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Volumn 72, Issue 2, 1999, Pages 529-540

Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis

Author keywords

Bcl 2; Caspase; Membrane depolarization; Reactive oxygen species; Staurosporine

Indexed keywords

4 HYDROXYNONENAL; CALCIUM; CASPASE; CYCLOSPORIN A; DIMETHYL SULFOXIDE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RUTHENIUM RED; STAUROSPORINE;

EID: 0032902145     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0720529.x     Document Type: Article
Times cited : (300)

References (86)
  • 1
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona M., Dypbukt J. M., Bonfoco E., Zhivotovsky B., Orrenius S., Lipton S. A., and Nicotera P. (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15, 961-973.
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 5
    • 0031004788 scopus 로고    scopus 로고
    • Amyloid β-peptide disrupts barrier and transport functions and induces apoptosis in vascular endothelial cells
    • Blanc E. M., Toborek M.,. Mark R. J., Hennig B., and Mattson M. P. (1997) Amyloid β-peptide disrupts barrier and transport functions and induces apoptosis in vascular endothelial cells. J. Neurochem. 68, 1870-1881.
    • (1997) J. Neurochem. , vol.68 , pp. 1870-1881
    • Blanc, E.M.1    Toborek, M.2    Mark, R.J.3    Hennig, B.4    Mattson, M.P.5
  • 6
    • 0029614765 scopus 로고
    • Neural apoptosis
    • Bredesen D. E. (1995) Neural apoptosis. Ann. Neurol. 38, 839-851.
    • (1995) Ann. Neurol. , vol.38 , pp. 839-851
    • Bredesen, D.E.1
  • 7
    • 0031962324 scopus 로고    scopus 로고
    • Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid β-peptide
    • Bruce-Keller A. J., Begley J. G., Fu W., Butterfield, D. A., Bredesen D. E., Hutchins J. B., Hensley K., and Mattson M. P. (1997) Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid β-peptide. J. Neurochem. 70, 31-39.
    • (1997) J. Neurochem. , vol.70 , pp. 31-39
    • Bruce-Keller, A.J.1    Begley, J.G.2    Fu, W.3    Butterfield, D.A.4    Bredesen, D.E.5    Hutchins, J.B.6    Hensley, K.7    Mattson, M.P.8
  • 9
    • 0030273118 scopus 로고    scopus 로고
    • Ischemia-induced neuronal apoptosis
    • Choi D. W. (1996) Ischemia-induced neuronal apoptosis. Curr. Opin. Neurobiol. 6, 667-672.
    • (1996) Curr. Opin. Neurobiol. , vol.6 , pp. 667-672
    • Choi, D.W.1
  • 10
    • 0030876498 scopus 로고    scopus 로고
    • The importance of oxidative stress in apoptosis
    • Clutton S. (1997) The importance of oxidative stress in apoptosis. Br. Med. Bull. 53, 662-668.
    • (1997) Br. Med. Bull. , vol.53 , pp. 662-668
    • Clutton, S.1
  • 11
    • 0030915587 scopus 로고    scopus 로고
    • Intracellular ATP levels determine cell death fate by apoptosis or necrosis
    • Eguchi Y., Shimizu S., and Tsujimoto Y. (1997) Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res. 57, 1835-1840.
    • (1997) Cancer Res. , vol.57 , pp. 1835-1840
    • Eguchi, Y.1    Shimizu, S.2    Tsujimoto, Y.3
  • 12
    • 0022492812 scopus 로고
    • Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: Spectral and metabolic properties
    • Emans R. K., Grunwald R., and Lemasters J. J. (1986) Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochim. Biophys. Acta 850, 436-448.
    • (1986) Biochim. Biophys. Acta , vol.850 , pp. 436-448
    • Emans, R.K.1    Grunwald, R.2    Lemasters, J.J.3
  • 13
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
    • Esterbauer H., Schaur R. J., and Zollner H. (1991) Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. 11, 81-128.
