메뉴 건너뛰기




Volumn 8, Issue , 2020, Pages

Advantages and Limitations of the Neonatal Immune System

Author keywords

brain injury; infections; innate immunity; neonates; neurodevelopment; sepsis

Indexed keywords

ANTIGEN PRESENTING CELL; EPIGENETICS; GRANULOCYTE; HUMAN; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; INFECTION; INNATE IMMUNITY; LYMPHOID CELL; METABOLOME; MICROBIOME; NATURAL KILLER CELL; NERVE CELL DIFFERENTIATION; NEWBORN; PHAGOCYTE; REVIEW; SEPSIS; TISSUE INJURY;

EID: 85079507542     PISSN: None     EISSN: 22962360     Source Type: Journal    
DOI: 10.3389/fped.2020.00005     Document Type: Review
Times cited : (91)

References (107)
  • 1
    • 84931078846 scopus 로고    scopus 로고
    • Transition from fetus to newborn
    • 25836701
    • Swanson JR, Sinkin RA. Transition from fetus to newborn. Pediatr Clin North Am. (2015) 62:329–43. 10.1016/j.pcl.2014.11.00225836701
    • (2015) Pediatr Clin North Am , vol.62 , pp. 329-343
    • Swanson, J.R.1    Sinkin, R.A.2
  • 2
    • 84866272420 scopus 로고    scopus 로고
    • The role of cytokines and inflammatory cells in perinatal brain injury
    • 22530124
    • McAdams RM, Juul SE. The role of cytokines and inflammatory cells in perinatal brain injury. Neurol Res Int. (2012) 2012:561494. 10.1155/2012/56149422530124
    • (2012) Neurol Res Int , vol.2012 , pp. 561494
    • McAdams, R.M.1    Juul, S.E.2
  • 3
    • 41149144222 scopus 로고    scopus 로고
    • Antenatal risk factors for postnatal depression: a large prospective study
    • 18067974
    • Milgrom J, Gemmill AW, Bilszta JL, Hayes B, Barnett B, Brooks J, et al. Antenatal risk factors for postnatal depression: a large prospective study. J Affect Disord. (2008) 108:147–57. 10.1016/j.jad.2007.10.01418067974
    • (2008) J Affect Disord , vol.108 , pp. 147-157
    • Milgrom, J.1    Gemmill, A.W.2    Bilszta, J.L.3    Hayes, B.4    Barnett, B.5    Brooks, J.6
  • 5
    • 77953522678 scopus 로고    scopus 로고
    • Role of innate host defenses in susceptibility to early-onset neonatal sepsis
    • 20569810
    • Wynn JL, Levy O. Role of innate host defenses in susceptibility to early-onset neonatal sepsis. Clin Perinatol. (2010) 37:307–37. 10.1016/j.clp.2010.04.00120569810
    • (2010) Clin Perinatol , vol.37 , pp. 307-337
    • Wynn, J.L.1    Levy, O.2
  • 6
    • 84981736021 scopus 로고    scopus 로고
    • Fetal physiology and the transition to extrauterine life
    • 27524443
    • Morton SU, Brodsky D. Fetal physiology and the transition to extrauterine life. Clin Perinatol. (2016) 43:395–407. 10.1016/j.clp.2016.04.00127524443
    • (2016) Clin Perinatol , vol.43 , pp. 395-407
    • Morton, S.U.1    Brodsky, D.2
  • 7
    • 34250159927 scopus 로고    scopus 로고
    • Development of dendritic-cell lineages
    • 17582346
    • Wu L, Liu YJ. Development of dendritic-cell lineages. Immunity. (2007) 26:741–50. 10.1016/j.immuni.2007.06.00617582346
    • (2007) Immunity , vol.26 , pp. 741-750
    • Wu, L.1    Liu, Y.J.2
  • 8
    • 0036242980 scopus 로고    scopus 로고
    • Neonatal dendritic cells are intrinsically biased against Th-1 immune responses
    • 11982599
    • Langrish CL, Buddle JC, Thrasher AJ, Goldblatt D. Neonatal dendritic cells are intrinsically biased against Th-1 immune responses. Clin Exp Immunol. (2002) 128:118–23. 10.1046/j.1365-2249.2002.01817.x11982599
    • (2002) Clin Exp Immunol , vol.128 , pp. 118-123
    • Langrish, C.L.1    Buddle, J.C.2    Thrasher, A.J.3    Goldblatt, D.4
  • 9
    • 60549089619 scopus 로고    scopus 로고
    • Phenotype and function of neonatal DC
    • 19137537
    • Willems F, Vollstedt S, Suter M. Phenotype and function of neonatal DC. Eur J Immunol. (2009) 39:26–35. 10.1002/eji.20083839119137537
    • (2009) Eur J Immunol , vol.39 , pp. 26-35
    • Willems, F.1    Vollstedt, S.2    Suter, M.3
  • 10
    • 0035313447 scopus 로고    scopus 로고
    • Regulatory activity of autocrine IL-10 on dendritic cell functions
    • 11254683
    • Corinti S, Albanesi C, la Sala A, Pastore S, Girolomoni G. Regulatory activity of autocrine IL-10 on dendritic cell functions. J Immunol. (2001) 166:4312–8. 10.4049/jimmunol.166.7.431211254683
    • (2001) J Immunol , vol.166 , pp. 4312-4318
    • Corinti, S.1    Albanesi, C.2    la Sala, A.3    Pastore, S.4    Girolomoni, G.5
  • 11
    • 0028067831 scopus 로고
    • Studies of human cord blood dendritic cells: evidence for functional immaturity
    • 7994049
    • Hunt DWC, Huppertz HI, Jiang HJ, Petty RE. Studies of human cord blood dendritic cells: evidence for functional immaturity. Blood. (1994) 84:4333–43. 10.1182/blood.V84.12.4333.bloodjournal841243337994049
    • (1994) Blood , vol.84 , pp. 4333-4343
    • Hunt, D.W.C.1    Huppertz, H.I.2    Jiang, H.J.3    Petty, R.E.4
  • 12
    • 85060588470 scopus 로고    scopus 로고
    • Understanding the functional properties of neonatal dendritic cells : a doorway to enhance vaccine effectiveness?
