-
1
-
-
0345398627
-
A Phase I trial of a novel cyclic-dependent kinase inhibitor flavopiridol in patients with refractory neoplasms
-
Senderowicz, A. M., Headlee, D., Stinson, S., Lush, R. M., Figg, W. D., Pluda, J., and Sausville, E. A Phase I trial of a novel cyclic-dependent kinase inhibitor flavopiridol in patients with refractory neoplasms. Proc. Am. Soc. Clin. Oncol., 16: 226a, 1997.
-
(1997)
Proc. Am. Soc. Clin. Oncol.
, vol.16
-
-
Senderowicz, A.M.1
Headlee, D.2
Stinson, S.3
Lush, R.M.4
Figg, W.D.5
Pluda, J.6
Sausville, E.7
-
2
-
-
0023924162
-
An anti-inflammatory cum immunomodulatory piperidinylhenzopyranone from Dysoxylum binectariferum: Isolation, structure and total synthesis
-
Maik, R. G., Kattice, S. L., Bhat, S. V., Alreja, B., De Souza, N. J., and Rupp, R. H. An anti-inflammatory cum immunomodulatory piperidinylhenzopyranone from Dysoxylum binectariferum: isolation, structure and total synthesis. Tetrahedron, 44: 2081-2086, 1988.
-
(1988)
Tetrahedron
, vol.44
, pp. 2081-2086
-
-
Maik, R.G.1
Kattice, S.L.2
Bhat, S.V.3
Alreja, B.4
De Souza, N.J.5
Rupp, R.H.6
-
3
-
-
0026452974
-
Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275
-
Kaur, G., Stelter-Stevenson, M., Sebers, S., Worland, P., Sedlacek, H., Myers, C., Czech, J., Naik, R., and Sausville, E. Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275. J. Natl. Cancer Inst., 84: 1736-1740, 1992.
-
(1992)
J. Natl. Cancer Inst.
, vol.84
, pp. 1736-1740
-
-
Kaur, G.1
Stelter-Stevenson, M.2
Sebers, S.3
Worland, P.4
Sedlacek, H.5
Myers, C.6
Czech, J.7
Naik, R.8
Sausville, E.9
-
4
-
-
0000201912
-
DNA fragmentation and apoptosis of lymphoma and prostate cancer cell lines after flavopiridol treatment
-
Parker, B. W., Senderowicz, A. M., Nieves-Neira, W., Pommier, Y., and Sausville, E. A. DNA fragmentation and apoptosis of lymphoma and prostate cancer cell lines after flavopiridol treatment. Proc. Am. Assoc. Cancer Res., 37: 398, 1996.
-
(1996)
Proc. Am. Assoc. Cancer Res.
, vol.37
, pp. 398
-
-
Parker, B.W.1
Senderowicz, A.M.2
Nieves-Neira, W.3
Pommier, Y.4
Sausville, E.A.5
-
5
-
-
0031019034
-
Flavopiridol (L86-8275): Selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells
-
Drees, M., Dengle, W. A., Roth, T., Labonte, H., May, J., Malspeis, L., Grever, M., Sausville, E. A., and Fiebig, H. H. Flavopiridol (L86-8275): selective antitumor activity in vitro and activity in vivo for prostate carcinoma cells. Clin. Cancer Res., 3: 273-279, 1997.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 273-279
-
-
Drees, M.1
Dengle, W.A.2
Roth, T.3
Labonte, H.4
May, J.5
Malspeis, L.6
Grever, M.7
Sausville, E.A.8
Fiebig, H.H.9
-
6
-
-
0029904810
-
Flavopiridol. A cytotoxic flavone that induces cell death in noncycling A549 human luna carcinoma cells
-
Bible, K. C., and Kaufmann, S. H. Flavopiridol. A cytotoxic flavone that induces cell death in noncycling A549 human luna carcinoma cells. Cancer Res., 56: 4856-4861, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 4856-4861
-
-
Bible, K.C.1
Kaufmann, S.H.2
-
7
-
-
0028176485
-
Potent inhibition of cdc2 kinase activity by the flavonoid L86-8275
-
Losiewicz, M. D., Carlson, B. A., Kaur, G., Sausville, E. A., and Worland, P. J. Potent inhibition of cdc2 kinase activity by the flavonoid L86-8275. Biochem. Biophys. Res. Commun., 201: 589-595, 1994.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.201
, pp. 589-595
-
-
Losiewicz, M.D.1
Carlson, B.A.2
Kaur, G.3
Sausville, E.A.4
Worland, P.J.5
-
9
-
-
0027433237
-
Alteration of the phosphorylation state or p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells
-
Worland, P. J., Kaur, G., and Stetler-Stevenson, M. Alteration of the phosphorylation state or p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells. Biochem. Pharmacol., 46: 1831-1840, 1993.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 1831-1840
-
-
Worland, P.J.1
Kaur, G.2
Stetler-Stevenson, M.3
-
10
-
-
0028046589
-
Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells
-
Jarvis, W. D., Fornari, F. A., Browning, J. L., Gerwitz, D. A., Kolesnick, R. N., and Grant, S. Attenuation of ceramide-induced apoptosis by diglyceride in human myeloid leukemia cells. J. Biol. Chem., 268: 31685-31692, 1994.
