-
1
-
-
0029429522
-
Dry cleaning, some chlorinated solvents and other industrial chemicals. Chloral and chloral hydrate
-
IARC. Dry Cleaning, Some Chlorinated Solvents and other Industrial Chemicals. Chloral and Chloral Hydrate. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. 63:4-17; 33-221; 245-268 (1995).
-
(1995)
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
, vol.63
, pp. 4-17
-
-
-
4
-
-
0000060569
-
Proposed guidelines for carcinogen risk assessment; notice
-
U.S. Environmental Protection Agency: Proposed Guidelines for Carcinogen Risk Assessment; Notice. Fed Reg 61:17960-10811 (1996).
-
(1996)
Fed Reg
, vol.61
, pp. 17960-110811
-
-
-
6
-
-
0023963070
-
Surface water supplies and health
-
Craun GF. Surface water supplies and health. J Am Water Works Assoc 80:40-52 (1988).
-
(1988)
J Am Water Works Assoc
, vol.80
, pp. 40-52
-
-
Craun, G.F.1
-
7
-
-
0033919417
-
Metabolism of trichloroethylene
-
Lash LH. Metabolism of trichloroethylene. Environ Health Perspect 108(suppl 2):177-200 (2000).
-
(2000)
Environ Health Perspect
, vol.108
, Issue.SUPPL. 2
, pp. 177-200
-
-
Lash, L.H.1
-
8
-
-
0033945538
-
Modes of action of trichloroethylene for kidney tumorigenesis
-
Lash LH. Modes of action of trichloroethylene for kidney tumorigenesis. Environ Health Perspect 108(suppl 2):225-240 (2000).
-
(2000)
Environ Health Perspect
, vol.108
, Issue.SUPPL. 2
, pp. 225-240
-
-
Lash, L.H.1
-
9
-
-
85033504675
-
Trichloroethylene-induced mouse lung tumors: Studies of the mode of action and comparisons between species
-
Green T, Mainwaring GW, Foster JR. Trichloroethylene-induced mouse lung tumors: studies of the mode of action and comparisons between species. Fundam Appl Toxicol 37:125-130 (1997).
-
(1997)
Fundam Appl Toxicol
, vol.37
, pp. 125-130
-
-
Green, T.1
Mainwaring, G.W.2
Foster, J.R.3
-
10
-
-
0004328487
-
-
NCI-CG-TR-2. Bethesda, MD:National Cancer Institute
-
NCI. Carcinogenesis Bioassay of Trichloroethylene. NCI-CG-TR-2. Bethesda, MD:National Cancer Institute, 1976.
-
(1976)
Carcinogenesis Bioassay of Trichloroethylene
-
-
-
12
-
-
0003089789
-
Experimental research on trichloroethylene carcinogenesis
-
(Maltoni G, Mehlman MA, eds). Princeton, NJ:Princeton Scientific
-
Maltoni C, Lefemine G, Cotti G. Experimental research on trichloroethylene carcinogenesis. In: Archives of Research on Industrial Carcinogenesis (Maltoni G, Mehlman MA, eds). Princeton, NJ:Princeton Scientific, 1986.
-
(1986)
Archives of Research on Industrial Carcinogenesis
-
-
Maltoni, C.1
Lefemine, G.2
Cotti, G.3
-
14
-
-
0018840773
-
Carcinogenicity study of trichloroethylene by longterm inhalation in three animal species
-
Henschler D, Romen W, Elsasser HM, Reichert D, Eder E, Radwan Z. Carcinogenicity study of trichloroethylene by longterm inhalation in three animal species. Arch Toxicol 43:237-248 (1980).
-
(1980)
Arch Toxicol
, vol.43
, pp. 237-248
-
-
Henschler, D.1
Romen, W.2
Elsasser, H.M.3
Reichert, D.4
Eder, E.5
Radwan, Z.6
-
15
-
-
0021141224
-
Carcinogenicity study of trichloroethylene, with and without epoxide stabilizers, in mice
-
Henschler D, Elsasser H, Romen H, Eder E. Carcinogenicity study of trichloroethylene, with and without epoxide stabilizers, in mice. J Cancer Res Clin Oncol 107:149-156 (1984).
-
(1984)
J Cancer Res Clin Oncol
, vol.107
, pp. 149-156
-
-
Henschler, D.1
Elsasser, H.2
Romen, H.3
Eder, E.4
-
16
-
-
0021067936
-
Inhalation carcinogenicity of trichloroethylene in mice and rats
-
Fukuda K, Takemoto K, Tsuruta H. Inhalation carcinogenicity of trichloroethylene in mice and rats. Ind Health 21:243-254 (1983).
-
(1983)
Ind Health
, vol.21
, pp. 243-254
-
-
Fukuda, K.1
Takemoto, K.2
Tsuruta, H.3
-
17
-
-
0030052417
-
Cancer in relation to occupational exposure to trichloroethylene
-
Weiss NS. Cancer in relation to occupational exposure to trichloroethylene. Occup Environ Med 53:1-5 (1996).
-
(1996)
Occup Environ Med
, vol.53
, pp. 1-5
-
-
Weiss, N.S.1
-
18
-
-
0025882787
-
Retrospective cohort study of workers at an aircraft maintenance facility. I: Epidemiological results
-
Spirtas R, Stewart PA, Lee JS, Marano DE, Forbes CD, Grauman DJ, Pettigrew HM, Blair A, Hoover RN, Cohen JL. Retrospective cohort study of workers at an aircraft maintenance facility. I: Epidemiological results. Br J Ind Med 48:515-530 (1991).
-
(1991)
Br J Ind Med
, vol.48
, pp. 515-530
-
-
Spirtas, R.1
Stewart, P.A.2
Lee, J.S.3
Marano, D.E.4
Forbes, C.D.5
Grauman, D.J.6
Pettigrew, H.M.7
Blair, A.8
Hoover, R.N.9
Cohen, J.L.10
-
19
-
-
0028344623
-
Updated and expanded Swedish cohort study of trichloroethylene and cancer risk
-
Axelson O, Selden A, Andersson K, Hogstedt C. Updated and expanded Swedish cohort study of trichloroethylene and cancer risk. J Occup Med 36:556-562 (1995).
-
(1995)
J Occup Med
, vol.36
, pp. 556-562
-
-
Axelson, O.1
Selden, A.2
Andersson, K.3
Hogstedt, C.4
-
20
-
-
0029075402
-
Cancer incidence among Finnish workers exposed to halogenated hydrocarbons
-
Anttila A, Pukkala E, Sallmen M, Hernberg S, Hemminki K. Cancer incidence among Finnish workers exposed to halogenated hydrocarbons. J Occup Med 37:797-806 (1995).
-
(1995)
J Occup Med
, vol.37
, pp. 797-806
-
-
Anttila, A.1
Pukkala, E.2
Sallmen, M.3
Hernberg, S.4
Hemminki, K.5
-
22
-
-
0024394728
-
Genetic toxicology of 1,1,2-trichloroethylene
-
Crebelli R, Carere A. Genetic toxicology of 1,1,2-trichloroethylene. Mutat Res 221:11-37 (1989).
-
(1989)
Mutat Res
, vol.221
, pp. 11-37
-
-
Crebelli, R.1
Carere, A.2
-
23
-
-
13844323013
-
Genetic toxicology of trichloroethylene (TCE)
-
Fahrig R, Madle S, Baumann H. Genetic toxicology of trichloroethylene (TCE). Mutat Res 340:1-36 (1995).
-
(1995)
Mutat Res
, vol.340
, pp. 1-36
-
-
Fahrig, R.1
Madle, S.2
Baumann, H.3
-
24
-
-
0033932461
-
Mutagenicity of trichloroethylene and its metabolites: Implications for the risk assessment of trichloroethylene
-
Moore M, Harrington-Brock K. Mutagenicity of trichloroethylene and its metabolites: implications for the risk assessment of trichloroethylene. Environ Health Perspect 108(suppl 2):215-223 (2000).
-
(2000)
Environ Health Perspect
, vol.108
, Issue.SUPPL. 2
, pp. 215-223
-
-
Moore, M.1
Harrington-Brock, K.2
-
25
-
-
0022372389
-
Induction of hepatic cell proliferation and unscheduled DNA synthesis in mouse hepatocytes following in vivo treatment
-
Mirsalis JC, Tyson CK, Loh EN, Steinmetz KL, Bakke JP, Hamilton CM, Spak DK, Spalding JW. Induction of hepatic cell proliferation and unscheduled DNA synthesis in mouse hepatocytes following in vivo treatment. Carcinogenesis 6:1521-1524 (1985).
-
(1985)
Carcinogenesis
, vol.6
, pp. 1521-1524
-
-
Mirsalis, J.C.1
Tyson, C.K.2
Loh, E.N.3
Steinmetz, K.L.4
Bakke, J.P.5
Hamilton, C.M.6
Spak, D.K.7
Spalding, J.W.8
-
26
-
-
0023233965
-
The in vivo, in vitro hepatocyte assay for assessing DNA repair and DNA replication studies in the CD-1 mouse
-
Doolittle DJ, Muller G, Scribner HE. The in vivo, in vitro hepatocyte assay for assessing DNA repair and DNA replication studies in the CD-1 mouse. Food Chem Toxicicol 25:399-405 (1987).
-
(1987)
Food Chem Toxicicol
, vol.25
, pp. 399-405
-
-
Doolittle, D.J.1
Muller, G.2
Scribner, H.E.3
-
27
-
-
0024455271
-
Measurement of unscheduled DNA synthesis and S-phase synthesis in rodent hepatocytes following in vivo treatment: Testing of 24 compounds
-
Mirsalis JC, Tyson CK, Steinmetz KL, Loh EK, Hamilton CM, Bakke JP, Spalding JW. Measurement of unscheduled DNA synthesis and S-phase synthesis in rodent hepatocytes following in vivo treatment: testing of 24 compounds. Environ Mol Mutagen 14:155-164 (1989).