    • 30687326
    • Papaioannou NE, Pasztoi M, Schraml BU. Understanding the functional properties of neonatal dendritic cells: a doorway to enhance vaccine effectiveness? Front immunol. (2019) 9:3123. 10.3389/fimmu.2018.0312330687326
    • (2019) Front immunol , vol.9 , pp. 3123
    • Papaioannou, N.E.1    Pasztoi, M.2    Schraml, B.U.3
  • 13
    • 1642581673 scopus 로고    scopus 로고
    • Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns
    • 14504106
    • De Wit D, Olislagers V, Goriely S, Vermeulen F, Wagner H, Goldman M, et al. Blood plasmacytoid dendritic cell responses to CpG oligodeoxynucleotides are impaired in human newborns. Blood. (2004) 103:1030–2. 10.1182/blood-2003-04-121614504106
    • (2004) Blood , vol.103 , pp. 1030-1032
    • De Wit, D.1    Olislagers, V.2    Goriely, S.3    Vermeulen, F.4    Wagner, H.5    Goldman, M.6
  • 14
    • 85026352032 scopus 로고    scopus 로고
    • Unique aspects of the perinatal
    • 28627520
    • Zhang X, Zhivaki D, Lo-man R. Unique aspects of the perinatal. Nat Publ Gr. (2017) 17:495–507. 10.1038/nri.2017.5428627520
    • (2017) Nat Publ Gr , vol.17 , pp. 495-507
    • Zhang, X.1    Zhivaki, D.2    Lo-man, R.3
  • 15
    • 77956397972 scopus 로고    scopus 로고
    • Acquisition of adult-like TLR4 and TLR9 responses during the first year of life
    • 20442853
    • Nguyen M, Leuridan E, Zhang T, De Wit D, Willems F, van Damme P, et al. Acquisition of adult-like TLR4 and TLR9 responses during the first year of life. PLoS ONE. (2010) 5:e10407. 10.1371/journal.pone.001040720442853
    • (2010) PLoS ONE , vol.5 , pp. e10407
    • Nguyen, M.1    Leuridan, E.2    Zhang, T.3    De Wit, D.4    Willems, F.5    van Damme, P.6
  • 16
    • 0027315505 scopus 로고
    • Diversity in regulation of adhesion molecules (Mac-1 and L-selectin) in monocytes and neutrophils from neonates and adults
    • 7686738
    • Torok C, Lundahl J, Hed J, Lagercrantz H. Diversity in regulation of adhesion molecules (Mac-1 and L-selectin) in monocytes and neutrophils from neonates and adults. Arch Dis Child. (1993) 68:561–5. 10.1136/adc.68.5_Spec_No.5617686738
    • (1993) Arch Dis Child , vol.68 , pp. 561-565
    • Torok, C.1    Lundahl, J.2    Hed, J.3    Lagercrantz, H.4
  • 17
  • 18
    • 84925517597 scopus 로고    scopus 로고
    • An impaired inflammatory cytokine response to gram-negative LPS in human neonates is associated with the defective TLR-mediated signaling pathway
    • 25631527
    • Li YP, Yu SL, Huang ZJ, Huang J, Pan J, Feng X, et al. An impaired inflammatory cytokine response to gram-negative LPS in human neonates is associated with the defective TLR-mediated signaling pathway. J Clin Immunol. (2015) 35:218–26. 10.1007/s10875-015-0128-625631527
    • (2015) J Clin Immunol , vol.35 , pp. 218-226
    • Li, Y.P.1    Yu, S.L.2    Huang, Z.J.3    Huang, J.4    Pan, J.5    Feng, X.6
  • 19
    • 84921064072 scopus 로고    scopus 로고
    • Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes
    • 25311115
    • Sharma AA, Jen R, Kan B, Sharma A, Marchant E, Tang A, et al. Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes. Eur J Immunol. (2015) 45:238–49. 10.1002/eji.20144470725311115
    • (2015) Eur J Immunol , vol.45 , pp. 238-249
    • Sharma, A.A.1    Jen, R.2    Kan, B.3    Sharma, A.4    Marchant, E.5    Tang, A.6
  • 20
    • 84904668417 scopus 로고    scopus 로고
    • Neonatal monocytes express antiapoptotic pattern of Bcl-2 proteins and show diminished apoptosis upon infection with Escherichia coli
    • 24850312
    • Leiber A, Graf B, Spring B, Rudner J, Köstlin N, Orlikowsky TW, et al. Neonatal monocytes express antiapoptotic pattern of Bcl-2 proteins and show diminished apoptosis upon infection with Escherichia coli. Pediatr Res. (2014) 76:142–9. 10.1038/pr.2014.7424850312
    • (2014) Pediatr Res , vol.76 , pp. 142-149
    • Leiber, A.1    Graf, B.2    Spring, B.3    Rudner, J.4    Köstlin, N.5    Orlikowsky, T.W.6
  • 21
    • 84921027625 scopus 로고    scopus 로고
    • Distinct phenotypic features of neonatal murine macrophages
    • 25329762
    • Winterberg T, Vieten G, Meier T, Yu Y, Busse M, Hennig C, et al. Distinct phenotypic features of neonatal murine macrophages. Eur J Immunol. (2015) 45:214–24. 10.1002/eji.20144446825329762
    • (2015) Eur J Immunol , vol.45 , pp. 214-224
    • Winterberg, T.1    Vieten, G.2    Meier, T.3    Yu, Y.4    Busse, M.5    Hennig, C.6
  • 22
    • 33747161725 scopus 로고    scopus 로고
    • Innate immunity of the human newborn is polarized toward a high ratio of IL-6/TNF-α production in vitro and in vivo
    • 16864705
    • Angelone DF, Wessels MR, Coughlin M, Suter EE, Valentini P, Kalish LA, et al. Innate immunity of the human newborn is polarized toward a high ratio of IL-6/TNF-α production in vitro and in vivo. Pediatr Res. (2006) 60:205–9. 10.1203/01.pdr.0000228319.10481.ea16864705
    • (2006) Pediatr Res , vol.60 , pp. 205-209
    • Angelone, D.F.1    Wessels, M.R.2    Coughlin, M.3    Suter, E.E.4    Valentini, P.5    Kalish, L.A.6
  • 23
    • 0023802007 scopus 로고
    • Phagocytosis-associated functions in neonatal monocyte-derived macrophages
    • 2847109
    • Speer CP, Gahr M, Wieland M, Eber S. Phagocytosis-associated functions in neonatal monocyte-derived macrophages. Pediatr Res. (1988) 24:213–6. 10.1203/00006450-198808000-000152847109
    • (1988) Pediatr Res , vol.24 , pp. 213-216
    • Speer, C.P.1    Gahr, M.2    Wieland, M.3    Eber, S.4
  • 24
    • 0025869795 scopus 로고
