-
3
-
-
0024580323
-
Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma
-
Kasid U., Pfeifer A., Brennan T., Beckett M., Weichselbaum R. R., Dritschilo A., Mark G. E. Effect of antisense c-raf-1 on tumorigenicity and radiation sensitivity of a human squamous carcinoma. Science. 243:1989;1354-1356.
-
(1989)
Science
, vol.243
, pp. 1354-1356
-
-
Kasid, U.1
Pfeifer, A.2
Brennan, T.3
Beckett, M.4
Weichselbaum, R.R.5
Dritschilo, A.6
Mark, G.E.7
-
4
-
-
0028838446
-
Dominant oncogenes, tumor suppressors, and radiosensitivity
-
Chiarugi V., Magnelli L., Cinelli M., Turchetti A., Ruggiero M. Dominant oncogenes, tumor suppressors, and radiosensitivity. Cell. Mol. Biol. Res. 41:1995;161-166.
-
(1995)
Cell. Mol. Biol. Res.
, vol.41
, pp. 161-166
-
-
Chiarugi, V.1
Magnelli, L.2
Cinelli, M.3
Turchetti, A.4
Ruggiero, M.5
-
5
-
-
0028233618
-
C-raf-1 proto-oncogene expression relates to radiosensitivity rather than radioresistance
-
Warenius H. M., Browning P. G., Britten R. A., Peacock J. A., Rapp U. R. C-raf-1 proto-oncogene expression relates to radiosensitivity rather than radioresistance. Eur. J. Cancer. 30A:1994;369-375.
-
(1994)
Eur. J. Cancer
, vol.30
, pp. 369-375
-
-
Warenius, H.M.1
Browning, P.G.2
Britten, R.A.3
Peacock, J.A.4
Rapp, U.R.5
-
6
-
-
0025820386
-
Radiosensitivity of small-cell lung cancer xenografts compared with activity of c-myc, N-myc, L-myc, c-raf-1 and K-ras proto-oncogenes
-
Rygaard K., Slebos R. J., Spang-Thomsen M. Radiosensitivity of small-cell lung cancer xenografts compared with activity of c-myc, N-myc, L-myc, c-raf-1 and K-ras proto-oncogenes. Int. J. Cancer. 49:1991;279-284.
-
(1991)
Int. J. Cancer
, vol.49
, pp. 279-284
-
-
Rygaard, K.1
Slebos, R.J.2
Spang-Thomsen, M.3
-
7
-
-
0030836807
-
Response to radiotherapy of human uterine cervix carcinoma is not correlated with rearrangements of the Ha-ras-1 and/or c-myc genes
-
Polischouk A. G., Scotnikova O. I., Sergeeva N. S., Zharinov G. M., Lewensohn R., Zhivotovsky B. Response to radiotherapy of human uterine cervix carcinoma is not correlated with rearrangements of the Ha-ras-1 and/or c-myc genes. Eur. J. Cancer. 33:1997;942-949.
-
(1997)
Eur. J. Cancer
, vol.33
, pp. 942-949
-
-
Polischouk, A.G.1
Scotnikova, O.I.2
Sergeeva, N.S.3
Zharinov, G.M.4
Lewensohn, R.5
Zhivotovsky, B.6
-
9
-
-
0032575705
-
A matter of life and cell death
-
Evan G., Littlewood T. A matter of life and cell death. Science. 281:1998;1317-1322.
-
(1998)
Science
, vol.281
, pp. 1317-1322
-
-
Evan, G.1
Littlewood, T.2
-
11
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr J. F., Wyllie A. H., Currie A. R. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer. 26:1972;239-257.
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
12
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson C. B. Apoptosis in the pathogenesis and treatment of disease. Science. 267:1995;1456-1462.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
15
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry N. A., Lazebnik Y. Caspases: Enemies within. Science. 281:1998;1312-1316.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
16
-
-
0031615875
-
Autoproteolytic activation of pro-caspases by oligomerization
-
Yang X., Chang H. Y., Baltimore D. Autoproteolytic activation of pro-caspases by oligomerization. Mol. Cell. 1:1998;319-325.
-
(1998)
Mol. Cell
, vol.1
, pp. 319-325
-
-
Yang, X.1
Chang, H.Y.2
Baltimore, D.3
-
17
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P., Nijhawan D., Budihardjo I., Srinivasula S. M., Ahmad M., Alnemri E. S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91:1997;479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
19
-
-
0032409781
-
Bcl-2 family proteins
-
Reed J. C. Bcl-2 family proteins. Oncogene. 17:1998;325-336.
