Lowrance J.H., O'Sullivan F.X., Caver T.E., Waegell W., Gresham H.D. Spontaneous elaboration of transforming growth factor beta suppresses host defense against bacterial infection in autoimmune MRL/lpr mice. J. Exp. Med. 180:1994;1693-1703.
    • (1994) J. Exp. Med. , vol.180 , pp. 1693-1703
    • Lowrance, J.H.1    O'Sullivan, F.X.2    Caver, T.E.3    Waegell, W.4    Gresham, H.D.5
  • 30
    • 0028927204 scopus 로고
    • Autoantibodies produced spontaneously by young lpr mice carry transforming growth factor beta and suppress cytotoxic T lymphocyte responses
    • Rowley D.A., Becken E.T., Stach R.M. Autoantibodies produced spontaneously by young lpr mice carry transforming growth factor beta and suppress cytotoxic T lymphocyte responses. J. Exp. Med. 181:1995;1875-1880.
    • (1995) J. Exp. Med. , vol.181 , pp. 1875-1880
    • Rowley, D.A.1    Becken, E.T.2    Stach, R.M.3
  • 31
    • 0029808482 scopus 로고    scopus 로고
    • Intracellular demonstration of active TGF-β1 in B cells and plasma cells of autoimmune mice. IgG-bound TGF-β1 suppresses neutrophil function and host defense against Staphylococcus aureus infection
    • Caver T.E., O'Sullivan F.X., Gold L.I., Gresham H.D. Intracellular demonstration of active TGF-β1 in B cells and plasma cells of autoimmune mice. IgG-bound TGF-β1 suppresses neutrophil function and host defense against Staphylococcus aureus infection. J. Clin. Invest. 98:1996;2496-2506.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2496-2506
    • Caver, T.E.1    O'Sullivan, F.X.2    Gold, L.I.3    Gresham, H.D.4
  • 32
    • 0027249366 scopus 로고
    • A first or dominant immunization. II. Induced immunoglobulin carries transforming growth factor beta and suppresses cytolytic T cell responses to unrelated alloantigens
    • Stach R.M., Rowley D.A. A first or dominant immunization. II. Induced immunoglobulin carries transforming growth factor beta and suppresses cytolytic T cell responses to unrelated alloantigens. J. Exp. Med. 178:1993;841-852.
    • (1993) J. Exp. Med. , vol.178 , pp. 841-852
    • Stach, R.M.1    Rowley, D.A.2
  • 33
    • 0025763238 scopus 로고
    • Defective neutrophil function in the autoimmune mouse strain MRL/lpr. Potential role of transforming growth factor-beta
    • Gresham H.D., Ray C.J., O'Sullivan F.X. Defective neutrophil function in the autoimmune mouse strain MRL/lpr. Potential role of transforming growth factor-beta. J. Immunol. 146:1991;3911-3921.
    • (1991) J. Immunol. , vol.146 , pp. 3911-3921
    • Gresham, H.D.1    Ray, C.J.2    O'Sullivan, F.X.3
  • 34
    • 0028800984 scopus 로고
    • A transforming growth factor beta- like immunosuppressive factor in immunoglobulin G-binding factor
    • Bouchard C., Galinha A., Tartour E., Fridman W.H., Sautes C. A transforming growth factor beta- like immunosuppressive factor in immunoglobulin G-binding factor. J. Exp. Med. 182:1995;1717-1726.
    • (1995) J. Exp. Med. , vol.182 , pp. 1717-1726
    • Bouchard, C.1    Galinha, A.2    Tartour, E.3    Fridman, W.H.4    Sautes, C.5
  • 35
    • 0026548073 scopus 로고
    • Dominant negative mutants of transforming growth factor-β1 inhibit the secretion of different transforming growth factor-β isoforms
    • Lopez A.R., Cook J., Deiningen P.L., Derynck R. Dominant negative mutants of transforming growth factor-β1 inhibit the secretion of different transforming growth factor-β isoforms. Mol. Cell. Biol. 12:1992;1674-1679.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1674-1679
    • Lopez, A.R.1    Cook, J.2    Deiningen, P.L.3    Derynck, R.4
  • 37
    • 0024382711 scopus 로고
    • Inhibition of endothelial cell movement by pericytes and smooth muscle cells: Activation of a latent transforming growth factor-β1-like molecule by plasmin during co-culture
    • Sato Y., Rifkin D.B. Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-β1-like molecule by plasmin during co-culture. J. Cell. Biol. 109:1989;309-315.
    • (1989) J. Cell. Biol. , vol.109 , pp. 309-315
    • Sato, Y.1    Rifkin, D.B.2
  • 38
    • 0026059613 scopus 로고
    • Cellular activation of latent transforming growth factor-β requires binding to the cation-independent mannose 6-phosphate/ insulin-like growth factor type II receptor
    • Dennis P.A., Rifkin D.B. Cellular activation of latent transforming growth factor-β requires binding to the cation-independent mannose 6-phosphate/ insulin-like growth factor type II receptor. Proc. Natl. Acad. Sci. 88:1991;580-584.
    • (1991) Proc. Natl. Acad. Sci. , vol.88 , pp. 580-584
    • Dennis, P.A.1    Rifkin, D.B.2
  • 39
    • 0025695183 scopus 로고
    • Immunoregulatory role of transforming growth factor (TGF-) in development of killer cells: Comparison of active and latent TGF-1
    • Wallick S.C., Figari I.S., Morris R.E., Levison A.D., Palladino M.A. Immunoregulatory role of transforming growth factor (TGF-) in development of killer cells: comparison of active and latent TGF-1. J. Exp. Med. 172:1990;1777-1784.
    • (1990) J. Exp. Med. , vol.172 , pp. 1777-1784
    • Wallick, S.C.1    Figari, I.S.2    Morris, R.E.3    Levison, A.D.4    Palladino, M.A.5
  • 40
    • 0028953810 scopus 로고
    • Transforming factor growth and cell cycle regulation
    • Alexandrow M.G., Moses H.L. Transforming factor growth and cell cycle regulation. Cancer Res. 55:1995;1452-1457.
    • (1995) Cancer Res. , vol.55 , pp. 1452-1457
    • Alexandrow, M.G.1    Moses, H.L.2
  • 41
    • 0025104027 scopus 로고
    • TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights
    • Moses H.L., Yang E.Y., Pietentol J.A. TGF-β stimulation and inhibition of cell proliferation: new mechanistic insights. Cell. 63:1990;245-247.
    • (1990) Cell , vol.63 , pp. 245-247
    • Moses, H.L.1    Yang, E.Y.2    Pietentol, J.A.3
  • 42
    • 0027213710 scopus 로고
    • Pleiotropic effects of transforming growth factor-beta on cells of the immune system
    • Ruscetti F., Varesio L., Ochoa A., Ortaldo J. Pleiotropic effects of transforming growth factor-beta on cells of the immune system. Ann. NY Acad. Sci. 685:1993;488-500.
    • (1993) Ann. NY Acad. Sci. , vol.685 , pp. 488-500
    • Ruscetti, F.1    Varesio, L.2    Ochoa, A.3    Ortaldo, J.4
  • 43
    • 0026309211 scopus 로고
    • Transforming growth factor beta and the immune system
    • Ruscetti F.W., Palladino M.A. Transforming growth factor beta and the immune system. Prog. Growth factor Res. 3:1991;159-175.
    • (1991) Prog. Growth Factor Res. , vol.3 , pp. 159-175
    • Ruscetti, F.W.1    Palladino, M.A.2
  • 44
    • 0023029023 scopus 로고
    • Transforming growth factor-β is an important immunomodulating protein for human B lymphocytes
    • Kehrl J.H., Roberts A.B., Wakefield L.M., Jakowlew S., Sporn M.B., Fauci A.S. Transforming growth factor-β is an important immunomodulating protein for human B lymphocytes. J. Immunol. 137:1986;3855-3860.
    • (1986) J. Immunol. , vol.137 , pp. 3855-3860
    • Kehrl, J.H.1    Roberts, A.B.2    Wakefield, L.M.3    Jakowlew, S.4    Sporn, M.B.5    Fauci, A.S.6
  • 46
    • 0025780301 scopus 로고
    • Transforming growth factor-β suppresses human B lymphocyte Ig production by inhibiting synthesis and the switch from the membrane form to the secreted form of Ig mRNA
    • Kehrl J.H., Thevenin C., Rieckmann P., Fauci A.S. Transforming growth factor-β suppresses human B lymphocyte Ig production by inhibiting synthesis and the switch from the membrane form to the secreted form of Ig mRNA. J. Immunol. 146:1991;4016-4022.
    • (1991) J. Immunol. , vol.146 , pp. 4016-4022
    • Kehrl, J.H.1    Thevenin, C.2    Rieckmann, P.3    Fauci, A.S.4
  • 47
    • 0022617915 scopus 로고
    • Effects of transforming growth factor β on the functions of natural killer cells: Depressed cytolytic activity and blunting of interferon responsiveness
    • Rook A.H., Kehrl J.H., Wakefield L.M., Roberts A.B., Sporn M.B., Burlington D.B., Lane H.C., Fauci A.S. Effects of transforming growth factor β on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness. J. Immunol. 136:1986;3916-3920.
    • (1986) J. Immunol. , vol.136 , pp. 3916-3920
    • Rook, A.H.1    Kehrl, J.H.2    Wakefield, L.M.3    Roberts, A.B.4    Sporn, M.B.5    Burlington, D.B.6    Lane, H.C.7    Fauci, A.S.8
  • 48
    • 0023696831 scopus 로고
    • The glioblastoma-derived T-cell suppressor factor/transforming growth factor β2 inhibits the generation of lymphokine-activated killer (LAK) cells
    • Kuppner M.C., Hamou M.F., Bodmer S., Fontana A., De Tribolet N. The glioblastoma-derived T-cell suppressor factor/transforming growth factor β2 inhibits the generation of lymphokine-activated killer (LAK) cells. Int. J. Cancer. 42:1988;562-567.
    • (1988) Int. J. Cancer , vol.42 , pp. 562-567
    • Kuppner, M.C.1    Hamou, M.F.2    Bodmer, S.3    Fontana, A.4    De Tribolet, N.5
  • 51
    • 0025908130 scopus 로고
    • Mechanistic studies of transforming growth factor-beta inhibition of IL-2 dependent activation of CD3-large granular lymphocyte functions. Regulation of IL-2Rβ (p75) signal transduction
    • Ortaldo J.R., Mason A.T., O'Shea J.J., Smith M.J., Falk L.A., Kennedy A.C.S., Longo D.L., Ruscetti F.W. Mechanistic studies of transforming growth factor-beta inhibition of IL-2 dependent activation of CD3-large granular lymphocyte functions. Regulation of IL-2Rβ (p75) signal transduction. J. Immunol. 146:1991;3791-3798.