    • Diminished lectin-, epidermal growth factor-, complement binding domain-cell adhesion molecule-1 on neonatal neutrophils underlies their impaired CD18-independent adhesion to endothelial cells in vitro
    • 1709192
    • Anderson DC, Abbassi O, Kishimoto TK, Koenig JM, McIntire L V, Smith CW. Diminished lectin-, epidermal growth factor-, complement binding domain-cell adhesion molecule-1 on neonatal neutrophils underlies their impaired CD18-independent adhesion to endothelial cells in vitro. J Immunol. (1991) 146:3372–9. 1709192
    • (1991) J Immunol , vol.146 , pp. 3372-3379
    • Anderson, D.C.1    Abbassi, O.2    Kishimoto, T.K.3    Koenig, J.M.4    McIntire, L.V.5    Smith, C.W.6
  • 26
    • 0035216141 scopus 로고    scopus 로고
    • Mechanisms underlying reduced responsiveness of neonatal neutrophils to distinct chemoattractants
    • 11739560
    • Weinberger B, Laskin DL, Mariano TM, Sunil VR, DeCoste CJ, Heck DE, et al. Mechanisms underlying reduced responsiveness of neonatal neutrophils to distinct chemoattractants. J Leukoc Biol. (2001) 70:969–76. 10.1189/jlb.70.6.96911739560
    • (2001) J Leukoc Biol , vol.70 , pp. 969-976
    • Weinberger, B.1    Laskin, D.L.2    Mariano, T.M.3    Sunil, V.R.4    DeCoste, C.J.5    Heck, D.E.6
  • 27
    • 0021227906 scopus 로고
    • Chemotactic peptide modulation of actin assembly and locomotion in neutrophils
    • 6232281, :, −
    • Howard TH, Meyer WH. Chemotactic peptide modulation of actin assembly and locomotion in neutrophils. J Cell Biol. (1984) 98:1265−71. 10.1083/jcb.98.4.12656232281
    • (1984) J Cell Biol , vol.98 , pp. 1265-1271
    • Howard, T.H.1    Meyer, W.H.2
  • 28
    • 0028140426 scopus 로고
    • Deficient total cell content of CR3 (CD11b) in neonatal neutrophils
    • 7906565
    • Abughali N, Berger M, Tosi MF. Deficient total cell content of CR3 (CD11b) in neonatal neutrophils. Blood. (1994) 83:1086–92. 10.1182/blood.V83.4.1086.10867906565
    • (1994) Blood , vol.83 , pp. 1086-1092
    • Abughali, N.1    Berger, M.2    Tosi, M.F.3
  • 29
    • 84904011922 scopus 로고    scopus 로고
    • Quantitative proteomics reveals differential biological processes in healthy neonatal cord neutrophils and adult neutrophils
    • 24782442
    • Zhu J, Zhang H, Guo T, Li W, Li H, Zhu Y, et al. Quantitative proteomics reveals differential biological processes in healthy neonatal cord neutrophils and adult neutrophils. Proteomics. (2014) 14:1688–97. 10.1002/pmic.20140000924782442
    • (2014) Proteomics , vol.14 , pp. 1688-1697
    • Zhu, J.1    Zhang, H.2    Guo, T.3    Li, W.4    Li, H.5    Zhu, Y.6
  • 30
    • 84936803219 scopus 로고    scopus 로고
    • Neonatal basophils stifle the function of early-life dendritic cells to curtail Th1 immunity in newborn mice
    • 26034171
    • Dhakal M, Miller MM, Zaghouani AA, Sherman MP, Zaghouani H. Neonatal basophils stifle the function of early-life dendritic cells to curtail Th1 immunity in newborn mice. J Immunol. (2015) 195:507–18. 10.4049/jimmunol.150002726034171
    • (2015) J Immunol , vol.195 , pp. 507-518
    • Dhakal, M.1    Miller, M.M.2    Zaghouani, A.A.3    Sherman, M.P.4    Zaghouani, H.5
  • 31
    • 79955099971 scopus 로고    scopus 로고
    • Natural killer cell responses to infections in early life
    • 21411972
    • Guilmot A, Hermann E, Braud VM, Carlier Y, Truyens C. Natural killer cell responses to infections in early life. J Innate Immun. (2011) 3:280–8. 10.1159/00032393421411972
    • (2011) J Innate Immun , vol.3 , pp. 280-288
    • Guilmot, A.1    Hermann, E.2    Braud, V.M.3    Carlier, Y.4    Truyens, C.5
  • 32
    • 77957803871 scopus 로고    scopus 로고
    • Human NK cells display major phenotypic and functional changes over the life span
    • Le Garff-Tavernier M, Béziat V, Decocq J, Siguret V, Gandjbakhch F, Pautas E, et al. Human NK cells display major phenotypic and functional changes over the life span. Aging Cell. (2010) 9:527–35. 10.1111/j.1474-9726.2010.00584.x
    • (2010) Aging Cell , vol.9 , pp. 527-535
    • Le, G.-T.M.1    Béziat, V.2    Decocq, J.3    Siguret, V.4    Gandjbakhch, F.5    Pautas, E.6
  • 33
    • 0033854779 scopus 로고    scopus 로고
    • Intracellular cytokine profile of cord blood T-, and NK- cells and monocytes
    • 10897117
    • Krampera M, Tavecchia L, Benedetti F, Nadali G, Pizzolo G. Intracellular cytokine profile of cord blood T-, and NK- cells and monocytes. Haematologica. (2000) 85:675–9. 10897117
    • (2000) Haematologica , vol.85 , pp. 675-679
    • Krampera, M.1    Tavecchia, L.2    Benedetti, F.3    Nadali, G.4    Pizzolo, G.5
  • 34
    • 0032703698 scopus 로고    scopus 로고
    • Adhesion defects of antibody-mediated target cell binding of neonatal natural killer cells
    • 10590035
    • Kohl S, Sigouroudinia M, Engleman EG. Adhesion defects of antibody-mediated target cell binding of neonatal natural killer cells. Pediatr Res. (1999) 46:755. 10.1203/00006450-199912000-0001810590035
    • (1999) Pediatr Res , vol.46 , pp. 755
    • Kohl, S.1    Sigouroudinia, M.2    Engleman, E.G.3
  • 37
    • 84974829834 scopus 로고    scopus 로고
    • Cutting edge: innate lymphoid cells suppress homeostatic T cell expansion in neonatal mice
    • 26983785
    • Bank U, Deiser K, Finke D, Hämmerling GJ, Arnold B, Schüler T. Cutting edge: innate lymphoid cells suppress homeostatic T cell expansion in neonatal mice. J Immunol. (2016) 196:3532–6. 10.4049/jimmunol.150164326983785
    • (2016) J Immunol , vol.196 , pp. 3532-3536
    • Bank, U.1    Deiser, K.2    Finke, D.3    Hämmerling, G.J.4    Arnold, B.5    Schüler, T.6
  • 38