-
(1998)
Oncogene
, vol.17
, pp. 325-336
-
-
Reed, J.C.1
-
20
-
-
0030916669
-
The proto-oncogene Bcl-2 and its role in regulating apoptosis
-
Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med. 3:1997;614-620.
-
(1997)
Nat. Med.
, vol.3
, pp. 614-620
-
-
Kroemer, G.1
-
21
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expressionin vitroin vivo
-
Miyashita T., Krajewski S., Krajewska M., Wang H. G., Lin H. K., Liebermann D. A., Hoffman B., Reed J. C. Tumor suppressor p53 is a regulator of bcl-2 and bax gene expressionin vitroin vivo. Oncogene. 9:1994;1799-1805.
-
(1994)
Oncogene
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewska, M.3
Wang, H.G.4
Lin, H.K.5
Liebermann, D.A.6
Hoffman, B.7
Reed, J.C.8
-
22
-
-
0027109075
-
Cancer. p53, guardian of the genome
-
Lane D. P. Cancer. p53, guardian of the genome. Nature. 358:1992;15-16.
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
23
-
-
0019416621
-
Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy
-
Fertil B., Malaise E. P. Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 7:1981;621-629.
-
(1981)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.7
, pp. 621-629
-
-
Fertil, B.1
Malaise, E.P.2
-
24
-
-
0027486745
-
Heterogeneity in the development of apoptosis in irradiated murine tumours of different histologies
-
Meyn R. E., Stephens L. C., Ang K. K., Hunter N. R., Brock W. A., Milas L., Peters L. J. Heterogeneity in the development of apoptosis in irradiated murine tumours of different histologies. Int. J. Radiat. Biol. 64:1993;583-591.
-
(1993)
Int. J. Radiat. Biol.
, vol.64
, pp. 583-591
-
-
Meyn, R.E.1
Stephens, L.C.2
Ang, K.K.3
Hunter, N.R.4
Brock, W.A.5
Milas, L.6
Peters, L.J.7
-
25
-
-
0030871780
-
Apoptosis: An indicator of radiosensitivityin vitro?
-
Olive P. L., Durand R. E. Apoptosis: An indicator of radiosensitivityin vitro? Int. J. Radiat. Biol. 71:1997;695-707.
-
(1997)
Int. J. Radiat. Biol.
, vol.71
, pp. 695-707
-
-
Olive, P.L.1
Durand, R.E.2
-
26
-
-
0029100685
-
ASTRO Research Fellowship: Apoptosis as a predictor of tumor response to radiation in stage IB cervical carcinoma
-
Wheeler J. A., Stephens L. C., Tornos C., Eifel P. J., Ang K. K., Milas L., Allen P. K., Meyn R. E. Jr. ASTRO Research Fellowship: Apoptosis as a predictor of tumor response to radiation in stage IB cervical carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 32:1995;1487-1493.
-
(1995)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.32
, pp. 1487-1493
-
-
Wheeler, J.A.1
Stephens, L.C.2
Tornos, C.3
Eifel, P.J.4
Ang, K.K.5
Milas, L.6
Allen, P.K.7
Meyn R.E., Jr.8
-
27
-
-
0031839519
-
Spontaneous and radiation-induced apoptosis in lung carcinoma cells with different intrinsic radiosensitivities
-
Sirzen F., Zhivotovsky B., Nilsson A., Bergh J., Lewensohn R. Spontaneous and radiation-induced apoptosis in lung carcinoma cells with different intrinsic radiosensitivities. Anticancer Res. 18:1998;695-699.
-
(1998)
Anticancer Res.
, vol.18
, pp. 695-699
-
-
Sirzen, F.1
Zhivotovsky, B.2
Nilsson, A.3
Bergh, J.4
Lewensohn, R.5
-
28
-
-
0028860378
-
Apoptosis, intrinsic radiosensitivity and prediction of radiotherapy response in cervical carcinoma
-
Levine E. L., Renehan A., Gossiel R., Davidson S. E., Roberts S. A., Chadwick C., Wilks D. P., Potten C. S., Hendry J. H., Hunter R. D., West C. M. L. Apoptosis, intrinsic radiosensitivity and prediction of radiotherapy response in cervical carcinoma. Radiother. Oncol. 37:1995;1-9.
-
(1995)
Radiother. Oncol.