    • (1991) J. Immunol. , vol.146 , pp. 3791-3798
    • Ortaldo, J.R.1    Mason, A.T.2    O'Shea, J.J.3    Smith, M.J.4    Falk, L.A.5    Kennedy, A.C.S.6    Longo, D.L.7    Ruscetti, F.W.8
  • 52
    • 0028299062 scopus 로고
    • T helper type 1 development of naïve CD4+T cells requires the coordinate action of interleukin 12 and interferon gamma and is inhibited by transforming growth factor beta
    • Schmitt E., Hoehn P., Huels C., Goedert S., Palm N., Rude E., Germann T. T helper type 1 development of naïve CD4+T cells requires the coordinate action of interleukin 12 and interferon gamma and is inhibited by transforming growth factor beta. Eur. J. Immunol. 24:1994;793-798.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 793-798
    • Schmitt, E.1    Hoehn, P.2    Huels, C.3    Goedert, S.4    Palm, N.5    Rude, E.6    Germann, T.7
  • 53
    • 0031180973 scopus 로고    scopus 로고
    • TGF-β inhibits IL-2 induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes
    • Bright J.J., Kerr L.D., Sriram S. TGF-β inhibits IL-2 induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes. J. Immunology. 159:1997;175-183.
    • (1997) J. Immunology , vol.159 , pp. 175-183
    • Bright, J.J.1    Kerr, L.D.2    Sriram, S.3
  • 54
    • 8044250881 scopus 로고    scopus 로고
    • Regulation of the interleukin (IL)-12R beta 2 subunit expression in the developing T helper 1 (Th1) and Th2 cells
    • Szabo S.J., Dighe A.S., Gubler U., Murphy K.M. Regulation of the interleukin (IL)-12R beta 2 subunit expression in the developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 185:1997;817-824.
    • (1997) J. Exp. Med. , vol.185 , pp. 817-824
    • Szabo, S.J.1    Dighe, A.S.2    Gubler, U.3    Murphy, K.M.4
  • 55
    • 0031080948 scopus 로고    scopus 로고
    • Reciprocal IFN-gamma and TGF-beta response regulate the occurrence of mucosal inflammation
    • Strober W., Kelsall B., Fuss I., Marth T., Ludviksson B., Ehrhardt R. Reciprocal IFN-gamma and TGF-beta response regulate the occurrence of mucosal inflammation. Immunol. Today. 18:1997;61-64.
    • (1997) Immunol. Today , vol.18 , pp. 61-64
    • Strober, W.1    Kelsall, B.2    Fuss, I.3    Marth, T.4    Ludviksson, B.5    Ehrhardt, R.6
  • 56
    • 0028191375 scopus 로고
    • Control of nitric oxide synthase expression by transforming growth factor-beta: Implications for homeostasis
    • Vodovotz Y., Bogdan C. Control of nitric oxide synthase expression by transforming growth factor-beta: implications for homeostasis. Prog. Growth Factor Res. 5:1994;341-351.
    • (1994) Prog. Growth Factor Res. , vol.5 , pp. 341-351
    • Vodovotz, Y.1    Bogdan, C.2
  • 57
    • 0027203305 scopus 로고
    • Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor-β
    • Vodovotz Y., Bogdan C., Paik J., Xie Q.W., Nathan C. Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor-β J. Exp. Med. 178:1993;605-613.
    • (1993) J. Exp. Med. , vol.178 , pp. 605-613
    • Vodovotz, Y.1    Bogdan, C.2    Paik, J.3    Xie, Q.W.4    Nathan, C.5
  • 58
    • 0023726231 scopus 로고
    • Deactivation of macrophages by transforming growth factor β
    • Tsunawaki S., Sporn M., Ding A., Nathan C. Deactivation of macrophages by transforming growth factor β Nature. 334:1988;260-262.
    • (1988) Nature , vol.334 , pp. 260-262
    • Tsunawaki, S.1    Sporn, M.2    Ding, A.3    Nathan, C.4
  • 59
    • 0032529414 scopus 로고    scopus 로고
    • Low dose TGF-β attenuates IL-12 responsiveness in murine Th cells
    • Gorham J.D., Guler M.L., Fenoglio D., Gubler U., Murphy K.M. Low dose TGF-β attenuates IL-12 responsiveness in murine Th cells. J. Immunol. 161:1998;1664-1670.
    • (1998) J. Immunol. , vol.161 , pp. 1664-1670
    • Gorham, J.D.1    Guler, M.L.2    Fenoglio, D.3    Gubler, U.4    Murphy, K.M.5
  • 60
    • 0023746462 scopus 로고
    • Transforming growth factor-beta 1 modulates the expression of class II histocompatibility antigens on human cells
    • Czarniecki C.W., Chiu H.H., Wong G.H.W., McCabe S.M., Palladino M.A. Transforming growth factor-beta 1 modulates the expression of class II histocompatibility antigens on human cells. J. Immunol. 140:1988;4217-4223.
    • (1988) J. Immunol. , vol.140 , pp. 4217-4223
    • Czarniecki, C.W.1    Chiu, H.H.2    Wong, G.H.W.3    McCabe, S.M.4    Palladino, M.A.5
  • 61
    • 0027221555 scopus 로고
    • Transforming growth factor β inhibits E-selectin expression on human endothelial cells
    • Gamble J.R., Khew-Goodall Y., Vadas M.A. Transforming growth factor β inhibits E-selectin expression on human endothelial cells. J. Immunol. 150:1993;4494-4503.
    • (1993) J. Immunol. , vol.150 , pp. 4494-4503
    • Gamble, J.R.1    Khew-Goodall, Y.2    Vadas, M.A.3
  • 63
    • 0025707731 scopus 로고
    • Aqueous humor contains transforming growth factor-β And a small (less than 3500 daltons) inhibitor of thymocyte proliferation
    • Granstein R.D., Straszewski R., Knisely T.L., Zeira E., Nazareno R., Latina M., Albert D.M. Aqueous humor contains transforming growth factor-β and a small (less than 3500 daltons) inhibitor of thymocyte proliferation. J. Immunol. 144:1990;3021.
    • (1990) J. Immunol. , vol.144 , pp. 3021
    • Granstein, R.D.1    Straszewski, R.2    Knisely, T.L.3    Zeira, E.4    Nazareno, R.5    Latina, M.6    Albert, D.M.7
  • 64
    • 0025968739 scopus 로고
    • Immune privilege extended to allogeneic tumor cells in the vitreous cavity
    • Jiang L.Q., Streilein J.W. Immune privilege extended to allogeneic tumor cells in the vitreous cavity. Invest. Ophthalmol. Vis. 32:1991;224.
    • (1991) Invest. Ophthalmol. Vis. , vol.32 , pp. 224
    • Jiang, L.Q.1    Streilein, J.W.2
  • 65
    • 0025307761 scopus 로고
    • Murine pregnancy decidua produces a unique immunosuppressive molecule related to transforming growth factor beta-2
    • Clark D.A., Flanders K.C., Banwatt D., Millar-Book W., Manuel J., Stedronska-Clark J., Rowley B. Murine pregnancy decidua produces a unique immunosuppressive molecule related to transforming growth factor beta-2. J. Immunol. 144:1990;3008-3014.
    • (1990) J. Immunol. , vol.144 , pp. 3008-3014
    • Clark, D.A.1    Flanders, K.C.2    Banwatt, D.3    Millar-Book, W.4    Manuel, J.5    Stedronska-Clark, J.6    Rowley, B.7
  • 66
    • 0031965426 scopus 로고    scopus 로고
    • Transforming growth factor and the endometrium
    • Godkin J.D., Dore J.J. Transforming growth factor and the endometrium. Rev. in Reproduction. 3:1998;1-6.
    • (1998) Rev. in Reproduction. , vol.3 , pp. 1-6
    • Godkin, J.D.1    Dore, J.J.2
  • 68
    • 0028982243 scopus 로고
    • TGF-β2 decreases migration of lymphocytes in vitro and homing of cells into central nervous system in vivo
    • Fabry Z., Topham D.J., Fee D., Herlein J., Carlino A., Hart M.N., Sriram S. TGF-β2 decreases migration of lymphocytes in vitro and homing of cells into central nervous system in vivo. J. Immunol. 155:1995;325.
    • (1995) J. Immunol. , vol.155 , pp. 325
    • Fabry, Z.1    Topham, D.J.2    Fee, D.3    Herlein, J.4    Carlino, A.5    Hart, M.N.6    Sriram, S.7
  • 69
    • 0029665787 scopus 로고    scopus 로고
    • Transforming growth factors-beta s: A multifunctional cytokine family: Implication in the regulation of adrenocortical cell endocrine functions
    • Chambaz E.M., Souchelnitskiy S., Pellerin S., Defaye G., Cochet C., Feige J.J. Transforming growth factors-beta s: a multifunctional cytokine family: implication in the regulation of adrenocortical cell endocrine functions. Horm. Res. 45:1996;222.
    • (1996) Horm. Res. , vol.45 , pp. 222
    • Chambaz, E.M.1    Souchelnitskiy, S.2    Pellerin, S.3    Defaye, G.4    Cochet, C.5    Feige, J.J.6
  • 70
    • 0000145814 scopus 로고    scopus 로고
    • Immunological tolerance
    • W.E. Paul. Philadelphia: Lippincott-Raven Publishers
    • Schwartz R.H. Immunological tolerance. Paul W.E. Fundamental immunology. 1999;701-739 Lippincott-Raven Publishers, Philadelphia.
    • (1999) Fundamental Immunology , pp. 701-739
    • Schwartz, R.H.1
  • 71
    • 0030951069 scopus 로고    scopus 로고
    • A vision of cell death: Insights into immune privilege
    • Ferguson T.A., Griffith T.S. A vision of cell death: insights into immune privilege. Immunol. Rev. 156:1997;167-184.
    • (1997) Immunol. Rev. , vol.156 , pp. 167-184
    • Ferguson, T.A.1    Griffith, T.S.2
  • 73
    • 0030886870 scopus 로고    scopus 로고
    • Aqueous humor induces transforming growth factor-beta (TGF-beta)-producing regulatory T-cells
    • Taylor A.W., Alard P., Yee D.G., Streilein J.W. Aqueous humor induces transforming growth factor-beta (TGF-beta)-producing regulatory T-cells. Current Eye Research. 16:1997;900-908.
    • (1997) Current Eye Research , vol.16 , pp. 900-908
    • Taylor, A.W.1    Alard, P.2    Yee, D.G.3    Streilein, J.W.4
  • 75
    • 0031958314 scopus 로고    scopus 로고
    • Upregulation of transforming growth factor-beta after panretinal photocoagulation
    • Ishida K., Yoshimura N., Yoshida M., Honda Y. Upregulation of transforming growth factor-beta after panretinal photocoagulation. Invest. Ophthal. Vis. Sci. 39:1998;801-807.
