Loss of heterozygosity on chromosome 6 in dichloroacetic acid and trichloroacetic acid-induced liver tumors in female B6C3F1 mice

Cancer Letters

Volumn 108, Issue 2, 1996, Pages 257-261

  Tao, Lianhui ^a   Li, Kewa ^a   Kramer, Paula M ^a   Pereira, Michael A ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Alleles; Dichloroacetic acid; Loss of heterozygosity; Mouse liver tumors; Trichloroacetic acid

Indexed keywords

DICHLOROACETIC ACID; METHYLNITROSOUREA; TRICHLOROACETIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER GENETICS; CHEMICAL CARCINOGENESIS; CHROMOSOME 6; CONTROLLED STUDY; FEMALE; GENE LOSS; HETEROZYGOSITY LOSS; LIVER CARCINOGENESIS; LIVER TUMOR; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CHROMOSOME DELETION; DICHLOROACETATE; FEMALE; HUMANS; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; TRICHLOROACETIC ACID;

ANIMALIA;

EID: 0030606222     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(96)04451-5     Document Type: Article

References (21)

1. [1] Bruckner, J.V., Davis, B.D. and Blancato, J.N. (1989) Metabolism, toxicity, and carcinogenicity of trichloroethylene, CRC Crit. Rev. Toxicol.,, 20, 31-50.
2. [2] Ware, G.W. (1988) Tetrachloroethylene. Rev. Environ. Contam. Toxicol., 106, 175-188.
3. [3] Elcombe, C.R., Rose, M.S. and Pratt, I.S. (1985) Biochemical, histological, and ultrastructural changes in rat and mouse liver following the administration of trichloroethylene: possible relevance to species differences in hepatocarcinogenicity, Toxicol. Appl. Pharmacol., 79, 365-376.
4. [4] Uden, P.C. and Miller, J.W. (1983) Chlorinated acids and chloral in drinking water, J. Am. Water Works Assoc., 75, 524-527.
5. [5] Krasner, S.W., McGuire, M.J., Jacangelo, J.G., Patania, N.L., Reagen, K.M. and Ajeta. E.M. (1989) The occurrence of disinfection by-products in U.S. drinking water, J. Am. Water Works Assoc., 81, 41-53.
6. [6] Miller, J.W. and Uden, P.C. (1983) Characterization of non-volatile aqueous chlorination products of humic substances, Environ. Sci. Technol., 17, 150-157.
7. [7] Coleman, E.W., Munch, J.W., Kaylor, W.H., Streicher, R.P., Ringhand, H.P. and Meier, J.R. (1984) Gas chromatography/ mass spectroscopy analysis of mutagenic extracts of aqueous chlorinated humic acid. A comparison of the byproducts to drinking water contaminants. Environ. Sci. Technol., 18, 674-678.
8. [8] Goldsworthy, T.L. and Popp, J.A. (1987) Chlorinated hydrocarbon-induced peroxisomal enzyme activity in relation to species and organ carcinogenicity, Toxicol. Appl. Pharmacol., 88, 225-233.
9. [9] Odum, J., Green, T., Foster, J.R. and Hext, P.M. (1988) The role of trichloroacetic acid and peroxisome proliferation in the differences in carcinogenicity of perchloroethylene in the mouse and rat, Toxicol. Appl. Pharmacol., 92, 103-112.
10. [10] Herren-Freund, S.L., Pereira, M.A., Khoury, M.D. and Olson, G. (1987) The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic acid and dichloroacetic acid, in mouse liver, Toxicol, Appl. Pharmacol., 90, 183-189.
11. [11] Bull, R.J., Sanchez, I.M., Nelson, M.A., Larson, J.L. and Lansing, A.J. (1990) Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate, Toxicology, 63, 341-359.
12. [12] DeAngelo, A.B., Daniel, F.B., Stober, J.A. and Olson, G.R. (1991) The carcinogenicity of dichloroacetic acid in the male B6C3F1 mouse, Fundam. Appl. Toxicol., 16, 337-347.
13. [13] Pereira, M.A. (1996) Carcinogenic activity of dichloroacetic acid and trichloroacetic acid in the liver of female B6C3F1 mice, Fundam. Appl. Toxicol., 31, 192-199.
14. [14] Pereira, M.A. and Phelps, J.B. (1996) Promotion by dichloroacetic acid and trichloroacetic acid of N-methyl-N-nitrosourea-initiated cancer in the liver of female B6C3F1 mice, Cancer Lett., 102, 133-141.
15. [15] Anna, C.H., Maronpot, R.R., Pereira, M.A., Foley, J.F., Malarkey, D.E. and Anderson, M.W. (1994) Ras proto-oncogene activation in dichloroacetic acid-, trichloroethylene-and tetrachloroethylene-induced liver tumors in B6C3F1 mice, Carcinogenesis, 15, 2255-2261.
16. [16] Ferreira-Gonzalez, A., DeAngelo, A.B., Nasim, S. and Garrett, C.T. (1995) Ras oncogene activation during hepatocarcinogenesis in B6C3F1 male mice by dichloroacetic acid and trichloroacetic acid, Carcinogenesis, 16, 495-500.
17. [17] Davis, L.M., Caspary, W.J., Shakallah, S.A., Maronpot, R., Wiseman, R., Barrett, J.C., Elliott, R. and Hozier, J.C. (1994) Loss of heterozygosity in spontaneous and chemically induced tumors of B6C3F1 mouse, Carcinogenesis, 15, 1637-1645.
18. [18] Ward, J.M., Rice, J.M., Creasia, D., Lynch, P. and Riggs, C. (1983) Dissimilar patterns of promotion by di(2-ethylhexyl)phthalate and phenobarbital of hepatocellular neoplasia initiated by diethylnitrosamine in B6C3F1 mice, Carcinogenesis, 4, 1021-1029.
19. [19] Chomczynski, P. (1993) A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples, Biotechniques, 15, 532-535.
20. [20] Copeland, N.G., Jenkins, N.A. and Gilberg, D.J. (1993) A genetic linkage map of the mouse: current applications and future prospects, Science, 262, 57-66.
21. [21] Marsman, D.S. and Popp, J.A. (1994) Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643, Carcinogenesis, 15, 111-117.