-
1
-
-
0031437374
-
Co-receptor and accessory regulation of B-cell antigen receptor signal transduction
-
Buhl AM, Cambier JC. Co-receptor and accessory regulation of B-cell antigen receptor signal transduction. Immunol Rev 1997; 160: 127-138.
-
(1997)
Immunol Rev
, vol.160
, pp. 127-138
-
-
Buhl, A.M.1
Cambier, J.C.2
-
2
-
-
0031897046
-
Positive versus negative signaling by lymphocyte antigen receptors
-
Healy JI, Goodnow CC. Positive versus negative signaling by lymphocyte antigen receptors. Annu Rev Immunol 1998; 16: 645-670.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 645-670
-
-
Healy, J.I.1
Goodnow, C.C.2
-
3
-
-
0028784215
-
Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease
-
Hibbs ML et al. Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease. Cell 1995; 83: 301-311.
-
(1995)
Cell
, vol.83
, pp. 301-311
-
-
Hibbs, M.L.1
-
4
-
-
0030740148
-
Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation
-
Chan VW et al. Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation. Immunity 1997; 7: 69-81.
-
(1997)
Immunity
, vol.7
, pp. 69-81
-
-
Chan, V.W.1
-
5
-
-
0028806216
-
Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice
-
Nishizumi H et al. Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice. Immunity 1995; 3: 549-560.
-
(1995)
Immunity
, vol.3
, pp. 549-560
-
-
Nishizumi, H.1
-
7
-
-
0027197067
-
Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene
-
Shultz LD et al. Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell 1993; 73: 1445-1454.
-
(1993)
Cell
, vol.73
, pp. 1445-1454
-
-
Shultz, L.D.1
-
8
-
-
0027195626
-
Motheaten and viable motheaten mice have mutations in the hematopoeitic cell phosphatase gene
-
Tsui HW, Siminovitch KA, deSouza L, Tsui FWL. Motheaten and viable motheaten mice have mutations in the hematopoeitic cell phosphatase gene. Nat Genet 1993; 4: 124-129.
-
(1993)
Nat Genet
, vol.4
, pp. 124-129
-
-
Tsui, H.W.1
Siminovitch, K.A.2
DeSouza, L.3
Tsui, F.W.L.4
-
9
-
-
0032550365
-
A double-edged kinase Lyn: A positive and negative regulator for antigen receptor-mediated signals
-
Nishizumi H, Horikawa K, Mlinaric-Rascan I, Yamamoto T. A double-edged kinase Lyn: a positive and negative regulator for antigen receptor-mediated signals. J Exp Med 1998; 187: 1343-1348.
-
(1998)
J Exp Med
, vol.187
, pp. 1343-1348
-
-
Nishizumi, H.1
Horikawa, K.2
Mlinaric-Rascan, I.3
Yamamoto, T.4
-
10
-
-
0032055828
-
Polygenic autoimmune traits: Lyn, CD22 and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection
-
Cornall RJ et al. Polygenic autoimmune traits: Lyn, CD22 and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection. Immunity 1998; 8: 497-508.
-
(1998)
Immunity
, vol.8
, pp. 497-508
-
-
Cornall, R.J.1
-
11
-
-
0032492994
-
Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes
-
Chan VW, Lowell CA, DeFranco AL. Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes. Curr Biol 1998; 8: 545-553.
-
(1998)
Curr Biol
, vol.8
, pp. 545-553
-
-
Chan, V.W.1
Lowell, C.A.2
DeFranco, A.L.3
-
12
-
-
0032524987
-
Affinity maturation in Lyn kinase-deficient mice with defective germinal center formation
-
Kato J et al. Affinity maturation in Lyn kinase-deficient mice with defective germinal center formation. J Immunol 1998; 160: 4788-4795.
-
(1998)
J Immunol
, vol.160
, pp. 4788-4795
-
-
Kato, J.1
-
13
-
-
0031080328
-
CD22 is a negative regulator of B-cell receptor signalling
-
Nitschke L et al. CD22 is a negative regulator of B-cell receptor signalling. Curr Biol 1997; 7: 133-143.
-
(1997)
Curr Biol
, vol.7
, pp. 133-143
-
-
Nitschke, L.1
-
14
-
-
0030993376
-
CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling
-
Tedder TF, Tuscano J, Sato S, Kehrl JH. CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. Annu Rev Immunol 1997; 15: 481-504.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 481-504
-
-
Tedder, T.F.1
Tuscano, J.2
Sato, S.3
Kehrl, J.H.4
-
15
-
-
0030062935
-
B and T cells are not required for the viable motheaten phenotype
-
Yu CC et al. B and T cells are not required for the viable motheaten phenotype. J Exp Med 1996; 183: 371-380.
