Faculty induction of blood-brain barrier functions by astrocytes isolated from stroke-prone spontaneously hypertensive rats

Clinical and Experimental Pharmacology and Physiology

Volumn 24, Issue 9-10, 1997, Pages 686-691

  Yamagata, Kazuo ^a,e   Tagami, Motoki ^a,d   Nara, Yasuo ^c   Fujino, Hideaki ^a   Kuhota, Akiyoshi ^a   Numano, Fujio ^a   Kato, Taiji ^b   Yamori, Yukio ^c  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^c Kyoto University   (Japan)

^d Sanraku Hospital   (Japan)

^e UNIVERSITY OF EAST ASIA   (Japan)

Author keywords

Astrocyte; Blood brain barrier; Co culture; Endothelial cell; Stroke prone spontaneously hypertensive rats; Tight junction; Ultrastructure

Indexed keywords

LACTIC ACID; PYRUVIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN INJURY; BRAIN ISCHEMIA; CELL ISOLATION; CELL STRUCTURE; CELL SWELLING; COCULTURE; CONTROLLED STUDY; CYTOLOGY; ENDOTHELIUM CELL; NONHUMAN; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; ANIMAL; CELL CULTURE; CEREBROVASCULAR DISEASE; COMPARATIVE STUDY; ELECTRIC CONDUCTIVITY; ELECTRON MICROSCOPY; GENETICS; HYPERTENSION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; ULTRASTRUCTURE; WISTAR KYOTO RAT;

ANIMALS; ASTROCYTES; BLOOD-BRAIN BARRIER; CELLS, CULTURED; CEREBROVASCULAR DISORDERS; COCULTURE TECHNIQUES; ELECTRIC CONDUCTIVITY; HYPERTENSION; LACTIC ACID; MICROSCOPY, ELECTRON; PYRUVIC ACID; RATS; RATS, INBRED SHR; RATS, INBRED WKY;

EID: 0030610658     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1997.tb02113.x     Document Type: Article

References (25)

1. Yamori Y, Nagaoka A, Okamoto K. Importance of genetic factors in hypertensive cerebrovascular lesions. Jpn. Circ. J. 1974; 38: 1095-100.
2. Yamori Y. Predictive and preventive pathology of cardiovascular disease. Acta Pathol. Jpn. 1989; 39: 683-705.
3. Yamori Y. Development of the spontaneously hypertensive rats (SHR), the stroke-prone SHR (SHRSP) and their various substrain models for hypertension-related cardiovascular diseases. In: Ganten D, DeJong W (eds). Handbook of Hypertension, Vol. 16. Experimental and Genetic Models of Hypertension. Elsevier Science, Amsterdam. 1994; 346-64.
4. Tagami M, Nara Y, Kubota A et al. Ultrastructural characteristics of occluded perforating arteries in stroke-prone spontaneously hypertensive rats. Stroke 1987; 18: 733-40.
5. Tagami M, Nara Y, Kubota A, Fujino H, Yamori Y. Ultrastructural changes in cerebral pericytes and astrocytes of stroke-prone spontaneously hypertensive rats. Stroke 1990; 21: 106-17.
6. Janzer RC, Raff MC. Astrocytes induce blood-brain barrier properties in endothelial cells. Nature 1987; 325: 253-7.
7. Reese TS, Karnovsky MJ. Fine structural localization of a blood-brain barrier to exogenous peroxidase. J. Cell Biol. 1967; 3: 207-17.
8. Arthur FE, Shivers RR, Bowman DP. Astrocyte-mediated induction of tight junctions in brain capillary endothelium: An efficient in vitro model. Dev. Brain Res. 1987; 36: 155-9.
9. Beck WD, Roberts LR, Olson JJ. Glial cells influence membrane-associated enzyme activity at the blood-brain barrier. Brain Res. 1986; 381: 131-7.
10. Raub JT, Kuentzel LS, Sawada AG. Permeability of bovine brain macrovessel endothelial cells in vitro: Barrier tightening by factor released from astroglioma cells. Exp. Cell Res. 1992; 199: 330-40.
11. O'Donnell EM, Martinz A, Sun D. Cerebral microvascular endothelial cell Na-K-Cl cotransport: Regulation by astrocytes-conditioned medium. Am. J. Physiol. 1995; 268: C747-54.
12. Dehouck M-P, Fruchart J-C, Cecchelli R. Upregulation of the low density lipoprotein receptor at the blood-brain barrier: Intercommunications between brain capillary endothelial cells and astrocytes. J. Cell Biol. 1994; 26: 465-73.
13. Furukawa S, Furukawa Y, Satoyoshi E, Hayashi K. Synthesis and secretion of nerve growth factor by mouse astroglial cells in culture. Biochem. Biophys. Res. Commun. 1986; 136: 57-63.
14. Miller RH, Ffrench-Constant C, Raff MC. The macroglial cells of the rat optic nerve. Annu. Rev. Neurosci. 1989; 12: 517-34.
15. Okabe T, Yamagata K, Fujusawa M, Takaku F, Hidaka H, Umezawa Y. Induction by fibroblast growth factor of angiotensin converting enzyme in vascular endothelial cells in vitro. Biochem. Biophys. Res. Commun. 1987; 145: 1211-16.
16. Risau W, Dingler A, Albrecht U, Dehouck M-P, Cecchelli R. Blood-brain barrier pericytes are the main source of gamma-glutamyltranspeptidase activity in brain capillaries. J. Neurochem. 1992; 58: 667-72.
17. Karnovsky MJ. A formaldehyde-glutaraldehyde fixative of high osmolarity for use in electron microscopy. J. Cell Biol. 1965; 27: A137-8.
18. Tagami M, Yamagata K, Fujino H, Kubota A, Nara Y, Yamori Y. Morphological differentiation of endothelial cells co-cultured with astrocytes on type-I or type IV collagen. Cell Tissue Res. 1992; 268: 225-32.
19. Meyer J, Mischeck U, Veyhl M, Henzel K, Galla H-J. Blood-brain barrier characteristic enzymatic properties in cultured brain capillary endothelial cells. Brain Res. 1990; 514: 305-9.
20. Meyer J, Rauh J, Galla H-J. The susceptibility of cerebral endothelial cells to astroglial induction of blood-brain barrier enzymes depends on their proliferative state. J. Neurochem. 1991; 57: 1971-7.
21. Werber HW, Fitch-burke MP. Pial venous pressure and acute hypertensive disruption of the blood-brain barrier in spontaneously and renal hypertension. Brain Res. 1990; 515: 235-40.
22. Chistian FD, Jin-Sheng Li, Emesto LS, Sharon AW. Hypertension induced by brain grafts from fetal spontaneously hypertensive rats. Hypertension 1994; 23: 765-73.
23. Yamagata K, Nara Y, Tagami M, Yamori Y. Demonstration of hereditary accelerated proliferation in astrocytes derived from spontaneously hypertensive rats. Clin. Exp. Pharmacol. Phvsiol. 1995; 22: 605-9.
24. Kraig RP, Chesler M. Astrocytic acidosis in hyperglycemic and complete ischemia. J. Cereb. Blood Flow Metab. 1990; 10: 104-14.
25. Staub F, Baethmann A, Peters J, Weight H, Kempski O. Effects of lactic acidosis on glial cell volume and viability. J. Cereb. Blood Flow Metab. 1990; 10: 866-76.