, vol.37
, pp. 1-9
-
-
Levine, E.L.1
Renehan, A.2
Gossiel, R.3
Davidson, S.E.4
Roberts, S.A.5
Chadwick, C.6
Wilks, D.P.7
Potten, C.S.8
Hendry, J.H.9
Hunter, R.D.10
West, C.M.L.11
-
29
-
-
0031298054
-
In vitro
-
Dubray B., Breton C., Delic J., Klijanienko J., Maciorowski Z., Vielh P., Fourquet A., Dumont J., Magdelenat H., Cosset J. M. In vitro. Int. J. Radiat. Biol. 72:1997;759-760.
-
(1997)
Int. J. Radiat. Biol.
, vol.72
, pp. 759-760
-
-
Dubray, B.1
Breton, C.2
Delic, J.3
Klijanienko, J.4
Maciorowski, Z.5
Vielh, P.6
Fourquet, A.7
Dumont, J.8
Magdelenat, H.9
Cosset, J.M.10
-
30
-
-
0032126541
-
Explaining differences in sensitivity to killing by ionizing radiation between human lymphoid cell lines
-
Aldridge D. R., Radford I. R. Explaining differences in sensitivity to killing by ionizing radiation between human lymphoid cell lines. Cancer Res. 58:1998;2817-2824.
-
(1998)
Cancer Res.
, vol.58
, pp. 2817-2824
-
-
Aldridge, D.R.1
Radford, I.R.2
-
31
-
-
0032191676
-
Higher spontaneous apoptotic index in small-cell compared with non-small-cell lung carcinoma cell lines: Lack of correlation with Bcl-2/Bax
-
Sirzen F., Zhivotovsky B., Nilsson A., Bergh J., Lewenshon R. Higher spontaneous apoptotic index in small-cell compared with non-small-cell lung carcinoma cell lines: Lack of correlation with Bcl-2/Bax. Lung Cancer. 22:1998;1-13.
-
(1998)
Lung Cancer
, vol.22
, pp. 1-13
-
-
Sirzen, F.1
Zhivotovsky, B.2
Nilsson, A.3
Bergh, J.4
Lewenshon, R.5
-
32
-
-
0027319521
-
P53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe S. W., Shmitt E. M., Smith S. W., Osborne B. A., Jacks J. P53 is required for radiation-induced apoptosis in mouse thymocytes. Nature. 362:1993;847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Shmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, J.5
-
33
-
-
0027258466
-
Thymocytes apoptosis induced by p53-dependent and independent pathways
-
Clarke A. R., Purdie C. A., Harrison D. J., Morris R. G., Bird C. C., Hooper M. L., Wyllie A. H. Thymocytes apoptosis induced by p53-dependent and independent pathways. Nature. 362:1993;849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
34
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
el-Deiry W. S., Tokino T., Velculescu V. E., Levy D. B., Parsons R., Trent J. M., Lin D., Mercer W. E., Kinzler K. W., Vogelstein B. WAF1, a potential mediator of p53 tumor suppression. Cell. 75:1993;817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
35
-
-
0031672216
-
Role of p53 mutations in the radiosensitivity status of tumor cells
-
Chiarugi V., Magnelli L., Cinelli M. Role of p53 mutations in the radiosensitivity status of tumor cells. Tumori. 84:1998;517-520.
-
(1998)
Tumori
, vol.84
, pp. 517-520
-
-
Chiarugi, V.1
Magnelli, L.2
Cinelli, M.3
-
36
-
-
0031471671
-
P53-independent response of a human breast carcinoma xenograft to radioimmunotherapy
-
Winthrop M. D., DeNardo S. J., Muenzer J. T., Chi S. G., Gumerlock P. H. p53-independent response of a human breast carcinoma xenograft to radioimmunotherapy. Cancer. 80:1997;2529-2537.
-
(1997)
Cancer
, vol.80
, pp. 2529-2537
-
-
Winthrop, M.D.1
Denardo, S.J.2
Muenzer, J.T.3
Chi, S.G.4
Gumerlock, P.H.5
-
37
-
-
0031787083
-
P53- And p21-independent apoptosis of squamous cell carcinoma cells induced by 5-fluorouracil and radiation
-
Yoneda K., Yamamoto T., Osaki T. p53- and p21-independent apoptosis of squamous cell carcinoma cells induced by 5-fluorouracil and radiation. Oral Oncol. 34:1998;529-537.
-
(1998)
Oral Oncol.