-
(1994)
J. Biol. Chem.
, vol.268
, pp. 31685-31692
-
-
Jarvis, W.D.1
Fornari, F.A.2
Browning, J.L.3
Gerwitz, D.A.4
Kolesnick, R.N.5
Grant, S.6
-
11
-
-
0027511687
-
Programmed cell death induced by ceramide
-
Washington DC
-
Obeid, L. M., Linardic, C. M., Karolak, L. A., and Hannun, Y. A. Programmed cell death induced by ceramide. Science (Washington DC), 259: 1769-1771, 1993.
-
(1993)
Science
, vol.259
, pp. 1769-1771
-
-
Obeid, L.M.1
Linardic, C.M.2
Karolak, L.A.3
Hannun, Y.A.4
-
12
-
-
0028316195
-
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C
-
Jarvis, W. D., Turner, A. J., Povirk, L. F., Taylor, R. S., and Grant, S. Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. Cancer Res., 54: 1707-1714, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 1707-1714
-
-
Jarvis, W.D.1
Turner, A.J.2
Povirk, L.F.3
Taylor, R.S.4
Grant, S.5
-
13
-
-
0028287960
-
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis
-
Haimovitz-Friedman, A., Chu-Cheng, K., Ehleiter, D., and Persaud, R. S. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J. Exp. Med., 180: 525-535, 1994.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 525-535
-
-
Haimovitz-Friedman, A.1
Chu-Cheng, K.2
Ehleiter, D.3
Persaud, R.S.4
-
14
-
-
0029001975
-
Protein kinase C involvement in apoptosis
-
Lucas, M., and Sanchez-Margalet, V. Protein kinase C involvement in apoptosis. Gen. Pharmacol., 26: 881-887, 1995.
-
(1995)
Gen. Pharmacol.
, vol.26
, pp. 881-887
-
-
Lucas, M.1
Sanchez-Margalet, V.2
-
15
-
-
0029166590
-
Potentiation of apoptosis by treatment with the protein kinase C specific inhibitor safingol in mitomycin-C treated gastric cancer cells
-
Schwartz, G. K., Haimovitz-Friedman, A., Dhupar, S. K., Ehleiter, D., Maslak, P., Lai, L., Laganzo, L., Kelsen, D. P., Fuks, Z., and Albino, A. P. Potentiation of apoptosis by treatment with the protein kinase C specific inhibitor safingol in mitomycin-C treated gastric cancer cells. J. Natl. Cancer Inst., 87: 1394-1399, 1995.
-
(1995)
J. Natl. Cancer Inst.
, vol.87
, pp. 1394-1399
-
-
Schwartz, G.K.1
Haimovitz-Friedman, A.2
Dhupar, S.K.3
Ehleiter, D.4
Maslak, P.5
Lai, L.6
Laganzo, L.7
Kelsen, D.P.8
Fuks, Z.9
Albino, A.P.10
-
16
-
-
0027255417
-
Specific proteolytic fragmentation of poly(ADP-ribose) polymerase. An early marker of chemotherapy-induced apoptosis
-
Kaufmann, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N., and Poirier, G. G. Specific proteolytic fragmentation of poly(ADP-ribose) polymerase. An early marker of chemotherapy-induced apoptosis. Cancer Res., 53: 3976-3985, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 3976-3985
-
-
Kaufmann, S.H.1
Desnoyers, S.2
Ottaviano, Y.3
Davidson, N.4
Poirier, G.G.5
-
17
-
-
0028820893
-
Application of biotin, digoxigenin, or fluorescein conjugated deoxynucleotides to label DNA strand breaks for analysis of cell proliferation and apoptosis using flow cytometry
-
Li, X., James, W., Traganos, F., and Darzynkiewicz, Z. Application of biotin, digoxigenin, or fluorescein conjugated deoxynucleotides to label DNA strand breaks for analysis of cell proliferation and apoptosis using flow cytometry. Biotech. Histochem., 70(5): 234-241, 1995.