    • (1991) Free Radic. Biol. Med. , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 14
    • 0031773366 scopus 로고    scopus 로고
    • Catecholamines potentiate amyloid β-peptide neurotoxicity: Involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis
    • Fu W., Luo H., Parthasarathy S., and Mattson M. P. (1998) Catecholamines potentiate amyloid β-peptide neurotoxicity: involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis. Neurobiol. Dis. 5, 229-243.
    • (1998) Neurobiol. Dis. , vol.5 , pp. 229-243
    • Fu, W.1    Luo, H.2    Parthasarathy, S.3    Mattson, M.P.4
  • 15
    • 0025292743 scopus 로고
    • Mechanisms by which mitochondria transport calcium
    • Gunter T. E. and Pfeiffer D. R. (1990) Mechanisms by which mitochondria transport calcium. Am. J. Physiol. 258, C755-C786.
    • (1990) Am. J. Physiol. , vol.258
    • Gunter, T.E.1    Pfeiffer, D.R.2
  • 16
    • 0030917601 scopus 로고    scopus 로고
    • Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid β-peptide: Involvement of calcium and oxyradicals
    • Guo Q., Sopher B., Furukawa K., Pham D., Robinson N., Martin G., and Mattson M. P. (1997) Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid β-peptide: involvement of calcium and oxyradicals. J. Neurosci. 17, 4212-4222.
    • (1997) J. Neurosci. , vol.17 , pp. 4212-4222
    • Guo, Q.1    Sopher, B.2    Furukawa, K.3    Pham, D.4    Robinson, N.5    Martin, G.6    Mattson, M.P.7
  • 17
    • 0032539814 scopus 로고    scopus 로고
    • Calbindin D28k blocks the pro-apoptotic actions of mutant presenilin-1: Reduced oxidative stress and preserved mitochondrial function
    • Guo Q., Christakos S., Robinson N., and Mattson M. P. (1998) Calbindin D28k blocks the pro-apoptotic actions of mutant presenilin-1: reduced oxidative stress and preserved mitochondrial function. Proc. Natl. Acad. Sci. USA 95, 3227-3232.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3227-3232
    • Guo, Q.1    Christakos, S.2    Robinson, N.3    Mattson, M.P.4
  • 18
    • 0031571676 scopus 로고    scopus 로고
    • Fluorometric and colorimetric detection of caspase activity associated with apoptosis
    • Gurtu V., Kain S. R., and Zhang G. (1997) Fluorometric and colorimetric detection of caspase activity associated with apoptosis. Anal. Biochem. 251, 98-102.
    • (1997) Anal. Biochem. , vol.251 , pp. 98-102
    • Gurtu, V.1    Kain, S.R.2    Zhang, G.3
  • 21
    • 0030824575 scopus 로고    scopus 로고
    • Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2
    • He H., Lam M., McCormick T. S., and Distelhorst C. W. (1997) Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2. J. Cell Biol. 138, 1219-1228.
    • (1997) J. Cell Biol. , vol.138 , pp. 1219-1228
    • He, H.1    Lam, M.2    McCormick, T.S.3    Distelhorst, C.W.4
  • 22
    • 0032536519 scopus 로고    scopus 로고
    • Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis
    • Hirata H., Takahashi A., Kobayashi S., Yonehara S., Sawai H., Okazaki T., Yamamoto K., and Sasada M. (1998) Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis. J. Exp. Med. 187, 587-600.
    • (1998) J. Exp. Med. , vol.187 , pp. 587-600
    • Hirata, H.1    Takahashi, A.2    Kobayashi, S.3    Yonehara, S.4    Sawai, H.5    Okazaki, T.6    Yamamoto, K.7    Sasada, M.8
  • 23
  • 25
    • 0030982181 scopus 로고    scopus 로고
    • Mitochondrial regulation of store operated calcium signaling in T lymphocytes
    • Hoth M., Fanger C. M., and Lewis R. S. (1997) Mitochondrial regulation of store operated calcium signaling in T lymphocytes. J. Cell Biol. 137, 633-648.
