-
1
-
-
0026721068
-
A family of human cdc2-related protein kinases
-
Meyerson, M., Enders, G. H., Wu, C. L., Su, L. K., Gorka, C., Nelson, C., Harlow, E., and Tsai, L. H. A family of human cdc2-related protein kinases. EMBO J., 11: 2909-2917, 1992.
-
(1992)
EMBO J.
, vol.11
, pp. 2909-2917
-
-
Meyerson, M.1
Enders, G.H.2
Wu, C.L.3
Su, L.K.4
Gorka, C.5
Nelson, C.6
Harlow, E.7
Tsai, L.H.8
-
2
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
Sherr, C. J., and Roberts, J. M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev., 9: 1149-1163, 1995.
-
(1995)
Genes Dev.
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
4
-
-
0028961521
-
INK4 expression in primary lung cancers and cell lines
-
INK4 expression in primary lung cancers and cell lines. Cancer Res., 55: 505-509, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 505-509
-
-
Shapiro, G.I.1
Edwards, C.D.2
Kobzik, L.3
Godleski, J.4
Richards, W.5
Sugarbaker, D.J.6
Rollins, B.J.7
-
5
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., and Vogelstein, B. WAF1, a potential mediator of p53 tumor suppression. Cell, 75: 817-825, 1993.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
6
-
-
0028963841
-
P53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
-
Macleod, K. F., Sherry, N., Hannon, G., Beach, D., Tokino, T., Kinzler, K., Vogelstein, B., and Jacks, T. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev., 9: 935-944, 1995.
-
(1995)
Genes Dev.
, vol.9
, pp. 935-944
-
-
Macleod, K.F.1
Sherry, N.2
Hannon, G.3
Beach, D.4
Tokino, T.5
Kinzler, K.6
Vogelstein, B.7
Jacks, T.8
-
7
-
-
0028236846
-
Induction of Waf1/CIP1 by a p53-independent pathway
-
Michieli, P., Chedid, M., Lin, D., Pierce, J. H., Mercer, E., and Givol, D. Induction of Waf1/CIP1 by a p53-independent pathway. Cancer Res., 54: 3391-3395, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3391-3395
-
-
Michieli, P.1
Chedid, M.2
Lin, D.3
Pierce, J.H.4
Mercer, E.5
Givol, D.6
-
9
-
-
0029024015
-
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
-
Pagano, M., Tam, S. W., Thodoras, A. M., Beer-Romero, P., Del Sal, G., Chau, V., Yew, P. R., Draetta, G. F., and Rolfe, M. Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science (Washington DC), 269: 682-685, 1995.
-
(1995)
Science (Washington DC)
, vol.269
, pp. 682-685
-
-
Pagano, M.1
Tam, S.W.2
Thodoras, A.M.3
Beer-Romero, P.4
Del Sal, G.5
Chau, V.6
Yew, P.R.7
Draetta, G.F.8
Rolfe, M.9
-
10
-
-
0031048716
-
Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
-
Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nat. Med., 3: 222-225, 1997.
-
(1997)
Nat. Med.
, vol.3
, pp. 222-225
-
-
Porter, P.L.1
Malone, K.E.2
Heagerty, P.J.3
Alexander, G.M.4
Gatti, L.A.5
Firpo, E.J.6
Daling, J.R.7
Roberts, J.M.8
-
11
-
-
16944363001
-
Kip1 protein: Prognostic implications in primary breast cancer
-
Kip1 protein: prognostic implications in primary breast cancer. Nat. Med., 3: 227-230, 1997.
-
(1997)
Nat. Med.
, vol.3
, pp. 227-230
-
-
Catzavelos, C.1
Bhattacharya, N.2
Ung, Y.C.3
Wilson, J.A.4
Roncari, L.5
Sandhu, C.6
Shaw, P.7
Yeger, H.8
Morava-Protzer, I.9
Kapusta, L.10
Franssen, E.11
Pritchard, K.I.12
Slingerland, J.M.13
-
12
-
-
0031048236
-
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
-
Loda, M., Cukor, B., Tam, S. W., Lavin, P., Fiorentino, M., Draetta, G. F., Jessup, J. M., and Pagano, M. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat. Med., 3: 231-234, 1997.