-
(1996)
J Exp Med
, vol.183
, pp. 371-380
-
-
Yu, C.C.1
-
16
-
-
0032473487
-
Inhibition of the B cell by CD22: A requirement for Lyn
-
Smith KGC et al. Inhibition of the B cell by CD22: a requirement for Lyn. J Exp Med 1998; 187: 807-811.
-
(1998)
J Exp Med
, vol.187
, pp. 807-811
-
-
Smith, K.G.C.1
-
17
-
-
0029838991
-
Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice
-
Wang J. Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice. J Exp Med 1996; 184: 831-838.
-
(1996)
J Exp Med
, vol.184
, pp. 831-838
-
-
Wang, J.1
-
18
-
-
0030924380
-
Inhibitory receptors abound?
-
Cambier JC. Inhibitory receptors abound? Proc Natl Acad Sci USA 1997; 94: 5993-5995.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5993-5995
-
-
Cambier, J.C.1
-
19
-
-
0030770336
-
Negative signaling in B cells: SHIP Grbs Shc
-
Tridandapani S et al. Negative signaling in B cells: SHIP Grbs Shc. Immunol Today 1997; 18: 424-427.
-
(1997)
Immunol Today
, vol.18
, pp. 424-427
-
-
Tridandapani, S.1
-
20
-
-
0344936020
-
Inhibitory signaling by B cell Fc gamma RIIb
-
Coggeshall KM. Inhibitory signaling by B cell Fc gamma RIIb. Curr Opin Immunol 1998; 10: 306-312.
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 306-312
-
-
Coggeshall, K.M.1
-
21
-
-
0028932411
-
Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc-gamma RIIB1
-
D'Ambrosio D et al. Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc-gamma RIIB1. Science 1995; 268: 293-297.
-
(1995)
Science
, vol.268
, pp. 293-297
-
-
D'Ambrosio, D.1
-
22
-
-
0030792093
-
Protein-tyrosine phosphatase SHP-1 is dispensable for Fc gamma RIIB-mediated inhibition of B cell antigen receptor activation
-
Nadler MJS et al. Protein-tyrosine phosphatase SHP-1 is dispensable for Fc gamma RIIB-mediated inhibition of B cell antigen receptor activation. J Biol Chem 1997; 272: 20038-20043.
-
(1997)
J Biol Chem
, vol.272
, pp. 20038-20043
-
-
Nadler, M.J.S.1
-
23
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol EA et al. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995; 3: 541-547.
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
-
25
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse P et al. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 1995; 270: 985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
-
26
-
-
0031154577
-
CTLA-4 Ig prevents lymphoproliferative and fatal multiorgan tissue destruction in CTLA-4-deficient mice
-
Tivol EA et al. CTLA-4 Ig prevents lymphoproliferative and fatal multiorgan tissue destruction in CTLA-4-deficient mice. J Immunol 1997; 158: 5091-5094.
-
(1997)
J Immunol
, vol.158
, pp. 5091-5094
-
-
Tivol, E.A.1
-
27
-
-
16044369031
-
A pathogenetic role for TNFα in the syndrome of cachexia, arthritis and autoimmunity resulting from tristetraprolin (TTP) deficiency
-
Taylor GA et al. A pathogenetic role for TNFα in the syndrome of cachexia, arthritis and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity 1996; 4: 445-454.
-
(1996)
Immunity
, vol.4
, pp. 445-454
-
-
Taylor, G.A.1
-
28
-
-
0030882906
-
Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/ macrophage progenitors may be responsible for TNFalpha overproduction
-
Carballo E, Gilkeson GS, Blackshear PJ. Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/ macrophage progenitors may be responsible for TNFalpha overproduction. J Clin Invest 1997; 100: 986-995.
-
(1997)
J Clin Invest
, vol.100
, pp. 986-995
-
-
Carballo, E.1
Gilkeson, G.S.2
Blackshear, P.J.3
-
29
-
-
0028990699
-
SLE-like autoantibodies and Sjogren's syndrome-like lymphoproliferation in TGF-beta knockout mice
-
Dang H et al. SLE-like autoantibodies and Sjogren's syndrome-like lymphoproliferation in TGF-beta knockout mice. J Immunol 1995; 155: 3205-3212.
-
(1995)
J Immunol
, vol.155
, pp. 3205-3212
-
-
Dang, H.1
-
30
-
-
0028783963
-
+ T cells
-
+ T cells. Eur J Immunol 1995; 25: 3053-3059.
-
(1995)
Eur J Immunol
, vol.25
, pp. 3053-3059
-
-
Sadlack, B.1
-
31
-
-
0028784289
-
Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment
-
Willerford DM et al. Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment. Immunity 1995; 3: 521-530.
-
(1995)
Immunity
, vol.3
, pp. 521-530
-
-
Willerford, D.M.1
-
32
-
-
0029028363
-
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor β
-
Suzuki H et al. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor β. Science 1995; 268: 1472-1476.