    • (1998) Invest. Ophthal. Vis. Sci. , vol.39 , pp. 801-807
    • Ishida, K.1    Yoshimura, N.2    Yoshida, M.3    Honda, Y.4
  • 76
    • 0032030582 scopus 로고    scopus 로고
    • A novel role for TGF-beta and IL-10 in the induction of immune privilege
    • D'Orazio T.J., Niederkorn J.Y. A novel role for TGF-beta and IL-10 in the induction of immune privilege. J. Immunol. 160:1998;2089-2098.
    • (1998) J. Immunol. , vol.160 , pp. 2089-2098
    • D'Orazio, T.J.1    Niederkorn, J.Y.2
  • 77
    • 0030847840 scopus 로고    scopus 로고
    • On the mechanisms by which transforming growth factor-beta 2 alters antigen-presenting abilities of macrophages on T cell activation
    • 1656
    • Takeuchi, M. Kosiewicz, M.M. Alard, P. Streilein, J.W. On the mechanisms by which transforming growth factor-beta 2 alters antigen-presenting abilities of macrophages on T cell activation, Eur. J Immunol. 27, 1648, 1656.
    • Eur. J Immunol. , vol.27 , pp. 1648
    • Takeuchi, M.1    Kosiewicz, M.M.2    Alard, P.3    Streilein, J.W.4
  • 78
    • 0030239618 scopus 로고    scopus 로고
    • Intraocular injection of class II-restricted peptide induces an unexpected population of CD8 regulatory cells
    • Kosiewicz M.M., Streilein J.W. Intraocular injection of class II-restricted peptide induces an unexpected population of CD8 regulatory cells. J. Immunol. 157:1996;1905-1912.
    • (1996) J. Immunol. , vol.157 , pp. 1905-1912
    • Kosiewicz, M.M.1    Streilein, J.W.2
  • 79
    • 0031569520 scopus 로고    scopus 로고
    • Immune deviation in relation to ocular immune privilege
    • Streilein J.W., Ksander B.R., Taylor A.W. Immune deviation in relation to ocular immune privilege. J. Immunol. 158:1997;3557-3560.
    • (1997) J. Immunol. , vol.158 , pp. 3557-3560
    • Streilein, J.W.1    Ksander, B.R.2    Taylor, A.W.3
  • 80
    • 0025951644 scopus 로고
    • Transforming growth factor beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphocyte secretion pattern and cell surface phenotype
    • Swain S.L., Huston G., Tonkonogy S., Weinberg A. Transforming growth factor beta and IL-4 cause helper T cell precursors to develop into distinct effector helper cells that differ in lymphocyte secretion pattern and cell surface phenotype. J. Immunol. 147:1991;2991-3000.
    • (1991) J. Immunol. , vol.147 , pp. 2991-3000
    • Swain, S.L.1    Huston, G.2    Tonkonogy, S.3    Weinberg, A.4
  • 81
  • 83
    • 0032529220 scopus 로고    scopus 로고
    • TGF-β inhibits IL-12 induced activation of Jak-STAT pathway in T lymphocytes
    • Bright J.J., Sriram S. TGF-β inhibits IL-12 induced activation of Jak-STAT pathway in T lymphocytes. J. Immunol. 161:1998;1772-1777.
    • (1998) J. Immunol. , vol.161 , pp. 1772-1777
    • Bright, J.J.1    Sriram, S.2
  • 84
    • 0031574013 scopus 로고    scopus 로고
    • Regulatory cells generated by testicular tolerization to retinal S-antigen: Possible involvement of IL-4, IL-10, and TGF-beta in the suppression of experimental autoimmune uveoretinitis
    • Yotsukura J., Huang H., Singh A.K., Shichi H. Regulatory cells generated by testicular tolerization to retinal S-antigen: possible involvement of IL-4, IL-10, and TGF-beta in the suppression of experimental autoimmune uveoretinitis. Cell. Immunol. 182:1998;89-98.
    • (1998) Cell. Immunol. , vol.182 , pp. 89-98
    • Yotsukura, J.1    Huang, H.2    Singh, A.K.3    Shichi, H.4
  • 85
    • 0025895269 scopus 로고
    • Mechanism of control of trophoblast invasion in situ
    • Graham C.H., Lala P.K. Mechanism of control of trophoblast invasion in situ. J. Cell. Physiol. 148:1991;228-234.
    • (1991) J. Cell. Physiol. , vol.148 , pp. 228-234
    • Graham, C.H.1    Lala, P.K.2
  • 88
    • 0032573680 scopus 로고    scopus 로고
    • Phenotype, function, and in vivo migration and survival of allogeneic dendritic cells progenitors genetically engineered to express TGF-beta
    • Lee W.C., Zhong C., Qian S., Wan Y., Gauldie J., Mi Z., Robbins P.D., Thomson A.W., Lu L. Phenotype, function, and in vivo migration and survival of allogeneic dendritic cells progenitors genetically engineered to express TGF-beta. Transplantation. 66:1998;1810-1817.
    • (1998) Transplantation , vol.66 , pp. 1810-1817
    • Lee, W.C.1    Zhong, C.2    Qian, S.3    Wan, Y.4    Gauldie, J.5    Mi, Z.6    Robbins, P.D.7    Thomson, A.W.8    Lu, L.9
  • 90
    • 0032571370 scopus 로고    scopus 로고
    • Anti-inflammatory effect of transforming growth factor-beta 1 in myoblast transplantation
    • Merly F., Huard C., Asselin I., Robbins P.D., Tremblay J.P. Anti-inflammatory effect of transforming growth factor-beta 1 in myoblast transplantation. Transplantation. 65:1998;793-799.
    • (1998) Transplantation , vol.65 , pp. 793-799
    • Merly, F.1    Huard, C.2    Asselin, I.3    Robbins, P.D.4    Tremblay, J.P.5
  • 91
    • 0029844582 scopus 로고    scopus 로고
    • Gene transfer of transforming growth factor-beta 1 prolongs murine cardiac allograft survival by inhibiting cell-mediated immunity
    • Qin L., Ding Y., Bromberg J.S. Gene transfer of transforming growth factor-beta 1 prolongs murine cardiac allograft survival by inhibiting cell-mediated immunity. Human Gene Therapy. 7:1996;1981-1988.
    • (1996) Human Gene Therapy , vol.7 , pp. 1981-1988
    • Qin, L.1    Ding, Y.2    Bromberg, J.S.3
  • 92
    • 0029986165 scopus 로고    scopus 로고
    • Regulatory activity of endogenous and exogenous transforming growth factor beta in experimental intestinal immunopathology
    • Mowat A.M., Garside P., Fitton L.A., Higley H.R., Carlino J.A. Regulatory activity of endogenous and exogenous transforming growth factor beta in experimental intestinal immunopathology. Growth Factors. 13:1996;75-85.
    • (1996) Growth Factors. , vol.13 , pp. 75-85
    • Mowat, A.M.1    Garside, P.2    Fitton, L.A.3    Higley, H.R.4    Carlino, J.A.5
  • 93
    • 0026009177 scopus 로고
    • Differential regulation of transforming growth factor beta and inteleukin 2 genes in human T cells: Demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction
    • Li B., Sehajpal P.K., Khanna A., Vlassara H., Cerami A., Stenzel K.H., Suthanthiran M. Differential regulation of transforming growth factor beta and inteleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction. J. Exp. Med. 174:1991;1259-1262.
    • (1991) J. Exp. Med. , vol.174 , pp. 1259-1262
    • Li, B.1    Sehajpal, P.K.2    Khanna, A.3    Vlassara, H.4    Cerami, A.5    Stenzel, K.H.6    Suthanthiran, M.7
  • 94
    • 0033608710 scopus 로고    scopus 로고
    • Transforming growth factor (TGF)-beta mimics and anti-TGF-beta antibody abrogates the in vivo effects of cyclosporine-Demonstration of a direct role of TGF-beta in immunosuppression and nephrotoxicity of cyclosporine
    • Khanna A.K., Cairns V.R., Becker C.G., Hosenpud J.D. Transforming growth factor (TGF)-beta mimics and anti-TGF-beta antibody abrogates the in vivo effects of cyclosporine-Demonstration of a direct role of TGF-beta in immunosuppression and nephrotoxicity of cyclosporine. Transplantation. 67:1999;882-889.
    • (1999) Transplantation. , vol.67 , pp. 882-889
    • Khanna, A.K.1    Cairns, V.R.2    Becker, C.G.3    Hosenpud, J.D.4
  • 96
    • 0033066588 scopus 로고    scopus 로고
    • Oral tolerance: Mechanisms and therapeutic applications
    • Faria A.M., Weiner H.L. Oral tolerance: mechanisms and therapeutic applications. Adv. Immunol. 73:1999;153-264.
    • (1999) Adv. Immunol. , vol.73 , pp. 153-264
    • Faria, A.M.1    Weiner, H.L.2
  • 97
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen Y., Kuchroo V.K., Inobe J., Hafler D.A., Weiner H.L. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science. 265:1994;1237-1240.
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 100
    • 0032403697 scopus 로고    scopus 로고
    • Control of immune pathology by regulatory T cells
    • Mason D., Powrie F. Control of immune pathology by regulatory T cells. Current Opinion in Immunology. 10:1998;649-655.
    • (1998) Current Opinion in Immunology. , vol.10 , pp. 649-655
    • Mason, D.1    Powrie, F.2
  • 101
    • 0027509812 scopus 로고
    • +T cell subset that inhibits this autoimmune potential
    • +T cell subset that inhibits this autoimmune potential. J. Exp. Med. 177:1993;627-636.
    • (1993) J. Exp. Med. , vol.177 , pp. 627-636
    • Fowell, D.1    Mason, D.2
  • 102
    • 0030996472 scopus 로고    scopus 로고
    • -thymocytes in the prevention of autoimmune diabetes
    • -thymocytes in the prevention of autoimmune diabetes. Biochem. Soc. Trans. 25:1997;620-624.
    • (1997) Biochem. Soc. Trans. , vol.25 , pp. 620-624
    • Seddon, B.1    Masson, D.2
  • 104
    • 0033579883 scopus 로고    scopus 로고
    • Regulatory T cells in the control of autoimmunity: The essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC(-) cells and CD4(+)CD8(-) thymocytes
    • Seddon B., Mason D. Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC(-) cells and CD4(+)CD8(-) thymocytes. J. Exp. Med. 189:1999;279-288.
    • (1999) J. Exp. Med. , vol.189 , pp. 279-288
    • Seddon, B.1    Mason, D.2
  • 105
    • 0012798333 scopus 로고    scopus 로고
    • Phenotypes of TGFβ knockout mice
    • S.K. Durum, & K. Mueege. Totowa: Humana Press
    • Kallapur S., Shull M., Doetschman T. Phenotypes of TGFβ knockout mice. Durum S.K., Mueege K. Cytokine knockouts. 1998;315-334 Humana Press, Totowa.