-
(1997)
Nat. Med.
, vol.3
, pp. 231-234
-
-
Loda, M.1
Cukor, B.2
Tam, S.W.3
Lavin, P.4
Fiorentino, M.5
Draetta, G.F.6
Jessup, J.M.7
Pagano, M.8
-
13
-
-
14444268041
-
Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer
-
Esposito, V., Baldi, A., De Luca, A., Groger, A. M., Loda, M., Giordano, G. G., Caputi, M., Baldi, F., Pagano, M., and Giordano, A. Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer. Cancer Res., 57: 3381-3385, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 3381-3385
-
-
Esposito, V.1
Baldi, A.2
De Luca, A.3
Groger, A.M.4
Loda, M.5
Giordano, G.G.6
Caputi, M.7
Baldi, F.8
Pagano, M.9
Giordano, A.10
-
14
-
-
0031961995
-
Cip1/Waf1 at both the G1/S and G2/M cell cycle transitions: PRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
-
Cip1/Waf1 at both the G1/S and G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol. Cell. Biol., 18: 629-643, 1998.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 629-643
-
-
Niculescu, A.B.1
Chen, X.2
Smeets, M.3
Hengst, L.4
Prives, C.5
Reed, S.I.6
-
17
-
-
0029054399
-
Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16
-
Lukas, J., Parry, D., Aagaard, L., Mann, D. J., Bartkova, J., Strauss, M., Peters, G., and Bartek, J. Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16. Nature (Lond.), 375: 503-506, 1995.
-
(1995)
Nature (Lond.)
, vol.375
, pp. 503-506
-
-
Lukas, J.1
Parry, D.2
Aagaard, L.3
Mann, D.J.4
Bartkova, J.5
Strauss, M.6
Peters, G.7
Bartek, J.8
-
18
-
-
0029811984
-
Genetic determinants of p53-induced apoptosis and growth arrest
-
Polyak, K., Waldman, T., He, T. C., Kinzler, K. W., and Vogelstein, B. Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev., 1996: 1945-1952, 1996.
-
(1996)
Genes Dev.
, vol.1996
, pp. 1945-1952
-
-
Polyak, K.1
Waldman, T.2
He, T.C.3
Kinzler, K.W.4
Vogelstein, B.5
-
19
-
-
0030842655
-
Cell-cycle arrest versus cell death in cancer therapy
-
Waldman, T., Zhang, Y., Dillehay, L., Yu, J., Kinzler, K., Vogelstein, B., and Williams, J. Cell-cycle arrest versus cell death in cancer therapy. Nat. Med., 3: 1034-1036, 1997.
-
(1997)
Nat. Med.
, vol.3
, pp. 1034-1036
-
-
Waldman, T.1
Zhang, Y.2
Dillehay, L.3
Yu, J.4
Kinzler, K.5
Vogelstein, B.6
Williams, J.7
-
20
-
-
0029982829
-
Reversible, p16-mediated cell cycle arrest as protection from chemotherapy
-
Stone, S., Dayananth, P., and Kamb, A. Reversible, p16-mediated cell cycle arrest as protection from chemotherapy. Cancer Res., 56: 3199-3202, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 3199-3202
-
-
Stone, S.1
Dayananth, P.2
Kamb, A.3
-
21
-
-
0031439355
-
Promoting apoptosis: A novel activity associated with the cyclin-dependent kinase inhibitor p27
-
Katayose, Y., Kim, M., Rakkar, A. N. S., Li, Z., Cowan, K. H., and Seth, P. Promoting apoptosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27. Cancer Res., 57: 5441-5445, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 5441-5445
-
-
Katayose, Y.1
Kim, M.2
Rakkar, A.N.S.3
Li, Z.4
Cowan, K.H.5
Seth, P.6
-
23
-
-
0033522231
-
Kip1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity
-
Kip1 in inducing cell cycle arrest, apoptosis and inhibition of tumorigenicity. Oncogene, 18: 1663-1676, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 1663-1676
-
-
Schreiber, M.1
Muller, W.J.2
Singh, G.3
Graham, F.L.4
-
24
-
-
0030271304
-
Chemical inhibitors of cyclin-dependent kinases
-
Meijer, L. Chemical inhibitors of cyclin-dependent kinases. Trends Cell Biol., 6: 393-397, 1996.
