Transforming growth factor-βs: A multifunctional cytokine family

Hormone Research in Paediatrics

Volumn 45, Issue 3-5, 1996, Pages 222-226

  Chobaz, Edmond M ^a   Souchelnitskiy, Sergiy ^a   Pellerin, Sylvie ^a   Defaye, Geneviève ^a   Cochet, Claude ^a   Feige, Jean Jacques ^a  

^a CEA GRENOBLE   (France)

Author keywords

Adrenocortical cell; Cell differentiation; Embryogenesis; Steroidogenesis; Thrombospondins; Transforming growth factors

Indexed keywords

CORTICOTROPIN; THROMBOSPONDIN; TRANSFORMING GROWTH FACTOR BETA; CARRIER PROTEIN; CYTOKINE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ADRENAL CORTEX CELL; ADRENAL CORTEX FUNCTION; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CELL TYPE; CONFERENCE PAPER; EMBRYO DEVELOPMENT; EXTRACELLULAR MATRIX; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN STRUCTURE; STEROIDOGENESIS; ADRENAL CORTEX; ANIMAL; CYTOLOGY; HUMAN; PHYSIOLOGY; REVIEW;

ADRENAL CORTEX; ANIMALS; CARRIER PROTEINS; CYTOKINES; HUMANS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029665787     PISSN: 16632818     EISSN: 16632826     Source Type: Journal    
DOI: 10.1159/000184792     Document Type: Article

References (21)

1. Roberts AB, Anzano MA, Lamb LC, Smith JM, Sporn MB: New class of transforming growth factors potentiated by epidermal growth factor. Proc Natl Acad Sei USA 1981: 78:5339-5343.
2. Roberts AB, Sporn MB: The transforming growth factor-ßs; in Peptide Growth Factors and Their Receptors. Berlin, Springer, 1990, pp 419-472.
3. Dcrvnk R, Jarrett Ja, Chen EY, Eaton DH, Bell JR, Assoian RK, Roberts AB, Sporn MB, Goeddel DV: Human transforming growth fac-tor-beta cDNA sequence and expression in tumor ccll lines. Nature 1985;316:701-705.
4. Burt D W, Law AS: Evolution of the transforming growth factor-beta superfamily. Prog Growth Factor Res 1994:5::99-118.
5. Kingsley DM: The TGF-ß superfamily: New members, new receptors, and new genetic tests of function in different organisms. Genes Dev 1994:8:133-146.
6. Letterio JJ, Geiser AG, Kulkarni AB, Roche NS, Sporn MB, Roberts AB: Maternal rescue of transforming growth lactor-ßi null mice. Science 1994:264:1936-1938.
7. Jhappan C, Geiser AG, Kordon EC, Baghcri D, Henninghausen L, Roberts AB, Smith GH, Merlino G: Targeting expression of a transforming growth factor-ß, transgenc to the pregnant mammary gland inhibits alveolar development and lactation. EMBO J 1993:12:1835-1845.
8. Grainger DJ, Kemp R, Liu AC, Lawn RM, Metcalfe JC: Activation of transforming growth factor-ß is inhibited in transgenic apoli-poprotcin (a) mice. Nature 1994:370:460-462.
9. Wrana JL, Attisano L, Wiescr R, Ventura F, Massague J: Mechanism of activation of the TGF-ß receptor. Nature 1994:370:341-345.
10. Andres JL, Stanley K, C'heifctz S, Massague J: Membrane-anchored and soluble forms of beta-glycan. a polymorphic proteoglycan that binds transforming growth factor-ß. J Cell Biol 1989;109:3137-3145.
11. McAllister KA, Grogg KM. Johnson DW, Gal-lione CJ, Baldwin MA, Jackson CE, Helmbold EA, Markel DS, McKinnon WC, Murrell J, McCormick MK, Pericak-Vance MA, Heutink P, Oostra BA, Haitjema T, Westcrman CJJ, Portcous ME, Guttmacher AE, Letarte M, Marchuk DA: Endoglin, a TGF-ß binding protein of endothelial cells, is the gene for hereditary hacmorrhagic telangiectasia type I. Nat Genet 1994;8:345-351.
12. Border WA, Noble NA, Yamamoto T, Harper JR, Yamaguchi Y, Pierschbacher MD, Ruos-lahti E: Natural inhibitor of transforming grow th factor-ß protects against scarring in experimental kidney disease. Nature 1992:360: 361-364.
13. Streuli CH, Schmidhauser C, Kobrin M, Bissell MJ, Derynck R: Extracellular matrix regulates expression of the TGF-ßi gene. J Cell Biol 1993;120:253-260.
14. Schultz-Cherrv S, Lawler J, Murphy-Ullrich JE: The type I repeats of thrombospondin I activate latent transforming growth factor-ß. J Biol Chem 1994:269:26783-26788.
15. Schultz-Cherry S, Ribeiro S, Gentry L, Murphy-Ullrich JE: Thrombospondin binds and activates the small and large forms of latent transforming growth factor ß in a chemically defined system. J Biol Chem 1994:269:26775-26782.
16. Feige JJ, Cochet C, Rainey WE, Madani C, C'hambaz EM: Tvpeß transforming growth factor affects adrenocortical cell-differentiated functions. J Biol Chem 1987:262:13491-13495.
17. Perrin A, Pascal O, Defay G, Feige JJ, Cham-baz EM: Transforming growth factor-beta is a negative regulator of adrenocortical steroid 17-alpha-hydroxylase gene expression. Endocrinology 1991:128:357-362.
18. Cochet C, Feige JJ, Chambaz EM: Bovine adrenocortical cells exhibit high affinity TGF-ß receptors which are regulated by adrenocorti-cotropin. J Biol Chem 1988;263:5707-5713.
19. Souchelnitskiy S, Chambaz EM, Feige JJ: Thrombospondins selectively activate one of the two latent forms of TGF-ß present in adrenocortical cell conditioned medium. Endocrinology 1995:136:5118-5126.
20. Pellerin S, Lafeuilladc B, Wade RH, Savona C, Chambaz EM, Feige JJ: The molecular structure of corticotropin-induced secreted protein, a novel member of the thrombospondin family. J Biol Chem 1993;268:18810-18817.
21. Pellerin S, Ifeuillade B, Scherrer N, Gagnon J, Shi DL, Chambaz EM, Feige JJ: Corticotro-pin-induced secreted protein, an ACTH-in-duccd protein sccreted by adrenocortical cells is structurally related to thrombospondins. J Biol Chem 1993:268:4304-4310.