    • (1998) Cytokine Knockouts , pp. 315-334
    • Kallapur, S.1    Shull, M.2    Doetschman, T.3
  • 106
    • 0001376753 scopus 로고    scopus 로고
    • The transforming growth factor-β1 knockout mouse: The phenotype and its implications for TGFβ1 function
    • S.K. Durum, & K. Muegge. Totowa: Humana Press
    • Kulkarni A.B., Letterio J.J. The transforming growth factor-β1 knockout mouse: the phenotype and its implications for TGFβ1 function. Durum S.K., Muegge K. Cytokine knockouts. 1998;369-400 Humana Press, Totowa.
    • (1998) Cytokine Knockouts , pp. 369-400
    • Kulkarni, A.B.1    Letterio, J.J.2
  • 110
    • 0029948826 scopus 로고    scopus 로고
    • The thymus and central tolerance
    • Sprent J. The thymus and central tolerance. Horm. Met. Res. 28:1996;294-295.
    • (1996) Horm. Met. Res. , vol.28 , pp. 294-295
    • Sprent, J.1
  • 111
    • 0029440221 scopus 로고
    • Central tolerance of T cells
    • Sprent J. Central tolerance of T cells. Int. Rev. Immunol. 13:1995;95-105.
    • (1995) Int. Rev. Immunol. , vol.13 , pp. 95-105
    • Sprent, J.1
  • 112
    • 0028230798 scopus 로고
    • Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor β
    • Takahama Y., Letterio J.J., Harumi-Suzuki H., Farr A.G., Singer A. Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor β J. Exp. Med. 179:1994;1495-1506.
    • (1994) J. Exp. Med. , vol.179 , pp. 1495-1506
    • Takahama, Y.1    Letterio, J.J.2    Harumi-Suzuki, H.3    Farr, A.G.4    Singer, A.5
  • 115
    • 0033579816 scopus 로고    scopus 로고
    • B7-1 or B7-2 is required to produce the lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)
    • Mandelbrot D.A., McAdam A.J., Sharpe A.H. B7-1 or B7-2 is required to produce the lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4). J. Exp. Med. 189:1999;435-440.
    • (1999) J. Exp. Med. , vol.189 , pp. 435-440
    • Mandelbrot, D.A.1    McAdam, A.J.2    Sharpe, A.H.3
  • 116
  • 117
    • 0032145434 scopus 로고    scopus 로고
    • Kinetics of expression of costimulatory molecules and their ligands in murine relapsing experimental autoimmune encephalomyelitis
    • Issazadeh S., Navikas V., Schaub M., Sayegh M., Khoury S. Kinetics of expression of costimulatory molecules and their ligands in murine relapsing experimental autoimmune encephalomyelitis. J. Immunol. 161:1998;1102-1104.
    • (1998) J. Immunol. , vol.161 , pp. 1102-1104
    • Issazadeh, S.1    Navikas, V.2    Schaub, M.3    Sayegh, M.4    Khoury, S.5
  • 118
    • 0026607639 scopus 로고
    • Target organ-specific up-regulation of the MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with EAE
    • Weinberg A.D., Whitman R., Swain S.L., Morrison W.J., Wyrick G., Hoy C., Vandenbark A.A., Offner H. Target organ-specific up-regulation of the MRC OX-40 marker and selective production of Th1 lymphokine mRNA by encephalitogenic T helper cells isolated from the spinal cord of rats with EAE. J. Immunol. 148:1992;2109-2117.
    • (1992) J. Immunol. , vol.148 , pp. 2109-2117
    • Weinberg, A.D.1    Whitman, R.2    Swain, S.L.3    Morrison, W.J.4    Wyrick, G.5    Hoy, C.6    Vandenbark, A.A.7    Offner, H.8
  • 119
    • 0025744497 scopus 로고
    • Co-stimulation of T cell proliferation by transforming growth factor-beta 1
    • Lee H.M., Rich S. Co-stimulation of T cell proliferation by transforming growth factor-beta 1. J. Immunol. 147:1991;1127-1133.
    • (1991) J. Immunol. , vol.147 , pp. 1127-1133
    • Lee, H.M.1    Rich, S.2
  • 120
    • 0033579820 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc
    • Genestier L., Kasibhatla S., Brunner T., Green D.R. Transforming growth factor beta 1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc. J. Exp. Med. 189:1999;231-239.
    • (1999) J. Exp. Med. , vol.189 , pp. 231-239
    • Genestier, L.1    Kasibhatla, S.2    Brunner, T.3    Green, D.R.4
  • 121
    • 0030030037 scopus 로고    scopus 로고
    • Fas- And activation-induced apoptosis are reduced in human T cells preactivated in the presence of TGF-beta 1
    • Cerwenka A., Kovar H., Majdic O., Holter W. Fas- and activation-induced apoptosis are reduced in human T cells preactivated in the presence of TGF-beta 1. J. Immunol. 156:1996;459-464.
    • (1996) J. Immunol. , vol.156 , pp. 459-464
    • Cerwenka, A.1    Kovar, H.2    Majdic, O.3    Holter, W.4
  • 123
    • 0031716664 scopus 로고    scopus 로고
    • IL-4 is a differentiation factor for transforming growth factor-β secreting Th3 cells and oral administration of IL-4 enhances oral tolerance in experimental allergic encephalomyelitis
    • Inobe J-I, Slavin A.J., Komagata Y., Chen Y., Liu L., Weiner H.L. IL-4 is a differentiation factor for transforming growth factor-β secreting Th3 cells and oral administration of IL-4 enhances oral tolerance in experimental allergic encephalomyelitis. Eur. J. Immunol. 28:1998;2780-2790.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2780-2790
    • Inobe, J.-I.1    Slavin, A.J.2    Komagata, Y.3    Chen, Y.4    Liu, L.5    Weiner, H.L.6
  • 124
    • 0027198859 scopus 로고
    • Thrombin-induced release of active basic fibroblast growth factor-heparan sulfate complexes from subendothelial extracellular matrix
    • Benerzra M., Vlodavsky I.L., Ishai-Michaeli R., Neufeld G., Bar-Shavit R. Thrombin-induced release of active basic fibroblast growth factor-heparan sulfate complexes from subendothelial extracellular matrix. Blood. 81:1993;3324-3331.
    • (1993) Blood , vol.81 , pp. 3324-3331
    • Benerzra, M.1    Vlodavsky, I.L.2    Ishai-Michaeli, R.3    Neufeld, G.4    Bar-Shavit, R.5
  • 125
    • 0032531423 scopus 로고    scopus 로고
    • Transforming growth factor beta-1 (TGF-β1) somatic gene therapy prevents autoimmune disease in NOD mice
    • Piccirillo C., Chang Y., Prud'homme G.J. Transforming growth factor beta-1 (TGF-β1) somatic gene therapy prevents autoimmune disease in NOD mice. J. Immunol. 161:1998;3950-3956.
    • (1998) J. Immunol. , vol.161 , pp. 3950-3956
    • Piccirillo, C.1    Chang, Y.2    Prud'homme, G.J.3
  • 126
    • 0033543127 scopus 로고    scopus 로고
    • Prevention of experimental allergic encephalomyelitis by intramuscular gene therapy with cytokine-encoding plasmid vectors
    • Piccirillo C., Prud'homme G.J. Prevention of experimental allergic encephalomyelitis by intramuscular gene therapy with cytokine-encoding plasmid vectors. Hum. Gen. Ther. 10:1999;1915-1922.
    • (1999) Hum. Gen. Ther. , vol.10 , pp. 1915-1922
    • Piccirillo, C.1    Prud'homme, G.J.2
  • 127
    • 0343261100 scopus 로고
    • Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene therapy ameliorates experimental colitis in rats
    • Raz E., Lotz M., Bairs S.M., Berry C.C., Eisenberg R.A., Carson D. Modulation of disease activity in murine systemic lupus erythematosus by cytokine gene therapy ameliorates experimental colitis in rats. Eur. J. Gastroent. Hepatol. 7:1995;341-347.
    • (1995) Eur. J. Gastroent. Hepatol. , vol.7 , pp. 341-347
    • Raz, E.1    Lotz, M.2    Bairs, S.M.3    Berry, C.C.4    Eisenberg, R.A.5    Carson, D.6
  • 128
    • 0033007567 scopus 로고    scopus 로고
    • Regulation of immune responses through inhibitory receptors
    • Long O.L. Regulation of immune responses through inhibitory receptors. Ann. Rev. Immunol. 17:1999;875-904.
    • (1999) Ann. Rev. Immunol. , vol.17 , pp. 875-904
    • Long, O.L.1
  • 129
    • 0032921601 scopus 로고    scopus 로고
    • Transforming growth factor-beta-induced expression of CD94/NKG2a inhibitory receptors in human T lymphocytes
    • Bertone S., Schiavetti F., Bellomo R., Vitale C., Ponte M., Moretta L., Mingari M.C. Transforming growth factor-beta-induced expression of CD94/NKG2a inhibitory receptors in human T lymphocytes. Eur. J. Immunol. 29:1999;23-29.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 23-29
    • Bertone, S.1    Schiavetti, F.2    Bellomo, R.3    Vitale, C.4    Ponte, M.5    Moretta, L.6    Mingari, M.C.7
  • 131
    • 0026532252 scopus 로고
    • Transforming growth factor-beta 1 bifunctionally regulates murine macrophages proliferation
    • Fan K., Ruan Q., Sensenbrenner L., Chen B. Transforming growth factor-beta 1 bifunctionally regulates murine macrophages proliferation. Blood. 79:1992;1679-1685.
    • (1992) Blood , vol.79 , pp. 1679-1685
    • Fan, K.1    Ruan, Q.2    Sensenbrenner, L.3    Chen, B.4
  • 132
    • 0025651251 scopus 로고
    • TGF-β regulates production of growth factors and TGF-β By human peripheral blood monocytes
    • McCartney-Francis N.L., Mizel D., Wong H., Wahl L., Wahl S.M. TGF-β regulates production of growth factors and TGF-β by human peripheral blood monocytes. Growth Factors. 4:1990;27-35.
    • (1990) Growth Factors , vol.4 , pp. 27-35
    • McCartney-Francis, N.L.1    Mizel, D.2    Wong, H.3    Wahl, L.4    Wahl, S.M.5
  • 133
  • 134
    • 0342391527 scopus 로고    scopus 로고
    • TGF-β1 promotes in vitro generation of dendritic cells by protecting progenitor cells from apoptosis
    • Riedl E., Strobl H., Majdic O., Knapp W. TGF-β1 promotes in vitro generation of dendritic cells by protecting progenitor cells from apoptosis. J. Immunol. 153:1997;L4367-4377.
    • (1997) J. Immunol. , vol.153 , pp. 4367-4377
    • Riedl, E.1    Strobl, H.2    Majdic, O.3    Knapp, W.4
  • 135
    • 0029278711 scopus 로고
    • The effects of transforming growth factor-beta and interleukins 2, 5 and 6 on immunoglobulin production in cultured rat salivary gland tissues
    • Rafferty D.E., Montgomery P.C. The effects of transforming growth factor-beta and interleukins 2, 5 and 6 on immunoglobulin production in cultured rat salivary gland tissues. Oral Microbiol. Immunol. 10:1995;81-86.