    • 85048682423 scopus 로고    scopus 로고
    • Presence and profile of innate lymphoid cells in human breast milk
    • 29630693
    • Baban B, Malik A, Bhatia J, Yu JC. Presence and profile of innate lymphoid cells in human breast milk. JAMA Pediatr. (2018) 172:594–6. 10.1001/jamapediatrics.2018.014829630693
    • (2018) JAMA Pediatr , vol.172 , pp. 594-596
    • Baban, B.1    Malik, A.2    Bhatia, J.3    Yu, J.C.4
  • 40
    • 85028657679 scopus 로고    scopus 로고
    • The phenotype and function of preterm infant monocytes: implications for susceptibility to infection
    • 28630102
    • de Jong E, Strunk T, Burgner D, Lavoie PM, Currie A. The phenotype and function of preterm infant monocytes: implications for susceptibility to infection. J Leukoc Biol. (2017) 102:645–56. 10.1189/jlb.4RU0317-111R28630102
    • (2017) J Leukoc Biol , vol.102 , pp. 645-656
    • de Jong, E.1    Strunk, T.2    Burgner, D.3    Lavoie, P.M.4    Currie, A.5
  • 41
    • 85037824673 scopus 로고    scopus 로고
    • Early microbes modify immune system development and metabolic homeostasis-the “Restaurant” hypothesis revisited
    • 29326657
    • Nash MJ, Frank DN, Friedman JE. Early microbes modify immune system development and metabolic homeostasis-the “Restaurant” hypothesis revisited. Front Endocrinol. (2017) 8:349. 10.3389/fendo.2017.0034929326657
    • (2017) Front Endocrinol , vol.8 , pp. 349
    • Nash, M.J.1    Frank, D.N.2    Friedman, J.E.3
  • 42
    • 0037087421 scopus 로고    scopus 로고
    • Differential patterns of methylation of the IFN-gamma promoter at CpG and Non-CpG Sites underlie differences in IFN-gamma Gene expression between human neonatal and adult CD45RO- T Cells
    • 11884451
    • White GP, Watt PM, Holt BJ, Holt PG. Differential patterns of methylation of the IFN-gamma promoter at CpG and Non-CpG Sites underlie differences in IFN-gamma Gene expression between human neonatal and adult CD45RO- T Cells. J Immunol. (2002) 168:2820–7. 10.4049/jimmunol.168.6.282011884451
    • (2002) J Immunol , vol.168 , pp. 2820-2827
    • White, G.P.1    Watt, P.M.2    Holt, B.J.3    Holt, P.G.4
  • 43
    • 84874110756 scopus 로고    scopus 로고
    • Role of innate immunity in neonatal infection
    • 23297181
    • Cuenca AG, Wynn JL, Moldawer LL, Levy O. Role of innate immunity in neonatal infection. Am J Perinatol. (2013) 30:105–12. 10.1055/s-0032-133341223297181
    • (2013) Am J Perinatol , vol.30 , pp. 105-112
    • Cuenca, A.G.1    Wynn, J.L.2    Moldawer, L.L.3    Levy, O.4
  • 44
  • 45
    • 85017323651 scopus 로고    scopus 로고
    • Correlation between early-life regulation of the immune system by microbiota and allergy development
    • 28390575
    • Gensollen T, Blumberg RS. Correlation between early-life regulation of the immune system by microbiota and allergy development. J Allergy Clin Immunol. (2017) 139:1084–91. 10.1016/j.jaci.2017.02.01128390575
    • (2017) J Allergy Clin Immunol , vol.139 , pp. 1084-1091
    • Gensollen, T.1    Blumberg, R.S.2
  • 46
    • 84965002935 scopus 로고    scopus 로고
    • How colonization by microbiota in early life shapes the immune system
    • 27126036
    • Gensollen T, Iyer SS, Kasper DL, Blumberg RS, Medical H. How colonization by microbiota in early life shapes the immune system. Science. (2016) 352:539–44. 10.1126/science.aad937827126036
    • (2016) Science , vol.352 , pp. 539-544
    • Gensollen, T.1    Iyer, S.S.2    Kasper, D.L.3    Blumberg, R.S.4    Medical, H.5
  • 47
    • 84978115999 scopus 로고    scopus 로고
    • The microbiome and innate immunity
    • 27383981
    • Thaiss CA, Zmora N, Levy M, Elinav E. The microbiome and innate immunity. Nature. (2016) 535:65–74. 10.1038/nature1884727383981
    • (2016) Nature , vol.535 , pp. 65-74
    • Thaiss, C.A.1    Zmora, N.2    Levy, M.3    Elinav, E.4
  • 48
    • 85015771024 scopus 로고    scopus 로고
    • Protecting the newborn and young infant from infectious diseases: lessons from immune ontogeny
    • 28329702
    • Kollmann TR, Kampmann B, Mazmanian SK, Marchant A, Levy O. Protecting the newborn and young infant from infectious diseases: lessons from immune ontogeny. Immunity. (2017) 46:350–63. 10.1016/j.immuni.2017.03.00928329702
    • (2017) Immunity , vol.46 , pp. 350-363
    • Kollmann, T.R.1    Kampmann, B.2    Mazmanian, S.K.3    Marchant, A.4    Levy, O.5
  • 49
    • 84955313171 scopus 로고    scopus 로고
    • Metabolomics in newborns
    • 27117660
    • Noto A, Fanos V, Dessì A. Metabolomics in newborns. Adv Clin Chem. (2016) 74:35–61. 10.1016/bs.acc.2015.12.00627117660
    • (2016) Adv Clin Chem , vol.74 , pp. 35-61
    • Noto, A.1    Fanos, V.2    Dessì, A.3
  • 50
    • 84975755277 scopus 로고    scopus 로고
    • Exploring the role of different neonatal nutrition regimens during the first week of life by urinary GC-MS metabolomics
    • 26907266
    • Dessi A, Murgia A, Agostino R, Pattumelli MG, Schirru A, Scano P, et al. Exploring the role of different neonatal nutrition regimens during the first week of life by urinary GC-MS metabolomics. Int J Mol Sci. (2016) 17:265. 10.3390/ijms1702026526907266
    • (2016) Int J Mol Sci , vol.17 , pp. 265
    • Dessi, A.1    Murgia, A.2    Agostino, R.3    Pattumelli, M.G.4    Schirru, A.5    Scano, P.6
  • 51
    • 84883781183 scopus 로고    scopus 로고
    • 1H NMR derived metabolomic profile of neonatal asphyxia in umbilical cord serum: implications for hypoxic ischemic encephalopathy
    • 23931672
