Dichloroacetate (DCA) dosimetry: Interpreting DCA-induced liver cancer dose response and the potential for DCA to contribute to trichloroethylene-induced liver cancer

Toxicology Letters

Volumn 106, Issue 1, 1999, Pages 9-21

  Barton, Hugh A ^a   Bull, Richard ^b   Schultz, Irvin ^b   Andersen, Melvin E ^a  

^a KS Crump Group   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

Dichloroacetate; Mouse liver cancer; Pharmacokinetics; Trichloroethylene

Indexed keywords

DICHLOROACETIC ACID; TRICHLOROETHYLENE;

ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG INTERACTION; DRUG METABOLISM; LIVER CARCINOGENESIS; MALE; MOUSE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL;

ANIMALS; DICHLOROACETATE; DOSE-RESPONSE RELATIONSHIP, DRUG; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; TRICHLOROETHYLENE;

ANIMALIA; ZEA MAYS;

EID: 0032940898     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00016-8     Document Type: Article

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