    • (1995) Oral Microbiol. Immunol. , vol.10 , pp. 81-86
    • Rafferty, D.E.1    Montgomery, P.C.2
  • 136
    • 0026662219 scopus 로고
    • Transforming growth factor-beta 1 enhances IgG and IgA sheep red blood cell responses
    • Zettel L., Clark D.A., Ernst P.B. Transforming growth factor-beta 1 enhances IgG and IgA sheep red blood cell responses. Int. Immunol. 4:1992;975-983.
    • (1992) Int. Immunol. , vol.4 , pp. 975-983
    • Zettel, L.1    Clark, D.A.2    Ernst, P.B.3
  • 138
  • 139
    • 0024989064 scopus 로고
    • Evidence for differential regulation of TGF-1 and TGF-2 expression in vivo by sandwich enzyme-linked immunosorbant assay
    • K.A. Piéz, & M.B. Sporn. Transforming growth factor, chemistry, biochemistry and therapeutics
    • Danielpour D., Kim K.Y., Dart L.L., Wanabe S., Roberts A.B., Sporn M.B. Evidence for differential regulation of TGF-1 and TGF-2 expression in vivo by sandwich enzyme-linked immunosorbant assay. Piéz K.A., Sporn M.B. Transforming growth factor, chemistry, biochemistry and therapeutics. Ann. NY Acad. Sci. 593:1990;300-302.
    • (1990) Ann. NY Acad. Sci. , vol.593 , pp. 300-302
    • Danielpour, D.1    Kim, K.Y.2    Dart, L.L.3    Wanabe, S.4    Roberts, A.B.5    Sporn, M.B.6
  • 141
    • 0029032871 scopus 로고
    • Quantitative polymerase chain reaction analysis reveals marked overexpression of interleukin-1β, interleukin-10, and interferon-γ mRNA in the lymph nodes of lupus-prone mice
    • Prud'homme G.J., Kono D.H., Theofilopoulos A.N. Quantitative polymerase chain reaction analysis reveals marked overexpression of interleukin-1β, interleukin-10, and interferon-γ mRNA in the lymph nodes of lupus-prone mice. Mol. Immunol. 32:1995;495-503.
    • (1995) Mol. Immunol. , vol.32 , pp. 495-503
    • Prud'homme, G.J.1    Kono, D.H.2    Theofilopoulos, A.N.3
  • 142
    • 0032518439 scopus 로고    scopus 로고
    • Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice
    • Balomenos D., Rumold R., Theofilopoulos A.N. Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice. J. Clin. Invest. 101:1998;364-371.
    • (1998) J. Clin. Invest. , vol.101 , pp. 364-371
    • Balomenos, D.1    Rumold, R.2    Theofilopoulos, A.N.3
  • 143
    • 0032445083 scopus 로고    scopus 로고
    • Effector and predisposing genes in murine lupus
    • Theofilopoulos A.N. Effector and predisposing genes in murine lupus. Lupus. 7:1998;575-584.
    • (1998) Lupus , vol.7 , pp. 575-584
    • Theofilopoulos, A.N.1
  • 144
    • 0031969587 scopus 로고    scopus 로고
    • IFN-gamma inhibits the production of latent transforming growth factor-beta 1 by mouse inflammatory macrophages
    • Schindler H., Diefenbach A., Rollinghoff M., Bogdan C. IFN-gamma inhibits the production of latent transforming growth factor-beta 1 by mouse inflammatory macrophages. Eur. J. Immunol. 28:1998;1181-1188.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 1181-1188
    • Schindler, H.1    Diefenbach, A.2    Rollinghoff, M.3    Bogdan, C.4
  • 145
    • 0030813880 scopus 로고    scopus 로고
    • Pathogenic lymphoid cells engineered to express TGF β1 ameliorate disease in a collagen-induced arthritis model
    • Chernajovsky Y., Adams G., Triantaphyllopoulos K., Ledda M.F., Podhajcer O.L. Pathogenic lymphoid cells engineered to express TGF β1 ameliorate disease in a collagen-induced arthritis model. Gene Therapy. 4:1997;553-559.
    • (1997) Gene Therapy , vol.4 , pp. 553-559
    • Chernajovsky, Y.1    Adams, G.2    Triantaphyllopoulos, K.3    Ledda, M.F.4    Podhajcer, O.L.5
  • 147
    • 0025729912 scopus 로고
    • Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals
    • Brandes M.E., Allen J.B., Ogawa Y., Wahl S.M. Transforming growth factor beta 1 suppresses acute and chronic arthritis in experimental animals. J. Clin. Invest. 87:1991;1108-1113.
    • (1991) J. Clin. Invest. , vol.87 , pp. 1108-1113
    • Brandes, M.E.1    Allen, J.B.2    Ogawa, Y.3    Wahl, S.M.4
  • 148
    • 0032525893 scopus 로고    scopus 로고
    • Plasmid DNA encoding transforming growth factor-β1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model
    • Song X-Y., Mili G., Jin W.W., Klinman D.M., Wahl S.M. Plasmid DNA encoding transforming growth factor-β1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model. J. Clin. Invest. 101:1998;2615-2621.
    • (1998) J. Clin. Invest. , vol.101 , pp. 2615-2621
    • Song, X.-Y.1    Mili, G.2    Jin, W.W.3    Klinman, D.M.4    Wahl, S.M.5
  • 149
    • 0025017687 scopus 로고
    • Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta
    • Allen J.B., Manthey C.L., Hand A.R., Ohura K., Ellingsworth L., Wahl S.M. Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta. J. Exp. Med. 171:1990;231-247.
    • (1990) J. Exp. Med. , vol.171 , pp. 231-247
    • Allen, J.B.1    Manthey, C.L.2    Hand, A.R.3    Ohura, K.4    Ellingsworth, L.5    Wahl, S.M.6
  • 150
    • 0029077755 scopus 로고
    • Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-β1
    • Wyss-Coray T., Feng L., Masliah E., Ruppe M.D., Lee H.S., Toggas S.M., Rockenstein E.M., Mucke L. Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-β1. Am. J. Pathol. 147:1995;53-67.
    • (1995) Am. J. Pathol. , vol.147 , pp. 53-67
    • Wyss-Coray, T.1    Feng, L.2    Masliah, E.3    Ruppe, M.D.4    Lee, H.S.5    Toggas, S.M.6    Rockenstein, E.M.7    Mucke, L.8
  • 151
    • 0026006736 scopus 로고
    • Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-β1
    • Lennart D.J., Flanders K.C., Rangers G.E., Sriram S. Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-β1. J. Immunol. 147:1991;1792-1796.
    • (1991) J. Immunol. , vol.147 , pp. 1792-1796
    • Lennart, D.J.1    Flanders, K.C.2    Rangers, G.E.3    Sriram, S.4
  • 155
    • 0028179006 scopus 로고
    • Lymphocyte responses and cytokines
    • Paul W.E., Seder R.A. Lymphocyte responses and cytokines. Cell. 76:1994;241-251.
    • (1994) Cell , vol.76 , pp. 241-251
    • Paul, W.E.1    Seder, R.A.2
  • 158
    • 0032768476 scopus 로고    scopus 로고
    • +T cells in autoimmune diabetes through the use of TCR transgenic mice
    • +T cells in autoimmune diabetes through the use of TCR transgenic mice. Immunol. Rev. 169:1999;55-65.
    • (1999) Immunol. Rev. , vol.169 , pp. 55-65
    • Suri, A.1    Katz, J.D.2
  • 159
    • 0031871335 scopus 로고    scopus 로고
    • An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus
    • Rabinovitch A. An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus. Diabetes/Metabolism Rev. 14:1998;129-151.
    • (1998) Diabetes/Metabolism Rev. , vol.14 , pp. 129-151
    • Rabinovitch, A.1
  • 160
    • 0031423760 scopus 로고    scopus 로고
    • The nonobese diabetic mouse as a model of autoimmune diabetes: Immune dysregulation gets the NOD
    • Delovitch T.L., Singh B. The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. Immunity. 7:1997;728-738.
    • (1997) Immunity , vol.7 , pp. 728-738
    • Delovitch, T.L.1    Singh, B.2
  • 161
    • 0029030964 scopus 로고
    • T helper subsets in insulin-dependent diabetes
    • Katz J.D., Benoist C., Mathis D. T helper subsets in insulin-dependent diabetes. Science. 268:1995;1185-1188.
    • (1995) Science , vol.268 , pp. 1185-1188
    • Katz, J.D.1    Benoist, C.2    Mathis, D.3
  • 162
    • 0033020168 scopus 로고    scopus 로고
    • Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein
    • Prud'homme G.J., Chang Y. Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein. Gene Therapy. 6:1999;771-777.
    • (1999) Gene Therapy , vol.6 , pp. 771-777
    • Prud'homme, G.J.1    Chang, Y.2
  • 164
    • 0030858075 scopus 로고    scopus 로고
    • Deviation of pancreas infiltrating cells to Th2 by interleukin 12 antagonists administration inhibits autoimmune diabetes
    • Trembleau S., Penna G., Gregori S., Gately M.K., Adorini L. Deviation of pancreas infiltrating cells to Th2 by interleukin 12 antagonists administration inhibits autoimmune diabetes. Eur. J. Immunol. 27:1997;2330-2339.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2330-2339
    • Trembleau, S.1    Penna, G.2    Gregori, S.3    Gately, M.K.4    Adorini, L.5
  • 165
    • 0031025193 scopus 로고    scopus 로고
    • New insights into insulin dependent diabetes mellitus from studies with transgenic mouse models
    • Grewall I.S., Flavell R.A. New insights into insulin dependent diabetes mellitus from studies with transgenic mouse models. Lab. Invest. 76:1997;3-10.
    • (1997) Lab. Invest. , vol.76 , pp. 3-10
    • Grewall, I.S.1    Flavell, R.A.2
  • 166
    • 0033222419 scopus 로고    scopus 로고
    • Intramuscular administration of expression plasmids encoding interferon-gamma-receptor/IgG1 or IL-4/IgG1 chimeric proteins protects from autoimmunity
    • Chang Y., Prud'homme G.J. Intramuscular administration of expression plasmids encoding interferon-gamma-receptor/IgG1 or IL-4/IgG1 chimeric proteins protects from autoimmunity. J. Gene Med. 1999.
    • (1999) J. Gene Med.