-
(1996)
Trends Cell Biol.
, vol.6
, pp. 393-397
-
-
Meijer, L.1
-
25
-
-
0029913242
-
Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons
-
Park, D. S., Farinelli, S. E., and Greene, L. A. Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons. J. Biol. Chem., 271: 8161-8169, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 8161-8169
-
-
Park, D.S.1
Farinelli, S.E.2
Greene, L.A.3
-
26
-
-
0029826236
-
P53-independent induction of apoptosis by cyclin-dependent kinase inhibition
-
Shibata, Y., Nishimura, S., Okuyama, A., and Nakamura, T. p53-independent induction of apoptosis by cyclin-dependent kinase inhibition. Cell Growth Differ., 7: 887-891, 1996.
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 887-891
-
-
Shibata, Y.1
Nishimura, S.2
Okuyama, A.3
Nakamura, T.4
-
27
-
-
0029807115
-
Flavopiridol (L86 8275; NSC 649890), a new kinase inhibitor for tumor therapy
-
Sedlacek, H. H., Czech, J., Naik, R., Kaur, G., Worland, P., Losiewicz, M., Parker, B., Carlson, B., Smith, A., Senderowicz, A., and Sausville, E. A. Flavopiridol (L86 8275; NSC 649890), a new kinase inhibitor for tumor therapy. Int. J. Oncol., 9: 1143-1168, 1996.
-
(1996)
Int. J. Oncol.
, vol.9
, pp. 1143-1168
-
-
Sedlacek, H.H.1
Czech, J.2
Naik, R.3
Kaur, G.4
Worland, P.5
Losiewicz, M.6
Parker, B.7
Carlson, B.8
Smith, A.9
Senderowicz, A.10
Sausville, E.A.11
-
28
-
-
0029665778
-
Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK)2 and CDK4 in human breast carcinoma cells
-
Carlson, B. A., Dubay, M. M., Sausville, E. A., Brizuela, L., and Worland, P. J. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK)2 and CDK4 in human breast carcinoma cells. Cancer Res., 56: 2973-2978, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 2973-2978
-
-
Carlson, B.A.1
Dubay, M.M.2
Sausville, E.A.3
Brizuela, L.4
Worland, P.J.5
-
29
-
-
0000602266
-
Inhibition of CDK2, CDK4 and CDK7 by flavopiridol and structural analogs
-
Carlson, B. A., Pearlstein, R. A., Naik, R. G., Sedlacedk, H. H., Sausville, E. A., and Worland, P. J. Inhibition of CDK2, CDK4 and CDK7 by flavopiridol and structural analogs. Proc. Am. Assoc. Cancer Res., 37: A2897, 1996.
-
(1996)
Proc. Am. Assoc. Cancer Res.
, vol.37
-
-
Carlson, B.A.1
Pearlstein, R.A.2
Naik, R.G.3
Sedlacedk, H.H.4
Sausville, E.A.5
Worland, P.J.6
-
30
-
-
0029993339
-
Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase
-
De Azevedo, W. F., Mueller-Dieckmann, H. J. M., Schulze-Gahmen, U., Worland, P., Sausville, E., and Kim, S. H. Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase. Proc. Natl. Acad. Sci. USA, 93: 2735-2740, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2735-2740
-
-
De Azevedo, W.F.1
Mueller-Dieckmann, H.J.M.2
Schulze-Gahmen, U.3
Worland, P.4
Sausville, E.5
Kim, S.H.6
-
31
-
-
0026452974
-
Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275
-
Kaur, G., Stetler-Stevenson, M., Sebers, S., Worland, P., Sedlacek, H., Myers, C., Czech, J., Naik, R., and Sausville, E. A. Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275. J. Natl. Cancer Inst., 84: 1736-1740, 1992.