-
(1989)
Environ Mol Mutagen
, vol.14
, pp. 155-164
-
-
Mirsalis, J.C.1
Tyson, C.K.2
Steinmetz, K.L.3
Loh, E.K.4
Hamilton, C.M.5
Bakke, J.P.6
Spalding, J.W.7
-
28
-
-
0022538708
-
Induction of single strand breaks in DNA of mice by trichloroethylene and tetrachloroethylene
-
Walles SAS. Induction of single strand breaks in DNA of mice by trichloroethylene and tetrachloroethylene. Toxicol Lett 31:31-35 (1986).
-
(1986)
Toxicol Lett
, vol.31
, pp. 31-35
-
-
Walles, S.A.S.1
-
29
-
-
0023887960
-
Induction of strand breaks in DNA by trichloroethylene and metabolites in rat and mouse liver in vivo
-
Nelson MA, Bull RJ. Induction of strand breaks in DNA by trichloroethylene and metabolites in rat and mouse liver in vivo. Toxicol Appl Pharmacol 94:45-54 (1988).
-
(1988)
Toxicol Appl Pharmacol
, vol.94
, pp. 45-54
-
-
Nelson, M.A.1
Bull, R.J.2
-
30
-
-
0020059408
-
The pharmacokinetics and macromolecular interactions of trichloroethylene in mice and rats
-
Stott WT, Quast JF, Watanabe PG. The pharmacokinetics and macromolecular interactions of trichloroethylene in mice and rats. Toxicol Appl Pharmacol 62:137-151 (1982).
-
(1982)
Toxicol Appl Pharmacol
, vol.62
, pp. 137-151
-
-
Stott, W.T.1
Quast, J.F.2
Watanabe, P.G.3
-
31
-
-
0020002153
-
2 and interaction of a metabolite with liver DNA in rats and mice
-
2 and interaction of a metabolite with liver DNA in rats and mice. J Toxicol Environ Health 9:797-813 (1982).
-
(1982)
J Toxicol Environ Health
, vol.9
, pp. 797-813
-
-
Parchman, L.G.1
Magee, P.N.2
-
32
-
-
0021081798
-
Interactions of trichloroethylene with DNA in vitro and with RNA and DNA of various mouse tissues in vivo
-
Bergman K. Interactions of trichloroethylene with DNA in vitro and with RNA and DNA of various mouse tissues in vivo. Arch Toxicol 54:181-193 (1983).
-
(1983)
Arch Toxicol
, vol.54
, pp. 181-193
-
-
Bergman, K.1
-
33
-
-
77957180793
-
Adduction of hemoglobin and albumin in vivo by metabolites of trichloroethylene, trichloroacetate and dichloroacetate in rats and mice
-
Stevens DK, Eyre RJ, Bull RJ. Adduction of hemoglobin and albumin in vivo by metabolites of trichloroethylene, trichloroacetate and dichloroacetate in rats and mice. Fundam Appl Toxicol 19:336-342 (1992).
-
(1992)
Fundam Appl Toxicol
, vol.19
, pp. 336-342
-
-
Stevens, D.K.1
Eyre, R.J.2
Bull, R.J.3
-
34
-
-
0029609146
-
Acid-labile adducts to protein can be used as indicators of the cysteine S-conjugate pathway of trichloroethene metabolism
-
Eyre RJ, Stevens DK, Parker JC, Bull RJ. Acid-labile adducts to protein can be used as indicators of the cysteine S-conjugate pathway of trichloroethene metabolism. J Toxicol Environ Health 46:443-464 (1995).
-
(1995)
J Toxicol Environ Health
, vol.46
, pp. 443-464
-
-
Eyre, R.J.1
Stevens, D.K.2
Parker, J.C.3
Bull, R.J.4
-
35
-
-
0030714940
-
Dose-dependent binding of trichloroethylene to hepatic DNA and protein at low doses in mice
-
Kautianen A, Vogel JS, Turteltaub KW. Dose-dependent binding of trichloroethylene to hepatic DNA and protein at low doses in mice. Chem-Biol Interact 106:109-121 (1999).
-
(1999)
Chem-biol Interact
, vol.106
, pp. 109-121
-
-
Kautianen, A.1
Vogel, J.S.2
Turteltaub, K.W.3
-
37
-
-
0032846843
-
Oxidative stress and DNA damage in Fischer rats following acute exposure to trichlorothylene or perchloroethylene
-
Toraason M, Clark J, Dankovic D, Mathias P, Skaggs S, Walker C, Werren D. Oxidative stress and DNA damage in Fischer rats following acute exposure to trichlorothylene or perchloroethylene. Toxicology 138:43-53 (1999).
-
(1999)
Toxicology
, vol.138
, pp. 43-53
-
-
Toraason, M.1
Clark, J.2
Dankovic, D.3
Mathias, P.4
Skaggs, S.5
Walker, C.6
Werren, D.7
-
39
-
-
0021964203
-
Prooxidant states and tumor promotion
-
Cerutti P. Prooxidant states and tumor promotion. Science 227:375-381 (1985).
-
(1985)
Science
, vol.227
, pp. 375-381
-
-
Cerutti, P.1
-
40
-
-
0027960682
-
ras Proto-oncogene activation in dichloroacetic-, trichloroethylene-and tetrachloroethylene-induced liver tumors in B6C3F1 mice
-
Anna CH, Maronpot RR, Pereira MA, Foley JF, Malarkey DE, Anderson MW. ras Proto-oncogene activation in dichloroacetic-, trichloroethylene-and tetrachloroethylene-induced liver tumors in B6C3F1 mice. Carcinogenesis 15:2255-2261 (1994).
-
(1994)
Carcinogenesis
, vol.15
, pp. 2255-2261
-
-
Anna, Ch.1
Maronpot, R.R.2
Pereira, Ma.3
Foley, J.F.4
Malarkey, D.E.5
Anderson, M.W.6
-
41
-
-
0023217707
-
Activated oncogenes in B6C3F1 mouse liver tumors: Implications for risk assessment
-
Reynolds SH, Stowers SJ, Patterson RM, Maronpot RR, Aaronson SA, Anderson MW. Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment. Science 237:1309-1316 (1987).
-
(1987)
Science
, vol.237
, pp. 1309-1316
-
-
Reynolds, S.H.1
Stowers, S.J.2
Patterson, R.M.3
Maronpot, R.R.4
Aaronson, S.A.5
Anderson, M.W.6
-
42
-
-
0029098336
-
Mutations in the ras proto-oncogene: Clues to etiology and molecular pathogenesis of mouse liver tumors
-
Maronpot RR, Fox T, Malarkey DE, Goldsworthy TL. Mutations in the ras proto-oncogene: clues to etiology and molecular pathogenesis of mouse liver tumors. Toxicology 101:125-156 (1995).
-
(1995)
Toxicology
, vol.101
, pp. 125-156
-
-
Maronpot, R.R.1
Fox, T.2
Malarkey, D.E.3
Goldsworthy, T.L.4
-
43
-
-
0028933539
-
Ras oncogene activation during hepatocarcinogenesis in B6C3F1 male mice by dichloroacetic and trichloroacetic acids
-
Ferreira-Gonzalez A, DeAngelo AB, Nasim S, Garrett CT. Ras oncogene activation during hepatocarcinogenesis in B6C3F1 male mice by dichloroacetic and trichloroacetic acids. Carcinogenesis 16:495-500 (1995).
-
(1995)
Carcinogenesis
, vol.16
, pp. 495-500
-
-
Ferreira-Gonzalez, A.1
DeAngelo, A.B.2
Nasim, S.3
Garrett, C.T.4
-
44
-
-
0343994566
-
Effects of trichloroacetate (TCA) and dichloroacetate (DCA) on H-ras in male B6C3F1 mice
-
Orner GA, Malone JA, Stillwell LC, Cheng RS, Stauber AJ, Sasser LB, Thrall BD, Bull RJ. Effects of trichloroacetate (TCA) and dichloroacetate (DCA) on H-ras in male B6C3F1 mice. Toxicologist 42:60 (1998).
-
(1998)
Toxicologist
, vol.42
, pp. 60
-
-
Orner, G.A.1
Malone, J.A.2
Stillwell, L.C.3
Cheng, R.S.4
Stauber, A.J.5
Sasser, L.B.6
Thrall, B.D.7
Bull, R.J.8
-
45
-
-
0031594817
-
p21 (Ras) downstream effectors are increased in activity or expression in mouse liver tumors but do not differ between RAS-mutated and RAS-wild-type lesions
-
Kalkuhl A, Troppmair J, Buchmann A, Stinchcombe S, Buenemann CL, Rapp UR, Kaestner K, Schwarz M. p21 (Ras) downstream effectors are increased in activity or expression in mouse liver tumors but do not differ between RAS-mutated and RAS-wild-type lesions. Hepatology 27:1081-1088 (1998).
-
(1998)
Hepatology
, vol.27
, pp. 1081-1088
-
-
Kalkuhl, A.1
Troppmair, J.2
Buchmann, A.3
Stinchcombe, S.4
Buenemann, C.L.5
Rapp, U.R.6
Kaestner, K.7
Schwarz, M.8
-
46
-
-
0031428464
-
Dichloroacetic acid reduces Ha-ras codon 61 mutations in liver tumors from female B6C3F1 mice
-
Schroeder M, DeAngelo AB, Mass MJ. Dichloroacetic acid reduces Ha-ras codon 61 mutations in liver tumors from female B6C3F1 mice. Carcinogenesis 18:1675-1678 (1997).
-
(1997)
Carcinogenesis
, vol.18
, pp. 1675-1678
-
-
Schroeder, M.1
DeAngelo, A.B.2
Mass, M.J.3
-
47
-
-
0032531135
-
Effects of dichloroacetate-treatment on carbohydrate metabolism in B6C3F1 mice
-
Kato-Weinstein J, Lingohr MK, Thrall BD, Bull RJ. Effects of dichloroacetate-treatment on carbohydrate metabolism in B6C3F1 mice. Toxicology 130:141-154 (1998).