    • Chang, Y.1    Prud'homme, G.J.2
  • 167
    • 0030742237 scopus 로고    scopus 로고
    • T helper 2 (Th2) cells induce acute pancreatitis and diabetes in immune-compromised NOD mice
    • Pakala S.V., Kurrer M.O., Katz J.D. T helper 2 (Th2) cells induce acute
    • (1997) J. Exp. Med. , vol.186 , pp. 299-306
    • Pakala, S.V.1    Kurrer, M.O.2    Katz, J.D.3
  • 170
    • 0030175335 scopus 로고    scopus 로고
    • +suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice
    • +suppressor T cell completely prevents spontaneous autoimmune diabetes and recurrent diabetes in syngeneic islet-transplanted NOD mice. J. Autoimmun. 9:1996;331-339.
    • (1996) J. Autoimmun. , vol.9 , pp. 331-339
    • Han, H.S.1    Jun, H.S.2    Utsugi, T.3    Yoon, J.W.4
  • 171
    • 0029417193 scopus 로고
    • TGF-beta 1 overexpression in murine pancreas induces chronic pancreatitis and, together with TNF-alpha, triggers insulin-dependent diabetes
    • Sanvito F., Nichols A., Herrera P.L., Huarte J., Wohlwend A., Vassalli J.D., Orci L. TGF-beta 1 overexpression in murine pancreas induces chronic pancreatitis and, together with TNF-alpha, triggers insulin-dependent diabetes. Biochem. Biophys. Res. Comm. 26:1995;1279-1286.
    • (1995) Biochem. Biophys. Res. Comm. , vol.26 , pp. 1279-1286
    • Sanvito, F.1    Nichols, A.2    Herrera, P.L.3    Huarte, J.4    Wohlwend, A.5    Vassalli, J.D.6    Orci, L.7
  • 172
    • 0030912279 scopus 로고    scopus 로고
    • Inhibition of diabetes by an insulin-reactive CD4 T-cell clone in the nonobese diabetic mice
    • Zekzer D., Wang S.F., Wen L., Altieri M., Gurlo T., Von Grafenstein H., Sherwin R.S. Inhibition of diabetes by an insulin-reactive CD4 T-cell clone in the nonobese diabetic mice. Diabetes. 46:1997;1124-1132.
    • (1997) Diabetes , vol.46 , pp. 1124-1132
    • Zekzer, D.1    Wang, S.F.2    Wen, L.3    Altieri, M.4    Gurlo, T.5    Von Grafenstein, H.6    Sherwin, R.S.7
  • 173
    • 0028990468 scopus 로고
    • Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T cell autoimmunity in experimental allergic encephalomyelitis and multiple sclerosis
    • Olsson T. Critical influences of the cytokine orchestration on the outcome of myelin antigen-specific T cell autoimmunity in experimental allergic encephalomyelitis and multiple sclerosis. Immunol. Rev. 144:1995;245-268.
    • (1995) Immunol. Rev. , vol.144 , pp. 245-268
    • Olsson, T.1
  • 174
    • 43949160470 scopus 로고
    • Inflammatory cytokines in the brain: Does the CNS shape immune responses
    • Owens T., Renno T., Taupin V., Krakowski M. Inflammatory cytokines in the brain: does the CNS shape immune responses. Immunol. Today. 15:1994;566-571.
    • (1994) Immunol. Today , vol.15 , pp. 566-571
    • Owens, T.1    Renno, T.2    Taupin, V.3    Krakowski, M.4
  • 175
    • 0025313253 scopus 로고
    • Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity
    • Powell M.B., Mitchell D., Lederman J., Buckmeier J., Zamvil S.S., Graham M., Ruddle N.H., Steinman L. Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity. Int. Immunol. 2:1990;539-544.
    • (1990) Int. Immunol. , vol.2 , pp. 539-544
    • Powell, M.B.1    Mitchell, D.2    Lederman, J.3    Buckmeier, J.4    Zamvil, S.S.5    Graham, M.6    Ruddle, N.H.7    Steinman, L.8
  • 176
    • 0028840828 scopus 로고
    • Animal models of human disease experimental autoimmune encephalomyelitis in rodents as a model for human demyelinating disease
    • Swanborg R.H. Animal models of human disease experimental autoimmune encephalomyelitis in rodents as a model for human demyelinating disease. Clin. Immunol. Immunopathol. 77:1995;4-13.
    • (1995) Clin. Immunol. Immunopathol. , vol.77 , pp. 4-13
    • Swanborg, R.H.1
  • 178
    • 0029959963 scopus 로고    scopus 로고
    • In vivo administration of IL-4 induces TGF-β-producing cells and protects animals from experimental autoimmune encephalomyelitis
    • Inobe J.I., Chen Y., Weiner H.L. In vivo administration of IL-4 induces TGF-β-producing cells and protects animals from experimental autoimmune encephalomyelitis. Ann. NY Acad. Sci. 778:1996;390-392.
    • (1996) Ann. NY Acad. Sci. , vol.778 , pp. 390-392
    • Inobe, J.I.1    Chen, Y.2    Weiner, H.L.3
  • 180
    • 0026583488 scopus 로고
    • Evidence of endogenous regulatory function of transforming growth factor-β1 in experimental allergic encephalomyelitis
    • Racke M.K., Cannella B., Albert P., Sporn M., Raine C.S., McFarlin D.E. Evidence of endogenous regulatory function of transforming growth factor-β1 in experimental allergic encephalomyelitis. Int. Immunol. 4:1992;615-620.
    • (1992) Int. Immunol. , vol.4 , pp. 615-620
    • Racke, M.K.1    Cannella, B.2    Albert, P.3    Sporn, M.4    Raine, C.S.5    McFarlin, D.E.6
  • 181
    • 0032525044 scopus 로고    scopus 로고
    • A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice
    • Falcone M., Rajan A.J., Bloom B.R., Brosnan C.F. A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice. J. Immunol. 1998;4822-4830.
    • (1998) J. Immunol. , pp. 4822-4830
    • Falcone, M.1    Rajan, A.J.2    Bloom, B.R.3    Brosnan, C.F.4
  • 182
    • 0026542168 scopus 로고
    • Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor β after antigen-specific triggering
    • Miller A., Lider O., Roberts A.B., Sporn M.B., Weiner H.L. Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor β after antigen-specific triggering. Proc. Natl. Acad. Sci. U S A. 89:1992;421-425.
    • (1992) Proc. Natl. Acad. Sci. U S A , vol.89 , pp. 421-425
    • Miller, A.1    Lider, O.2    Roberts, A.B.3    Sporn, M.B.4    Weiner, H.L.5
  • 183
    • 0026713026 scopus 로고
    • Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, interleukin 4, and prostaglandin E expression in the brain
    • Khoury S.J., Hancock W.W., Weiner H.L. Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, interleukin 4, and prostaglandin E expression in the brain. J. Exp. Med. 176:1992;1355-1364.
    • (1992) J. Exp. Med. , vol.176 , pp. 1355-1364
    • Khoury, S.J.1    Hancock, W.W.2    Weiner, H.L.3
  • 184
    • 0028882673 scopus 로고
    • Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E
    • Hancock W.W., Polanski M., Zhang J., Blogg N., Weiner H.L. Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E. Am. J. Pathol. 147:1995;1193-1199.
    • (1995) Am. J. Pathol. , vol.147 , pp. 1193-1199
    • Hancock, W.W.1    Polanski, M.2    Zhang, J.3    Blogg, N.4    Weiner, H.L.5
  • 185
    • 0028983573 scopus 로고
    • TNFα expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis
    • Renno T., Krakowski M.K., Piccirillo C., Lin J., Owens T. TNFα expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. J. Immunol. 154:1995;944-953.
    • (1995) J. Immunol. , vol.154 , pp. 944-953
    • Renno, T.1    Krakowski, M.K.2    Piccirillo, C.3    Lin, J.4    Owens, T.5
  • 188
    • 15444341849 scopus 로고    scopus 로고
    • Cytokine gene therapy in experimental allergic encephalomyelitis by injection of plasmid DNA-cationic liposome complex into the central nervous system
    • Ludovic-Croxford J., Triantaphyllapoulos K., Podhajcer L.L., Feldmann M., Baker D., Chernajovsky Y. Cytokine gene therapy in experimental allergic encephalomyelitis by injection of plasmid DNA-cationic liposome complex into the central nervous system. J. Immunol. 160:1998;5181-5187.
    • (1998) J. Immunol. , vol.160 , pp. 5181-5187
    • Ludovic-Croxford, J.1    Triantaphyllapoulos, K.2    Podhajcer, L.L.3    Feldmann, M.4    Baker, D.5    Chernajovsky, Y.6
  • 190
    • 0032542558 scopus 로고    scopus 로고
    • Nasal administration of multiple antigens suppresses experimental autoimmune myasthenia gravis, encephalomyelitis and neuritis
    • Shi F.D., Bai X.F., Xiao B.G., van der Meide P.H., Link H. Nasal administration of multiple antigens suppresses experimental autoimmune myasthenia gravis, encephalomyelitis and neuritis. J. Neurol. Sci. 155:1998;1-12.
    • (1998) J. Neurol. Sci. , vol.155 , pp. 1-12
    • Shi, F.D.1    Bai, X.F.2    Xiao, B.G.3    Van Der Meide, P.H.4    Link, H.5
  • 191
    • 0024436509 scopus 로고
    • Transforming growth factors beta 1 and beta 2: Cytokines with identical immunosuppressive effects and a potential role in the regulation of autoimmune T cell function
    • Schluesener H.J., Lider O. Transforming growth factors beta 1 and beta 2: cytokines with identical immunosuppressive effects and a potential role in the regulation of autoimmune T cell function. J. Neuroimmunol. 24:1989;249-258.
    • (1989) J. Neuroimmunol. , vol.24 , pp. 249-258
    • Schluesener, H.J.1    Lider, O.2
  • 192
    • 0032514763 scopus 로고    scopus 로고
    • Gene therapy in allergic encephalomyelitis using myelin basic protein-specific T cells engineered to express latent transforming growth factor-beta 1
    • Chen L.Z., Hochwald G.M., Huang C., Dakin G., Tao H., Cheng C., Simmons W.J., Dranoff G., Thorbeck G.J. Gene therapy in allergic encephalomyelitis using myelin basic protein-specific T cells engineered to express latent transforming growth factor-beta 1. Proc. Natl. Acad. Sci. 95:1998;12516-12521.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 12516-12521
    • Chen, L.Z.1    Hochwald, G.M.2    Huang, C.3    Dakin, G.4    Tao, H.5    Cheng, C.6    Simmons, W.J.7    Dranoff, G.8    Thorbeck, G.J.9
  • 193
    • 0032524528 scopus 로고    scopus 로고
    • Linomide suppresses acute experimental autoimmune encephalomyelitis in Lewis rats by counteracting the imbalance of pro-inflammatory versus anti-inflammatory cytokines
    • Diab A., Michael L., Wahren B., Deng G.M., Bjork J., Hedlunk G., Zhu J. Linomide suppresses acute experimental autoimmune encephalomyelitis in Lewis rats by counteracting the imbalance of pro-inflammatory versus anti-inflammatory cytokines. J. Neuroimmunol. 85:1998;146-154.
