Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain

EMBO Reports

Volumn 4, Issue 8, 2003, Pages 787-792

  Craig, Ashley ^a   Scott, Mary ^a   Burch, Lindsay ^a   Smith, Graeme ^b   Ball, Kathryn ^a   Hupp, Ted ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b KuDOS Pharmaceuticals Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CHECKPOINT KINASE 2; DNA; DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN; PROTEIN KINASE; PROTEIN P21; PROTEIN P53; PROTEIN SERINE KINASE; SERINE; THREONINE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING SITE; CELL DIVISION; CONTROLLED STUDY; DATA BASE; DNA BINDING; DNA DAMAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; GENE MUTATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ALLOSTERIC REGULATION; AMINO ACID MOTIFS; BINDING SITES; CELL CYCLE PROTEINS; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; HUMANS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53;

EID: 0042854721     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.embor901     Document Type: Article

References (17)

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