-
(1998)
Toxicology
, vol.130
, pp. 141-154
-
-
Kato-Weinstein, J.1
Lingohr, M.K.2
Thrall, B.D.3
Bull, R.J.4
-
48
-
-
0031723692
-
The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice
-
Merdink JL, Gonzalez-Leon A, Bull RJ, Schultz IR. The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice. Toxicol Sci 45:33-41 (1998).
-
(1998)
Toxicol Sci
, vol.45
, pp. 33-41
-
-
Merdink, J.L.1
Gonzalez-Leon, A.2
Bull, R.J.3
Schultz, I.R.4
-
49
-
-
0032940898
-
Dichloroacetate (DCA) dosimetry: Interpreting DCA-induced liver cancer dose response and the potential for DCA to contribute to trichloroethylene-induced liver cancer
-
Barton HA, Bull R, Schultz I, Andersen ME. Dichloroacetate (DCA) dosimetry: interpreting DCA-induced liver cancer dose response and the potential for DCA to contribute to trichloroethylene-induced liver cancer. Toxicol Lett 106:9-21 (1999).
-
(1999)
Toxicol Lett
, vol.106
, pp. 9-21
-
-
Barton, H.A.1
Bull, R.2
Schultz, I.3
Andersen, M.E.4
-
50
-
-
0022335175
-
Species differences in carcinogenicity and peroxisome proliferation due to trichloroethylene: A biochemical human hazard assessment
-
Elcombe CR. Species differences in carcinogenicity and peroxisome proliferation due to trichloroethylene: a biochemical human hazard assessment. Arch Toxicol (suppl 8):6-17 (1985).
-
(1985)
Arch Toxicol
, Issue.SUPPL. 8
, pp. 6-17
-
-
Elcombe, C.R.1
-
51
-
-
0029557218
-
Peroxisome proliferation: Current mechanisms relating to non-genotoxic carcinogenesis
-
Lake BG. Peroxisome proliferation: current mechanisms relating to non-genotoxic carcinogenesis. Toxicol Lett 82/83:673-681 (1995).
-
(1995)
Toxicol Lett
, vol.82-83
, pp. 673-681
-
-
Lake, B.G.1
-
52
-
-
0031838516
-
Do peroxisome proliferating compounds pose a carcinogenic hazard to humans
-
Cattley RC, DeLuca J, Elcombe C, Fenner-Crisp P, Lake BG, Marsman DS, Pastoor TA, Popp JA, Robinson DE, Schwetz B, et al. Do peroxisome proliferating compounds pose a carcinogenic hazard to humans. Regul Toxicol Pharmacol 27:47-60 (1997).
-
(1997)
Regul Toxicol Pharmacol
, vol.27
, pp. 47-60
-
-
Cattley, R.C.1
DeLuca, J.2
Elcombe, C.3
Fenner-Crisp, P.4
Lake, B.G.5
Marsman, D.S.6
Pastoor, T.A.7
Popp, J.A.8
Robinson, D.E.9
Schwetz, B.10
-
53
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
Issemann I, Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature (Lond) 347:645-650 (1990).
-
(1990)
Nature (Lond)
, vol.347
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
54
-
-
0026633654
-
Species differences in the metabolism of trichloroethylene to the carcinogenic metabolites trichloroacetate and dichloroacetate
-
Larson JL, Bull RJ. Species differences in the metabolism of trichloroethylene to the carcinogenic metabolites trichloroacetate and dichloroacetate. Toxicol Appl Pharmacol 115:273-285 (1992).
-
(1992)
Toxicol Appl Pharmacol
, vol.115
, pp. 273-285
-
-
Larson, J.L.1
Bull, R.J.2
-
55
-
-
0028997684
-
Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
Lee S-T, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Fernandez-Salguero PM, Westphal H, Gonzalez FJ. Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 15:3012-3022 (1995).
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3012-3022
-
-
Lee, S.-T.1
Pineau, T.2
Drago, J.3
Lee, E.J.4
Owens, J.W.5
Kroetz, D.L.6
Fernandez-Salguero, P.M.7
Westphal, H.8
Gonzalez, F.J.9
-
56
-
-
0031418657
-
Role of PPARα in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator, Wy-14,643
-
Peters JM, Cattley RC, Gonzalez FJ. Role of PPARα in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator, Wy-14,643. Carcinogenesis 18:2029-2033 (1997).
-
(1997)
Carcinogenesis
, vol.18
, pp. 2029-2033
-
-
Peters, J.M.1
Cattley, R.C.2
Gonzalez, F.J.3
-
57
-
-
0028966102
-
The human peroxisome proliferator-activated receptor (PPAR) subtype NUC1 represses the activation of hPPARα and thyroid hormone receptors
-
Jow L, Mukherjee R. The human peroxisome proliferator-activated receptor (PPAR) subtype NUC1 represses the activation of hPPARα and thyroid hormone receptors. J Biol Chem 270:3836-3840 (1995).
-
(1995)
J Biol Chem
, vol.270
, pp. 3836-3840
-
-
Jow, L.1
Mukherjee, R.2
-
58
-
-
0030047184
-
Identification of a peroxisome proliferator responsive element upstream of the human peroxisomal fatty acid acyl coenzyme A oxidase gene
-
Varanasi U, Chu RY, Huang Q, Castellon R, Yeldandi AV, Reddy JK. Identification of a peroxisome proliferator responsive element upstream of the human peroxisomal fatty acid acyl coenzyme A oxidase gene. J Biol Chem 271:2147-2155 (1996).
-
(1996)
J Biol Chem
, vol.271
, pp. 2147-2155
-
-
Varanasi, U.1
Chu, R.Y.2
Huang, Q.3
Castellon, R.4
Yeldandi, A.V.5
Reddy, J.K.6
-
59
-
-
0029294531
-
Peroxisome proliferator activated receptors: Transcriptional regulators of adipogenesis, lipid metabolism and more
-
Wahli W, Barissant O, Desvergne B. Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more. J Chem Biol 2:261-266 (1995).
-
(1995)
J Chem Biol
, vol.2
, pp. 261-266
-
-
Wahli, W.1
Barissant, O.2
Desvergne, B.3
-
60
-
-
0029144018
-
Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter
-
Schoonjans K, Watanabe M, Suzuki H, Mahfoudi A, Krey G, Wahli W, Grimaldi P, Staels B, Yamamoto T, Auwerx J. Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter. J Biol Chem 270:19269-19276 (1995).
-
(1995)
J Biol Chem
, vol.270
, pp. 19269-19276
-
-
Schoonjans, K.1
Watanabe, M.2
Suzuki, H.3
Mahfoudi, A.4
Krey, G.5
Wahli, W.6
Grimaldi, P.7
Staels, B.8
Yamamoto, T.9
Auwerx, J.10
-
61
-
-
0029084409
-
Peroxisome proliferator-activated receptor mediates cross-talk with thyroid hormone receptor by competition for the retinoid X receptor
-
Juge-Aubry CE, Gorla-Bajszczak A, Pernin A, Lemberger T, Wahli W, Burger AG, Meier CA. Peroxisome proliferator-activated receptor mediates cross-talk with thyroid hormone receptor by competition for the retinoid X receptor. J Biol Chem 270:18117-18122 (1995).
-
(1995)
J Biol Chem
, vol.270
, pp. 18117-18122
-
-
Juge-Aubry, C.E.1
Gorla-Bajszczak, A.2
Pernin, A.3
Lemberger, T.4
Wahli, W.5
Burger, A.G.6
Meier, C.A.7
-
62
-
-
0029067225
-
Signaling cross-talk between peroxisome-proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements
-
Keller H, Givel F, Perroud M, Wahli W. Signaling cross-talk between peroxisome-proliferator-activated receptor/retinoid X receptor and estrogen receptor through estrogen response elements. Mol Endocrinol 9:794-804 (1995).
-
(1995)
Mol Endocrinol
, vol.9
, pp. 794-804
-
-
Keller, H.1
Givel, F.2
Perroud, M.3
Wahli, W.4
-
63
-
-
26844521340
-
A 90-day chloroform inhalation study in female and male B6C3F1 mice: Implications for risk assessment
-
Larson JL, Templin MV, Wolf DG, Jamison KC, Leininger JR, Mery S, Morgan KT, Wong BA, Conolly RB, Butterworth BE. A 90-day chloroform inhalation study in female and male B6C3F1 mice: implications for risk assessment. Fundam Appl Toxicol 30:118-137 (1996).
-
(1996)
Fundam Appl Toxicol
, vol.30
, pp. 118-137
-
-
Larson, J.L.1
Templin, M.V.2
Wolf, D.G.3
Jamison, K.C.4
Leininger, J.R.5
Mery, S.6
Morgan, K.T.7
Wong, B.A.8
Conolly, R.B.9
Butterworth, B.E.10
-
64
-
-
0017840941
-
Influence of repeated liver regeneration or hepatic carcinogenesis by diethylnitrosamine in mice
-
Pound AW, McGuire LJ. Influence of repeated liver regeneration or hepatic carcinogenesis by diethylnitrosamine in mice. Br J Cancer 37:595-602 (1978).
-
(1978)
Br J Cancer
, vol.37
, pp. 595-602
-
-
Pound, A.W.1
McGuire, L.J.2
-
65
-
-
0026550568
-
Mitogen-indiced liver hyperplasia does not substitute for compensatory regeneration during promotion of chemical hepatocarcinogenesis
-
Ledda-Columbano GM, Coni P, Curto M, Giacomini L, Faa G, Sarma DSR, Columbano A. Mitogen-indiced liver hyperplasia does not substitute for compensatory regeneration during promotion of chemical hepatocarcinogenesis. Carcinogenesis 13:379-383 (1992).