    • (1998) J. Neuroimmunol. , vol.85 , pp. 146-154
    • Diab, A.1    Michael, L.2    Wahren, B.3    Deng, G.M.4    Bjork, J.5    Hedlunk, G.6    Zhu, J.7
  • 194
    • 0031915079 scopus 로고    scopus 로고
    • Genetic influence on disease course and cytokine response in relapsing experimental allergic encephalomyelitis
    • Kjellen P., Issazadeh S., Olsson T., Holmdahl R. Genetic influence on disease course and cytokine response in relapsing experimental allergic encephalomyelitis. Int. Immunol. 10:1998;333-340.
    • (1998) Int. Immunol. , vol.10 , pp. 333-340
    • Kjellen, P.1    Issazadeh, S.2    Olsson, T.3    Holmdahl, R.4
  • 195
    • 0031891953 scopus 로고    scopus 로고
    • Mechanisms of recovery from experimental autoimmune encephalomyelitis: T cell deletion and immune deviation in myelin basic protein T cell receptor transgenic mice
    • Chen Y., Hancock W.W., Marks R., Gonnella P., Weiner H.L. Mechanisms of recovery from experimental autoimmune encephalomyelitis: T cell deletion and immune deviation in myelin basic protein T cell receptor transgenic mice. J. Neuroimmunol. 82:1998;149-154.
    • (1998) J. Neuroimmunol. , vol.82 , pp. 149-154
    • Chen, Y.1    Hancock, W.W.2    Marks, R.3    Gonnella, P.4    Weiner, H.L.5
  • 196
    • 15444341849 scopus 로고    scopus 로고
    • Cytokine gene therapy in experimental allergic encephalomyelitis by injection of plasmid DNA-cationic liposome complex into the central nervous system
    • Croxford J.L., Triantaphyllopoulos K., Podhajcer O.L., Feldman M., Baker D., Chernajovsky Y. Cytokine gene therapy in experimental allergic encephalomyelitis by injection of plasmid DNA-cationic liposome complex into the central nervous system. J. Immunol. 160:1998;5181-5187.
    • (1998) J. Immunol. , vol.160 , pp. 5181-5187
    • Croxford, J.L.1    Triantaphyllopoulos, K.2    Podhajcer, O.L.3    Feldman, M.4    Baker, D.5    Chernajovsky, Y.6
  • 197
    • 0031808897 scopus 로고    scopus 로고
    • Altered peptide ligand modulation of experimental allergic encephalomyelitis: Immune responses within the CNS
    • Santambrogio L., Lees M.B., Sobel R.A. Altered peptide ligand modulation of experimental allergic encephalomyelitis: immune responses within the CNS. J. Neuroimmunol. 81:1998;1-13.
    • (1998) J. Neuroimmunol. , vol.81 , pp. 1-13
    • Santambrogio, L.1    Lees, M.B.2    Sobel, R.A.3
  • 198
    • 0031243563 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and transforming growth factor-beta production by isolated mononuclear cells from the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis
    • Iwashashi T., Koh C.S., Inoue A., Yanagisawa N. Tumor necrosis factor-alpha and transforming growth factor-beta production by isolated mononuclear cells from the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis. Tohoku J. Exp. Med. 183:1997;123-133.
    • (1997) Tohoku J. Exp. Med. , vol.183 , pp. 123-133
    • Iwashashi, T.1    Koh, C.S.2    Inoue, A.3    Yanagisawa, N.4
  • 199
    • 0031469731 scopus 로고    scopus 로고
    • Nasal administration of myelin basic protein prevents relapsing experimental autoimmune encephalomyelitis in DA rats by activating regulatory cells expressing IL-4 and TGF-beta mRNA
    • Bai X.F., Shi F.D., Xiao B.G., Li H.L., van der Meide P.H., Link H. Nasal administration of myelin basic protein prevents relapsing experimental autoimmune encephalomyelitis in DA rats by activating regulatory cells expressing IL-4 and TGF-beta mRNA. J. Neuroimmunol. 80:1997;65-75.
    • (1997) J. Neuroimmunol. , vol.80 , pp. 65-75
    • Bai, X.F.1    Shi, F.D.2    Xiao, B.G.3    Li, H.L.4    Van Der Meide, P.H.5    Link, H.6
  • 200
    • 0030894174 scopus 로고    scopus 로고
    • CD4 T suppressor cells mediate interferon tau protection against experimental allergic encephalomyelitis
    • Mujtaba M.G., Soos J.M., Johnson H.M. CD4 T suppressor cells mediate interferon tau protection against experimental allergic encephalomyelitis. J. Neuroimmunol. 75:1997;35-42.
    • (1997) J. Neuroimmunol. , vol.75 , pp. 35-42
    • Mujtaba, M.G.1    Soos, J.M.2    Johnson, H.M.3
  • 201
  • 202
    • 0028783962 scopus 로고
    • Staphylococcal enterotoxin B and tumor-necrosis factor-alpha-induced relapses of experimental allergic encephalomyelitis: Protection by transforming growth factor-beta and interleukin-10
    • Crisi G.M., Santambrogio L., Hochwald G.M., Smith S.R., Carlino J.A., Thorbecke G.J. Staphylococcal enterotoxin B and tumor-necrosis factor-alpha-induced relapses of experimental allergic encephalomyelitis: protection by transforming growth factor-beta and interleukin-10. Eur. J. Immunol. 25:1995;3035-3040.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 3035-3040
    • Crisi, G.M.1    Santambrogio, L.2    Hochwald, G.M.3    Smith, S.R.4    Carlino, J.A.5    Thorbecke, G.J.6
  • 203
    • 0028956025 scopus 로고
    • Interferon gamma, interleukin-4 and transforming growth factor beta in experimental autoimmune encephalomyelitis in Lewis rats: Dynamics of cellular mRNA expression in the central nervous system and lymphoid cells
    • Issazadeh S., Mustafa M., Ljungdahl A., Hojeberg B., Dagerlind A., Elde R. Interferon gamma, interleukin-4 and transforming growth factor beta in experimental autoimmune encephalomyelitis in Lewis rats: dynamics of cellular mRNA expression in the central nervous system and lymphoid cells. J. Neurosci. Res. 40:1995;579-590.
    • (1995) J. Neurosci. Res. , vol.40 , pp. 579-590
    • Issazadeh, S.1    Mustafa, M.2    Ljungdahl, A.3    Hojeberg, B.4    Dagerlind, A.5    Elde, R.6
  • 204
    • 0027941138 scopus 로고
    • Oral tolerance to myelin basic protein induces regulatory TGF-beta-secreting T cells in Peyer's patches of SJL mice
    • Santos L.M., Al-Sabbagh A., Londono A., Weiner H.L. Oral tolerance to myelin basic protein induces regulatory TGF-beta-secreting T cells in Peyer's patches of SJL mice. Cellular Immunol. 157:1994;439-447.
    • (1994) Cellular Immunol. , vol.157 , pp. 439-447
    • Santos, L.M.1    Al-Sabbagh, A.2    Londono, A.3    Weiner, H.L.4
  • 205
    • 0028178443 scopus 로고
    • Transforming growth factor-beta 1 inhibits tumor necrosis factor-alpha/lymphotoxin production and adoptive transfer of disease by effector cells of autoimmune encephalomyelitis
    • Stevens D.B., Gould K.E., Swanborg R.H. Transforming growth factor-beta 1 inhibits tumor necrosis factor-alpha/lymphotoxin production and adoptive transfer of disease by effector cells of autoimmune encephalomyelitis. J. Neuroimmunol. 51:1994;77-83.
    • (1994) J. Neuroimmunol. , vol.51 , pp. 77-83
    • Stevens, D.B.1    Gould, K.E.2    Swanborg, R.H.3
  • 206
    • 0027448605 scopus 로고
    • The major histocompatibility complex influences myelin basic protein 63-88-induced T cell cytokine profile and experimental autoimmune encephalomyelitis
    • Mustafa M., Vingsboundgahl C., Hojeberg B., Holmdahl R. The major histocompatibility complex influences myelin basic protein 63-88-induced T cell cytokine profile and experimental autoimmune encephalomyelitis. Eur. J. Immunol. 23:1993;3089-3095.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3089-3095
    • Mustafa, M.1    Vingsboundgahl, C.2    Hojeberg, B.3    Holmdahl, R.4
  • 207
    • 0027209457 scopus 로고
    • Experimental allergic encephalomyelitis: Neutralizing antibody to TGF beta 1 enhances the clinical severity of the disease
    • Johns L.D., Sriram S. Experimental allergic encephalomyelitis: neutralizing antibody to TGF beta 1 enhances the clinical severity of the disease. J. Neuroimmunol. 47:1993;1-7.
    • (1993) J. Neuroimmunol. , vol.47 , pp. 1-7
    • Johns, L.D.1    Sriram, S.2
  • 208
    • 0032126890 scopus 로고    scopus 로고
    • The pattern of cytokine gene expression in lymphoid organs and peripheral blood mononuclear cells of mice with experimental allergic encephalomyelitis
    • Okuda Y., Sakoda S., Yanagihara T. The pattern of cytokine gene expression in lymphoid organs and peripheral blood mononuclear cells of mice with experimental allergic encephalomyelitis. J. Neuroimmunol. 87:1998;147-155.
    • (1998) J. Neuroimmunol. , vol.87 , pp. 147-155
    • Okuda, Y.1    Sakoda, S.2    Yanagihara, T.3
  • 209
    • 0031639664 scopus 로고    scopus 로고
    • Oral tolerance: Mechanisms and therapy of autoimmune diseases
    • Koh D.R. Oral tolerance: mechanisms and therapy of autoimmune diseases. Ann. Acad. Sci. Singapore. 27:1998;47-53.
    • (1998) Ann. Acad. Sci. Singapore , vol.27 , pp. 47-53
    • Koh, D.R.1
  • 210
    • 0032538915 scopus 로고    scopus 로고
    • Oxazolone colitis: A murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4
    • Boirivant M., Fuss I.J., Chu A., Strober W. Oxazolone colitis: A murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4. J. Exp. Med. 188:1998;1929-1939.
    • (1998) J. Exp. Med. , vol.188 , pp. 1929-1939
    • Boirivant, M.1    Fuss, I.J.2    Chu, A.3    Strober, W.4
  • 211
    • 0031253731 scopus 로고    scopus 로고
    • TGF-beta production regulates the development of the 2,4,6-trinitrophenol-conjugated keyhole limpet hemocyanin-induced colonic inflammation in IL-2 deficient mice
    • Ludviksson B.R., Ehrhardt R.O., Strober W. TGF-beta production regulates the development of the 2,4,6-trinitrophenol-conjugated keyhole limpet hemocyanin-induced colonic inflammation in IL-2 deficient mice. J. Immunol. 159:1997;3622-3628.