-
(1992)
J. Natl. Cancer Inst.
, vol.84
, pp. 1736-1740
-
-
Kaur, G.1
Stetler-Stevenson, M.2
Sebers, S.3
Worland, P.4
Sedlacek, H.5
Myers, C.6
Czech, J.7
Naik, R.8
Sausville, E.A.9
-
32
-
-
0032055497
-
Flavopiridol induces apoptosis of normal lymphoid cells, causes immunosuppression and has potent antitumor activity in vivo against human leukemia and lymphoma xenografts
-
Arguello, F., Alexander, M., Sterry, J. A., Tudor, G., Smith, E. M., Kalavar, N. T., Greene, J. F., Koss, W., Morgan, C. D., Stinson, S. F., Siford, T. J., Alvord, W. G., Klabansky, R. L., and Sausville, E. A. Flavopiridol induces apoptosis of normal lymphoid cells, causes immunosuppression and has potent antitumor activity in vivo against human leukemia and lymphoma xenografts. Blood, 91: 2482-2490, 1998.
-
(1998)
Blood
, vol.91
, pp. 2482-2490
-
-
Arguello, F.1
Alexander, M.2
Sterry, J.A.3
Tudor, G.4
Smith, E.M.5
Kalavar, N.T.6
Greene, J.F.7
Koss, W.8
Morgan, C.D.9
Stinson, S.F.10
Siford, T.J.11
Alvord, W.G.12
Klabansky, R.L.13
Sausville, E.A.14
-
33
-
-
0031019034
-
Flavopiridol (L86-8275): Selective antitumor activity in vitro and activity in vivo in prostate carcinoma cells
-
Drees, M., Dengler, W. A., Roth, T., Labonte, H., Mayo, J., Malspeis, L., Grever, M., Sausville, E. A., and Fiebig, H. H. Flavopiridol (L86-8275): selective antitumor activity in vitro and activity in vivo in prostate carcinoma cells. Clin. Cancer Res., 3: 273-279, 1997.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 273-279
-
-
Drees, M.1
Dengler, W.A.2
Roth, T.3
Labonte, H.4
Mayo, J.5
Malspeis, L.6
Grever, M.7
Sausville, E.A.8
Fiebig, H.H.9
-
34
-
-
0032212885
-
Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis
-
Patel, V., Senderowicz, A. M., Pinto, J., D., Igishi, T., Raffeld, M., Quintanilla-Martinez, L., Ensley, J. F., Sausville, E. A., and Gutkind, J. S. Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis. J. Clin. Investig., 102: 1674-1681, 1998.
-
(1998)
J. Clin. Investig.
, vol.102
, pp. 1674-1681
-
-
Patel, V.1
Senderowicz, A.M.2
Pinto, J.D.3
Igishi, T.4
Raffeld, M.5
Quintanilla-Martinez, L.6
Ensley, J.F.7
Sausville, E.A.8
Gutkind, J.S.9
-
35
-
-
0029904810
-
Flavopiridol: A cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells
-
Bible, K. C., and Kaufmann, S. H. Flavopiridol: a cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells. Cancer Res., 56: 4856-4861, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 4856-4861
-
-
Bible, K.C.1
Kaufmann, S.H.2
-
36
-
-
0031963058
-
Early induction of apoptosis in hematopoietic cell lines after exposure to flavopiridol
-
Parker, B. W., Kaur, G., Nieves-Neira, W., Taimi, M., Kohlhagen, G., Shimizu, T., Losiewicz, M. D., Pommier, Y., Sausville, E. A., and Senderowicz, A. M. Early induction of apoptosis in hematopoietic cell lines after exposure to flavopiridol. Blood, 91: 458-465, 1998.