-
(1995)
Science
, vol.268
, pp. 1472-1476
-
-
Suzuki, H.1
-
33
-
-
0031569514
-
Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor
-
van Parijs L et al. Functional responses and apoptosis of CD25 (IL-2R alpha)-deficient T cells expressing a transgenic antigen receptor. J Immunol 1997; 158: 3738-3745.
-
(1997)
J Immunol
, vol.158
, pp. 3738-3745
-
-
Van Parijs, L.1
-
34
-
-
17544398702
-
Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis
-
Refaeli Y et al. Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. Immunity 1998; 8: 615-623.
-
(1998)
Immunity
, vol.8
, pp. 615-623
-
-
Refaeli, Y.1
-
35
-
-
0029944667
-
Enhanced and accelerated lymphoproliferation in Fas-null mice
-
Adachi M et al. Enhanced and accelerated lymphoproliferation in Fas-null mice. Proc Natl Acad Sci USA 1996; 93: 2131-2136.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2131-2136
-
-
Adachi, M.1
-
37
-
-
0031778836
-
Homozygous C1q deficiency caused glomerulonephritis associated with multiple apoptotic bodies
-
Botto M et al. Homozygous C1q deficiency caused glomerulonephritis associated with multiple apoptotic bodies. Nat Genet 1998; 19: 56-59.
-
(1998)
Nat Genet
, vol.19
, pp. 56-59
-
-
Botto, M.1
-
38
-
-
0031776409
-
The lupus paradox
-
Carroll MC. The lupus paradox. Nat Genet 1998; 19: 3-4.
-
(1998)
Nat Genet
, vol.19
, pp. 3-4
-
-
Carroll, M.C.1
-
39
-
-
0031921084
-
The role of complement and complement receptors in induction and regulation of immunity
-
Carroll MC. The role of complement and complement receptors in induction and regulation of immunity. Annu Rev Immunol 1998; 16: 545-568.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 545-568
-
-
Carroll, M.C.1
-
40
-
-
0032101037
-
T cell-dependent immune response in C1q-deficient mice: Defective interferon gamma production by antigen-specific T cells
-
Cutler AJ et al. T cell-dependent immune response in C1q-deficient mice: defective interferon gamma production by antigen-specific T cells. J Exp Med 1998; 187: 1789-1797.
-
(1998)
J Exp Med
, vol.187
, pp. 1789-1797
-
-
Cutler, A.J.1
-
41
-
-
0032489921
-
Activated complement component 3 (C3) is required for ultraviolet induction of immunosuppression and antigenic tolerance
-
Hammerberg C, Katiyar SK, Carroll MC, Cooper KD. Activated complement component 3 (C3) is required for ultraviolet induction of immunosuppression and antigenic tolerance. J Exp Med 1998; 187: 1133-1138.
-
(1998)
J Exp Med
, vol.187
, pp. 1133-1138
-
-
Hammerberg, C.1
Katiyar, S.K.2
Carroll, M.C.3
Cooper, K.D.4
-
42
-
-
0025939204
-
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease
-
Strasser A et al. Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease. Proc Natl Acad Sci USA 1991; 88: 8661-8665.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 8661-8665
-
-
Strasser, A.1
-
43
-
-
0024521441
-
bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation
-
McDonnell TJ et al. bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation. Cell 1989; 57: 79-88.
-
(1989)
Cell
, vol.57
, pp. 79-88
-
-
McDonnell, T.J.1
-
44
-
-
0026468231
-
Differential effects of Bcl-2 on T and B cells in transgenic mice
-
Katsumata M et al. Differential effects of Bcl-2 on T and B cells in transgenic mice. Proc Natl Acad Sci USA 1998; 89: 11376-11380.
-
(1998)
Proc Natl Acad Sci USA
, vol.89
, pp. 11376-11380
-
-
Katsumata, M.1
-
45
-
-
0029956023
-
Constitutive expression of bcl-2 in B cells causes a lethal form of lupus-like autoimmune disease after induction of neonatal tolerance to H-2b alloantigens
-
Lopez-Hoyos M et al. Constitutive expression of bcl-2 in B cells causes a lethal form of lupus-like autoimmune disease after induction of neonatal tolerance to H-2b alloantigens. J Exp Med 1996; 183: 2523-2531.
-
(1996)
J Exp Med
, vol.183
, pp. 2523-2531
-
-
Lopez-Hoyos, M.1
-
46
-
-
0027260581
-
The bcl-2 gene product inhibits clonal deletion of self-reactive B lymphocytes in the periphery but not in the bone marrow
-
Nisitani S et al. The bcl-2 gene product inhibits clonal deletion of self-reactive B lymphocytes in the periphery but not in the bone marrow. J Exp Med 1993; 178: 1247-1254.