    • (1997) J. Immunol. , vol.159 , pp. 3622-3628
    • Ludviksson, B.R.1    Ehrhardt, R.O.2    Strober, W.3
  • 212
    • 0031914778 scopus 로고    scopus 로고
    • Cytokines and inflammatory bowel disease
    • Rogler G., Andus T. Cytokines and inflammatory bowel disease. World J. Surg. 22:1998;383-389.
    • (1998) World J. Surg. , vol.22 , pp. 383-389
    • Rogler, G.1    Andus, T.2
  • 213
    • 0029995799 scopus 로고    scopus 로고
    • Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance
    • Neurath M.F., Fuss I., Kelsall B.L., Presky D.H., Waegell W., Strober W. Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance. J. Exp. Med. 183:1996;2605-2616.
    • (1996) J. Exp. Med. , vol.183 , pp. 2605-2616
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Presky, D.H.4    Waegell, W.5    Strober, W.6
  • 214
    • 0003116402 scopus 로고    scopus 로고
    • Organ-specific diseases
    • W.E. Paul. Philadelphia: Lippincott-Raven
    • Shevach E.M. Organ-specific diseases. Paul W.E. Fundamental immunology. 4th edn. 1999;1089-1125 Lippincott-Raven, Philadelphia.
    • (1999) Fundamental Immunology. 4th Edn. , pp. 1089-1125
    • Shevach, E.M.1
  • 215
    • 0031214341 scopus 로고    scopus 로고
    • Oral administration of the immunodominant B-chain of insulin reduces diabetes in a co-transfer model of diabetes in the NOD mouse and is associated with a switch from Th1 to Th2 cytokines
    • Polanski M., Melican N.S., Zhang J., Weiner H.L. Oral administration of the immunodominant B-chain of insulin reduces diabetes in a co-transfer model of diabetes in the NOD mouse and is associated with a switch from Th1 to Th2 cytokines. J. Autoimmun. 10:1997;339-346.
    • (1997) J. Autoimmun. , vol.10 , pp. 339-346
    • Polanski, M.1    Melican, N.S.2    Zhang, J.3    Weiner, H.L.4
  • 216
    • 0028685851 scopus 로고
    • Prevention of diabetes in BB/Wor rats by injection of peritoneal exudate cells cultured in the presence of transforming growth factor beta (TGF-beta) and islet cells
    • Koevary S.B. Prevention of diabetes in BB/Wor rats by injection of peritoneal exudate cells cultured in the presence of transforming growth factor beta (TGF-beta) and islet cells. Diabetes Res. 27:1994;1-14.
    • (1994) Diabetes Res. , vol.27 , pp. 1-14
    • Koevary, S.B.1
  • 217
    • 0031924980 scopus 로고    scopus 로고
    • Oral administration of schistosome egg antigens and insulin B-chain generates and enhances Th2-type responses in NOD mice
    • Maron R., Palanivel V., Weiner H.L., Harn D.A. Oral administration of schistosome egg antigens and insulin B-chain generates and enhances Th2-type responses in NOD mice. Clin. Immunol. Immunopathol. 87:1998;85-92.
    • (1998) Clin. Immunol. Immunopathol. , vol.87 , pp. 85-92
    • Maron, R.1    Palanivel, V.2    Weiner, H.L.3    Harn, D.A.4
  • 218
    • 0031171607 scopus 로고    scopus 로고
    • Molecular role of TGF-β, secreted by a new type of CD4+suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice
    • Han H.S., Jun H.S., Utsugi T., Yoon J.W. Molecular role of TGF-β, secreted by a new type of CD4+suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice. J. Autoimmun. 10:1997;299-307.
    • (1997) J. Autoimmun. , vol.10 , pp. 299-307
    • Han, H.S.1    Jun, H.S.2    Utsugi, T.3    Yoon, J.W.4
  • 220
    • 0032400510 scopus 로고    scopus 로고
    • Decrease of LFA-1 is associated with upregulation of TGF-beta in CD4(+) T cell clones derived from rats nasally tolerized against experimental autoimmune myasthenia gravis
    • Xiao B.G., Zhang G.X., Shi F.D., Ma C.G., Link H. Decrease of LFA-1 is associated with upregulation of TGF-beta in CD4(+) T cell clones derived from rats nasally tolerized against experimental autoimmune myasthenia gravis. Clin. Immunol. Immunopathol. 89:1998;196-204.
    • (1998) Clin. Immunol. Immunopathol. , vol.89 , pp. 196-204
    • Xiao, B.G.1    Zhang, G.X.2    Shi, F.D.3    Ma, C.G.4    Link, H.5
  • 221
    • 0029915770 scopus 로고    scopus 로고
    • Mucosal tolerance to experimental autoimmune myasthenia gravis is associated with down-regulation of AChR-specific IFN-gamma-expressing Th1-like cells and up-regulation of TGF-beta mRNA in mononuclear cells
    • Ma C.G., Zhang G.X., Xiao B.G., Wang Z.Y., Link J., Olssor T., Link H. Mucosal tolerance to experimental autoimmune myasthenia gravis is associated with down-regulation of AChR-specific IFN-gamma-expressing Th1-like cells and up-regulation of TGF-beta mRNA in mononuclear cells. Ann. NY Acad. Sci. 778:1996;273-287.
    • (1996) Ann. NY Acad. Sci. , vol.778 , pp. 273-287
    • Ma, C.G.1    Zhang, G.X.2    Xiao, B.G.3    Wang, Z.Y.4    Link, J.5    Olssor, T.6    Link, H.7
  • 222
    • 0031029275 scopus 로고    scopus 로고
    • Effect of transforming growth factor beta-1 in endotoxin- induced uveitis
    • Peng B., Li Q., Roberge F.G., Chan C.C. Effect of transforming growth factor beta-1 in endotoxin- induced uveitis. Invest. Opthal. Vis. Sci. 38:1997;257-260.
    • (1997) Invest. Opthal. Vis. Sci. , vol.38 , pp. 257-260
    • Peng, B.1    Li, Q.2    Roberge, F.G.3    Chan, C.C.4
  • 223
    • 0032525893 scopus 로고    scopus 로고
    • Plasmid DNA encoding transforming growth factor-beta 1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model
    • Song X.Y., Gu M., Jin W.W., Klinman D.M., Wahl S.M. Plasmid DNA encoding transforming growth factor-beta 1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model. J. Clin. Invest. 101:1998;2615-2621.
    • (1998) J. Clin. Invest. , vol.101 , pp. 2615-2621
    • Song, X.Y.1    Gu, M.2    Jin, W.W.3    Klinman, D.M.4    Wahl, S.M.5
  • 224
    • 0032403567 scopus 로고    scopus 로고
    • Oral Delivery of group A streptococcal cell walls augments circulating TGF-beta and suppresses streptococcal cell wall arthritis
    • Chen W., Jin W., Cook M., Weiner H.L., Wahl S.M. Oral Delivery of group A streptococcal cell walls augments circulating TGF-beta and suppresses streptococcal cell wall arthritis. J. Immunol. 161:1998;6297-6304.
    • (1998) J. Immunol. , vol.161 , pp. 6297-6304
    • Chen, W.1    Jin, W.2    Cook, M.3    Weiner, H.L.4    Wahl, S.M.5
  • 226
    • 0031926223 scopus 로고    scopus 로고
    • The relevance of transforming growth factor-beta 1 in pulmonary disease after injury from radiation therapy
    • Anscher M.S., Kong F.M., Jirtle R.L. The relevance of transforming growth factor-beta 1 in pulmonary disease after injury from radiation therapy. Lung Cancer. 19:1998;109-120.
    • (1998) Lung Cancer , vol.19 , pp. 109-120
    • Anscher, M.S.1    Kong, F.M.2    Jirtle, R.L.3
  • 227
    • 0029837675 scopus 로고    scopus 로고
    • Cytokines and pulmonary fibrosis
    • Zhang K., Phan S.H. Cytokines and pulmonary fibrosis. Biol. Sig. 5:1996;232-239.
    • (1996) Biol. Sig. , vol.5 , pp. 232-239
    • Zhang, K.1    Phan, S.H.2
  • 228
    • 0032515145 scopus 로고    scopus 로고
    • Role of urokinase in the activation of macrophage-associated TGF-beta in silica-induced lung fibrosis
    • Matrat M., Lardot C., Huaux F., Broeckaert F., Lison D. Role of urokinase in the activation of macrophage-associated TGF-beta in silica-induced lung fibrosis. J. Toxicol. Environ. Health. 55:1998;359-371.
    • (1998) J. Toxicol. Environ. Health. , vol.55 , pp. 359-371
    • Matrat, M.1    Lardot, C.2    Huaux, F.3    Broeckaert, F.4    Lison, D.5
  • 229
    • 0031602567 scopus 로고    scopus 로고
    • Differential effects of cyclosporin A and tacrolimus on the production of TGF-beta: Implications for the development of obliterative bronchiolitis after lung transplantation
    • Talbot D., Dark J.H., Kirby J.A. Differential effects of cyclosporin A and tacrolimus on the production of TGF-beta: implications for the development of obliterative bronchiolitis after lung transplantation. Transplant International. 11:1998;S325-S327.
    • (1998) Transplant International , vol.11
    • Talbot, D.1    Dark, J.H.2    Kirby, J.A.3
  • 231
    • 0030891040 scopus 로고    scopus 로고
    • TGF-beta and glomerulonephritis: Anti-inflammatory versus prosclerotic actions
    • Kitamura M., Suto T.S. TGF-beta and glomerulonephritis: anti-inflammatory versus prosclerotic actions. Nephrol. Dial. Transplan. 12:1997;669-679.
    • (1997) Nephrol. Dial. Transplan. , vol.12 , pp. 669-679
    • Kitamura, M.1    Suto, T.S.2
  • 232
    • 0033556556 scopus 로고    scopus 로고
    • Serum transforming growth factor-beta 1 levels in bone marrow transplant recipients correlate with blood cell counts and chronic graft-versus-host disease
    • Liem L.M., Fibbe W.E., van Houwelingen H.C., Goulmy E. Serum transforming growth factor-beta 1 levels in bone marrow transplant recipients correlate with blood cell counts and chronic graft-versus-host disease. Transplantation. 67:1999;59-65.
    • (1999) Transplantation , vol.67 , pp. 59-65
    • Liem, L.M.1    Fibbe, W.E.2    Van Houwelingen, H.C.3    Goulmy, E.4
  • 234
    • 0030630914 scopus 로고    scopus 로고
    • Cytokines and cytokine therapies in HIV infection
    • Valdez H., Lederman M.M. Cytokines and cytokine therapies in HIV infection. AIDS Clinical Review. 1:1997-98;187-228.
    • (1997) AIDS Clinical Review , vol.1 , pp. 187-228
    • Valdez, H.1    Lederman, M.M.2
  • 235
    • 0031821875 scopus 로고    scopus 로고
    • +immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • +immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:1998;287-296.
    • (1998) J. Exp. Med. , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2


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