Haloacetate-induced oxidative damage to DNA in the liver of male B6C3F1 mice

Toxicology

Volumn 110, Issue 1-3, 1996, Pages 103-111

  Parrish, Jeff M ^a   Austin, E W ^a,c   Stevens, D K ^a   Kinder, D H ^b   Bull, R J ^a,c  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b OHIO NORTHERN UNIVERSITY   (United States)

^c PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

8 Hydroxyguanosine; Chlorinated and brominated haloacetates; Peroxisome proliferation

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CLOFIBRIC ACID; DICHLOROACETIC ACID; LAURIC ACID; PEROXISOME PROLIFERATOR; TRICHLOROACETIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; LIVER CARCINOGENESIS; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALIA; RODENTIA;

EID: 0029890311     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0300-483X(96)03342-2     Document Type: Article

References (23)

1. Austin, E.W., Okita, J.R., Okita, R.T., Larson, J.L. and Bull, R.J. (1995) Modification of lipoperoxidative effects of dichloroacetate and trichloroacetate is associated with peroxisome proliferation. Toxicology 97, 59-69.
2. Austin, E.W., Parrish, J.M., Kinder, D.H. and Bull, R.J. (1996) Lipid peroxidation and formation of 8-hydroxydeoxyguanosine from acute doses of halogenated acetic acids. Fundam. Appl. Toxicol. 31, 77-82.
3. Bessho, T., Roy, R., Yamamoto, K., Kasai, H., Nishimura, S., Tano, K. and Mitra, S. (1993) Repair of 8-hydroxyguanine in DNA by mammalian N-methylpurine-DNA-glycosylase. Proc. Natl. Acad. Sci. USA 90, 8901-8904.
4. Bull, R.J., Sanchez, I.M., Nelson, M.A., Larson, J.L. and Lansing, A.J. (1990) Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate. Toxicology 69, 49-58.
5. Cattley, R.C. and Glover, S.E. (1993) Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: relationship to carcinogenesis and nuclear localization. Carcinogenesis 14, 2495-2499.
6. Clayclamp, H.G. (1992) Phenol sensitization of DNA to subsequent oxidative damage in 8-hydroxydeoxyguanosine assays. Carcinogenesis 13, 1289-1292.
7. Daniel, B.F., DeAngelo, A., Stober, J.A., Olson, G.R. and Page, N. P. (1992) Hepatocarcinogenicity of chloral hydrate, 2-chloroacetaldehyde, and dichloroacetic acid in the male B6C3F1 mouse. Fundam. Appl. Toxicol. 19, 159-168.
8. DeAngelo, A.B., Daniel, F.B., McMillan, L., Wernsing, P. and Savage, R.E. J. (1989) Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acids. Toxicol. Appl. Pharmacol. 101, 285-298.
9. Estabrook, R.W. and Werringloer, J. (1978) The measurement of difference spectra: application to the cytochromes of microsomes. Methods Enzymol. 52, 212-220.
10. Floyd, R.A., Watson, J.J., Wong, P.K., Altmiller, D.H. and Rickard, R.C. (1986) Hydroxyl free radical adduct of deoxyguanosine: sensitive detection and mechanisms of formation. Free Radic. Res. Commun. 1, 163-172.
11. Herren-Freund, S.L., Pereira, M.A., Khoury, M.D. and Olson, G. (1987) The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver. Toxicol. Appl. Pharmacol. 90, 183-189.
12. Kasai, H. and Nishimura, S. (1984) Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents. Nucleic Acids Res. 12, 2137-2145.
13. Kasai, H., Crain, P.F., Kuchino, Y., Nishimura, S., Ootsuyama, A. and Tanooka, H. (1986) Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis 7, 1849-1851.
14. Kasai, H., Okada, Y., Nishimura, S., Rao, M.S. and Reddy, J.K. (1989) Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator. Cancer Res. 49, 2603-2605.
15. Larson, J.L. and R.J. Bull, (1992) Metabolism and lipoperoxidative activity of trichloroacetate and dichloroacetate in rats and mice. Toxicol. Appl. Pharmacol. 115, 268-277.
16. Lazarow, P.B. and de Duve, C. (1976) A fatty-acyl-CoA oxidizing system in rat liver peroxisomes: enhancement by clofibrate, a hypolipidemic drug. Proc. Natl. Acad. Sci. USA 73, 2043-2046.
17. Lynch, W.W., Brown, R.F., Umeda, T., Langreth, S.G. and Lieberman, I. (1970) Synthesis of deoxyribonucleic acid by isolated liver nuclei. J. Biol. Chem. 245, 3911-3916.
18. Marmur, J. (1961) A procedure for the isolation of deoxyribonucleic acid from micro-organisms. J. Mol. Biol. 3, 208-218.
19. Okita, R.T., Castle, P.I. and Okita, J.R. (1993) Characterization of cytochromes P450 in liver and kidney of rats treated with di-(2-ethylhexyl)pthalate. J. Biochem. Toxicol. 8, 135-144.
20. Okita, R.T. and Okita, J.O. (1992) Characterization of a cytochrome P450 from di(2-ethylhexyl)phthalate-treated rats which hydroxylates fatty acids. Arch. Biochem. Biophys. 294, 475-481.
21. Takagi, A., Sai, K., Umemura, T., Hasegawa, R. and Kurokawa, Y. (1990a) Relationship between hepatic peroxisome proliferation and 8-hydroxydeoxyguanosine formation in liver DNA of rats following long-term exposure to three peroxisome proliferators: di(2-ethylhexyl)-phthalate, aluminium clofibrate and simfibrate. Cancer Lett. 53, 33-38.
22. Takagi, A., Sai, K., Umemura, T., Hasegawa, R. and Kurokawa, Y. (1990b) Significant increase of 8-hydroxydeoxyguanosine in liver DNA of rats following short-term exposure to the peroxisome proliferators di(2-ethylhexyl)phthalate and di(2-ethylhexyl)adipate. Jpn. J. Cancer Res. 81, 213-215.
23. Takagi, A., Sai, K., Umemura, T., Hasegawa, R. and Kurokawa, Y. (1991) Short-term exposure to the peroxisome proliferators, perfluorooctanoic acid and perfluorodecanoic acid, causes significant increase of 8-hydroxydeoxyguanosine in liver DNA of rats. Cancer Lett. 57, 55-60.