-
(1992)
Carcinogenesis
, vol.13
, pp. 379-383
-
-
Ledda-Columbano, G.M.1
Coni, P.2
Curto, M.3
Giacomini, L.4
Faa, G.5
Sarma, D.S.R.6
Columbano, A.7
-
66
-
-
0021923010
-
Delineation of the role of metabolism in the hepatoxicity of trichloroethylene and perchloroethylene: A dose-effect study
-
Buben JA, O'Flaherty EJ. Delineation of the role of metabolism in the hepatoxicity of trichloroethylene and perchloroethylene: a dose-effect study. Toxicol Appl Pharmacol 78:105-122 (1985).
-
(1985)
Toxicol Appl Pharmacol
, vol.78
, pp. 105-122
-
-
Buben, J.A.1
O'Flaherty, E.J.2
-
67
-
-
0021808807
-
Biochemical, histological, and ultrastructural changes in rat and mouse liver following the administration of trichloroethylene: Possible relevance to species differences in hepatocarcinogenicity
-
Elcombe CR, Rose MS, Pratt IS. Biochemical, histological, and ultrastructural changes in rat and mouse liver following the administration of trichloroethylene: possible relevance to species differences in hepatocarcinogenicity. Toxicol Appl Pharmacol 79:365-376 (1985).
-
(1985)
Toxicol Appl Pharmacol
, vol.79
, pp. 365-376
-
-
Elcombe, C.R.1
Rose, M.S.2
Pratt, I.S.3
-
68
-
-
0027305268
-
The mitogenic potential of trichloroethylene in B6C3F1 mice
-
Dees C, Travis C. The mitogenic potential of trichloroethylene in B6C3F1 mice. Toxicol Lett 69:129-137 (1993).
-
(1993)
Toxicol Lett
, vol.69
, pp. 129-137
-
-
Dees, C.1
Travis, C.2
-
69
-
-
0020076523
-
Toxicology of trichloroethylene in the mouse
-
Tucker AN, Sanders VM, Barnes DW, Bradshaw TJ, White K Jr, Sain LE, Borzelleca JF, Munson AE. Toxicology of trichloroethylene in the mouse. Toxicol Appl Pharmacol 62:351-357 (1982).
-
(1982)
Toxicol Appl Pharmacol
, vol.62
, pp. 351-357
-
-
Tucker, A.N.1
Sanders, V.M.2
Barnes, D.W.3
Bradshaw, T.J.4
White K., Jr.5
Sain, L.E.6
Borzelleca, J.F.7
Munson, A.E.8
-
70
-
-
0033934377
-
Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites
-
Fisher JW. Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites. Environ Health Perspect 108(suppl 2):265-273 (2000).
-
(2000)
Environ Health Perspect
, vol.108
, Issue.SUPPL. 2
, pp. 265-273
-
-
Fisher, J.W.1
-
71
-
-
77957179532
-
Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde and dichloroacetic acid in male B6C3F1 mouse
-
Daniel FB, DeAngelo AB, Stober JA, Olson GR, Page NP. Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde and dichloroacetic acid in male B6C3F1 mouse. Fundam Appl Toxicol 19:159-168 (1992).
-
(1992)
Fundam Appl Toxicol
, vol.19
, pp. 159-168
-
-
Daniel, F.B.1
Deangelo, A.B.2
Stober, J.A.3
Olson, G.R.4
Page, N.P.5
-
72
-
-
0023510171
-
The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver
-
Herren-Freund SL, Pereira MA, Khoury MD, Olson G. The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver. Toxicol Appl Pharmacol 90:183-189 (1987).
-
(1987)
Toxicol Appl Pharmacol
, vol.90
, pp. 183-189
-
-
Herren-Freund, S.L.1
Pereira, M.A.2
Khoury, M.D.3
Olson, G.4
-
73
-
-
0025005335
-
Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate
-
Bull RJ, Sanchez IM, Nelson MA, Larson JL, Lansing AL. Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate. Toxicology 63:341-359 (1990).
-
(1990)
Toxicology
, vol.63
, pp. 341-359
-
-
Bull, R.J.1
Sanchez, I.M.2
Nelson, M.A.3
Larson, J.L.4
Lansing, A.L.5
-
74
-
-
26844538614
-
Carcinogenic activity of dichloroacetic acid and trichloroacetic acid in the liver of female B6C3F1 mice
-
Pereira MA. Carcinogenic activity of dichloroacetic acid and trichloroacetic acid in the liver of female B6C3F1 mice. Fundam Appl Toxicol 31:192-199 (1996).
-
(1996)
Fundam Appl Toxicol
, vol.31
, pp. 192-199
-
-
Pereira, M.A.1
-
76
-
-
0033601128
-
Hepatocarcinogenicity in the male B6C3F1 mouse following a lifetime exposure to dichloroacetic acid in the drinking water: Dose-response determination and modes of action
-
DeAngelo AB, George MH, House DE. Hepatocarcinogenicity in the male B6C3F1 mouse following a lifetime exposure to dichloroacetic acid in the drinking water: dose-response determination and modes of action. J Toxicol Environ Health 58:485-507 (1999).
-
(1999)
J Toxicol Environ Health
, vol.58
, pp. 485-507
-
-
Deangelo, A.B.1
George, M.H.2
House, D.E.3
-
77
-
-
0013814496
-
Metabolism of trichloroethylene in liver microsomes. II: Identification of the reaction product as chloral hydrate
-
Byington KH, Leibman KC. Metabolism of trichloroethylene in liver microsomes. II: Identification of the reaction product as chloral hydrate. Mol Pharmacol 1:247-254 (1965).
-
(1965)
Mol Pharmacol
, vol.1
, pp. 247-254
-
-
Byington, K.H.1
Leibman, K.C.2
-
78
-
-
0016661116
-
Isolation, characterization and quantitation of chloral hydrate as a transient metabolite of trichloroethylene in man using electron capture gas chromatography and mass fragmentography
-
Cole WJ, Mitchell RG, Salamonsen RF. Isolation, characterization and quantitation of chloral hydrate as a transient metabolite of trichloroethylene in man using electron capture gas chromatography and mass fragmentography. J Pharm Pharmacol 27:167-171 (1975).
-
(1975)
J Pharm Pharmacol
, vol.27
, pp. 167-171
-
-
Cole, W.J.1
Mitchell, R.G.2
Salamonsen, R.F.3
-
79
-
-
0016661116
-
Isolation, characterization and quantitation of chloral hydrate as a transient metabolite of trichloroethylene in man using electron capture gas chromatography and mass fragmentography
-
Cole WJ, Mitchell RG, Salamonsen RF. Isolation, characterization and quantitation of chloral hydrate as a transient metabolite of trichloroethylene in man using electron capture gas chromatography and mass fragmentography. J Pharm Pharmacol 27:167-171 (1975).
-
(1975)
J Pharm Pharmacol
, vol.27
, pp. 167-171
-
-
Cole, W.J.1
Mitchell, R.G.2
Salamonsen, R.F.3
-
80
-
-
0023180184
-
The metabolic ratio as a function of chloral hydrate dose and intracellular redox as a function of chloral hydrate dose and intracellular redox state in the perfused rat liver
-
Kawamoto T, Hobara T, Kobayashi H, Iwamoto S, Sakai T, Takano T, Miyazaki Y. The metabolic ratio as a function of chloral hydrate dose and intracellular redox as a function of chloral hydrate dose and intracellular redox state in the perfused rat liver. Pharmacol Toxicol 60:325-329 (1987).
-
(1987)
Pharmacol Toxicol
, vol.60
, pp. 325-329
-
-
Kawamoto, T.1
Hobara, T.2
Kobayashi, H.3
Iwamoto, S.4
Sakai, T.5
Takano, T.6
Miyazaki, Y.7
-
81
-
-
0027385555
-
Relative formation of dichloroacetate and trichloroacetate from trichloroethylene in male B6C3F1 mice
-
Templin MV, Parker JC, Bull RJ. Relative formation of dichloroacetate and trichloroacetate from trichloroethylene in male B6C3F1 mice. Toxicol Appl Pharmacol 123: 1-8 (1993).
-
(1993)
Toxicol Appl Pharmacol
, vol.123
, pp. 1-8
-
-
Templin, M.V.1
Parker, J.C.2
Bull, R.J.3
-
82
-
-
0028963115
-
Factors affecting species differences in the kinetics of metabolites of trichloroethylene
-
Templin MV, Stevens DK, Stenner RD, Bonate PL, Tuman D, Bull RJ. Factors affecting species differences in the kinetics of metabolites of trichloroethylene. J Toxicol Environ Health 44:435-447 (1995).
-
(1995)
J Toxicol Environ Health
, vol.44
, pp. 435-447
-
-
Templin, M.V.1
Stevens, D.K.2
Stenner, R.D.3
Bonate, P.L.4
Tuman, D.5
Bull, R.J.6
-
83
-
-
0031009079
-
Enterohepatic recirculation of trichloroethanol glucuronide as a significant source of trichloroacetic acid in the metabolism of trichloroethylene
-
Stenner FD, Merdink JL, Templin MV, Stevens DK, Springer DL, Bull RJ. Enterohepatic recirculation of trichloroethanol glucuronide as a significant source of trichloroacetic acid in the metabolism of trichloroethylene. Drug Metab Dispos 25:529-535 (1997).
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 529-535
-
-
Stenner, F.D.1
Merdink, J.L.2
Templin, M.V.3
Stevens, D.K.4
Springer, D.L.5
Bull, R.J.6
-
84
-
-
0025734238
-
Mutagenicity and cytotoxicity of two regioisomeric mercapturic acids and cysteine conjugates of trichlorothylene
-
Commandeur JNM, Boogaard PJ, Mulder GJ, Vermeulen NPE. Mutagenicity and cytotoxicity of two regioisomeric mercapturic acids and cysteine conjugates of trichlorothylene. Arch Toxicol 65:373-380 (1991).
-
(1991)
Arch Toxicol
, vol.65
, pp. 373-380
-
-
Commandeur, J.N.M.1
Boogaard, P.J.2
Mulder, G.J.3
Vermeulen, N.P.E.4
-
85
-
-
0022503191
-
Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: Possible explanation for its nephrocarcinogenicity in male rats
-
Dekant W, Metzler M, Henschler D. Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: possible explanation for its nephrocarcinogenicity in male rats. Biochem Pharmacol 35:2455-2458 (1986).