-
(1993)
J Exp Med
, vol.178
, pp. 1247-1254
-
-
Nisitani, S.1
-
47
-
-
0027447188
-
Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
-
Hartley SB et al. Elimination of self-reactive B lymphocytes proceeds in two stages: arrested development and cell death. Cell 1993; 72: 325-335.
-
(1993)
Cell
, vol.72
, pp. 325-335
-
-
Hartley, S.B.1
-
48
-
-
0030694311
-
Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen-dependent manner and promotes receptor editing in autoreactive, immature B cells
-
Lang J et al. Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen-dependent manner and promotes receptor editing in autoreactive, immature B cells. J Exp Med 1997; 186: 1513-1522.
-
(1997)
J Exp Med
, vol.186
, pp. 1513-1522
-
-
Lang, J.1
-
49
-
-
0032006177
-
Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development
-
Hande S, Notidis E, Manser T. Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development. Immunity 1998; 8: 189-198.
-
(1998)
Immunity
, vol.8
, pp. 189-198
-
-
Hande, S.1
Notidis, E.2
Manser, T.3
-
50
-
-
0032033419
-
Cytokines induce the development of functionally heterogeneous T helper cell subsets
-
O'Garra A. Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity 1998; 8: 275-283.
-
(1998)
Immunity
, vol.8
, pp. 275-283
-
-
O'Garra, A.1
-
51
-
-
0030702821
-
Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis
-
Seery JP, Carroll JM, Cattell V, Watt FM. Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis. J Exp Med 1997; 186: 1451-1459.
-
(1997)
J Exp Med
, vol.186
, pp. 1451-1459
-
-
Seery, J.P.1
Carroll, J.M.2
Cattell, V.3
Watt, F.M.4
-
52
-
-
1842417145
-
Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice
-
Erb KJ et al. Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice. J Exp Med 1997; 852: 329-339.
-
(1997)
J Exp Med
, vol.852
, pp. 329-339
-
-
Erb, K.J.1
-
53
-
-
0025736362
-
Major histocompatibility complex class II hyperexpression on B cells in interleukin 4-transgenic mice does not lead to B cell proliferation and hypergammaglobulinemia
-
Muller W, Kuhn R, Rajewsky K. Major histocompatibility complex class II hyperexpression on B cells in interleukin 4-transgenic mice does not lead to B cell proliferation and hypergammaglobulinemia. Eur J Immunol 1991; 21: 921-925.
-
(1991)
Eur J Immunol
, vol.21
, pp. 921-925
-
-
Muller, W.1
Kuhn, R.2
Rajewsky, K.3
-
54
-
-
0026074762
-
Interleukin 4 expressed in situ selective alters thymocyte development
-
Lewis DB et al. Interleukin 4 expressed in situ selective alters thymocyte development. J Exp Med 1991; 173: 89-100.
-
(1991)
J Exp Med
, vol.173
, pp. 89-100
-
-
Lewis, D.B.1
-
55
-
-
0000397436
-
Murine lupus models: Gene-specific and genome-wide studies
-
Lahita RG (ed.) Academic Press: San Diego, (in press)
-
Theofilopoulos AN, Kono DH. Murine lupus models: gene-specific and genome-wide studies. In: Lahita RG (ed.) Systeme Lupus Erythematosus 3rd edition. Academic Press: San Diego, 1998 (in press).
-
(1998)
Systeme Lupus Erythematosus 3rd Edition
-
-
Theofilopoulos, A.N.1
Kono, D.H.2
-
56
-
-
0030901968
-
The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity
-
Tedder TF, Inaoki M, Sato S. The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity. Immunity 1997; 6: 107-118.
-
(1997)
Immunity
, vol.6
, pp. 107-118
-
-
Tedder, T.F.1
Inaoki, M.2
Sato, S.3
-
57
-
-
0030588569
-
CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity
-
Sato S et al. CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity. J Immunol 1996; 157: 4371-4378.
-
(1996)
J Immunol
, vol.157
, pp. 4371-4378
-
-
Sato, S.1
-
58
-
-
0030784484
-
CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes
-
Inaoki M et al. CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. J Exp Med 1997; 186: 1923-1931.
-
(1997)
J Exp Med
, vol.186
, pp. 1923-1931
-
-
Inaoki, M.1
-
59
-
-
0028876127
-
An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes
-
Zhang L et al. An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes. Mol Cell Biol 1995; 15: 6961-6970.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 6961-6970
-
-
Zhang, L.1
-
60
-
-
0031571332
-
Intercellular adhesion molecule-1 deficiency protects MRL/MpJ-Fas (lpr) mice from early lethality
-
Bullard DC et al. Intercellular adhesion molecule-1 deficiency protects MRL/MpJ-Fas (lpr) mice from early lethality. J Immunol 1997; 159: 2058-2067.