    • (1997) J. Cell Biol. , vol.137 , pp. 633-648
    • Hoth, M.1    Fanger, C.M.2    Lewis, R.S.3
  • 26
    • 0029944142 scopus 로고    scopus 로고
    • Role of Ced-3/ICE-family proteases in staurosporine induced programmed cell death
    • Jacobson M. D., Weil M., and Raff M. C. (1996) Role of Ced-3/ICE-family proteases in staurosporine induced programmed cell death. J. Cell Biol. 133, 1041-1051.
    • (1996) J. Cell Biol. , vol.133 , pp. 1041-1051
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 27
    • 0019480519 scopus 로고
    • Monitoring relative mitochondrial transmembrane potential in living cells by fluorescence microscopy
    • Johnson L. V., Walsh M. L., Bokus B. J., and Chen L. B. (1981) Monitoring relative mitochondrial transmembrane potential in living cells by fluorescence microscopy. J. Cell Biol. 88, 526-532.
    • (1981) J. Cell Biol. , vol.88 , pp. 526-532
    • Johnson, L.V.1    Walsh, M.L.2    Bokus, B.J.3    Chen, L.B.4
  • 29
    • 0345055313 scopus 로고    scopus 로고
    • Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production
    • Keller J. N., Guo Q., Holtsberg F. W., Bruce-Keller A. J., and Mattson M. P. (1998a) Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production. J. Neurosci. 18, 4439-4450.
    • (1998) J. Neurosci. , vol.18 , pp. 4439-4450
    • Keller, J.N.1    Guo, Q.2    Holtsberg, F.W.3    Bruce-Keller, A.J.4    Mattson, M.P.5
  • 30
    • 17344371804 scopus 로고    scopus 로고
    • Mitochondrial MnSOD prevents neural apoptosis and reduces ischemic brain injury: Suppression of peroxynitrite production, lipid peroxidation and mitochondrial dysfunction
    • Keller J. N., Kindey M. S., Holtsberg F. W., St. Clair D. K., Yen H. C., Germeyer A., Steiner S. M., Bruce-Keller A. J., Hutchins J. B., and Mattson M. P. (1998b) Mitochondrial MnSOD prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation and mitochondrial dysfunction. J. Neurosci. 18, 687-697.
    • (1998) J. Neurosci. , vol.18 , pp. 687-697
    • Keller, J.N.1    Kindey, M.S.2    Holtsberg, F.W.3    St Clair, D.K.4    Yen, H.C.5    Germeyer, A.6    Steiner, S.M.7    Bruce-Keller, A.J.8    Hutchins, J.B.9    Mattson, M.P.10
  • 31
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck R. M., Bossy-Wetzel E., Green D. R., and Newmeyer D. D. (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275, 1132-1136.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 34
    • 0027362667 scopus 로고
    • Investigation of the subcellular distribution of the bcl-2 oncoprotein: Residence in the nuclear envelope, endoplasmic recitulum, and outer mitochondrial membrane
    • Krafewski S., Tanaka S., Takayama S., Schibler M. J., Fenton W., and Reed J. C. (1993) Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic recitulum, and outer mitochondrial membrane. Cancer Res. 53, 4701-4714.
    • (1993) Cancer Res. , vol.53 , pp. 4701-4714
    • Krafewski, S.1    Tanaka, S.2    Takayama, S.3    Schibler, M.J.4    Fenton, W.5    Reed, J.C.6
  • 35
    • 0029866196 scopus 로고    scopus 로고
    • 4-hydroxyhexenal is a potent inducer of the mitochondrial permeability transition
    • Kristal B. S., Park B. K., and Yu B. P. (1996) 4-Hydroxyhexenal is a potent inducer of the mitochondrial permeability transition. J. Biol. Chem. 271, 6033-6038.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6033-6038
    • Kristal, B.S.1    Park, B.K.2    Yu, B.P.3
  • 37
    • 0030986669 scopus 로고    scopus 로고
    • Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis
    • Kruman I., Bruce-Keller A. J., Bredesen D. E., Waeg G., and Mattson M. P. (1997) Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J. Neurosci. 17, 5089-5100.