, vol.34
, pp. 529-537
-
-
Yoneda, K.1
Yamamoto, T.2
Osaki, T.3
-
38
-
-
8044248976
-
Overexpression of bax enhances the radiation sensitivity in human breast cancer cells
-
Sakakura C., Sweeney E. A., Shirahama T., Igarashi Y., Hakomori S., Tsujimoto H., Imanishi T., Ohgaki M., Yamazaki J., Hagiwara A., Sawai K., Yamaguchi T., Takahashi T. Overexpression of bax enhances the radiation sensitivity in human breast cancer cells. Surg. Today. 27:1997;90-93.
-
(1997)
Surg. Today
, vol.27
, pp. 90-93
-
-
Sakakura, C.1
Sweeney, E.A.2
Shirahama, T.3
Igarashi, Y.4
Hakomori, S.5
Tsujimoto, H.6
Imanishi, T.7
Ohgaki, M.8
Yamazaki, J.9
Hagiwara, A.10
Sawai, K.11
Yamaguchi, T.12
Takahashi, T.13
-
40
-
-
0031669402
-
Bax and Bcl-2 expressions predict response to radiotherapy in human cervical cancer
-
Harima Y., Harima K., Shikata N., Oka A., Ohnishi T., Tanaka Y. Bax and Bcl-2 expressions predict response to radiotherapy in human cervical cancer. J. Cancer Res. Clin. Oncol. 124:1998;503-510.
-
(1998)
J. Cancer Res. Clin. Oncol.
, vol.124
, pp. 503-510
-
-
Harima, Y.1
Harima, K.2
Shikata, N.3
Oka, A.4
Ohnishi, T.5
Tanaka, Y.6
-
41
-
-
0032126465
-
Bax protein expression correlates with radiation-induced apoptosis in radiation therapy for cervical carcinoma
-
Ohno T., Nakano T., Niibe Y., Tsujii H., Oka K. Bax protein expression correlates with radiation-induced apoptosis in radiation therapy for cervical carcinoma. Cancer. 83:1998;103-110.
-
(1998)
Cancer
, vol.83
, pp. 103-110
-
-
Ohno, T.1
Nakano, T.2
Niibe, Y.3
Tsujii, H.4
Oka, K.5
-
42
-
-
0032076197
-
Expression of p53, p21/WAF/CIP, Bcl-2, Bax, Bcl-x, and Bak in radiation-induced apoptosis in testicular germ cell tumor lines
-
Burger H., Nooter K., Boersma A. W., Kortland C. J., van den Berg A. P., Stoter G. Expression of p53, p21/WAF/CIP, Bcl-2, Bax, Bcl-x, and Bak in radiation-induced apoptosis in testicular germ cell tumor lines. Int. J. Radiat. Oncol. Biol. Phys. 41:1998;415-424.
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.41
, pp. 415-424
-
-
Burger, H.1
Nooter, K.2
Boersma, A.W.3
Kortland, C.J.4
Van Den Berg, A.P.5
Stoter, G.6
-
43
-
-
0030812173
-
Radiation-induced apoptosis is not enhanced by expression of either p53 or BAX in SW626 ovarian cancer cells
-
Strobel T., Swanson L., Korsmeyer S., Cannistra S. A. Radiation-induced apoptosis is not enhanced by expression of either p53 or BAX in SW626 ovarian cancer cells. Oncogene. 14:1997;2753-2758.
-
(1997)
Oncogene
, vol.14
, pp. 2753-2758
-
-
Strobel, T.1
Swanson, L.2
Korsmeyer, S.3
Cannistra, S.A.4
-
44
-
-
0031754828
-
Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis
-
Peter M. E., Krammer P. H. Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis. Curr. Opin. Immunol. 10:1998;545-551.
-
(1998)
Curr. Opin. Immunol.
, vol.10
, pp. 545-551
-
-
Peter, M.E.1
Krammer, P.H.2
-
45
-
-
0030868999
-
Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1)
-
Rehemtulla A., Hamilton C. A., Chinnaiyan A. M., Dixit V. M. Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1). J. Biol. Chem. 272:1997;25783-25786.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25783-25786
-
-
Rehemtulla, A.1
Hamilton, C.A.2
Chinnaiyan, A.M.3
Dixit, V.M.4
-
46
-
-
0031803217
-
Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis
-
Caricchio R., Reap E. A., Cohen P. L. Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis. J. Immunol. 161:1998;241-251.
