Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human

Nature Genetics

Volumn 26, Issue 1, 2000, Pages 44-50

  Huynh, Duong P ^a   Figueroa, Karla ^a   Hoang, Nam ^a   Pulst, Stefan M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIN 2; DNA; MUTANT PROTEIN; POLYGLUTAMINE; UNCLASSIFIED DRUG;

ARTICLE; BRAIN CELL; CELL CULTURE; CELL LOSS; CELL NUCLEUS INCLUSION BODY; CYTOPLASM; DEGENERATIVE DISEASE; HUMAN; IMMUNOHISTOCHEMISTRY; MOUSE; MUTATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PURKINJE CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINOCEREBELLAR ATAXIA TYPE 2; TRANSGENIC MOUSE; TRINUCLEOTIDE REPEAT;

ANIMALS; BLOTTING, WESTERN; BRAIN; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; CELL LINE; CELL NUCLEUS; CEREBELLUM; CYTOPLASM; EXERCISE TEST; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INCLUSION BODIES; LUMINESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MODELS, GENETIC; MUTATION; NERVE TISSUE PROTEINS; PEPTIDES; PHYSICAL CONDITIONING, ANIMAL; PROTEIN BIOSYNTHESIS; PROTEINS; PURKINJE CELLS; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SPINOCEREBELLAR ATAXIAS; TIME FACTORS; TRANSGENES; UBIQUITINS;

ATAXIA; MUS MUSCULUS;

EID: 0033811788     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/79162     Document Type: Article

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