-
(1986)
Biochem Pharmacol
, vol.35
, pp. 2455-2458
-
-
Dekant, W.1
Metzler, M.2
Henschler, D.3
-
86
-
-
0027267051
-
Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysleine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: Implications for the risk of trichloroethene exposure
-
Bimer G, Vamvakas S, Dekant W, Henschler D. Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysleine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: implications for the risk of trichloroethene exposure. Environ Health Perspect 99:281-284 (1993).
-
(1993)
Environ Health Perspect
, vol.99
, pp. 281-284
-
-
Bimer, G.1
Vamvakas, S.2
Dekant, W.3
Henschler, D.4
-
87
-
-
0028929211
-
Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene
-
Henschler D, Vamvakas S, Lammert M, DeKant W, Krause B, Thomas B, Ulm K. Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene. Arch Toxicol 69:291-299 (1995).
-
(1995)
Arch Toxicol
, vol.69
, pp. 291-299
-
-
Henschler, D.1
Vamvakas, S.2
Lammert, M.3
DeKant, W.4
Krause, B.5
Thomas, B.6
Ulm, K.7
-
88
-
-
0030768274
-
A critical review of epidemiology studies of trichloroethylene and perchloroethylene and risk of renal-cell cancer
-
McLaughlin JK, Blot WJ. A critical review of epidemiology studies of trichloroethylene and perchloroethylene and risk of renal-cell cancer. Int Arch Occup Environ Health 70:222-231 (1997).
-
(1997)
Int Arch Occup Environ Health
, vol.70
, pp. 222-231
-
-
McLaughlin, J.K.1
Blot, W.J.2
-
89
-
-
18544403466
-
Renal cell cancer correlated with occupational exposure to trichloroethene
-
Vamvakas S, Bruning T, Thomassen B, Lammert M, Baumiller A, Bolt HM, Dekant W, Henschler D, Ulm K. Renal cell cancer correlated with occupational exposure to trichloroethene. J Cancer Res Clin Oncol 124:374-382 (1998).
-
(1998)
J Cancer Res Clin Oncol
, vol.124
, pp. 374-382
-
-
Vamvakas, S.1
Bruning, T.2
Thomassen, B.3
Lammert, M.4
Baumiller, A.5
Bolt, H.M.6
Dekant, W.7
Henschler, D.8
Ulm, K.9
-
90
-
-
0029026852
-
Immunohistochemical analysis of dichloroacetic acid (DCA)-induced hepatocarcinogenesis in male Fischer (F344) rats
-
Richmond RE, Carter JH, Carter HW, Daniel FB, DeAngelo AB. Immunohistochemical analysis of dichloroacetic acid (DCA)-induced hepatocarcinogenesis in male Fischer (F344) rats. Cancer Lett 92:67-76 (1995).
-
(1995)
Cancer Lett
, vol.92
, pp. 67-76
-
-
Richmond, R.E.1
Carter, J.H.2
Carter, H.W.3
Daniel, F.B.4
DeAngelo, A.B.5
-
91
-
-
0030592952
-
The carcinogenicity of dichloroacetic acid in the male Fischer 344 rat
-
DeAngelo AB, Daniel FB, Most BM, Olson GR. The carcinogenicity of dichloroacetic acid in the male Fischer 344 rat. Toxicology 114:207-221 (1996).
-
(1996)
Toxicology
, vol.114
, pp. 207-221
-
-
DeAngelo, A.B.1
Daniel, F.B.2
Most, B.M.3
Olson, G.R.4
-
92
-
-
0027726817
-
Advances in research on carcinogenic and genotoxic by-products of chlorine disinfection: Chlorinated hydroxyfuranones and chlorinated acetic acids
-
Daniel FB, Meier JR, DeAngelo AB. Advances in research on carcinogenic and genotoxic by-products of chlorine disinfection: chlorinated hydroxyfuranones and chlorinated acetic acids. Ann Ist Super Sanita 29:279-291 (1993).
-
(1993)
Ann Ist Super Sanita
, vol.29
, pp. 279-291
-
-
Daniel, F.B.1
Meier, J.R.2
Deangelo, A.B.3
-
93
-
-
0030694391
-
Failure of monochloroacetic acid and trichloroactic acid administered in the drinking water to produce liver cancer in male F344/N rats
-
DeAngelo AB, Daniel FB, Most BM, Olson GR. Failure of monochloroacetic acid and trichloroactic acid administered in the drinking water to produce liver cancer in male F344/N rats. J Toxicol Environ Health 52:425-445 (1997).
-
(1997)
J Toxicol Environ Health
, vol.52
, pp. 425-445
-
-
DeAngelo, A.B.1
Daniel, F.B.2
Most, B.M.3
Olson, G.R.4
-
95
-
-
0018170790
-
A study of the mutagenicity of anesthetics and their metabolites
-
Waskell L. A study of the mutagenicity of anesthetics and their metabolites. Mutat Res 57:141-143 (1978).
-
(1978)
Mutat Res
, vol.57
, pp. 141-143
-
-
Waskell, L.1
-
96
-
-
0018905425
-
Mutagenicity of halogenated aliphatic hydrocarbons in Salmonella typhimurium, Streptomyces coelicolor and Aspergillis nidulans
-
Bignami M, Conti G, Conti L, Crebelli R, Misuraca F, Puglia AM, Randazzo R, Sciandrello G, Carere A. Mutagenicity of halogenated aliphatic hydrocarbons in Salmonella typhimurium, Streptomyces coelicolor and Aspergillis nidulans. Chem-Biol Interact 30:9-23 (1980).
-
(1980)
Chem-Biol Interact
, vol.30
, pp. 9-23
-
-
Bignami, M.1
Conti, G.2
Conti, L.3
Crebelli, R.4
Misuraca, F.5
Puglia, A.M.6
Randazzo, R.7
Sciandrello, G.8
Carere, A.9
-
97
-
-
0025996671
-
Evaluation of the mutagenicity of chloral hydrate in vitro and in vivo
-
Leuschner J, Leuschner F. Evaluation of the mutagenicity of chloral hydrate in vitro and in vivo. Drug Res 41:1101-1103 (1991).
-
(1991)
Drug Res
, vol.41
, pp. 1101-1103
-
-
Leuschner, J.1
Leuschner, F.2
-
98
-
-
0023801272
-
Mechanistic studies on chloral toxicity: Relationship to trichloroethylene carcinogenesis
-
Keller DA, Heck HA. Mechanistic studies on chloral toxicity: relationship to trichloroethylene carcinogenesis. Toxicol Lett 42:183-191 (1988).
-
(1988)
Toxicol Lett
, vol.42
, pp. 183-191
-
-
Keller, D.A.1
Heck, H.A.2
-
99
-
-
0021184264
-
Genetic and biochemical investigation on chloral hydrate in vitro and in vivo
-
Bronzetti G, Galli A, Corsi C, Cundari E, Del Carratore R, Nieri R, Paolini M. Genetic and biochemical investigation on chloral hydrate in vitro and in vivo. Mutat Res 141:19-22 (1984).
-
(1984)
Mutat Res
, vol.141
, pp. 19-22
-
-
Bronzetti, G.1
Galli, A.2
Corsi, C.3
Cundari, E.4
Del Carratore, R.5
Nieri, R.6
Paolini, M.7
-
100
-
-
0023116885
-
Chloral hydrate, methylmercury hydroxide and ethidium bromide affect chromosomal segregation during meosis of Saccharomyces cerevisiae
-
Sora S, Carbone MJA. Chloral hydrate, methylmercury hydroxide and ethidium bromide affect chromosomal segregation during meosis of Saccharomyces cerevisiae. Mutat Res 190:13-17 (1987).
-
(1987)
Mutat Res
, vol.190
, pp. 13-17
-
-
Sora, S.1
Carbone, M.J.A.2
-
101
-
-
0025006007
-
The induction of aneuploidy in cultured Chinese hamster cells by propionaldehyde and chloral hydrate
-
Furnus CC, Ulrich MA, Terreros MC, Dulout FN. The induction of aneuploidy in cultured Chinese hamster cells by propionaldehyde and chloral hydrate. Mutagenesis 5:323-326 (1990).
-
(1990)
Mutagenesis
, vol.5
, pp. 323-326
-
-
Furnus, C.C.1
Ulrich, M.A.2
Terreros, M.C.3
Dulout, F.N.4
-
102
-
-
0025132303
-
Aneuploidy induced by chloral hydrate detected in human lymphocytes with Y97 probe
-
Vagnarelli P, De Sario A, De Carli L. Aneuploidy induced by chloral hydrate detected in human lymphocytes with Y97 probe. Mutagenesis 5:591-592 (1990).
-
(1990)
Mutagenesis
, vol.5
, pp. 591-592
-
-
Vagnarelli, P.1
De Sario, A.2
De Carli, L.3
-
103
-
-
0021717844
-
Nondisjunction induced in mouse spermatogenesis by chloral hydrate, a metabolite of trichloroethylene
-
Russo A, Pacchierotti F, Metalli P. Nondisjunction induced in mouse spermatogenesis by chloral hydrate, a metabolite of trichloroethylene. Environ Mutagen 6:695-703 (1984).
-
(1984)
Environ Mutagen
, vol.6
, pp. 695-703
-
-
Russo, A.1
Pacchierotti, F.2
Metalli, P.3
-
104
-
-
0026662739
-
Ninety-day toxicity study of chloral hydrate in the Sprague-Dawley rat
-
Daniel FB, Robinson M, Stober JA, Page NP, Olsor GR. Ninety-day toxicity study of chloral hydrate in the Sprague-Dawley rat. Drug Chem Toxicol 15:217-232 (1992).