    • Reinke SN, Walsh BH, Boylan GB, Sykes BD, Kenny LC, Murray DM, et al. 1H NMR derived metabolomic profile of neonatal asphyxia in umbilical cord serum: implications for hypoxic ischemic encephalopathy. J Proteome Res. (2013) 12:4230–9. 10.1021/pr400617m23931672
    • (2013) J Proteome Res , vol.12 , pp. 4230-4239
    • Reinke, S.N.1    Walsh, B.H.2    Boylan, G.B.3    Sykes, B.D.4    Kenny, L.C.5    Murray, D.M.6
  • 52
    • 84925012895 scopus 로고    scopus 로고
    • Betaine supplementation prevents fatty liver induced by a high-fat diet: effects on one-carbon metabolism
    • 25577261
    • Deminice R, da Silva RP, Lamarre SG, Kelly KB, Jacobs RL, Brosnan ME, et al. Betaine supplementation prevents fatty liver induced by a high-fat diet: effects on one-carbon metabolism. Amino Acids. (2015) 47:839–46. 10.1007/s00726-014-1913-x25577261
    • (2015) Amino Acids , vol.47 , pp. 839-846
    • Deminice, R.1    da Silva, R.P.2    Lamarre, S.G.3    Kelly, K.B.4    Jacobs, R.L.5    Brosnan, M.E.6
  • 53
    • 84897529055 scopus 로고    scopus 로고
    • Urinary (1)H-NMR and GC-MS metabolomics predicts early and late onset neonatal sepsis
    • 24709468
    • Fanos V, Caboni P, Corsello G, Stronati M, Gazzolo D, Noto A, et al. Urinary (1)H-NMR and GC-MS metabolomics predicts early and late onset neonatal sepsis. Early Hum Dev. (2014) 90(Suppl. 1):S78–83. 10.1016/S0378-3782(14)70024-624709468
    • (2014) Early Hum Dev , vol.90 , pp. S78-S83
    • Fanos, V.1    Caboni, P.2    Corsello, G.3    Stronati, M.4    Gazzolo, D.5    Noto, A.6
  • 55
    • 84949255712 scopus 로고    scopus 로고
    • Metabolomic Quantitative Trait Loci (mQTL) mapping implicates the ubiquitin proteasome system in cardiovascular disease pathogenesis
    • 26540294
    • Kraus WE, Muoio DM, Stevens R, Craig D, Bain JR, Grass E, et al. Metabolomic Quantitative Trait Loci (mQTL) mapping implicates the ubiquitin proteasome system in cardiovascular disease pathogenesis. PLoS Genet. (2015) 11:e1005553. 10.1371/journal.pgen.100555326540294
    • (2015) PLoS Genet , vol.11 , pp. e1005553
    • Kraus, W.E.1    Muoio, D.M.2    Stevens, R.3    Craig, D.4    Bain, J.R.5    Grass, E.6
  • 56
    • 84881068658 scopus 로고    scopus 로고
    • The microbial metabolites, short-chain fatty acids, regulate colonic treg cell homeostasis
    • 23828891
    • Smith PM, Howitt MR, Panikov N, Michaud M, Gallini CA, Bohlooly YM, et al. The microbial metabolites, short-chain fatty acids, regulate colonic treg cell homeostasis. Science. (2013) 341:569–73. 10.1126/science.124116523828891
    • (2013) Science , vol.341 , pp. 569-573
    • Smith, P.M.1    Howitt, M.R.2    Panikov, N.3    Michaud, M.4    Gallini, C.A.5    Bohlooly, Y.M.6
  • 57
    • 84959016595 scopus 로고    scopus 로고
    • Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children
    • 26912898
    • Blanton LV, Charbonneau MR, Salih T, Barratt MJ, Venkatesh S, Ilkaveya O, et al. Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children. Science. (2016) 351:aad3311. 10.1126/science.aad331126912898
    • (2016) Science , vol.351 , pp. aad3311
    • Blanton, L.V.1    Charbonneau, M.R.2    Salih, T.3    Barratt, M.J.4    Venkatesh, S.5    Ilkaveya, O.6
  • 58
    • 84878579044 scopus 로고    scopus 로고
    • The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43
    • 23652017
    • Kimura I, Ozawa K, Inoue D, Imamura T, Kimura K, Maeda T, et al. The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43. Nat Commun. (2013) 4:1829. 10.1038/ncomms285223652017
    • (2013) Nat Commun , vol.4 , pp. 1829
    • Kimura, I.1    Ozawa, K.2    Inoue, D.3    Imamura, T.4    Kimura, K.5    Maeda, T.6
  • 59
    • 85020377518 scopus 로고    scopus 로고
    • Temporal bacterial and metabolic development of the preterm gut reveals specific signatures in health and disease
    • 28034304
    • Stewart CJ, Embleton ND, Marrs ECL, Smith DP, Nelson A, Abdulkadir B, et al. Temporal bacterial and metabolic development of the preterm gut reveals specific signatures in health and disease. Microbiome. (2016) 4:67. 10.1186/s40168-016-0216-828034304
    • (2016) Microbiome , vol.4 , pp. 67
    • Stewart, C.J.1    Embleton, N.D.2    Marrs, E.C.L.3    Smith, D.P.4    Nelson, A.5    Abdulkadir, B.6
  • 60
    • 76949122636 scopus 로고
    • Glucose and gluconic acid oxidation of Pseudomonas saccharophila
    • 12981024
    • Entner N, Doudoroff M. Glucose and gluconic acid oxidation of Pseudomonas saccharophila. J Biol Chem. (1952) 196:853–62. 12981024
    • (1952) J Biol Chem , vol.196 , pp. 853-862
    • Entner, N.1    Doudoroff, M.2
  • 63
    • 33644616250 scopus 로고    scopus 로고
    • Seventy-five years of neonatal sepsis at Yale: 1928-2003
    • 16140698
    • Bizzarro MJ, Raskind C, Baltimore RS, Gallagher PG. Seventy-five years of neonatal sepsis at Yale: 1928-2003. Pediatrics. (2005) 116:595–602. 10.1542/peds.2005-055216140698
    • (2005) Pediatrics , vol.116 , pp. 595-602
    • Bizzarro, M.J.1    Raskind, C.2    Baltimore, R.S.3    Gallagher, P.G.4
  • 64
    • 70349286781 scopus 로고    scopus 로고
    • Inflammatory and oxidative parameters in cord blood as diagnostic of early-onset neonatal sepsis: a case-control study
    • 19307820
    • Cancelier AC, Petronilho F, Reinke A, Constantino L, Machado R, Ritter C, et al. Inflammatory and oxidative parameters in cord blood as diagnostic of early-onset neonatal sepsis: a case-control study. Pediatr Crit Care Med. (2009) 10:467–71. 10.1097/PCC.0b013e318198b0e319307820
    • (2009) Pediatr Crit Care Med , vol.10 , pp. 467-471
    • Cancelier, A.C.1    Petronilho, F.2    Reinke, A.3    Constantino, L.4    Machado, R.5    Ritter, C.6