-
(1998)
J. Immunol.
, vol.161
, pp. 241-251
-
-
Caricchio, R.1
Reap, E.A.2
Cohen, P.L.3
-
47
-
-
0031943921
-
Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L
-
Aragane Y., Kulms D., Metze D., Wilkes G., Poppelmann B., Luger T. A., Schwarz T. Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L. J. Cell Biol. 140:1998;171-182.
-
(1998)
J. Cell Biol.
, vol.140
, pp. 171-182
-
-
Aragane, Y.1
Kulms, D.2
Metze, D.3
Wilkes, G.4
Poppelmann, B.5
Luger, T.A.6
Schwarz, T.7
-
48
-
-
0031835210
-
Radiation-induced apoptosis in human lymphocytes and lymphoma cells critically relies on the up-regulation of CD95/Fas/APO-1 ligand
-
Belka C., Marini P., Budach W., Schulze-Osthoff K., Lang F., Gulbins E., Bamberg M. Radiation-induced apoptosis in human lymphocytes and lymphoma cells critically relies on the up-regulation of CD95/Fas/APO-1 ligand. Radiat. Res. 149:1998;588-595.
-
(1998)
Radiat. Res.
, vol.149
, pp. 588-595
-
-
Belka, C.1
Marini, P.2
Budach, W.3
Schulze-Osthoff, K.4
Lang, F.5
Gulbins, E.6
Bamberg, M.7
-
49
-
-
0031588408
-
Up-regulation of Fas (CD95) in human p53 wild-type cancer cells treated with ionizing radiation
-
Sheard M. A., Vojtesek B., Janakova L., Kovarik J., Zaloudik J. Up-regulation of Fas (CD95) in human p53 wild-type cancer cells treated with ionizing radiation. Int. J. Cancer. 73:1997;757-762.
-
(1997)
Int. J. Cancer
, vol.73
, pp. 757-762
-
-
Sheard, M.A.1
Vojtesek, B.2
Janakova, L.3
Kovarik, J.4
Zaloudik, J.5
-
50
-
-
0030806351
-
Comparison of apoptosis in wild-type and Fas-resistant cells: Chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions
-
Eischen C. M., Kottke T. J., Martins L. M., Basi G. S., Tung J. S., Earnshaw W. C., Leibson P. J., Kaufmann S. H. Comparison of apoptosis in wild-type and Fas-resistant cells: Chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions. Blood. 90:1997;935-943.
-
(1997)
Blood
, vol.90
, pp. 935-943
-
-
Eischen, C.M.1
Kottke, T.J.2
Martins, L.M.3
Basi, G.S.4
Tung, J.S.5
Earnshaw, W.C.6
Leibson, P.J.7
Kaufmann, S.H.8
-
51
-
-
0031560955
-
Interleukin-1beta-converting enzyme and CPP32 are involved in ultraviolet B-induced apoptosis of SV40-transformed human keratinocytes
-
Takahashi H., Kinouchi M., Iizuka H. Interleukin-1beta-converting enzyme and CPP32 are involved in ultraviolet B-induced apoptosis of SV40-transformed human keratinocytes. Biochem. Biophys. Res. Commun. 236:1997;194-198.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.236
, pp. 194-198
-
-
Takahashi, H.1
Kinouchi, M.2
Iizuka, H.3
-
52
-
-
0032500793
-
Cell surface trafficking of Fas: A rapid mechanism of p53-mediated apoptosis
-
Bennett M., Macdonald K., Chan S. W., Luzio J. P., Simari R., Weissberg P. Cell surface trafficking of Fas: A rapid mechanism of p53-mediated apoptosis. Science. 282:1998;290-293.
-
(1998)
Science
, vol.282
, pp. 290-293
-
-
Bennett, M.1
Macdonald, K.2
Chan, S.W.3
Luzio, J.P.4
Simari, R.5
Weissberg, P.6
-
54
-
-
0028537064
-
The sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor, Fas, and ionizing radiation
-
Kolesnick R. N., Haimovitz-Friedman A., Fuks Z. The sphingomyelin signal transduction pathway mediates apoptosis for tumor necrosis factor, Fas, and ionizing radiation. Biochem. Cell Biol. 72:1994;471-474.
-
(1994)
Biochem. Cell Biol.