    • (1997) J. Neurosci. , vol.17 , pp. 5089-5100
    • Kruman, I.1    Bruce-Keller, A.J.2    Bredesen, D.E.3    Waeg, G.4    Mattson, M.P.5
  • 38
    • 0032006868 scopus 로고    scopus 로고
    • Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells
    • Kruman I., Guo Q., and Mattson M. P. (1998) Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells. J. Neurosci. Res. 51, 293-308.
    • (1998) J. Neurosci. Res. , vol.51 , pp. 293-308
    • Kruman, I.1    Guo, Q.2    Mattson, M.P.3
  • 40
    • 17544372082 scopus 로고    scopus 로고
    • A role for calcium influx in the regulation of mitochondrial calcium in endothelial cells
    • Lawrie A. M., Rizzuto R., Pozzan T., and Simpson A. W. (1996) A role for calcium influx in the regulation of mitochondrial calcium in endothelial cells. J. Biol. Chem. 271, 10753-10759.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10753-10759
    • Lawrie, A.M.1    Rizzuto, R.2    Pozzan, T.3    Simpson, A.W.4
  • 41
    • 0030900980 scopus 로고    scopus 로고
    • Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
    • Leist M., Single B., Castoldi A. F., Kuhnle S., and Nicotera P. (1997) Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J. Exp. Med. 185, 1481-1486.
    • (1997) J. Exp. Med. , vol.185 , pp. 1481-1486
    • Leist, M.1    Single, B.2    Castoldi, A.F.3    Kuhnle, S.4    Nicotera, P.5
  • 42
    • 0343307138 scopus 로고    scopus 로고
    • Death by design. Programmed cell death in cardiovascular biology and disease
    • MacLellan W. R. and Schneider M. D. (1997) Death by design. Programmed cell death in cardiovascular biology and disease. Circ. Res. 81, 137-144.
    • (1997) Circ. Res. , vol.81 , pp. 137-144
    • Maclellan, W.R.1    Schneider, M.D.2
  • 43
    • 0030897988 scopus 로고    scopus 로고
    • Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases
    • Margolin N., Raybuck S. A., Wilson K. P., Chen W., Fox T., Gu Y., and Livingston D. J. (1997) Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases. J. Biol. Chem. 272, 7223-7228.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7223-7228
    • Margolin, N.1    Raybuck, S.A.2    Wilson, K.P.3    Chen, W.4    Fox, T.5    Gu, Y.6    Livingston, D.J.7
  • 46
    • 0031020993 scopus 로고    scopus 로고
    • Amyloid β-peptide impairs glucose transport in hippocampal and cortical neurons: Involvement of membrane lipid peroxidation
    • Mark R. J., Pang Z., Geddes J. W., Uchida K., and Mattson M. P. (1997a) Amyloid β-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation. J. Neurosci. 17, 1046-1054.
    • (1997) J. Neurosci. , vol.17 , pp. 1046-1054
    • Mark, R.J.1    Pang, Z.2    Geddes, J.W.3    Uchida, K.4    Mattson, M.P.5
  • 47
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal in disruption of ion homeostasis and neuronal death induced by amyloid β-peptide
    • Mark R. J., Lovell M. A., Markesbery W. R., Uchida K., and Mattson M. P. (1997b) A role for 4-hydroxynonenal in disruption of ion homeostasis and neuronal death induced by amyloid β-peptide. J. Neurochem. 68, 255-264.
    • (1997) J. Neurochem. , vol.68 , pp. 255-264
    • Mark, R.J.1    Lovell, M.A.2    Markesbery, W.R.3    Uchida, K.4    Mattson, M.P.5
  • 48
    • 0031465119 scopus 로고    scopus 로고
    • Apoptotic cell death induced by inhibitors of energy conservation - Bcl-2 inhibits apoptosis downstream of a fall of ATP level
    • Marton A., Mihalik R., Bratincsak A., Adleff V., Petak I., Vegh M., Bauer P. I., and Krajcsi P. (1997) Apoptotic cell death induced by inhibitors of energy conservation - Bcl-2 inhibits apoptosis downstream of a fall of ATP level. Eur. J. Biochem. 250, 467-475.