-
(1997)
J Immunol
, vol.159
, pp. 2058-2067
-
-
Bullard, D.C.1
-
61
-
-
0030983935
-
Intercellular adhesion molecule-1 deficiency protects MRL/MpJ-Fas (lpr) mice from early lethality
-
Lloyd CM. Intercellular adhesion molecule-1 deficiency protects MRL/MpJ-Fas (lpr) mice from early lethality. J Clin Invest 1997; 100: 963-967.
-
(1997)
J Clin Invest
, vol.100
, pp. 963-967
-
-
Lloyd, C.M.1
-
62
-
-
0030878992
-
Clinical and serologic manifestations of autoimmune disease in MRL-lpr/lpr mice lacking nitric oxide synthase type 2
-
Gilkeson GS et al. Clinical and serologic manifestations of autoimmune disease in MRL-lpr/lpr mice lacking nitric oxide synthase type 2. J Exp Med 1997; 186: 365-373.
-
(1997)
J Exp Med
, vol.186
, pp. 365-373
-
-
Gilkeson, G.S.1
-
63
-
-
0028036257
-
G-monomethyl-L-arginine
-
G-monomethyl-L-arginine. J Exp Med 1994; 179: 651-660.
-
(1994)
J Exp Med
, vol.179
, pp. 651-660
-
-
Weinberg, J.B.1
-
64
-
-
0031127933
-
Effect of late modulation of nitric oxide production on murine lupus
-
Oates JC et al. Effect of late modulation of nitric oxide production on murine lupus. Clin Immunol Immunopathol 1997; 83: 86-92.
-
(1997)
Clin Immunol Immunopathol
, vol.83
, pp. 86-92
-
-
Oates, J.C.1
-
65
-
-
0028326095
-
Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice
-
Jevnikar AN, Grusby MJ, Glimcher LH. Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice. J Exp Med 1994; 179: 1137-1143.
-
(1994)
J Exp Med
, vol.179
, pp. 1137-1143
-
-
Jevnikar, A.N.1
Grusby, M.J.2
Glimcher, L.H.3
-
66
-
-
0029086120
-
Murine lupus in MRL/lpr mice lacking CD4 or CD8 T cells
-
Koh DR et al. Murine lupus in MRL/lpr mice lacking CD4 or CD8 T cells. Eur J Immunol 1995; 25: 2558-2562.
-
(1995)
Eur J Immunol
, vol.25
, pp. 2558-2562
-
-
Koh, D.R.1
-
67
-
-
0028898599
-
Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I
-
Maldonado MA et al. Greatly reduced lymphoproliferation in lpr mice lacking major histocompatibility complex class I. J Exp Med 1995; 181: 641-649.
-
(1995)
J Exp Med
, vol.181
, pp. 641-649
-
-
Maldonado, M.A.1
-
68
-
-
0029070099
-
+ double-negative T cells as the predominant population in enlarged lymph nodes
-
+ double-negative T cells as the predominant population in enlarged lymph nodes. J Immunol 1995; 154: 4986-4995.
-
(1995)
J Immunol
, vol.154
, pp. 4986-4995
-
-
Giese, T.1
Davidson, W.F.2
-
69
-
-
0028985378
-
+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules
-
+ T cells but normal autoantibody production in lpr/lpr mice lacking major histocompatibility complex class I molecules. Eur J Immunol 1995; 25: 37-41.
-
(1995)
Eur J Immunol
, vol.25
, pp. 37-41
-
-
Ohteki, T.1
Iwamoto, M.2
Izui, S.3
MacDonald, H.R.4
-
70
-
-
0029665432
-
2-Microglobulin dependence of the lupus-like autoimmune syndrome of MKL-lpr mice
-
2-Microglobulin dependence of the lupus-like autoimmune syndrome of MKL-lpr mice. J Immunol 1996; 156: 4932-4939.
-
(1996)
J Immunol
, vol.156
, pp. 4932-4939
-
-
Christianson, G.J.1
-
71
-
-
0027242279
-
Selection of the T cell receptor repertoire in lpr mice
-
Herron LR et al. Selection of the T cell receptor repertoire in lpr mice. J Immunol 1993; 151: 3450-3459.
-
(1993)
J Immunol
, vol.151
, pp. 3450-3459
-
-
Herron, L.R.1
-
72
-
-
0028268517
-
Chronic treatment of C3H-lpr/lpr and C3H-gld/gld mice with anti-CD8 monoclonal antibody prevents the accumulation of double-negative T cells but not autoantibody production
-
Giese T, Davidson WF. Chronic treatment of C3H-lpr/lpr and C3H-gld/gld mice with anti-CD8 monoclonal antibody prevents the accumulation of double-negative T cells but not autoantibody production. J Immunol 1994; 152: 2000-2010.
