The influence of cytokines on the integrity of the blood-brain barrier in vitro

Journal of Neuroimmunology

Volumn 64, Issue 1, 1996, Pages 37-43

  De Vries, Helga E ^a   Blom Roosemalen, Margret C M ^a   Van Oosten, Marijke ^a   De Boer, Albert G ^a   Van Berkel, Theo J C ^a   Breimer, Douwe D ^a   Kuiper, Johan ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Blood brain barrier; Cerebral endothelial cells; Cytokines; Inflammation

Indexed keywords

INDOMETACIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; CONTROLLED STUDY; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR ENDOTHELIUM;

EID: 0030034301     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-5728(95)00148-4     Document Type: Article

References (31)

1. Aggarwal, B.B., Eessalu, T.E. and Mass, P.E. (1985) Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon. Nature 318, 665-667.
2. Benveniste, E.N., Sparacio, S.M., Noms, J.G., Grenett, H.E. and Fuller, G.M. (1990) Induction and regulation of interleukin-6 gene expression in rat astrocytes. J. Neuroimmunol. 30, 201-212.
3. Camussi, G., Albano, E., Tetta, C. and Bussolino, F. (1991) The molecular action of tumor necrosis factor-α. Eur. J. Biochem. 202, 3-14.
4. 2 activating protein in endothelial cells. Biochem. J. 250, 125-131.
5. Claudio, L., Martiney, J.A. and Brosnan, C.F. (1994) Ultrastructural studies of the blood-retina barrier after exposure to interleukin-1 β or tumor necrosis factor α. Lab. Invest. 70, 850-861.
6. Dascombe, M.J. (1985) The pharmacology of fever. Progr. Neurobiol. 25, 327-373.
7. De Vries, H.E., Blom-Roosmalen, M.C.M., De Boer, A.C., Breimer, D.D., Van Berkel, Th. J.C. and Kuiper, J. (1995a) Effects of bacterial endotoxin on bovine cerebral endothelial cell layers in vitro. J. Pharmacol. Exp. Ther., in press.
8. De Vries, H.E., Hoogendoorn, K.H., Van Dijk, J., Zijlstra, F.J., Breimer, D.D., Van Berkel, Th.J.C., De Boer, A.G., Van Dam, A.-M. and Kuiper, J. (1995b) Eicosanoid production by rat cerebral endothelial cells in vitro: stimulation by lipopolysaccharide, interleukin-1 and interleukin-6. J. Neuroimmunol. 59, 1-8.
9. Dinarello, C.A. (1988) Biology of interleukin 1. FASEB J. 2, 108-115.
10. Fong, Y., Tracey, K.J., Moldawer, L.L., Hesse, D.G., Manogue, K.B., Kenney, J.S., Lee, A.T., Kuo, G.C., Allison, A.C., Lowrey, S.F. and Cerami, A. (1989) Antibodies to cachectin/tumor necrosis factor reduce interleukin-1 α and interleukin-6 during lethal shock. J. Exp. Med. 170, 1627-1633.
11. Gallo, P., Frei, K., Rordorf, C., Lazdins, J., Tavolato, B. and Fontana, A. (1989) Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in cerebrospinal fluid. J. Neuroimmunol. 23, 109-116.
12. Gijbels, K., Van Damme, J., Proost, P., Put, W., Carton, H. and Billiau, A. (1990) Interleukin-6 production in the central nervous system during EAE. Eur. J. Immunol. 20, 233-235.
13. Glenner, G.G. and Wong, C.W. (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 120, 885-890.
14. Gottschall, P.E., Tatsuno, I. and Arimura, A. (1994) Regulation of interleukin-6 (IL-6) secretion in primary cultured rat astrocytes: synergism of interleukin-1 (IL-1) and pituitary adenylate cyclase activating polypeptide (PACAP). Brain Res. 637, 197-203.
15. Hartung, H.P., Jung, S., Zielasek, J., Schmidt, B., Archelos, J.J. and Toyka, K.V. (1992) Inflammatory mediators in demyelinating disorders of the central and peripheral nervous system. J. Neuroimmunol. 40, 197-210.
16. Hirano, T., Akira, S., Taga, T. and Kishimoto, T. (1990) Biological and clinical aspects of interleukin-6. Immunol. Today 11, 443-449.
17. Jacobs, R.F. and Tabor, D.R. (1990) The immunology of sepsis and meningitis-cytokine biology. Scand. J. Infect. Dis. (Suppl.) 73, 7-15.
18. 2 receptors on human endothelial cells. Circulation Res. 72, 958-965.
19. Kirn, K.S., Wass, C.A., Cross, A.S. and Opal, S.M. (1992) Modulation of blood-brain barrier permeability by tumor necrosis factor-α in the rat. Lymphokine Cytokine Res. 11, 293-298.
20. Kluger, M.J. (1991) Fever: role of pyrogens and cryogens. Physiol. Rev. 71, 93-127.
21. Liuzzi, G.M., Mastroianni, C.M., Vullo, V., Jirillo, E., Delia, S. and Riccio, P. (1992) Cerebrospinal fluid myelin basic protein as predictive marker of demyelination in AIDS dementia complex. J. Neuroimmunol. 36, 251-254.
22. Matsuda, M., Tsukada, N., Iyagi, K. and Yanagisawa, N. (1991) Increased interleukin-1 production by peripheral blood mononuclear cells in patients with multiple sclerosis. J. Neurol. Sci. 102, 100-104.
23. McCarthy, K.D. and De Vellis, J. (1980) Preparation of separate as-troglial and oligodendroglial cultures from rat cerebral tissue. J. Cell Biol. 85, 890-902.
24. Megyeri, P., Abraham, C.S., Temesvari, P., Kovacs, J., Vas, T. and Speer, C.P. (1992) Recombinant human tumor necrosis factor α constricts pial arterioles and increases blood-brain barrier permeability in newborn piglets. Neurosci. Lett. 148, 137-140.
25. Moor, A.C.E., de Vries, H.E., De Boer, A.G. and Breimer, D.D. (1994) The blood-brain barrier and multiple sclerosis. Biochem. Pharmacol. 47, 1717-1724.
26. Morganti-Kossmann, M.C., Kossmann, T. and Wahl, S.M. (1992) Cytokines and neuropathology. Trends Pharmacol. Sci. 13, 286-291.
27. Quagliarello, V.J., Long, W.J. and Scheid, W.M. (1986) Morphological alterations of the blood-brain barrier with experimental meningitis in the rat. J. Clin. Invest. 77, 1084-1095.
28. Plata-Salamán, C.R. (1991) Immunoregulators in the nervous system. Neurosci. Biobehav. Rev. 15, 185-215.
29. Plata-Salamán, C.R. and Borkoski, J.P. (1994) Chemokines/intercrines and central regulation of feeding. Am. J. Physiol. 265, R1711-R1715.
30. Rothwell, N.J. (1991) Functions and mechanisms of interleukin 1 in the brain. Trends Pharmacol. Sci. 12, 430-436.
31. Rott, O., Tontsch, U., Fleischer, B. and Cash, E. (1993) Interleukin-6 production in normal and HTLV-1 tax-expressing brain specific endothelial cells. Eur. J. Immunol. 23, 1987-1991.