    • (1997) Eur. J. Biochem. , vol.250 , pp. 467-475
    • Marton, A.1    Mihalik, R.2    Bratincsak, A.3    Adleff, V.4    Petak, I.5    Vegh, M.6    Bauer, P.I.7    Krajcsi, P.8
  • 49
    • 0031606827 scopus 로고    scopus 로고
    • Free radicals, calcium, and the synaptic plasticity-cell death continuum: Emerging roles of the transcription factor NF-κB
    • Mattson M. P. (1998) Free radicals, calcium, and the synaptic plasticity-cell death continuum: emerging roles of the transcription factor NF-κB. Int. Rev. Neurobiol. 42, 103-168.
    • (1998) Int. Rev. Neurobiol. , vol.42 , pp. 103-168
    • Mattson, M.P.1
  • 50
    • 0024543729 scopus 로고
    • Roles for mitotic history in the generation and degeneration of neuroarchitecture
    • Mattson M. P., Guthrie P. B., Hayes B. C., and Kater S. B. (1989) Roles for mitotic history in the generation and degeneration of neuroarchitecture. J. Neurosci. 9, 1223-1230.
    • (1989) J. Neurosci. , vol.9 , pp. 1223-1230
    • Mattson, M.P.1    Guthrie, P.B.2    Hayes, B.C.3    Kater, S.B.4
  • 51
    • 0026570528 scopus 로고
    • β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • Mattson M. P., Cheng B., Davis D., Bryant K., Lieberburg E., and Rydel R. E. (1992) β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci. 12, 376-389.
    • (1992) J. Neurosci. , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Lieberburg, E.5    Rydel, R.E.6
  • 52
    • 0027319561 scopus 로고
    • Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose
    • Mattson M. P., Zhang Y., and Bose S. (1993) Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose. Exp. Neurol. 121, 1-13.
    • (1993) Exp. Neurol. , vol.121 , pp. 1-13
    • Mattson, M.P.1    Zhang, Y.2    Bose, S.3
  • 53
    • 0030611750 scopus 로고    scopus 로고
    • Activation of NF-κB protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of Mn-SOD and suppression of peroxynitrite production and protein tyrosine nitration
    • Mattson M. P., Goodman Y., Luo H., Fu W., and Furukawa K. (1997) Activation of NF-κB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of Mn-SOD and suppression of peroxynitrite production and protein tyrosine nitration. J. Neurosci. Res. 49, 681-697.
    • (1997) J. Neurosci. Res. , vol.49 , pp. 681-697
    • Mattson, M.P.1    Goodman, Y.2    Luo, H.3    Fu, W.4    Furukawa, K.5
  • 54
    • 0031982670 scopus 로고    scopus 로고
    • Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease
    • Mattson M. P., Guo Q., Furukawa K., and Pedersen W. A. (1998a) Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease. J. Neurochem. 70, 1-14.
    • (1998) J. Neurochem. , vol.70 , pp. 1-14
    • Mattson, M.P.1    Guo, Q.2    Furukawa, K.3    Pedersen, W.A.4
  • 56
    • 0031581060 scopus 로고    scopus 로고
    • The role of calcium in the regulation of apoptosis
    • McConkey D. J. and Orrenius S. (1997) The role of calcium in the regulation of apoptosis. Biochem. Biophys. Res. Commun. 239, 357-366.
    • (1997) Biochem. Biophys. Res. Commun. , vol.239 , pp. 357-366
    • McConkey, D.J.1    Orrenius, S.2
  • 57
    • 0031080248 scopus 로고    scopus 로고
    • The role of the caspase family of cysteine proteases in apoptosis
    • Miller D. K. (1997) The role of the caspase family of cysteine proteases in apoptosis. Semin. Immunol. 9, 35-49.