  • 65
  • 66
    • 0343384376 scopus 로고    scopus 로고
    • The analysis of the complement activation product SC5 b-9 is applicable in neonates in spite of their profound C9 deficiency
    • 10765513
    • Hogasen AK, Overlie I, Hansen TW, Abrahamsen TG, Finne PH, Hogasen K. The analysis of the complement activation product SC5 b-9 is applicable in neonates in spite of their profound C9 deficiency. J Perinat Med. (2000) 28:39–48. 10.1515/JPM.2000.00610765513
    • (2000) J Perinat Med , vol.28 , pp. 39-48
    • Hogasen, A.K.1    Overlie, I.2    Hansen, T.W.3    Abrahamsen, T.G.4    Finne, P.H.5    Hogasen, K.6
  • 67
    • 0034012481 scopus 로고    scopus 로고
    • Diminished inducible nitric oxide synthase expression in fulminant early-onset neonatal pneumonia
    • 10790456
    • Aikio O, Vuopala K, Pokela ML, Hallman M. Diminished inducible nitric oxide synthase expression in fulminant early-onset neonatal pneumonia. Pediatrics. (2000) 105:1013–9. 10.1542/peds.105.5.101310790456
    • (2000) Pediatrics , vol.105 , pp. 1013-1019
    • Aikio, O.1    Vuopala, K.2    Pokela, M.L.3    Hallman, M.4
  • 68
    • 67650638848 scopus 로고    scopus 로고
    • Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates
    • 19221037
    • Yost CC, Cody MJ, Harris ES, Thornton NL, McInturff AM, Martinez ML, et al. Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates. Blood. (2009) 113:6419–27. 10.1182/blood-2008-07-17162919221037
    • (2009) Blood , vol.113 , pp. 6419-6427
    • Yost, C.C.1    Cody, M.J.2    Harris, E.S.3    Thornton, N.L.4    McInturff, A.M.5    Martinez, M.L.6
  • 69
    • 0034941980 scopus 로고    scopus 로고
    • Natural killer cell cytotoxicity is deficient in newborns with sepsis and recurrent infections
    • 11548185
    • Georgeson GD, Szony BJ, Streitman K, Kovács A, Kovács L, László A. Natural killer cell cytotoxicity is deficient in newborns with sepsis and recurrent infections. Eur J Pediatr. (2001) 160:478–82. 10.1007/s00431010077311548185
    • (2001) Eur J Pediatr , vol.160 , pp. 478-482
    • Georgeson, G.D.1    Szony, B.J.2    Streitman, K.3    Kovács, A.4    Kovács, L.5    László, A.6
  • 70
    • 85011965804 scopus 로고    scopus 로고
    • Neonatal sepsis and neurodevelopment in very low birth weight infants in Matanzas, Cuba 2006-2010: a prospective cohort study
    • 27097362
    • Robaina Castellanos GR, Riesgo Rodriguez S, de la C. Neonatal sepsis and neurodevelopment in very low birth weight infants in Matanzas, Cuba 2006-2010: a prospective cohort study. Medwave. (2016) 16:e6422. 10.5867/medwave.2016.02.642227097362
    • (2016) Medwave , vol.16 , pp. e6422
    • Robaina Castellanos, G.R.1    Riesgo Rodriguez, S.2    de la, C.3
  • 72
    • 2342562427 scopus 로고    scopus 로고
    • Diagnostic markers of infection in neonates
    • 15102726
    • Ng PC. Diagnostic markers of infection in neonates. Arch Dis Child Fetal Neonatal Ed. (2004) 89:F229-35. 10.1136/adc.2002.02383815102726
    • (2004) Arch Dis Child Fetal Neonatal Ed , vol.89 , pp. F229-F235
    • Ng, P.C.1
  • 74
    • 77956168341 scopus 로고    scopus 로고
    • Biomarkers for late-onset neonatal sepsis: cytokines and beyond
    • 20813273
    • Ng PC, Lam HS. Biomarkers for late-onset neonatal sepsis: cytokines and beyond. Clin Perinatol. (2010) 37:599–610. 10.1016/j.clp.2010.05.00520813273
    • (2010) Clin Perinatol , vol.37 , pp. 599-610
    • Ng, P.C.1    Lam, H.S.2
  • 75
    • 0029022335 scopus 로고
    • Inflammatory mediators and neonatal sepsis. rarely has so little been known by so many about so much
    • 7671549
    • Meadow W, Rudinsky B. Inflammatory mediators and neonatal sepsis. rarely has so little been known by so many about so much. Clin Perinatol. (1995) 22:519–36. 10.1016/S0095-5108(18)30295-17671549
    • (1995) Clin Perinatol , vol.22 , pp. 519-536
    • Meadow, W.1    Rudinsky, B.2
  • 76
    • 85056530846 scopus 로고    scopus 로고
    • Clinical chorioamnionitis at term IX: in vivo evidence of intra-amniotic inflammasome activation
    • 30412466
    • Gomez-Lopez N, Romero R, Maymon E, Kusanovic JP, Panaitescu B, Miller D, et al. Clinical chorioamnionitis at term IX: in vivo evidence of intra-amniotic inflammasome activation. J Perinat Med. (2019) 47:276–87. 10.1515/jpm-2018-027130412466
    • (2019) J Perinat Med , vol.47 , pp. 276-287
    • Gomez-Lopez, N.1    Romero, R.2    Maymon, E.3    Kusanovic, J.P.4    Panaitescu, B.5    Miller, D.6
  • 77
    • 84942586832 scopus 로고    scopus 로고
    • Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance
    • 26428501
    • Kim CJ, Romero R, Chaemsaithong P, Chaiyasit N, Yoon BH, Kim YM. Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance. Am J Obstet Gynecol. (2015) 213:S29–52. 10.1016/j.ajog.2015.08.04026428501
    • (2015) Am J Obstet Gynecol , vol.213 , pp. S29-S52
    • Kim, C.J.1    Romero, R.2    Chaemsaithong, P.3    Chaiyasit, N.4    Yoon, B.H.5    Kim, Y.M.6
  • 79
    • 70349794451 scopus 로고    scopus 로고
    • Immune proteins in brain development and synaptic plasticity
    • 19840552
    • Boulanger LM. Immune proteins in brain development and synaptic plasticity. Neuron. (2009) 64:93–109. 10.1016/j.neuron.2009.09.00119840552
    • (2009) Neuron , vol.64 , pp. 93-109
    • Boulanger, L.M.1
  • 80
    • 70349813944 scopus 로고    scopus 로고
    • Immune influence on adult neural stem cell regulation and function
    • 19840551
    • Carpentier PA, Palmer TD. Immune influence on adult neural stem cell regulation and function. Neuron. (2009) 64:79–92. 10.1016/j.neuron.2009.08.03819840551