-
(1992)
Drug Chem Toxicol
, vol.15
, pp. 217-232
-
-
Daniel, F.B.1
Robinson, M.2
Stober, J.A.3
Page, N.P.4
Olsor, G.R.5
-
106
-
-
0020332554
-
Toxicology of chloral hydrate in the mouse
-
Sanders VM, Kauffmann BM, White KL Jr, Douglas KA, Barnes DW, Sain LE, Bradshaw TJ, Borzelleca JF, Munson AE. Toxicology of chloral hydrate in the mouse. Environ Health Perspect 44:137-146 (1982).
-
(1982)
Environ Health Perspect
, vol.44
, pp. 137-146
-
-
Sanders, V.M.1
Kauffmann, B.M.2
White K.L., Jr.3
Douglas, K.A.4
Barnes, D.W.5
Sain, L.E.6
Bradshaw, T.J.7
Borzelleca, J.F.8
Munson, A.E.9
-
107
-
-
0024462258
-
Dichloroacetic acid and trichloroacetic acid-induced DNA strand breaks are independent of peroxisome proliferation
-
Nelson MA, Lansing AJ, Sanchez IM, Bull RJ, Springer DL. Dichloroacetic acid and trichloroacetic acid-induced DNA strand breaks are independent of peroxisome proliferation. Toxicology 58:239-248 (1989).
-
(1989)
Toxicology
, vol.58
, pp. 239-248
-
-
Nelson, M.A.1
Lansing, A.J.2
Sanchez, I.M.3
Bull, R.J.4
Springer, D.L.5
-
108
-
-
0025882831
-
Trichloroacetic acid: Studies on uptake and effects on hepatic DNA and liver growth in mice
-
Styles JA, Wyatt I, Coutts C. Trichloroacetic acid: studies on uptake and effects on hepatic DNA and liver growth in mice. Carcinogenesis 12:1715-1719 (1991).
-
(1991)
Carcinogenesis
, vol.12
, pp. 1715-1719
-
-
Styles, J.A.1
Wyatt, I.2
Coutts, C.3
-
109
-
-
0026486784
-
Analysis of DNA strand breaks induced in rodent liver in vivo, hepatocytes in primary culture, and a human cell line by chlorinated acetic acids and chlorinated acetaldehydes
-
Chang LW, Daniel FB, DeAngelo AB. Analysis of DNA strand breaks induced in rodent liver in vivo, hepatocytes in primary culture, and a human cell line by chlorinated acetic acids and chlorinated acetaldehydes. Environ Mol Mutagen 20:277-298 (1992).
-
(1992)
Environ Mol Mutagen
, vol.20
, pp. 277-298
-
-
Chang, L.W.1
Daniel, F.B.2
Deangelo, A.B.3
-
110
-
-
26844575256
-
Lipid peroxidation and formation of 8-hydroxydeoxyguanosine from acute doses of halogenated acetic acids
-
Austin EW, Parish JM, Kinder D.H, Bull RJ. Lipid peroxidation and formation of 8-hydroxydeoxyguanosine from acute doses of halogenated acetic acids. Fundam Appl Toxicol 31:77-82 (1996).
-
(1996)
Fundam Appl Toxicol
, vol.31
, pp. 77-82
-
-
Austin, E.W.1
Parish, J.M.2
Kinder, D.H.3
Bull, R.J.4
-
111
-
-
0029890311
-
Haloacetate-induced oxidative damage to DNA in the liver of male B6C3F1 mice
-
Parrish JM, Austin EW, Stevens DK, Kinder DH, Bull RJ. Haloacetate-induced oxidative damage to DNA in the liver of male B6C3F1 mice. Toxicology 110:103-111 (1996).
-
(1996)
Toxicology
, vol.110
, pp. 103-111
-
-
Parrish, J.M.1
Austin, E.W.2
Stevens, D.K.3
Kinder, D.H.4
Bull, R.J.5
-
112
-
-
0027489205
-
Repair of 8-hydroxyguanine in DNA by mammalian N-methylpurine-DNA glycosylase
-
Bessho T, Roy R, Yamamoto K, Nishimura S, Tano K, Mitra, S. Repair of 8-hydroxyguanine in DNA by mammalian N-methylpurine-DNA glycosylase. Proc Natl Acad Sci USA 90:8901-8904 (1993).
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8901-8904
-
-
Bessho, T.1
Roy, R.2
Yamamoto, K.3
Nishimura, S.4
Tano, K.5
Mitra, S.6
-
113
-
-
0029872439
-
Promotion by dichloroacetic acid and trichloroacetic acid of N-methyl-N-nitrosourea-initiated cancer in the liver of female B6C3F1 mice
-
Pereira MA, Phelps JB. Promotion by dichloroacetic acid and trichloroacetic acid of N-methyl-N-nitrosourea-initiated cancer in the liver of female B6C3F1 mice. Cancer Lett 102:133-141 (1996).
-
(1996)
Cancer Lett
, vol.102
, pp. 133-141
-
-
Pereira, M.A.1
Phelps, J.B.2
-
114
-
-
0030606222
-
Loss of heterozygosity on chromosome 6 in dichloroacetic and trichloroacetic acid-induced liver tumors in female B6C3F1 mice
-
Tao L, Li K, Kramer PM, Pereira MA. Loss of heterozygosity on chromosome 6 in dichloroacetic and trichloroacetic acid-induced liver tumors in female B6C3F1 mice. Cancer Lett 108:257-261 (1996).
-
(1996)
Cancer Lett
, vol.108
, pp. 257-261
-
-
Tao, L.1
Li, K.2
Kramer, P.M.3
Pereira, M.A.4
-
116
-
-
0024389625
-
Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acids
-
DeAngelo AB, Daniel FB, McMillan L, Wernsing P, Savage RE Jr. Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acids. Toxicol Appl Pharmacol 101:285-298 (1989).
-
(1989)
Toxicol Appl Pharmacol
, vol.101
, pp. 285-298
-
-
Deangelo, A.B.1
Daniel, F.B.2
McMillan, L.3
Wernsing, P.4
Savage R.E., Jr.5
-
117
-
-
0031172480
-
Differences in phenotype and cell replicative behavior of hepatic tumors inducted by dichloroacetate (DCA) and trichloroacetate (TCA)
-
Stauber AJ, Bull RJ. Differences in phenotype and cell replicative behavior of hepatic tumors inducted by dichloroacetate (DCA) and trichloroacetate (TCA). Toxicol Appl Pharmacol 144:235-246 (1997).
-
(1997)
Toxicol Appl Pharmacol
, vol.144
, pp. 235-246
-
-
Stauber, A.J.1
Bull, R.J.2
-
118
-
-
0025828052
-
Liver tumor promotion: Effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-β1 expression
-
Jirtle RL, Meyer SA. Liver tumor promotion: effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-β1 expression. Dig Dis Sci 36:659-668 (1991).
-
(1991)
Dig Dis Sci
, vol.36
, pp. 659-668
-
-
Jirtle, R.L.1
Meyer, S.A.2
-
119
-
-
0032103380
-
Dichloroacetate and trichloroacetate promote clonal expansion of anchorage-independent hepatocytes in vivo and in vitro
-
Stauber AJ, Bull RJ, Thrall BD. Dichloroacetate and trichloroacetate promote clonal expansion of anchorage-independent hepatocytes in vivo and in vitro. Toxicol Appl Pharmacol 150:287-294 (1998).
-
(1998)
Toxicol Appl Pharmacol
, vol.150
, pp. 287-294
-
-
Stauber, A.J.1
Bull, R.J.2
Thrall, B.D.3
-
120
-
-
0025004561
-
Early induction of reparative hyperplasia in the liver of B6C3F1 mice treated with dichloroacetate and trichloroacetate
-
Sanchez IM, Bull RJ. Early induction of reparative hyperplasia in the liver of B6C3F1 mice treated with dichloroacetate and trichloroacetate. Toxicology 64:33-46 (1990).
-
(1990)
Toxicology
, vol.64
, pp. 33-46
-
-
Sanchez, I.M.1
Bull, R.J.2
-
121
-
-
0343558301
-
Effect of dichloroacetic acid and trichloroacetic acid upon cell proliferation in B6C3F1 mice
-
Denver, CO
-
Pereira MA. Effect of dichloroacetic acid and trichloroacetic acid upon cell proliferation in B6C3F1 mice. Final Project Report to the AWWA Research Foundation, Denver, CO 1995.
-
(1995)
Final Project Report to the AWWA Research Foundation
-
-
Pereira, M.A.1
-
122
-
-
0019432246
-
Dichloroacetate, sodium: 3-month oral toxicity studies in rats and dogs
-
Katz R, Tai CN, Deiner RM, McConnel RF, Semonick DE. Dichloroacetate, sodium: 3-month oral toxicity studies in rats and dogs. Toxicol Appl Pharmacol 57:273-287 (1981).
-
(1981)
Toxicol Appl Pharmacol
, vol.57
, pp. 273-287
-
-
Katz, R.1
Tai, C.N.2
Deiner, R.M.3
McConnel, R.F.4
Semonick, D.E.5
-
123
-
-
0019994207
-
Comparison of the metabolic and toxic effects of 2-chloroproprionate and dichloroacetate
-
Yount EA, Felten SY, O'Connor BL, Peterson RG, Powell RS, Yum MN, Harris RA. Comparison of the metabolic and toxic effects of 2-chloroproprionate and dichloroacetate. J Pharmacol Exp Ther 222:501-508 (1982).
-
(1982)
J Pharmacol Exp Ther
, vol.222
, pp. 501-508
-
-
Yount, E.A.1
Felten, S.Y.2
O'Connor, B.L.3
Peterson, R.G.4
Powell, R.S.5
Yum, M.N.6
Harris, R.A.7
-
125
-
-
0028169616
-
Dichloroacetic acid and related compounds: Induction of prophage in E. coli and mutagenicity and mutation spectra in Salmonella TA100
-
DeMarini DM, Perry E, Shelton ML. Dichloroacetic acid and related compounds: induction of prophage in E. coli and mutagenicity and mutation spectra in Salmonella TA100. Mutagenesis 9:429-437 (1994).