-
(1998)
Blood
, vol.91
, pp. 458-465
-
-
Parker, B.W.1
Kaur, G.2
Nieves-Neira, W.3
Taimi, M.4
Kohlhagen, G.5
Shimizu, T.6
Losiewicz, M.D.7
Pommier, Y.8
Sausville, E.A.9
Senderowicz, A.M.10
-
37
-
-
0040932434
-
The novel cyclin-dependent kinase inhibitor flavopiridol downregulates Bcl-2 and induces growth arrest and apoptosis in chronic B-cell leukemia lines
-
König, A., Schwarz, G. K., Mohammed, R. M., Al-Katib, A., and Gabrilove, J. The novel cyclin-dependent kinase inhibitor flavopiridol downregulates Bcl-2 and induces growth arrest and apoptosis in chronic B-cell leukemia lines. Blood, 90: 4307-4312, 1997.
-
(1997)
Blood
, vol.90
, pp. 4307-4312
-
-
König, A.1
Schwarz, G.K.2
Mohammed, R.M.3
Al-Katib, A.4
Gabrilove, J.5
-
38
-
-
0031725137
-
Flavopiridol mediates cell cycle arrest and apoptosis in esophageal cancer cells
-
Schrump, D. S., Matthews, W., Chen, G. A., Mixon, A., and Altorki, N. K. Flavopiridol mediates cell cycle arrest and apoptosis in esophageal cancer cells. Clin. Cancer Res., 4: 2885-2890, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 2885-2890
-
-
Schrump, D.S.1
Matthews, W.2
Chen, G.A.3
Mixon, A.4
Altorki, N.K.5
-
39
-
-
0031670668
-
Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms
-
Senderowicz, A. M., Headlee, D., Stinson, S. F., Lush, R. M., Kalil, N., Villalba, L., Hill, K., Steinberg, S. M., Figg, W. D., Tompkins, A., Arbuck, S. G., and Sausville, E. A. Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms. J. Clin. Oncol., 16: 2986-2999, 1998.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 2986-2999
-
-
Senderowicz, A.M.1
Headlee, D.2
Stinson, S.F.3
Lush, R.M.4
Kalil, N.5
Villalba, L.6
Hill, K.7
Steinberg, S.M.8
Figg, W.D.9
Tompkins, A.10
Arbuck, S.G.11
Sausville, E.A.12
-
40
-
-
0028070540
-
RB protein status and clinical correlation from 171 cell lines representing lung cancer, extrapulmonary small cell carcinoma, and mesothelioma
-
Shimizu, E., Coxon, A., Otterson, G. A., Steinberg, S. M. Kratzke, R. A., Kim, Y. W., Fedorko, J., Oie, H., Johnson, B. E., Mulshine, J. L., Minna, J. D., Gazdar, A. F., and Kaye, F. J. RB protein status and clinical correlation from 171 cell lines representing lung cancer, extrapulmonary small cell carcinoma, and mesothelioma. Oncogene, 9: 2441-2448, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 2441-2448
-
-
Shimizu, E.1
Coxon, A.2
Otterson, G.A.3
Steinberg, S.M.4
Kratzke, R.A.5
Kim, Y.W.6
Fedorko, J.7
Oie, H.8
Johnson, B.E.9
Mulshine, J.L.10
Minna, J.D.11
Gazdar, A.F.12
Kaye, F.J.13
-
41
-
-
0028033270
-
INK4 in human cancer
-
INK4 in human cancer. Proc. Natl. Acad. Sci. USA, 91: 11045-11049, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11045-11049
-
-
Okamoto, A.1
Demetrick, D.J.2
Spillare, E.A.3
Hagiwara, K.4
Hussain, S.P.5
Bennett, W.P.6
Forrester, K.7
Gerwin, B.8
Serrano, M.9
Beach, D.10
-
42
-
-
0028987265
-
INK4B/MtS2, and p18 genes in primary and metastatic lung cancer
-
INK4B/MTS2, and p18 genes in primary and metastatic lung cancer. Cancer Res., 55: 1448-1451, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 1448-1451
-
-
Okamoto, A.1
Hussain, S.P.2
Hagiwara, K.3
Spillare, E.4
Rusin, M.R.5
Demetrick, D.J.6
Serrano, M.7
Hannon, G.J.8
Shiseki, M.9
Zariwala, M.10
Xiong, Y.11
Beach, D.H.12
Yokota, J.13
Harris, C.C.14
-
43
-
-
0028840446
-
Alterations of CDKN2 (p16) in non-small cell lung cancer
-
de Vos, S., Miller, C. W., Takeuchi, S., Gombart, A. F., Cho, S. K., and Koeffler, H. P. Alterations of CDKN2 (p16) in non-small cell lung cancer. Genes Chromosomes Cancer, 14: 164-170, 1995.