-
(1994)
J Immunol
, vol.152
, pp. 2000-2010
-
-
Giese, T.1
Davidson, W.F.2
-
73
-
-
0031092710
-
Alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity
-
Peng SL et al. Alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity. J Immunol 1997 158: 2464-2470.
-
(1997)
J Immunol
, vol.158
, pp. 2464-2470
-
-
Peng, S.L.1
-
74
-
-
0028483990
-
Treatment of murine lupus with CTLA-4Ig
-
Finck BK, Linsley PS, Wofsy D. Treatment of murine lupus with CTLA-4Ig. Science 1994; 265: 1225-1227.
-
(1994)
Science
, vol.265
, pp. 1225-1227
-
-
Finck, B.K.1
Linsley, P.S.2
Wofsy, D.3
-
75
-
-
0030039652
-
+ cell subset shifts and autoimmunity in the BXSB mouse by murine CTLA-4Ig
-
+ cell subset shifts and autoimmunity in the BXSB mouse by murine CTLA-4Ig. J Immunol 1996; 156: 1262-1268.
-
(1996)
J Immunol
, vol.156
, pp. 1262-1268
-
-
Chu, E.B.1
-
76
-
-
0028834366
-
Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule
-
Nakajima A et al. Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule. Eur J Immunol 1995; 25: 3060-3069.
-
(1995)
Eur J Immunol
, vol.25
, pp. 3060-3069
-
-
Nakajima, A.1
-
77
-
-
0028852328
-
Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
-
Mohan C, Shi Y, Laman JD, Datta SK. Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J Immunol 1995; 154: 1470-1480.
-
(1995)
J Immunol
, vol.154
, pp. 1470-1480
-
-
Mohan, C.1
Shi, Y.2
Laman, J.D.3
Datta, S.K.4
-
78
-
-
0031253956
-
Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways
-
Daikh DI et al. Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways. J Immunol 1997; 159: 3104-3108.
-
(1997)
J Immunol
, vol.159
, pp. 3104-3108
-
-
Daikh, D.I.1
-
79
-
-
0029968324
-
Murine lupus in the absence of αβ T cells
-
Peng SL et al. Murine lupus in the absence of αβ T cells. J Immunol 1996; 156: 4041-4049.
-
(1996)
J Immunol
, vol.156
, pp. 4041-4049
-
-
Peng, S.L.1
-
80
-
-
0030589323
-
Propagation and regulation of systemic autoimmunity by gamma delta T cells
-
Peng SL, Madaio MP, Hayday AC, Craft J. Propagation and regulation of systemic autoimmunity by gamma delta T cells. J Immunol 1996; 157: 5689-5698.
-
(1996)
J Immunol
, vol.157
, pp. 5689-5698
-
-
Peng, S.L.1
Madaio, M.P.2
Hayday, A.C.3
Craft, J.4
-
81
-
-
0030425799
-
T cells in murine lupus: Propagation and regulation of disease
-
Peng SL, Craft J. T cells in murine lupus: propagation and regulation of disease. Mol Biol Rep 1996; 23: 247-251.
-
(1996)
Mol Biol Rep
, vol.23
, pp. 247-251
-
-
Peng, S.L.1
Craft, J.2
-
82
-
-
0031974934
-
Perform protects against autoimmunity in lupus-prone mice
-
Peng SL Moslehi J, Robert ME, Craft J. Perform protects against autoimmunity in lupus-prone mice. J Immunol 1998; 160: 652-660.
-
(1998)
J Immunol
, vol.160
, pp. 652-660
-
-
Peng, S.L.1
Moslehi, J.2
Robert, M.E.3
Craft, J.4
-
83
-
-
0027983579
-
The role of B cells in lpr/lpr-induced autoimmunity
-
Shlomchik MJ et al. The role of B cells in lpr/lpr-induced autoimmunity. J Exp Med 1994; 180: 1295-1306.
-
(1994)
J Exp Med
, vol.180
, pp. 1295-1306
-
-
Shlomchik, M.J.1
-
86
-
-
0030953632
-
Roles of interferon-gamma and interleukin-4 in murine lupus
-
Peng SL, Moslehi J, Craft J. Roles of interferon-gamma and interleukin-4 in murine lupus. J Clin Invest 1997; 99: 1936-1946.
-
(1997)
J Clin Invest
, vol.99
, pp. 1936-1946
-
-
Peng, S.L.1
Moslehi, J.2
Craft, J.3
-
87
-
-
0032518439
-
Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice
-
Balomenos D, Rumold R, Theofilopoulos AN. Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice. J Clin Invest 1998; 101: 364-371.