, vol.72
, pp. 471-474
-
-
Kolesnick, R.N.1
Haimovitz-Friedman, A.2
Fuks, Z.3
-
55
-
-
0028287960
-
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis
-
Haimovitz-Friedman A., Kan C. C., Ehleiter D., Persaud R. S., McLoughlin M., Fuks Z., Kolesnick R. N. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J. Exp. Med. 180:1994;525-535.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 525-535
-
-
Haimovitz-Friedman, A.1
Kan, C.C.2
Ehleiter, D.3
Persaud, R.S.4
McLoughlin, M.5
Fuks, Z.6
Kolesnick, R.N.7
-
56
-
-
0029965928
-
Tumor cell resistance to apoptosis due to a defect in the activation of sphingomyelinase and the 24 kDa apoptotic protease (AP24)
-
Wright S. C., Zheng H., Zhong J. Tumor cell resistance to apoptosis due to a defect in the activation of sphingomyelinase and the 24 kDa apoptotic protease (AP24). FASEB J. 10:1996;325-332.
-
(1996)
FASEB J.
, vol.10
, pp. 325-332
-
-
Wright, S.C.1
Zheng, H.2
Zhong, J.3
-
57
-
-
16044364385
-
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis
-
Santana P., Pena L. A., Haimovitz-Friedman A., Martin S., Green D., McLoughlin M., Cordon-Cardo C., Schuchman E. H., Fuks Z., Kolesnick R. Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. Cell. 86:1996;189-199.
-
(1996)
Cell
, vol.86
, pp. 189-199
-
-
Santana, P.1
Pena, L.A.2
Haimovitz-Friedman, A.3
Martin, S.4
Green, D.5
McLoughlin, M.6
Cordon-Cardo, C.7
Schuchman, E.H.8
Fuks, Z.9
Kolesnick, R.10
-
58
-
-
0030945257
-
Loss of ceramide production confers resistance to radiation-induced apoptosis
-
Chmura S. J., Nodzenski E., Beckett M. A., Kufe D. W., Quintans J., Weichselbaum R. R. Loss of ceramide production confers resistance to radiation-induced apoptosis. Cancer Res. 57:1997;1270-1275.
-
(1997)
Cancer Res.
, vol.57
, pp. 1270-1275
-
-
Chmura, S.J.1
Nodzenski, E.2
Beckett, M.A.3
Kufe, D.W.4
Quintans, J.5
Weichselbaum, R.R.6
-
59
-
-
0030769389
-
Resistance to radiation-induced apoptosis in Burkitt's lymphoma cells is associated with defective ceramide signaling
-
Michael J. M., Lavin M. F., Watters D. J. Resistance to radiation-induced apoptosis in Burkitt's lymphoma cells is associated with defective ceramide signaling. Cancer Res. 57:1997;3600-3605.
-
(1997)
Cancer Res.
, vol.57
, pp. 3600-3605
-
-
Michael, J.M.1
Lavin, M.F.2
Watters, D.J.3
-
60
-
-
0031757668
-
Ceramide in apoptosis - Does it really matter?
-
Hofmann K., Dixit V. M. Ceramide in apoptosis - Does it really matter? Trends Biochem. Sci. 23:1998;374-377.
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 374-377
-
-
Hofmann, K.1
Dixit, V.M.2
-
61
-
-
0032577867
-
Role of ultraviolet A-induced DNA damage in apoptosis via loss of mitochondrial membrane potential and caspase-3 activation
-
Saeko T. O., Oikawa S., Kawanishi S. Role of ultraviolet A-induced DNA damage in apoptosis via loss of mitochondrial membrane potential and caspase-3 activation. Biochem. Biophys. Res. Commun. 247:1998;693-696.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.247
, pp. 693-696
-
-
Saeko, T.O.1
Oikawa, S.2
Kawanishi, S.3
-
62
-
-
0031799946
-
The morphological and spectral phenotype of apoptosis in HeLa cells varies following exposure to UV-C and the addition of inhibitors of ICE and CPP32
-
Miller M. L., Andringa A., Elliott J., Conwell K. II, Dixon K., Carty M. P. The morphological and spectral phenotype of apoptosis in HeLa cells varies following exposure to UV-C and the addition of inhibitors of ICE and CPP32. Cell Prolif. 31:1998;17-33.
-
(1998)
Cell Prolif.
, vol.31
, pp. 17-33
-
-
Miller, M.L.1
Andringa, A.2
Elliott, J.3
Conwell K. II4
Dixon, K.5
Carty, M.P.6
-
63
-
-
0032472329
-
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
-
Bossy-Wetzel E., Newmeyer D. D., Green D. R. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J. 17:1998;37-49.
-
(1998)
EMBO J.