    • (2009) Neuron , vol.64 , pp. 79-92
    • Carpentier, P.A.1    Palmer, T.D.2
  • 81
    • 84981736300 scopus 로고    scopus 로고
    • Pathophysiology of Birth Asphyxia
    • 27524444
    • Rainaldi MA, Perlman JM. Pathophysiology of Birth Asphyxia. Clin Perinatol. (2016) 43:409–22. 10.1016/j.clp.2016.04.00227524444
    • (2016) Clin Perinatol , vol.43 , pp. 409-422
    • Rainaldi, M.A.1    Perlman, J.M.2
  • 83
    • 33644643210 scopus 로고    scopus 로고
    • IL-1beta, IL-6 and TNF-alpha and outcomes of neonatal hypoxic ischemic encephalopathy
    • 16181755
    • Aly H, Khashaba MT, El-Ayouty M, El-Sayed O, Hasanein BM. IL-1beta, IL-6 and TNF-alpha and outcomes of neonatal hypoxic ischemic encephalopathy. Brain Dev. (2006) 28:178–82. 10.1016/j.braindev.2005.06.00616181755
    • (2006) Brain Dev , vol.28 , pp. 178-182
    • Aly, H.1    Khashaba, M.T.2    El-Ayouty, M.3    El-Sayed, O.4    Hasanein, B.M.5
  • 84
    • 0345816795 scopus 로고    scopus 로고
    • Umbilical cord interleukin-6 levels are elevated in term neonates with perinatal asphyxia
    • 12662167
    • Chiesa C, Pellegrini G, Panero A, De Luca T, Assumma M, Signore F, et al. Umbilical cord interleukin-6 levels are elevated in term neonates with perinatal asphyxia. Eur J Clin Invest. (2003) 33:352–8. 10.1046/j.1365-2362.2003.01136.x12662167
    • (2003) Eur J Clin Invest , vol.33 , pp. 352-358
    • Chiesa, C.1    Pellegrini, G.2    Panero, A.3    De Luca, T.4    Assumma, M.5    Signore, F.6
  • 85
    • 0344222205 scopus 로고    scopus 로고
    • Cytokine response in cerebrospinal fluid after birth asphyxia
    • 9621983
    • Savman K, Blennow M, Gustafson K, Tarkowski E, Hagberg H. Cytokine response in cerebrospinal fluid after birth asphyxia. Pediatr Res. (1998) 43:746–51. 10.1203/00006450-199806000-000069621983
    • (1998) Pediatr Res , vol.43 , pp. 746-751
    • Savman, K.1    Blennow, M.2    Gustafson, K.3    Tarkowski, E.4    Hagberg, H.5
  • 86
    • 33645556225 scopus 로고    scopus 로고
    • Elevation of cytokine concentrations in asphyxiated neonates
    • 16244469
    • Okazaki K, Nishida A, Kato M, Kozawa K, Uga N, Kimura H. Elevation of cytokine concentrations in asphyxiated neonates. Biol Neonate. (2006) 89:183–9. 10.1159/00008918016244469
    • (2006) Biol Neonate , vol.89 , pp. 183-189
    • Okazaki, K.1    Nishida, A.2    Kato, M.3    Kozawa, K.4    Uga, N.5    Kimura, H.6
  • 87
    • 34249856663 scopus 로고    scopus 로고
    • Elevated total peripheral leukocyte count may identify risk for neurological disability in asphyxiated term neonates
    • 17443199
    • Morkos AA, Hopper AO, Deming DD, Yellon SM, Wycliffe N, Ashwal S, et al. Elevated total peripheral leukocyte count may identify risk for neurological disability in asphyxiated term neonates. J Perinatol. (2007) 27:365–70. 10.1038/sj.jp.721175017443199
    • (2007) J Perinatol , vol.27 , pp. 365-370
    • Morkos, A.A.1    Hopper, A.O.2    Deming, D.D.3    Yellon, S.M.4    Wycliffe, N.5    Ashwal, S.6
  • 88
    • 84901060509 scopus 로고    scopus 로고
    • Role of early life exposure and environment on neurodegeneration: implications on brain disorders
    • 24847438
    • Modgil S, Lahiri DK, Sharma VL, Anand A. Role of early life exposure and environment on neurodegeneration: implications on brain disorders. Transl Neurodegener. (2014) 3:9. 10.1186/2047-9158-3-924847438
    • (2014) Transl Neurodegener , vol.3 , pp. 9
    • Modgil, S.1    Lahiri, D.K.2    Sharma, V.L.3    Anand, A.4
  • 91
    • 56649089687 scopus 로고    scopus 로고
    • Low natural killer cell cytotoxic activity in autism: the role of glutathione, IL-2 and IL-15
    • 18929414
    • Vojdani A, Mumper E, Granpeesheh D, Mielke L, Traver D, Bock K, et al. Low natural killer cell cytotoxic activity in autism: the role of glutathione, IL-2 and IL-15. J Neuroimmunol. (2008) 205:148–54. 10.1016/j.jneuroim.2008.09.00518929414
    • (2008) J Neuroimmunol , vol.205 , pp. 148-154
    • Vojdani, A.1    Mumper, E.2    Granpeesheh, D.3    Mielke, L.4    Traver, D.5    Bock, K.6
  • 92
    • 84885426598 scopus 로고    scopus 로고
    • Altered cytokine and BDNF levels in autism spectrum disorder
    • 23604965
    • Ricci S, Businaro R, Ippoliti F, Lo Vasco VR, Massoni F, Onofri E, et al. Altered cytokine and BDNF levels in autism spectrum disorder. Neurotox Res. (2013) 24:491–501. 10.1007/s12640-013-9393-423604965
    • (2013) Neurotox Res , vol.24 , pp. 491-501
    • Ricci, S.1    Businaro, R.2    Ippoliti, F.3    Lo Vasco, V.R.4    Massoni, F.5    Onofri, E.6
  • 93
    • 79952244924 scopus 로고    scopus 로고
    • Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders
    • 21095018
    • Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah IN, Van de Water J. Associations of impaired behaviors with elevated plasma chemokines in autism spectrum disorders. J Neuroimmunol. (2011) 232:196–9. 10.1016/j.jneuroim.2010.10.02521095018
    • (2011) J Neuroimmunol , vol.232 , pp. 196-199
    • Ashwood, P.1    Krakowiak, P.2    Hertz-Picciotto, I.3    Hansen, R.4    Pessah, I.N.5    Van de Water, J.6
  • 95
    • 85067417334 scopus 로고    scopus 로고
    • Anti-inflammatory cytokines in autism spectrum disorders: a systematic review and meta-analysis
    • 31228728
    • Saghazadeh A, Ataeinia B, Keynejad K, Abdolalizadeh A, Hirbod-Mobarakeh A, Rezaei N. Anti-inflammatory cytokines in autism spectrum disorders: a systematic review and meta-analysis. Cytokine. (2019) 123:154740. 10.1016/j.cyto.2019.15474031228728