-
(1994)
Mutagenesis
, vol.9
, pp. 429-437
-
-
Demarini, D.M.1
Perry, E.2
Shelton, M.L.3
-
126
-
-
0006374335
-
The acute oral toxicity of acetic, chloroacetic, dichloroacetic and trichloroacetic acids
-
Woodard G, Lange SW, Nelson KW, Calvery HO. The acute oral toxicity of acetic, chloroacetic, dichloroacetic and trichloroacetic acids. J Ind Hyg Toxicol 23:78-82 (1941).
-
(1941)
J Ind Hyg Toxicol
, vol.23
, pp. 78-82
-
-
Woodard, G.1
Lange, S.W.2
Nelson, K.W.3
Calvery, H.O.4
-
127
-
-
0023010822
-
Genotoxic effects in cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations
-
Brusick D. Genotoxic effects in cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations. Environ Mutagen 8:879-886 (1986).
-
(1986)
Environ Mutagen
, vol.8
, pp. 879-886
-
-
Brusick, D.1
-
128
-
-
0030869962
-
Comparative genotoxicity of halogenated acetic acids found in drinking water
-
Giller S, Le Curieux F, Erb F, Marzin D. Comparative genotoxicity of halogenated acetic acids found in drinking water. Mutagenesis 12:321-328 (1997).
-
(1997)
Mutagenesis
, vol.12
, pp. 321-328
-
-
Giller, S.1
Le Curieux, F.2
Erb, F.3
Marzin, D.4
-
129
-
-
26944489113
-
Absence of mutagenic effects of sodium dichloroacetate
-
Fox AW, Yang X, Murli H, Lawlor TE, Cifone MA, Reno FE. Absence of mutagenic effects of sodium dichloroacetate. Fundam Appl Toxicol 32:87-95 (1996).
-
(1996)
Fundam Appl Toxicol
, vol.32
, pp. 87-95
-
-
Fox, A.W.1
Yang, X.2
Murli, H.3
Lawlor, T.E.4
Cifone, M.A.5
Reno, F.E.6
-
130
-
-
9044240470
-
In vivo genotoxicity of dichloroacetic acid: Evaluation with the mouse peripheral blood micronucleus assay and the single cell gel assay
-
Fuscoe JC, Afshari AJ, George MH, DeAngelo AB, Tice RR, Salman R, Allen JW. In vivo genotoxicity of dichloroacetic acid: Evaluation with the mouse peripheral blood micronucleus assay and the single cell gel assay. Environ Mol Mutagen 27:1-9 (1996).
-
(1996)
Environ Mol Mutagen
, vol.27
, pp. 1-9
-
-
Fuscoe, J.C.1
Afshari, A.J.2
George, M.H.3
Deangelo, A.B.4
Tice, R.R.5
Salman, R.6
Allen, J.W.7
-
131
-
-
0031418204
-
Assessment of the mutagenicity of dichloroacetic acid in lacl transgenic B6C3F1 mouse liver
-
Leavitt SA, DeAngelo AB, George MH, Ross JA. Assessment of the mutagenicity of dichloroacetic acid in lacl transgenic B6C3F1 mouse liver. Carcinogenesis 18:2101-2106 (1997).
-
(1997)
Carcinogenesis
, vol.18
, pp. 2101-2106
-
-
Leavitt, S.A.1
DeAngelo, A.B.2
George, M.H.3
Ross, J.A.4
-
133
-
-
0018787079
-
Mechanism of pyruvate inhibition of kidney pyruvate dehydrogenase kinase and synergistic inhibition by pyruvate and ADP
-
Pratt ML, Roche TE. Mechanism of pyruvate inhibition of kidney pyruvate dehydrogenase kinase and synergistic inhibition by pyruvate and ADP. J Biol Chem 254:7191-7196 (1979).
-
(1979)
J Biol Chem
, vol.254
, pp. 7191-7196
-
-
Pratt, M.L.1
Roche, T.E.2
-
134
-
-
0006350581
-
Dichloroacetate (DCA) modulates insulin signaling
-
Smith MK, Thrall BD, Bull RJ. Dichloroacetate (DCA) modulates insulin signaling. Toxicologist 36:1133 (1997).
-
(1997)
Toxicologist
, vol.36
, pp. 1133
-
-
Smith, M.K.1
Thrall, B.D.2
Bull, R.J.3
-
135
-
-
0030008955
-
Insulin receptor substrate 1 overexpression in human hepatocellular carcinoma prevents transforming growth factor β1-induced apoptosis
-
Tanaka S, Wands JR. Insulin receptor substrate 1 overexpression in human hepatocellular carcinoma prevents transforming growth factor β1-induced apoptosis. Cancer Res 56:3391-3394 (1996).
-
(1996)
Cancer Res
, vol.56
, pp. 3391-3394
-
-
Tanaka, S.1
Wands, J.R.2
-
136
-
-
0029620853
-
Biochemical, pathologic and morphometric alterations induced in male B6C3F1 mouse liver by short-term exposure to dichloroacetic acid
-
Carter JH, Carter HW, DeAngelo AB. Biochemical, pathologic and morphometric alterations induced in male B6C3F1 mouse liver by short-term exposure to dichloroacetic acid. Toxicol Lett 81:55-71 (1995).
-
(1995)
Toxicol Lett
, vol.81
, pp. 55-71
-
-
Carter, J.H.1
Carter, H.W.2
Deangelo, A.B.3
-
137
-
-
0029150242
-
In vivo administration of dichloroacetic acid suppresses spontaneous apoptosis in murine hepatocytes
-
Snyder RD, Pullman J, Carter JH, Carter HW, DeAngelo AB. In vivo administration of dichloroacetic acid suppresses spontaneous apoptosis in murine hepatocytes. Cancer Res 55:3702-3705 (1995).
-
(1995)
Cancer Res
, vol.55
, pp. 3702-3705
-
-
Snyder, R.D.1
Pullman, J.2
Carter, J.H.3
Carter, H.W.4
DeAngelo, A.B.5
-
138
-
-
0034646944
-
In vivo MRI measurements of tumor growth induced by dichloroacetate implications for mode of action
-
Miller JH, Minard KR, Wind RA, Orner GA, Sasser LB, Bull RJ. In vivo MRI measurements of tumor growth induced by dichloroacetate implications for mode of action. Toxicology 145:115-125 (2000).
-
(2000)
Toxicology
, vol.145
, pp. 115-125
-
-
Miller, J.H.1
Minard, K.R.2
Wind, R.A.3
Orner, G.A.4
Sasser, L.B.5
Bull, R.J.6
-
140
-
-
0025160366
-
Subchronic 90 day toxicity of dichloroacetic and trichloroacetic acid in rats
-
Mather GG, Exon JH, Koller LD. Subchronic 90 day toxicity of dichloroacetic and trichloroacetic acid in rats. Toxicology 64:71-80 (1990).
-
(1990)
Toxicology
, vol.64
, pp. 71-80
-
-
Mather, G.G.1
Exon, J.H.2
Koller, L.D.3
-
142
-
-
0030726886
-
Pharmacokinetics and metabolism of dichloroacetate in the F344 rat after prior administration in drinking water
-
Gonzalez-Leon A, Schultz IR, Xu G, Bull RJ. Pharmacokinetics and metabolism of dichloroacetate in the F344 rat after prior administration in drinking water. Toxicol Appl Pharmacol 146:189-195 (1997).
-
(1997)
Toxicol Appl Pharmacol
, vol.146
, pp. 189-195
-
-
Gonzalez-Leon, A.1
Schultz, I.R.2
Xu, G.3
Bull, R.J.4
-
143
-
-
0030880918
-
Dissimilar characteristics of N-methyl-N-nitrosourea-initiated foci and tumors promoted by dichloroacetic acid or trichloroacetic acid in the liver of female B6C3F1 mice
-
Latendressse JR, Pereira MA. Dissimilar characteristics of N-methyl-N-nitrosourea-initiated foci and tumors promoted by dichloroacetic acid or trichloroacetic acid in the liver of female B6C3F1 mice. Toxicol Pathol 25:433-440 (1997).
-
(1997)
Toxicol Pathol
, vol.25
, pp. 433-440
-
-
Latendressse, J.R.1
Pereira, M.A.2
-
144
-
-
0031879943
-
Effect of dichloroacetic acid and trichloroacetic acid on DNA methylation in liver tumors of female B6C3F1 mice
-
Tao L, Kramer PM, Ge R, Pereira MA. Effect of dichloroacetic acid and trichloroacetic acid on DNA methylation in liver tumors of female B6C3F1 mice. Toxicol Sci 43:139-144 (1998).
-
(1998)
Toxicol Sci
, vol.43
, pp. 139-144
-
-
Tao, L.1
Kramer, P.M.2
Ge, R.3
Pereira, M.A.4
-
145
-
-
0032972477
-
Physiologically-based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice
-
Greenberg MS, Burton GA, Fisher JW. Physiologically-based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice. Toxicol Appl Pharmacol 154:264-278 (1999).
-
(1999)
Toxicol Appl Pharmacol
, vol.154
, pp. 264-278
-
-
Greenberg, M.S.1
Burton, G.A.2
Fisher, J.W.3
-
146
-
-
0030453962
-
Pharmacokinetic analysis of chloral hydrate and its metabolism in B6C3F1 mice
-
Abbas RR, Seckel CS, Kidney JK, Fisher JW. Pharmacokinetic analysis of chloral hydrate and its metabolism in B6C3F1 mice. Drug Metab Dispos 24:1340-1346 (1996).
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 1340-1346
-
-
Abbas, R.R.1
Seckel, C.S.2
Kidney, J.K.3
Fisher, J.W.4
-
147
-
-
0032585881
-
trans-Activation of PPARα and PPARγ by structurally diverse environmental chemicals
-
Maloney EK, Waxman DJ. trans-Activation of PPARα and PPARγ by structurally diverse environmental chemicals. Toxicol Appl Pharmacol 161:209-218 (1999).