-
(1995)
Genes Chromosomes Cancer
, vol.14
, pp. 164-170
-
-
De Vos, S.1
Miller, C.W.2
Takeuchi, S.3
Gombart, A.F.4
Cho, S.K.5
Koeffler, H.P.6
-
44
-
-
0028971961
-
INK4A inactivation in non-small cell lung cancer cell lines
-
INK4A inactivation in non-small cell lung cancer cell lines. Cancer Res., 55: 6200-6209, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 6200-6209
-
-
Shapiro, G.I.1
Park, J.E.2
Edwards, C.D.3
Mao, L.4
Sidransky, D.5
Ewen, M.E.6
Rollins, B.J.7
-
45
-
-
0026397676
-
P53 mutations, ras mutations, and p53-heast shock 70 protein complexes in human lung carcinoma cell lines
-
Lehman, T. A., Bennett, W. P., Metcalf, R. A., Welsh, J. A., Ecker, J., Modali, R. V., Ullrich, S., Romano, J. W., Appella, E., Testa, J. R., Gerwin, B. I., and Harris, C. C. p53 mutations, ras mutations, and p53-heast shock 70 protein complexes in human lung carcinoma cell lines. Cancer Res., 51: 4090-4096, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 4090-4096
-
-
Lehman, T.A.1
Bennett, W.P.2
Metcalf, R.A.3
Welsh, J.A.4
Ecker, J.5
Modali, R.V.6
Ullrich, S.7
Romano, J.W.8
Appella, E.9
Testa, J.R.10
Gerwin, B.I.11
Harris, C.C.12
-
46
-
-
0026051751
-
Detection of p53 in primary lung tumors and non-small cell lung carcinoma cell lines
-
Caamano, J., Ruggeri, B., Momiki, S., Sickler, A., Zhang, S. Y., and Klein-Szanto, A. J. Detection of p53 in primary lung tumors and non-small cell lung carcinoma cell lines. Am. J. Pathol., 139: 839-845, 1991.
-
(1991)
Am. J. Pathol.
, vol.139
, pp. 839-845
-
-
Caamano, J.1
Ruggeri, B.2
Momiki, S.3
Sickler, A.4
Zhang, S.Y.5
Klein-Szanto, A.J.6
-
47
-
-
0026543204
-
P53 gene mutations in non-small cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features
-
Mitsudomi, T., Steinberg, S. M., Nau, M. M., Carbone, D., D'Amico, D., Bodner, S., Oie, H. K., Linnoila, R. I., Mulshine, J. L., Minna, J. D., and Gazdar, A. F. p53 gene mutations in non-small cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features. Oncogene, 7: 171-180, 1992.