    • (2019) Cytokine , vol.123 , pp. 154740
    • Saghazadeh, A.1    Ataeinia, B.2    Keynejad, K.3    Abdolalizadeh, A.4    Hirbod-Mobarakeh, A.5    Rezaei, N.6
  • 96
    • 85045906185 scopus 로고    scopus 로고
    • Neuroimmunologic and neurotrophic interactions in autism spectrum disorders: relationship to neuroinflammation
    • 29691724
    • Ohja K, Gozal E, Fahnestock M, Cai L, Cai J, Freedman JH, et al. Neuroimmunologic and neurotrophic interactions in autism spectrum disorders: relationship to neuroinflammation. Neuromolecular Med. (2018) 20:161–73. 10.1007/s12017-018-8488-829691724
    • (2018) Neuromolecular Med , vol.20 , pp. 161-173
    • Ohja, K.1    Gozal, E.2    Fahnestock, M.3    Cai, L.4    Cai, J.5    Freedman, J.H.6
  • 97
    • 78649525669 scopus 로고    scopus 로고
    • Expression of inflammatory cytokines, Bcl2 and cathepsin D are altered in lymphoblasts of autistic subjects
    • 20399529
    • Malik M, Sheikh AM, Wen G, Spivack W, Brown WT, Li X. Expression of inflammatory cytokines, Bcl2 and cathepsin D are altered in lymphoblasts of autistic subjects. Immunobiology. (2011) 216:80–5. 10.1016/j.imbio.2010.03.00120399529
    • (2011) Immunobiology , vol.216 , pp. 80-85
    • Malik, M.1    Sheikh, A.M.2    Wen, G.3    Spivack, W.4    Brown, W.T.5    Li, X.6
  • 98
    • 85060611342 scopus 로고    scopus 로고
    • Maternal or neonatal infection: association with neonatal encephalopathy outcomes
    • Jenster M, Bonifacio SL, Ruel T, Rogers EE, Tam EW, Partridge JC, et al. Maternal or neonatal infection: association with neonatal encephalopathy outcomes. Pediatr Res. (2018) 83:747. 10.1038/pr.2017.246
    • (2018) Pediatr Res , vol.83 , pp. 747
    • Jenster, M.1    Bonifacio, S.L.2    Ruel, T.3    Rogers, E.E.4    Tam, E.W.5    Partridge, J.C.6
  • 100
    • 85047661425 scopus 로고    scopus 로고
    • Outgrowing the immaturity myth: the cost of defending from neonatal infectious disease
    • 29896192
    • Harbeson D, Ben-Othman R, Amenyogbe N, Kollmann TR. Outgrowing the immaturity myth: the cost of defending from neonatal infectious disease. Front Immunol. (2018) 9:1077. 10.3389/fimmu.2018.0107729896192
    • (2018) Front Immunol , vol.9 , pp. 1077
    • Harbeson, D.1    Ben-Othman, R.2    Amenyogbe, N.3    Kollmann, T.R.4
  • 102
    • 84877822298 scopus 로고    scopus 로고
    • Oral and inactivated poliovirus vaccines in the newborn: a review
    • 22728224
    • Mateen FJ, Shinohara RT, Sutter RW. Oral and inactivated poliovirus vaccines in the newborn: a review. Vaccine. (2013) 31:2517–24. 10.1016/j.vaccine.2012.06.02022728224
    • (2013) Vaccine , vol.31 , pp. 2517-2524
    • Mateen, F.J.1    Shinohara, R.T.2    Sutter, R.W.3
  • 103
    • 84890561886 scopus 로고    scopus 로고
    • Concurrent erythropoietin and hypothermia treatment improve outcomes in a term nonhuman primate model of perinatal asphyxia
    • 24192275
    • Traudt CM, McPherson RJ, Bauer LA, Richards TL, Burbacher TM, McAdams RM, et al. Concurrent erythropoietin and hypothermia treatment improve outcomes in a term nonhuman primate model of perinatal asphyxia. Dev Neurosci. (2013) 35:491–503. 10.1159/00035546024192275
    • (2013) Dev Neurosci , vol.35 , pp. 491-503
    • Traudt, C.M.1    McPherson, R.J.2    Bauer, L.A.3    Richards, T.L.4    Burbacher, T.M.5    McAdams, R.M.6
  • 104
    • 84873380508 scopus 로고    scopus 로고
    • Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model
    • 23183236
    • Robertson NJ, Faulkner S, Fleiss B, Bainbridge A, Andorka C, Price D, et al. Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model. Brain. (2013) 136:90–105. 10.1093/brain/aws28523183236
    • (2013) Brain , vol.136 , pp. 90-105
    • Robertson, N.J.1    Faulkner, S.2    Fleiss, B.3    Bainbridge, A.4    Andorka, C.5    Price, D.6
  • 105
    • 77953618733 scopus 로고    scopus 로고
    • Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept
    • 19861157
    • Aden U, Favrais G, Plaisant F, Winerdal M, Felderhoff-Mueser U, Lampa J, et al. Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept. Brain Behav Immun. (2010) 24:747–58. 10.1016/j.bbi.2009.10.01019861157
    • (2010) Brain Behav Immun , vol.24 , pp. 747-758
    • Aden, U.1    Favrais, G.2    Plaisant, F.3    Winerdal, M.4    Felderhoff-Mueser, U.5    Lampa, J.6
  • 106
    • 84867197336 scopus 로고    scopus 로고
    • Postnatal administration of IL-1Ra exerts neuroprotective effects following perinatal inflammation and/or hypoxic-ischemic injuries
    • Girard S, Sebire H, Brochu ME, Briota S, Sarret P, Sebire G. Postnatal administration of IL-1Ra exerts neuroprotective effects following perinatal inflammation and/or hypoxic-ischemic injuries. Brain Behav Immun. (2012) 26:1331–9. 10.1016/j.bbi.2012.09.001
    • (2012) Brain Behav Immun , vol.26 , pp. 1331-1339
    • Girard, S.1    Sebire, H.2    Brochu, M.E.3    Briota, S.4    Sarret, P.5    Sebire, G.6
  • 107
    • 79952627279 scopus 로고    scopus 로고
    • Dexamethasone pre-treatment protects brain against hypoxic-ischemic injury partially through up-regulation of vascular endothelial growth factor A in neonatal rats
    • 21277350
    • Feng Y, Rhodes PG, Bhatt AJ. Dexamethasone pre-treatment protects brain against hypoxic-ischemic injury partially through up-regulation of vascular endothelial growth factor A in neonatal rats. Neuroscience. (2011) 179:223–32. 10.1016/j.neuroscience.2011.01.05021277350
    • (2011) Neuroscience , vol.179 , pp. 223-232
    • Feng, Y.1    Rhodes, P.G.2    Bhatt, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.