-
(1998)
J Clin Invest
, vol.101
, pp. 364-371
-
-
Balomenos, D.1
Rumold, R.2
Theofilopoulos, A.N.3
-
88
-
-
0031155269
-
IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/lpr mice
-
Haas C, Ryffel B, LeHir M. IFN-gamma is essential for the development of autoimmune glomerulonephritis in MRL/lpr mice. J Immunol 1997; 158: 5485-5491.
-
(1997)
J Immunol
, vol.158
, pp. 5485-5491
-
-
Haas, C.1
Ryffel, B.2
LeHir, M.3
-
90
-
-
0032522778
-
IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB × NZW)F1 mice
-
Haas C, Ryffel B, LeHir M. IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB × NZW)F1 mice. J Immunol 1998; 160: 3713-3718.
-
(1998)
J Immunol
, vol.160
, pp. 3713-3718
-
-
Haas, C.1
Ryffel, B.2
LeHir, M.3
-
91
-
-
0032512855
-
Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis
-
Clynes R, Dumitru C, Ravetch JV. Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. Science 1998; 279: 1052-1054.
-
(1998)
Science
, vol.279
, pp. 1052-1054
-
-
Clynes, R.1
Dumitru, C.2
Ravetch, J.V.3
-
92
-
-
0031036084
-
Interleukin-l protects against a genetically linked lupus-like autoimmune syndrome
-
Santiago M-L et al. Interleukin-l protects against a genetically linked lupus-like autoimmune syndrome. J Exp Med 1997; 185: 65-70.
-
(1997)
J Exp Med
, vol.185
, pp. 65-70
-
-
Santiago, M.-L.1
-
93
-
-
0031446643
-
Role of the major histocompatibility complex class II Ea gene in lupus susceptibility in mice
-
Ibnou-Zekri N et al. Role of the major histocompatibility complex class II Ea gene in lupus susceptibility in mice. Proc Natl Acad Sci USA 1997; 94: 14654-14659.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14654-14659
-
-
Ibnou-Zekri, N.1
-
95
-
-
0030892234
-
Apoptosis by death factor
-
Nagata S. Apoptosis by death factor. Cell 1997; 88: 355-365.
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
96
-
-
0024209920
-
Deletion of potentially self-reactive T cell receptor specificities in L3T4, Lyt-2 cells of lpr mice
-
Kotzin BL, Babcock SK, Herron LR. Deletion of potentially self-reactive T cell receptor specificities in L3T4, Lyt-2 cells of lpr mice. J Exp Med 1988; 168: 2221-2229.
-
(1988)
J Exp Med
, vol.168
, pp. 2221-2229
-
-
Kotzin, B.L.1
Babcock, S.K.2
Herron, L.R.3
-
97
-
-
0024331976
-
+ and abnormal lpr and gld cell populations
-
+ and abnormal lpr and gld cell populations. J Exp Med 1989; 170: 1869-1877.
-
(1989)
J Exp Med
, vol.170
, pp. 1869-1877
-
-
Singer, P.A.1
-
98
-
-
0026531128
-
Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of lpr and gld mutant mice
-
Sidman CL, Marshall JD, VonBoehmer H. Transgenic T cell receptor interactions in the lymphoproliferative and autoimmune syndromes of lpr and gld mutant mice. Eur J Immunol 1992; 22: 499-504.
-
(1992)
Eur J Immunol
, vol.22
, pp. 499-504
-
-
Sidman, C.L.1
Marshall, J.D.2
VonBoehmer, H.3
-
99
-
-
0028485743
-
The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
-
Singer GG, Abbas AK. The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1994; 1: 365-371.
-
(1994)
Immunity
, vol.1
, pp. 365-371
-
-
Singer, G.G.1
Abbas, A.K.2
-
100
-
-
0030200829
-
The roles of Fas/APO-1 (CD95) ad TNF in antigen-induced programmed cell death in T cell receptor transgenic mice
-
Sytwu H-K, Liblau RS, McDevitt HO. The roles of Fas/APO-1 (CD95) ad TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. Immunity 1996; 5: 17-30.
-
(1996)
Immunity
, vol.5
, pp. 17-30
-
-
Sytwu, H.-K.1
Liblau, R.S.2
McDevitt, H.O.3
-
101
-
-
0027314703
-
Mature T-cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide
-
Russell JH, Rush B, Weaver C, Wang RD. Mature T-cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc Natl Acad Sci USA 1993; 90: 4409-4413.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4409-4413
-
-
Russell, J.H.1
Rush, B.2
Weaver, C.3
Wang, R.D.4
-
102
-
-
0029097729
-
Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo
-
Mogil RJ et al. Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo. Int Immunol 1995; 7: 1451-1458.
-
(1995)
Int Immunol
, vol.7
, pp. 1451-1458
-
-
Mogil, R.J.1
-
103
-
-
0029076561
-
+ T cells
-
+ T cells. Nature 1995; 376: 181-184.