, vol.17
, pp. 37-49
-
-
Bossy-Wetzel, E.1
Newmeyer, D.D.2
Green, D.R.3
-
64
-
-
0032548030
-
Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1
-
Sheikh M. S., Antinore M. J., Huang Y., Fornace A. J. Jr. Ultraviolet-irradiation-induced apoptosis is mediated via ligand independent activation of tumor necrosis factor receptor 1. Oncogene. 17:1998;2555-2563.
-
(1998)
Oncogene
, vol.17
, pp. 2555-2563
-
-
Sheikh, M.S.1
Antinore, M.J.2
Huang, Y.3
Fornace A.J., Jr.4
-
65
-
-
15144349717
-
Cytochrome c-dependent and -independent induction of apoptosis in multiple myeloma cells
-
Chauhan D., Pandey P., Ogata A., Teoh G., Krett N., Halgren R., Rosen S., Kufe D., Kharbanda S., Anderson K. Cytochrome c-dependent and -independent induction of apoptosis in multiple myeloma cells. J. Biol. Chem. 272:1997;29995-29997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29995-29997
-
-
Chauhan, D.1
Pandey, P.2
Ogata, A.3
Teoh, G.4
Krett, N.5
Halgren, R.6
Rosen, S.7
Kufe, D.8
Kharbanda, S.9
Anderson, K.10
-
66
-
-
0031440230
-
Involvement of ICE (caspase) family in gamma-radiation-induced apoptosis of normal B lymphocytes
-
Hallan E., Blomhoff H. K., Smeland E. B., Lomo J. Involvement of ICE (caspase) family in gamma-radiation-induced apoptosis of normal B lymphocytes. Scand. J. Immunol. 46:1997;601-608.
-
(1997)
Scand. J. Immunol.
, vol.46
, pp. 601-608
-
-
Hallan, E.1
Blomhoff, H.K.2
Smeland, E.B.3
Lomo, J.4
-
67
-
-
0032190057
-
P53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines
-
Yu Y., Little J. B. p53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines. Cancer Res. 58:1998;4277-4281.
-
(1998)
Cancer Res.
, vol.58
, pp. 4277-4281
-
-
Yu, Y.1
Little, J.B.2
-
68
-
-
0032143986
-
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
Varfolomeev E. E., Schuchmann M., Luria V., Chiannilkulchai N., Beckmann J. S., Mett I. L., Rebrikov D., Brodianski V. M., Kemper O. C., Kollet O., Lapidot T., Soffer D., Sobe T., Avraham K. B., Goncharov T., Holtmann H., Lonai P., Wallach D. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity. 9:1998;267-276.
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
Rebrikov, D.7
Brodianski, V.M.8
Kemper, O.C.9
Kollet, O.10
Lapidot, T.11
Soffer, D.12
Sobe, T.13
Avraham, K.B.14
Goncharov, T.15
Holtmann, H.16
Lonai, P.17
Wallach, D.18
-
69
-
-
15644364847
-
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
-
Woo M., Hakem R., Soengas M. S., Duncan G. S., Shahinian A., Kagi D., Hakem A., McCurrach M., Khoo W., Kaufman S. A., Senaldi G., Howard T., Lowe S. W., Mak T. W. Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev. 12:1998;806-819.
-
(1998)
Genes Dev.
, vol.12
, pp. 806-819
-
-
Woo, M.1
Hakem, R.2
Soengas, M.S.3
Duncan, G.S.4
Shahinian, A.5
Kagi, D.6
Hakem, A.7
McCurrach, M.8
Khoo, W.9
Kaufman, S.A.10
Senaldi, G.11
Howard, T.12
Lowe, S.W.13
Mak, T.W.14
-
70
-
-
0032493870
-
Differential requirement for caspase-9 in apoptotic pathwaysin vivo
-
Hakem R., Hakem A., Duncan G. S., Henderson J. T., Woo M., Soengas M. S., Elia A., de la Pompa J. L., Kagi D., Khoo W., Potter J., Yoshida R., Kaufman S. A., Lowe S. W., Penninger J. M., Mak T. W. Differential requirement for caspase-9 in apoptotic pathwaysin vivo. Cell. 94:1998;339-352.
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
Hakem, A.2
Duncan, G.S.3
Henderson, J.T.4
Woo, M.5
Soengas, M.S.6
Elia, A.7
De La Pompa, J.L.8
Kagi, D.9
Khoo, W.10
Potter, J.11
Yoshida, R.12
Kaufman, S.A.13
Lowe, S.W.14
Penninger, J.M.15
Mak, T.W.16
-
71
-
-
0032544268
-
Apoptotic pathways: The roads to ruin
-
Green D. R. Apoptotic pathways: The roads to ruin. Cell. 94:1998;695-698.