    • (1997) Semin. Immunol. , vol.9 , pp. 35-49
    • Miller, D.K.1
  • 62
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim R. W. (1991) Cell death during development of the nervous system. Annu. Rev. Neurosci. 14, 453-501.
    • (1991) Annu. Rev. Neurosci. , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 63
    • 0030946503 scopus 로고    scopus 로고
    • Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: Acute excitotoxic necrosis and delayed apoptosis
    • Pang Z. and Geddes J. W. (1997) Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis. J. Neurosci. 17, 3064-3073.
    • (1997) J. Neurosci. , vol.17 , pp. 3064-3073
    • Pang, Z.1    Geddes, J.W.2
  • 64
    • 0029982148 scopus 로고    scopus 로고
    • The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition
    • Pastorino J. G., Simbula G., Yamamoto K., Glascott P. A., Rothman R. J., and Farber J. (1996) The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition. J. Biol. Chem. 271, 29792-29798.
    • (1996) J. Biol. Chem. , vol.271 , pp. 29792-29798
    • Pastorino, J.G.1    Simbula, G.2    Yamamoto, K.3    Glascott, P.A.4    Rothman, R.J.5    Farber, J.6
  • 65
    • 0028074839 scopus 로고
    • Regulation of the permeability transition pore, a voltage-dependent mitochondrial calcium channel inhibited by cyclosporin A
    • Petronilli V., Nicolli A., Costantini P., Colonna R., and Bernardi P. (1994) Regulation of the permeability transition pore, a voltage-dependent mitochondrial calcium channel inhibited by cyclosporin A. Biochim. Biophys. Acta 1187, 255-259.
    • (1994) Biochim. Biophys. Acta , vol.1187 , pp. 255-259
    • Petronilli, V.1    Nicolli, A.2    Costantini, P.3    Colonna, R.4    Bernardi, P.5
  • 67
    • 0024394417 scopus 로고
    • Staurosporine, K-252 and UN01; potent but nonspecific inhibitors of protein kinases
    • Reugg U. T. and Burgess G. M. (1989) Staurosporine, K-252 and UN01; potent but nonspecific inhibitors of protein kinases. Trends Pharmacol. Sci. 10, 218-220.
    • (1989) Trends Pharmacol. Sci. , vol.10 , pp. 218-220
    • Reugg, U.T.1    Burgess, G.M.2
  • 68
    • 0027325097 scopus 로고
    • Pro-oxidants and mitochondrial calcium: Their relationship to apoptosis and oncogenesis
    • Richter C. (1993) Pro-oxidants and mitochondrial calcium: their relationship to apoptosis and oncogenesis. FEBS Lett. 325, 104-107.
    • (1993) FEBS Lett. , vol.325 , pp. 104-107
    • Richter, C.1
  • 69
    • 0025960006 scopus 로고
    • 2+ homeostasis, cell death, proliferation, and differentiation
    • 2+ homeostasis, cell death, proliferation, and differentiation. Chem. Biol. Interact. 77, 1-23.
    • (1991) Chem. Biol. Interact. , vol.77 , pp. 1-23
    • Richter, C.1    Kass, G.E.N.2
  • 70
    • 0027410845 scopus 로고
    • Mitochondrial calcium release induced by prooxidants
    • Richter C. and Schlegel J. (1993) Mitochondrial calcium release induced by prooxidants. Toxicol. Lett. 67, 119-127.
    • (1993) Toxicol. Lett. , vol.67 , pp. 119-127
    • Richter, C.1    Schlegel, J.2
  • 71
    • 0030779146 scopus 로고    scopus 로고
    • Recognition and phagocytosis of cells undergoing apoptosis
    • Savill J. (1997) Recognition and phagocytosis of cells undergoing apoptosis. Br. Med. Bull. 53, 491-508.