-
(1995)
Nature
, vol.376
, pp. 181-184
-
-
Rathmell, J.C.1
-
104
-
-
0030592564
-
Expansion or elimination of B cells in vivo: Dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor
-
Rathmell JC et al. Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 1996; 87: 319-329.
-
(1996)
Cell
, vol.87
, pp. 319-329
-
-
Rathmell, J.C.1
-
105
-
-
0028931042
-
Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus
-
Roark JH et al. Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus. J Exp Med 1995; 181: 1157-1167.
-
(1995)
J Exp Med
, vol.181
, pp. 1157-1167
-
-
Roark, J.H.1
-
106
-
-
0032494194
-
Efficient peripheral clonal elimination of B lymphocytes in MRL/lpr mice bearing autoantibody transgenes
-
Kench JA, Russell DM, Nemazee D Efficient peripheral clonal elimination of B lymphocytes in MRL/lpr mice bearing autoantibody transgenes. J Exp Med 1998; 188: 909-917.
-
(1998)
J Exp Med
, vol.188
, pp. 909-917
-
-
Kench, J.A.1
Russell, D.M.2
Nemazee, D.3
-
108
-
-
0028445340
-
Polygenic control of susceptibility to murine systemic lupus erythematosus
-
Morel L et al. Polygenic control of susceptibility to murine systemic lupus erythematosus. Immunity 1994; 1: 219-229.
-
(1994)
Immunity
, vol.1
, pp. 219-229
-
-
Morel, L.1
-
109
-
-
0027985199
-
Lupus susceptibility loci in New Zealand mice
-
Kono DH et al. Lupus susceptibility loci in New Zealand mice. Proc Natl Acad Sci USA 1994; 91: 10168-10172.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10168-10172
-
-
Kono, D.H.1
-
110
-
-
0028942144
-
Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner
-
Drake CG et al. Analysis of the New Zealand Black contribution to lupus-like renal disease. Multiple genes that operate in a threshold manner. J Immunol 1995; 154: 2441-2445.
-
(1995)
J Immunol
, vol.154
, pp. 2441-2445
-
-
Drake, C.G.1
-
111
-
-
0030587115
-
Backcross analysis of genes linked to autoantibody production in New Zealand white mice
-
Vyse TJ et al. Backcross analysis of genes linked to autoantibody production in New Zealand white mice. J Immunol 1996; 157: 2719-2722.
-
(1996)
J Immunol
, vol.157
, pp. 2719-2722
-
-
Vyse, T.J.1
-
112
-
-
0030478149
-
Effect of genetic background on the contribution of New Zealand black loci to autoimmune lupus nephritis
-
Rozzo SJ, Vyse TJ, Drake CG, Kotzin BL. Effect of genetic background on the contribution of New Zealand black loci to autoimmune lupus nephritis. Proc Natl Acad Sci USA 1996; 93: 15164-15169.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 15164-15169
-
-
Rozzo, S.J.1
Vyse, T.J.2
Drake, C.G.3
Kotzin, B.L.4
-
113
-
-
0031157347
-
Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand Black mice
-
Vyse TJ et al. Control of multiple autoantibodies linked with a lupus nephritis susceptibility locus in New Zealand Black mice. J Immunol 1997; 158: 5566-5570.
-
(1997)
J Immunol
, vol.158
, pp. 5566-5570
-
-
Vyse, T.J.1
-
114
-
-
0031179651
-
Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity
-
Mohan C, Morel L, Yang P, Wakeland EK. Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity. J Immunol 1997; 159: 454-460.
-
(1997)
J Immunol
, vol.159
, pp. 454-460
-
-
Mohan, C.1
Morel, L.2
Yang, P.3
Wakeland, E.K.4
-
115
-
-
0032520923
-
Genetic dissection of SLE pathogenesis
-
Mohan C et al. Genetic dissection of SLE pathogenesis. J Clin Invest 1998; 101: 1362-1372.
-
(1998)
J Clin Invest
, vol.101
, pp. 1362-1372
-
-
Mohan, C.1
-
116
-
-
0026471742
-
Genetic analysis of MRL-lpr mice: Relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci
-
Watson ML et al. Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. J Exp Med 1992; 176: 1645-1656.
-
(1992)
J Exp Med
, vol.176
, pp. 1645-1656
-
-
Watson, M.L.1
-
117
-
-
0030708809
-
Host modifier genes affect mouse autoimmunity induced by the lpr gene
-
Wang Y et al. Host modifier genes affect mouse autoimmunity induced by the lpr gene. Am J Pathol 1997; 151: 1791-1794.
-
(1997)
Am J Pathol
, vol.151
, pp. 1791-1794
-
-
Wang, Y.1
|