-
(1999)
Toxicol Appl Pharmacol
, vol.161
, pp. 209-218
-
-
Maloney, E.K.1
Waxman, D.J.2
-
148
-
-
0021842689
-
Species differences in response to trichloroethylene. I: Pharmacokinetics in mice and rats
-
Prout MS, Provan WM, Green T. Species differences in response to trichloroethylene. I: Pharmacokinetics in mice and rats. Toxicol Appl Pharmacol 79:389-400 (1985).
-
(1985)
Toxicol Appl Pharmacol
, vol.79
, pp. 389-400
-
-
Prout, M.S.1
Provan, W.M.2
Green, T.3
-
149
-
-
0018851265
-
Consideration of the evidence for mechanisms of 1,1,2-trichloroethylene metabolism, including new identification of its dichloroacetic acid and trichloroacetic acid metabolites in mice
-
Hathway DE. Consideration of the evidence for mechanisms of 1,1,2-trichloroethylene metabolism, including new identification of its dichloroacetic acid and trichloroacetic acid metabolites in mice. Cancer Lett 8:263-269 (1980).
-
(1980)
Cancer Lett
, vol.8
, pp. 263-269
-
-
Hathway, D.E.1
-
150
-
-
0027253691
-
The role of dichloroacetate in the hepatocarcinogenicity of trichloroethylene
-
Bull RJ, Templin M, Larson JL, Stevens DK. The role of dichloroacetate in the hepatocarcinogenicity of trichloroethylene. Toxicol Lett 68:203-211 (1993).
-
(1993)
Toxicol Lett
, vol.68
, pp. 203-211
-
-
Bull, R.J.1
Templin, M.2
Larson, J.L.3
Stevens, D.K.4
-
151
-
-
0030077331
-
Regulation of signal transduction during liver regeneration
-
Diehl AM, Rai RM. Regulation of signal transduction during liver regeneration. FASEB J 10:216-227 (1996).
-
(1996)
FASEB J
, vol.10
, pp. 216-227
-
-
Diehl, A.M.1
Rai, R.M.2
-
152
-
-
0029012444
-
Apoptosis and hepatobiliary disease
-
Patel T, Gores GJ. Apoptosis and hepatobiliary disease. Hepatology 21:1725-1741 (1995).
-
(1995)
Hepatology
, vol.21
, pp. 1725-1741
-
-
Patel, T.1
Gores, G.J.2
-
153
-
-
0029784760
-
The peroxisome-proliferator-activated receptor alpha is a phosphoprotein: Regulation by insulin
-
Shalev A, Siegristkaiser CA, Yen PM, Wahli W, Burger AG, Chin WW, Meier CA. The peroxisome-proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin. Endocrinology 137:4499-4502 (1996).
-
(1996)
Endocrinology
, vol.137
, pp. 4499-4502
-
-
Shalev, A.1
Siegristkaiser, C.A.2
Yen, P.M.3
Wahli, W.4
Burger, A.G.5
Chin, W.W.6
Meier, C.A.7
-
154
-
-
0028092154
-
Apoptosis: Molecular control point in toxicity
-
Corcoran GB, Fix L, Jones DP, Moslen MT, Nicotera P, Oberhammer FA, Buttyan R. Apoptosis: molecular control point in toxicity. Toxicol Appl Pharmacol 128:169-181 (1994).
-
(1994)
Toxicol Appl Pharmacol
, vol.128
, pp. 169-181
-
-
Corcoran, G.B.1
Fix, L.2
Jones, D.P.3
Moslen, M.T.4
Nicotera, P.5
Oberhammer, F.A.6
Buttyan, R.7
-
155
-
-
0028102003
-
Regulation of apoptosis by low serum in cells of different stages of neoplastic progression: Enhanced susceptibility after loss of senescence gene and decreased susceptibility after loss of a tumor suppressor gene
-
Preston GA, Lang JE, Maronpot RR, Barrett JC. Regulation of apoptosis by low serum in cells of different stages of neoplastic progression: enhanced susceptibility after loss of senescence gene and decreased susceptibility after loss of a tumor suppressor gene. Cancer Res 52:4214-4223 (1994).
-
(1994)
Cancer Res
, vol.52
, pp. 4214-4223
-
-
Preston, G.A.1
Lang, J.E.2
Maronpot, R.R.3
Barrett, J.C.4
-
156
-
-
0026316216
-
Genetic errors, cell proliferation, and carcinogenesis
-
Cohen SM, Elwein LB. Genetic errors, cell proliferation, and carcinogenesis. Cancer Res 51:6493-6505 (1991).
-
(1991)
Cancer Res
, vol.51
, pp. 6493-6505
-
-
Cohen, S.M.1
Elwein, L.B.2
-
157
-
-
0026576029
-
Multistage carcinogenesis: Population-based model for colon cancer
-
Moolgavkar S, Luebeck G. Multistage carcinogenesis: population-based model for colon cancer. J Natl Cancer Inst 84:610-618 (1992).
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 610-618
-
-
Moolgavkar, S.1
Luebeck, G.2
-
158
-
-
0025963872
-
Analysis of cancer incidence data on the basis of multistage and clonal growth models
-
Stein WD. Analysis of cancer incidence data on the basis of multistage and clonal growth models. Adv Cancer Res 56:161-213 (1991).
-
(1991)
Adv Cancer Res
, vol.56
, pp. 161-213
-
-
Stein, W.D.1
-
160
-
-
0030915471
-
Inherent increase of apoptosis in liver tumors: Implications for carcinogenesis and tumor progression
-
Grasl-Kraupp B, Ruttkay-Nedecky R, Mullauer L, Taper H, Huber W, Bursch W, Schulte-Hermann R. Inherent increase of apoptosis in liver tumors: implications for carcinogenesis and tumor progression. Hepatology 25:906-912 (1997).
-
(1997)
Hepatology
, vol.25
, pp. 906-912
-
-
Grasl-Kraupp, B.1
Ruttkay-Nedecky, R.2
Mullauer, L.3
Taper, H.4
Huber, W.5
Bursch, W.6
Schulte-Hermann, R.7
-
161
-
-
0027960682
-
Ras proto-oncogene activation in dichloroacetic acid-, trichloroethylene-and tetrachloroethylene-induced liver tumors in B6C3F1 mice
-
Anna CH, Maronpot RR, Pereira MA, Foley JF, Malarkey DE, Anderson MW. Ras proto-oncogene activation in dichloroacetic acid-, trichloroethylene-and tetrachloroethylene-induced liver tumors in B6C3F1 mice. Carcinogenesis 15(10):2255-2261 (1994).
-
(1994)
Carcinogenesis
, vol.15
, Issue.10
, pp. 2255-2261
-
-
Anna, C.H.1
Maronpot, R.R.2
Pereira, M.A.3
Foley, J.F.4
Malarkey, D.E.5
Anderson, M.W.6
-
162
-
-
0029098336
-
Mutations in the ras proto-oncogene: Clues to etiology and molecular pathogenesis of mouse liver tumors
-
Maronpot RR, Fox T, Malarkey DE, Goldsworthy TL. Mutations in the ras proto-oncogene: clues to etiology and molecular pathogenesis of mouse liver tumors. Toxicology 101(3):125-156 (1995).
-
(1995)
Toxicology
, vol.101
, Issue.3
, pp. 125-156
-
-
Maronpot, R.R.1
Fox, T.2
Malarkey, D.E.3
Goldsworthy, T.L.4
-
163
-
-
0029163291
-
Hepatic and pulmonary carcinogenicity of methylene chloride in mice: A search for mechanisms
-
Maronpot RR, Devereux TR, Hegi M, Foley JF, Kanno J, Wiseman R, Anderson MW. Hepatic and pulmonary carcinogenicity of methylene chloride in mice: a search for mechanisms. Toxicology 102(1-2):73-81 (1995).
-
(1995)
Toxicology
, vol.102
, Issue.1-2
, pp. 73-81
-
-
Maronpot, R.R.1
Devereux, T.R.2
Hegi, M.3
Foley, J.F.4
Kanno, J.5
Wiseman, R.6
Anderson, M.W.7
-
164
-
-
0031428464
-
Dichloroacetic acid reduces Ha-ras codon 61 mutations in liver tumors from female B6C3F1 mice
-
Schroeder M, DeAngelo AB, Mass MJ. Dichloroacetic acid reduces Ha-ras codon 61 mutations in liver tumors from female B6C3F1 mice. Carcinogenesis 18(8):1675-1678 (1997).
-
(1997)
Carcinogenesis
, vol.18
, Issue.8
, pp. 1675-1678
-
-
Schroeder, M.1
DeAngelo, A.B.2
Mass, M.J.3
-
165
-
-
0030900929
-
Renal cell carcinomas in trichloroethene (TRI) exposed persons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumor suppressor gene
-
Bruning T, Weirich G, Hornauer MA, Hofler H, Brauch H. Renal cell carcinomas in trichloroethene (TRI) exposed persons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumor suppressor gene. Arch Toxicol 71(5):332-335 (1997).
-
(1997)
Arch Toxicol
, vol.71
, Issue.5
, pp. 332-335
-
-
Bruning, T.1
Weirich, G.2
Hornauer, M.A.3
Hofler, H.4
Brauch, H.5
-
166
-
-
0033583793
-
Trichloroethylene exposure and specific somatic mutations in patients with renal cell carcinoma
-
Brauch H, Weirich G, Hornauer MA, Storkel S, Wohl T, Bruning T. Trichloroethylene exposure and specific somatic mutations in patients with renal cell carcinoma. J Natl Cancer Inst 91(10):854-861 (1999).
-
(1999)
J Natl Cancer Inst
, vol.91
, Issue.10
, pp. 854-861
-
-
Brauch, H.1
Weirich, G.2
Hornauer, Ma.3
Storkel, S.4
Wohl, T.5
Bruning, T.6
-
167
-
-
0343122383
-
-
Personal communication
-
DeAngelo AB. Personal communication.
-
-
-
DeAngelo, A.B.1
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