-
(1995)
Biotech. Histochem.
, vol.70
, Issue.5
, pp. 234-241
-
-
Li, X.1
James, W.2
Traganos, F.3
Darzynkiewicz, Z.4
-
18
-
-
4244066474
-
The protein kinase C (PKC) inhibitor safingol (SAF) restores Mitomycin-C (MMC)-induced loss of PKCα and PKCε expression in association with the induction of apoptosis
-
Danso, D., Farsi, K., Greaney, C., Spriggs, D., Kelsen, D. K., and Schwartz, G. K. The protein kinase C (PKC) inhibitor safingol (SAF) restores Mitomycin-C (MMC)-induced loss of PKCα and PKCε expression in association with the induction of apoptosis. Proc. Am. Assoc. Cancer Res., 38: 194, 1997.
-
(1997)
Proc. Am. Assoc. Cancer Res.
, vol.38
, pp. 194
-
-
Danso, D.1
Farsi, K.2
Greaney, C.3
Spriggs, D.4
Kelsen, D.K.5
Schwartz, G.K.6
-
19
-
-
0028818126
-
Bcl-2 expression delays drug-induced apoptosis but does not increase clonogenic survival after drug treatment in HeLa cells
-
Yin, D. X., and Shimke, R. T. Bcl-2 expression delays drug-induced apoptosis but does not increase clonogenic survival after drug treatment in HeLa cells. Cancer Res., 55: 4922-4928, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4922-4928
-
-
Yin, D.X.1
Shimke, R.T.2
-
20
-
-
0019225636
-
Cell death: The significance of apoptosis
-
Wylie, A. H., Kerr, J. F. R., and Currie, A. R. Cell death: the significance of apoptosis. Int. Rev. Cytol., 68: 251-306, 1990.
-
(1990)
Int. Rev. Cytol.
, vol.68
, pp. 251-306
-
-
Wylie, A.H.1
Kerr, J.F.R.2
Currie, A.R.3
-
21
-
-
0028910555
-
The mutational status of p53 protein in gastric and esophageal adenocarcinorna cell lines predicts sensitivity to chemotherapeutic agents
-
Nabeya, Y., Loganzo, F., Maslak, P., Lai, L., DeOliveira, A., Schwanz, G. K., Blundell, M. L., Altorki, N. K., Kelsen, D. P., and Albino, A. P. The mutational status of p53 protein in gastric and esophageal adenocarcinorna cell lines predicts sensitivity to chemotherapeutic agents. Int. J. Cancer Predict. Oncol., 64: 1-10, 1995.
-
(1995)
Int. J. Cancer Predict. Oncol.
, vol.64
, pp. 1-10
-
-
Nabeya, Y.1
Loganzo, F.2
Maslak, P.3
Lai, L.4
DeOliveira, A.5
Schwanz, G.K.6
Blundell, M.L.7
Altorki, N.K.8
Kelsen, D.P.9
Albino, A.P.10
-
22
-
-
0025367297
-
Genetic and immunochemical analysis of mutant p53 in human breast cancer cells lines
-
Bartek, J., Iggo, R., Gannon, J., and Lane, D. P. Genetic and immunochemical analysis of mutant p53 in human breast cancer cells lines. Oncogene, 5: 893-899, 1990.
-
(1990)
Oncogene
, vol.5
, pp. 893-899
-
-
Bartek, J.1
Iggo, R.2
Gannon, J.3
Lane, D.P.4
-
23
-
-
0004325924
-
The enhancement of chemotherapy-induced apoptosis by flavopiridol (flavo) in gastric cancer cells is sequence dependent
-
Werner, J. L., Greaney, C., Spriggs, D., Kelsen, D. K., and Schwartz, G. K. The enhancement of chemotherapy-induced apoptosis by flavopiridol (flavo) in gastric cancer cells is sequence dependent. Proc. Am. Soc. Clin. Oncol., 16: 547a, 1997.
-
(1997)
Proc. Am. Soc. Clin. Oncol.
, vol.16
-
-
Werner, J.L.1
Greaney, C.2
Spriggs, D.3
Kelsen, D.K.4
Schwartz, G.K.5
|