    • (1997) Br. Med. Bull. , vol.53 , pp. 491-508
    • Savill, J.1
  • 73
    • 0029991245 scopus 로고    scopus 로고
    • Neurobiology of Huntington's disease
    • Sharp A. H. and Ross C. A. (1996) Neurobiology of Huntington's disease. Neurobiol. Dis. 3, 3-15.
    • (1996) Neurobiol. Dis. , vol.3 , pp. 3-15
    • Sharp, A.H.1    Ross, C.A.2
  • 74
    • 0029891535 scopus 로고    scopus 로고
    • Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: Possible involvement of common mediators in apoptotic and necrotic signal transductions
    • Shimizu S., Eguchi Y., Kamiike W., Waguri S., Uchiyama Y., Matsuda H., and Tsujimoto Y. (1996) Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions. Oncogene 12, 2045-2050.
    • (1996) Oncogene , vol.12 , pp. 2045-2050
    • Shimizu, S.1    Eguchi, Y.2    Kamiike, W.3    Waguri, S.4    Uchiyama, Y.5    Matsuda, H.6    Tsujimoto, Y.7
  • 76
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H. (1995) Mechanisms and genes of cellular suicide. Science 267, 1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 77
    • 0029590050 scopus 로고
    • Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat
    • Uchino H., Elmer E., Uchino K., Lindvall O., and Siesjo B. K. (1995) Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat. Acta Physiol. Scand. 155, 469-471.
    • (1995) Acta Physiol. Scand. , vol.155 , pp. 469-471
    • Uchino, H.1    Elmer, E.2    Uchino, K.3    Lindvall, O.4    Siesjo, B.K.5
  • 78
    • 0028046038 scopus 로고
    • Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40
    • Vayssiere J. L., Petit P. X., Risler Y., and Mignotte B. (1994) Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc. Natl. Acad. Sci. USA 91, 11752-11756.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11752-11756
    • Vayssiere, J.L.1    Petit, P.X.2    Risler, Y.3    Mignotte, B.4
  • 79
    • 0030587437 scopus 로고    scopus 로고
    • Cyclosporin A rescues thymocytes from apoptosis induced by very low concentrations of thapsigargin: Effects on mitochondrial function
    • Waring P. and Beaver J. (1996) Cyclosporin A rescues thymocytes from apoptosis induced by very low concentrations of thapsigargin: effects on mitochondrial function. Exp. Cell Res. 227, 264-276.
    • (1996) Exp. Cell Res. , vol.227 , pp. 264-276
    • Waring, P.1    Beaver, J.2
  • 80
    • 0030894671 scopus 로고    scopus 로고
    • Thiourea and dimethylthiourea inhibit peroxynitrite-dependent damage: Nonspecificity as hydroxyl radical scavengers
    • Whiteman M. and Halliwell B. (1997) Thiourea and dimethylthiourea inhibit peroxynitrite-dependent damage: nonspecificity as hydroxyl radical scavengers. Free Radic. Biol. Med 22, 1309-1312.
    • (1997) Free Radic. Biol. Med , vol.22 , pp. 1309-1312
    • Whiteman, M.1    Halliwell, B.2
  • 81
  • 82
  • 84
    • 0030987071 scopus 로고    scopus 로고
    • Transducing signals of life and death
    • Yuan J. (1997) Transducing signals of life and death. Curr. Opin. Cell Biol. 9, 247-251.
    • (1997) Curr. Opin. Cell Biol. , vol.9 , pp. 247-251
    • Yuan, J.1
  • 85
  • 86
    • 0029983059 scopus 로고    scopus 로고
    • Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis
    • Zamzami N., Marchetti P., Castedo M., Hirsch T., Susin S. A., Masse B., and Kroemer G. (1996) Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis. FEBS Lett. 384, 53-57.
    • (1996) FEBS Lett. , vol.384 , pp. 53-57
    • Zamzami, N.1    Marchetti, P.2    Castedo, M.3    Hirsch, T.4    Susin, S.A.5    Masse, B.6    Kroemer, G.7


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