-
(1992)
Oncogene
, vol.7
, pp. 171-180
-
-
Mitsudomi, T.1
Steinberg, S.M.2
Nau, M.M.3
Carbone, D.4
D'Amico, D.5
Bodner, S.6
Oie, H.K.7
Linnoila, R.I.8
Mulshine, J.L.9
Minna, J.D.10
Gazdar, A.F.11
-
48
-
-
12644305917
-
Analysis of K-ras, p53, bcl-2 and Rb expression in non-small cell lung cancer cell lines
-
Loprevite, M., Varesco, L., Favoni, R., Ferrara, G. B., Moro, F., Ottaggio, L., Fronza, G., Campomenosi, P., Abbondandolo, A., Cutrona, G., Roncella, S., Albini, A., Aluigi, M. G., Pozzi, S., Pera, C., Biticchi, R., Gismondi, V., Grossi, F., Pennucci, M. C., and Ardizzoni, A. Analysis of K-ras, p53, bcl-2 and Rb expression in non-small cell lung cancer cell lines. Int. J. Oncol., 11: 1203-1208, 1997.
-
(1997)
Int. J. Oncol.
, vol.11
, pp. 1203-1208
-
-
Loprevite, M.1
Varesco, L.2
Favoni, R.3
Ferrara, G.B.4
Moro, F.5
Ottaggio, L.6
Fronza, G.7
Campomenosi, P.8
Abbondandolo, A.9
Cutrona, G.10
Roncella, S.11
Albini, A.12
Aluigi, M.G.13
Pozzi, S.14
Pera, C.15
Biticchi, R.16
Gismondi, V.17
Grossi, F.18
Pennucci, M.C.19
Ardizzoni, A.20
more..
-
49
-
-
0026024632
-
The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells
-
Halbert, C. I., Demers, G. W., and Galloway, D. A. The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells. J. Virol., 65: 473-478, 1991.
-
(1991)
J. Virol.
, vol.65
, pp. 473-478
-
-
Halbert, C.I.1
Demers, G.W.2
Galloway, D.A.3
-
50
-
-
0028985932
-
1 checkpoint-competent cells
-
1 checkpoint-competent cells. Cancer Res., 55: 1639-1642, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 1639-1642
-
-
Russell, K.J.1
Wiens, L.W.2
Demers, G.W.3
Galloway, D.A.4
Plon, S.E.5
Groudine, M.6
-
51
-
-
0027255417
-
Specific proteolytic cleave of poly (ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
-
Kaufmann, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E., and Poirier, G. G. Specific proteolytic cleave of poly (ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res., S3: 3976-3985, 1993.
-
(1993)
Cancer Res.
, vol.S3
, pp. 3976-3985
-
-
Kaufmann, S.H.1
Desnoyers, S.2
Ottaviano, Y.3
Davidson, N.E.4
Poirier, G.G.5
-
52
-
-
0032563286
-
Cip1/Waf1 by caspases is an early event during DNA damage-induced apoptosis
-
Cip1/Waf1 by caspases is an early event during DNA damage-induced apoptosis. J. Biol. Chem., 273: 19207-19212, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19207-19212
-
-
Gervais, J.L.M.1
Seth, P.2
Zhang, H.3
-
53
-
-
0032012062
-
Kip1 mediates apoptosis in endothelial cells through activation of cdk2: Role of a caspase cascade
-
Kip1 mediates apoptosis in endothelial cells through activation of cdk2: role of a caspase cascade. Mol. Cell, 1: 553-563, 1998.
-
(1998)
Mol. Cell
, vol.1
, pp. 553-563
-
-
Levkau, B.1
Koyama, H.2
Raines, E.W.3
Clurman, B.E.4
Herren, B.5
Orth, K.6
Roberts, J.M.7
Ross, R.8
-
54
-
-
0033521889
-
Cip1/Waf1 converts cancer cells from growth arrest to undergoing apoptosis
-
Cip1/Waf1 converts cancer cells from growth arrest to undergoing apoptosis. Oncogene, 18: 1131-1138, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 1131-1138
-
-
Zhang, Y.1
Fujita, N.2
Tsuruo, T.3
-
55
-
-
0032538532
-
Promoter activation and following induction of the p21/WAF1 gene by flavone is involved in G1 phase arrest in A549 lung adenocarcinoma cells
-
Bai, F., Matsui, T., Ohtani-Fujita, N., Matsukawa, Y., Ding, Y., and Sakai, T. Promoter activation and following induction of the p21/WAF1 gene by flavone is involved in G1 phase arrest in A549 lung adenocarcinoma cells. FEBS Lett., 437: 61-64, 1998.