-
(1998)
Cell
, vol.94
, pp. 695-698
-
-
Green, D.R.1
-
72
-
-
0032506136
-
Oncogene-dependent apoptosis is mediated by caspase-9
-
Fearnhead H. O., Rodriguez J., Govek E. E., Guo W., Kobayashi R., Hannon G., Lazebnik Y. A. Oncogene-dependent apoptosis is mediated by caspase-9. Proc. Natl. Acad. Sci. USA. 95:1998;13664-13669.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13664-13669
-
-
Fearnhead, H.O.1
Rodriguez, J.2
Govek, E.E.3
Guo, W.4
Kobayashi, R.5
Hannon, G.6
Lazebnik, Y.A.7
-
73
-
-
0030938089
-
Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
-
McCurrach M. E., Connor T. M. F., Knudson C. M., Korsmeyer S. J., Lowe S. W. bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proc. Natl. Acad. Sci. USA. 94:1997;2345-2349.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2345-2349
-
-
McCurrach, M.E.1
Connor, T.M.F.2
Knudson, C.M.3
Korsmeyer, S.J.4
Lowe, S.W.5
-
74
-
-
0031038137
-
Bax suppresses tumorigenesis and stimulates apoptosisin vivo
-
Yin C., Knudson C. M., Korsmeyer S. J., Van Dyke T. Bax suppresses tumorigenesis and stimulates apoptosisin vivo. Nature. 385:1997;637-640.
-
(1997)
Nature
, vol.385
, pp. 637-640
-
-
Yin, C.1
Knudson, C.M.2
Korsmeyer, S.J.3
Van Dyke, T.4
-
75
-
-
0032535730
-
Blood cells with reduced mitochondrial membrane potential and cytosolic cytochrome c can survive and maintain clonogenicity given appropriate signals to suppress apoptosis
-
Chen Q., Takeyama N., Brady G., Watson A. J. M., Dive C. Blood cells with reduced mitochondrial membrane potential and cytosolic cytochrome c can survive and maintain clonogenicity given appropriate signals to suppress apoptosis. Blood. 92:1998;4545-4553.
-
(1998)
Blood
, vol.92
, pp. 4545-4553
-
-
Chen, Q.1
Takeyama, N.2
Brady, G.3
Watson, A.J.M.4
Dive, C.5
-
76
-
-
0030810926
-
X-linked IAP is a direct inhibitor of cell-death proteases
-
Deveraux Q. L., Takahashi R., Salvesen G. S., Reed J. C. X-linked IAP is a direct inhibitor of cell-death proteases. Nature. 388:1997;300-304.
-
(1997)
Nature
, vol.388
, pp. 300-304
-
-
Deveraux, Q.L.1
Takahashi, R.2
Salvesen, G.S.3
Reed, J.C.4
-
77
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone M. H., Roy N., Stennicke H. R., Salvesen G. S., Franke T. F., Stanbridge E., Frisch S., Reed J. C. Regulation of cell death protease caspase-9 by phosphorylation. Science. 282:1998;1318-1321.
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
Frisch, S.7
Reed, J.C.8
-
78
-
-
0030746636
-
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
-
Ambrosini G., Adida C., Altieri D. C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat. Med. 3:1997;917-921.
-
(1997)
Nat. Med.
, vol.3
, pp. 917-921
-
-
Ambrosini, G.1
Adida, C.2
Altieri, D.C.3
-
79
-
-
0032403126
-
IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs
-
Tamm I., Wang Y., Sausville E., Scudiero D. A., Vigna N., Oltersdorf T., Reed J. C. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 58:1998;5315-5320.
-
(1998)
Cancer Res.
, vol.58
, pp. 5315-5320
-
-
Tamm, I.1
Wang, Y.2
Sausville, E.3
Scudiero, D.A.4
Vigna, N.5
Oltersdorf, T.6
Reed, J.C.7
-
80
-
-
0032533494
-
Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer
-
Kawasaki H., Altieri D. C., Lu C. D., Toyoda M., Tenjo T., Tanigawa N. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res. 58:1998;5071-5074.
-
(1998)
Cancer Res.
, vol.58
, pp. 5071-5074
-
-
Kawasaki, H.1
Altieri, D.C.2
Lu, C.D.3
Toyoda, M.4
Tenjo, T.5
Tanigawa, N.6
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