-
(1998)
FEBS Lett.
, vol.437
, pp. 61-64
-
-
Bai, F.1
Matsui, T.2
Ohtani-Fujita, N.3
Matsukawa, Y.4
Ding, Y.5
Sakai, T.6
-
56
-
-
0029912852
-
Flavonoids activate wild-type p53
-
Plaumann, B., Fritsche, M., Rimpler, H., Brandner, G., and Hess, R. D. Flavonoids activate wild-type p53. Oncogene, 13: 1605-1614, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 1605-1614
-
-
Plaumann, B.1
Fritsche, M.2
Rimpler, H.3
Brandner, G.4
Hess, R.D.5
-
57
-
-
0030796989
-
Induction of p21/WAF1 and G1 cell-cycle arrest by the chemopreventive agent apigenin
-
Lepley, D. M., and Pelling, J. C. Induction of p21/WAF1 and G1 cell-cycle arrest by the chemopreventive agent apigenin. Mol. Carcinog., 19: 74-82, 1997.
-
(1997)
Mol. Carcinog.
, vol.19
, pp. 74-82
-
-
Lepley, D.M.1
Pelling, J.C.2
-
58
-
-
0028108990
-
Induction of apoptosis by quercetin: Involvement of heat shock protein
-
Wei, Y., Zhao, X., Kariya, Y., Fukata, H., Teshigawara, K., and Uchida, A. Induction of apoptosis by quercetin: involvement of heat shock protein. Cancer Res., 54: 4952-4957, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 4952-4957
-
-
Wei, Y.1
Zhao, X.2
Kariya, Y.3
Fukata, H.4
Teshigawara, K.5
Uchida, A.6
-
59
-
-
0040379168
-
Cell cycle-independent induction of apoptosis by the anti-tumor drug flavopiridol in endothelial cells
-
Brüsselbach, S., Nettelbeck, D. M., Sedlacek, H. H., and Müller, R. Cell cycle-independent induction of apoptosis by the anti-tumor drug flavopiridol in endothelial cells. Int. J. Cancer, 77: 146-152, 1998.
-
(1998)
Int. J. Cancer
, vol.77
, pp. 146-152
-
-
Brüsselbach, S.1
Nettelbeck, D.M.2
Sedlacek, H.H.3
Müller, R.4
-
60
-
-
0005355001
-
Cell cycle arrest and apoptosis in NSCLC cell lines by cyclin-dependent kinase inhibitor, flavopiridol
-
Kaur, G., Hursey, M., and Sausville, E. A. Cell cycle arrest and apoptosis in NSCLC cell lines by cyclin-dependent kinase inhibitor, flavopiridol. Proc. Am. Assoc. Cancer Res., 39: A4118, 1998.
-
(1998)
Proc. Am. Assoc. Cancer Res.
, vol.39
-
-
Kaur, G.1
Hursey, M.2
Sausville, E.A.3
-
61
-
-
0030812207
-
Cytotoxic synergy between flavopiridol and various antineoplastic agents: The importance of sequence of administration
-
Bible, K. C., and Kaufmann, S. H. Cytotoxic synergy between flavopiridol and various antineoplastic agents: the importance of sequence of administration. Cancer Res., 57: 3375-3380, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 3375-3380
-
-
Bible, K.C.1
Kaufmann, S.H.2
-
62
-
-
0030824869
-
Potentiation of apoptosis by flavopiridol in mitomycin C-treated gastric and breast cancer cells
-
Schwartz, G. K., Farsi, K., Maslak, P., Kelsen, D. P., and Spriggs, D. Potentiation of apoptosis by flavopiridol in mitomycin C-treated gastric and breast cancer cells. Clin. Cancer Res., 3: 1467-1472, 1997.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 1467-1472
-
-
Schwartz, G.K.1
Farsi, K.2
Maslak, P.3
Kelsen, D.P.4
Spriggs, D.5
|